BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] (423 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] 838 0.0 gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] 826 0.0 gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 788 0.0 gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 461 e-130 gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 459 e-129 gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 95 1e-19 gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 95 1e-19 gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 92 7e-19 gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 84 3e-16 gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s... 84 3e-16 gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa... 83 4e-16 gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 82 7e-16 gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s... 82 1e-15 gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 80 3e-15 gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 79 8e-15 gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 79 8e-15 gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 79 8e-15 gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 77 2e-14 gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 77 2e-14 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 77 3e-14 gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 77 3e-14 gi|20373175 musashi 2 isoform a [Homo sapiens] 77 4e-14 gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 76 7e-14 gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 75 9e-14 gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo... 75 1e-13 gi|25121993 musashi 2 isoform b [Homo sapiens] 75 1e-13 gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor... 74 2e-13 gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 74 2e-13 gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ... 74 2e-13 gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ... 74 2e-13 >gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] Length = 423 Score = 838 bits (2166), Expect = 0.0 Identities = 423/423 (100%), Positives = 423/423 (100%) Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN 60 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN 60 Query: 61 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYR 120 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYR Sbjct: 61 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYR 120 Query: 121 YGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR 180 YGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR Sbjct: 121 YGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR 180 Query: 181 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ 240 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ Sbjct: 181 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ 240 Query: 241 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC 300 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC Sbjct: 241 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC 300 Query: 301 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG 360 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG Sbjct: 301 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG 360 Query: 361 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP 420 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP Sbjct: 361 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP 420 Query: 421 QTM 423 QTM Sbjct: 421 QTM 423 >gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] Length = 439 Score = 826 bits (2134), Expect = 0.0 Identities = 422/439 (96%), Positives = 423/439 (96%), Gaps = 16/439 (3%) Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS- 59 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60 Query: 60 ---------------NRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 104 +RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR Sbjct: 61 KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120 Query: 105 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 164 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR Sbjct: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180 Query: 165 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 224 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA Sbjct: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240 Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT Sbjct: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300 Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 344 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL Sbjct: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360 Query: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 404 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA Sbjct: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420 Query: 405 LNLASQCFQLSSLFTPQTM 423 LNLASQCFQLSSLFTPQTM Sbjct: 421 LNLASQCFQLSSLFTPQTM 439 >gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] Length = 405 Score = 788 bits (2035), Expect = 0.0 Identities = 405/423 (95%), Positives = 405/423 (95%), Gaps = 18/423 (4%) Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN 60 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN 60 Query: 61 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYR 120 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATG Sbjct: 61 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATG-- 118 Query: 121 YGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR 180 EPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR Sbjct: 119 ----------------EPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR 162 Query: 181 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ 240 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ Sbjct: 163 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ 222 Query: 241 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC 300 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC Sbjct: 223 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC 282 Query: 301 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG 360 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG Sbjct: 283 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG 342 Query: 361 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP 420 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP Sbjct: 343 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP 402 Query: 421 QTM 423 QTM Sbjct: 403 QTM 405 >gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] Length = 524 Score = 461 bits (1186), Expect = e-130 Identities = 266/449 (59%), Positives = 314/449 (69%), Gaps = 55/449 (12%) Query: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66 DI IEAMLEAPYKK+E++ ++ S S S + S ++ R R RD Sbjct: 4 DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRS---KSKERKRSRD 60 Query: 67 RYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSP------------- 113 R R++ S+SR R RSRS +RR S SRSRD R R YRSP Sbjct: 61 RERKK-SKSRE-----RKRSRSKERRR-SRSRSRDRRFRGR--YRSPYSGPKFNSAIRGK 111 Query: 114 -----PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLED 168 + R SKSP ++KSPVREP+DNL+PEERDARTVFCMQLAARIRPRDLE+ Sbjct: 112 IGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEE 171 Query: 169 FFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAE 228 FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAE Sbjct: 172 FFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAE 231 Query: 229 KNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288 KNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSK Sbjct: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291 Query: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDL 344 GYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + +F D D+ +DL Sbjct: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDL 351 Query: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL----------- 393 G+ GR QLMA+LAEG G+Q+P A ALQ++G++ GA+ Sbjct: 352 GTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVADLQTRLSQQT 401 Query: 394 NPAALTALSPALNLASQCFQLSSLFTPQT 422 +AL A + LA+QCFQLS++F PQT Sbjct: 402 EASALAAAASVQPLATQCFQLSNMFNPQT 430 >gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] Length = 530 Score = 459 bits (1180), Expect = e-129 Identities = 266/455 (58%), Positives = 314/455 (69%), Gaps = 61/455 (13%) Query: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66 DI IEAMLEAPYKK+E++ ++ S S S + S ++ R R RD Sbjct: 4 DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRS---KSKERKRSRD 60 Query: 67 RYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSP------------- 113 R R++ S+SR R RSRS +RR S SRSRD R R YRSP Sbjct: 61 RERKK-SKSRE-----RKRSRSKERRR-SRSRSRDRRFRGR--YRSPYSGPKFNSAIRGK 111 Query: 114 -----PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLED 168 + R SKSP ++KSPVREP+DNL+PEERDARTVFCMQLAARIRPRDLE+ Sbjct: 112 IGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEE 171 Query: 169 FFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAE 228 FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAE Sbjct: 172 FFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAE 231 Query: 229 KNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288 KNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSK Sbjct: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291 Query: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDL 344 GYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + +F D D+ +DL Sbjct: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDL 351 Query: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL----------- 393 G+ GR QLMA+LAEG G+Q+P A ALQ++G++ GA+ Sbjct: 352 GTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVAEFSFVIDLQT 401 Query: 394 ------NPAALTALSPALNLASQCFQLSSLFTPQT 422 +AL A + LA+QCFQLS++F PQT Sbjct: 402 RLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 436 >gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo sapiens] Length = 516 Score = 94.7 bits (234), Expect = 1e-19 