Search of human proteins with 239745060

Search of human proteins with 239745060

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
         (353 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r...   746   0.0  
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r...   591   e-169
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r...   448   e-126
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r...   448   e-126
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]   443   e-125
gi|5453680 neural precursor cell expressed, developmentally down...   137   1e-32
gi|215422375 neural precursor cell expressed, developmentally do...   135   4e-32
gi|78486553 neural precursor cell expressed, developmentally dow...   127   1e-29
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...   115   6e-26
gi|55769585 HEF-like protein [Homo sapiens]                            92   5e-19
gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]               69   5e-12
gi|224177511 sorting nexin 18 isoform c [Homo sapiens]                 60   4e-09
gi|157057545 sorting nexin 18 isoform a [Homo sapiens]                 60   4e-09
gi|157057543 sorting nexin 18 isoform b [Homo sapiens]                 60   4e-09
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H...    59   5e-09
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H...    59   5e-09
gi|11321634 CD2-associated protein [Homo sapiens]                      57   2e-08
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    57   2e-08
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    57   2e-08
gi|155723000 mixed lineage kinase 4 [Homo sapiens]                     55   7e-08
gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]                55   1e-07
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               54   2e-07
gi|20149528 proline-serine-threonine phosphatase interacting pro...    54   2e-07
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    53   4e-07
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    53   4e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    52   8e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    51   2e-06
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ...    50   2e-06
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ...    50   2e-06
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ...    50   2e-06

>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 353

 Score =  746 bits (1925), Expect = 0.0
 Identities = 353/353 (100%), Positives = 353/353 (100%)

Query: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60
           MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL
Sbjct: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP 240
           VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP 240

Query: 241 ARGEPCRALTGHLSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHVEKEAVT 300
           ARGEPCRALTGHLSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHVEKEAVT
Sbjct: 241 ARGEPCRALTGHLSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHVEKEAVT 300

Query: 301 TPEASSPVRSRGTPRSSRHSKAAHEPCDWLCSQQGGGEDATQKSPRSPEKREV 353
           TPEASSPVRSRGTPRSSRHSKAAHEPCDWLCSQQGGGEDATQKSPRSPEKREV
Sbjct: 301 TPEASSPVRSRGTPRSSRHSKAAHEPCDWLCSQQGGGEDATQKSPRSPEKREV 353


>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 368

 Score =  591 bits (1523), Expect = e-169
 Identities = 284/307 (92%), Positives = 285/307 (92%), Gaps = 21/307 (6%)

Query: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60
           MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGI+PGNHL
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP 240
           VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAP 240

Query: 241 ARGEPCRALTGHLSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHVEKEAVT 300
           ARGEPCRALTGHLSQRHWA                     PQLCSSGRTLRIHVEKEAVT
Sbjct: 241 ARGEPCRALTGHLSQRHWA---------------------PQLCSSGRTLRIHVEKEAVT 279

Query: 301 TPEASSP 307
           TPEASSP
Sbjct: 280 TPEASSP 286


>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 232

 Score =  448 bits (1153), Expect = e-126
 Identities = 209/211 (99%), Positives = 210/211 (99%)

Query: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60
           MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGI+PGNHL
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
           VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211


>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 224

 Score =  448 bits (1153), Expect = e-126
 Identities = 209/211 (99%), Positives = 210/211 (99%)

Query: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60
           MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGI+PGNHL
Sbjct: 1   MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
           VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK
Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211


>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
          Length = 870

 Score =  443 bits (1140), Expect = e-125
 Identities = 206/211 (97%), Positives = 207/211 (98%)

Query: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60
           MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGI+PGN L
Sbjct: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           KILVGMYDKKPAGPGPGPPATPAQPQPGLHAP PPASQYTPMLPNTYQPQPDSVYLVPTP
Sbjct: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120

Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180
           SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV PGPGGPAQDIYQ
Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180

Query: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211
           VPPSAGMGHDIYQVP SMDTRSWEGTKPPAK
Sbjct: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAK 211



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 53/199 (26%), Positives = 74/199 (37%), Gaps = 40/199 (20%)

Query: 52  QGIMPGNHLKILVGMYDKKPA---GP-GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTY 107
           +G++P  + +    +YD  P    GP G  P        P +   +PP++ +       Y
Sbjct: 255 RGLLPSQYGQ---EVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHA-----VY 306

Query: 108 QPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV 167
              P     VP     ++  Y VP         PA     F+K  P  P  +P   L   
Sbjct: 307 DVPPSVSKDVPDGPLLREETYDVP---------PA-----FAKAKPFDPARTP---LVLA 349

Query: 168 SPGPGGP-AQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPR-G 225
           +P P  P A+D+Y VPP A    D+Y VP  +          P     V   R LPP   
Sbjct: 350 APPPDSPPAEDVYDVPPPA---PDLYDVPPGLRRPG------PGTLYDVPRERVLPPEVA 400

Query: 226 LGSPSFLLIYLSPAPARGE 244
            G      +Y  P PA  E
Sbjct: 401 DGGVVDSGVYAVPPPAERE 419


>gi|5453680 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 1 [Homo sapiens]
          Length = 834

 Score =  137 bits (346), Expect = 1e-32
 Identities = 112/329 (34%), Positives = 152/329 (46%), Gaps = 38/329 (11%)

Query: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60
           M + N++A+ALYDNV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGI+PGN +
Sbjct: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           K+L+        GP     ++  QP  GL        Q    +PN      D++Y VP P
Sbjct: 61  KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110

Query: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH---HPFPSPATDLYQVSPGPG 172
           S   QG+YQVP   G   Q  +Q PP+ Q S      PH          T    V   P 
Sbjct: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPS 170

Query: 173 GPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGL-GSPSF 231
              +D+Y +PPS      +Y +P S         K P     V     + P+G+   P  
Sbjct: 171 RYQKDVYDIPPS-HTTQGVYDIPPS-------SAKGPVFSVPVGE---IKPQGVYDIPPT 219

Query: 232 LLIYLSPAPARGEPCRALTGHLSQRH-WAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTL 290
             +Y  P  A    CR   G   + + + P + +  +P L   P      P  C+     
Sbjct: 220 KGVYAIPPSA----CRDEAGLREKDYDFPPPMRQAGRPDL--RPEGVYDIPPTCTKPAGK 273

