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Search of human proteins with 239744892
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239744892 PREDICTED: hypothetical protein XP_002344252 [Homo
sapiens]
(557 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239744892 PREDICTED: hypothetical protein XP_002344252 [Homo ... 1176 0.0
gi|62122917 filaggrin family member 2 [Homo sapiens] 126 6e-29
gi|57864582 hornerin [Homo sapiens] 111 2e-24
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 65 2e-10
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 62 1e-09
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 59 9e-09
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 59 9e-09
gi|217330641 IWS1 homolog [Homo sapiens] 58 3e-08
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap... 55 2e-07
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 53 6e-07
gi|60097902 filaggrin [Homo sapiens] 52 1e-06
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa... 48 2e-05
gi|38261962 activating transcription factor 7 interacting protei... 44 3e-04
gi|22749325 zinc finger protein 48 [Homo sapiens] 44 3e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 43 9e-04
gi|22027597 alpha 1 type XIII collagen isoform 13 [Homo sapiens] 42 0.001
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 42 0.002
gi|9955931 acrosomal vesicle protein 1 isoform d precursor [Homo... 42 0.002
gi|9955941 acrosomal vesicle protein 1 isoform h precursor [Homo... 42 0.002
gi|169213237 PREDICTED: hypothetical protein [Homo sapiens] 40 0.007
gi|169212746 PREDICTED: hypothetical protein [Homo sapiens] 40 0.007
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 40 0.007
gi|22027595 alpha 1 type XIII collagen isoform 12 [Homo sapiens] 40 0.007
gi|22027601 alpha 1 type XIII collagen isoform 15 [Homo sapiens] 39 0.010
gi|9955933 acrosomal vesicle protein 1 isoform e precursor [Homo... 39 0.010
gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ... 39 0.013
gi|33286446 opioid growth factor receptor [Homo sapiens] 38 0.028
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 37 0.036
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 37 0.036
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 37 0.048
>gi|239744892 PREDICTED: hypothetical protein XP_002344252 [Homo
sapiens]
Length = 557
Score = 1176 bits (3041), Expect = 0.0
Identities = 557/557 (100%), Positives = 557/557 (100%)
Query: 1 MTESRSSSSWGQRRRLEERRQIARLFLTPRFCDLSALGVLRCLVSYRGDRKHGDTPSPLS 60
MTESRSSSSWGQRRRLEERRQIARLFLTPRFCDLSALGVLRCLVSYRGDRKHGDTPSPLS
Sbjct: 1 MTESRSSSSWGQRRRLEERRQIARLFLTPRFCDLSALGVLRCLVSYRGDRKHGDTPSPLS 60
Query: 61 GDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDA 120
GDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDA
Sbjct: 61 GDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDA 120
Query: 121 PSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDR 180
PSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDR
Sbjct: 121 PSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDR 180
Query: 181 THGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSR 240
THGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSR
Sbjct: 181 THGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSR 240
Query: 241 LSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHG 300
LSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHG
Sbjct: 241 LSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHG 300
Query: 301 DAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGG 360
DAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGG
Sbjct: 301 DAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGG 360
Query: 361 DRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDAL 420
DRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDAL
Sbjct: 361 DRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDAL 420
Query: 421 SRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRT 480
SRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRT
Sbjct: 421 SRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRT 480
Query: 481 HGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPL 540
HGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPL
Sbjct: 481 HGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPL 540
Query: 541 SGDHQLLCPWIGTHWVE 557
SGDHQLLCPWIGTHWVE
Sbjct: 541 SGDHQLLCPWIGTHWVE 557
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 126 bits (316), Expect = 6e-29
Identities = 122/499 (24%), Positives = 178/499 (35%), Gaps = 23/499 (4%)
Query: 48 GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107
G +HG + SG H +H + G +HG + G +H ++
Sbjct: 705 GYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQH-ES 763
Query: 108 PSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDR 167
S +H S+ G +HG + G HG S+ +G +G +G
Sbjct: 764 RSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQ--HGSGSSQSTGFGQYGSGSGQSAGFG 821
Query: 168 THGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSR 227
HG SG H ++ S S +HG S+ G HG + + SG +H + +
Sbjct: 822 QHGSGSGQSSGFGQH-ESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQ 880
Query: 228 LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHG 287
G HG + SG HG + G H E+ S S HG S+ G HG
Sbjct: 881 YSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQH-ESRSHQSSYGQHGSGSSQSSGYGQHG 939
Query: 288 DAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG 347
+ + G H + SG HG + G H + SG H S+
Sbjct: 940 SSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNY 999
Query: 348 DRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAP 407
+ HG S+ G HG + + +G H + + SG HG + SG HG
Sbjct: 1000 GQ-HGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGS 1058
Query: 408 SPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRT 467
G + ++ SR S HG S SG HG G H SG
Sbjct: 1059 GQSSGFGQY-ESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQ 1117
Query: 468 HGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRL 527
+G + SG HG + S +H SG ++G HG S+
Sbjct: 1118 YGSGSGQSSGFGQHGSGTGKSSGFAQH----EYRSGQSSYGQ----------HGTGSSQS 1163
Query: 528 SGDRKH--GDAPSPLSGDH 544
SG +H G P+ G H
Sbjct: 1164 SGCGQHESGSGPTTSFGQH 1182
Score = 124 bits (312), Expect = 2e-28
Identities = 127/514 (24%), Positives = 172/514 (33%), Gaps = 28/514 (5%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+H S SG H + G + S G G S G G S
Sbjct: 620 QHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSS 679
Query: 111 LIGDRK----------HGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAP 160
G + HG S+ G +HG + G H + + S HG
Sbjct: 680 GFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGS 739
Query: 161 SPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRK 220
SG HG SG H ++ S S +H S+ G HG + SG +
Sbjct: 740 GQSSGFGQHGSGSGQSSGFGQH-ESRSGQSSYGQHSSGSSQSSGYGQHGSRQT--SGFGQ 796
Query: 221 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRL 280
HG S+ G +G + +G HG + G H E+ S S HG S+
Sbjct: 797 HGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQH-ESRSHQSSYGQHGSGSSQS 855
Query: 281 GGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 340
G HG + + G H + + SG HG + G HG + SG H +
Sbjct: 856 SGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQH-E 914
Query: 341 APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGD 400
+ S HG S+ G HG + + G H + SG HG + SG
Sbjct: 915 SRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGF 974
Query: 401 RTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPS 460
H G H ++ S S HG S SG HG + G H +
Sbjct: 975 GQHESGSGKSSGFGQH-ESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSG 1033
Query: 461 PLSGDRTHGDALSRLSGDRTHG------------DPLSRLSRDRKHGDAPSPLSGDCTHG 508
SG HG + SG HG + SR S +HG S SG HG
Sbjct: 1034 QYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHG 1093
Query: 509 DAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSG 542
SG H + SG ++G SG
Sbjct: 1094 SNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSG 1127
Score = 122 bits (305), Expect = 1e-27
Identities = 125/492 (25%), Positives = 178/492 (36%), Gaps = 13/492 (2%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG S SG H G +H S+ +G +HG + + G +HG +
Sbjct: 431 QHGTGLSQSSGFEQHVCGSGQTCG--QHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQ 488
Query: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170
G + G + G +HG G HG + SG H ++ S S HG
Sbjct: 489 SSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQH-ESRSRQSSYGQHG 547
Query: 171 DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGG 230
S SG +G + SG +HG + G +G + SG +HG + G
Sbjct: 548 SGSSQSSGYGQYGSRET--SGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSG 605
Query: 231 DRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAP 290
H ++ S S H S+ G HG + SG HG S+ G +G
Sbjct: 606 FGQH-ESRSGQSSYGQHSSGSSQSSGYGQHGS--RQTSGFGQHGSGSSQSTGFGQYGSGS 662
Query: 291 SRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRT 350
+ G H + SG H ++ S HG S+ SG HG + + G
Sbjct: 663 GQSSGFGQHVSGSGQSSGFGQH-ESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQ 721
Query: 351 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPL 410
H + + HG + SG HG + SG H ++ S S H S
Sbjct: 722 HELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQH-ESRSGQSSYGQHSSGSSQS 780
Query: 411 GGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGD 470
G HG + SG HG S +G +G G HG SG H +
Sbjct: 781 SGYGQHGS--RQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQH-E 837
Query: 471 ALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGD 530
+ S S HG S+ S +HG + SG H + SG HG + SG
Sbjct: 838 SRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGF 897
Query: 531 RKHGDAPSPLSG 542
+HG SG
Sbjct: 898 GQHGTGSGQYSG 909
Score = 119 bits (298), Expect = 7e-27
Identities = 125/502 (24%), Positives = 181/502 (36%), Gaps = 34/502 (6%)
Query: 65 HRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRL 124
H S +G +H + + G +HG + G + G + G +HG +
Sbjct: 456 HESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQS 515
Query: 125 IGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGD 184
G +HG G H ++ SR S HG S SG +G + SG HG
Sbjct: 516 SGFGQHGSVSGQSSGFGQH-ESRSRQSSYGQHGSGSSQSSGYGQYGSRET--SGFGQHGL 572
Query: 185 APSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGD 244
+ +G ++G + G HG + SG +H ++ S H S+ SG
Sbjct: 573 GSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQH-ESRSGQSSYGQHSSGSSQSSGY 631
Query: 245 RTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTH----------GDAPSRLG 294
HG + G HG S+ +G +G + G H G SR G
Sbjct: 632 GQHGSRQT--SGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSG 689
Query: 295 GDR--THGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHG 352
HG S+ SG HG + + G H + + S HG + G HG
Sbjct: 690 HSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHG 749
Query: 353 DAPSRLGG-----DRT-------HGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGD 400
+ G R+ H S+ SG HG + SG HG S+ +G
Sbjct: 750 SGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQT--SGFGQHGSGSSQSTGF 807
Query: 401 RTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPS 460
+G G HG + SG H ++ SH S HG S G HG +
Sbjct: 808 GQYGSGSGQSAGFGQHGSGSGQSSGFGQH-ESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 866
Query: 461 PLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTH 520
SG H + + SG HG + S +HG SG H ++ S S H
Sbjct: 867 QTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQH-ESRSHQSSYGQH 925
Query: 521 GDPLSRLSGDRKHGDAPSPLSG 542
G S+ SG +HG + G
Sbjct: 926 GSGSSQSSGYGQHGSSSGQTFG 947
Score = 112 bits (280), Expect = 9e-25
Identities = 118/465 (25%), Positives = 170/465 (36%), Gaps = 24/465 (5%)
Query: 90 KHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSR 149
++G S+ +HG S+ G +H + G +H S +G HG + +
Sbjct: 418 QYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCG--QHESTSSQSLGYDQHGSSSGK 475
Query: 150 LSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHG 209
SG HG SG G SG HG + SG +HG + G H
Sbjct: 476 TSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQH- 534
Query: 210 DAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSG 269
++ SR S +HG S+ G +G + SG HG + G +G + SG
Sbjct: 535 ESRSRQSSYGQHGSGSSQSSGYGQYGSRET--SGFGQHGLGSGQSTGFGQYGSGSGQSSG 592
Query: 270 DRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAP 329
HG + G H ++ S H S+ SG HG + G HG
Sbjct: 593 FGQHGSGSGQSSGFGQH-ESRSGQSSYGQHSSGSSQSSGYGQHGS--RQTSGFGQHGSGS 649
Query: 330 SRLSGDRTHGDAPSRLGGDRTH----------GDAPSRLGGDR--THGDAPSRLSGDRTH 377
S+ +G +G + G H G SR G HG S+ SG H
Sbjct: 650 SQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQH 709
Query: 378 GDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLS 437
G + + SG H + + S HG G HG + SG H ++ S S
Sbjct: 710 GSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQH-ESRSGQS 768
Query: 438 GDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDA 497
H S G HG + SG HG S+ +G +G + + +HG
Sbjct: 769 SYGQHSSGSSQSSGYGQHGSRQT--SGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSG 826
Query: 498 PSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSG 542
SG H ++ S S HG S+ SG +HG + SG
Sbjct: 827 SGQSSGFGQH-ESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSG 870
Score = 68.2 bits (165), Expect = 2e-11
Identities = 115/441 (26%), Positives = 157/441 (35%), Gaps = 86/441 (19%)
Query: 142 THGDAPSRLSGDRTHGDAPSPL----------SGDRTH----GDAPSPLSGDRTHGDAPS 187
THG A S+ HG++ S + +GD T G S +G RT G
Sbjct: 1748 THGQARSQ------HGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTG---R 1798
Query: 188 RLSGDRKHGDAPSRLG-GDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRT 246
R SG ++ D+ G R H + +HG++ S + D HG T
Sbjct: 1799 RSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIV--DERHGT---------T 1847
Query: 247 HGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTH-GDAPSR 305
HG G ++ G S SG T G R G D+ GG TH G S+
Sbjct: 1848 HGQTGDTSGHSQS-GHGQSTQSGSSTTG---RRRSGHSESSDSEVHSGGSHTHSGHTHSQ 1903
Query: 306 LSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLG---GDR 362
++ THG+ +GD T PS +T R G +
Sbjct: 1904 ARSQHGESESTVHKRHQTTHGQ-----TGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEY 1958
Query: 363 THGDAPSRLS---GDRTHGDAPSRL-----SGDRTHGDAPSRLSGDRTHGDA---PSPLG 411
+ + PS +S THG A S S HG + + HG + S
Sbjct: 1959 SDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQR 2018
Query: 412 GDRTHGDALSRLSGDRTHGDAPSHLSGDRTH-GDAPSPLGGDRTHGDAPSPL--SGDRTH 468
G RT G R SG + D+ H TH G A G HG++ S + TH
Sbjct: 2019 GSRTTG---RRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQ--HGESGSSVHERHGTTH 2073
Query: 469 GDALSRLSGDRT------HGDPLSRLSRDR-KHGDAPSPLSGDCTHGDAPSPLSGDRTHG 521
G +GD T HG R SR + G S S H SG T+G
