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Search of human proteins with 116805322
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116805322 gamma filamin isoform a [Homo sapiens]
(2725 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116805322 gamma filamin isoform a [Homo sapiens] 5564 0.0
gi|188595687 gamma filamin isoform b [Homo sapiens] 5472 0.0
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens] 3355 0.0
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens] 3331 0.0
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s... 3205 0.0
gi|239755812 PREDICTED: similar to spectrin, beta, non-erythrocy... 192 3e-48
gi|4557241 actinin, alpha 3 [Homo sapiens] 164 8e-40
gi|12025678 actinin, alpha 4 [Homo sapiens] 160 1e-38
gi|4501893 actinin, alpha 2 [Homo sapiens] 158 8e-38
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 154 1e-36
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] 154 1e-36
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] 154 1e-36
gi|67782321 spectrin beta isoform a [Homo sapiens] 147 1e-34
gi|67782319 spectrin beta isoform b [Homo sapiens] 147 1e-34
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 147 1e-34
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 147 2e-34
gi|33188445 microfilament and actin filament cross-linker protei... 145 7e-34
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 143 2e-33
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 142 3e-33
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 142 4e-33
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 141 8e-33
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 141 8e-33
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 141 8e-33
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 141 8e-33
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 141 8e-33
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 141 8e-33
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 139 3e-32
gi|221316624 dystonin isoform 4 [Homo sapiens] 139 5e-32
gi|221316622 dystonin isoform 3 [Homo sapiens] 139 5e-32
gi|221316618 dystonin isoform 2 [Homo sapiens] 139 5e-32
>gi|116805322 gamma filamin isoform a [Homo sapiens]
Length = 2725
Score = 5564 bits (14435), Expect = 0.0
Identities = 2725/2725 (100%), Positives = 2725/2725 (100%)
Query: 1 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL 60
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL
Sbjct: 1 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL 60
Query: 61 QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK 120
QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK
Sbjct: 61 QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK 120
Query: 121 AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN 180
AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
Sbjct: 121 AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN 180
Query: 181 FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI 240
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI
Sbjct: 181 FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI 240
Query: 241 VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV 300
VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV
Sbjct: 241 VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV 300
Query: 301 QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE 360
QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
Sbjct: 301 QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE 360
Query: 361 RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR 420
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR
Sbjct: 361 RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR 420
Query: 421 RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS 480
RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS
Sbjct: 421 RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS 480
Query: 481 GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV 540
GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
Sbjct: 481 GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV 540
Query: 541 VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE 600
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE
Sbjct: 541 VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE 600
Query: 601 VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP 660
VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP
Sbjct: 601 VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP 660
Query: 661 APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP 720
APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
Sbjct: 661 APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP 720
Query: 721 NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 780
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK
Sbjct: 721 NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 780
Query: 781 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR 840
ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR
Sbjct: 781 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR 840
Query: 841 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA 900
YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
Sbjct: 841 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA 900
Query: 901 KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV
Sbjct: 901 KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
Query: 961 APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG
Sbjct: 961 APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
Query: 1021 AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP 1080
AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
Sbjct: 1021 AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP 1080
Query: 1081 APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI 1140
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI
Sbjct: 1081 APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI 1140
Query: 1141 PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA 1200
PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA
Sbjct: 1141 PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA 1200
Query: 1201 EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV 1260
EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
Sbjct: 1201 EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV 1260
Query: 1261 EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE 1320
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE
Sbjct: 1261 EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE 1320
Query: 1321 EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT 1380
EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT
Sbjct: 1321 EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT 1380
Query: 1381 GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV 1440
GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
Sbjct: 1381 GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV 1440
Query: 1441 VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT 1500
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT
Sbjct: 1441 VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT 1500
Query: 1501 HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV 1560
HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV
Sbjct: 1501 HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV 1560
Query: 1561 EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE 1620
EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
Sbjct: 1561 EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE 1620
Query: 1621 IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC 1680
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC
Sbjct: 1621 IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC 1680
Query: 1681 TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPH 1740
TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPH
Sbjct: 1681 TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPH 1740
Query: 1741 EEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG 1800
EEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
Sbjct: 1741 EEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG 1800
Query: 1801 EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR 1860
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR
Sbjct: 1801 EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR 1860
Query: 1861 HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP 1920
HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP
Sbjct: 1861 HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP 1920
Query: 1921 TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS 1980
TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS
Sbjct: 1921 TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS 1980
Query: 1981 IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD 2040
IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD
Sbjct: 1981 IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD 2040
Query: 2041 ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY 2100
ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY
Sbjct: 2041 ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY 2100
Query: 2101 CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI 2160
CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI
Sbjct: 2101 CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI 2160
Query: 2161 PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA 2220
PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA
Sbjct: 2161 PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA 2220
Query: 2221 VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP 2280
VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP
Sbjct: 2221 VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP 2280
Query: 2281 QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR 2340
QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR
Sbjct: 2281 QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR 2340
Query: 2341 EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP 2400
EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP
Sbjct: 2341 EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP 2400
Query: 2401 VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD 2460
VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD
Sbjct: 2401 VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD 2460
Query: 2461 SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT 2520
SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT
Sbjct: 2461 SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT 2520
Query: 2521 GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP 2580
GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP
Sbjct: 2521 GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP 2580
Query: 2581 QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT 2640
QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT
Sbjct: 2581 QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT 2640
Query: 2641 RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE 2700
RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE
Sbjct: 2641 RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE 2700
Query: 2701 KGDYILIVKWGDESVPGSPFKVKVP 2725
KGDYILIVKWGDESVPGSPFKVKVP
Sbjct: 2701 KGDYILIVKWGDESVPGSPFKVKVP 2725
>gi|188595687 gamma filamin isoform b [Homo sapiens]
Length = 2692
Score = 5472 bits (14195), Expect = 0.0
Identities = 2692/2725 (98%), Positives = 2692/2725 (98%), Gaps = 33/2725 (1%)
Query: 1 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL 60
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL
Sbjct: 1 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL 60
Query: 61 QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK 120
QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK
Sbjct: 61 QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK 120
Query: 121 AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN 180
AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
Sbjct: 121 AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN 180
Query: 181 FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI 240
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI
Sbjct: 181 FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI 240
Query: 241 VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV 300
VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV
Sbjct: 241 VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV 300
Query: 301 QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE 360
QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
Sbjct: 301 QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE 360
Query: 361 RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR 420
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR
Sbjct: 361 RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR 420
Query: 421 RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS 480
RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS
Sbjct: 421 RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS 480
Query: 481 GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV 540
GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
Sbjct: 481 GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV 540
Query: 541 VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE 600
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE
Sbjct: 541 VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE 600
Query: 601 VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP 660
VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP
Sbjct: 601 VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP 660
Query: 661 APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP 720
APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
Sbjct: 661 APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP 720
Query: 721 NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 780
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK
Sbjct: 721 NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK 780
Query: 781 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR 840
ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR
Sbjct: 781 ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR 840
Query: 841 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA 900
YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
Sbjct: 841 YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA 900
Query: 901 KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV
Sbjct: 901 KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
Query: 961 APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG
Sbjct: 961 APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
Query: 1021 AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP 1080
AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
Sbjct: 1021 AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP 1080
Query: 1081 APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI 1140
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI
Sbjct: 1081 APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI 1140
Query: 1141 PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA 1200
PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA
Sbjct: 1141 PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA 1200
Query: 1201 EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV 1260
EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
Sbjct: 1201 EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV 1260
Query: 1261 EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE 1320
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE
Sbjct: 1261 EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE 1320
Query: 1321 EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT 1380
EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT
Sbjct: 1321 EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT 1380
Query: 1381 GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV 1440
GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
Sbjct: 1381 GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV 1440
Query: 1441 VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT 1500
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT
Sbjct: 1441 VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT 1500
Query: 1501 HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV 1560
HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV
Sbjct: 1501 HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV 1560
Query: 1561 EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE 1620
EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
Sbjct: 1561 EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE 1620
Query: 1621 IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC 1680
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC
Sbjct: 1621 IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC 1680
Query: 1681 TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPH 1740
TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL
Sbjct: 1681 TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVL------- 1733
Query: 1741 EEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG 1800
ATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
Sbjct: 1734 --------------------------ATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG 1767
Query: 1801 EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR 1860
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR
Sbjct: 1768 EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR 1827
Query: 1861 HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP 1920
HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP
Sbjct: 1828 HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP 1887
Query: 1921 TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS 1980
TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS
Sbjct: 1888 TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS 1947
Query: 1981 IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD 2040
IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD
Sbjct: 1948 IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD 2007
Query: 2041 ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY 2100
ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY
Sbjct: 2008 ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY 2067
Query: 2101 CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI 2160
CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI
Sbjct: 2068 CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI 2127
Query: 2161 PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA 2220
PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA
Sbjct: 2128 PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA 2187
Query: 2221 VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP 2280
VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP
Sbjct: 2188 VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP 2247
Query: 2281 QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR 2340
QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR
Sbjct: 2248 QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR 2307
Query: 2341 EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP 2400
EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP
Sbjct: 2308 EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP 2367
Query: 2401 VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD 2460
VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD
Sbjct: 2368 VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD 2427
Query: 2461 SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT 2520
SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT
Sbjct: 2428 SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT 2487
Query: 2521 GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP 2580
GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP
Sbjct: 2488 GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP 2547
Query: 2581 QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT 2640
QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT
Sbjct: 2548 QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT 2607
Query: 2641 RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE 2700
RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE
Sbjct: 2608 RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE 2667
Query: 2701 KGDYILIVKWGDESVPGSPFKVKVP 2725
KGDYILIVKWGDESVPGSPFKVKVP
Sbjct: 2668 KGDYILIVKWGDESVPGSPFKVKVP 2692
>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
Length = 2647
Score = 3355 bits (8698), Expect = 0.0
Identities = 1692/2660 (63%), Positives = 2011/2660 (75%), Gaps = 89/2660 (3%)
Query: 3 NNSGYSDAGLGLGDETD----EMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLT 58
+ +G S AG G D EMP+TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV KR+
Sbjct: 6 SRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIA 65
Query: 59 DLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSID 118
+LQ DLSDGLRLIALLEVLSQK+M+RK + RP FRQM+LENVSVALEFL+RE IKLVSID
Sbjct: 66 NLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSID 125
Query: 119 SKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPI 178
SKAIVDGNLKLILGLIWTLILHYSISMPMW++E+DE+A+KQTPKQRLLGWIQNK+PQLPI
Sbjct: 126 SKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPI 185
Query: 179 TNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPE 238
TNF+RDWQ G+ALGALVD+CAPGLCPDW++WD ++PV NAREAMQQADDWLG+PQVI PE
Sbjct: 186 TNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPE 245
Query: 239 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHF 298
EIVDPNVDEHSVMTYLSQFPKAKLKPGAP+R K LNPKKA AYGPGIEP GN V + A F
Sbjct: 246 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPK-LNPKKARAYGPGIEPTGNMVKKRAEF 304
Query: 299 TVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQN 358
TV+T AG GEVLVY+EDP GH EEAKV NNDK+RT++V YVP+V G HKVTVLFAGQ+
Sbjct: 305 TVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQH 364
Query: 359 IERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQ 418
I +SPFEV V + GDA+KV+A+GPGLEP GN+ANK TYF+I+TAGAGTG+V VVI DP
Sbjct: 365 IAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPM 424
Query: 419 GRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACR 478
G++ TVE LE +GDST+RC+Y+P MEG HTVHV FAG PI RSP+ V V +ACNP+ACR
Sbjct: 425 GQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACR 484
Query: 479 ASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYY 538
A GRGLQPKGVRVKE ADFKV+TKGAGSGELKVTVKGPKG EE VK ++ GDGV+ EYY
Sbjct: 485 AVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYY 543
Query: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIG 598
P+VPG Y+VTITWGG I RSPFEV+V E G QKVRAWGPGLE G VGKSADFVVEAIG
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 599 TEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHI 658
+VGTLGFS+EGPSQAKIECDDKGDGSCDVRYWP E GEYAVHV+C+ EDIR SPF+A I
Sbjct: 604 DDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADI 663
Query: 659 LPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKV 718
AP D PD+VKA GPGLE TG V+KPAEFT+DA+ GK L++ QD +GCP++ V
Sbjct: 664 RDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALV 723
Query: 719 IPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTG 778
NG+GT+ CSYVP KP+KHT ++SWGGV++P SPFRVNVG GSHP +VKVYGPGV KTG
Sbjct: 724 KDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTG 783
Query: 779 LKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGA 838
LKA+EPTYFTVDC+EAGQGDVSIGIKCAPGVVGPAEADIDFDII+NDNDTFTVKYTP GA
Sbjct: 784 LKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGA 843
Query: 839 GRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAG 898
G YTIMVLFA+Q P SP +KV+PSHDASKVKAEGPGL+RTGVE+GKPTHFTV K AG
Sbjct: 844 GSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG 903
Query: 899 KAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVV 958
K KLDVQF+G KG+ VRD +IID+HD +YTVKYT VQQG + V VTYGGDP+PKSPF V
Sbjct: 904 KGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSV 963
Query: 959 NVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPG 1018
V+P LDLSKIKV GL KV VG++Q F+V ++GAGGQG++ ++ PS +PCK+EPG
Sbjct: 964 AVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPG 1023
Query: 1019 GGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVG 1078
GA+ VR++P EEGPY+V++TYDG PVPGSPF +E V P PSKV A+GPGL+GG G
Sbjct: 1024 LGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAG 1083
Query: 1079 TPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEA 1138
+PA F+IDTKGAGTGGLGLTVEGPCEA++EC DNGDG+C+VSY+PTEPG+Y INILFA+
Sbjct: 1084 SPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADT 1143
