Guide to the Human Genome
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Search of human proteins with 239744754

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239744754 PREDICTED: hypothetical protein XP_002343260 [Homo
sapiens]
         (519 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239744754 PREDICTED: hypothetical protein XP_002343260 [Homo ...  1072   0.0  
gi|239755949 PREDICTED: hypothetical protein [Homo sapiens]          1069   0.0  
gi|239750452 PREDICTED: hypothetical protein [Homo sapiens]          1069   0.0  
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ...    48   2e-05
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]     41   0.003
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]     41   0.003
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                40   0.004
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        40   0.005
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]     39   0.011
gi|119226260 calcium homeostasis endoplasmic reticulum protein [...    39   0.015
gi|239757778 PREDICTED: hypothetical protein [Homo sapiens]            37   0.044
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    37   0.044
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]     37   0.057
gi|221139764 PHD and ring finger domains 1 [Homo sapiens]              37   0.057
gi|50962882 G patch domain containing 8 [Homo sapiens]                 36   0.074
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]    36   0.097
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    36   0.097
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     35   0.13 
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    35   0.13 
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    35   0.13 
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           35   0.13 
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           35   0.13 
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    35   0.13 
gi|239755335 PREDICTED: hypothetical protein [Homo sapiens]            34   0.28 
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]          34   0.28 
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    34   0.28 
gi|150170729 microtubule associated serine/threonine kinase 3 [H...    34   0.28 
gi|50083281 KIAA1853 protein [Homo sapiens]                            34   0.28 
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          34   0.37 
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa...    34   0.37 

>gi|239744754 PREDICTED: hypothetical protein XP_002343260 [Homo
           sapiens]
          Length = 519

 Score = 1072 bits (2772), Expect = 0.0
 Identities = 519/519 (100%), Positives = 519/519 (100%)

Query: 1   MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG 60
           MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG
Sbjct: 1   MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG 60

Query: 61  LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG 120
           LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG
Sbjct: 61  LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG 120

Query: 121 QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN 180
           QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN
Sbjct: 121 QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN 180

Query: 181 HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW 240
           HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW
Sbjct: 181 HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW 240

Query: 241 VSLQHQESQVPEGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA 300
           VSLQHQESQVPEGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA
Sbjct: 241 VSLQHQESQVPEGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA 300

Query: 301 PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV 360
           PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV
Sbjct: 301 PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV 360

Query: 361 FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR 420
           FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR
Sbjct: 361 FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR 420

Query: 421 TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG 480
           TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG
Sbjct: 421 TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG 480

Query: 481 PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP 519
           PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP
Sbjct: 481 PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP 519


>gi|239755949 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 524

 Score = 1069 bits (2764), Expect = 0.0
 Identities = 518/519 (99%), Positives = 518/519 (99%)

Query: 1   MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG 60
           MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG
Sbjct: 6   MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG 65

Query: 61  LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG 120
           LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG
Sbjct: 66  LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG 125

Query: 121 QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN 180
           QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN
Sbjct: 126 QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN 185

Query: 181 HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW 240
           HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW
Sbjct: 186 HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW 245

Query: 241 VSLQHQESQVPEGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA 300
           VSLQHQESQV EGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA
Sbjct: 246 VSLQHQESQVSEGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA 305

Query: 301 PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV 360
           PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV
Sbjct: 306 PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV 365

Query: 361 FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR 420
           FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR
Sbjct: 366 FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR 425

Query: 421 TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG 480
           TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG
Sbjct: 426 TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG 485

Query: 481 PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP 519
           PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP
Sbjct: 486 PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP 524


>gi|239750452 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 524

 Score = 1069 bits (2764), Expect = 0.0
 Identities = 518/519 (99%), Positives = 518/519 (99%)

Query: 1   MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG 60
           MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG
Sbjct: 6   MGTGTRTEVQPVDGRALPPPAHLLLHDGHGGPRQQEGLQWDQVPERVLHLVTAGDDLSPG 65

Query: 61  LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG 120
           LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG
Sbjct: 66  LVGSAEEDSPWGGRDEDGGAVTQGLWPGTRDRTVRGHPRRPRASKPTNSMRHFHPYPGDG 125

Query: 121 QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN 180
           QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN
Sbjct: 126 QSRGSIRSLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKN 185

Query: 181 HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW 240
           HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW
Sbjct: 186 HFYVGGGDRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQW 245

Query: 241 VSLQHQESQVPEGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA 300
           VSLQHQESQV EGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA
Sbjct: 246 VSLQHQESQVSEGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA 305

Query: 301 PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV 360
           PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV
Sbjct: 306 PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQFSQETV 365

Query: 361 FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR 420
           FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR
Sbjct: 366 FCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHR 425