Sbjct: 2074 GQ-----TGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSG-HTYG 2127
Query: 522 DPLSRLSGDRKHGDAPSPLSG 542
S +HG++ S + G
Sbjct: 2128 QARS------QHGESGSAIHG 2142
Score = 56.2 bits (134), Expect = 8e-08
Identities = 117/431 (27%), Positives = 155/431 (35%), Gaps = 83/431 (19%)
Query: 140 DRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSG--DRTHGDAPSRLS-GDRKHG 196
D T + S +S R H + HG++ S + + T+G G HG
Sbjct: 1349 DATDSEVHSGVS-HRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHG 1407
Query: 197 DAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGG-------DRTHGDAPSRL--SGDRTH 247
+ R G RT G R SG + D+ GG ++THG A S+ SG H
Sbjct: 1408 QSTQR--GSRTTG---RRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVH 1462
Query: 248 GDAPSRLG--GDRT------HGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTH 299
G + G GD T HG++ R G T G R G D+ GG TH
Sbjct: 1463 GRHGTTHGQTGDTTRHAHYHHGKSTQR--GSSTTG---RRGSGHSESSDSEVHSGGSHTH 1517
Query: 300 GDAPSRLSGDRTHGDAPSRLGGDR---THGEAPSRLSGDRTH----GDAPSRLGGDRTHG 352
SG + HG++ S + DR THG+ +GD T G + G RT G
Sbjct: 1518 SGHTHGQSGSQ-HGESESII-HDRHRITHGQ-----TGDTTRHSYSGHEQTTQTGSRTTG 1570
Query: 353 ---DAPSRLGGDRTHGDAPSR-LSGDRTHGDAPSR-----LSGDRTHGDAPSRLSGDRTH 403
+ S H R S + T+G A S+ + HG ++ H
Sbjct: 1571 RQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGH 1630
Query: 404 ---GDAPSPLGGDRTHG---DALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDR---- 453
G S G RT G + S S H SH THG A S G
Sbjct: 1631 SHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGV-SHTHTGHTHGQAGSQHGQSESIVP 1689
Query: 454 -----THGDAPSPLSGDRT----HGDALSRLSGDRT---HGDPLSRLSRDRKHGDAPSPL 501
THG +GD T + L+ +G RT G S S +
Sbjct: 1690 ERHGTTHGQ-----TGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTH 1744
Query: 502 SGDCTHGDAPS 512
SG THG A S
Sbjct: 1745 SGH-THGQARS 1754
Score = 37.0 bits (84), Expect = 0.048
Identities = 77/355 (21%), Positives = 121/355 (34%), Gaps = 37/355 (10%)
Query: 210 DAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSG 269
D P SG R + G + + SR + HG RLG + ++
Sbjct: 121 DTPGHKSGYRHSSWSE---GEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGS 177
Query: 270 DRTHGDAP---SRLGGDRTHGDAPSRLGG--DRTHGDAPSRLSGDRTHGDAPSRLGGDRT 324
+ + + S GG HG + L +++H +PSR SG+ + S +
Sbjct: 178 QKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSH-ISPSRESGEEYESGSGSNSWERKG 236
Query: 325 HGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLG--GDRTHGDAPSRLSGDRTHGDAPS 382
HG L ++ ++ G + S G G R+H S SG +A S
Sbjct: 237 HGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASS 296
Query: 383 RLSGDRTHGDA----------PSRLSGDRTHG--DAPSPLGGDRTHGDALSRLSGDRTHG 430
R G S + G + HG P G + + S+ R +G
Sbjct: 297 SCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYG 356
Query: 431 DAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSR 490
R +G P GG G + S G G + S +G +G R S
Sbjct: 357 A--------RENGQ-PQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGS-CGRFS- 405
Query: 491 DRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
+ + + S +G S + HG LS+ SG +H G H+
Sbjct: 406 ---NSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHE 457
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 111 bits (278), Expect = 2e-24
Identities = 121/503 (24%), Positives = 148/503 (29%), Gaps = 28/503 (5%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG S H S + + G +H + G KHG
Sbjct: 311 RHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGH 370
Query: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTH--GDAPSPLSGDRT 168
+HG + +HG + H A SG H G SP G R
Sbjct: 371 SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRG 430
Query: 169 HGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRL 228
G SP SG G S SG G S G H + SG +HG
Sbjct: 431 SGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS--SGFGHHESSSEHSSGYTQHGSGSGHS 488
Query: 229 GGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD----APSRLGGDR 284
G HG + S G + HG + G HG +PS G
Sbjct: 489 SGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRH 548
Query: 285 THGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSR 344
G S G +G S G G G G SR +G S
Sbjct: 549 ESGSRQSSSYGPHGYGSGRSSSRGPYESGS-----GHSSGLGHQESRSGQSSGYGQHGSS 603
Query: 345 LGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLS--GDRT 402
G THG HG + S HG + S HG S+ S G +
Sbjct: 604 SGHSSTHGQ----------HGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG 653
Query: 403 HGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPL 462
G SP G HG S HG S + HG G H
Sbjct: 654 SGSGQSPSRG--RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFG-HKSGSGQS 710
Query: 463 SGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGD 522
SG HG S SG R HG + SR +HG + S HG SG G
Sbjct: 711 SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGS 770
Query: 523 PLSRLSGDRKHGDAPSPLSGDHQ 545
+HG + S Q
Sbjct: 771 GSGHSPSRVRHGSSSGHSSSHGQ 793
Score = 108 bits (271), Expect = 1e-23
Identities = 119/514 (23%), Positives = 147/514 (28%), Gaps = 26/514 (5%)
Query: 48 GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107
G RKHG S H +H + G + G +HG +
Sbjct: 725 GYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSS 784
Query: 108 PSRLIGDRKHGDAPS--RLIGDRKHGDAPSPLIGDRT---------HGDAPSRLSGDRTH 156
+HG S G + G + G HG A S H
Sbjct: 785 SGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRH 844
Query: 157 GDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLS 216
G S H + S H A SG +HG + G G +
Sbjct: 845 GSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP 904
Query: 217 GDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDA 276
+HG R HG + SG H + + G HG S HG
Sbjct: 905 SYGRHGSGSGRSSSSGRHGSGSGQSSG-FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSR 963
Query: 277 PSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTH----GDAPSRLGGDRTHGEAPSRL 332
+ HG + HG + G H G +PS G G S
Sbjct: 964 SGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1023
Query: 333 SGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGD 392
G G S G G S G R S SG HG + S HG
Sbjct: 1024 YGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS--SGYGQHGSSSGHSSTHGQHGS 1081
Query: 393 APSRLSGDRTHGDAPSPLGGDRTHGDALSRLSG----DRTHGDAPSHLSGDRTHGDAPSP 448
+ S HG + HG S+ SG G +P H G R G SP
Sbjct: 1082 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH--GQRGSGSRQSP 1139
Query: 449 LGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHG 508
G G S SG HG L SG H + S +HG SG HG
Sbjct: 1140 SYGRHGSGSGRSSSSGQ--HGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 1197
Query: 509 DAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSG 542
S HG S +HG SG
Sbjct: 1198 SRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG 1231
Score = 108 bits (269), Expect = 2e-23
Identities = 119/506 (23%), Positives = 147/506 (29%), Gaps = 15/506 (2%)
Query: 48 GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107
G +HG SG H +HR + +HG + +G + G
Sbjct: 243 GYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSG 302
Query: 108 PSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDR 167
+ +HG +HG S + + SG H SG
Sbjct: 303 SRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYS 362
Query: 168 THGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKH--GDAP 225
HG S HG + S +HG + + H A SG +H G
Sbjct: 363 KHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQ 422
Query: 226 SRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRT 285
S G R G S SG G S G G S SG H + G
Sbjct: 423 SPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS--SGFGHHESSSEHSSGYTQ 480
Query: 286 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTH----GDA 341
HG G HG + S G + HG + G H G +
Sbjct: 481 HGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQS 540
Query: 342 PSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDR 401
PS G G S G +G S G G S G + S SG
Sbjct: 541 PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQS--SGYG 598
Query: 402 THGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLG--GDRTHGDAP 459
HG + HG + S HG S HG S G + G
Sbjct: 599 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQ 658
Query: 460 SPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRT 519
SP G HG S HG S + HG SG H SG
Sbjct: 659 SPSRG--RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSG-FGHKSGSGQSSGYSQ 715
Query: 520 HGDPLSRLSGDRKHGDAPSPLSGDHQ 545
HG S SG RKHG S Q
Sbjct: 716 HGSGSSHSSGYRKHGSRSGQSSRSEQ 741
Score = 104 bits (259), Expect = 2e-22
Identities = 116/518 (22%), Positives = 149/518 (28%), Gaps = 29/518 (5%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRD----APSRLIGDRKHGDAPSRLIGDRKHGD 106
+HG + S H +G +H +PS G G S G + G
Sbjct: 972 QHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGS 1031
Query: 107 APSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGD 166
S G + G S +G R+ S G HG + S HG S
Sbjct: 1032 GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTHGQHGSTSGQSSSC 1089
Query: 167 RTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPS 226
HG + S HG S+ SG + G + G G + +HG
Sbjct: 1090 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 1149
Query: 227 RLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTH 286
R HG SG H + + HG SG HG + H
Sbjct: 1150 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 1209
Query: 287 GDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLG 346
G + HG + SG HG S G + G S L +HG S G
Sbjct: 1210 GSSSGSSSHYGQHGSGSRQSSG---HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSG 1266
Query: 347 GDRTHGDAPSRLGGDRTHGDAPS---RLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTH 403
+ G SR G G S S HG HG + S
Sbjct: 1267 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 1326
Query: 404 GDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLS 463
G + G S+ SG HG HG HG S
Sbjct: 1327 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1386
Query: 464 GDRTHGDALS-------------RLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDA 510
HG + SG HG S +HG S HG +
Sbjct: 1387 SSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSS 1446
Query: 511 PSPLSGDRTHGDPLSRLSGDRKH----GDAPSPLSGDH 544
S HG + G +H G +PSP G H
Sbjct: 1447 SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1484
Score = 102 bits (255), Expect = 7e-22
Identities = 118/524 (22%), Positives = 151/524 (28%), Gaps = 30/524 (5%)
Query: 45 SYRGDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRD----APSRLIGDRKHGDAPSRLIG 100
S RG+R HG + S H +G +H +PS G G S
Sbjct: 1437 SSRGER-HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYS 1495
Query: 101 DRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAP 160
G S G + G + S +G R+ S G HG + S HG
Sbjct: 1496 PYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTHGQHGSTS 1553
Query: 161 SPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRK 220
S HG + S HG S+ SG + G + G G + +
Sbjct: 1554 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613
Query: 221 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRL 280
HG R HG SG H + + HG SG HG +
Sbjct: 1614 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQS 1673
Query: 281 GGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 340
HG + HG + SG HG S G + G S L +HG
Sbjct: 1674 SRGERHGSSSRSSSRYGQHGSGSRQSSG---HGRQGSGSGQSPSRGRHGSGLGHSSSHGQ 1730
Query: 341 APSRLGGDRTHGDAPSRLGGDRTHGDAPS---RLSGDRTHGDAPSRLSGDRTHGDAPSRL 397
S G + G SR G G S S HG HG +
Sbjct: 1731 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 1790
Query: 398 SGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGD 457
S G + HG S+ S G HG HG
Sbjct: 1791 STFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGS 1850
Query: 458 APSPLSGDRTHGDALS-------------RLSGDRTHGDPLSRLSRDRKHGDAPSPLSGD 504
S HG + SG HG S +HG S
Sbjct: 1851 GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 1910
Query: 505 CTHGDAPSPLSGDRTHGDPLSRLSGDRKH----GDAPSPLSGDH 544
HG + S HG + G +H G +PSP G H
Sbjct: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1954
Score = 102 bits (254), Expect = 9e-22
Identities = 118/524 (22%), Positives = 151/524 (28%), Gaps = 30/524 (5%)
Query: 45 SYRGDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRD----APSRLIGDRKHGDAPSRLIG 100
S RG++ HG + S H +G +H +PS G G S G
Sbjct: 1907 SSRGEQ-HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1965
Query: 101 DRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAP 160
G S G + G S +G R+ S G HG + S HG A
Sbjct: 1966 PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTHGQHGSAS 2023
Query: 161 SPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRK 220
S HG + S HG S+ SG + G + G G + +
Sbjct: 2024 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 2083
Query: 221 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRL 280
HG R HG SG H + + HG SG HG +
Sbjct: 2084 HGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQS 2143
Query: 281 GGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 340
HG + HG + SG HG S G + G S +HG
Sbjct: 2144 SRGERHGSSSGSSSRYGQHGSGSRQSSG---HGRQGSGSGHSPSRGRHGSGSGHSSSHGQ 2200
Query: 341 APSRLGGDRTHGDAPSRLGGDRTHGDAPS---RLSGDRTHGDAPSRLSGDRTHGDAPSRL 397
S G + G SR G G S S HG HG +
Sbjct: 2201 HGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 2260
Query: 398 SGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGD 457
S G + HG S+ S G HG HG
Sbjct: 2261 STFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGS 2320
Query: 458 APSPLSGDRTHGDALS-------------RLSGDRTHGDPLSRLSRDRKHGDAPSPLSGD 504
S HG + SG HG S +HG S
Sbjct: 2321 GSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 2380
Query: 505 CTHGDAPSPLSGDRTHGDPLSRLSGDRKH----GDAPSPLSGDH 544
HG + S HG + G +H G +PSP G H
Sbjct: 2381 ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424
Score = 102 bits (253), Expect = 1e-21
Identities = 118/534 (22%), Positives = 153/534 (28%), Gaps = 40/534 (7%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG T S H +H A G +H + G + G +
Sbjct: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQ 435
Query: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170
+HG R + G H + SG HG SG HG
Sbjct: 436 SPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG 495
Query: 171 DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGD----APSRLSGDRKHGDAPS 226
S G + S +HG + G HG +PS G + G S
Sbjct: 496 SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555
Query: 227 RLGGDRTHGDAPSRLSGDRTHGDA--------PSRLGGDRTHGEAPSRLSGDRTHGDAPS 278
G +G S G G SR G +G+ S THG S
Sbjct: 556 SSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
Query: 279 RLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTH 338
G + G + G +HG S S +G S G + G S ++
Sbjct: 616 TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSY 675
Query: 339 GDAPSRLGGDRTHGDAPSRLGGDRT--HGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSR 396