Query: 1139 HIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGV 1198
HIPGSPFKA + P FD SKV+ SGPGLER GE F VDCS AG AELTIEI S+AG+
Sbjct: 1144 HIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGL 1203
Query: 1199 KAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGP 1258
AEV I ++ DGT+ ITY P PG YT+TIKYGG PVP FP+++ V+PAVDTSGV+ GP
Sbjct: 1204 PAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGP 1263
Query: 1259 GVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTA 1318
G+E GV RE TTEF+VDAR+LT TGG HV ARV NPSG T+TYV D GDG Y+V+YT
Sbjct: 1264 GIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTP 1323
Query: 1319 YEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGA 1378
YEEG+H V+V YD VP SPF+V VTEGCDP+RVR GPG++ G NK N+FTVETRGA
Sbjct: 1324 YEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGA 1383
Query: 1379 GTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVK 1438
GTGGLGLA+EGPSEAKMSC DNKDGSC+VEYIP+ G Y +N+T+GG +PGSPF+VPV
Sbjct: 1384 GTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVH 1443
Query: 1439 DVVDPGKVKCSGPGLGAG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNG 1497
DV D KVKCSGPGL G VRA +PQ+F VD S+AG APLQV V GP G+ EPV+V DN
Sbjct: 1444 DVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNA 1503
Query: 1498 DGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPAS 1557
DGT TV+Y P+ +GPY+++V Y D+EVPRSPFK+KVLP HDASKV+ASGPGLN +G+PAS
Sbjct: 1504 DGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPAS 1563
Query: 1558 LPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYG 1617
LPVEFTIDA+DAGEGLL VQI DPEGKPKK +I+DN DGTYTV+Y+PD++GRYTI IKYG
Sbjct: 1564 LPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYG 1623
Query: 1618 GDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGK 1677
GDEIP+SP+R+ A+PTGDASKC VTVSIGGHGLGA +GP IQIG+ETVITVD KAAG+GK
Sbjct: 1624 GDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGK 1683
Query: 1678 VTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDP 1737
VTCTV TPDG+E+DVDVVEN DGTFDI+YTAP+PGKYVI +RFGGEH+PNSPF V A
Sbjct: 1684 VTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTAL-- 1741
Query: 1738 LPHEEEPSEVPQLRQPYAPPR----PGARPTHWATEEPVVPVEPME-SMLRPFNLVIPFA 1792
++PS P LR P+ G + T WA E P+V V ++ + LRPF+LVIPF
Sbjct: 1742 --AGDQPSVQPPLRSQQLAPQYTYAQGGQQT-WAPERPLVGVNGLDVTSLRPFDLVIPFT 1798
Query: 1793 VQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQF 1852
++KGE+TGEVRMPSGK A+P ITDNKDGT+TVRYAP+E GLH+M I+YD HIPGSPLQF
Sbjct: 1799 IKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQF 1858
Query: 1853 YVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDG 1912
YVD +N HV+AYGPGL+HG+VNKPATFT+ TKDAGEGGLSLA+EGPSKAEI+C DN+DG
Sbjct: 1859 YVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDG 1918
Query: 1913 TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITES 1972
TC+VSYLP PGDYSI+V+++++H+PGSPFTA++TGDDSMR S L VG++ D+ + I+E+
Sbjct: 1919 TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISET 1978
Query: 1973 DLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKIL 2032
DLS LTA++ PSG EEPCLLKRL N H+GISF PKE GEH+V V+K+G+HV +SP ++
Sbjct: 1979 DLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVV 2038
Query: 2033 VGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDME 2092
+ SEIGDAS+VRV G+GL EGHTF+ AEFI+DTR+AGYGGL LSIEGPSKVDIN ED+E
Sbjct: 2039 ISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLE 2098
Query: 2093 DGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGS 2152
DGTC+VTYCPTEPG YIINIKFAD+HVPGSPF+VKVTGEGR+KESITRRR+APS+A +GS
Sbjct: 2099 DGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGS 2158
Query: 2153 TCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGET-KREVRVEEST 2211
CDL+LKIP Q ++AQ T + T + E V V+
Sbjct: 2159 HCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKG 2218
Query: 2212 Q-VGGDPFPAVFGDF----LGRERLGSFGSITRQQEG----------EASSQDMTAQVTS 2256
Q V G PF G + R G G + R + G EA + + V
Sbjct: 2219 QHVPGSPFQFTVGPLGEGGAHKVRAGGPG-LERAEAGVPAEFSIWTREAGAGGLAIAVEG 2277
Query: 2257 PSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHK 2316
PS K E + + +D + V +V QE G + V+VK+ +H+P SPF V G A +
Sbjct: 2278 PS-KAEIS-FEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVAS-PSGDARR 2334
Query: 2317 VRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKA--EIAFEDRKDGSCGVSYV 2374
+ PA F++ + G + V PS A E + V ++
Sbjct: 2335 LTVSSLQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFI 2393
Query: 2375 VQEPGDYEVSIKFNDEHIPDSPFVVPVA--SLSDDARRLTVTSLQETGLKVNQPASFAVQ 2432
+E G Y + +KFN HIP SPF + V D ++ G PA F V
Sbjct: 2394 PRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVN 2453
Query: 2433 L-NGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGA-HIPGS 2490
N G + + PS +C + + + + + P G + I +K+ G HI GS
Sbjct: 2454 TSNAGAGALSVTIDGPSKVKMDC---QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGS 2510
Query: 2491 PFKIRV-----------GEQS--------------QAGDPG-------LVSAYGPGLEGG 2518
PFK +V E S Q G PG V A G GL
Sbjct: 2511 PFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKA 2570
Query: 2519 TTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHV------VTYTPMAPGNYL 2572
G S F V+ AG+ L V + GP + C E HV V+Y G Y
Sbjct: 2571 YVGQKSSFTVDCSKAGNNMLLVGVHGP---RTPCEEILVKHVGSRLYSVSYLLKDKGEYT 2627
Query: 2573 IAIKYGGPQHIVGSPFKAKV 2592
+ +K+ G +HI GSP++ V
Sbjct: 2628 LVVKW-GDEHIPGSPYRVVV 2646
Score = 1591 bits (4119), Expect = 0.0
Identities = 967/2450 (39%), Positives = 1352/2450 (55%), Gaps = 186/2450 (7%)
Query: 377 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTF 436
K A GPG+EP GN+ K F + T AG G+V V + DP G ++ +V + + TF
Sbjct: 283 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTF 342
Query: 437 RCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEAC-NPNACRASGRGLQPKGVRVKEVA 495
Y P + G H V V FAG I +SPF V+V ++ + + A G GL+P G +
Sbjct: 343 SVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTT 402
Query: 496 DFKVFTKGAGSGELKVTVKGP---KGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWG 552
F++FT GAG+GE++V ++ P KGT EP ++ GD + C Y P + G + V +T+
Sbjct: 403 YFEIFTAGAGTGEVEVVIQDPMGQKGTVEP-QLEARGDSTYRCSYQPTMEGVHTVHVTFA 461
Query: 553 GYAIPRSPFEVQVSPEAGVQKVRAWGPGLETG--QVGKSADFVVEAIGTEVGTLGFSIEG 610
G IPRSP+ V V RA G GL+ +V ++ADF V G G L +++G
Sbjct: 462 GVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKG 521
Query: 611 PS-QAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDK 669
P + +++ D GDG Y+P PG Y V + ++I SPF + +C K
Sbjct: 522 PKGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKV---GTECGNQK 578
Query: 670 VKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCS 729
V+A+GPGLE G +V K A+F ++A G L + I+ GDG+
Sbjct: 579 VRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECD--DKGDGSCDVR 634
Query: 730 YVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGS---HPERVKVYGPGVEKTGLKANEPTY 786
Y P + ++ + + ++ SPF ++ + HP+RVK GPG+EKTG+ N+P
Sbjct: 635 YWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAE 694
Query: 787 FTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVL 846
FTVD G+ + + ++ G P EA + N N T++ Y P ++T MV
Sbjct: 695 FTVDAKHGGKAPLRVQVQDNEGC--PVEALVK----DNGNGTYSCSYVPRKPVKHTAMVS 748
Query: 847 FANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQF 906
+ IP SPF + V +KVK GPG+ +TG++ +PT+FTV AG+ + +
Sbjct: 749 WGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGI 808
Query: 907 ------AGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
G A+ ++ DF+II N + ++TVKYT G+ + V + P SP V V
Sbjct: 809 KCAPGVVGPAEADI--DFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKV 866
Query: 961 APPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEP 1017
P D SK+K +G + V +G+ F+VN + AG +G+LDV+ + ++ ++
Sbjct: 867 EPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG-KGKLDVQFSGLTKGDAVRDVDI 925
Query: 1018 GGGAE-AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL 1076
+ V+Y P ++GP V++TY G P+P SPF+V D SK+ G G K
Sbjct: 926 IDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVD- 984
Query: 1077 VGTPAPFSIDTKGAG-TGGLGLTVEGPCEAKIECQDN---GDGSCAVSYLPTEPGEYTIN 1132
VG F++ +KGAG G + + GP A + C+ G + V +LP E G Y +
Sbjct: 985 VGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVE 1044
Query: 1133 ILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEI 1192
+ + +PGSPF PSKV+A GPGL+ G G A FT+D AG L + +
Sbjct: 1045 VTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTV 1104
Query: 1193 LSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSG 1252
+ E L +N DGT ++Y P PG Y I I + +P P + HV P D S
Sbjct: 1105 EGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASK 1162
Query: 1253 VKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTY 1312
VK SGPG+E EV +F VD S G +T + + +G + Y+ D+GDGT+
Sbjct: 1163 VKCSGPGLE-RATAGEVG-QFQVDCSS---AGSAELTIEICSEAGLPAEVYIQDHGDGTH 1217
Query: 1313 RVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEG-GLVNKAN-R 1370
+ Y G + V + Y VP P ++ V D + V+ +GPG+EG G+ +A
Sbjct: 1218 TITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTE 1277
Query: 1371 FTVETRG-AGTGG--LGLAIEGPSE--AKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGG 1425
F+V+ R TGG + + PS + +D DG VEY P+ G + V++T+ G
Sbjct: 1278 FSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDG 1337
Query: 1426 RPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPT 1485
P+P SPF+VPV + DP +V+ GPG+ +G + P FTV+ AG L +AV GP+
Sbjct: 1338 SPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNK-PNKFTVETRGAGTGGLGLAVEGPS 1396
Query: 1486 GVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRAS 1545
+ DN DG+ +V Y P G Y++ V Y +VP SPFK+ V DASKV+ S
Sbjct: 1397 EAK--MSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCS 1454
Query: 1546 GPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPD 1605
GPGL+ + A+LP F +D AG L V++ P+G + ++ DN DGT TV+Y+P
Sbjct: 1455 GPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPS 1514
Query: 1606 MSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETV 1665
G Y+I++ YG +E+P SPF++ LPT DASK V G GL P
Sbjct: 1515 REGPYSISVLYGDEEVPRSPFKVKVLPTHDASK----VKASGPGLNTTGVPA---SLPVE 1567
Query: 1666 ITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHI 1725
T+DAK AGEG + ++ P+G + +NHDGT+ + Y G+Y I I++GG+ I
Sbjct: 1568 FTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEI 1627
Query: 1726 PNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPF 1785
P SP+ V A +P + + G PT EE V+ V+
Sbjct: 1628 PFSPYRVRA---VPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTK------- 1677
Query: 1786 NLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHI 1845
A KG++T V P G ++ +N+DGT + Y + G + + +++ G H+
Sbjct: 1678 ------AAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHV 1731
Query: 1846 PGSPLQFYVDAINSRHVSAYGP---------------------------GLSHGMVNKPA 1878
P SP Q V A+ S P G++ V
Sbjct: 1732 PNSPFQ--VTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLR 1789
Query: 1879 TFTIV---TKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDK 1935
F +V T GE + + A+ T DNKDGT TV Y P+ G + + +R+D+
Sbjct: 1790 PFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNM 1849
Query: 1936 HIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLK-----ITESDLSQ--LTASIRAPSGNE 1988
HIPGSP + + + G + V K + D + L+ +I PS E
Sbjct: 1850 HIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAE 1909
Query: 1989 EPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWG 2048
C + + +S+ P G++ + V+ + +HV SPF V + S ++V
Sbjct: 1910 ISCTDNQ--DGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGS 1967
Query: 2049 KGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINC--EDMEDGTCKVTYCPTEPG 2106
A+ ++ L ++ PS + C + + +G +++ P E G
Sbjct: 1968 ----------AADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETG 2017
Query: 2107 TYIINIKFADKHVPGSPFTV-------------KVTGEGRMKESITRRRQAPSIATIGST 2153
+++++K +HV SP V +V+G+G + +
Sbjct: 2018 EHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGY 2077
Query: 2154 CDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQV 2213
L+L I G ++ + T R T G ++ + V
Sbjct: 2078 GGLSLSIEGP-----------SKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQ-HV 2125
Query: 2214 GGDPFPA-VFGDFLGRERLGSFGSITRQQEG-----------------EASSQDMTAQVT 2255
G PF V G+ +E SITR++ E S QDMTAQVT
Sbjct: 2126 PGSPFSVKVTGEGRVKE------SITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVT 2179
Query: 2256 SPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAH 2315
SPSGK AEIVEGE+ Y +RFVP EMG HTV+VKY+GQHVPGSPFQFTVGPLGEGGAH
Sbjct: 2180 SPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAH 2239