Query: 291 RIHVEKEAVTTPEASSPVRSRGTPRSSRH 319
            +HV K     P A+ PV  R    S  H
Sbjct: 274 DLHV-KYNCDIPGAAEPVARRHQSLSPNH 301


>gi|215422375 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 3 [Homo sapiens]
          Length = 834

 Score =  135 bits (341), Expect = 4e-32
 Identities = 111/325 (34%), Positives = 150/325 (46%), Gaps = 38/325 (11%)

Query: 5   NVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILV 64
           N++A+ALYDNV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGI+PGN +K+L+
Sbjct: 5   NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64

Query: 65  GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
                   GP     ++  QP  GL        Q    +PN      D++Y VP PS   
Sbjct: 65  --------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-PSYQN 114

Query: 125 QGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH---HPFPSPATDLYQVSPGPGGPAQ 176
           QG+YQVP   G   Q  +Q PP+ Q S      PH          T    V   P    +
Sbjct: 115 QGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQK 174

Query: 177 DIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGL-GSPSFLLIY 235
           D+Y +PPS      +Y +P S         K P     V     + P+G+   P    +Y
Sbjct: 175 DVYDIPPS-HTTQGVYDIPPS-------SAKGPVFSVPVGE---IKPQGVYDIPPTKGVY 223

Query: 236 LSPAPARGEPCRALTGHLSQRH-WAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHV 294
             P  A    CR   G   + + + P + +  +P L   P      P  C+      +HV
Sbjct: 224 AIPPSA----CRDEAGLREKDYDFPPPMRQAGRPDL--RPEGVYDIPPTCTKPAGKDLHV 277

Query: 295 EKEAVTTPEASSPVRSRGTPRSSRH 319
            K     P A+ PV  R    S  H
Sbjct: 278 -KYNCDIPGAAEPVARRHQSLSPNH 301


>gi|78486553 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 2 [Homo sapiens]
          Length = 174

 Score =  127 bits (320), Expect = 1e-29
 Identities = 73/159 (45%), Positives = 95/159 (59%), Gaps = 15/159 (9%)

Query: 1   MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60
           M + N++A+ALYDNV E  +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGI+PGN +
Sbjct: 1   MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60

Query: 61  KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120
           K+L+        GP     ++  QP  GL        Q    +PN      D++Y VP P
Sbjct: 61  KLLI--------GPMQETASSHEQPASGLMQQT-FGQQKLYQVPNPQAAPRDTIYQVP-P 110

Query: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH 154
           S   QG+YQVP   G   Q  +Q PP+ Q S      PH
Sbjct: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPH 149


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score =  115 bits (288), Expect = 6e-26
 Identities = 110/336 (32%), Positives = 140/336 (41%), Gaps = 61/336 (18%)

Query: 7   LAKALYDNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIMPGNHLKILVG 65
           LA+ALYDN AESP ELSFR+GD++ VL+++   GLDGW LCSLHG+QGI+P N +K+L  
Sbjct: 9   LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66

Query: 66  MYDKKPAGPGPGP---PATPAQPQPGLHAP-----------VPPASQYTPML---PNTYQ 108
                PAGP P P   PA+PAQP     AP           VPP ++  P          
Sbjct: 67  -----PAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPAGPCP 121

Query: 109 PQPDSVYLVPTPSKAQQG-------LYQVPG-----PSPQFQSPPAKQTSTFSKQTPHHP 156
           P PD +Y +P  S  Q         +Y VP      PS      PA  +   ++  P  P
Sbjct: 122 PSPDLIYKIPRASGTQLAAPRDALEVYDVPPTALRVPSSGPYDCPASFSHPLTRVAPQPP 181

Query: 157 FPSPATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVS 216
               A     ++P P    +   +       G  IY  PS++   S       A      
Sbjct: 182 GEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLKRAS-------ALLNLYE 234

Query: 217 SPRCLPPRGLGSPSFLLIYLSP-----APARGEPCRALTGHLSQRHWAPQVTEQVQPSLS 271
           +P  L   G G  +   IY  P     AP   EP  AL  H        Q T     + S
Sbjct: 235 APEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASH-------DQDTLAQLLARS 287

Query: 272 TAPGDRAVFPQLCSSGRTLRIHVEKEAVTTPEASSP 307
             P  R   P   S  R         A+  PEA SP
Sbjct: 288 PPPPHRPRLPSAESLSRR-----PLPALPVPEAPSP 318



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 56/220 (25%), Positives = 81/220 (36%), Gaps = 68/220 (30%)

Query: 65  GMYDKKPAGPGPGPPATP----------------AQPQPGLHAPVPPASQYTPMLPNTYQ 108
           G+YD    GP   P   P                A+  P  H P  P+++     P    
Sbjct: 251 GIYDVPLLGPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRLPSAESLSRRPLPAL 310

Query: 109 PQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVS 168
           P P++    P+PS         P PSP     P ++ S   +     P P P   L    
Sbjct: 311 PVPEA----PSPS---------PVPSP----APGRKGSIQDR-----PLPPPPPRL---- 344

Query: 169 PGPGGP-------AQDIYQVPPSAGMGHDIYQVPSSMD--------TRSWEGTKPPAKCA 213
           PG GGP        +++   P  AG  ++   +P + +            +G++PP + A
Sbjct: 345 PGYGGPKVEGDPEGREMEDDP--AGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQ-A 401

Query: 214 SVSSPRCLPPRGLGSPSFLLIYLSPAPARGEPCRALTGHL 253
               P  LP RG+ +P      LSP    GEP    TG L
Sbjct: 402 CTGDPE-LPERGMPAPQEA---LSP----GEPLVVSTGDL 433


>gi|55769585 HEF-like protein [Homo sapiens]
          Length = 786

 Score = 92.4 bits (228), Expect = 5e-19
 Identities = 67/194 (34%), Positives = 90/194 (46%), Gaps = 22/194 (11%)

Query: 6   VLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVG 65
           +LA+ALYDN  +  DEL+F +GDI+T+LEQ     +GWW C LHGRQG+ P N L+IL  
Sbjct: 14  LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73