Query: 421 TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG 480
           TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG
Sbjct: 426 TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMG 485

Query: 481 PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP 519
           PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP
Sbjct: 486 PSLHTGVGICCRNFQRYRILHISCRLRISSPEIPCGRWP 524


>gi|112821681 G protein-regulated inducer of neurite outgrowth 1
           [Homo sapiens]
          Length = 1008

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 82/361 (22%), Positives = 126/361 (34%), Gaps = 28/361 (7%)

Query: 131 LASSSAEALGICK---MVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSK-NHFYVGG 186
           L+   AE + + K   +  G E   SS   D  ++ SR  S+     +S  K N    G 
Sbjct: 435 LSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSGP 494

Query: 187 GD-RFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQWVSLQH 245
           GD R L      +A++AEP       G  GD +   + G    G+AA             
Sbjct: 495 GDPRSLGTAGPPSAVKAEPAT-----GGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVG 549

Query: 246 QESQVPEG-----PQAGDHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGA 300
           +E  V +G     P     ++ + +VV    +   V  G    +++G  E  P   +   
Sbjct: 550 KEDPVSKGKADAGPSGQGDSVSIGKVVSTPGKTVPVPSGKVDPVSLGKAEAIPEGKVGSL 609

Query: 301 PLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEG----VCDRQRVPDGQFS 356
           PL    P+  T      SG   P           G E     G    VC ++  P     
Sbjct: 610 PLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEK 669

Query: 357 QETVFCIRVVQQSPG-----GVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKA 411
            +   C +    + G      +  AD A        S    + LS +K  PSS S +   
Sbjct: 670 VDPGSCRKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPLSLEKTKPSSSSRQLDR 729

Query: 412 RLILHCRHRTGTRADTASASARARPRSRSRSRA---AESQARPQTRTRTRTRTTPPWPGP 468
           + +   R   G R        +A P S + + +    + +A    R+       PP PGP
Sbjct: 730 KALGSARSPEGARGSEGRVEPKAEPVSSTEASSLGQKDLEAAGAERSPCPEAAAPP-PGP 788

Query: 469 R 469
           R
Sbjct: 789 R 789


>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
          Length = 272

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 21/46 (45%), Positives = 36/46 (78%), Gaps = 1/46 (2%)

Query: 416 HCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRT 461
           H R R+ +R+ T S+S R+R RSRSRSR + S++R ++R+R+R+++
Sbjct: 183 HSRSRSRSRSRTRSSS-RSRSRSRSRSRKSYSRSRSRSRSRSRSKS 227



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)

Query: 387 LSGAHHILLSGDKLPPSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRA 444
           ++G    L+ G K    S S R ++R     R R+ +R+ +  + +R+R RSRSRSR+
Sbjct: 169 INGRKIKLIEGSKRHSRSRS-RSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRS 225



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 13/69 (18%)

Query: 424 RADTASASARARPRS------RSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTP 477
           R   + + +R+R RS      RSRSR+ +S +R ++R+R+R+R+       +  + +R+P
Sbjct: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRS-------KSRSVSRSP 234

Query: 478 VMGPSLHTG 486
           V   S   G
Sbjct: 235 VPEKSQKRG 243


>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
          Length = 272

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 21/46 (45%), Positives = 36/46 (78%), Gaps = 1/46 (2%)

Query: 416 HCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRT 461
           H R R+ +R+ T S+S R+R RSRSRSR + S++R ++R+R+R+++
Sbjct: 183 HSRSRSRSRSRTRSSS-RSRSRSRSRSRKSYSRSRSRSRSRSRSKS 227



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 1/58 (1%)

Query: 387 LSGAHHILLSGDKLPPSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRA 444
           ++G    L+ G K    S S R ++R     R R+ +R+ +  + +R+R RSRSRSR+
Sbjct: 169 INGRKIKLIEGSKRHSRSRS-RSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRS 225



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 13/69 (18%)

Query: 424 RADTASASARARPRS------RSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTP 477
           R   + + +R+R RS      RSRSR+ +S +R ++R+R+R+R+       +  + +R+P
Sbjct: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRS-------KSRSVSRSP 234

Query: 478 VMGPSLHTG 486
           V   S   G
Sbjct: 235 VPEKSQKRG 243


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 10/188 (5%)

Query: 128 SLNLASSSAEALGICKMVEGPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKNHFYVGGG 187
           +L  A++SA A G      GP++  SS  P ++ + S+ P+T S+  +    +H   G G
Sbjct: 120 TLAAAATSAPAPGA---PGGPQLAGSSAGPVTA-APSQPPTTCSSRFRVIKLDH---GSG 172