Query: 2316 KVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVV 2375
KVRAGG GLER AGVPAEFSIWTREAGAGGL+IAVEGPSKAEI+FEDRKDGSCGV+YVV
Sbjct: 2240 KVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVV 2299
Query: 2376 QEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNG 2435
QEPGDYEVS+KFN+EHIPDSPFVVPVAS S DARRLTV+SLQE+GLKVNQPASFAV LNG
Sbjct: 2300 QEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNG 2359
Query: 2436 ARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIR 2495
A+G IDA+VH+PSGA+EECYV+E+D DK+ +RFIP ENGV+ IDVKFNG HIPGSPFKIR
Sbjct: 2360 AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIR 2419
Query: 2496 VGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCREC 2555
VGE GDPGLVSAYG GLEGG TG +EF+VNT NAG+GALSVTIDGPSKV++DC+EC
Sbjct: 2420 VGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQEC 2479
Query: 2556 PEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVT 2615
PEG+ VTYTPMAPG+YLI+IKYGGP HI GSPFKAKVTGPRL HSLHETS+V V+++T
Sbjct: 2480 PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLT 2539
Query: 2616 KSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGP 2675
K++ + + + +DASKVV +G GLS+A+VGQK+SFTVDCSKAG NM++VGVHGP
Sbjct: 2540 KATCA--PQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGP 2597
Query: 2676 KTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2725
+TPCEE+ VKH+G+R+Y+V+Y +K+KG+Y L+VKWGDE +PGSP++V VP
Sbjct: 2598 RTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2647
>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
Length = 2639
Score = 3331 bits (8637), Expect = 0.0
Identities = 1684/2660 (63%), Positives = 2003/2660 (75%), Gaps = 97/2660 (3%)
Query: 3 NNSGYSDAGLGLGDETD----EMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLT 58
+ +G S AG G D EMP+TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV KR+
Sbjct: 6 SRAGQSAAGAAPGGGVDTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIA 65
Query: 59 DLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSID 118
+LQ DLSDGLRLIALLEVLSQK+M+RK + RP FRQM+LENVSVALEFL+RE IKLVSID
Sbjct: 66 NLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSID 125
Query: 119 SKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPI 178
SKAIVDGNLKLILGLIWTLILHYSISMPMW++E+DE+A+KQTPKQRLLGWIQNK+PQLPI
Sbjct: 126 SKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPI 185
Query: 179 TNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPE 238
TNF+RDWQ G+ALGALVD+CAPGLCPDW++WD ++PV NAREAMQQADDWLG+PQVI PE
Sbjct: 186 TNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPE 245
Query: 239 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHF 298
EIVDPNVDEHSVMTYLSQFPKAKLKPGAP+R K LNPKKA AYGPGIEP GN V + A F
Sbjct: 246 EIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPK-LNPKKARAYGPGIEPTGNMVKKRAEF 304
Query: 299 TVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQN 358
TV+T AG GEVLVY+EDP GH EEAKV NNDK+RT++V YVP+V G HKVTVLFAGQ+
Sbjct: 305 TVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQH 364
Query: 359 IERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQ 418
I +SPFEV V + GDA+KV+A+GPGLEP GN+ANK TYF+I+TAGAGTG+V VVI DP
Sbjct: 365 IAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPM 424
Query: 419 GRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACR 478
G++ TVE LE +GDST+RC+Y+P MEG HTVHV FAG PI RSP+ V V +ACNP+ACR
Sbjct: 425 GQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACR 484
Query: 479 ASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYY 538
A GRGLQPKGVRVKE ADFKV+TKGAGSGELKVTVKGPKG EE VK ++ GDGV+ EYY
Sbjct: 485 AVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKG-EERVKQKDLGDGVYGFEYY 543
Query: 539 PVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIG 598
P+VPG Y+VTITWGG I RSPFEV+V E G QKVRAWGPGLE G VGKSADFVVEAIG
Sbjct: 544 PMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIG 603
Query: 599 TEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHI 658
+VGTLGFS+EGPSQAKIECDDKGDGSCDVRYWP E GEYAVHV+C+ EDIR SPF+A I
Sbjct: 604 DDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADI 663
Query: 659 LPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKV 718
AP D PD+VKA GPGLE TG V+KPAEFT+DA+ GK L++ QD +GCP++ V
Sbjct: 664 RDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALV 723
Query: 719 IPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTG 778
NG+GT+ CSYVP KP+KHT ++SWGGV++P SPFRVNVG GSHP +VKVYGPGV KTG
Sbjct: 724 KDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTG 783
Query: 779 LKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGA 838
LKA+EPTYFTVDC+EAGQGDVSIGIKCAPGVVGPAEADIDFDII+NDNDTFTVKYTP GA
Sbjct: 784 LKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGA 843
Query: 839 GRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAG 898
G YTIMVLFA+Q P SP +KV+PSHDASKVKAEGPGL+RTGVE+GKPTHFTV K AG
Sbjct: 844 GSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG 903
Query: 899 KAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVV 958
K KLDVQF+G KG+ VRD +IID+HD +YTVKYT VQQG + V VTYGGDP+PKSPF V
Sbjct: 904 KGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSV 963
Query: 959 NVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPG 1018
V+P LDLSKIKV GL KV VG++Q F+V ++GAGGQG++ ++ PS +PCK+EPG
Sbjct: 964 AVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPG 1023
Query: 1019 GGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVG 1078
GA+ VR++P EEGPY+V++TYDG PVPGSPF +E V P PSKV A+GPGL+GG G
Sbjct: 1024 LGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAG 1083
Query: 1079 TPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEA 1138
+PA F+IDTKGAGTGGLGLTVEGPCEA++EC DNGDG+C+VSY+PTEPG+Y INILFA+
Sbjct: 1084 SPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADT 1143
Query: 1139 HIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGV 1198
HIPGSPFKA + P FD SKV+ SGPGLER GE F VDCS AG AELTIEI S+AG+
Sbjct: 1144 HIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGL 1203
Query: 1199 KAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGP 1258
AEV I ++ DGT+ ITY P PG YT+TIKYGG PVP FP+++ V+PAVDTSGV+ GP
Sbjct: 1204 PAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGP 1263
Query: 1259 GVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTA 1318
G+E GV RE TTEF+VDAR+LT TGG HV ARV NPSG T+TYV D GDG Y+V+YT
Sbjct: 1264 GIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTP 1323
Query: 1319 YEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGA 1378
YEEG+H V+V YD VP SPF+V VTEGCDP+RVR GPG++ G NK N+FTVETRGA
Sbjct: 1324 YEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGA 1383
Query: 1379 GTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVK 1438
GTGGLGLA+EGPSEAKMSC DNKDGSC+VEYIP+ G Y +N+T+GG +PGSPF+VPV
Sbjct: 1384 GTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVH 1443
Query: 1439 DVVDPGKVKCSGPGLGAG-VRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNG 1497
DV D KVKCSGPGL G VRA +PQ+F VD S+AG APLQV V GP G+ EPV+V DN
Sbjct: 1444 DVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNA 1503
Query: 1498 DGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPAS 1557
DGT TV+Y P+ +GPY+++V Y D+EVPRSPFK+KVLP HDASKV+ASGPGLN +G+PAS
Sbjct: 1504 DGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPAS 1563
Query: 1558 LPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYG 1617
LPVEFTIDA+DAGEGLL VQI DPEGKPKK +I+DN DGTYTV+Y+PD++GRYTI IKYG
Sbjct: 1564 LPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYG 1623
Query: 1618 GDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGK 1677
GDEIP+SP+R+ A+PTGDASKC VT GA +GP IQIG+ETVITVD KAAG+GK
Sbjct: 1624 GDEIPFSPYRVRAVPTGDASKCTVT--------GAGIGPTIQIGEETVITVDTKAAGKGK 1675
Query: 1678 VTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDP 1737
VTCTV TPDG+E+DVDVVEN DGTFDI+YTAP+PGKYVI +RFGGEH+PNSPF V A
Sbjct: 1676 VTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTAL-- 1733
Query: 1738 LPHEEEPSEVPQLRQPYAPPR----PGARPTHWATEEPVVPVEPME-SMLRPFNLVIPFA 1792
++PS P LR P+ G + T WA E P+V V ++ + LRPF+LVIPF
Sbjct: 1734 --AGDQPSVQPPLRSQQLAPQYTYAQGGQQT-WAPERPLVGVNGLDVTSLRPFDLVIPFT 1790
Query: 1793 VQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQF 1852
++KGE+TGEVRMPSGK A+P ITDNKDGT+TVRYAP+E GLH+M I+YD HIPGSPLQF
Sbjct: 1791 IKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQF 1850
Query: 1853 YVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDG 1912
YVD +N HV+AYGPGL+HG+VNKPATFT+ TKDAGEGGLSLA+EGPSKAEI+C DN+DG
Sbjct: 1851 YVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDG 1910
Query: 1913 TCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITES 1972
TC+VSYLP PGDYSI+V+++++H+PGSPFTA++TGDDSMR S L VG++ D+ + I+E+
Sbjct: 1911 TCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISET 1970
Query: 1973 DLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKIL 2032
DLS LTA++ PSG EEPCLLKRL N H+GISF PKE GEH+V V+K+G+HV +SP ++
Sbjct: 1971 DLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVV 2030
Query: 2033 VGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDME 2092
+ SEIGDAS+VRV G+GL EGHTF+ AEFI+DTR+AGYGGL LSIEGPSKVDIN ED+E
Sbjct: 2031 ISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLE 2090
Query: 2093 DGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGS 2152
DGTC+VTYCPTEPG YIINIKFAD+HVPGSPF+VKVTGEGR+KESITRRR+APS+A +GS
Sbjct: 2091 DGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGS 2150
Query: 2153 TCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGET-KREVRVEEST 2211
CDL+LKIP Q ++AQ T + T + E V V+
Sbjct: 2151 HCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKG 2210
Query: 2212 Q-VGGDPFPAVFGDF----LGRERLGSFGSITRQQEG----------EASSQDMTAQVTS 2256
Q V G PF G + R G G + R + G EA + + V
Sbjct: 2211 QHVPGSPFQFTVGPLGEGGAHKVRAGGPG-LERAEAGVPAEFSIWTREAGAGGLAIAVEG 2269
Query: 2257 PSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHK 2316
PS K E + + +D + V +V QE G + V+VK+ +H+P SPF V G A +
Sbjct: 2270 PS-KAEIS-FEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVAS-PSGDARR 2326
Query: 2317 VRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKA--EIAFEDRKDGSCGVSYV 2374
+ PA F++ + G + V PS A E + V ++
Sbjct: 2327 LTVSSLQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFI 2385
Query: 2375 VQEPGDYEVSIKFNDEHIPDSPFVVPVA--SLSDDARRLTVTSLQETGLKVNQPASFAVQ 2432
+E G Y + +KFN HIP SPF + V D ++ G PA F V
Sbjct: 2386 PRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVN 2445
Query: 2433 L-NGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGA-HIPGS 2490
N G + + PS +C + + + + + P G + I +K+ G HI GS
Sbjct: 2446 TSNAGAGALSVTIDGPSKVKMDC---QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGS 2502
Query: 2491 PFKIRV-----------GEQS--------------QAGDPG-------LVSAYGPGLEGG 2518
PFK +V E S Q G PG V A G GL
Sbjct: 2503 PFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKA 2562
Query: 2519 TTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHV------VTYTPMAPGNYL 2572
G S F V+ AG+ L V + GP + C E HV V+Y G Y
Sbjct: 2563 YVGQKSSFTVDCSKAGNNMLLVGVHGP---RTPCEEILVKHVGSRLYSVSYLLKDKGEYT 2619
Query: 2573 IAIKYGGPQHIVGSPFKAKV 2592
+ +K+ G +HI GSP++ V
Sbjct: 2620 LVVKW-GDEHIPGSPYRVVV 2638
Score = 1590 bits (4117), Expect = 0.0
Identities = 967/2450 (39%), Positives = 1351/2450 (55%), Gaps = 194/2450 (7%)
Query: 377 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTF 436
K A GPG+EP GN+ K F + T AG G+V V + DP G ++ +V + + TF
Sbjct: 283 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTF 342
Query: 437 RCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEAC-NPNACRASGRGLQPKGVRVKEVA 495
Y P + G H V V FAG I +SPF V+V ++ + + A G GL+P G +
Sbjct: 343 SVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTT 402
Query: 496 DFKVFTKGAGSGELKVTVKGP---KGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWG 552
F++FT GAG+GE++V ++ P KGT EP ++ GD + C Y P + G + V +T+
Sbjct: 403 YFEIFTAGAGTGEVEVVIQDPMGQKGTVEP-QLEARGDSTYRCSYQPTMEGVHTVHVTFA 461
Query: 553 GYAIPRSPFEVQVSPEAGVQKVRAWGPGLETG--QVGKSADFVVEAIGTEVGTLGFSIEG 610
G IPRSP+ V V RA G GL+ +V ++ADF V G G L +++G
Sbjct: 462 GVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKG 521
Query: 611 PS-QAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDK 669
P + +++ D GDG Y+P PG Y V + ++I SPF + +C K
Sbjct: 522 PKGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKV---GTECGNQK 578
Query: 670 VKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCS 729
V+A+GPGLE G +V K A+F ++A G L + I+ GDG+
Sbjct: 579 VRAWGPGLE--GGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECD--DKGDGSCDVR 634