Query: 66  MYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
           +   +P  P   G    PA  +     P  P     P  P     Q  S    P P  AQ
Sbjct: 74  VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129

Query: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVSPGPGGPA-- 175
             +Y+ P P P       ++T +F KQ   T   P     P+  + +Y V     GP   
Sbjct: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVL 186

Query: 176 -----QDIYQVPPS 184
                Q +Y +P S
Sbjct: 187 KEPEKQQLYDIPAS 200


>gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]
          Length = 740

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 50/158 (31%), Positives = 74/158 (46%), Gaps = 12/158 (7%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYD 68
           KALYD   ++ DELSF +G I+ +L ++ Q  DG+W    +GR G+ P     +LV    
Sbjct: 573 KALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVFP----SVLVEELS 628

Query: 69  KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPD---SVYLVPTPSKAQQ 125
               G  P        P P  HA +PP   Y    P++  P PD   S+Y   +PS  ++
Sbjct: 629 ASENGDTPWMREIQISPSPKPHASLPPLPLY-DQPPSSPYPSPDKRSSLYFPRSPSANEK 687

Query: 126 GLY-QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPAT 162
            L+ + PG S   +  P    +++ K  P    P P T
Sbjct: 688 SLHAESPGFSQASRHTP---ETSYGKLRPVRAAPPPPT 722


>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
          Length = 591

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 46/145 (31%), Positives = 76/145 (52%), Gaps = 27/145 (18%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIMPGNHLKILV 64
           A+ALYD  +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60

Query: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113

Query: 124 -QQGLYQVPG-----------PSPQ 136
                +Q PG           PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138


>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
          Length = 624

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 46/145 (31%), Positives = 76/145 (52%), Gaps = 27/145 (18%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIMPGNHLKILV 64
           A+ALYD  +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60

Query: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113

Query: 124 -QQGLYQVPG-----------PSPQ 136
                +Q PG           PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138


>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
          Length = 628

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 46/145 (31%), Positives = 76/145 (52%), Gaps = 27/145 (18%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIMPGNHLKILV 64
           A+ALYD  +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60

Query: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113

Query: 124 -QQGLYQVPG-----------PSPQ 136
                +Q PG           PSPQ
Sbjct: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138


>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
           sapiens]
          Length = 756

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 85/374 (22%), Positives = 139/374 (37%), Gaps = 58/374 (15%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYD 68
           + L+D   E+PDEL+ R+GD++ VL + T+   GWW     GR+G+ P N +        
Sbjct: 187 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 238

Query: 69  KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQ----------PDSVYLVP 118
                  P PP     P+  +     P  +   ++P T  P           P       
Sbjct: 239 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 291

Query: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTST-------FSKQTPHHPFPSPATDLY 165
           TPS+  Q L  +  GP+  FQS     P  K++ T        S Q   H  P  A  + 
Sbjct: 292 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 351

Query: 166 QVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASV----SSPRCL 221
           + +P P   A    + PP+        ++P+     S E T      AS+    +S +  
Sbjct: 352 R-TPMPDKTATP--ERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIP 408

Query: 222 PPRGLGSPSFLLIYLSPAPARGEPCRALTGHLSQRHWAPQVTEQV-----QPSLSTAPGD 276
            P  + +P  +   ++P      P  ++    +     P   E+V      P+L   P D
Sbjct: 409 APDKVPTPEKM---VTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMD 465

Query: 277 RAVFPQLCSSGRTLRIHVEKEAVTTPEASSPVRSRGTPRSSRH--SKAAHEPCDWLCSQQ 334
           +   P++   G         E V TPE S    S        H  S+ A +   +  +++
Sbjct: 466 KVPNPKMAPLGDEA---PTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKE 522

Query: 335 GGGEDATQKSPRSP 348
                    +P +P
Sbjct: 523 DPSSQEEAHTPEAP 536



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 19/105 (18%)

Query: 17  ESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYDKKPAGPGP 76
           E  DEL  + G+I+ ++++     DGWWL   +G+ G  P N +++L    D  P  P  
Sbjct: 97  EQADELKLQAGEIVEMIKEIE---DGWWLGKKNGQLGAFPSNFVELL----DSGP--PSL 147

Query: 77  GPPATPAQPQPGLHAPVPPASQYTPMLPN-TYQPQPDSVYLVPTP 120
           G P  P+         V P  Q  P L +  Y   PD +  V  P
Sbjct: 148 GNPDMPS---------VSPGPQRPPKLSSLAYDSPPDYLQTVSHP 183


>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
           sapiens]
          Length = 645

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 85/374 (22%), Positives = 139/374 (37%), Gaps = 58/374 (15%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYD 68
           + L+D   E+PDEL+ R+GD++ VL + T+   GWW     GR+G+ P N +        
Sbjct: 76  RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 127

Query: 69  KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQ----------PDSVYLVP 118
                  P PP     P+  +     P  +   ++P T  P           P       
Sbjct: 128 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 180

Query: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTST-------FSKQTPHHPFPSPATDLY 165
           TPS+  Q L  +  GP+  FQS     P  K++ T        S Q   H  P  A  + 
Sbjct: 181 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 240

Query: 166 QVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASV----SSPRCL 221
           + +P P   A    + PP+        ++P+     S E T      AS+    +S +  
Sbjct: 241 R-TPMPDKTATP--ERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIP 297

Query: 222 PPRGLGSPSFLLIYLSPAPARGEPCRALTGHLSQRHWAPQVTEQV-----QPSLSTAPGD 276
            P  + +P  +   ++P      P  ++    +     P   E+V      P+L   P D
Sbjct: 298 APDKVPTPEKM---VTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMD 354

Query: 277 RAVFPQLCSSGRTLRIHVEKEAVTTPEASSPVRSRGTPRSSRH--SKAAHEPCDWLCSQQ 334
           +   P++   G         E V TPE S    S        H  S+ A +   +  +++
Sbjct: 355 KVPNPKMAPLGDEA---PTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKE 411

Query: 335 GGGEDATQKSPRSP 348
                    +P +P
Sbjct: 412 DPSSQEEAHTPEAP 425



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 16/81 (19%)