G S G ++G S G H + SG HG S SG R HG +
Sbjct: 676 GQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQ 735
Query: 397 LSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHG 456
S HG + HG + SG G H HG + HG
Sbjct: 736 SSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHG 795
Query: 457 DAPSPLS------------------------GDRTHGDALSRLSGDRTHGDPLSRLSRDR 492
S S G HG A S HG + S
Sbjct: 796 SGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSG 855
Query: 493 KHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRL--SGDRKHGDAPSPLSGDH 544
+H + S H A SG HG + G R G SP G H
Sbjct: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRH 909
Score = 100 bits (249), Expect = 4e-21
Identities = 108/513 (21%), Positives = 139/513 (27%), Gaps = 21/513 (4%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG SG H G +H +HG + +HG +
Sbjct: 1860 RHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGS 1919
Query: 111 LIGDRKHGDAPSRLIGDRKHGD----APSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGD 166
+HG + +G +HG +PSP G G S G G S G
Sbjct: 1920 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGP 1979
Query: 167 RTHGDAPSPLSGDRT-----------HGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRL 215
G S G R HG + S +HG A + HG + +
Sbjct: 1980 YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQS 2039
Query: 216 SGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 275
S +HG S+ G G + G G + HG R S HG
Sbjct: 2040 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGP 2099
Query: 276 APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGD 335
G H + + HG SG HG + HG + S
Sbjct: 2100 GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY 2159
Query: 336 RTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPS 395
HG + G G HG S HG R S + G S
Sbjct: 2160 GQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSS---SRGPYES 2216
Query: 396 RLSGDRTHGDAPSPLGGDRT---HGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGD 452
R G S G HG HG S G +
Sbjct: 2217 RSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 2276
Query: 453 RTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPS 512
HG S S G + HG S +HG S HG
Sbjct: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
Query: 513 PLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
SG H + SG +HG S Q
Sbjct: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQ 2369
Score = 99.4 bits (246), Expect = 8e-21
Identities = 104/461 (22%), Positives = 131/461 (28%), Gaps = 21/461 (4%)
Query: 103 KHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSP 162
+HG + + HG + G +H + G HG SG HG
Sbjct: 207 QHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQ 266
Query: 163 LSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHG 222
S H + S HG + G + G + HG S +HG
Sbjct: 267 SSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHG 326
Query: 223 DAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG 282
S + + SG H + G HG S HG +
Sbjct: 327 SGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASS 386
Query: 283 DRTHGDAPSRLGGDRTHGDAPSRLSGDRTH--GDAPSRLGGDRTHGEAPSRLSGDRTHGD 340
HG + + H A SG H G S G R G S SG G
Sbjct: 387 SGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGF 446
Query: 341 APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGD 400
S G G S G H + SG HG SG HG + S
Sbjct: 447 GRSSSSGPYVSGSGYS--SGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRG 504
Query: 401 RTHGDAPSPLGGDRTHGDALSRLSGDRTH----GDAPSHLSGDRTHGDAPSPLGGDRTHG 456
G + HG + G H G +PS G G S G +G
Sbjct: 505 ERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYG 564
Query: 457 DAPSPLSGDRTHGDALS-----------RLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDC 505
S G G S + SG HG S +HG S
Sbjct: 565 SGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 624
Query: 506 THGDAPSPLSGDRTHGDPLSRLS--GDRKHGDAPSPLSGDH 544
HG S HG S+ S G + G SP G H
Sbjct: 625 QHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665
Score = 99.0 bits (245), Expect = 1e-20
Identities = 104/494 (21%), Positives = 136/494 (27%), Gaps = 7/494 (1%)
Query: 45 SYRGDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKH 104
S +G +HG S H +H + + +H A G +H
Sbjct: 824 SGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRH 883
Query: 105 GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLS 164
G + G + G + +HG HG + SG H + S
Sbjct: 884 GSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSG-FGHKSSSGQSS 942
Query: 165 GDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKH--- 221
G HG S HG + S +HG + HG + G +H
Sbjct: 943 GYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1002
Query: 222 -GDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRL 280
G +PS G G S G G S G G S G R S
Sbjct: 1003 SGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS-- 1060
Query: 281 GGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 340
G HG + HG + S HG + + HG S+ SG G
Sbjct: 1061 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 1120
Query: 341 APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGD 400
+ G G + HG R S HG SG H + + S
Sbjct: 1121 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY 1180
Query: 401 RTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPS 460
HG G HG + S HG + S HG G G
Sbjct: 1181 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSG 1240
Query: 461 PLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTH 520
HG L S HG R S + S H S H
Sbjct: 1241 HSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 1300
Query: 521 GDPLSRLSGDRKHG 534
G +HG
Sbjct: 1301 GSGSGHFCSQGQHG 1314
Score = 99.0 bits (245), Expect = 1e-20
Identities = 109/497 (21%), Positives = 143/497 (28%), Gaps = 24/497 (4%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG S H G H + + G +HG +HG +
Sbjct: 2317 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 2376
Query: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170
+HG + +HG +G HG G +PSP G G
Sbjct: 2377 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS---------GQSPSPSRGRHGSG 2427
Query: 171 DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGG 230
S G S G + G S G R S SG +HG +
Sbjct: 2428 SGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS--SGYGQHGSSSGHSST 2485
Query: 231 DRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAP 290
HG + S HG + + HG S+ SG G + G G
Sbjct: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
Query: 291 SRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRT 350
+ HG R S HG G H + + S HG G
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
Query: 351 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTH----GDAPSR------LSGD 400
HG + HG + S HG + SG G +PSR L
Sbjct: 2606 HGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 2665
Query: 401 RTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPS---HLSGDRTHGDAPSPLGGDRTHGD 457
+HG S G + G SRL G S H S HG HG
Sbjct: 2666 SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 2725
Query: 458 APSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGD 517
S G + + S G S+ S +HG HG S
Sbjct: 2726 TSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSY 2785
Query: 518 RTHGDPLSRLSGDRKHG 534
HG + SG +HG
Sbjct: 2786 GQHGSGSGQSSGYSQHG 2802
Score = 98.6 bits (244), Expect = 1e-20
Identities = 99/398 (24%), Positives = 124/398 (31%), Gaps = 17/398 (4%)
Query: 151 SGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGD 210
SG S G++ S G G S G +HG + + THG
Sbjct: 166 SGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYG--QHGSGSGQSSSNDTHGS 223
Query: 211 APSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGD 270
+ SG +H + + G HG SG HG + H + S
Sbjct: 224 GSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSY 283
Query: 271 RTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPS 330
HG + G G + HG S HG S R H E+ S
Sbjct: 284 GQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSG-SSYSYSRGHYESGS 342
Query: 331 -RLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRT 389
+ SG H + G HG HG + S HG + + S
Sbjct: 343 GQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQ 402
Query: 390 HGDAPSRLSGDRTH--GDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPS 447
H A SG H G SP G R G S SG G S SG G S
Sbjct: 403 HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS 462
Query: 448 PLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTH 507
G H + SG HG SG HG + SR + G + S H
Sbjct: 463 --SGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQH 520
Query: 508 GDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
G G HG SG G +PSP G H+
Sbjct: 521 GSGSRQSLGHSRHG------SGS---GQSPSPSRGRHE 549
Score = 98.6 bits (244), Expect = 1e-20
Identities = 110/513 (21%), Positives = 144/513 (28%), Gaps = 22/513 (4%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG SG H+ G +H +HG + +HG +
Sbjct: 921 RHGSGSGQSSGFG-HKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGS 979
Query: 111 LIGDRKHGDAPSRLIGDRKHGD----APSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGD 166
+HG + +G +HG +PSP G G S G G S G
Sbjct: 980 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGP 1039
Query: 167 RTHGDAPSPLSGDRT-----------HGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRL 215
G S G R HG + S +HG + HG + +
Sbjct: 1040 YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 1099
Query: 216 SGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 275
S +HG S+ G G + G G + HG R S HG
Sbjct: 1100 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 1159
Query: 276 APSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGD 335
G H + + HG SG HG + HG + S
Sbjct: 1160 GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHY 1219
Query: 336 RTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPS 395
HG + G HG S G + G S L +HG S + G S
Sbjct: 1220 GQHGSGSRQSSG---HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYES 1276
Query: 396 RLSGDRTHGDAPSPLGGDRT---HGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGD 452
R G S G HG HG S G +
Sbjct: 1277 RSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY 1336
Query: 453 RTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPS 512
G S SG HG + HG S +HG S HG
Sbjct: 1337 GHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 1396
Query: 513 PLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
SG H + SG +HG S Q
Sbjct: 1397 QSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQ 1429
Score = 97.8 bits (242), Expect = 2e-20
Identities = 110/514 (21%), Positives = 137/514 (26%), Gaps = 19/514 (3%)
Query: 48 GDRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDA 107
G + G SP G R SP G +H R +HG G H +
Sbjct: 2056 GRQGSGSGQSPGHGQRGSGSRQSPSYG--RHGSGSGRSSSSGQHGPGLGESSGFGHHESS 2113
Query: 108 PSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDR 167
+ +HG G +HG HG + S HG SG
Sbjct: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG 2173
Query: 168 THGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSR 227
G HG S +HG R + S +H
Sbjct: 2174 RQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGH 2233
Query: 228 LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHG 287
HG HG + G + + S HG S+ G
Sbjct: 2234 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQG 2293
Query: 288 DAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG 347
+ HG S HG HG + SG H + + G
Sbjct: 2294 SGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSG 2353
Query: 348 DRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGD-- 405
HG HG + S HG + S HG + G HG
Sbjct: 2354 YTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 2413
Query: 406 --APSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRT--------- 454
+PSP G G S G S G G S G R
Sbjct: 2414 GQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGY 2473
Query: 455 --HGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTH--GDA 510
HG + S HG + S HG + S +HG S SG G
Sbjct: 2474 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 2533
Query: 511 PSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDH 544
SP G R G S G G S SG H
Sbjct: 2534 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 2567
Score = 96.3 bits (238), Expect = 7e-20
Identities = 109/513 (21%), Positives = 143/513 (27%), Gaps = 21/513 (4%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG + S H S G + + G + G + +HG R
Sbjct: 2031 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 2090
Query: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170
+HG G H + HG SG HG S HG
Sbjct: 2091 SSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2150
Query: 171 DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGG 230
+ S HG + SG + G HG S +HG R
Sbjct: 2151 SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGR--- 2207
Query: 231 DRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAP 290
+ G SR G S G + + S + G S G T
Sbjct: 2208 SSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 2267
Query: 291 SRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRT---HGEAPSRLSGDRTHGDAPSRLGG 347
S G +HG S S ++G S G + HG S HG
Sbjct: 2268 SSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 2327
Query: 348 DRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAP 407
HG + G H + + SG HG S HG + S HG +
Sbjct: 2328 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS 2387
Query: 408 SPLGGDRTHGDALSRLSGDRTHGD----APSHLSGDRTHGDAPS----PLGGDRTHGDAP 459
HG + G HG +PS G G S P G +
Sbjct: 2388 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSR 2447
Query: 460 SPLSGDRTHGDALS-------RLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPS 512
P H L + SG HG S +HG S HG +
Sbjct: 2448 GPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG 2507
Query: 513 PLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
S HG S+ SG + G G Q
Sbjct: 2508 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 2540
Score = 92.8 bits (229), Expect = 7e-19
Identities = 107/499 (21%), Positives = 136/499 (27%), Gaps = 19/499 (3%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG S H L G H + + +HG G +HG +
Sbjct: 1613 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 1672
Query: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170
+HG + +HG G G + HG S L +HG
Sbjct: 1673 SSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHG---SGLGHSSSHG 1729
Query: 171 DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRT---HGDAPSRLSGDRKHGDAPSR 227
S + G SR G S G HG +HG +
Sbjct: 1730 QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 1789
Query: 228 LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHG 287
G + + S HG S+ G + HG HG
Sbjct: 1790 SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHG 1849
Query: 288 DAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG 347