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%) Query: 138 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 193 P+ +++ + + A + C I ED F+ G ++ + + D + + KG Sbjct: 70 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 129 Query: 194 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 253 A+VE+ ++ LA+ +LG I + + + + L + R+YV S Sbjct: 130 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 189 Query: 254 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 313 +H ++++D ++ +FE FGKI + L +D TG+ KGYGFI + ++ ++ A+ +N F+L Sbjct: 190 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 249 Query: 314 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 373 G+ +RVG +T P M L LP AA AA Sbjct: 250 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 283 Query: 374 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 408 AAA Q + GA LG L L +SPAL LA Sbjct: 284 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 318 >gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo sapiens] Length = 559 Score = 94.7 bits (234), Expect = 1e-19 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%) Query: 138 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 193 P+ +++ + + A + C I ED F+ G ++ + + D + + KG Sbjct: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172 Query: 194 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 253 A+VE+ ++ LA+ +LG I + + + + L + R+YV S Sbjct: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232 Query: 254 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 313 +H ++++D ++ +FE FGKI + L +D TG+ KGYGFI + ++ ++ A+ +N F+L Sbjct: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292 Query: 314 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 373 G+ +RVG +T P M L LP AA AA Sbjct: 293 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 326 Query: 374 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 408 AAA Q + GA LG L L +SPAL LA Sbjct: 327 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 361 >gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo sapiens] Length = 542 Score = 92.4 bits (228), Expect = 7e-19 Identities = 70/241 (29%), Positives = 113/241 (46%), Gaps = 30/241 (12%) Query: 170 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 229 F+ G ++ + + D + + KG A+VE+ ++ LA+ +LG I + Sbjct: 132 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 191 Query: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289 + + + L + R+YV S+H ++++D ++ +FE FGKI + L +D TG+ KG Sbjct: 192 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 251 Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGG 349 YGFI + ++ ++ A+ +N F+L G+ +RVG +T P Sbjct: 252 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA---------VTPP------------- 289 Query: 350 RFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQ--LNGAVPLGALNPAALTALSPALNL 407 M L LP AA AAAAA Q + GA LG L L +SPAL L Sbjct: 290 ----MPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTL 343 Query: 408 A 408 A Sbjct: 344 A 344 Score = 68.2 bits (165), Expect = 1e-11 Identities = 37/98 (37%), Positives = 56/98 (57%) Query: 224 ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSD 283 A Q ++ MA Q+ R+YVGS+++ + ED +R F PFG I +I + DS Sbjct: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148 Query: 284 TGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVG 321 T + KG+ F+ + E A+ ALEQ+N L GR ++VG Sbjct: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186 Score = 35.0 bits (79), Expect = 0.13 Identities = 15/65 (23%), Positives = 32/65 (49%) Query: 139 VDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 198 +D L+ E R ++ + + D++ F A GK++ + D + + KG ++E+ Sbjct: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257 Query: 199 CEIQS 203 + QS Sbjct: 258 EKAQS 262 >gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo sapiens] Length = 448 Score = 83.6 bits (205), Expect = 3e-16 Identities = 86/332 (25%), Positives = 139/332 (41%), Gaps = 83/332 (25%) Query: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171 S P + G+ G S SP P+++ DA +F Q+ + +DL+ F Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75 Query: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNR 231 GK+ ++ ++ DR + KG A++ +CE +S A Q++ E+ Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKA---------------QSALHEQKT 120 Query: 232 LAAMANNLQ------KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTG 285 L M +Q + G +L+VG L+ +ED +R +FE FG I+ +++ D G Sbjct: 121 LPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-G 179 Query: 286 RSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE- 341 SKG F+ +S A+ A+ L+G ++ + G + + F D D+E Sbjct: 180 NSKGCAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKER 226 Query: 342 -------------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAA 374 + G+ G Q LMA +A+G L AA AAA Sbjct: 227 TMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAA 284 Query: 375 AAAQAAALQLNG--AVPL----GALNPAALTA 400 Q AAL +NG A P+ G P +TA Sbjct: 285 QMQQMAALNMNGLAAAPMTPTSGGSTPPGITA 316 >gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo sapiens] Length = 485 Score = 83.6 bits (205), Expect = 3e-16 Identities = 85/327 (25%), Positives = 142/327 (43%), Gaps = 64/327 (19%) Query: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171 S P + G+ G S SP P+++ DA +F Q+ + +DL+ F Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75 Query: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 229 GK+ ++ ++ DR + KG A++ +CE +S A ++ L G+ +Q A+ Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135 Query: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289 ++ L++ +L+VG L+ +ED +R +FE FG I+ +++ D G SKG Sbjct: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193 Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 341 F+ +S A+ A+ L+G ++ + G + + F D D+E Sbjct: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240 Query: 342 ---------------LDLGSAGGRFQ-------LMAKLAEGAGIQLPSTAAAAAAAAAQA 379 + G+ G Q LMA +A+G L AA AAA Q Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGG--YLNPMAAFAAAQMQQM 298 Query: 380 AALQLNG--AVPL----GALNPAALTA 400 AAL +NG A P+ G P +TA Sbjct: 299 AALNMNGLAAAPMTPTSGGSTPPGITA 325 Score = 28.9 bits (63), Expect = 9.2 Identities = 9/31 (29%), Positives = 22/31 (70%) Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRV 320 +GF++F + A+ A++ +NGF++ + ++V Sbjct: 443 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 473 >gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sapiens] Length = 486 Score = 83.2 bits (204), Expect = 4e-16 Identities = 85/328 (25%), Positives = 142/328 (43%), Gaps = 65/328 (19%) Query: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171 S P + G+ G S SP P+++ DA +F Q+ + +DL+ F Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75 Query: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 229 GK+ ++ ++ DR + KG A++ +CE +S A ++ L G+ +Q A+ Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135 Query: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289 ++ L++ +L+VG L+ +ED +R +FE FG I+ +++ D G SKG Sbjct: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193 Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 341 F+ +S A+ A+ L+G ++ + G + + F D D+E Sbjct: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240 Query: 342 ---------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAAAAAQ 378 + G+ G Q LMA +A+G L AA AAA Q Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAAQMQQ 298 Query: 379 AAALQLNG--AVPL----GALNPAALTA 400 AAL +NG A P+ G P +TA Sbjct: 299 MAALNMNGLAAAPMTPTSGGSTPPGITA 326 Score = 28.9 bits (63), Expect = 9.2 Identities = 9/31 (29%), Positives = 22/31 (70%) Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRV 320 +GF++F + A+ A++ +NGF++ + ++V Sbjct: 444 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 474 >gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo sapiens] Length = 370 Score = 82.4 bits (202), Expect = 7e-16 Identities = 51/178 (28%), Positives = 99/178 (55%), Gaps = 8/178 (4%) Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-L 210 VF L I + L + FSA GK+ +++SD + SKG A+V F + AI + Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157 Query: 211 TGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPF 270 G+ L G + V + K+R A + + + +Y+ + ++ ++ L+ +F + Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFTN----VYIKNFGGDMDDERLKDVFSKY 213 Query: 271 GKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328 GK ++ +M DS +G+SKG+GF++F E A++A+E++NG ++ G+ + VG ++++ Sbjct: 214 GKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270 Score = 74.7 bits (182), Expect = 1e-13 Identities = 50/163 (30%), Positives = 88/163 (53%), Gaps = 12/163 (7%) Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224 L+D FS GK V++++D +S +SKG +V F ++ A+ + G+ + G I V Sbjct: 206 LKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR 264 Query: 225 SQAEKNRLAAMANNLQ-------KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIV 277 +Q + R A + + +G G ++LY+ +L I ++ LR F FG I + Sbjct: 265 AQKKVERQAELKQMFEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVK 323 Query: 278 LMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 320 +M++ G+SKG+G I FS E A +A+ ++NG L +P+ + Sbjct: 324 VMQEE--GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364 Score = 65.9 bits (159), Expect = 7e-11 Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 11/159 (6%) Query: 170 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 229 FS VG V +RI D+ +RRS G AYV F ++ A+ ++ + + Sbjct: 30 FSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDII---------KGKS 80 Query: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289 RL + G +++ +L +I L F FGKI + +M D D G SKG Sbjct: 81 IRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD-DQG-SKG 138 Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328 Y F+ F + A RA+E++NG L G + VG R D Sbjct: 139 YAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKD 177 Score = 51.6 bits (122), Expect = 1e-06 Identities = 26/72 (36%), Positives = 43/72 (59%) Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LYVG LH ++TED+L F G + +I + +D T RS GY ++ F A++AL+ + Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71 Query: 309 NGFELAGRPMRV 320 N + G+ +R+ Sbjct: 72 NFDIIKGKSIRL 83 >gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo sapiens] Length = 484 Score = 81.6 bits (200), Expect = 1e-15 Identities = 87/329 (26%), Positives = 142/329 (43%), Gaps = 69/329 (20%) Query: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171 S P + G+ G S SP P+++ DA +F Q+ + +DL+ F Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75 Query: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLA-IGLTGQRLL---GVPIIVQASQA 227 GK+ ++ ++ DR + KG A++ +CE +S A L Q+ L PI V+ + + Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135 Query: 228 EKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRS 287 E ++ + +L+VG L+ +ED +R +FE FG I+ +++ D G S Sbjct: 136 ESRG----GSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNS 190 Query: 288 KGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE--- 341 KG F+ +S A+ A+ L+G ++ + G + + F D D+E Sbjct: 191 KGCAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTM 237 Query: 342 -----------------LDLGSAGGRFQ-------LMAKLAEGAGIQLPSTAAAAAAAAA 377 + G+ G Q LMA +A+G L AA AAA Sbjct: 238 RRMQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGG--YLNPMAAFAAAQMQ 295 Query: 378 QAAALQLNG--AVPL----GALNPAALTA 400 Q AAL +NG A P+ G P +TA Sbjct: 296 QMAALNMNGLAAAPMTPTSGGSTPPGITA 324 Score = 28.9 bits (63), Expect = 9.2 Identities = 9/31 (29%), Positives = 22/31 (70%) Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRV 320 +GF++F + A+ A++ +NGF++ + ++V Sbjct: 442 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 472 >gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] Length = 288 Score = 80.5 bits (197), Expect = 3e-15 Identities = 61/170 (35%), Positives = 83/170 (48%), Gaps = 11/170 (6%) Query: 31 KKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRDRYRRRNSRSRSPGRQCRHRSRSWD 90 +++Y + S S SG+ + T RSR ++ RR S+SRS + R RSR Sbjct: 6 EQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRS-ESRSRSRRSS 64 Query: 91 RRH--GSESRSRDHRREDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERD 148 RRH S SRSR HRR RS + YR HS S H + R + +P+ Sbjct: 65 RRHYTRSRSRSRSHRRS-----RSRSYSRDYRRRHSHS-HSPMSTRRRHVGNRANPDPNC 118 Query: 149 ARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 198 VF + L RDL + FS G + DV I+ D+ SRRS+G A+V F Sbjct: 119 CLGVFGLSLYTT--ERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYF 166 Score = 51.6 bits (122), Expect = 1e-06 Identities = 27/72 (37%), Positives = 42/72 (58%) Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 L V L TE LR +F +G I ++ ++ D + RS+G+ F+ F + + A+ A E+ Sbjct: 120 LGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERA 179 Query: 309 NGFELAGRPMRV 320 NG EL GR +RV Sbjct: 180 NGMELDGRRIRV 191 >gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo sapiens] Length = 631 Score = 79.0 bits (193), Expect = 8e-15 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%) Query: 118 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 163 GY Y + + P E++ P+R P R + VF L I Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112 Query: 164 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 222 + L D FSA G + +++ D N SKG A+V F ++ AI + G L + V Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170 Query: 223 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 282 ++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226 Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328 + G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++ Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 76.3 bits (186), Expect = 5e-14 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%) Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195 +E L + ++ V+ + L++ FS GK V+++ D N + SKG + Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235 Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 248 V + + + A+ + G+ + G I V +Q + R A + ++ + Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295 Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 309 NGFELAGRPMRV 320 NG + +P+ V Sbjct: 354 NGRIVGSKPLYV 365 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%) Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224 L + FS G V +R+ D +RRS G AYV F + A+ + + G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284 SQ + +L+K G +++ +L +I L F FG I + ++ D Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134 Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326 SKGY F+ F E A +A+E++NG L R + VG R Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176 Score = 58.2 bits (139), Expect = 1e-08 Identities = 29/72 (40%), Positives = 43/72 (59%) Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ + Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 309 NGFELAGRPMRV 320 N + G+P+R+ Sbjct: 73 NFDVIKGKPIRI 84 >gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo sapiens] Length = 644 Score = 79.0 bits (193), Expect = 8e-15 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%) Query: 118 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 