Query: 41  DGWWLCSLHGRQGIMPGNHLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYT 100
           DGWWL   +G+ G  P N +++L    D  P  P  G P  P+         V P  Q  
Sbjct: 7   DGWWLGKKNGQLGAFPSNFVELL----DSGP--PSLGNPDMPS---------VSPGPQRP 51

Query: 101 PMLPN-TYQPQPDSVYLVPTP 120
           P L +  Y   PD +  V  P
Sbjct: 52  PKLSSLAYDSPPDYLQTVSHP 72


>gi|11321634 CD2-associated protein [Homo sapiens]
          Length = 639

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 20/159 (12%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYD 68
           + L+     + DEL+F++G+I+ ++ ++T G  GWW   L+G++G+ P N   + +   D
Sbjct: 275 RTLFAYEGTNEDELTFKEGEIIHLISKET-GEAGWWRGELNGKEGVFPDN-FAVQINELD 332

Query: 69  KK-PAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGL 127
           K  P    P PPA    P+P L   +    +Y  + P   + + +   L   PSK     
Sbjct: 333 KDFPKPKKPPPPAKAPAPKPEL---IAAEKKYFSLKP---EEKDEKSTLEQKPSKP---- 382

Query: 128 YQVPGPSPQFQSPPAK------QTSTFSKQTPHHPFPSP 160
              P   P+  +PP K       + T   + P  P P P
Sbjct: 383 -AAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPP 420



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 3/55 (5%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKIL 63
           K L++ + ++ DEL  + GDI+ + E+     +GWW  +L+ + G+ P N +K L
Sbjct: 114 KVLFEYIPQNEDELELKVGDIIDINEEVE---EGWWSGTLNNKLGLFPSNFVKEL 165



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 2/50 (4%)

Query: 12 YDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLK 61
          YD  A   DEL+ R G+I+  +++  +  +GW    L+GR+G+ P N +K
Sbjct: 8  YDYDAVHDDELTIRVGEIIRNVKKLQE--EGWLEGELNGRRGMFPDNFVK 55


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 2/79 (2%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYD 68
           K ++   A++ DEL+ ++GDI+T++ +D   + GWW   L+GR+G+ P N +K+L   ++
Sbjct: 236 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFE 294

Query: 69  KKPAGP-GPGPPATPAQPQ 86
           K+   P  P PP+ P   Q
Sbjct: 295 KEGNRPKKPPPPSAPVIKQ 313



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 12  YDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYDK 69
           +  + ++ DEL  + GDI+ V+ +  +G   WW   L+G+ G+ P N +K L G  D+
Sbjct: 70  FSYLPQNDDELELKVGDIIEVVGEVEEG---WWEGVLNGKTGMFPSNFIKELSGESDE 124


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 2/79 (2%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYD 68
           K ++   A++ DEL+ ++GDI+T++ +D   + GWW   L+GR+G+ P N +K+L   ++
Sbjct: 273 KVIFPYEAQNDDELTIKEGDIVTLINKDCIDV-GWWEGELNGRRGVFPDNFVKLLPPDFE 331

Query: 69  KKPAGP-GPGPPATPAQPQ 86
           K+   P  P PP+ P   Q
Sbjct: 332 KEGNRPKKPPPPSAPVIKQ 350



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 12  YDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYDK 69
           +  + ++ DEL  + GDI+ V+ +  +G   WW   L+G+ G+ P N +K L G  D+
Sbjct: 107 FSYLPQNDDELELKVGDIIEVVGEVEEG---WWEGVLNGKTGMFPSNFIKELSGESDE 161



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 3/60 (5%)

Query: 12 YDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMYDKKP 71
          +D  A+  DEL+   G+I+T + ++     GWW   ++GR+G+ P N ++ +     K P
Sbjct: 8  FDYQAQHDDELTISVGEIITNIRKED---GGWWEGQINGRRGLFPDNFVREIKKEMKKDP 64


>gi|155723000 mixed lineage kinase 4 [Homo sapiens]
          Length = 1036

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 30/83 (36%), Positives = 40/83 (48%), Gaps = 11/83 (13%)

Query: 10  ALYDNVAESPDELSFRKGDIMTVLEQD--TQGLDGWWLCSLHGRQGIMPGNHLKILVGMY 67
           ALYD  A   DELS R+G ++ VL QD    G +GWW   +  R GI P N++       
Sbjct: 45  ALYDYEARGEDELSLRRGQLVEVLSQDAAVSGDEGWWAGQVQRRLGIFPANYV------- 97

Query: 68  DKKPAGPGPGPPATPAQPQPGLH 90
              P  P   P   P++P   +H
Sbjct: 98  --APCRPAASPAPPPSRPSSPVH 118


>gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]
          Length = 690

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 43/153 (28%), Positives = 69/153 (45%), Gaps = 15/153 (9%)

Query: 7   LAKALYDNVAESPDELSFRKGDIMTVLEQDTQGL-DGWWLCSLHGRQGIMPGNHLKILVG 65
           LA+ALY    +S +ELSF +G ++ +L +   G+ DG+W     GR G+ P   ++ L+G
Sbjct: 550 LAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFPSLLVEELLG 609

Query: 66  MYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQ 125
                     PGPP   + P+  L +P PP+  ++P  P +    P +  L    +    
Sbjct: 610 ---------PPGPPEL-SDPEQMLPSPSPPS--FSPPAPTSVLDGPPAPVLPGDKALDFP 657

Query: 126 GLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFP 158
           G   +  P  +   PP    +      P HP P
Sbjct: 658 GFLDMMAPRLRPMRPPPPPPA--KAPDPGHPDP 688


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 59/225 (26%), Positives = 81/225 (36%), Gaps = 29/225 (12%)

Query: 69  KKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLY 128
           ++P  PGPG P  P   QP L  P+ P       LP  +QPQP      P P    Q  +
Sbjct: 558 RQPFLPGPGQPFLPTHTQPNLQGPLHPP------LPPPHQPQPQQPQQQPPPQ--HQPPH 609

Query: 129 QVP-GPSPQFQSP---PAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPS 184
           Q P  P PQ Q P   P +          HH    P   L  +S     P     Q   S
Sbjct: 610 QPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQAS 669