Query: 188 DRFLLVGCTLTAIEAEPPEEMLLIGRHGDVVQHAELGQAVDGEAAVVGHQGQWVSLQHQE 247
           + +     T         +  +L  R GD ++H+          + +G  G  V +    
Sbjct: 173 EPYRRGRWTCMEYYERDSDSSVLT-RSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVAS 231

Query: 248 SQVPEGPQAG-DHALQVCQVVEAQVQGDEVGPGSTATLTVGVTETPPPTSLHGAPLFLAK 306
            Q   GP++G D +L     +    +  +  P    + +VG  + PPP  + GA    + 
Sbjct: 232 MQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPP-VGGAVAQSSA 290

Query: 307 PLIPTPPA 314
           PL P P A
Sbjct: 291 PLPPFPGA 298


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 1/82 (1%)

Query: 396  SGDKLPPSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRT 455
            SG     S    R ++R  +  R R G+   + S + +   R+ SR R   S+  P +R 
Sbjct: 1791 SGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRK 1850

Query: 456  RTRTRTTP-PWPGPRCPATART 476
            R+R+RT+P PW   R  A+  T
Sbjct: 1851 RSRSRTSPAPWKRSRSRASPAT 1872



 Score = 35.8 bits (81), Expect = 0.097
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 397 GDKLPPSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTR 456
           G    P  P   +        R R+  R  + S S   R RSRSR+ A   ++R +T  R
Sbjct: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR 591

Query: 457 TRTRTTPPWPGPRCPATARTP 477
            R+R+  P    R  + +RTP
Sbjct: 592 RRSRSRTP---TRRRSRSRTP 609



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 5/58 (8%)

Query: 404 SPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRT 461
           +P+ R ++R     R R+ +R  T     R R RSR+ +R   S++R   R R+RTR+
Sbjct: 577 TPARRGRSRSRTPARRRSRSRTPT-----RRRSRSRTPARRGRSRSRTPARRRSRTRS 629



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 403  SSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTT 462
            SSP  + K R  L  R R+G+  +  S S  +  RSRS S + E + +P+   R ++ + 
Sbjct: 1561 SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGS-SPEVKDKPRAAPRAQSGSD 1619

Query: 463  PPWPGPRCPATARTP 477
               P P+ PA    P
Sbjct: 1620 SS-PEPKAPAPRALP 1633



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 11/77 (14%)

Query: 403  SSPSLRKKARLILHCRH---------RTGTRADTASASARARPRSRSRS-RAAESQARPQ 452
            SSP L +KARL    R          RT  R   + + +   P  +SRS R   S + P+
Sbjct: 1693 SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPR 1752

Query: 453  TRTRTRTRTTPPWPGPR 469
            T+T +R R   P P PR
Sbjct: 1753 TKTTSR-RGRSPSPKPR 1768



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 10/87 (11%)

Query: 402 PSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRT------ 455
           P+    R ++ +    R R+  R    S S     R RSRSR    + R ++RT      
Sbjct: 620 PARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSG 679

Query: 456 RTRTRTTPPWPGPRCPATARTPVMGPS 482
           R+R+RT    P  R  + +RTP  G S
Sbjct: 680 RSRSRT----PARRGRSRSRTPRRGRS 702



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 11/79 (13%)

Query: 403  SSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRS----RAAESQARPQTRTRTR 458
            +SP  R+++R     R     R   + AS  +R RSRSR+    R       P TR R+R
Sbjct: 1892 TSPVSRRRSR----SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947

Query: 459  TRTTPPWPGPRCPATARTP 477
            +RT P     R  + +RTP
Sbjct: 1948 SRTPPV---TRRRSRSRTP 1963



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 3/56 (5%)

Query: 408  RKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTP 463
            R +A  +   R R+ T   T   S    P +R RSR   S+  P TR R+R+RT P
Sbjct: 1912 RSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR---SRTPPVTRRRSRSRTPP 1964



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 17/88 (19%)

Query: 404  SPSLRKKARL----ILHCRHRTGT-----RADTASASARARPRSRSRS-----RAAESQA 449
            +P+ R+++R     +   R R+ T     R   +  S   R RSRSR+     R + S+ 
Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998

Query: 450  RPQTRTRTRTRTTPPWPGPRCPATARTP 477
             P TR R+R+RT+P     R  + +RTP
Sbjct: 1999 SPVTRRRSRSRTSPV---TRRRSRSRTP 2023



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 11/80 (13%)

Query: 405  PSLRKKARLILHCRHRTGTRADTASASARARPRSRSRS-----RAAESQARPQTRTRTRT 459
            P  R+++R       R  +R+ T+  + R   RSRSR+     R + S+  P TR R+R+
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRR---RSRSRTSPVTRRRSRSRTSPVTRRRSRS 2020