163 GY Y + + P E++ P+R P R + VF L I Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112 Query: 164 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 222 + L D FSA G + +++ D N SKG A+V F ++ AI + G L + V Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170 Query: 223 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 282 ++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226 Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328 + G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++ Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 76.3 bits (186), Expect = 5e-14 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%) Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195 +E L + ++ V+ + L++ FS GK V+++ D N + SKG + Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235 Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 248 V + + + A+ + G+ + G I V +Q + R A + ++ + Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295 Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 309 NGFELAGRPMRV 320 NG + +P+ V Sbjct: 354 NGRIVGSKPLYV 365 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%) Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224 L + FS G V +R+ D +RRS G AYV F + A+ + + G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284 SQ + +L+K G +++ +L +I L F FG I + ++ D Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134 Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326 SKGY F+ F E A +A+E++NG L R + VG R Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176 Score = 58.2 bits (139), Expect = 1e-08 Identities = 29/72 (40%), Positives = 43/72 (59%) Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ + Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 309 NGFELAGRPMRV 320 N + G+P+R+ Sbjct: 73 NFDVIKGKPIRI 84 >gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo sapiens] Length = 660 Score = 79.0 bits (193), Expect = 8e-15 Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%) Query: 118 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 163 GY Y + + P E++ P+R P R + VF L I Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112 Query: 164 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 222 + L D FSA G + +++ D N SKG A+V F ++ AI + G L + V Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170 Query: 223 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 282 ++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226 Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328 + G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++ Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271 Score = 76.3 bits (186), Expect = 5e-14 Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%) Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195 +E L + ++ V+ + L++ FS GK V+++ D N + SKG + Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235 Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 248 V + + + A+ + G+ + G I V +Q + R A + ++ + Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295 Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 309 NGFELAGRPMRV 320 NG + +P+ V Sbjct: 354 NGRIVGSKPLYV 365 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%) Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224 L + FS G V +R+ D +RRS G AYV F + A+ + + G PI + Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86 Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284 SQ + +L+K G +++ +L +I L F FG I + ++ D Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134 Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326 SKGY F+ F E A +A+E++NG L R + VG R Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176 Score = 58.2 bits (139), Expect = 1e-08 Identities = 29/72 (40%), Positives = 43/72 (59%) Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ + Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 309 NGFELAGRPMRV 320 N + G+P+R+ Sbjct: 73 NFDVIKGKPIRI 84 >gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] Length = 375 Score = 77.4 bits (189), Expect = 2e-14 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 11/183 (6%) Query: 145 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 204 ++ RT++ L+ + + FS +G + ++I++ S + +VEF E + Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDA 61 Query: 205 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 263 A+ + G+++LG + K A ++ +K ++VG L IT + + Sbjct: 62 AAALAAMNGRKILGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 113 Query: 264 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 323 + F PFGKI + ++KD TG+SKGYGF++F + A A+ + G L GR +R Sbjct: 114 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 173 Query: 324 TER 326 T + Sbjct: 174 TRK 176 Score = 68.2 bits (165), Expect = 1e-11 Identities = 48/182 (26%), Positives = 78/182 (42%), Gaps = 23/182 (12%) Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 211 VF L+ I D++ F+ GK+ D R++ D + +SKG +V F AI Sbjct: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158 Query: 212 GQRLLG--------------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFN 257 G + LG P Q + ++ R + N N +Y G + Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKN---CTVYCGGIASG 215 Query: 258 ITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRP 317 +T+ ++R F PFG+I I + + KGY F+ FS E A A+ +NG + G Sbjct: 216 LTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHV 269 Query: 318 MR 319 ++ Sbjct: 270 VK 271 Score = 40.4 bits (93), Expect = 0.003 Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 2/86 (2%) Query: 239 LQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDS 298 + + +G P LYVG+L ++TE ++ +F G + ++ + + + Y F+ F + Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEH 58 Query: 299 ECARRALEQLNGFELAGRPMRVGHVT 324 A AL +NG ++ G+ ++V T Sbjct: 59 RDAAAALAAMNGRKILGKEVKVNWAT 84 Score = 29.6 bits (65), Expect = 5.4 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 15/98 (15%) Query: 111 RSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFF 170 R PP + ++K F + V+ SP+ TV+C +A+ + + + F Sbjct: 175 RKPPAPKSTQENNTKQLRFEDV------VNQSSPKNC---TVYCGGIASGLTDQLMRQTF 225 Query: 171 SAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAI 208 S G++ ++R+ + KG ++V F +S AI Sbjct: 226 SPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAI 257 >gi|188219593 TIA1 protein isoform 1 [Homo sapiens] Length = 375 Score = 77.4 bits (189), Expect = 2e-14 Identities = 48/183 (26%), Positives = 92/183 (50%), Gaps = 11/183 (6%) Query: 145 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 204 E+ +T++ L+ + + FS +G ++ ++I D + + +VEF E + Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59 Query: 205 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 263 A+ + G++++G + K A ++ +K ++VG L IT + + Sbjct: 60 AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111 Query: 264 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 323 + F PFG+I + ++KD TG+SKGYGF++F + A A++Q+ G L GR +R Sbjct: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171 Query: 324 TER 326 T + Sbjct: 172 TRK 174 Score = 67.8 bits (164), Expect = 2e-11 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%) Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 211 VF L+ I D++ F+ G++ D R++ D + +SKG +V F AI Sbjct: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156 Query: 212 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260 G + LG P +++ + + + + + +Y G + +TE Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216 Query: 261 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 320 ++R F PFG+I I + D KGY F+ F+ E A A+ +NG + G ++ Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 270 Query: 321 GHVTERLD 328 E LD Sbjct: 271 YWGKETLD 278 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 77.0 bits (188), Expect = 3e-14 Identities = 56/187 (29%), Positives = 88/187 (47%), Gaps = 14/187 (7%) Query: 142 LSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEI 201 +S +DA TV+ L ++ L + F G V + + DR + + +G +VEF Sbjct: 6 ISERNQDA-TVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64 Query: 202 QSVPLAIGLTGQ-RLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260 + AI + +L G PI V + A L AN +++G+L I E Sbjct: 65 EDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGAN-----------IFIGNLDPEIDE 113 Query: 261 DMLRGIFEPFGKI-DNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 319 +L F FG I +M+D DTG SKGY FI F+ + + A+E +NG L RP+ Sbjct: 114 KLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPIT 173 Query: 320 VGHVTER 326 V + ++ Sbjct: 174 VSYAFKK 180 Score = 58.9 bits (141), Expect = 8e-09 Identities = 34/98 (34%), Positives = 55/98 (56%), Gaps = 3/98 (3%) Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 +YVG L ++E +L +F G + N + KD TG+ +GYGF+ F E A A++ + Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74 Query: 309 NGFELAGRPMRVGHVT---ERLDGGTDITFPDGDQELD 343 N +L G+P+RV + + LD G +I + D E+D Sbjct: 75 NMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEID 112 >gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] Length = 636 Score = 77.0 bits (188), Expect = 3e-14 Identities = 59/231 (25%), Positives = 112/231 (48%), Gaps = 22/231 (9%) Query: 118 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 163 GY Y + + P E++ PVR P R + +F L I Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDN 112 Query: 164 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 222 + L D FSA G + +++ D N SKG +V F ++ AI + G L + V Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170 Query: 223 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 282 ++ K R A + ++ +Y+ + ++ ++ L+ +F FG ++ +M D Sbjct: 171 GRFKSRKEREAELGARAKEFTN----VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD- 225 Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDI 333 ++G+SKG+GF++F E A++A++++NG EL G+ + VG ++++ T++ Sbjct: 226 ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL 276 Score = 72.8 bits (177), Expect = 6e-13 Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 10/192 (5%) Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195 +E L ++ V+ + L+D F G V++++D S +SKG + Sbjct: 177 