HG + SG H + + G HG S HG +
Sbjct: 1850 SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR 1909
Query: 348 DRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAP 407
HG + HG + G HG G +PS G G
Sbjct: 1910 GEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG---------SGQSPSPSRGRHGSGSGQ 1960
Query: 408 SPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRT 467
S G G S G G S G R S G HG + S
Sbjct: 1961 SSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS--SGYGQHGSSSGHSSTHGQ 2018
Query: 468 HGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTH--GDAPSPLSGDRTHGDPLS 525
HG A + S HG + S +HG S SG G SP G R G S
Sbjct: 2019 HGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 2078
Query: 526 RLSGDRKHGDAPSPLSGDH 544
G G S SG H
Sbjct: 2079 PSYGRHGSGSGRSSSSGQH 2097
Score = 92.4 bits (228), Expect = 1e-18
Identities = 100/458 (21%), Positives = 125/458 (27%), Gaps = 10/458 (2%)
Query: 92 GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLS 151
G +PSR +HG +HG +HG G H + + S
Sbjct: 1827 GQSPSR----GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
Query: 152 GDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGD- 210
G HG S HG S HG + S +HG + G HG
Sbjct: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
Query: 211 ---APSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRL 267
+PS G G S G G S G G S G R S
Sbjct: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS-- 2000
Query: 268 SGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGE 327
SG HG + HG A + HG + + S HG S+ G G
Sbjct: 2001 SGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060
Query: 328 APSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGD 387
+ G G + HG R HG SG H + + S
Sbjct: 2061 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSY 2120
Query: 388 RTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPS 447
HG SG HG HG + S HG SG G
Sbjct: 2121 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSG 2180
Query: 448 PLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTH 507
HG S HG R S + S +H S H
Sbjct: 2181 HSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 2240
Query: 508 GDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
G HG + S + G + S Q
Sbjct: 2241 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 2278
Score = 91.3 bits (225), Expect = 2e-18
Identities = 97/448 (21%), Positives = 125/448 (27%), Gaps = 8/448 (1%)
Query: 92 GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLS 151
G +PSR +HG +HG +HG G H + + S
Sbjct: 2297 GQSPSR----GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 2352
Query: 152 GDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDA 211
G HG S HG S HG + S +HG + G HG
Sbjct: 2353 GYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 2412
Query: 212 PSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDR 271
+ S G S G ++ S + G S G G SR
Sbjct: 2413 SGQ-SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS 2471
Query: 272 THGDAPSRLGGDRTHGDAPSRLGGDRT---HGDAPSRLSGDRTHGDAPSRLGGDRTHGEA 328
+G S G THG S G + HG + + S HG S+ G G
Sbjct: 2472 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 2531
Query: 329 PSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDR 388
+ G G + HG R HG SG H + + S
Sbjct: 2532 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 2591
Query: 389 THGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSP 448
HG SG HG HG + S HG SG G
Sbjct: 2592 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQ 2651
Query: 449 LGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHG 508
HG S HG R S + L S +H S HG
Sbjct: 2652 SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHG 2711
Query: 509 DAPSPLSGDRTHGDPLSRLSGDRKHGDA 536
HG + S + G +
Sbjct: 2712 SGSGHFCSQGQHGSTSGQSSTFDQEGSS 2739
Score = 90.9 bits (224), Expect = 3e-18
Identities = 103/463 (22%), Positives = 132/463 (28%), Gaps = 18/463 (3%)
Query: 90 KHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSR 149
+HG +HG +HG + G H + G HG
Sbjct: 2304 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGH 2363
Query: 150 LSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGD----APSRLGGD 205
S HG S HG + S HG + G +HG +PS G
Sbjct: 2364 SSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG- 2422
Query: 206 RTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPS 265
HG + S +G S G + G S G SR G +G+ S
Sbjct: 2423 -RHGSGSGQSSSYSPYG---SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 2478
Query: 266 RLSGDRTHGDAPSRLGGDRT---HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGD 322
THG S G + HG + + HG S+ SG G + G
Sbjct: 2479 SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH 2538
Query: 323 RTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPS 382
G + HG R HG G H + + S HG
Sbjct: 2539 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSG 2598
Query: 383 RLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTH 442
SG HG + S HG + HG + SG G H
Sbjct: 2599 HSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 2658
Query: 443 GDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLS---RLSRDRKHGDAPS 499
G S LG +HG S + G SRL G S S +HG
Sbjct: 2659 G---SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSG 2715
Query: 500 PLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSG 542
HG S G + S G S SG
Sbjct: 2716 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG 2758
Score = 90.5 bits (223), Expect = 4e-18
Identities = 100/471 (21%), Positives = 131/471 (27%), Gaps = 19/471 (4%)
Query: 92 GDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLS 151
G S+ G +HG + +HG +HG HG + S
Sbjct: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1399
Query: 152 GDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDA 211
G H + SG HG S HG + S +HG + HG
Sbjct: 1400 GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG 1459
Query: 212 PSRLSGDRKHGD----APSRLGGDRTHGDAPSRLSGDRTHGDA--------PSRLGGDRT 259
+ G +HG +PS G HG + S +G P G +
Sbjct: 1460 SRQSLGHGQHGSGSGQSPSPSRG--RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHS 1517
Query: 260 HG--EAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRT---HGDAPSRLSGDRTHGD 314
G SR +G S G THG S G + HG + + S HG
Sbjct: 1518 SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGS 1577
Query: 315 APSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGD 374
S+ G G + G G + HG R HG SG
Sbjct: 1578 GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGF 1637
Query: 375 RTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPS 434
H + + S HG SG HG HG + S HG
Sbjct: 1638 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSR 1697
Query: 435 HLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKH 494
SG G HG S HG R S + S +H
Sbjct: 1698 QSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 1757
Query: 495 GDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
S HG HG + S + G + S Q
Sbjct: 1758 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 1808
Score = 65.5 bits (158), Expect = 1e-10
Identities = 67/312 (21%), Positives = 88/312 (28%), Gaps = 6/312 (1%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSR 110
+HG + S H S G + + G + G + +HG R
Sbjct: 2501 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 2560
Query: 111 LIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHG 170
+HG G H + HG SG HG S HG
Sbjct: 2561 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2620
Query: 171 DAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGG 230
+ S HG + SG HG S G + G S L HG S G
Sbjct: 2621 SSSGSSSHYGQHGSGSRQSSG---HGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGR 2677
Query: 231 DRTHGDAPSRLSGDRTHGDAPSRLGGDRT---HGEAPSRLSGDRTHGDAPSRLGGDRTHG 287
+ G SRL G S G HG HG + G
Sbjct: 2678 SSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 2737
Query: 288 DAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG 347
+ + G S+ SG HG + HG + S HG + G
Sbjct: 2738 SSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSG 2797
Query: 348 DRTHGDAPSRLG 359
HG + G
Sbjct: 2798 YSQHGSGSGQDG 2809
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 65.1 bits (157), Expect = 2e-10
Identities = 95/404 (23%), Positives = 133/404 (32%), Gaps = 29/404 (7%)
Query: 154 RTHGDAPSPLSGDRTHGDAPSP-LSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAP 212
R H ++P S + G + SP LS + +PSRLS KH D + G R+ G
Sbjct: 242 RPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSP--KHRDEGRKTGSQRSSGSRS 299
Query: 213 SRLSGDRKHGDAPSRLGGDR----THGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLS 268
SG G +P R GG HG P +PS D+ AP+ +
Sbjct: 300 PSPSGGSGWG-SPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPA 358
Query: 269 GDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEA 328
+ ++PS + G GG R R+ AP R G R
Sbjct: 359 RGK---ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAP 415
Query: 329 PSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDR 388
P S + + S G R G +R HG R S
Sbjct: 416 PRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPG 475
Query: 389 THG--DAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAP 446
HG P S R+ G P R+ + SR + R H + S D
Sbjct: 476 AHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKD 535
Query: 447 SPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHG---DAPSPLSG 503
+ +A R++ R + +P R++ RK PSP S
Sbjct: 536 GEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEP-RRITSARKRPIPYYRPSPSSS 594
Query: 504 DC---------THGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPS 538
+H +PSP +HG SR G R +PS
Sbjct: 595 SSCLSSDYSTRSHSRSPSP---GHSHGSYSSRSHGTRSRTRSPS 635
Score = 64.7 bits (156), Expect = 2e-10
Identities = 109/433 (25%), Positives = 149/433 (34%), Gaps = 49/433 (11%)
Query: 49 DRKHGDTPSPLSGDRTHR----------------DPLSPLIGDRKHRDAPSRLIGDRKHG 92
++K T SP G R+HR D SP KHRD + R G
Sbjct: 239 EKKRPHTESP--GRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSG 296
Query: 93 DAPSRLIGDRKHGDAPSRLIGDRK----HGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPS 148
G G +P R G + HG P +PSP + D+ AP+
Sbjct: 297 SRSPSPSGGSGWG-SPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPT 355
Query: 149 RLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTH 208
+ + ++PSP S + G G R R AP R G R
Sbjct: 356 PPARGK---ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPR 412
Query: 209 GDAPSR-----LSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGD-APSRLGGDRTHGE 262
AP R LS R D+ S G G P G HG A R R
Sbjct: 413 -PAPPRGSSRSLSRARSSSDSGSGRGAPGP-GPEPGSERGHGGHGKRAKERPPRARPAST 470
Query: 263 APSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGD 322
+PS + R G P R+ G P R+ + SR + R H +PSR
Sbjct: 471 SPSPGAHGRRGG--PEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPH--SPSRSPSP 526
Query: 323 RTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPS 382
+ G H +A + R+ +P R + D+PS + R
Sbjct: 527 KKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIR----KRRRDSPSFMEPRRITSARKR 582
Query: 383 RLSGDR-THGDAPSRLSGD---RTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSG 438
+ R + + S LS D R+H +PSP +HG SR G R+ +PS
Sbjct: 583 PIPYYRPSPSSSSSCLSSDYSTRSHSRSPSP---GHSHGSYSSRSHGTRSRTRSPSRTPS 639
Query: 439 DRTHGDAPSPLGG 451
H + S GG
Sbjct: 640 PSYHSRSSSESGG 652
Score = 41.2 bits (95), Expect = 0.003
Identities = 77/306 (25%), Positives = 110/306 (35%), Gaps = 59/306 (19%)
Query: 5 RSSSSWGQRRRLEERRQIARLFLTPRFCDLSALGVLRCLVSYRGDRKHGDTPSPLSGDRT 64
R++ G+RRR RR+ +R SA R RG R+ P S
Sbjct: 378 RAAGGAGRRRRRRRRRRRSRS---------SASAPRR-----RGRRRPRPAPPRGSSRSL 423
Query: 65 HRDPLSPLIGDRKHRDAPSRLIG-DRKHGD----APSRLIGDRKHGDAPSRLIGDRKHGD 119
R S G + P G +R HG A R R +PS R+ G
Sbjct: 424 SRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGG- 482
Query: 120 APSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSP-----LSGDRT------ 168
P R G P R+ + SR + R H + SP LS D+
Sbjct: 483 -PEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRAR 541
Query: 169 HGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKH------- 221
H +A + + R+ +P R ++ D+PS + P R++ RK
Sbjct: 542 HSEAEATRARRRSRSYSPIR----KRRRDSPSFM--------EPRRITSARKRPIPYYRP 589
Query: 222 --GDAPSRLGGD---RTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDA 276
+ S L D R+H +PS +HG SR G R+ +PSR H +
Sbjct: 590 SPSSSSSCLSSDYSTRSHSRSPSP---GHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRS 646
Query: 277 PSRLGG 282
S GG
Sbjct: 647 SSESGG 652
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 62.0 bits (149), Expect = 1e-09
Identities = 106/438 (24%), Positives = 170/438 (38%), Gaps = 64/438 (14%)
Query: 51 KHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAP-- 108
+HG +P PL+ ++P++P +P+R DR +P +L +P
Sbjct: 373 RHGGSPQPLATTPLSQEPVNP-----PSEASPTR---DRSPPKSPEKLPQSSSSESSPPS 424
Query: 109 ------SRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAP-- 160
SR P+ G + + SP +R+HG R D++H P
Sbjct: 425 PQPTKVSRHASSSPESPKPAPAPGSHRE-ISSSPTSKNRSHG----RAKRDKSHSHTPSR 479
Query: 161 ------SPLSGDRTHGDAPSPLSGDRTHGDAP----SRLSGDRKHGDAPSRLGGDRT-HG 209
SP + R + +P + +P SR + +P R G R+
Sbjct: 480 RMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQR 539
Query: 210 DAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRL-- 267
SR ++ G + S G R+H +P+ + R+ P+R G R+ A R
Sbjct: 540 PGWSRSRNTQRRGRSRSARRG-RSHSRSPA--TRGRSRSRTPARRGRSRSRTPARRRSRS 596
Query: 268 ---SGDRTHGDAPSRLGGDRTHGDAPSRLG-----GDRTHGDAPSRLSGDRTHGDAPSRL 319
+ R+ P+R G R+ A R R+ +P+R SG R+ P+R
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG-RSRSRTPARR 655
Query: 320 GGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRT----HGDAPSR--LSG 373
G R+ P+R R+ P+R G R+ P+R G R+ G + SR +
Sbjct: 656 G--RSRSRTPARRG--RSRSRTPARRSG-RSRSRTPARRGRSRSRTPRRGRSRSRSLVRR 710
Query: 374 DRTHGDAPSR--LSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGD 431
R+H P R SG + SR S R+ ++ + R LS R+
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRS--K 768
Query: 432 APSHLSGDRT-HGDAPSP 448
A S LS R+ G +P P
Sbjct: 769 AKSRLSLRRSLSGSSPCP 786
Score = 50.1 bits (118), Expect = 5e-06
Identities = 90/362 (24%), Positives = 133/362 (36%), Gaps = 50/362 (13%)
Query: 148 SRLSGDRTH-----GDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRL 202
SR + +TH G +PSP SG R GDAP G T PS K +P
Sbjct: 279 SRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPG-TTSTQRPSSPETATKQPSSPYE- 336
Query: 203 GGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGE 262
D + + +P R AP+ L +R HG +P L
Sbjct: 337 -----DKDKDKKEKSATRPSPSPER-SSTGPEPPAPTPLLAER-HGGSPQPL-------- 381
Query: 263 APSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAP--------SRLSGDRTHGD 314
A + LS + + + + DR+ +P +L + +P SR +
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441
Query: 315 APSRLGGDRTHGE-APSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSG 373