Query: 460  RTTPPWPGPRCPATARTPVM 479
            RT    P  R  + +RTP++
Sbjct: 2021 RTP---PAIRRRSRSRTPLL 2037



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 12/79 (15%)

Query: 408  RKKARLILHCRHRTGTRADTASAS-ARARPRSRSRSRA--------AESQARPQTRTRTR 458
            R +A    H R R+ T   +   S +R  P SR RSR+        + S+A P +R R+R
Sbjct: 1865 RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR 1924

Query: 459  TRTTPPWPGPRCPATARTP 477
            +RT P     R  + +RTP
Sbjct: 1925 SRTPPV---TRRRSRSRTP 1940



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 3/55 (5%)

Query: 418 RHRTGTRADTASASARARPRSRSRSRAAESQAR---PQTRTRTRTRTTPPWPGPR 469
           R R+ +R  T    +R+R     RSR+A+   R   PQ R R+R+   P W   R
Sbjct: 492 RGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSR 546



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 403  SSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTT 462
            SSP  + K+R     R R+   +   +  AR   RSRS S + E+++R   R R     +
Sbjct: 1674 SSPEPKTKSRT--PPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS 1731

Query: 463  PPWPGPRCPATAR 475
             P P  +  ++ R
Sbjct: 1732 SPEPAEKSRSSRR 1744



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 389 GAHHILLSGDKLPPSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQ 448
           G+H  + S       S    K+ +   H   R   R+ + + + R R RSR+ ++   S+
Sbjct: 448 GSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR 507

Query: 449 AR-PQTRTRTRTRTTPPWPGPRCP 471
           +R PQ R   R+R+   W   R P
Sbjct: 508 SRSPQWR---RSRSAQRWGRSRSP 528



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 10/83 (12%)

Query: 403  SSPSLRKKARLILHCRHRTGTRA----------DTASASARARPRSRSRSRAAESQARPQ 452
            SSP  +  A   L  R R+G+ +           +  +S    P+SR+  R + S   P+
Sbjct: 1620 SSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPK 1679

Query: 453  TRTRTRTRTTPPWPGPRCPATAR 475
            T++RT  R       P     AR
Sbjct: 1680 TKSRTPPRRRSSRSSPELTRKAR 1702



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 396  SGDKLPPSSPSLRKKARLILHCRHRTGT----RADTASASARARPRSRSRSRAAESQARP 451
            S  + PP S + R+ +R     + ++ T    R+  +S     + R   RSR+A S    
Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET 1716

Query: 452  QTRTRTRTRTTPPWPGPRCPATART 476
            ++RT  R R +P    P     +R+
Sbjct: 1717 RSRTPPRHRRSPSVSSPEPAEKSRS 1741


>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
          Length = 221

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 13/74 (17%)

Query: 404 SPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRS-------------RAAESQAR 450
           SP  R+++R     R R+ +R+  + + +R+R RSRSRS              ++ S++R
Sbjct: 121 SPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSR 180

Query: 451 PQTRTRTRTRTTPP 464
            ++R+R+R+R+ PP
Sbjct: 181 SRSRSRSRSRSPPP 194



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 18/42 (42%), Positives = 30/42 (71%)

Query: 418 RHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRT 459
           R R+  R   + + +R+R RSRSRSR + S++R +TR+R+R+
Sbjct: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRS 159



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 19/62 (30%), Positives = 39/62 (62%), Gaps = 3/62 (4%)

Query: 408 RKKARLILHCRHRTGTRADTASAS---ARARPRSRSRSRAAESQARPQTRTRTRTRTTPP 464
           R ++R     + R+  R+ + S+S   +R+R RSRSRSR+    ++ ++++R+R+++ P 
Sbjct: 152 RTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPK 211

Query: 465 WP 466
            P
Sbjct: 212 SP 213



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 16/39 (41%), Positives = 27/39 (69%)

Query: 423 TRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRT 461
           +R+      +R+R RSRSRSR+    +R ++R+RTR+R+
Sbjct: 119 SRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRS 157


>gi|119226260 calcium homeostasis endoplasmic reticulum protein
           [Homo sapiens]
          Length = 916

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 51/224 (22%), Positives = 87/224 (38%), Gaps = 37/224 (16%)

Query: 292 PPPTSLHGAPLFLAKP-----------LIPTPPALEISGGLYPPGTDLL--VYYPQGPEV 338
           PPP   +G P  + +            L+P  P  ++  GL  P   L    Y P  P+ 
Sbjct: 614 PPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPK- 672

Query: 339 GVEEGVCDRQRVPDGQFSQETVFCIRVVQQSPGGVAAADQA---QQGLHRLLSGAHHILL 395
                  D +  P    S+  +  +      P      +     Q GL+           
Sbjct: 673 -------DIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARR 725