Query: 730 YVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGS---HPERVKVYGPGVEKTGLKANEPTY 786
Y P + ++ + + ++ SPF ++ + HP+RVK GPG+EKTG+ N+P
Sbjct: 635 YWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAE 694
Query: 787 FTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVL 846
FTVD G+ + + ++ G P EA + N N T++ Y P ++T MV
Sbjct: 695 FTVDAKHGGKAPLRVQVQDNEGC--PVEALVK----DNGNGTYSCSYVPRKPVKHTAMVS 748
Query: 847 FANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQF 906
+ IP SPF + V +KVK GPG+ +TG++ +PT+FTV AG+ + +
Sbjct: 749 WGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGI 808
Query: 907 ------AGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV 960
G A+ ++ DF+II N + ++TVKYT G+ + V + P SP V V
Sbjct: 809 KCAPGVVGPAEADI--DFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKV 866
Query: 961 APPLDLSKIKVQG---LNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEP 1017
P D SK+K +G + V +G+ F+VN + AG +G+LDV+ + ++ ++
Sbjct: 867 EPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAG-KGKLDVQFSGLTKGDAVRDVDI 925
Query: 1018 GGGAE-AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL 1076
+ V+Y P ++GP V++TY G P+P SPF+V D SK+ G G K
Sbjct: 926 IDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVD- 984
Query: 1077 VGTPAPFSIDTKGAG-TGGLGLTVEGPCEAKIECQDN---GDGSCAVSYLPTEPGEYTIN 1132
VG F++ +KGAG G + + GP A + C+ G + V +LP E G Y +
Sbjct: 985 VGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVE 1044
Query: 1133 ILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEI 1192
+ + +PGSPF PSKV+A GPGL+ G G A FT+D AG L + +
Sbjct: 1045 VTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTV 1104
Query: 1193 LSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSG 1252
+ E L +N DGT ++Y P PG Y I I + +P P + HV P D S
Sbjct: 1105 EGPCEAQLECL--DNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASK 1162
Query: 1253 VKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTY 1312
VK SGPG+E EV +F VD S G +T + + +G + Y+ D+GDGT+
Sbjct: 1163 VKCSGPGLE-RATAGEVG-QFQVDCSS---AGSAELTIEICSEAGLPAEVYIQDHGDGTH 1217
Query: 1313 RVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEG-GLVNKAN-R 1370
+ Y G + V + Y VP P ++ V D + V+ +GPG+EG G+ +A
Sbjct: 1218 TITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTE 1277
Query: 1371 FTVETRG-AGTGG--LGLAIEGPSE--AKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGG 1425
F+V+ R TGG + + PS + +D DG VEY P+ G + V++T+ G
Sbjct: 1278 FSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDG 1337
Query: 1426 RPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPT 1485
P+P SPF+VPV + DP +V+ GPG+ +G + P FTV+ AG L +AV GP+
Sbjct: 1338 SPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNK-PNKFTVETRGAGTGGLGLAVEGPS 1396
Query: 1486 GVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRAS 1545
+ DN DG+ +V Y P G Y++ V Y +VP SPFK+ V DASKV+ S
Sbjct: 1397 EAK--MSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCS 1454
Query: 1546 GPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPD 1605
GPGL+ + A+LP F +D AG L V++ P+G + ++ DN DGT TV+Y+P
Sbjct: 1455 GPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPS 1514
Query: 1606 MSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETV 1665
G Y+I++ YG +E+P SPF++ LPT DASK V G GL P
Sbjct: 1515 REGPYSISVLYGDEEVPRSPFKVKVLPTHDASK----VKASGPGLNTTGVPA---SLPVE 1567
Query: 1666 ITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHI 1725
T+DAK AGEG + ++ P+G + +NHDGT+ + Y G+Y I I++GG+ I
Sbjct: 1568 FTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEI 1627
Query: 1726 PNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPF 1785
P SP+ V A +P + G PT EE V+ V+
Sbjct: 1628 PFSPYRVRA---VPTGDASK--------CTVTGAGIGPTIQIGEETVITVDTK------- 1669
Query: 1786 NLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHI 1845
A KG++T V P G ++ +N+DGT + Y + G + + +++ G H+
Sbjct: 1670 ------AAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHV 1723
Query: 1846 PGSPLQFYVDAINSRHVSAYGP---------------------------GLSHGMVNKPA 1878
P SP Q V A+ S P G++ V
Sbjct: 1724 PNSPFQ--VTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLR 1781
Query: 1879 TFTIV---TKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDK 1935
F +V T GE + + A+ T DNKDGT TV Y P+ G + + +R+D+
Sbjct: 1782 PFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNM 1841
Query: 1936 HIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLK-----ITESDLSQ--LTASIRAPSGNE 1988
HIPGSP + + + G + V K + D + L+ +I PS E
Sbjct: 1842 HIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAE 1901
Query: 1989 EPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWG 2048
C + + +S+ P G++ + V+ + +HV SPF V + S ++V
Sbjct: 1902 ISCTDNQ--DGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGS 1959
Query: 2049 KGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINC--EDMEDGTCKVTYCPTEPG 2106
A+ ++ L ++ PS + C + + +G +++ P E G
Sbjct: 1960 ----------AADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETG 2009
Query: 2107 TYIINIKFADKHVPGSPFTV-------------KVTGEGRMKESITRRRQAPSIATIGST 2153
+++++K +HV SP V +V+G+G + +
Sbjct: 2010 EHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGY 2069
Query: 2154 CDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQV 2213
L+L I G ++ + T R T G ++ + V
Sbjct: 2070 GGLSLSIEGP-----------SKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQ-HV 2117
Query: 2214 GGDPFPA-VFGDFLGRERLGSFGSITRQQEG-----------------EASSQDMTAQVT 2255
G PF V G+ +E SITR++ E S QDMTAQVT
Sbjct: 2118 PGSPFSVKVTGEGRVKE------SITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVT 2171
Query: 2256 SPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAH 2315
SPSGK AEIVEGE+ Y +RFVP EMG HTV+VKY+GQHVPGSPFQFTVGPLGEGGAH
Sbjct: 2172 SPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAH 2231
Query: 2316 KVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVV 2375
KVRAGG GLER AGVPAEFSIWTREAGAGGL+IAVEGPSKAEI+FEDRKDGSCGV+YVV
Sbjct: 2232 KVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVV 2291
Query: 2376 QEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNG 2435
QEPGDYEVS+KFN+EHIPDSPFVVPVAS S DARRLTV+SLQE+GLKVNQPASFAV LNG
Sbjct: 2292 QEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNG 2351
Query: 2436 ARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIR 2495
A+G IDA+VH+PSGA+EECYV+E+D DK+ +RFIP ENGV+ IDVKFNG HIPGSPFKIR
Sbjct: 2352 AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIR 2411
Query: 2496 VGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCREC 2555
VGE GDPGLVSAYG GLEGG TG +EF+VNT NAG+GALSVTIDGPSKV++DC+EC
Sbjct: 2412 VGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQEC 2471
Query: 2556 PEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVT 2615
PEG+ VTYTPMAPG+YLI+IKYGGP HI GSPFKAKVTGPRL HSLHETS+V V+++T
Sbjct: 2472 PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLT 2531
Query: 2616 KSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGP 2675
K++ + + + +DASKVV +G GLS+A+VGQK+SFTVDCSKAG NM++VGVHGP
Sbjct: 2532 KATCA--PQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGP 2589
Query: 2676 KTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2725
+TPCEE+ VKH+G+R+Y+V+Y +K+KG+Y L+VKWGDE +PGSP++V VP
Sbjct: 2590 RTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2639
>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
sapiens]
Length = 2602
Score = 3205 bits (8310), Expect = 0.0
Identities = 1620/2647 (61%), Positives = 1958/2647 (73%), Gaps = 121/2647 (4%)
Query: 21 MPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQK 80
MP TEKDLAEDAPWKKIQQNTFTRWCNEHLKCV KR+ +LQ DLSDGLRLIALLEVLSQK
Sbjct: 1 MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQK 60
Query: 81 RMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILH 140
RMYRK+H RP FRQM+LENVSVALEFL+RE IKLVSIDSKAIVDGNLKLILGL+WTLILH
Sbjct: 61 RMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILH 120
Query: 141 YSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAP 200
YSISMP+WEDE D+DA+KQTPKQRLLGWIQNK+P LPITNFN++WQDGKALGALVD+CAP
Sbjct: 121 YSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAP 180
Query: 201 GLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKA 260
GLCPDWE+WDP +PV+NAREAMQQADDWLGVPQVI PEEI+ P+VDEHSVMTYLSQFPKA
Sbjct: 181 GLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKA 240
Query: 261 KLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGH 320
KLKPGAP++ K LNPKKA AYG GIEP GN V QPA FTV T+ AG G+V+V++EDPEG+
Sbjct: 241 KLKPGAPLKPK-LNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGN 299
Query: 321 TEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSA 380
EEA+V P++DK++TY+V Y+PKV GLHKVTVLFAGQ+I +SPFEV+V A GDA+KV+A
Sbjct: 300 KEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTA 359
Query: 381 RGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTY 440
+GPGLE VGN+ANKPTYFDIYTAGAG GD+ V + DPQG+ +TVE+ +EDKG+ +RC Y
Sbjct: 360 KGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGK-NTVELLVEDKGNQVYRCVY 418
Query: 441 RPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVF 500
+P GPH V + FAG I +SPF V V EACNPNACRASGRGLQPKGVR++E DFKV
Sbjct: 419 KPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVD 478
Query: 501 TKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSP 560
TK AGSGEL VT+KGPKG EE VK ++ DGV+ EYYP PG+Y + ITWGG+ IP+SP
Sbjct: 479 TKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSP 538
Query: 561 FEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDD 620
FEVQV PEAG+QKVRAWGPGL G VG+SADFVVE+IG+EVG+LGF+IEGPSQAKIE +D
Sbjct: 539 FEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYND 598
Query: 621 KGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPT 680
+ DGSCDV+YWP EPGEYAVH++CDDEDI+DSP++A I PA PD V+A+GPGLE +
Sbjct: 599 QNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKS 658
Query: 681 GCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTI 740
GCIV+ AEFT+D + AGK LK++AQD +G IDI++ DGT+ CSY P K IKHTI
Sbjct: 659 GCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTI 718
Query: 741 IISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVS 800
+ WGGVN+P SP+RVN+G+GSHP++VKV+GPGVE++GLKANEPT+FTVDC+EAG+GDVS
Sbjct: 719 AVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVS 778
Query: 801 IGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIK 860
+GIKC V+ E D+DFDII N NDTFTVKY PP AGRYTI VLFA+QEIPASPF +K
Sbjct: 779 VGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVK 838
Query: 861 VDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQFAGTAKGEVVRDFEI 920
VDPSHDASKVKAEGPGL++ GVE GKPTHFTV TKGAGKA L+VQF G+ V+D +I
Sbjct: 839 VDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDI 898
Query: 921 IDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAV 980
IDN+DYS+TVKYT QQGNM V VTYGGDP+PKSPF V VA PLDLSKIK+ GL ++V V
Sbjct: 899 IDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEV 958
Query: 981 GQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDI 1040
G++Q F+V+TRGAGGQG+LDV + SPSR+ +PC + P G E +++P EEG Y VD+
Sbjct: 959 GKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDV 1018
Query: 1041 TYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVE 1100
TYDGHPVPGSP+ VE LPPDPSKV A+GPGL+GGLVG PA F+IDTKGAGTGGLGLTVE
Sbjct: 1019 TYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVE 1078
Query: 1101 GPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRA 1160
GPCEAKIEC DNGDG+C+VSYLPT+PGEY +NILF E HIPGSPFKA I FDPSKV A
Sbjct: 1079 GPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVA 1138
Query: 1161 SGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAF 1220
SGPGLE GKVGEA +VDCSEAG L +E +SD+G KAEV I NN DGTY +TY P
Sbjct: 1139 SGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLT 1198
Query: 1221 PGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGVEPHGVLREVTTEFTVDARSL 1280
G YT+T+KYGG VP FP RV V+PAVDTS +KV GPG+E V RE TT+FTVD+R L
Sbjct: 1199 AGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPL 1258
Query: 1281 TATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPF 1340
T GG+H+ A + NPSGA T+ +VTDN DGTY+V+YT +E+G+H+VEV YD+V +P SPF
Sbjct: 1259 TQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPF 1318
Query: 1341 RVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDN 1400
+V VTEGC P+RV+A GPGL+ NK N FTV TRGAG GGLG+ +EGPSE+K++C+DN
Sbjct: 1319 KVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDN 1378
Query: 1401 KDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRAR 1460
KDGSC+ EYIPF PGDYDVNIT+GG IPGSPFRVPVKDVVDP KVK +GPGLG+GVRAR