Query: 185 AGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAPARGE 244
           +       +     +T S   +K P +    ++PR    R L      +I +S +     
Sbjct: 670 SSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSAT 729

Query: 245 PCRALTGHLSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRT 289
           P                 + QV+P +S +P  RAV     S G+T
Sbjct: 730 P-----------------SAQVKPIVSASPPSRAVAGSRSSQGKT 757



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 67/268 (25%), Positives = 87/268 (32%), Gaps = 45/268 (16%)

Query: 71  PAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLP--NTYQPQPDSVYLVPTPSKAQQGLY 128
           P  P P PP    QP   L  P P      P+LP  + + P P     +P   +  + + 
Sbjct: 317 PQAPPPPPPPPQQQPIRSLFQPQP----LQPLLPVQHPHHPSPPQGMHMPPQLETPRMMM 372

Query: 129 QVPGPSPQ-----FQSPPAKQTSTFSKQTPHHPFPS---PATDLYQVSPGP-------GG 173
             P  +PQ       +P  K T     Q P  P PS   PA    Q  PGP        G
Sbjct: 373 TPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVG-PQRFPGPPEFPQHTPG 431

Query: 174 PAQDIYQVPPSAGMGHDIYQVPSSMDTR-------SWEGTKPPAKCASVSSPRCLPPRGL 226
           P  + +  PP   +  D ++ P     R       S E   P        SP   PP   
Sbjct: 432 PVPNSFSQPPRLPL-QDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPP--- 487

Query: 227 GSPSFLLIYLSPAPARGEPCRALTGHLSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCSS 286
             P  LL    P P +          L      P   +Q Q  +   P +R V P L   
Sbjct: 488 --PPTLLNSSHPVPTQSP--------LPFTQPGPAFNQQGQQPV--FPRERPVRPALQPP 535

Query: 287 GRTLRIHVEKEAVTTPEASSPVRSRGTP 314
           G    +H  +    T     P R    P
Sbjct: 536 GPVGILHFSQPGSATTRPFIPPRQPFLP 563


>gi|20149528 proline-serine-threonine phosphatase interacting
           protein 1 [Homo sapiens]
          Length = 416

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 24/55 (43%), Positives = 37/55 (67%), Gaps = 3/55 (5%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKIL 63
           +ALYD  A++PDEL    GDI+ V+    +G DGWW    +G++G +PG++L+ L
Sbjct: 365 RALYDYTAQNPDELDLSAGDILEVI---LEGEDGWWTVERNGQRGFVPGSYLEKL 416


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 24/50 (48%), Positives = 34/50 (68%)

Query: 10  ALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNH 59
           AL+D  AE  DELSFR+G+ +TVL +D      WW  +LHG++G +P N+
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNY 814



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 45/163 (27%), Positives = 58/163 (35%), Gaps = 32/163 (19%)

Query: 71  PAGPGPGPPATPAQPQP---GLHAPVPPASQY------TPMLPNTYQPQ-PDSVYLVPTP 120
           P   GP  P T  +P+P   GL  PV  A          P+ P   QP  P     VP  
Sbjct: 448 PVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPEL 507

Query: 121 SKAQQGLYQVPGP----SPQFQSPPAKQTSTFSKQ---------------TPHHPFP--S 159
            +  + L ++P P        Q+P      T  KQ                P  P P  S
Sbjct: 508 EEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELS 567

Query: 160 PATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRS 202
           P T+  +   GP  PA     +PP A       + P SM+ RS
Sbjct: 568 PITEGSEARAGPPAPAPPA-PIPPPAPSQSSPPEQPQSMEMRS 609



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 9/125 (7%)

Query: 70  KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG--- 126
           +P    P PP++P         P+P +  +   L N +     S  ++P      +    
Sbjct: 347 QPVSRIPMPPSSPQPRGAPRQRPIPLSMIFK--LQNAFWEHGASRAMLPGSPLFTRAPPP 404

Query: 127 -LYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLY---QVSPGPGGPAQDIYQVP 182
            L   P P PQ QS P  Q     +  P  P P+P         V+ GP  P  ++   P
Sbjct: 405 KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEP 464

Query: 183 PSAGM 187
              G+
Sbjct: 465 EIEGL 469


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 24/50 (48%), Positives = 34/50 (68%)

Query: 10  ALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNH 59
           AL+D  AE  DELSFR+G+ +TVL +D      WW  +LHG++G +P N+
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNY 814



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 45/163 (27%), Positives = 58/163 (35%), Gaps = 32/163 (19%)

Query: 71  PAGPGPGPPATPAQPQP---GLHAPVPPASQY------TPMLPNTYQPQ-PDSVYLVPTP 120
           P   GP  P T  +P+P   GL  PV  A          P+ P   QP  P     VP  
Sbjct: 448 PVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPEL 507

Query: 121 SKAQQGLYQVPGP----SPQFQSPPAKQTSTFSKQ---------------TPHHPFP--S 159
            +  + L ++P P        Q+P      T  KQ                P  P P  S
Sbjct: 508 EEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELS 567

Query: 160 PATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRS 202
           P T+  +   GP  PA     +PP A       + P SM+ RS
Sbjct: 568 PITEGSEARAGPPAPAPPA-PIPPPAPSQSSPPEQPQSMEMRS 609



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 9/125 (7%)

Query: 70  KPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG--- 126
           +P    P PP++P         P+P +  +   L N +     S  ++P      +    
Sbjct: 347 QPVSRIPMPPSSPQPRGAPRQRPIPLSMIFK--LQNAFWEHGASRAMLPGSPLFTRAPPP 404

Query: 127 -LYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLY---QVSPGPGGPAQDIYQVP 182
            L   P P PQ QS P  Q     +  P  P P+P         V+ GP  P  ++   P
Sbjct: 405 KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEP 464

Query: 183 PSAGM 187
              G+
Sbjct: 465 EIEGL 469


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 80/307 (26%), Positives = 106/307 (34%), Gaps = 45/307 (14%)

Query: 71   PAGPGPG-----PPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQ 125
            PA P P      P ATP  P+ G   P  P+ ++ P  P    P P      P+P  A  
Sbjct: 931  PASPSPKGAPTPPAATPPSPKGG---PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987