Query: 396 -SGDKLPPSSPSL-RKKARLILHCRHRTGTRADTASAS---------ARARPRSRSRSRA 444
             G +   S PS  R +++       R+ +R+  +S S         +R+  RSRSRSR+
Sbjct: 726 RKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRS 785

Query: 445 AESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMGPSLHTGVG 488
               +R ++R+++R+R+    PG R  + +R+P   P    G+G
Sbjct: 786 RSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPT--PPSSAGLG 827


>gi|239757778 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 93

 Score = 37.0 bits (84), Expect = 0.044
 Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 418 RHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTP 477
           R  TGT   T +  A A P +R R+R       P++RTRT   TTPP     CP  A   
Sbjct: 30  RTSTGTGTSTRTIPAPA-PSARRRARPKPGAQLPRSRTRTPAWTTPP---TACPNGASVL 85

Query: 478 VMGPS 482
             GPS
Sbjct: 86  SGGPS 90


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 37.0 bits (84), Expect = 0.044
 Identities = 22/69 (31%), Positives = 41/69 (59%), Gaps = 4/69 (5%)

Query: 418 RHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGP---RCPATA 474
           RH + +R+ ++ + + +R RS +RSR+  S +  Q+R+R+R+R+  P P P   +    A
Sbjct: 487 RHHSSSRSRSSWSLSPSRSRSLTRSRS-HSPSPSQSRSRSRSRSQSPSPSPAREKLTRPA 545

Query: 475 RTPVMGPSL 483
            +P +G  L
Sbjct: 546 ASPAVGEKL 554


>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
          Length = 288

 Score = 36.6 bits (83), Expect = 0.057
 Identities = 17/46 (36%), Positives = 30/46 (65%)

Query: 416 HCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRT 461
           H   R+ ++ D+  + +++R RS SRSR+  S  R  TR+R+R+R+
Sbjct: 32  HTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRS 77


>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
          Length = 1648

 Score = 36.6 bits (83), Expect = 0.057
 Identities = 39/149 (26%), Positives = 61/149 (40%), Gaps = 29/149 (19%)

Query: 357  QETVFCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLIL- 415
            + TV C+ VV+  P    + D  Q   HR++     +         SS   RKKA+    
Sbjct: 956  ERTVTCVTVVE--PEAPPSPDVLQAATHRVVE----LRPPSRSRSTSSSRSRKKAKRKRV 1009

Query: 416  ---HCRHRTGTRADTASASARA--------RPR-----------SRSRSRAAESQARPQT 453
               H R R+GTR+++   S+R+        RPR           S  RS + E   R + 
Sbjct: 1010 SREHGRTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKA 1069

Query: 454  RTRTRTRTTPPWPGPRCPATARTPVMGPS 482
            + ++R     PW   R  + +R+   G S
Sbjct: 1070 KDKSREHRRGPWGHSRRTSRSRSGSPGSS 1098



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 416  HCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATAR 475
            H R R+  R D   + A  R R + RSR+  S+ R +   R R+R    WP  R  +  R
Sbjct: 1136 HQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSR--EKWPQTRSHSPER 1193


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 36.2 bits (82), Expect = 0.074
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 3/88 (3%)

Query: 376 ADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHRTGTRADTASAS-ARA 434
           +D +     +  S  H    S D    S    R ++R   H R R+ +R  + S+S +R+
Sbjct: 911 SDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRS--HTRERSRSRGRSRSSSCSRS 968

Query: 435 RPRSRSRSRAAESQARPQTRTRTRTRTT 462
           R + RSRS  A S  R ++ +R R+R+T
Sbjct: 969 RSKRRSRSTTAHSWQRSRSYSRDRSRST 996


>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
          Length = 771

 Score = 35.8 bits (81), Expect = 0.097
 Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 17/112 (15%)

Query: 374 AAADQAQQGLHRLLSGA---HHILLSGDKLPPSSPSLRKKARLILHCRHRTG-TRADTAS 429
           AAA   +   H  +S A    H+ ++G       P+ R +  L L   H    +  D A 
Sbjct: 599 AAAPATEGRAHPAVSRACSTPHVQVAGKA---ERPTARSEQYLTLSGAHDLSESELDVAG 655

Query: 430 ASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMGP 481
             +RA P+ +          RP    R   R  PP+PGP  PA A   + GP
Sbjct: 656 LQSRATPQCQ----------RPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGP 697


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 35.8 bits (81), Expect = 0.097
 Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 17/112 (15%)