P+ G +H E + S S +R+HG R D++H PSR G +P+
Sbjct: 442 KPAPAPG--SHREISSSPTSKNRSHG----RAKRDKSHSHTPSRRMG---RSRSPATAKR 492
Query: 374 DRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHG---DALSRLSGDRTHG 430
R+ P++ R+ R + G + SP R+ SR + G
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG 552
Query: 431 DAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSR 490
+ S G R+H +P+ G R+ A S RT R S RT P R SR
Sbjct: 553 RSRSARRG-RSHSRSPATRGRSRSRTPARRGRSRSRT---PARRRSRSRT---PTRRRSR 605
Query: 491 DR 492
R
Sbjct: 606 SR 607
Score = 47.4 bits (111), Expect = 4e-05
Identities = 108/447 (24%), Positives = 159/447 (35%), Gaps = 100/447 (22%)
Query: 131 GDAPSPLIGDRTHGDAP---------SRLSGDRT-------------------------- 155
G +PSP G R GDAP R S T
Sbjct: 293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP 352
Query: 156 ---------HGDAPSPLSGDRTHGDAP-----SPLSGDRTHGDAPSRLSGDRKHGDAPSR 201
AP+PL +R HG +P +PLS + + + + + DR +P +
Sbjct: 353 SPERSSTGPEPPAPTPLLAER-HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK 411
Query: 202 LGGDRTHGDAP--------SRLSGDRKHGDAPSRL-GGDRTHGDAPSRLSGDRTHGDAPS 252
L + +P SR + P+ G R +P+ S +R+HG
Sbjct: 412 LPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT--SKNRSHG---- 465
Query: 253 RLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGD----------- 301
R D++H PSR G R+ A ++ G R+ P++ G R+
Sbjct: 466 RAKRDKSHSHTPSRRMG-RSRSPATAKRG--RSRSRTPTKRGHSRSRSPQWRRSRSAQRW 522
Query: 302 APSRLSGDRTHGDAPSRLGGDRT-----HGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPS 356
SR R +P R G R+ G + S G R+H +P+ G R+ P+
Sbjct: 523 GRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRG-RSHSRSPATRG--RSRSRTPA 579
Query: 357 RLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTH 416
R G R+ A R S RT SR G + SR R SP+ R+
Sbjct: 580 RRGRSRSRTPA-RRRSRSRTPTRRRSRSRTPARRGRSRSRTPA-RRRSRTRSPV-RRRSR 636
Query: 417 GDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSG-DRTHGDALSRL 475
+ +R SG R+ P+ R+ +P R+ P+ SG R+ A
Sbjct: 637 SRSPARRSG-RSRSRTPARRGRSRSR----TPARRGRSRSRTPARRSGRSRSRTPARRGR 691
Query: 476 SGDRTHGDPLSR----LSRDRKHGDAP 498
S RT SR + R R H P
Sbjct: 692 SRSRTPRRGRSRSRSLVRRGRSHSRTP 718
Score = 37.7 bits (86), Expect = 0.028
Identities = 35/133 (26%), Positives = 51/133 (38%), Gaps = 11/133 (8%)
Query: 401 RTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTH-----GDAPSPLGGDRTH 455
R+ P+P R H + + + S + +TH G +PSP G R
Sbjct: 247 RSRSTTPAPKSR-RAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGE 305
Query: 456 GDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDA--PSPLSGDCTHG---DA 510
GDAP G + S + + P +D+K A PSP + G A
Sbjct: 306 GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA 365
Query: 511 PSPLSGDRTHGDP 523
P+PL +R G P
Sbjct: 366 PTPLLAERHGGSP 378
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 59.3 bits (142), Expect = 9e-09
Identities = 93/281 (33%), Positives = 108/281 (38%), Gaps = 45/281 (16%)
Query: 186 PSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGD----APSRLGGDRTHGDAPSRL 241
P + G G R GG R G R GD K GD PS + ++ ++
Sbjct: 319 PEFMRGGGSGGGRRGR-GGYRGRGGFQGR-GGDPKSGDWVCPNPSCGNMNFARRNSCNQC 376
Query: 242 SGDRTHGDAPSRLGGD-RTHGEAPSR-LSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTH 299
+ R PS GGD R G R G G GGDR+ G GGDR+
Sbjct: 377 NEPRPEDSRPS--GGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGG----YGGDRSS 430
Query: 300 GDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDR---THGDAPS 356
G SGDR+ G GGDR+ G GDR G GGDR GD
Sbjct: 431 GGG---YSGDRSGGG----YGGDRSGGG----YGGDRGGG-----YGGDRGGGYGGDRGG 474
Query: 357 RLGGDR--THGDAPSRLSGDR-THGDAPSRLSGDR-THGDAPSRLSGDRTHGDAPSPLGG 412
GGDR GD GDR +G GDR +G GDR+ G GG
Sbjct: 475 GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG----YGG 530
Query: 413 DRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDR 453
DR G S GDR+ G SG GD GGDR
Sbjct: 531 DRGGG---SGYGGDRSGGYGGDR-SGGGYGGDRGGGYGGDR 567
Score = 55.8 bits (133), Expect = 1e-07
Identities = 66/187 (35%), Positives = 75/187 (40%), Gaps = 31/187 (16%)
Query: 139 GDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDA 198
GDR+ G GDR+ G SGDR+ G SG GD GDR G
Sbjct: 417 GDRSGGG----YGGDRSSGGG---YSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGG-- 467
Query: 199 PSRLGGDRTHGDAPSRLSGDR--KHGDAPSRLGGDR-THGDAPSRLSGDR-THGDAPSRL 254
GGDR G GDR GD GGDR +G GDR +G
Sbjct: 468 ---YGGDRGGG-----YGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGY 519
Query: 255 GGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGD 314
GGDR+ G GDR G S GGDR+ G R GG GD GDR G
Sbjct: 520 GGDRSRG----GYGGDRGGG---SGYGGDRSGGYGGDRSGGG-YGGDRGGGYGGDR--GG 569
Query: 315 APSRLGG 321
++GG
Sbjct: 570 YGGKMGG 576
Score = 37.4 bits (85), Expect = 0.036
Identities = 48/143 (33%), Positives = 54/143 (37%), Gaps = 21/143 (14%)
Query: 399 GDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDR---TH 455
GDR+ G GGDR+ G S GDR+ G SG GD GGDR
Sbjct: 417 GDRSGGG----YGGDRSSGGGYS---GDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 469
Query: 456 GDAPSPLSGDR--THGDALSRLSGDR-THGDPLSRLSRDR-KHGDAPSPLSGDCTHGDAP 511
GD GDR GD GDR +G DR +G GD + G
Sbjct: 470 GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG-- 527
Query: 512 SPLSGDRTHGDPLSRLSGDRKHG 534
GDR G S GDR G
Sbjct: 528 --YGGDRGGG---SGYGGDRSGG 545
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 59.3 bits (142), Expect = 9e-09
Identities = 93/281 (33%), Positives = 108/281 (38%), Gaps = 45/281 (16%)
Query: 186 PSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGD----APSRLGGDRTHGDAPSRL 241
P + G G R GG R G R GD K GD PS + ++ ++
Sbjct: 322 PEFMRGGGSGGGRRGR-GGYRGRGGFQGR-GGDPKSGDWVCPNPSCGNMNFARRNSCNQC 379
Query: 242 SGDRTHGDAPSRLGGD-RTHGEAPSR-LSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTH 299
+ R PS GGD R G R G G GGDR+ G GGDR+
Sbjct: 380 NEPRPEDSRPS--GGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGG----YGGDRSS 433
Query: 300 GDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDR---THGDAPS 356
G SGDR+ G GGDR+ G GDR G GGDR GD
Sbjct: 434 GGG---YSGDRSGGG----YGGDRSGGG----YGGDRGGG-----YGGDRGGGYGGDRGG 477
Query: 357 RLGGDR--THGDAPSRLSGDR-THGDAPSRLSGDR-THGDAPSRLSGDRTHGDAPSPLGG 412
GGDR GD GDR +G GDR +G GDR+ G GG
Sbjct: 478 GYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG----YGG 533
Query: 413 DRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDR 453
DR G S GDR+ G SG GD GGDR
Sbjct: 534 DRGGG---SGYGGDRSGGYGGDR-SGGGYGGDRGGGYGGDR 570
Score = 55.8 bits (133), Expect = 1e-07
Identities = 66/187 (35%), Positives = 75/187 (40%), Gaps = 31/187 (16%)
Query: 139 GDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDA 198
GDR+ G GDR+ G SGDR+ G SG GD GDR G
Sbjct: 420 GDRSGGG----YGGDRSSGGG---YSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGG-- 470
Query: 199 PSRLGGDRTHGDAPSRLSGDR--KHGDAPSRLGGDR-THGDAPSRLSGDR-THGDAPSRL 254
GGDR G GDR GD GGDR +G GDR +G
Sbjct: 471 ---YGGDRGGG-----YGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGY 522
Query: 255 GGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGD 314
GGDR+ G GDR G S GGDR+ G R GG GD GDR G
Sbjct: 523 GGDRSRG----GYGGDRGGG---SGYGGDRSGGYGGDRSGGG-YGGDRGGGYGGDR--GG 572
Query: 315 APSRLGG 321
++GG
Sbjct: 573 YGGKMGG 579
Score = 37.4 bits (85), Expect = 0.036
Identities = 48/143 (33%), Positives = 54/143 (37%), Gaps = 21/143 (14%)
Query: 399 GDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDR---TH 455
GDR+ G GGDR+ G S GDR+ G SG GD GGDR
Sbjct: 420 GDRSGGG----YGGDRSSGGGYS---GDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYG 472
Query: 456 GDAPSPLSGDR--THGDALSRLSGDR-THGDPLSRLSRDR-KHGDAPSPLSGDCTHGDAP 511
GD GDR GD GDR +G DR +G GD + G
Sbjct: 473 GDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGG-- 530
Query: 512 SPLSGDRTHGDPLSRLSGDRKHG 534
GDR G S GDR G
Sbjct: 531 --YGGDRGGG---SGYGGDRSGG 548
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 57.8 bits (138), Expect = 3e-08
Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 8/188 (4%)
Query: 57 SPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRLIGDRK 116
SP S T D L P I D + + P D ++ + P + D + + P + D +
Sbjct: 167 SPASDSETE-DALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSE 225
Query: 117 HGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPL 176
+ P D ++ + P P I D D P + D + + P P D D P
Sbjct: 226 SEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQ 285
Query: 177 SGDRTHGDAP------SRLSGDRKHGDAPSRLGGDRTHGDAP-SRLSGDRKHGDAPSRLG 229
+ D + + P S G +K + S H P S DR++ + +
Sbjct: 286 ASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQ 345
Query: 230 GDRTHGDA 237
D H D+
Sbjct: 346 NDSFHSDS 353
Score = 57.4 bits (137), Expect = 3e-08
Identities = 38/170 (22%), Positives = 66/170 (38%), Gaps = 7/170 (4%)
Query: 49 DRKHGDTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDRKHGDAP 108
D + + P + D + +P P + D + + P + D + + P D ++ + P
Sbjct: 184 DSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELP 243
Query: 109 SRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSP-LSGDR 167
I D + D P D ++ + P P I D D P + D + + P P +S
Sbjct: 244 KPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSE 303
Query: 168 THGDAPSPLSGDRT-----HGDAP-SRLSGDRKHGDAPSRLGGDRTHGDA 211
+ G P S T H P S DR++ + + D H D+
Sbjct: 304 SEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDS 353
Score = 48.9 bits (115), Expect = 1e-05
Identities = 47/241 (19%), Positives = 82/241 (34%), Gaps = 8/241 (3%)
Query: 44 VSYRGDRKHGDTPSPLSG-DRTHRDPLSPLIGDRKHRDAPSRLIGDRKHGDAPSRLIGDR 102
V+ G + L G D + + L+ D ++ D D + + D
Sbjct: 113 VNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDS 172
Query: 103 KHGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSP 162
+ DA I D + + P D ++ + P P + D + P D + P
Sbjct: 173 ETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRH 232
Query: 163 LSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHG 222
+ D + + P P D D P + D ++ + P D D P + D ++
Sbjct: 233 QASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENE 292
Query: 223 DAPS-RLGGDRTHGDAPSRLSGDRT-----HGDAP-SRLGGDRTHGEAPSRLSGDRTHGD 275
+ P R+ + G S T H P S DR + + + D H D
Sbjct: 293 ELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSD 352
Query: 276 A 276
+
Sbjct: 353 S 353
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/236 (17%), Positives = 78/236 (33%), Gaps = 2/236 (0%)
Query: 311 THGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSR 370
+ D P L + E R + + + + + ++ G D +
Sbjct: 69 SENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKL 128
Query: 371 LSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHG 430
D + + + + D + D + D + D DAL D
Sbjct: 129 PGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESE 188
Query: 431 DAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGD-PLSRLS 489
+ P H + D + + P P D + P P D + + D + + P R+S
Sbjct: 189 EPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRIS 248
Query: 490 RDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
D + D P + D + + P P D DP + D ++ + P P D +
Sbjct: 249 -DSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSE 303
Score = 43.5 bits (101), Expect = 5e-04
Identities = 63/354 (17%), Positives = 110/354 (31%), Gaps = 14/354 (3%)
Query: 164 SGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGD 223
SGD++ +P+ +R D+ S D + S G H + + DR+ G
Sbjct: 7 SGDQSDDGGATPVQDER---DSGSDGEDDVNEQHSGSDTGSVERHSENET---SDREDG- 59
Query: 224 APSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGD 283
P + D P L+ + + R + E + + + ++ G D
Sbjct: 60 LPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSD 119
Query: 284 RTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPS 343
+ G D + + + + D + D D E + D DA
Sbjct: 120 SESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALK 179
Query: 344 RLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTH 403
D + P D + + P D + P D + P + D +
Sbjct: 180 PQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSEN 239
Query: 404 GDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSP-L 462
+ P P D D + D + + P D D P D + + P P +
Sbjct: 240 EELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRV 299
Query: 463 SGDRTHGDALSRLSGDRTHG------DPLSRLSRDRKHGDAPSPLSGDCTHGDA 510
S + G S T P S DR++ + + D H D+
Sbjct: 300 SDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDS 353
Score = 38.1 bits (87), Expect = 0.021
Identities = 41/245 (16%), Positives = 77/245 (31%), Gaps = 1/245 (0%)
Query: 298 THGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSR 357
+ D P L+ + + R + E + + + ++ G D +
Sbjct: 69 SENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKL 128
Query: 358 LGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHG 417
G D + + + + D + D + D + + D DA P D
Sbjct: 129 PGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESE 188
Query: 418 DALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSG 477
+ + D + + P D + P P D + P + D + +
Sbjct: 189 EPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRIS 248
Query: 478 DRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGD-PLSRLSGDRKHGDA 536
D DP + D ++ + P P D D P + D + + P R+S G
Sbjct: 249 DSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQ 308
Query: 537 PSPLS 541
P S
Sbjct: 309 KGPAS 313
>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sapiens]
Length = 1555
Score = 54.7 bits (130), Expect = 2e-07
Identities = 84/314 (26%), Positives = 109/314 (34%), Gaps = 22/314 (7%)
Query: 179 DRTHGDAPSRLSGDRKHGDAP-SRLGGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDA 237
DR P D+ D+P SR G T+ + L+ DR D PSR R D
Sbjct: 709 DRFPLKRPRYEDSDKPFVDSPASRFAGLDTN-QRLTALAEDRPLFDGPSRPSVAR---DG 764
Query: 238 PSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTH--GDAPSRLGG 295
P+++ + + +P R+ G T S + G P R G + G P R G
Sbjct: 765 PTKMIFEGPNKLSP-RIDGPPTPASLRFDGSPGQMGGGGPLRFEGPQGQLGGGCPLRFEG 823
Query: 296 DRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGD----RTHGDAPSRLGGDRTH 351
P R G GG R G R G R G +GG R
Sbjct: 824 PPGPVGTPLRFEGPIGQAGG----GGFRFEGSPGLRFEGSPGGLRFEGPGGQPVGGLRFE 879
Query: 352 GDAPSRLGGDR---THGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPS 408
G +GG R HG L D G L + HG + + + D HG
Sbjct: 880 GHRGQPVGGLRFEGPHGQPVGGLRFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQ--- 936
Query: 409 PLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTH 468
P GG R G L + G R G ++G R G G R G P G R
Sbjct: 937 PGGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQHNQLGGNLRFEGPHGQPGVGIRFE 996
Query: 469 GDALSRLSGDRTHG 482
G + + G R G
Sbjct: 997 GPLVQQGGGMRFEG 1010
Score = 50.4 bits (119), Expect = 4e-06
Identities = 72/270 (26%), Positives = 94/270 (34%), Gaps = 44/270 (16%)
Query: 257 DRTHGEAPSRLSGDRTHGDAP-SRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDA 315