Query: 126  GLYQVPGPSPQF--QSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPP 183
                 P PSP+    +P  K   T    TP  P  SPA      +P P G +      PP
Sbjct: 988  PPAATP-PSPKGGPATPSPKGAPTPPAVTPPSPKGSPA-----ATPFPKGASTPPAATPP 1041

Query: 184  SAGMGHDIYQVPSSMDTRSWE-------GTKPPAKCASVSSPRCLPPRGLGSPSFLLIYL 236
            S         +P    T           G   P+   + + P   PP   G P+      
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101

Query: 237  SPAPARGEPCRALTGHLSQRHWAPQVTEQVQP-----SLST-----APGDRAVFPQLCSS 286
            +P P    P     G  +  H     T    P      L+T     AP   A  P     
Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161

Query: 287  GRTLRIHVEKEAVTTPEASSPVRSRG----TPRSSRHSKAAHEPCDWLCSQQGGGEDATQ 342
            G  L     K A TTP A+ P    G    +P+ +  + AA  P     S +GG    + 
Sbjct: 1162 G--LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-----SPKGGLATPSP 1214

Query: 343  K-SPRSP 348
            K +P +P
Sbjct: 1215 KGAPTTP 1221



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 78/309 (25%), Positives = 102/309 (33%), Gaps = 40/309 (12%)

Query: 65   GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
            G+    P G    P ATP  P+ GL  P P  +   P  P    P P      P+P  A 
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGA---PTTPAATPPSPKGGLATPSPKGAP 1241

Query: 125  QGLYQVPGPSPQF--QSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGP---------GG 173
                  P PSP+    +PP K   T    TP       AT  ++ +P P         GG
Sbjct: 1242 TTPAATP-PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300

Query: 174  PAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLL 233
            PA      PP           PS    +   GT PP    + + P   PP   G+P+   
Sbjct: 1301 PATS----PPKGAPTPPAATPPS---PKGSPGTPPPK--GAPTPPAVTPPSPKGTPTLPA 1351

Query: 234  IYLS-------PAPARG-EPCRALTGHLSQRHWAPQVTEQ--VQPSLSTAPGDRAVFPQL 283
               S       P+   G  P  A   H       P   ++    PS    P   AV P  
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP-- 1409

Query: 284  CSSGRTLRIHVEKEAVTTPEASSPVRSRGTPRSSRHSKAAHEPCDWLCSQQGGGED---- 339
             S  +     V +E   TP          TP S + + A   P     +    G+     
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469

Query: 340  ATQKSPRSP 348
             T  SP+ P
Sbjct: 1470 VTPPSPKEP 1478



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 63/252 (25%), Positives = 85/252 (33%), Gaps = 45/252 (17%)

Query: 65   GMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
            G+    P G    P ATP  P+ GL  P P  +   P  P    P P      P+P  A 
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGA---PTTPAATPPSPKGGLATPSPKGAP 1195

Query: 125  QGLYQVPGPSPQ--FQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVP 182
                  P PSP+    +P  K   T    TP    PSP   L   +P P G        P
Sbjct: 1196 TTPAATP-PSPKGGLATPSPKGAPTTPAATP----PSPKGGL--ATPSPKGAPTTPAATP 1248

Query: 183  PSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAPAR 242
            PS   G      P      +     PP+    +++P   P +G  +P+     ++P   +
Sbjct: 1249 PSPKGGP---ATPPPKGAPTPPAATPPSLKGGLATP---PHKGAPNPA----VVTPPSPK 1298

Query: 243  GEPCRALTGHLSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHVEKEAVTTP 302
            G P        S    AP       PS   +PG                     +   TP
Sbjct: 1299 GGPA------TSPPKGAPTPPAATPPSPKGSPGT-----------------PPPKGAPTP 1335

Query: 303  EASSPVRSRGTP 314
             A +P   +GTP
Sbjct: 1336 PAVTPPSPKGTP 1347



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 63/239 (26%), Positives = 81/239 (33%), Gaps = 45/239 (18%)

Query: 78   PPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQ- 136
            P ATP  P+ GL  P P  +   P  P    P P      P P  A       P PSP+ 
Sbjct: 1129 PAATPPSPKGGLATPPPKGA---PTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKG 1184

Query: 137  -FQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVP 195
               +P  K   T    TP    PSP   L   +P P G        PPS   G      P
Sbjct: 1185 GLATPSPKGAPTTPAATP----PSPKGGL--ATPSPKGAPTTPAATPPSPKGG---LATP 1235

Query: 196  SSMDTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAPARGEPCRALTGHLSQ 255
            S     +     PP+     ++P   PP+G  +P          PA   P  +L G L+ 
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATP---PPKGAPTP----------PAATPP--SLKGGLA- 1279

Query: 256  RHWAPQVTEQVQPSLSTAPGDRAVFPQLCSSGRTLRIHVEKEAVTTPEASSPVRSRGTP 314
                        P    AP    V P     G         +   TP A++P   +G+P
Sbjct: 1280 -----------TPPHKGAPNPAVVTPPSPKGGPATS---PPKGAPTPPAATPPSPKGSP 1324



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 65/297 (21%), Positives = 93/297 (31%), Gaps = 31/297 (10%)

Query: 55   MPGNHLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPV-------PPASQYTPMLPNT- 106
            +P N L    G  D       P PP+    P P    P+       PP    TP + N  
Sbjct: 836  LPENSLSFQ-GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP 894

Query: 107  ------YQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSP 160
                    P P     +   S + +     P P     SP  K   T    TP  P   P
Sbjct: 895  FPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954

Query: 161  ATDLYQVSPGPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRC 220
            AT   + +P P        +  P+          P++       G   P+   + + P  
Sbjct: 955  ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014

Query: 221  LPPRGLGSPSFLLIYLSPAPARGEPCRALTGHLSQRHWAPQVTEQVQPSLSTAP-GDRAV 279
             PP   GSP+      +P P       A T        +P+ +    P    AP    A 
Sbjct: 1015 TPPSPKGSPA-----ATPFPKGASTPPAATPP------SPKGSPAATPLPKGAPTTPAAT 1063