Query: 374 AAADQAQQGLHRLLSGA---HHILLSGDKLPPSSPSLRKKARLILHCRHRTG-TRADTAS 429
           AAA   +   H  +S A    H+ ++G       P+ R +  L L   H    +  D A 
Sbjct: 802 AAAPATEGRAHPAVSRACSTPHVQVAGKA---ERPTARSEQYLTLSGAHDLSESELDVAG 858

Query: 430 ASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCPATARTPVMGP 481
             +RA P+ +          RP    R   R  PP+PGP  PA A   + GP
Sbjct: 859 LQSRATPQCQ----------RPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGP 900


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 29/100 (29%), Positives = 53/100 (53%), Gaps = 11/100 (11%)

Query: 363 IRVVQQSPGGVAAADQAQQGLH-RLLSGAHHILLSGDKLPPSSPSLRKKARLILHCRHRT 421
           IR+V+  PG       ++   H R  S + H   S  +   SS S   K+R     R R+
Sbjct: 170 IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSR-SGSSKSSHSKSR----SRSRS 224

Query: 422 GTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRT 461
           G+R+      +++R RS+SRSR+ + ++R  ++ ++R+R+
Sbjct: 225 GSRS-----RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRS 259



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 6/80 (7%)

Query: 402 PSSPSLRKKARLILHCRHRTGTRADTAS-----ASARARPRSRSRSRAAESQARPQTRTR 456
           P S   R  +R   H R R+ +R    S     +S  +  +SRSRSR+  S++R ++R+R
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG-SRSRSKSRSR 235

Query: 457 TRTRTTPPWPGPRCPATART 476
           +++R+       R P+  ++
Sbjct: 236 SQSRSRSKKEKSRSPSKEKS 255


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
            [Homo sapiens]
          Length = 1451

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 18/126 (14%)

Query: 64   SAEEDSPWGGRDEDGGAVTQGLWPGTRDRTV---RGHPR-RPRASKPTNSMRHFHPYPGD 119
            S    S     DED    TQ L PG R   V     HPR  P+AS    S         D
Sbjct: 992  STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD 1051

Query: 120  GQSR-----------GSIRSLNLASSSAEALGICKMVEG--PEMTDSSDSPDSSTSDSRD 166
            G+ +           G++ + +  S+S +A G  K+ +   PE+  ++ +P+SS  DS D
Sbjct: 1052 GKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESS-DDSED 1110

Query: 167  PSTSST 172
             S SS+
Sbjct: 1111 SSDSSS 1116


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
            sapiens]
          Length = 1450

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 38/126 (30%), Positives = 55/126 (43%), Gaps = 18/126 (14%)

Query: 64   SAEEDSPWGGRDEDGGAVTQGLWPGTRDRTV---RGHPR-RPRASKPTNSMRHFHPYPGD 119
            S    S     DED    TQ L PG R   V     HPR  P+AS    S         D
Sbjct: 992  STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD 1051

Query: 120  GQSR-----------GSIRSLNLASSSAEALGICKMVEG--PEMTDSSDSPDSSTSDSRD 166
            G+ +           G++ + +  S+S +A G  K+ +   PE+  ++ +P+SS  DS D
Sbjct: 1052 GKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESS-DDSED 1110

Query: 167  PSTSST 172
             S SS+
Sbjct: 1111 SSDSSS 1116


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 3/66 (4%)

Query: 397  GDKLPPSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTR 456
            G+K      SLR +++      H+  +R  T+ + +RAR RS S+S++  SQ R ++R+R
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHK--SRKRTSESRSRARKRS-SKSKSHRSQTRSRSRSR 1868

Query: 457  TRTRTT 462
             R R++
Sbjct: 1869 RRRRSS 1874



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 10/77 (12%)

Query: 419  HRTGTRADTASASARARPRSRSRSRAAES----------QARPQTRTRTRTRTTPPWPGP 468
            HR+ TR+ + S   R   RSRS+SR   S          + R ++R R R R++      
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916

Query: 469  RCPATARTPVMGPSLHT 485
               A +RTP      HT
Sbjct: 1917 TVRARSRTPSRRSRSHT 1933


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 3/66 (4%)

Query: 397  GDKLPPSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTR 456
            G+K      SLR +++      H+  +R  T+ + +RAR RS S+S++  SQ R ++R+R
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHK--SRKRTSESRSRARKRS-SKSKSHRSQTRSRSRSR 1868

Query: 457  TRTRTT 462
             R R++
Sbjct: 1869 RRRRSS 1874



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 10/77 (12%)

Query: 419  HRTGTRADTASASARARPRSRSRSRAAES----------QARPQTRTRTRTRTTPPWPGP 468
            HR+ TR+ + S   R   RSRS+SR   S          + R ++R R R R++      
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916