Sbjct: 1379 KDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRAR 1438
Query: 1461 VPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYA 1520
V Q+FTVD S+AG APL+V VLGP G+ EPV V DNGDGTHTV YTP+ +GPY V+VKYA
Sbjct: 1439 VLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYA 1498
Query: 1521 DQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILD 1580
D+E+PRSPFK+KVLP +DASKV ASGPGL++ G+PASLPV+F IDARDAGEGLL VQI D
Sbjct: 1499 DEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITD 1558
Query: 1581 PEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCL 1640
EGKPK+A + DN DGTY V+Y+PD +GRY I + YGGD+IP SP+RI A TGDASKCL
Sbjct: 1559 QEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCL 1618
Query: 1641 VTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDG 1700
T G + ++ G+E VDAK AG+GKVTCTV TPDG E + DV+EN DG
Sbjct: 1619 AT--------GPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDG 1670
Query: 1701 TFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQ-PYAPPRP 1759
T+DI+YTA +PG YVI +RFGG IPNSPF V+A D EV + + P P
Sbjct: 1671 TYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD--------GEVTAVEEAPVNACPP 1722
Query: 1760 GARPTHWATEEPVVPVEPMESM-LRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNK 1818
G RP W TEE VPV M + +PF+LVIPFAV+KGE+TGEV MPSGKTA P I DNK
Sbjct: 1723 GFRP--WVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNK 1780
Query: 1819 DGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPA 1878
DGT+TVRYAPTE GLH+M IKY G+HIP SPLQFYV+ NS VSAYGPGL +G+ NK A
Sbjct: 1781 DGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTA 1840
Query: 1879 TFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIP 1938
TFTIVT+DAGEGGL LA+EGPSKAEI+C DNKDGTCTV+YLPT PGDYSI+V+++DKHIP
Sbjct: 1841 TFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIP 1900
Query: 1939 GSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTASIRAPSGNEEPCLLKRLPN 1998
GSPFTAKIT DDS R SQ+ +G++ D L I+E+DLS LTASI+APSG +EPCLLKRLPN
Sbjct: 1901 GSPFTAKIT-DDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPN 1959
Query: 1999 RHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQ 2058
HIGISF P+EVGEH+VS++K+G HV NSP I+V SEIGDA + +V+G+GLSEG TF+
Sbjct: 1960 NHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFE 2019
Query: 2059 VAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKH 2118
+++FIVDTR+AGYGG+ L++EGPSKVDI ED+EDGTCKV+Y PT PG YI++ KFAD+H
Sbjct: 2020 MSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEH 2079
Query: 2119 VPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTF 2178
VPGSPFTVK++GEGR+KESITR +APS+AT+GS CDLNLKIP +++ +
Sbjct: 2080 VPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIP-----EINSSDMSAHVT 2134
Query: 2179 TRSSHTYTRTERTEISKTRGGETKREVRVE----------ESTQVGGDPFPAVFGDF--- 2225
+ S TE + + R V E V G PF G
Sbjct: 2135 SPSGRV---TEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEG 2191
Query: 2226 -LGRERLGSFGSITRQQEG----------EASSQDMTAQVTSPSGKVEAAEIV--EGEDS 2272
+ R G G + R + G EA + ++ V PS AEI + ++
Sbjct: 2192 GAHKVRAGGPG-LERGEAGVPAEFSIWTREAGAGGLSIAVEGPS----KAEITFDDHKNG 2246
Query: 2273 AYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQF-TVGPLGEGGAHKVRA-GGTGLERGVAG 2330
+ V ++ QE G + V++K+ +H+P SP+ + P + V + +GL+
Sbjct: 2247 SCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLK---VN 2303
Query: 2331 VPAEFSIWTREAGAGGLSIAVEGPSKA--EIAFEDRKDGSCGVSYVVQEPGDYEVSIKFN 2388
PA F+I A G + V PS A E + + V ++ E G + + +KFN
Sbjct: 2304 QPASFAIRLNGA-KGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFN 2362
Query: 2389 DEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVN----QPASFAVQLNGARGVIDARV 2444
H+ SPF V V A + S TGL+ Q F G + +
Sbjct: 2363 GSHVVGSPFKVRVGE-PGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTI 2421
Query: 2445 HTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGA-HIPGSPFKIRVGEQ---- 2499
PS +C + + + + + P G + I VK+ G HI GSPFK +V Q
Sbjct: 2422 EGPSKVKMDC---QETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVS 2478
Query: 2500 ----------------------------SQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTL 2531
+ D V++ G GL G S F+V+
Sbjct: 2479 PGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCS 2538
Query: 2532 NAGSGALSVTIDGPSKVQLDCRECPEGHV------VTYTPMAPGNYLIAIKYGGPQHIVG 2585
AGS L + + GP+ C E HV VTY G+Y++A+K+ G +HI G
Sbjct: 2539 KAGSNMLLIGVHGPT---TPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKW-GEEHIPG 2594
Query: 2586 SPFKAKV 2592
SPF V
Sbjct: 2595 SPFHVTV 2601
Score = 1523 bits (3944), Expect = 0.0
Identities = 954/2440 (39%), Positives = 1334/2440 (54%), Gaps = 184/2440 (7%)
Query: 377 KVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTF 436
K A G G+EP GN+ +P F + T AG GDV V + DP+G ++ +V + + T+
Sbjct: 256 KARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTY 315
Query: 437 RCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEAC-NPNACRASGRGLQPKGVRVKEVA 495
Y P + G H V V FAG I++SPF V V +A + + A G GL+ G +
Sbjct: 316 SVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPT 375
Query: 496 DFKVFTKGAGSGELKVTVKGPKGTEE-PVKVREAGDGVFECEYYPVVPGKYVVTITWGGY 554
F ++T GAG G++ V V+ P+G + V + G+ V+ C Y P+ PG +VV I + G
Sbjct: 376 YFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGD 435
Query: 555 AIPRSPFEVQVSPEAGVQKVRAWGPGLETG--QVGKSADFVVEAIGTEVGTLGFSIEGPS 612
IP+SPF VQV RA G GL+ ++ ++ DF V+ G LG +++GP
Sbjct: 436 TIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPK 495
Query: 613 --QAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKV 670
+ ++ D DG Y+P+ PG Y++ + I SPF + P+ KV
Sbjct: 496 GLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQV---GPEAGMQKV 552
Query: 671 KAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSY 730
+A+GPGL G IV + A+F +++ + G L + I+ DG+ Y
Sbjct: 553 RAWGPGLH--GGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYN--DQNDGSCDVKY 608
Query: 731 VPTKPIKHTIIISWGGVNVPKSPFRVNVGE---GSHPERVKVYGPGVEKTGLKANEPTYF 787
P +P ++ + I ++ SP+ + G +P+ V+ YGPG+EK+G N F
Sbjct: 609 WPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEF 668
Query: 788 TVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLF 847
TVD +AG+ + I + G ID + + T+ YTP A ++TI V++
Sbjct: 669 TVDPKDAGKAPLKIFAQDGEG------QRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVW 722
Query: 848 ANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQFA 907
IP SP+ + + KVK GPG+ R+G++ +PTHFTV AG+ + V
Sbjct: 723 GGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIK 782
Query: 908 GTAK----GEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPP 963
A+ E DF+II N + ++TVKY G + V + +P SPF V V P
Sbjct: 783 CDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPS 842
Query: 964 LDLSKIKVQGLN-SKVAV--GQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG 1020
D SK+K +G SK V G+ F+V T+GAG + L+V+ SP L+
Sbjct: 843 HDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAG-KAPLNVQFNSPLPGDAVKDLDIIDN 901
Query: 1021 AE-AQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGL-VG 1078
+ + V+Y P ++G +V +TY G P+P SPF V P D SK+ G L+ + VG
Sbjct: 902 YDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNG--LENRVEVG 959
Query: 1079 TPAPFSIDTKGAG-TGGLGLTVEGPCEAKIEC---QDNGDGSCAVSYLPTEPGEYTINIL 1134
F++DT+GAG G L +T+ P + C G + ++P E G Y +++
Sbjct: 960 KDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVT 1019
Query: 1135 FAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILS 1194
+ +PGSP+ DPSKV+A GPGLE G VG+ A FT+D AG L + +
Sbjct: 1020 YDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTV-- 1077
Query: 1195 DAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVK 1254
+ +A++ +N DGT ++Y P PG Y + I + +P P + ++ D S V
Sbjct: 1078 EGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVV 1137
Query: 1255 VSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRV 1314
SGPG+E HG + E +VD + G + ++ SG K + + +N DGTY V
Sbjct: 1138 ASGPGLE-HGKVGEAGL-LSVDC---SEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAV 1192
Query: 1315 QYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNK--ANRFT 1372
Y G++ + + Y VP P RV V D +R++ FGPG+EG V + FT
Sbjct: 1193 TYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFT 1252
Query: 1373 VETRG---AGTGGLGLAIEGPSEAKMSC--KDNKDGSCTVEYIPFTPGDYDVNITFGGRP 1427
V++R G + I PS A C DN DG+ VEY PF G + V +T+ P
Sbjct: 1253 VDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVP 1312
Query: 1428 IPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGV 1487
IP SPF+V V + P +V+ GPGL + P FTV AG L + V GP+
Sbjct: 1313 IPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNK-PNVFTVVTRGAGIGGLGITVEGPS-- 1369
Query: 1488 AEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGP 1547
+ RDN DG+ + Y P G Y V + Y +P SPF++ V D SKV+ +GP
Sbjct: 1370 ESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGP 1429
Query: 1548 GLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMS 1607
GL SG+ A + FT+D+ AG L V++L P G + N+ DNGDGT+TV+Y P
Sbjct: 1430 GLG-SGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQE 1488
Query: 1608 GRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVIT 1667
G Y +++KY +EIP SPF++ LPT DASK V+ G GL + P
Sbjct: 1489 GPYMVSVKYADEEIPRSPFKVKVLPTYDASK----VTASGPGLSSYGVPA---SLPVDFA 1541
Query: 1668 VDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPN 1727
+DA+ AGEG + ++ +G V +N DGT+ + Y + G+Y+I + +GG+ IP
Sbjct: 1542 IDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPL 1601
Query: 1728 SPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNL 1787
SP+ + A ++ + A PG T EE V+ +
Sbjct: 1602 SPYRIRA----------TQTGDASKCLATG-PGIASTVKTGEEVGFVVDAKTA------- 1643
Query: 1788 VIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPG 1847
KG++T V P G A ++ +N+DGT + Y + G + + +++ G IP
Sbjct: 1644 ------GKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPN 1697
Query: 1848 SPLQFY-----VDAINSRHVSAYGPGLS--------------HGMVNKPATFTIVTKDAG 1888
SP V A+ V+A PG +G+ KP ++
Sbjct: 1698 SPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDL-VIPFAVR 1756
Query: 1889 EGGLSLAVEGPSKAEITCK--DNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKI 1946
+G ++ V PS T + DNKDGT TV Y PT G + + +++ HIP SP +
Sbjct: 1757 KGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYV 1816
Query: 1947 TGDDSMRTSQLNVGTSTDVSLK-----ITESDLSQ--LTASIRAPSGNEEPCLLKRLPNR 1999
+S S G V+ K I D + L +I PS E C+ + +
Sbjct: 1817 NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DG 1874
Query: 2000 HIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQV 2059
+++ P G++ + V+ + KH+ SPF +K+ + S+
Sbjct: 1875 TCTVTYLPTLPGDYSILVKYNDKHIPGSPF-----------TAKITDDSRRCSQVKLGSA 1923
Query: 2060 AEFIVDTRNAGYGGLGLSIEGPSKVDINC--EDMEDGTCKVTYCPTEPGTYIINIKFADK 2117
A+F++D L SI+ PS D C + + + +++ P E G ++++IK
Sbjct: 1924 ADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGN 1983
Query: 2118 HVPGSPFTVKVT-----------------GEGR---MKESITRRRQAP----SIATIG-S 2152
HV SP ++ V EGR M + I R A S+A G S
Sbjct: 1984 HVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPS 2043
Query: 2153 TCDLNLK------IPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVR 2206
D+ + ++F V ++ F H +IS E R
Sbjct: 2044 KVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFA-DEHVPGSPFTVKISG--------EGR 2094
Query: 2207 VEES-TQVGGDPFPAVFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAE 2265
V+ES T+ P A G + E +S DM+A VTSPSG+V AE
Sbjct: 2095 VKESITRTSRAPSVATVGSICD----------LNLKIPEINSSDMSAHVTSPSGRVTEAE 2144
Query: 2266 IVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLE 2325
IV +++ VRFVPQEMG HTV+VKYRGQHV GSPFQFTVGPLGEGGAHKVRAGG GLE
Sbjct: 2145 IVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLE 2204
Query: 2326 RGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSI 2385
RG AGVPAEFSIWTREAGAGGLSIAVEGPSKAEI F+D K+GSCGVSY+ QEPG+YEVSI
Sbjct: 2205 RGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSI 2264
Query: 2386 KFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVH 2445
KFNDEHIP+SP++VPV + SDDARRLTV SLQE+GLKVNQPASFA++LNGA+G IDA+VH
Sbjct: 2265 KFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVH 2324
Query: 2446 TPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDP 2505
+PSGAVEEC+VSEL+ DK+ +RFIPHENGVH+IDVKFNG+H+ GSPFK+RVGE QAG+P
Sbjct: 2325 SPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNP 2384
Query: 2506 GLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTP 2565
LVSAYG GLEGGTTG+ SEF +NT AG G LSVTI+GPSKV++DC+E PEG+ V YTP
Sbjct: 2385 ALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTP 2444
Query: 2566 MAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSY 2625