Query: 280  FPQLCSSGRTLRIHVEKEAVTTPEASSPVRSRGTPRSSRHSKAAHEPCDWLCSQQGG 336
             P       T  +    +   TP A++P   +G P +     A   P     S +GG
Sbjct: 1064 LPSPKGGPATPSL----KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 66/271 (24%), Positives = 94/271 (34%), Gaps = 38/271 (14%)

Query: 69   KKPAGPGP-GPPATPAQP-QPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG 126
            K PA   P G PATP+    P L A  PP    +P  P    P P  V    +P KA   
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPP----SPKEP----PAPKQVATSSSPKKAPAT 1496

Query: 127  LYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPSAG 186
               +  P+     P + +    +  +   P    AT L + +P    P + +  +PP+  
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL--IPPA-- 1552

Query: 187  MGHDIYQVPSSMDTRS----WEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSPAPAR 242
                   VPS   T +     E    P+   + S P   P    G+PS   + + PA   
Sbjct: 1553 -----MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS 1607

Query: 243  GEPCRALTGHLSQRHWAPQVTE------QVQPSLSTAPGDRAVFPQLCSSGRTLRIHVE- 295
              P  A T         P VT          P+    P    V P       T    V  
Sbjct: 1608 PSPKEAPT--------PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659

Query: 296  KEAVTTPEASSPVRSRGTPRSSRHSKAAHEP 326
            K   T P+AS  + ++  P + +    A  P
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 21/70 (30%), Positives = 28/70 (40%), Gaps = 6/70 (8%)

Query: 93  VPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQT 152
           VP   Q  P      QPQ ++  L  + + +       PGP+      PA Q    S   
Sbjct: 9   VPATEQELP------QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62

Query: 153 PHHPFPSPAT 162
              PFPSP+T
Sbjct: 63  QASPFPSPST 72



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 65/297 (21%), Positives = 106/297 (35%), Gaps = 37/297 (12%)

Query: 82  PAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPS----------KAQQGLYQVP 131
           P  P    + PV P+ Q T     T    P+    VP+PS          K   G+    
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758

Query: 132 GPSPQFQSPPAKQT-------STFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPPS 184
             +P   SP    T       +  SK T  +   SP+     VSP    P        P 
Sbjct: 759 ALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818

Query: 185 AGMGH---DIYQVPSSM---DTRSWEGTKPPAKCASVSSPRCLPPRGLGSPSFLLIYLSP 238
             +G+    +  V +S    ++ S++G+K     A+  SP    P+G  +PS  +  LSP
Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSFQGSKDSP--ATTHSPTPPSPKGAPTPS-AVTPLSP 875

Query: 239 ----APARGEPCRALTGHLSQRHWAPQVTEQVQPSL---STAPGDRAVFPQLCSSGRTLR 291
                P +  P  ++      +        +  P+L   S++P      P    + + + 
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP----APKGIP 931

Query: 292 IHVEKEAVTTPEASSPVRSRGTPRSSRHSKAAHEPCDWLCSQQGGGEDATQKSPRSP 348
                +   TP A++P   +G P +     A   P     S +GG    + K   +P
Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 58/210 (27%), Positives = 73/210 (34%), Gaps = 37/210 (17%)

Query: 68  DKKPAGPGPG-----PPATPAQPQPGLHAPVPPASQYTPMLPNTYQ----PQPDSVYLVP 118
           ++ P GPGPG     PP  P  P P      PP  Q  P  P  +Q    PQP      P
Sbjct: 43  NRGPMGPGPGQSGPKPPIPP--PPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPP 100

Query: 119 TP--SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTP-------HHPFPSPATDLYQVSP 169
            P    ++  + Q PGP+P   S P   +S      P         P P+P       S 
Sbjct: 101 PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSA 160

Query: 170 GPGGPAQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKCASVSSPRCLPPR--GLG 227
            PG P       PPS+G           + T   +   PP   A+V  P   P +  G G
Sbjct: 161 PPGAPP----PTPPSSG-----------VPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPG 205

Query: 228 SPSFLLIYLSPAPARGEPCRALTGHLSQRH 257
            P    +   P P  G       GH    H
Sbjct: 206 GPKGGKMPGGPKPGGGPGLSTPGGHPKPPH 235



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 38/130 (29%), Positives = 42/130 (32%), Gaps = 33/130 (25%)

Query: 71  PAGPGPGPPATP----AQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG 126
           P G GPGP  TP        PG   P PP+S      P    P P     VP P     G
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPA-AVPGPG---PG 197

Query: 127 LYQVPGP----------SPQFQSPPAKQTSTFSKQTP------------HHPFPSPATDL 164
             Q PGP           P+    P   T     + P            HHP   P    
Sbjct: 198 PKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP---PYHQQ 254

Query: 165 YQVSPGPGGP 174
           +   P PGGP
Sbjct: 255 HHQGPPPGGP 264


>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
           sapiens]
          Length = 492

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 8/78 (10%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMY 67
           AKA+YD  A++  ELSF+KGD + +L +  Q    W+    HGR GI P ++++ L    
Sbjct: 260 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQ---NWYEGEHHGRVGIFPISYVEKLTPPE 316

Query: 68  DKKPAGPGPGPPATPAQP 85
             +PA P P     PAQP
Sbjct: 317 KAQPARPPP-----PAQP 329



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQ--GIMPGNHLKIL 63
           +ALY+    + DEL  R+ D++ V+E+     DGW++ +    +  G  PGN++K L
Sbjct: 439 QALYNYTPRNEDELELRESDVIDVMEKCD---DGWFVGTSRRTKFFGTFPGNYVKRL 492



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 7/86 (8%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHG--RQGIMPGNHLKILVG 65
           A A Y+  A++  ELS RKGD + +L++  Q    W+   + G  RQGI P ++++++  
Sbjct: 335 AIAKYNFNADTNVELSLRKGDRVILLKRVDQ---NWYEGKIPGTNRQGIFPVSYVEVV-- 389

Query: 66  MYDKKPAGPGPGPPATPAQPQPGLHA 91
             + K A   P PP   +     +H+
Sbjct: 390 KKNTKGAEDYPDPPIPHSYSSDRIHS 415



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 44/162 (27%), Positives = 62/162 (38%), Gaps = 20/162 (12%)