Query: 469  RCPATARTPVMGPSLHT 485
               A +RTP      HT
Sbjct: 1917 TVRARSRTPSRRSRSHT 1933


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 27/117 (23%)

Query: 291  TPPPTSLHGAPLFLAKPLIPTPPALEISGGLYPPGTDLLVYYPQGPEVGVEEGVCDR-QR 349
            TPPPT LH  P    +P  P PP         PP T  +V  P  P +   + + +R  +
Sbjct: 921  TPPPT-LHLVP----EPAAPPPP---------PPRTFQMVTTPF-PALPQPKALLERFHQ 965

Query: 350  VPDGQFSQETVFCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPS 406
            VP G           ++Q   GG  AA Q    L  L S A  +L+SG + P  +P+
Sbjct: 966  VPSGI----------ILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSG-QAPSGTPT 1011



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 60/250 (24%), Positives = 81/250 (32%), Gaps = 49/250 (19%)

Query: 242 SLQHQESQVPEGPQAGDHALQVCQVVEAQVQGDEVGPGSTATLTV--GVTETPPPTSLHG 299
           SL  Q    P GP A              +QG  + P + A L    G+ +   P +  G
Sbjct: 565 SLPTQSQPAPAGPAA-----------TTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATG 613

Query: 300 --APLFLAKPLIPTPPALE--ISGGLYPPGTDLLVYYPQGPEVGVEEGVCDRQRVPDGQF 355
             AP+   +P    PPA+   +  GL  P        P  P+          Q  P    
Sbjct: 614 EAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPT-PQAAAPPQATTPQPSPGLAS 672

Query: 356 SQETVFCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKLPPSSPSLRKKARLIL 415
           S E +    V+ Q P     A   Q  L   L        S   L    P L   A +I+
Sbjct: 673 SPEKI----VLGQPPSATPTAILTQDSLQMFLPQER----SQQPLSAEGPHLSVPASVIV 724

Query: 416 HCRHRTGTRADTASASARARPRSRSRS---RAAESQARPQTRTRTRTRTTPPWPGPRCPA 472
                  +    A   A A P ++      +A +SQA P              P P+ PA
Sbjct: 725 -------SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA-------------PAPQIPA 764

Query: 473 TARTPVMGPS 482
            A     GPS
Sbjct: 765 AAPLKGPGPS 774


>gi|239755335 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 515

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 12/170 (7%)

Query: 147 GPEMTDSSDSPDSSTSDSRDPSTSSTYIKSKSKNHFYVGGGDRFLLVGCTLTAIEAEPPE 206
           G + T  + +  SS+S +  P+TSST+ ++   +HF  G GD+ L  G  L ++ A+ PE
Sbjct: 172 GSQGTQEAPTNLSSSSQAPSPATSSTHPQTPVPSHFQ-GLGDQSLSPG-NLGSL-AKKPE 228

Query: 207 EMLLIGRHGDVVQ---HAELG-QAVDGEAAVVGHQGQWVSLQHQESQVPEGPQAGDHALQ 262
            +   G H  + +    AE G +  +    V G +       H    V  G     H   
Sbjct: 229 GLAERGAHSHLWRLKTVAERGCRRQEEPDGVAGSRADPTLGFHHLLCVRLGQSLQQHQQD 288

Query: 263 VCQVVE-AQVQGDEVGPGSTAT----LTVGVTETPPPTSLHGAPLFLAKP 307
            CQ  + A+  G ++GP   ++      +    +P P++L G P  L +P
Sbjct: 289 QCQGGKVAEPHGRDLGPHLASSGQPHPALPPEASPGPSALAGTPQLLVQP 338


>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
          Length = 334

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 15/38 (39%), Positives = 27/38 (71%)

Query: 423 TRADTASASARARPRSRSRSRAAESQARPQTRTRTRTR 460
           +R+ + +  +R+RPR RS SR++E  +  +TR+R+R R
Sbjct: 99  SRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDR 136



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 2/47 (4%)

Query: 418 RHRTGTRADTASASARARPRSRSRSRAAESQ-ARPQTRTRTRTRTTP 463
           RHR+ + +   S   R+R RSR R ++   Q +R ++RTR R+R+ P
Sbjct: 67  RHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTR-RSRSRP 112



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 6/66 (9%)

Query: 400 LPPSSPSLRKKARLILHCRHRTGTRADTASASARAR------PRSRSRSRAAESQARPQT 453
           L P S S  ++ R         G+R   + + +R R       RSRS+SR   S++RP+ 
Sbjct: 55  LQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRL 114

Query: 454 RTRTRT 459
           R+ +R+
Sbjct: 115 RSHSRS 120


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 18/51 (35%), Positives = 23/51 (45%)