DR + P D+ D+P SR G T+ + L DR D PSR S R D
Sbjct: 709 DRFPLKRPRYEDSDKPFVDSPASRFAGLDTN-QRLTALAEDRPLFDGPSRPSVAR---DG 764
Query: 316 PSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDR 375
P+++ E P++LS P+ L D +P ++GG P R G +
Sbjct: 765 PTKM-----IFEGPNKLSPRIDGPPTPASLRFD----GSPGQMGGG-----GPLRFEGPQ 810
Query: 376 TH--GDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAP 433
G P R G P R G GG R G R G
Sbjct: 811 GQLGGGCPLRFEGPPGPVGTPLRFEGPIGQAGG----GGFRFEGSPGLRFEGSP------ 860
Query: 434 SHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRK 493
G R G P+GG R G P+ G R G HG P+ L D
Sbjct: 861 ---GGLRFEGPGGQPVGGLRFEGHRGQPVGGLRFEGP----------HGQPVGGLRFDNP 907
Query: 494 HGDAPSPLSGDCTHGDAPSPLSGDRTHGDP 523
G L + HG + + + D HG P
Sbjct: 908 RGQPVGGLRFEGGHGPSGAAIRFDGPHGQP 937
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 53.1 bits (126), Expect = 6e-07
Identities = 122/409 (29%), Positives = 129/409 (31%), Gaps = 90/409 (22%)
Query: 65 HRDPLSPLIGD--RKHRDAPSRLIG--------DRKHGDAPSRLIGDRKHGDAPSRLIG- 113
HR +SPL+ D PS L G D PS L D PS L G
Sbjct: 103 HRPLVSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLL------SDVPSLLSGV 156
Query: 114 DRKHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSRLSG--------DRTHGDAPSPLSG 165
D PS D PSP D PS LSG D PSP S
Sbjct: 157 PSPPSDVPS------PPSDVPSP------PSDVPSLLSGVPSPPSDVPSPPSDVPSPPSD 204
Query: 166 DRTHGDAPSPLSGDRTHGDAPSRLSG-DRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDA 224
D PSP S D PS S D PS G D PS LSG
Sbjct: 205 VPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSG------V 258
Query: 225 PSRLGGDRTHGDAPSRLSG-DRTHGDAPSRLGG-DRTHGEAPSRLSG-DRTHGDAPSRLG 281
PS D PS LS D PS L G + PS LS D PS
Sbjct: 259 PSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPS--- 315
Query: 282 GDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDA 341
D P G D PS S D PS PS LS D
Sbjct: 316 ---PPSDIPLLSGVPSPPSDVPSPPS------DVPSPPSDVPLLSGVPSPLS------DV 360
Query: 342 PSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDR 401
P G D PS L +P RL +P RL D PS LSG
Sbjct: 361 PLLSGVPSPPSDVPSLL-------MSPHRLLMSHYSLVSPHRLDVPSLLSDVPSLLSG-- 411
Query: 402 THGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLG 450
PS G + + LSG PS SG PSP G
Sbjct: 412 ----VPSSPSGVPSLPSGVPILSG------VPSLPSG------VPSPSG 444
Score = 34.7 bits (78), Expect = 0.24
Identities = 65/197 (32%), Positives = 67/197 (34%), Gaps = 33/197 (16%)
Query: 366 DAPSRLSG--------DRTHGDAPSRLSGDRTHGDAPSRLSG-DRTHGDAPSPLGG-DRT 415
D PS LSG D PS LS D PS LSG D PSP
Sbjct: 120 DVPSLLSGVPSLPSDVSSPPSDVPSLLS------DVPSLLSGVPSPPSDVPSPPSDVPSP 173
Query: 416 HGDALSRLSG--------DRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRT 467
D S LSG D PS S D PSP D PSP S +
Sbjct: 174 PSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPS 233
Query: 468 HGDALSRLSG-DRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSG-DRTHGDPLS 525
+ LSG D S LS PSP S D PS LS D S
Sbjct: 234 LPSDVPSLSGVPSPPSDVPSLLS------GVPSPPSDISPPSDVPSLLSDVPSLPSDVPS 287
Query: 526 RLSG-DRKHGDAPSPLS 541
LSG D PS LS
Sbjct: 288 LLSGVPSPPSDVPSLLS 304
Score = 32.7 bits (73), Expect = 0.90
Identities = 66/214 (30%), Positives = 74/214 (34%), Gaps = 27/214 (12%)
Query: 54 DTPSPLSGDRTHRDPLSPLIGDRKHRDAPSRLIGDRKH--GDAPSRLIG-DRKHGDAPSR 110
D PS LSG + +SP D PS L+ D D PS L G D PS
Sbjct: 250 DVPSLLSGVPSPPSDISP------PSDVPS-LLSDVPSLPSDVPSLLSGVPSPPSDVPS- 301
Query: 111 LIGD--RKHGDAPSR------LIG-DRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPS 161
L+ D D PS L G D PSP D PS S PS
Sbjct: 302 LLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSP------PSDVPSPPSDVPLLSGVPS 355
Query: 162 PLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSG-DRK 220
PLS PSP S + +P RL +P RL D PS LSG
Sbjct: 356 PLSDVPLLSGVPSPPSDVPSLLMSPHRLLMSHYSLVSPHRLDVPSLLSDVPSLLSGVPSS 415
Query: 221 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRL 254
PS G PS SG + P L
Sbjct: 416 PSGVPSLPSGVPILSGVPSLPSGVPSPSGVPITL 449
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 52.4 bits (124), Expect = 1e-06
Identities = 114/429 (26%), Positives = 147/429 (34%), Gaps = 52/429 (12%)
Query: 152 GDRTHGDAPSPLSGDR--THGDAPSPLSGDRT--HGDAPSRLSGDRKHGDAPSRLGGDRT 207
G T P P G R +H + SG H S+ D G + SR +T
Sbjct: 2134 GQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKT 2193
Query: 208 H-----GDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRT---HGDAPSRLGGDRT 259
+ GD SR SG H +A S R + SG RT G + S+
Sbjct: 2194 YDKEQSGDG-SRHSGSHHH-EASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEG 2251
Query: 260 HGEAPSRLSGDRT---HGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAP 316
H E R SG + HG A + H + H SR SG TH A
Sbjct: 2252 HSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSG--TH-HAE 2308
Query: 317 SRLGGDRTHGEAPSRLSGDRTHG-----DAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRL 371
+ GG +R S HG A S HG A S + G + S+
Sbjct: 2309 NSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQA 2368
Query: 372 SGDRTHGDAPSRLSGDRTHGDA-PSRLSGDRT--------HGDAPSPLGGDRTH--GDAL 420
S H + S HG A P + S + G + S L TH ++
Sbjct: 2369 SDSEGHSE-DSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESA 2427
Query: 421 SRLSGDRTHGDAPSHLSGDR-THGDAPSPLGGDRTHGDAPSPLSGDR--THGDALSRLSG 477
+G T G SH R + + S G D HG P SG R +H + L SG
Sbjct: 2428 HGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGH-PGSSSGGRQGSHYEQLVDRSG 2486
Query: 478 --DRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGD 535
H S+ D HG + S + T D SGD SR SG R H
Sbjct: 2487 HSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQ---SGDG------SRHSGSRHHEA 2537
Query: 536 APSPLSGDH 544
+ S H
Sbjct: 2538 SSRADSSGH 2546
Score = 48.5 bits (114), Expect = 2e-05
Identities = 96/393 (24%), Positives = 128/393 (32%), Gaps = 44/393 (11%)
Query: 182 HGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRK----HGDAPSRLGGDRTHGDA 237
H S+ D G + SR +T D S G R H +A ++ R
Sbjct: 3464 HSHTTSQGRSDASRGQSGSRSASRQTRNDEQSG-DGSRHSWSHHHEASTQADSSRHSQSG 3522
Query: 238 PSRLSGDRT---HGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLG 294
+ +G RT G + S+ + H E R SG + S R P+
Sbjct: 3523 QGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHH 3582
Query: 295 GDRT---HGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTH 351
DR H SR SG TH A + GG +R S HG + H
Sbjct: 3583 EDRAGHGHSAESSRQSG--TH-HAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH 3639
Query: 352 GDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDA----P 407
S +G HG A S + G + S+ S H + S HG A
Sbjct: 3640 ----SGIG----HGQASSAVRDSGHRGSSGSQASDSEGHSE-DSDTQSVSAHGQAGPHQQ 3690
Query: 408 SPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDR--THGDA--PSPLS 463
S R S SG + +H + HG A GG + H A S S
Sbjct: 3691 SHQESTRGRSAGRSGRSGSFLY-QVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHS 3749
Query: 464 GDRTHGDALSRLSGDRTHGDPLS--RLSRDRK------HGDAPSPLSGDCTHGDAPSPLS 515
+ D + G R G S S DR H S D +HG + S +
Sbjct: 3750 ASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSA 3809
Query: 516 GDRTHGDPL----SRLSGDRKHGDAPSPLSGDH 544
T + SR SG R H + S H
Sbjct: 3810 SRETRNEEQSGDGSRHSGSRHHEASTQADSSRH 3842
Score = 46.2 bits (108), Expect = 8e-05
Identities = 114/493 (23%), Positives = 157/493 (31%), Gaps = 72/493 (14%)
Query: 104 HGDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSPLIGDRT------HGDAPSRLSGDRTHG 157
H S+ D G + SR + D S GD + H +A ++ R
Sbjct: 3464 HSHTTSQGRSDASRGQSGSRSASRQTRNDEQS---GDGSRHSWSHHHEASTQADSSRHSQ 3520
Query: 158 DAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSG 217
+G RT R G + S+ S + H + R G + S
Sbjct: 3521 SGQGQSAGPRT----------SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQ 3570
Query: 218 DRKHGDAPSRLGGDRT---HGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHG 274
R P+ DR H SR SG TH A + GG +R S HG
Sbjct: 3571 SRDGSRHPTSHHEDRAGHGHSAESSRQSG--TH-HAENSSGGQAASSHEQARSSAGERHG 3627
Query: 275 -----DAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEA- 328
A S HG A S + G + S+ S H + S HG+A
Sbjct: 3628 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSE-DSDTQSVSAHGQAG 3686
Query: 329 PSRLS-GDRTHGDAPSRLG--------------GDRTHGDAPSRLGGDR--THGDA--PS 369
P + S + T G + R G + HG A GG + H A S
Sbjct: 3687 PHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSS 3746
Query: 370 RLSGDRTHGDAPSRLSGDRTHGDAPS--RLSGDRT------HGDAPSPLGGDRTHGDALS 421
R S + D G R G S S DR+ H S D +HG + S
Sbjct: 3747 RHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGS 3806
Query: 422 RLSGDRTH-----GDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSG---DRTHGDALS 473
R + T GD H SG R H +A + R +G R G ++S
Sbjct: 3807 RSASRETRNEEQSGDGSRH-SGSR-HHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVS 3864
Query: 474 RLSGDRTHGDPLSRLSRD---RKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGD 530
+ S + + R S HG + H + + P+ S
Sbjct: 3865 QDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSST 3924
Query: 531 RKHGDAPSPLSGD 543
K S LS D
Sbjct: 3925 AKEHGHFSSLSQD 3937
>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
sapiens]
Length = 1067
Score = 48.1 bits (113), Expect = 2e-05
Identities = 62/328 (18%), Positives = 96/328 (29%), Gaps = 15/328 (4%)
Query: 183 GDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLS 242
G + SG +R GG + + R G +P+ G R
Sbjct: 566 GCSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRYG 625
Query: 243 GDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDA 302
G + + R + G +P SG + GG + + RL + G +
Sbjct: 626 GGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRS 685
Query: 303 PSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGD- 361
P SG +R GG + E + G +P GG
Sbjct: 686 PDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDHYGGGG 745
Query: 362 -----RTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTH 416
+ G P SG R G + + R + G +P+ G
Sbjct: 746 RSLDANSSGRLPDAYSGGHDSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNAYSGGHNS 805
Query: 417 GDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLS 476
G + + H + G +P+ G R S S DR+H R
Sbjct: 806 SSRNDPCRGGGRYEENRGHSLDANSGGHSPNAYSGGRD----SSSNSYDRSH-----RYG 856
Query: 477 GDRTHGDPLSRLSRDRKHGDAPSPLSGD 504
G + + R G +P SGD
Sbjct: 857 GGGHYEEYRGRSHDTHSRGRSPDAHSGD 884
Score = 44.7 bits (104), Expect = 2e-04
Identities = 65/324 (20%), Positives = 103/324 (31%), Gaps = 27/324 (8%)
Query: 157 GDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLS 216
G +P+ SG G + + R G +P G +
Sbjct: 605 GRSPNAYSGGHDSSSWSHRYGGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCYG 664
Query: 217 GDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDA 276
G ++ + RL + G +P SG +R GG + E + G +
Sbjct: 665 GGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRS 724
Query: 277 PSRLGGDRTHGDAPSRLGGD------RTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPS 330
P GG + G P SG R GG + E
Sbjct: 725 PDTYSRGHDSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSHRYGGGGRYEEYRG 784
Query: 331 RLSGDRTHGDAPSRLGG--DRTHGDAPSRLGG----DRTH-------GDAPSRLSGDRTH 377
R + G +P+ G + + + P R GG +R H G +P+ SG R
Sbjct: 785 RSLDANSGGRSPNAYSGGHNSSSRNDPCRGGGRYEENRGHSLDANSGGHSPNAYSGGRDS 844
Query: 378 G----DAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDR-THGDALSRLSGDRTHGDA 432
D R G + + R + G +P GD T + R S ++G +
Sbjct: 845 SSNSYDRSHRYGGGGHYEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRS 904
Query: 433 PSHLSG---DRTHGDAPSPLGGDR 453
+ G + G +P+ GG R
Sbjct: 905 DHYGRGGCYEEYQGRSPNAYGGGR 928
>gi|38261962 activating transcription factor 7 interacting protein
[Homo sapiens]
Length = 1270
Score = 44.3 bits (103), Expect = 3e-04
Identities = 59/179 (32%), Positives = 73/179 (40%), Gaps = 35/179 (19%)
Query: 327 EAPSRLSGDRTHGD-APSRLGGDRTHGDAPSRL--GGDRTHGDAPSR-------LSGDRT 376
E S+L + GD AP GD GD S + GD T GD S SGD T
Sbjct: 120 EPVSKLPAEPVSGDPAP----GDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDAT 175
Query: 377 HGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPS--PLGGDRTHGD--ALSRLSGDRTHGD- 431
GDAP SGD + GDA SGD T D S P D G+ + +SGD D
Sbjct: 176 SGDAP---SGDVSPGDA---TSGDATADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDI 229
Query: 432 APSHLSGDRTHGDAPS---PLGGDRTHGDAPSP-------LSGDRTHGDALSRLSGDRT 480
A S ++ AP+ P D GD S +G+ + S + DRT
Sbjct: 230 ASSEITSVDLASGAPASTDPASDDLASGDLSSSELASDDLATGELASDELTSESTFDRT 288
Score = 43.1 bits (100), Expect = 7e-04
Identities = 41/94 (43%), Positives = 47/94 (50%), Gaps = 17/94 (18%)
Query: 122 SRLIGDRKHGDAPSPLIGDRTHGDAPSRL--SGDRTHGDAPSPLSGDRTHGDAPSPLSGD 179
S+L + GD P+P GD GD S + SGD T GD P S + + DA S GD
Sbjct: 123 SKLPAEPVSGD-PAP--GDLDAGDPASGVLASGDSTSGD---PTSSEPSSSDAAS---GD 173
Query: 180 RTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPS 213
T GDAP SGD GDA S GD T D S
Sbjct: 174 ATSGDAP---SGDVSPGDATS---GDATADDLSS 201
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/108 (36%), Positives = 46/108 (42%), Gaps = 15/108 (13%)
Query: 442 HGDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRL--SGDRTHGDPLSRLSRDRKHGDAPS 499
H P P+ + P GD GD S + SGD T GDP S + DA S
Sbjct: 115 HNITPEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSS---EPSSSDAAS 171
Query: 500 PLSGDCTHGDAPS--PLSGDRTHGDPLSRLSGDRKHGDAPS--PLSGD 543
GD T GDAPS GD T GD + D GD S P+ G+
Sbjct: 172 ---GDATSGDAPSGDVSPGDATSGD---ATADDLSSGDPTSSDPIPGE 213
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/117 (38%), Positives = 53/117 (45%), Gaps = 22/117 (18%)
Query: 175 PLSGDRTHGDAPSRLSGDRKHGD-APSRLGGDRTHGDAPSRL--SGDRKHGDAPSRLGGD 231
PLS + S+L + GD AP GD GD S + SGD GD S +
Sbjct: 111 PLSPHNITPEPVSKLPAEPVSGDPAP----GDLDAGDPASGVLASGDSTSGDPTS---SE 163
Query: 232 RTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGD 288
+ DA S GD T GDAPS GD + G+A SGD T D S GD T D
Sbjct: 164 PSSSDAAS---GDATSGDAPS---GDVSPGDA---TSGDATADDLSS---GDPTSSD 208
Score = 39.3 bits (90), Expect = 0.010
Identities = 41/102 (40%), Positives = 46/102 (45%), Gaps = 23/102 (22%)
Query: 262 EAPSRLSGDRTHGD-APSRLGGDRTHGDAPSRL--GGDRTHGDAPSR-------LSGDRT 311
E S+L + GD AP GD GD S + GD T GD S SGD T
Sbjct: 120 EPVSKLPAEPVSGDPAP----GDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDAT 175
Query: 312 HGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGD 353
GDAPS GD + G+A SGD T D S GD T D
Sbjct: 176 SGDAPS---GDVSPGDA---TSGDATADDLSS---GDPTSSD 208
Score = 37.4 bits (85), Expect = 0.036
Identities = 31/72 (43%), Positives = 34/72 (47%), Gaps = 13/72 (18%)
Query: 126 GDRKHGDAPSPLI--GDRTHGDAPSR-------LSGDRTHGDAPS--PLSGDRTHGDAPS 174
GD GD S ++ GD T GD S SGD T GDAPS GD T GDA +
Sbjct: 137 GDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDVSPGDATSGDATA 196
Query: 175 P--LSGDRTHGD 184
SGD T D
Sbjct: 197 DDLSSGDPTSSD 208
>gi|22749325 zinc finger protein 48 [Homo sapiens]
Length = 618
Score = 44.3 bits (103), Expect = 3e-04