MAPGNYLI++KYGGP HIVGSPFKAKVTG RL S +ETS++LVE+VT+SS+ + Y
Sbjct: 2445 MAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTE--TCY 2502
Query: 2626 SSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVK 2685
S+IPK SSDASKV ++G GLS+AFVGQK+SF VDCSKAG+NM+++GVHGP TPCEEV +K
Sbjct: 2503 SAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMK 2562
Query: 2686 HMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 2725
H+GN+ YNVTY VKE+GDY+L VKWG+E +PGSPF V VP
Sbjct: 2563 HVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2602
Score = 140 bits (352), Expect = 2e-32
Identities = 126/438 (28%), Positives = 195/438 (44%), Gaps = 64/438 (14%)
Query: 2298 PGSPFQFTVGPLGEGGAHKVRAGGTGLER--GVAGVPAEFSIWTREAGAGGLSIAVEGP- 2354
PG+P + + P K RA G G+E + PA+F++ T AG G + + VE P
Sbjct: 244 PGAPLKPKLNP------KKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPE 297
Query: 2355 ---SKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRL 2411
+A++ + K+ + V Y+ + G ++V++ F +HI SPF V V DA ++
Sbjct: 298 GNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKV 357
Query: 2412 TV--TSLQETGLKVNQPASFAVQLNGAR-GVIDARVHTPSGA-VEECYVSELDSDKHTIR 2467
T L+ G N+P F + GA G I V P G E V + + +
Sbjct: 358 TAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCV 417
Query: 2468 FIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLE--GGTTGVSSE 2525
+ P + G H + + F G IP SPF ++VGE A +P A G GL+ G +++
Sbjct: 418 YKPMQPGPHVVKIFFAGDTIPKSPFVVQVGE---ACNPNACRASGRGLQPKGVRIRETTD 474
Query: 2526 FIVNTLNAGSGALSVTIDGPSKVQ--LDCRECPEG-HVVTYTPMAPGNYLIAIKYGGPQH 2582
F V+T AGSG L VT+ GP ++ + ++ +G + Y P PG Y IAI +GG H
Sbjct: 475 FKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGG-HH 533
Query: 2583 IVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRG 2642
I SPF+ +V GP + KV G
Sbjct: 534 IPKSPFEVQV-GP------------------------------------EAGMQKVRAWG 556
Query: 2643 PGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKG 2702
PGL VG+ F V+ + + + GP E ++ G+ +V Y KE G
Sbjct: 557 PGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGS--CDVKYWPKEPG 614
Query: 2703 DYILIVKWGDESVPGSPF 2720
+Y + + DE + SP+
Sbjct: 615 EYAVHIMCDDEDIKDSPY 632
Score = 75.1 bits (183), Expect = 9e-13
Identities = 62/247 (25%), Positives = 105/247 (42%), Gaps = 54/247 (21%)
Query: 2488 PGSPFKIRVGEQSQAGDPGLVSAYGPGLE--GGTTGVSSEFIVNTLNAGSGALSVTIDGP 2545
PG+P K ++ +P AYG G+E G ++F V+T++AG G + V ++ P
Sbjct: 244 PGAPLKPKL-------NPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDP 296
Query: 2546 SKVQLDCRECPEG-----HVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGG 2600
+ + + P+ + V Y P G + + + + G QHI SPF+
Sbjct: 297 EGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAG-QHISKSPFEV---------- 345
Query: 2601 HSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQA--FVGQKNSFTV 2658
S+ K DASKV +GPGL + F +
Sbjct: 346 --------------------------SVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDI 379
Query: 2659 DCSKAGTNMMMVGVHGPKTP-CEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPG 2717
+ AG + V V P+ E+ V+ GN+VY Y + G +++ + + +++P
Sbjct: 380 YTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPK 439
Query: 2718 SPFKVKV 2724
SPF V+V
Sbjct: 440 SPFVVQV 446
>gi|239755812 PREDICTED: similar to spectrin, beta, non-erythrocytic
2 [Homo sapiens]
Length = 158
Score = 192 bits (489), Expect = 3e-48
Identities = 93/120 (77%), Positives = 106/120 (88%)
Query: 82 MYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 141
MY K+H RP FRQM+L+NVSVALEFL+R+ IKLVSIDSKA VDGNLKLILGL+WTLIL Y
Sbjct: 1 MYLKYHQRPTFRQMQLKNVSVALEFLDRDSIKLVSIDSKATVDGNLKLILGLVWTLILRY 60
Query: 142 SISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPG 201
SIS P+ EDE D+DA+KQ KQRLLGWIQNKVP LPITNF+++WQD KAL ALVD+CAPG
Sbjct: 61 SISTPVCEDEGDDDAKKQMRKQRLLGWIQNKVPYLPITNFSQNWQDSKALRALVDSCAPG 120
>gi|4557241 actinin, alpha 3 [Homo sapiens]
Length = 901
Score = 164 bits (416), Expect = 8e-40
Identities = 94/254 (37%), Positives = 151/254 (59%), Gaps = 21/254 (8%)
Query: 11 GLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRL 70
G G G+ ++ ++DL D W+K Q+ TFT WCN HL+ G ++ +++ D +GL+L
Sbjct: 20 GGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKL 79
Query: 71 IALLEVLSQKRMYRKFHPRPNFRQM---KLENVSVALEFLEREHIKLVSIDSKAIVDGNL 127
+ LLEV+S +R+ PRP+ +M K+ NV+ AL+F+ + +KLVSI ++ IVDGNL
Sbjct: 80 MLLLEVISGERL-----PRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNL 134
Query: 128 KLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVP---QLPITNFNRD 184
K+ LG+IWT+IL ++I D + + K+ LL W Q K + + NF+
Sbjct: 135 KMTLGMIWTIILRFAI--------QDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTS 186
Query: 185 WQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVD-P 243
W+DG AL AL+ P L D+ + P+ N A + A+ +L +P+++ E+IV+ P
Sbjct: 187 WKDGLALCALIHRHRPDLI-DYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTP 245
Query: 244 NVDEHSVMTYLSQF 257
DE ++MTY+S F
Sbjct: 246 KPDEKAIMTYVSCF 259
>gi|12025678 actinin, alpha 4 [Homo sapiens]
Length = 911
Score = 160 bits (406), Expect = 1e-38
Identities = 94/262 (35%), Positives = 148/262 (56%), Gaps = 21/262 (8%)
Query: 6 GYSDAGLG------LGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTD 59
G S AG G +GD + ++DL D W+K Q+ TFT WCN HL+ G ++ +
Sbjct: 14 GPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIEN 73
Query: 60 LQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDS 119
+ D DGL+L+ LLEV+S +R+ + R R K+ NV+ AL+F+ + +KLVSI +
Sbjct: 74 IDEDFRDGLKLMLLLEVISGERLPKP--ERGKMRVHKINNVNKALDFIASKGVKLVSIGA 131
Query: 120 KAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQL 176
+ IVDGN K+ LG+IWT+IL ++I D + + K+ LL W Q K +
Sbjct: 132 EEIVDGNAKMTLGMIWTIILRFAI--------QDISVEETSAKEGLLLWCQRKTAPYKNV 183
Query: 177 PITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIA 236
+ NF+ W+DG A AL+ P L +++ + PV N A + A+ +L +P+++
Sbjct: 184 NVQNFHISWKDGLAFNALIHRHRPELI-EYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLD 242
Query: 237 PEEIVD-PNVDEHSVMTYLSQF 257
E+IV+ DE ++MTY+S F
Sbjct: 243 AEDIVNTARPDEKAIMTYVSSF 264
>gi|4501893 actinin, alpha 2 [Homo sapiens]
Length = 894
Score = 158 bits (399), Expect = 8e-38
Identities = 89/240 (37%), Positives = 145/240 (60%), Gaps = 21/240 (8%)
Query: 25 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYR 84
++DL D W+K Q+ TFT WCN HL+ G ++ +++ D +GL+L+ LLEV+S +R+
Sbjct: 27 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERL-- 84
Query: 85 KFHPRPNFRQM---KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHY 141
P+P+ +M K+ NV+ AL+++ + +KLVSI ++ IVDGN+K+ LG+IWT+IL +
Sbjct: 85 ---PKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRF 141
Query: 142 SISMPMWEDEDDEDARKQTPKQRLLGWIQNKVP---QLPITNFNRDWQDGKALGALVDNC 198
+I D + + K+ LL W Q K + I NF+ W+DG L AL+
Sbjct: 142 AI--------QDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRH 193
Query: 199 APGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVD-PNVDEHSVMTYLSQF 257
P L D+ + + P+ N AM+ A+ L +P+++ E+IV+ P DE ++MTY+S F
Sbjct: 194 RPDLI-DYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCF 252
>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
Length = 887
Score = 154 bits (388), Expect = 1e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 25 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYR 84
++DL D W+K Q+ TFT WCN HL+ G ++ +++ D DGL+L+ LLEV+S +R+ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 85 KFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 144
R R K+ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 145 MPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPG 201
D + + K+ LL W Q K + I NF+ W+DG AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 202 LCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIV-DPNVDEHSVMTYLSQF 257
L D+ + P+ N A A+ +L +P+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
Length = 914
Score = 154 bits (388), Expect = 1e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 25 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYR 84
++DL D W+K Q+ TFT WCN HL+ G ++ +++ D DGL+L+ LLEV+S +R+ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 85 KFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 144
R R K+ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 145 MPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPG 201
D + + K+ LL W Q K + I NF+ W+DG AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 202 LCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIV-DPNVDEHSVMTYLSQF 257
L D+ + P+ N A A+ +L +P+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
Length = 892
Score = 154 bits (388), Expect = 1e-36
Identities = 87/237 (36%), Positives = 137/237 (57%), Gaps = 15/237 (6%)
Query: 25 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYR 84
++DL D W+K Q+ TFT WCN HL+ G ++ +++ D DGL+L+ LLEV+S +R+ +
Sbjct: 20 DRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAK 79
Query: 85 KFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSIS 144
R R K+ NV+ AL+F+ + +KLVSI ++ IVDGN+K+ LG+IWT+IL ++I
Sbjct: 80 P--ERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAI- 136
Query: 145 MPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPG 201
D + + K+ LL W Q K + I NF+ W+DG AL+ P
Sbjct: 137 -------QDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPE 189
Query: 202 LCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIV-DPNVDEHSVMTYLSQF 257
L D+ + P+ N A A+ +L +P+++ E+IV DE ++MTY+S F
Sbjct: 190 LI-DYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSF 245
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 147 bits (371), Expect = 1e-34
Identities = 87/227 (38%), Positives = 129/227 (56%), Gaps = 14/227 (6%)
Query: 37 IQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMK 96
+Q+ TFT+W N HL V R+TDL +DL DG LI LLEVLS + + P+P +M+
Sbjct: 55 VQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEML-----PKPTKGKMR 109
Query: 97 ---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDD 153
LENV AL+FL+ + + L ++ S IVDGN +L+LGLIWT+IL + I + + ++
Sbjct: 110 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEG 169
Query: 154 EDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWD 210
+ R + K LL W Q K P + +TNF W+DG A AL+ P L D++
Sbjct: 170 RETR--SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLI-DFDKLK 226
Query: 211 PNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQF 257
+ N A A+ LG+ ++ PE++ N DE S++TY+ F
Sbjct: 227 DSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAF 273
>gi|67782319 spectrin beta isoform b [Homo sapiens]
Length = 2137
Score = 147 bits (371), Expect = 1e-34
Identities = 87/227 (38%), Positives = 129/227 (56%), Gaps = 14/227 (6%)
Query: 37 IQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMK 96
+Q+ TFT+W N HL V R+TDL +DL DG LI LLEVLS + + P+P +M+
Sbjct: 55 VQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEML-----PKPTKGKMR 109
Query: 97 ---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDD 153
LENV AL+FL+ + + L ++ S IVDGN +L+LGLIWT+IL + I + + ++
Sbjct: 110 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEG 169
Query: 154 EDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWD 210
+ R + K LL W Q K P + +TNF W+DG A AL+ P L D++
Sbjct: 170 RETR--SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLI-DFDKLK 226
Query: 211 PNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQF 257
+ N A A+ LG+ ++ PE++ N DE S++TY+ F
Sbjct: 227 DSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAF 273
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 147 bits (371), Expect = 1e-34
Identities = 93/235 (39%), Positives = 136/235 (57%), Gaps = 16/235 (6%)
Query: 26 KDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRK 85
K LA++ + +Q+ TFT+W N HL V R+TDL DL DG LI LLEVLS +R+
Sbjct: 46 KALADER--EAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL--- 100
Query: 86 FHPRPNFRQMK---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYS 142
P+P +M+ LENV AL+FL+ + + L ++ S IVDGN +L LGLIWT+IL +
Sbjct: 101 --PKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQ 158
Query: 143 ISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCA 199
I E ED+++ K++ K LL W Q K P + I NF W+DG A AL+
Sbjct: 159 IQDISVETEDNKE--KKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHR 216
Query: 200 PGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYL 254
P L D++ + N + A A+ LG+ +++ PE+I + DE S++TY+
Sbjct: 217 PDLI-DFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYV 270
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 147 bits (370), Expect = 2e-34