Query: 421  TGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRTTPPWPGPRCP 471
            T T   T + + R     R+ +R   +  R  TRT T T  TP  P P CP
Sbjct: 1463 TTTPRPTTATTRRTTTTRRTTTRRPTTTVRTTTRTTTTTTPTPTTPIPTCP 1513


>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
            sapiens]
          Length = 1309

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 33/112 (29%), Positives = 42/112 (37%), Gaps = 19/112 (16%)

Query: 388  SGAHHILLSGDKLPPSSPSLRKKARLILHCRHRT-GTRADTASASARARPRSRSRSRAAE 446
            SG HH L S + LP  SP+          CR       ADT ++   A P S S +  A 
Sbjct: 1094 SGLHHSLSSSESLP-GSPTHSLSPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASPAA 1152

Query: 447  S----------------QARPQTRTRTRTRTTPPWPGPRCPATARTPVMGPS 482
            +                  RP+T  R  T + PP P   CP  +  P   PS
Sbjct: 1153 AGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSP-LACPPISAPPPRSPS 1203


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/50 (38%), Positives = 33/50 (66%), Gaps = 1/50 (2%)

Query: 428 ASASARARPRSRSRSRA-AESQARPQTRTRTRTRTTPPWPGPRCPATART 476
           +S+S+R+  RS SRSR+ + S+ R +TRT + + +  P PG R  + +R+
Sbjct: 538 SSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRS 587



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 1/62 (1%)

Query: 401 PPSSPSLRKKARLILHCRHRTGTRADTASAS-ARARPRSRSRSRAAESQARPQTRTRTRT 459
           P SS SL   +        R+ +R+ + S S +R+R RSR+R+ ++ S   P   +R+R+
Sbjct: 524 PSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRS 583

Query: 460 RT 461
           R+
Sbjct: 584 RS 585



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 19/48 (39%), Positives = 30/48 (62%), Gaps = 1/48 (2%)

Query: 408 RKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAESQARPQTRT 455
           R ++R     R RT + + + S S  +R RSRSRSR + S++R Q+R+
Sbjct: 553 RSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR-SRSRSRSQSRS 599



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 7/44 (15%)

Query: 418 RHRTGTRADTASASARARPRSRSRSRAAESQARPQTRTRTRTRT 461
           R R+ TR  ++S+S    P SRSRSR+       ++R+R+R+R+
Sbjct: 559 RRRSRTRTSSSSSSRSPSPGSRSRSRS-------RSRSRSRSRS 595


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 33.9 bits (76), Expect = 0.37
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 9/89 (10%)

Query: 396 SGDKLPPSSPSLRKKARLILHCRHRTGTRADTAS-------ASARARPRSRSRSRA-AES 447
           S +  P SS  ++   ++I+  R ++ +  + +S       AS R+RP+S S+SR+   S
Sbjct: 231 SDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRS 290

Query: 448 QARPQTRTRTRTRTTPPWPGPRCPATART 476
           ++  Q RT +R R +  W      A +RT
Sbjct: 291 RSGSQKRTHSRVR-SHSWKRNHSRARSRT 318


>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
           sapiens]
          Length = 441

 Score = 33.9 bits (76), Expect = 0.37
 Identities = 38/144 (26%), Positives = 54/144 (37%), Gaps = 13/144 (9%)

Query: 341 EEGVCDRQRVPDGQFSQETVFCIRVVQQSPGGVAAADQAQQGLHRLLSGAHHILLSGDKL 400
           E G+ D   + D      T    R+V +S  G  + D+  +G      G   I       
Sbjct: 105 EAGIGDTPSLEDEAAGHVTQ--ARMVSKSKDGTGSDDKKAKGA----DGKTKIATPRGAA 158

Query: 401 PPSSPSLRKKARLILHCRHRTGTRADTASASARARPRSRSRSRAAE--SQARPQTRTRTR 458
           PP         R+      +T     T  +S    P+S  RS  +   S   P +R+RT 
Sbjct: 159 PPGQKGQANATRIPA----KTPPAPKTPPSSGEP-PKSGDRSGYSSPGSPGTPGSRSRTP 213

Query: 459 TRTTPPWPGPRCPATARTPVMGPS 482
           +  TPP   P+  A  RTP   PS
Sbjct: 214 SLPTPPTREPKKVAVVRTPPKSPS 237


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,578,740
Number of Sequences: 37866
Number of extensions: 1439938
Number of successful extensions: 7825
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 151
Number of HSP's that attempted gapping in prelim test: 6739
Number of HSP's gapped (non-prelim): 973
length of query: 519
length of database: 18,247,518
effective HSP length: 107
effective length of query: 412
effective length of database: 14,195,856
effective search space: 5848692672
effective search space used: 5848692672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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