Identities = 105/379 (27%), Positives = 141/379 (37%), Gaps = 75/379 (19%)
Query: 236 DAPSRLSGDRTHGDAPSRLGG-----DRTHGEAPSRLSGDRTH-GDAPSRLGG-DRTHGD 288
D RL G+ G A S ++ + + RTH G+ P + G + GD
Sbjct: 92 DRGPRLLGEPRWGQASSDRAAVCGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGD 151
Query: 289 APSRLGGDRTH-GDAPSRLSGDRTHGDAPSRLGGDRTH-GEAPS---------RLSGD-- 335
+ +R+ RTH G+ P R R P ++ R GE P+ RLS D
Sbjct: 152 SSARIKHQRTHSGEKPYRA---RPPAQGPPKIPRSRIPAGERPTICGECGKSFRLSSDLV 208
Query: 336 ---RTH-GDAPSRLG-GDRTHGDAPSRLGGDRTH-GDAPSRLSGDRTHGDAPSRLSGDRT 389
RTH G+ P + G + GD+ +R+ RTH G+ P R R PSR + T
Sbjct: 209 KHQRTHTGEKPYKCGICGKGFGDSSARIKHQRTHRGEQPPRPVVPRRQ---PSRAATAAT 265
Query: 390 HG----DAP--------------SRLSGDRTHGDAPSPLGGDRTHGDALSRLSGD----R 427
G D P S LS R+H P P G D G +R S R
Sbjct: 266 QGPKAQDKPYICTDCGKRFVLSCSLLSHQRSHL-GPKPFGCD-VCGKEFARGSDLVKHLR 323
Query: 428 THGDAPSHLSGDRTHG--DAPSPLGGDRTH-GDAPSPLSG-DRTHGDALSRLSGDRTH-- 481
H +L + G D+ + + RTH G+ P DRT + + L TH
Sbjct: 324 VHTGEKPYLCPECGKGFADSSARVKHLRTHSGERPHACPECDRTFSLSSTLLRHRLTHME 383
Query: 482 -------GDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDP-LSRLSGDRKH 533
G PL L P P G SP G P L G +
Sbjct: 384 PQDFSFPGYPLPALIPS-----PPPPPLGTSPPLTPRSPSHSGEPFGLPGLEPEPGGPQA 438
Query: 534 GDAPSPLSGDHQLLCPWIG 552
G+ P PL+GD CP G
Sbjct: 439 GEPPPPLAGDKPHKCPECG 457
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 42.7 bits (99), Expect = 9e-04
Identities = 56/316 (17%), Positives = 95/316 (30%), Gaps = 26/316 (8%)
Query: 153 DRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAP 212
D+ G+ P G++ + D + R G +K + GG+ HG+
Sbjct: 680 DKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGE 739
Query: 213 SRLSGDR-----KHGDAPSRLGGDRTHGDAP----SRLSGDRTHGDAPSRLGGDRTHGEA 263
GDR K G+ G+ G+ R +R + GD+ GE
Sbjct: 740 EE-EGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEE 798
Query: 264 PSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLG-GD 322
+ T G + G G G+R + G+ G+ G G+
Sbjct: 799 ------EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG--EGEEEEGEGEEEEGEGE 850
Query: 323 RTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPS 382
GE G+ G+ G G+ G G+ G+
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEG--EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG 908
Query: 383 RLSGDRTHGDAPSRLSGDRTHGDAPSPLG-GDRTHGDALSRLSGDRTHGDAPSHLSGDRT 441
G+ G+ G+ G+ G G+ G+ G+ G+
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEG----EGEEEEGEWEGEEEEGEG 964
Query: 442 HGDAPSPLGGDRTHGD 457
G+ G+ G+
Sbjct: 965 EGEEEGEGEGEEGEGE 980
>gi|22027597 alpha 1 type XIII collagen isoform 13 [Homo sapiens]
Length = 690
Score = 42.0 bits (97), Expect = 0.001
Identities = 105/435 (24%), Positives = 132/435 (30%), Gaps = 53/435 (12%)
Query: 133 APSPLIGDRTHGDAPSRLSGDRTHGD-APSPLSGDRTHGDAPSPLSGDRTHGDAPSR--- 188
AP P+I RT S+ S G P SG H P P+ G +
Sbjct: 249 APPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDP 308
Query: 189 -------LSGDRKHGDAPSRLGGDRTHGDAPSRLSGD--------RKHGDA----PSRLG 229
G+R P + G G A + + G+ K + P LG
Sbjct: 309 GIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLG 368
Query: 230 GDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEA-------PSRLSGDRTHGDAPSRLGG 282
GDA + + G R P G GEA P GD+ A G
Sbjct: 369 QKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGP 428
Query: 283 DRTHGDAPSRLGGDRT--HGDAPSRLSGDRTHG-DAPSRLGGDRTHGEAPSRLSGDRTHG 339
D G G+ +G+ L RT P L G AP + G +
Sbjct: 429 DGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPG-IPGQKGEI 487
Query: 340 DAPSRLGGDRTHG--DAPSRLGGDRTHG----DAPSRLSGDRTHGDAPSRLSGDRTHGDA 393
P G D G P +G G D P + G+ H +P G A
Sbjct: 488 GLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQA 547
Query: 394 PSRLSGDRTHGDAPSPLGGDRTHGD----ALSRLSGDR----THGD-APSHLSGDRTHGD 444
S + G P P G G L G++ GD P L G
Sbjct: 548 GSPVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPIG 607
Query: 445 APSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGD 504
P P G G P T L L G GD +R R +K P GD
Sbjct: 608 VPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHG--PPGDKGNRGERGKKGSRGPKGDKGD 665
Query: 505 --CTHGDAPSPLSGD 517
DAP PL D
Sbjct: 666 QGAPGLDAPCPLGED 680
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 41.6 bits (96), Expect = 0.002
Identities = 82/317 (25%), Positives = 92/317 (29%), Gaps = 62/317 (19%)
Query: 131 GDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLS 190
G P P HG P G R G P P GD P+ G G P
Sbjct: 649 GPMPGP------HG-GPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRG-GPGPGP 700
Query: 191 GDRKHGDAPSRLGGDRTHGDAPSR-LSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTH-- 247
G G R G + P R G R G P+ GG G G R H
Sbjct: 701 GPYHRGRG-GRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGP---GGGMVGGGGHRPHEG 756
Query: 248 -GDAPSRLGGDRTH-GEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSR 305
G G R H G SG R H +GG GG R H
Sbjct: 757 PGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGG----------GGHRPHEGPGGG 806
Query: 306 LSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHG 365
+SG H GG G G R H +GG GG R H
Sbjct: 807 ISGGSGHRPHEGPGGGMGAGG-------GHRPHEGPGGSMGGS----------GGHRPH- 848
Query: 366 DAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSG 425
+ P HG HG P + G R H P R H G
Sbjct: 849 EGPG-------HGGP---------HGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGG 892
Query: 426 DRTHGDAPSHLSGDRTH 442
R H SH GD ++
Sbjct: 893 HRGHDGGHSH-GGDMSN 908
>gi|9955931 acrosomal vesicle protein 1 isoform d precursor [Homo
sapiens]
Length = 195
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 14/105 (13%)
Query: 228 LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAP-SRL-GGDRT 285
LG R P+ LSG H + +L G++ GE P SG+ G+ P S L G++
Sbjct: 13 LGSARGTSSQPNELSGSIDHQTSVQQLPGEQPSGEQP---SGEHLSGEQPLSELESGEQP 69
Query: 286 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPS 330
+ PS G+ G+ P SG++ G+ PS G+ GE S
Sbjct: 70 SDEQPS---GEHGSGEQP---SGEQASGEQPS---GEHASGEQAS 105
>gi|9955941 acrosomal vesicle protein 1 isoform h precursor [Homo
sapiens]
Length = 155
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 14/105 (13%)
Query: 228 LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAP-SRL-GGDRT 285
LG R P+ LSG H + +L G++ GE P SG+ G+ P S L G++
Sbjct: 13 LGSARGTSSQPNELSGSIDHQTSVQQLPGEQPSGEQP---SGEHLSGEQPLSELESGEQP 69
Query: 286 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPS 330
+ PS G+ G+ P SG++ G+ PS G+ GE S
Sbjct: 70 SDEQPS---GEHGSGEQP---SGEQASGEQPS---GEHASGEQAS 105
>gi|169213237 PREDICTED: hypothetical protein [Homo sapiens]
Length = 240
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/152 (29%), Positives = 52/152 (34%), Gaps = 28/152 (18%)
Query: 314 DAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSG 373
D S GG G++ SGD D L D GD GG GD+ SG
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQD-FRGDH----GGSDIQGDSSQEFSG 62
Query: 374 DRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDR----TH 429
D HG G GD GD GG GD+ SGD
Sbjct: 63 D--HG-------GSDIQGDLSQDFRGDH---------GGSDIQGDSSQEFSGDHGGSDIQ 104
Query: 430 GDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSP 461
GD+ SGD G P G + T+ A P
Sbjct: 105 GDSSQDFSGDWERG-GPRNKGLEVTNPRAARP 135
Score = 38.9 bits (89), Expect = 0.013
Identities = 39/130 (30%), Positives = 45/130 (34%), Gaps = 19/130 (14%)
Query: 145 DAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGG 204
D S G GD+ SGD D LS D GD G GD+ G
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQD-FRGDH----GGSDIQGDSSQEFSG 62
Query: 205 DRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAP 264
D D LS D + GD GG GD+ SGD GG G++
Sbjct: 63 DHGGSDIQGDLSQDFR-GDH----GGSDIQGDSSQEFSGDH---------GGSDIQGDSS 108
Query: 265 SRLSGDRTHG 274
SGD G
Sbjct: 109 QDFSGDWERG 118
Score = 38.1 bits (87), Expect = 0.021
Identities = 40/134 (29%), Positives = 48/134 (35%), Gaps = 30/134 (22%)
Query: 405 DAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSG 464
D S GG GD+ SGD HG G GD GD HG G
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGD--HG-------GSDIQGDLSQDFRGD--HG-------G 49
Query: 465 DRTHGDALSRLSGDRTHGDPLSRLSRDRK--------HGDAPSPLSGD----CTHGDAPS 512
GD+ SGD D LS+D + GD+ SGD GD+
Sbjct: 50 SDIQGDSSQEFSGDHGGSDIQGDLSQDFRGDHGGSDIQGDSSQEFSGDHGGSDIQGDSSQ 109
Query: 513 PLSGDRTHGDPLSR 526
SGD G P ++
Sbjct: 110 DFSGDWERGGPRNK 123
Score = 37.7 bits (86), Expect = 0.028
Identities = 40/142 (28%), Positives = 46/142 (32%), Gaps = 27/142 (19%)
Query: 197 DAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRL--------GGDRTHGDAPSRLSGDRTHG 248
D S GG GD+ SGD D L GG GD+ SGD
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQDFRGDHGGSDIQGDSSQEFSGDHGGS 67
Query: 249 DAPSRLGGD--RTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRL 306
D L D HG G GD+ GD GG GD+
Sbjct: 68 DIQGDLSQDFRGDHG-------GSDIQGDSSQEFSGDH---------GGSDIQGDSSQDF 111
Query: 307 SGDRTHGDAPSRLGGDRTHGEA 328
SGD G P G + T+ A
Sbjct: 112 SGDWERG-GPRNKGLEVTNPRA 132
Score = 37.7 bits (86), Expect = 0.028
Identities = 40/143 (27%), Positives = 46/143 (32%), Gaps = 32/143 (22%)
Query: 249 DAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSG 308
D S GG G++ SGD D L D GD GG GD+ SG
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQD-FRGDH----GGSDIQGDSSQEFSG 62
Query: 309 DRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAP 368
D GG G+ GD GG GD+ GD HG
Sbjct: 63 DH---------GGSDIQGDLSQDFRGDH---------GGSDIQGDSSQEFSGD--HG--- 99
Query: 369 SRLSGDRTHGDAPSRLSGDRTHG 391
G GD+ SGD G
Sbjct: 100 ----GSDIQGDSSQDFSGDWERG 118
Score = 34.7 bits (78), Expect = 0.24
Identities = 36/125 (28%), Positives = 42/125 (33%), Gaps = 23/125 (18%)
Query: 100 GDRKHGDAPSRLIGDRKHGDAPSRLIGDRK--HGDAPSPLIGDRTHGDAPSRLSGDRTHG 157
G GD+ GD D L D + HG G GD+ SGD
Sbjct: 15 GSDIQGDSSLDFSGDHGGSDIQGDLSQDFRGDHG-------GSDIQGDSSQEFSGDHGGS 67
Query: 158 DAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSG 217
D LS D GD G GD+ SGD GG GD+ SG
Sbjct: 68 DIQGDLSQD-FRGDH----GGSDIQGDSSQEFSGDH---------GGSDIQGDSSQDFSG 113
Query: 218 DRKHG 222
D + G
Sbjct: 114 DWERG 118
Score = 32.3 bits (72), Expect = 1.2
Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 13/96 (13%)
Query: 457 DAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSG 516
D S G GD+ SGD D LS+D + GD G GD+ SG
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQDFR-GDH----GGSDIQGDSSQEFSG 62
Query: 517 DRTHGDPLSRLSGDRK--------HGDAPSPLSGDH 544
D D LS D + GD+ SGDH
Sbjct: 63 DHGGSDIQGDLSQDFRGDHGGSDIQGDSSQEFSGDH 98
>gi|169212746 PREDICTED: hypothetical protein [Homo sapiens]
Length = 240
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/152 (29%), Positives = 52/152 (34%), Gaps = 28/152 (18%)
Query: 314 DAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSG 373
D S GG G++ SGD D L D GD GG GD+ SG
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQD-FRGDH----GGSDIQGDSSQEFSG 62
Query: 374 DRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDALSRLSGDR----TH 429
D HG G GD GD GG GD+ SGD
Sbjct: 63 D--HG-------GSDIQGDLSQDFRGDH---------GGSDIQGDSSQEFSGDHGGSDIQ 104
Query: 430 GDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSP 461
GD+ SGD G P G + T+ A P
Sbjct: 105 GDSSQDFSGDWERG-GPRNKGLEVTNPRAARP 135
Score = 38.9 bits (89), Expect = 0.013
Identities = 39/130 (30%), Positives = 45/130 (34%), Gaps = 19/130 (14%)
Query: 145 DAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGG 204
D S G GD+ SGD D LS D GD G GD+ G
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQD-FRGDH----GGSDIQGDSSQEFSG 62
Query: 205 DRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAP 264
D D LS D + GD GG GD+ SGD GG G++
Sbjct: 63 DHGGSDIQGDLSQDFR-GDH----GGSDIQGDSSQEFSGDH---------GGSDIQGDSS 108
Query: 265 SRLSGDRTHG 274
SGD G
Sbjct: 109 QDFSGDWERG 118
Score = 38.1 bits (87), Expect = 0.021
Identities = 40/134 (29%), Positives = 48/134 (35%), Gaps = 30/134 (22%)
Query: 405 DAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSG 464
D S GG GD+ SGD HG G GD GD HG G
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGD--HG-------GSDIQGDLSQDFRGD--HG-------G 49
Query: 465 DRTHGDALSRLSGDRTHGDPLSRLSRDRK--------HGDAPSPLSGD----CTHGDAPS 512
GD+ SGD D LS+D + GD+ SGD GD+
Sbjct: 50 SDIQGDSSQEFSGDHGGSDIQGDLSQDFRGDHGGSDIQGDSSQEFSGDHGGSDIQGDSSQ 109
Query: 513 PLSGDRTHGDPLSR 526
SGD G P ++
Sbjct: 110 DFSGDWERGGPRNK 123
Score = 37.7 bits (86), Expect = 0.028
Identities = 40/142 (28%), Positives = 46/142 (32%), Gaps = 27/142 (19%)
Query: 197 DAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRL--------GGDRTHGDAPSRLSGDRTHG 248
D S GG GD+ SGD D L GG GD+ SGD
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQDFRGDHGGSDIQGDSSQEFSGDHGGS 67
Query: 249 DAPSRLGGD--RTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRL 306
D L D HG G GD+ GD GG GD+
Sbjct: 68 DIQGDLSQDFRGDHG-------GSDIQGDSSQEFSGDH---------GGSDIQGDSSQDF 111
Query: 307 SGDRTHGDAPSRLGGDRTHGEA 328
SGD G P G + T+ A
Sbjct: 112 SGDWERG-GPRNKGLEVTNPRA 132
Score = 37.7 bits (86), Expect = 0.028
Identities = 40/143 (27%), Positives = 46/143 (32%), Gaps = 32/143 (22%)
Query: 249 DAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSG 308
D S GG G++ SGD D L D GD GG GD+ SG
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQD-FRGDH----GGSDIQGDSSQEFSG 62
Query: 309 DRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAP 368
D GG G+ GD GG GD+ GD HG
Sbjct: 63 DH---------GGSDIQGDLSQDFRGDH---------GGSDIQGDSSQEFSGD--HG--- 99
Query: 369 SRLSGDRTHGDAPSRLSGDRTHG 391
G GD+ SGD G
Sbjct: 100 ----GSDIQGDSSQDFSGDWERG 118
Score = 34.7 bits (78), Expect = 0.24
Identities = 36/125 (28%), Positives = 42/125 (33%), Gaps = 23/125 (18%)
Query: 100 GDRKHGDAPSRLIGDRKHGDAPSRLIGDRK--HGDAPSPLIGDRTHGDAPSRLSGDRTHG 157
G GD+ GD D L D + HG G GD+ SGD
Sbjct: 15 GSDIQGDSSLDFSGDHGGSDIQGDLSQDFRGDHG-------GSDIQGDSSQEFSGDHGGS 67
Query: 158 DAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSG 217
D LS D GD G GD+ SGD GG GD+ SG
Sbjct: 68 DIQGDLSQD-FRGDH----GGSDIQGDSSQEFSGDH---------GGSDIQGDSSQDFSG 113
Query: 218 DRKHG 222
D + G
Sbjct: 114 DWERG 118
Score = 32.3 bits (72), Expect = 1.2
Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 13/96 (13%)
Query: 457 DAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSG 516
D S G GD+ SGD D LS+D + GD G GD+ SG
Sbjct: 8 DFSSDHGGSDIQGDSSLDFSGDHGGSDIQGDLSQDFR-GDH----GGSDIQGDSSQEFSG 62
Query: 517 DRTHGDPLSRLSGDRK--------HGDAPSPLSGDH 544
D D LS D + GD+ SGDH
Sbjct: 63 DHGGSDIQGDLSQDFRGDHGGSDIQGDSSQEFSGDH 98
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 39.7 bits (91), Expect = 0.007
Identities = 80/355 (22%), Positives = 113/355 (31%), Gaps = 46/355 (12%)
Query: 167 RTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPS 226
R +P+P P+R R+ R G + +A S SG + AP+