Query: 81  TPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSP 140
           TP     GL+ P   A  +      TY+P   S +   +P+  +     VP P      P
Sbjct: 39  TPYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKS-HSDNSPNAFKDASSPVPPPHVPPPVP 97

Query: 141 PAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPP--SAGMGHD----IYQV 194
           P +     S +      P    D  +    P    + I++  P  S+ + H+    +YQ 
Sbjct: 98  PLRPRDRSSTEKHDWDPPDRKVDTRKFRSEP----RSIFEYEPGKSSILQHERPASLYQ- 152

Query: 195 PSSMDTRSWEGTKPPAKCAS------VSSPRCLPPRGLGSPS 230
            SS+D RS E     A  AS       S P   PPRGLG  S
Sbjct: 153 -SSID-RSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQS 192


>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
           sapiens]
          Length = 1004

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 8/78 (10%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMY 67
           AKA+YD  A++  ELSF+KGD + +L +  Q    W+    HGR GI P ++++ L    
Sbjct: 772 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQ---NWYEGEHHGRVGIFPISYVEKLTPPE 828

Query: 68  DKKPAGPGPGPPATPAQP 85
             +PA P P     PAQP
Sbjct: 829 KAQPARPPP-----PAQP 841



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 55/213 (25%), Positives = 80/213 (37%), Gaps = 30/213 (14%)

Query: 86  QPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQT 145
           +PGL+ P   A  +      TY+P   S +   +P+  +     VP P      PP +  
Sbjct: 29  KPGLYNPPYSAQSHPAAKTQTYRPLSKS-HSDNSPNAFKDASSPVPPPHVPPPVPPLRPR 87

Query: 146 STFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPP--SAGMGHD----IYQVPSSMD 199
              S +      P    D  +    P    + I++  P  S+ + H+    +YQ  SS+D
Sbjct: 88  DRSSTEKHDWDPPDRKVDTRKFRSEP----RSIFEYEPGKSSILQHERPASLYQ--SSID 141

Query: 200 TRSWEGTKPPAKCAS------VSSPRCLPPRGLGSPSFLLIYLSPAPARGEPCRA-LTGH 252
            RS E     A  AS       S P   PPRGLG  S          +R  P R  L G 
Sbjct: 142 -RSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQS---------ASRTSPGRVDLPGS 191

Query: 253 LSQRHWAPQVTEQVQPSLSTAPGDRAVFPQLCS 285
            +    +   +    PS +    D  + P LCS
Sbjct: 192 STTLTKSFTSSSPSSPSRAKGGDDSKICPSLCS 224



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 9    KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQ--GIMPGNHLKIL 63
            +ALY+    + DEL  R+ D++ V+E+     DGW++ +    +  G  PGN++K L
Sbjct: 951  QALYNYTPRNEDELELRESDVIDVMEKCD---DGWFVGTSRRTKFFGTFPGNYVKRL 1004



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 7/86 (8%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHG--RQGIMPGNHLKILVG 65
           A A Y+  A++  ELS RKGD + +L++  Q    W+   + G  RQGI P ++++++  
Sbjct: 847 AIAKYNFNADTNVELSLRKGDRVILLKRVDQ---NWYEGKIPGTNRQGIFPVSYVEVV-- 901

Query: 66  MYDKKPAGPGPGPPATPAQPQPGLHA 91
             + K A   P PP   +     +H+
Sbjct: 902 KKNTKGAEDYPDPPIPHSYSSDRIHS 927


>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
           sapiens]
          Length = 824

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 8/78 (10%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVGMY 67
           AKA+YD  A++  ELSF+KGD + +L +  Q    W+    HGR GI P ++++ L    
Sbjct: 592 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQ---NWYEGEHHGRVGIFPISYVEKLTPPE 648

Query: 68  DKKPAGPGPGPPATPAQP 85
             +PA P P     PAQP
Sbjct: 649 KAQPARPPP-----PAQP 661



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 9   KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQ--GIMPGNHLKIL 63
           +ALY+    + DEL  R+ D++ V+E+     DGW++ +    +  G  PGN++K L
Sbjct: 771 QALYNYTPRNEDELELRESDVIDVMEKCD---DGWFVGTSRRTKFFGTFPGNYVKRL 824



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 7/86 (8%)

Query: 8   AKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHG--RQGIMPGNHLKILVG 65
           A A Y+  A++  ELS RKGD + +L++  Q    W+   + G  RQGI P ++++++  
Sbjct: 667 AIAKYNFNADTNVELSLRKGDRVILLKRVDQ---NWYEGKIPGTNRQGIFPVSYVEVV-- 721

Query: 66  MYDKKPAGPGPGPPATPAQPQPGLHA 91
             + K A   P PP   +     +H+
Sbjct: 722 KKNTKGAEDYPDPPIPHSYSSDRIHS 747



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 25/180 (13%)

Query: 71  PAGPGPGPPATPA-QPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQ 129
           P  P P PP  P  +     H   PP  +        ++ +P S++    P K+    ++
Sbjct: 350 PHVPPPVPPLRPRDRSSTEKHDWDPPDRKVDT---RKFRSEPRSIFEYE-PGKSSILQHE 405

Query: 130 VPGPSPQFQSP----PAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQVPP-- 183
            P P P   +P    P ++  + S+       PSP       +P    PA    + P   
Sbjct: 406 RPPPLPTTPTPVPREPGRKPLSSSRLGEVTGSPSPPPRSGAPTPSSRAPALSPTRPPKKP 465

Query: 184 -------SAGMGHDIYQVPSSMDTRSWEGTKPPAKCAS------VSSPRCLPPRGLGSPS 230
                  S+G+ ++     SS+D RS E     A  AS       S P   PPRGLG  S
Sbjct: 466 LDYVQDHSSGVFNEASLYQSSID-RSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQS 524


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,680,379
Number of Sequences: 37866
Number of extensions: 1491103
Number of successful extensions: 11670
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 315
Number of HSP's successfully gapped in prelim test: 1005
Number of HSP's that attempted gapping in prelim test: 6872
Number of HSP's gapped (non-prelim): 3874
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.