Identities = 90/224 (40%), Positives = 130/224 (58%), Gaps = 14/224 (6%)
Query: 37 IQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMK 96
+Q+ TFT+W N HL V R+TDL DL DG LI LLEVLS +R+ P+P +M+
Sbjct: 42 VQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERL-----PKPTKGRMR 96
Query: 97 ---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDD 153
LENV AL+FL+ + + L ++ S IVDGN +L LGLIWT+IL + I E ED+
Sbjct: 97 IHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDN 156
Query: 154 EDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWD 210
++ K++ K LL W Q K P + I NF W+DG A AL+ P L D++
Sbjct: 157 KE--KKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLI-DFDKLK 213
Query: 211 PNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYL 254
+ N + A A+ LG+ +++ PE+I + DE S++TY+
Sbjct: 214 KSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYV 257
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 145 bits (365), Expect = 7e-34
Identities = 92/231 (39%), Positives = 132/231 (57%), Gaps = 16/231 (6%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL V K + DL DL DG LI+LLEVLS ++ R+ + R
Sbjct: 78 RVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPRE---KGRMRFH 134
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
+L+NV +AL+FL++ +KLV+I + I DGN KL LGLIWT+ILH+ IS E +
Sbjct: 135 RLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGD- 193
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ K++LL W Q + TNF+ W DGK AL+ P L D E
Sbjct: 194 ---MSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLV-DMERVQIQ 249
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQ----FPK 259
EN +A + A+ LGV +++ E++ P+ DE SV+TY+S FPK
Sbjct: 250 SNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPK 299
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
[Homo sapiens]
Length = 2564
Score = 143 bits (361), Expect = 2e-33
Identities = 90/238 (37%), Positives = 134/238 (56%), Gaps = 16/238 (6%)
Query: 26 KDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRK 85
K LA++ + +Q+ TFT+W N HL VG + DL DL DG L LLEVLS +++
Sbjct: 53 KALADER--EAVQKKTFTKWVNSHLARVGCHIGDLYVDLRDGFVLTRLLEVLSGEQL--- 107
Query: 86 FHPRPNFRQMK---LENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYS 142
PRP +M+ LENV AL+FL+ + + L ++ S IVDGN +L LGL+WT+IL +
Sbjct: 108 --PRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTIILRFQ 165
Query: 143 ISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCA 199
I + E ED+ + R + K LL W Q K P++ I NF W+DG A AL+
Sbjct: 166 IQVIKIETEDNRETR--SAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHR 223
Query: 200 PGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQF 257
P L D+ + N + A + A+ LG+ +++ PE++ DE S++TY+ F
Sbjct: 224 PDLV-DFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSF 280
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 142 bits (359), Expect = 3e-33
Identities = 92/251 (36%), Positives = 137/251 (54%), Gaps = 20/251 (7%)
Query: 17 ETDEMPST-EKDLAEDAPWK--------KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDG 67
ET +P+T ++ LA P ++Q+ TFT+W N+HL + ++DL DL DG
Sbjct: 151 ETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDG 210
Query: 68 LRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNL 127
LI+LLEVLS + R+ + R KL+NV +AL++L +KLV+I + I DGN
Sbjct: 211 HNLISLLEVLSGDSLPRE---KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNP 267
Query: 128 KLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRD 184
KL LGLIWT+ILH+ IS + + + T K++LL W Q V L NF
Sbjct: 268 KLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSS 323
Query: 185 WQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPN 244
W+DG+ A++ P L D +EN +A A+ LGV +++ PE++ P
Sbjct: 324 WRDGRLFNAIIHRHKP-LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQ 382
Query: 245 VDEHSVMTYLS 255
DE S++TY+S
Sbjct: 383 PDEKSIITYVS 393
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 142 bits (358), Expect = 4e-33
Identities = 90/250 (36%), Positives = 136/250 (54%), Gaps = 12/250 (4%)
Query: 10 AGLGLGDETDEMPSTEKDLAEDAPWK-KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGL 68
+G G G + E+ + A + ++Q+ TFT+W N+HL + ++DL DL DG
Sbjct: 42 SGGGAGSNGSVLDPAERAVIRIADERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGH 101
Query: 69 RLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLK 128
LI+LLEVLS + R+ + R KL+NV +AL++L +KLV+I + I DGN K
Sbjct: 102 NLISLLEVLSGDSLPRE---KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPK 158
Query: 129 LILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRDW 185
L LGLIWT+ILH+ IS + + + T K++LL W Q V L NF W
Sbjct: 159 LTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSW 214
Query: 186 QDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNV 245
+DG+ A++ P L D +EN +A A+ LGV +++ PE++ P
Sbjct: 215 RDGRLFNAIIHRHKP-LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 273
Query: 246 DEHSVMTYLS 255
DE S++TY+S
Sbjct: 274 DEKSIITYVS 283
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 42 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 98
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 99 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 154
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 155 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 213
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 214 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 256
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 46 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 102
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 103 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 158
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 159 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 217
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 218 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 260
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 42 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 98
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 99 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 154
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 155 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 213
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 214 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 256
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 10 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 66
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 67 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 122
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 123 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 181
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 182 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 224
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 20 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 76
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 77 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 132
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 133 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 191
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 192 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 234
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 141 bits (356), Expect = 8e-33
Identities = 85/223 (38%), Positives = 126/223 (56%), Gaps = 11/223 (4%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
++Q+ TFT+W N+HL + ++DL DL DG LI+LLEVLS + R+ + R
Sbjct: 28 RVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPRE---KGRMRFH 84
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
KL+NV +AL++L +KLV+I + I DGN KL LGLIWT+ILH+ IS + +
Sbjct: 85 KLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQ 140
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ T K++LL W Q V L NF W+DG+ A++ P L D
Sbjct: 141 SEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKP-LLIDMNKVYRQ 199
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLS 255
+EN +A A+ LGV +++ PE++ P DE S++TY+S
Sbjct: 200 TNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVS 242
>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
sapiens]
Length = 1369
Score = 139 bits (351), Expect = 3e-32
Identities = 91/251 (36%), Positives = 136/251 (54%), Gaps = 20/251 (7%)
Query: 17 ETDEMPST-EKDLAEDAPWK--------KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDG 67
ET +P+T ++ LA P ++Q+ T T+W N+HL + ++DL DL DG
Sbjct: 147 ETPVVPATTQRTLARPGPEPAPATDERDRVQKKTSTKWVNKHLIKAQRHISDLYEDLRDG 206
Query: 68 LRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNL 127
LI+LLEVLS + R+ + R KL+NV +AL++L +KLV+I + I DGN
Sbjct: 207 HNLISLLEVLSGDSLPRE---KGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNP 263
Query: 128 KLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKV---PQLPITNFNRD 184
KL LGLIWT+ILH+ IS + + + T K++LL W Q V L NF
Sbjct: 264 KLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSS 319
Query: 185 WQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPN 244
W+DG+ A++ P L D +EN +A A+ LGV +++ PE++ P
Sbjct: 320 WRDGRLFNAIIHRHKP-LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQ 378
Query: 245 VDEHSVMTYLS 255
DE S++TY+S
Sbjct: 379 PDEKSIITYVS 389
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 139 bits (349), Expect = 5e-32
Identities = 89/231 (38%), Positives = 128/231 (55%), Gaps = 16/231 (6%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
K+Q+ TFT+W N+HL V K + DL DL DG LI+LLEVLS + R+ + R
Sbjct: 64 KVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPRE---KGRMRFH 120
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
+L+NV +AL++L+R +KLV+I + I DGN KL LGLIWT+ILH+ IS E ++
Sbjct: 121 RLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESED- 179
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ K+RLL W Q + NF W+DGK A++ P L D
Sbjct: 180 ---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQ 235
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQ----FPK 259
+ N A A+ +GV +++ PE++ + DE SV+TY+S FPK
Sbjct: 236 SNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 285
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 139 bits (349), Expect = 5e-32
Identities = 89/231 (38%), Positives = 128/231 (55%), Gaps = 16/231 (6%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
K+Q+ TFT+W N+HL V K + DL DL DG LI+LLEVLS + R+ + R
Sbjct: 75 KVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPRE---KGRMRFH 131
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
+L+NV +AL++L+R +KLV+I + I DGN KL LGLIWT+ILH+ IS E ++
Sbjct: 132 RLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESED- 190
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ K+RLL W Q + NF W+DGK A++ P L D
Sbjct: 191 ---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQ 246
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQ----FPK 259
+ N A A+ +GV +++ PE++ + DE SV+TY+S FPK
Sbjct: 247 SNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 296
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 139 bits (349), Expect = 5e-32
Identities = 89/231 (38%), Positives = 128/231 (55%), Gaps = 16/231 (6%)
Query: 36 KIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQM 95
K+Q+ TFT+W N+HL V K + DL DL DG LI+LLEVLS + R+ + R
Sbjct: 213 KVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPRE---KGRMRFH 269
Query: 96 KLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDED 155
+L+NV +AL++L+R +KLV+I + I DGN KL LGLIWT+ILH+ IS E ++
Sbjct: 270 RLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESED- 328
Query: 156 ARKQTPKQRLLGWIQNKV---PQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPN 212
+ K+RLL W Q + NF W+DGK A++ P L D
Sbjct: 329 ---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLI-DMNTVAVQ 384
Query: 213 QPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQ----FPK 259
+ N A A+ +GV +++ PE++ + DE SV+TY+S FPK
Sbjct: 385 SNLANLEHAFYVAEK-IGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPK 434
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 121,538,163
Number of Sequences: 37866
Number of extensions: 6666387
Number of successful extensions: 16119
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 11959
Number of HSP's gapped (non-prelim): 631
length of query: 2725
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2605
effective length of database: 13,703,598
effective search space: 35697872790
effective search space used: 35697872790
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.