Sbjct: 495 RQRSPSPAPAPAPAAAAGPPTRKKSRRER----KRSGEAK---EAASSSSGTQPAPPAPA 547
Query: 227 RLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTH 286
+ D+ S DR G S R+ + SR + R+ R GG R
Sbjct: 548 ------SPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRS-TDRRRGGSRRS 600
Query: 287 GDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLG 346
R R+ P+ S + + G R G + + R+ G+ S G
Sbjct: 601 RSREKRRRRRRSASPPPATSSSSSSRRER--HRGKHRDGGGSKKKKKRSRSRGEKRSGDG 658
Query: 347 GDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGD--------APSRLS 398
++ AP G + GD SR G P + D T D RL
Sbjct: 659 SEKAPAPAPPP-SGSTSCGDRDSR-----RRGAVPPSIQ-DLTDHDLFAIKRTITVGRLD 711
Query: 399 GDRTHGDAPSPLGGDRTHGDALSRLSGDRTHGDAPSHLSGDRTHGDAPSPLGGDRTHGDA 458
G +P+P + + L G LSG+ G + DR A
Sbjct: 712 KSDPRGPSPAPASSPKR--EVLYDSEG----------LSGEERGGKSSQK---DRRRSGA 756
Query: 459 PSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSP 513
S S R G L G D RDR A P + G P P
Sbjct: 757 ASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKP 811
>gi|22027595 alpha 1 type XIII collagen isoform 12 [Homo sapiens]
Length = 691
Score = 39.7 bits (91), Expect = 0.007
Identities = 105/436 (24%), Positives = 136/436 (31%), Gaps = 54/436 (12%)
Query: 133 APSPLIGDRTHGDAPSRLSGDRTHGD-APSPLSGDRTHGDAPSPLSGDRTHGDAPSR--- 188
AP P+I RT S+ S G P SG H P P+ G +
Sbjct: 249 APPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDP 308
Query: 189 -------LSGDRKHGDAPSRLGGDRTHGDAPSRLSGD--------RKHGDA----PSRLG 229
G+R P + G G A + + G+ K + P LG
Sbjct: 309 GIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLG 368
Query: 230 GDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEA-------PSRLSGDRTHGDAPSRLGG 282
GDA + + G R P G GEA P GD+ A G
Sbjct: 369 QKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGP 428
Query: 283 DRTHGDAPSRLGGDRT--HGDAPSRLSGDRTHG-DAPSRLGGDRTHGEAPSRLSGDRTHG 339
D G G+ +G+ L RT P L G AP + G +
Sbjct: 429 DGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPG-IPGQKGEI 487
Query: 340 DAPSRLGGDRTHG--DAPSRLGGDRTHG----DAPSRLSGDRTHGDAPSRLSGDRTHGDA 393
P G D G P +G G D P + G+ H +P G A
Sbjct: 488 GLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQA 547
Query: 394 PS----RLSGDRTHGDAPSPLGGDRTHGDA-LSRLSGDR----THGD-APSHLSGDRTHG 443
S +G++ + A G G+A L G++ GD P L G
Sbjct: 548 GSPGEKGEAGEKGNPGAEGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPI 607
Query: 444 DAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSG 503
P P G G P T L L G GD +R R +K P G
Sbjct: 608 GVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHG--PPGDKGNRGERGKKGSRGPKGDKG 665
Query: 504 D--CTHGDAPSPLSGD 517
D DAP PL D
Sbjct: 666 DQGAPGLDAPCPLGED 681
>gi|22027601 alpha 1 type XIII collagen isoform 15 [Homo sapiens]
Length = 668
Score = 39.3 bits (90), Expect = 0.010
Identities = 99/410 (24%), Positives = 124/410 (30%), Gaps = 45/410 (10%)
Query: 147 PSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDR 206
P SG H P P+ G P P G + G+R P + G
Sbjct: 255 PPGPSGPLGHPGLPGPMGPPGLPGP-PGPKGDPGIQGYHGRK--GERGMPGMPGKHGAKG 311
Query: 207 THGDAPSRLSGD--------RKHGDA----PSRLGGDRTHGDAPSRLSGDRTHGDAPSRL 254
G A + + G+ K + P LG GDA + + G R P
Sbjct: 312 APGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLP 371
Query: 255 GGDRTHGEA-------PSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRT--HGDAPSR 305
G GEA P GD+ A G D G G+ +G+
Sbjct: 372 GPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEA 431
Query: 306 LSGDRTHG-DAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHG--DAPSRLGGDR 362
L RT P L G AP + G + P G D G P +G
Sbjct: 432 LQEIRTLALMGPPGLPGQIGPPGAPG-IPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPG 490
Query: 363 THG----DAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGD 418
G D P + G+ H +P G A S + G P P G G
Sbjct: 491 PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGP 550
Query: 419 ----ALSRLSGDR----THGD-APSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDRTHG 469
L G++ GD P L G P P G G P T
Sbjct: 551 KGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGA 610
Query: 470 DALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLSGD--CTHGDAPSPLSGD 517
L L G GD +R R +K P GD DAP PL D
Sbjct: 611 AGLPGLHG--PPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPCPLGED 658
>gi|9955933 acrosomal vesicle protein 1 isoform e precursor [Homo
sapiens]
Length = 176
Score = 39.3 bits (90), Expect = 0.010
Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 11/92 (11%)
Query: 228 LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAP-SRL-GGDRT 285
LG R P+ LSG H + +L G++ GE P SG+ G+ P S L G++
Sbjct: 13 LGSARGTSSQPNELSGSIDHQTSVQQLPGEQPSGEQP---SGEHLSGEQPLSELESGEQP 69
Query: 286 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPS 317
+ PS G+ G+ P SG++ G+ PS
Sbjct: 70 SDEQPS---GEHGSGEQP---SGEQASGEQPS 95
Score = 39.3 bits (90), Expect = 0.010
Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 11/92 (11%)
Query: 293 LGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAP-SRL-GGDRT 350
LG R P+ LSG H + +L G++ GE P SG+ G+ P S L G++
Sbjct: 13 LGSARGTSSQPNELSGSIDHQTSVQQLPGEQPSGEQP---SGEHLSGEQPLSELESGEQP 69
Query: 351 HGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPS 382
+ PS G+ G+ P SG++ G+ PS
Sbjct: 70 SDEQPS---GEHGSGEQP---SGEQASGEQPS 95
>gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
sapiens]
Length = 351
Score = 38.9 bits (89), Expect = 0.013
Identities = 76/302 (25%), Positives = 104/302 (34%), Gaps = 40/302 (13%)
Query: 79 RDAPSRLIGDRKHGDAPSRLIGDRKHGDAPSRL----IGDRKHGDAPSRLIGDRKHGDAP 134
R P L+G+ A GDA L + R G P + R H P
Sbjct: 10 RGGPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATL--RSHPITP 67
Query: 135 SPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRK 194
+P + +H R S T A SP G P + AP R
Sbjct: 68 APALLLLSHSLPAQRRSMQATVAKAGSPGRGRL----GKEPRRRESWTRSAPRRCP---- 119
Query: 195 HGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLG--GDRTHGDAPSRLSGDRTHGDAPS 252
+ DA SR G +R GD+K P R G ++ G + G + G
Sbjct: 120 YQDA-SRAGSRVCRSRPQNRGGGDKK----PRRRGQKAAKSRGGGGKKPRGQKAAGAGAK 174
Query: 253 RLGGDRTHGEAPSRLSGDRTH--GDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDR 310
+ R GE + G + A SR GG G + GG + P R G +
Sbjct: 175 KHRKPRRRGERAAAAGGKKLQKAAAAKSRGGG----GKKTAAAGGKK-----PRRRRGQK 225
Query: 311 THGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG--DRTHGDAPSRLGGDRTHGDAP 368
A SR GGD+ + L+G ++ GD GG R G GG G+ P
Sbjct: 226 A---AKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGG---GEKP 279
Query: 369 SR 370
+
Sbjct: 280 QK 281
Score = 35.8 bits (81), Expect = 0.11
Identities = 42/168 (25%), Positives = 63/168 (37%), Gaps = 11/168 (6%)
Query: 253 RLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTH 312
RLG + E+ +R + R SR G +R GGD+ + + R
Sbjct: 99 RLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGG 158
Query: 313 GDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTH--GDAPSRLGGDR----THGD 366
G R G + G + R G+ + GG + A SR GG + G
Sbjct: 159 GGKKPR--GQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGK 216
Query: 367 APSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDR 414
P R G + A SR GD+ + L+G ++ GD GG +
Sbjct: 217 KPRRRRGQKA---AKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKK 261
Score = 33.1 bits (74), Expect = 0.69
Identities = 41/160 (25%), Positives = 60/160 (37%), Gaps = 22/160 (13%)
Query: 180 RTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDR--KHGDAPSRLGGDR----T 233
++ G + G + G + R G+ + G + K A SR GG +
Sbjct: 154 KSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAA 213
Query: 234 HGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG--DRTHGDAPS 291
G P R G + A SR GGD+ + L+G ++ GD GG R G
Sbjct: 214 GGKKPRRRRGQKA---AKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTK 270
Query: 292 RLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSR 331
GG G+ P + + A SR G GE P +
Sbjct: 271 SRGGG---GEKPQKAAA----AGAKSRGG----RGEKPQK 299
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 37.7 bits (86), Expect = 0.028
Identities = 56/220 (25%), Positives = 76/220 (34%), Gaps = 25/220 (11%)
Query: 256 GDRTHGEAPSRLSGDRTHGDAPS-RLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGD 314
G R + R D GD+ + GG +T A G G + S + D
Sbjct: 448 GARVADKVRKRRKVDEGAGDSAAVASGGAQTLALA----GSPAPSGHPKAGHSENGVEED 503
Query: 315 APSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGD 374
R G +PS T G +P+ GD ++PS G R G A GD
Sbjct: 504 TEGRTGPKEGTPGSPSE-----TPGPSPAGPAGDEP-AESPSETPGPRPAGPA-----GD 552
Query: 375 RTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTH-GDALSRLSGDRTHG--- 430
++PS G R G A + + PSP G R ++ S G R G
Sbjct: 553 EP-AESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAG 611
Query: 431 ----DAPSHLSGDRTHGDAPSPLGGDRTHGDAPSPLSGDR 466
++PS G R G A + PSP R
Sbjct: 612 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR 651
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 37.4 bits (85), Expect = 0.036
Identities = 46/214 (21%), Positives = 73/214 (34%), Gaps = 33/214 (15%)
Query: 144 GDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSR-- 201
G+ P R P P G+++ G P P + ++ G H P R
Sbjct: 44 GNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPP 103
Query: 202 -LGGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTH 260
GG+++ G P +R P GG+++H P +R P GG+++
Sbjct: 104 PQGGNQSQGTPPPPGKPER-----PPPQGGNQSHRPPPPPGKPER-----PPPQGGNQSQ 153
Query: 261 GEAPSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHG------- 313
G P + G P R+ P + G P + G++ G
Sbjct: 154 GPPP---HPGKPEGPPPQEGNKSRSARSPPGKPQG-------PPQQEGNKPQGPPPPGKP 203
Query: 314 DAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGG 347
P GG+ +AP + G P GG
Sbjct: 204 QGPPPAGGNPQQPQAP---PAGKPQGPPPPPQGG 234
Score = 32.0 bits (71), Expect = 1.5
Identities = 36/163 (22%), Positives = 57/163 (34%), Gaps = 26/163 (15%)
Query: 391 GDAPSRLSGDRTHGDAPSPLGGDRTHG--------DALSRLSGDRTHGDAPSHLSGDRTH 442
G+ P R P P GG+++ G + G+++ G P +R
Sbjct: 44 GNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPER-- 101
Query: 443 GDAPSPLGGDRTHGDAPSPLSGDRTHGDALSRLSGDRTHGDPLSRLSRDRKHGDAPSPLS 502
P P GG+++ G P P +R G+++H P +R P P
Sbjct: 102 ---PPPQGGNQSQGTPPPPGKPERPPPQ-----GGNQSHRPPPPPGKPER-----PPPQG 148
Query: 503 GDCTHGDAPSPLSGDRTHGDPLSRLSGDRKHGDAPSPLSGDHQ 545
G+ + G P P + G P + R P G Q
Sbjct: 149 GNQSQGPPPHP---GKPEGPPPQEGNKSRSARSPPGKPQGPPQ 188
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 37.4 bits (85), Expect = 0.036
Identities = 67/311 (21%), Positives = 111/311 (35%), Gaps = 54/311 (17%)
Query: 254 LGGDRTHGEAPSRLSGDRTH-----GDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSG 308
L D + E+PS +SG G+ P R + GG+++ G P
Sbjct: 19 LNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRP--- 75
Query: 309 DRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGDRTHG--------DAPSRLGG 360
+ G P GG+++ G P + G P GG+++ G + P GG
Sbjct: 76 GKPEGPPPQ--GGNQSQGPPPRP---GKPEGQPPQ--GGNQSQGPPPRPGKPEGPPPQGG 128
Query: 361 DRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSRLSGDRTHGDAPSPLGGDRTHGDAL 420
+++ G P + G P G+++ G P + P P GG+++ G
Sbjct: 129 NQSQGPPPRP---GKPEGPPPQ--GGNQSQGPPPRP-----GKPEGPPPQGGNQSQGPPP 178
Query: 421 SRLSGDRTHGDAPSHLSGDRTHG--------DAPSPLGGDRTHGDAPSPLSGDRTHGDAL 472
+ G P G+++ G + P P GG+++ G P P +
Sbjct: 179 HP---GKPEGPPPQ--GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGG 233
Query: 473 SRLSGDRTH-GDPLSRLSRDRKHGDAPSPLSGDCTHGDAPSPLSGDRTHGDPLSRLSGDR 531
++ G H G P ++ P P P P G+ PL +G +
Sbjct: 234 NKPQGPPPHPGKPQGPPPQEGNKPQRPPPPG----RPQGPPPPGGNPQ--QPLPPPAG-K 286
Query: 532 KHGDAPSPLSG 542
G P P G
Sbjct: 287 PQGPPPPPQGG 297
>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
Length = 1894
Score = 37.0 bits (84), Expect = 0.048
Identities = 52/225 (23%), Positives = 74/225 (32%), Gaps = 27/225 (12%)
Query: 92 GDAPSRLIGDRKHGDAPSRLIGDR--KHGDAPSRLIGDRKHGDAPSPLIGDRTHGDAPSR 149
G +P G +P+R R +H P R+ R P P + H P
Sbjct: 962 GHSPKAQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQ- 1020
Query: 150 LSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHG 209
R G +PS T P P S R+H + + R G P+ L
Sbjct: 1021 ---SRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSR--GMLPTAL--QNQDE 1073
Query: 210 DAPSRLSGDR---KHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGD----RTHGE 262
DA D + D + R A S + + GGD R H
Sbjct: 1074 DAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHRSQRGHAA 1133
Query: 263 APSRLSGDRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLS 307
+P+R PSR GG ++ PSR ++ + LS
Sbjct: 1134 SPAR----------PSRPGGPQSRARVPSRAAPGKSEPPSKRPLS 1168
Score = 35.0 bits (79), Expect = 0.18
Identities = 50/231 (21%), Positives = 72/231 (31%), Gaps = 26/231 (11%)
Query: 156 HGDAPSPLSGDRTHGDAPSPLSGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRL 215
H P S DR A P + + H P R++ R P H P
Sbjct: 963 HSPKAQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQ-- 1020
Query: 216 SGDRKHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSGDRTHGD 275
R G +PS+ T P S R+H + R G P+ L D
Sbjct: 1021 --SRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSR--GMLPTALQNQDE--D 1074
Query: 276 APSRLGGDRTHGDAPS-RLGGDRTHGDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSRLSG 334
A D T +A R + ++P+ G H
Sbjct: 1075 AQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDH-------RS 1127
Query: 335 DRTHGDAPSRLGGDRTHGDAPSRLGGDRTHGDAPSRLSGDRTHGDAPSRLS 385
R H +P+R PSR GG ++ PSR + ++ + LS
Sbjct: 1128 QRGHAASPAR----------PSRPGGPQSRARVPSRAAPGKSEPPSKRPLS 1168
Score = 34.3 bits (77), Expect = 0.31
Identities = 51/212 (24%), Positives = 71/212 (33%), Gaps = 27/212 (12%)
Query: 127 DRKHGDAPSPLIGDRTHGDAPSRLSGDRTHGDAPSPLSGDRTHGDAPSPLSGDRTHGDAP 186
DR A P + H P R++ R P P H P P S D +
Sbjct: 973 DRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQH--HPGPQSRDAGRSPSQ 1030
Query: 187 SRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRKHGDAPSRLGGDRTHGDAPSRLSGDRT 246
RLS + P+ G R+H + + R G P+ L DA D T
Sbjct: 1031 PRLSLTQAGRPRPTSQG--RSHSSSDPYTASSR--GMLPTAL--QNQDEDAQGSYDDDST 1084
Query: 247 H---GDAPSRLGGDRTHGEAPSRLSGDRTHGDAPSRLGGD----RTHGDAPSRLGGDRTH 299
D + R A S + + GGD R H +P+R
Sbjct: 1085 EVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHRSQRGHAASPAR------- 1137
Query: 300 GDAPSRLSGDRTHGDAPSRLGGDRTHGEAPSR 331
PSR G ++ PSR ++ E PS+
Sbjct: 1138 ---PSRPGGPQSRARVPSRAAPGKS--EPPSK 1164
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.136 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,313,296
Number of Sequences: 37866
Number of extensions: 1897468
Number of successful extensions: 5315
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 109
Number of HSP's that attempted gapping in prelim test: 3383
Number of HSP's gapped (non-prelim): 686
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.