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 235 Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM------R 248 V F + A+ + G+ L G I V +Q + R + ++ + Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVN 295 Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LYV +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 309 NGFELAGRPMRV 320 NG +A +P+ V Sbjct: 354 NGRIVATKPLYV 365 Score = 65.1 bits (157), Expect = 1e-10 Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 13/162 (8%) Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224 L + FS G + +R+ D +RRS G AYV F + A+ + + G P+ + Sbjct: 27 LYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMW 86 Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284 SQ + +L+K G +++ +L +I L F FG I + ++ D Sbjct: 87 SQRDP--------SLRKSGVG--NIFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134 Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326 SKGYGF+ F E A RA+E++NG L R + VG R Sbjct: 135 NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSR 176 Score = 57.8 bits (138), Expect = 2e-08 Identities = 30/72 (41%), Positives = 43/72 (59%) Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LYVG LH ++TE ML F P G I +I + +D T RS GY ++ F A RAL+ + Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 309 NGFELAGRPMRV 320 N + G+P+R+ Sbjct: 73 NFDVIKGKPVRI 84 >gi|20373175 musashi 2 isoform a [Homo sapiens] Length = 328 Score = 76.6 bits (187), Expect = 4e-14 Identities = 64/263 (24%), Positives = 114/263 (43%), Gaps = 23/263 (8%) Query: 146 ERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVP 205 + D +F L+ + P L D+FS G++R+ ++ D ++RS+G +V F + SV Sbjct: 17 QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV- 75 Query: 206 LAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRG 265 ++LG P S+ ++A K +++VG L N + ++ Sbjct: 76 -------DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQ 128 Query: 266 IFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTE 325 FE FGK+++ +LM D T R +G+GF+TF + + + E ++ E+ + + Sbjct: 129 YFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE-IHFHEINNKMVECKKAQP 187 Query: 326 RLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGI----QLPSTAAAAAAAAAQAAA 381 + ++ FP G + G A G M G G+ +T A + Sbjct: 188 K-----EVMFPPGTR----GRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYG 238 Query: 382 LQLNGAVPLGALNPAALTALSPA 404 Q G P A P A A++ A Sbjct: 239 YQFPG-FPAAAYGPVAAAAVAAA 260 Score = 53.9 bits (128), Expect = 3e-07 Identities = 25/80 (31%), Positives = 42/80 (52%) Query: 228 EKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRS 287 E N + + P ++++G L + + D LR F FG+I ++M+D T RS Sbjct: 2 EANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRS 61 Query: 288 KGYGFITFSDSECARRALEQ 307 +G+GF+TF+D + L Q Sbjct: 62 RGFGFVTFADPASVDKVLGQ 81 >gi|188219591 TIA1 protein isoform 2 [Homo sapiens] Length = 386 Score = 75.9 bits (185), Expect = 7e-14 Identities = 49/187 (26%), Positives = 96/187 (51%), Gaps = 8/187 (4%) Query: 145 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 204 E+ +T++ L+ + + FS +G ++ ++I D + + +VEF E + Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59 Query: 205 PLAIG-LTGQRLLGVPIIVQ----ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNIT 259 A+ + G++++G + V S +K+ ++ + Q+ ++VG L IT Sbjct: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDH-FHVFVGDLSPEIT 118 Query: 260 EDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 319 + ++ F PFG+I + ++KD TG+SKGYGF++F + A A++Q+ G L GR +R Sbjct: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178 Query: 320 VGHVTER 326 T + Sbjct: 179 TNWATRK 185 Score = 67.8 bits (164), Expect = 2e-11 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%) Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 211 VF L+ I D++ F+ G++ D R++ D + +SKG +V F AI Sbjct: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167 Query: 212 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260 G + LG P +++ + + + + + +Y G + +TE Sbjct: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227 Query: 261 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 320 ++R F PFG+I I + D KGY F+ F+ E A A+ +NG + G ++ Sbjct: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 281 Query: 321 GHVTERLD 328 E LD Sbjct: 282 YWGKETLD 289 >gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] Length = 631 Score = 75.5 bits (184), Expect = 9e-14 Identities = 49/183 (26%), Positives = 96/183 (52%), Gaps = 8/183 (4%) Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-L 210 +F L I + L D SA G + ++ D N SKG +V F ++ AI + Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG--SKGYGFVHFETHEAAERAIKKM 158 Query: 211 TGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPF 270 G L G + V ++ K R A + ++ +Y+ + ++ ++ L+ +F F Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFPN----VYIKNFGEDMDDERLKDLFGKF 214 Query: 271 GKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGG 330 G ++ +M D ++G+SKG+GF++F E A++A++++NG EL G+ + VG ++++ Sbjct: 215 GPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273 Query: 331 TDI 333 T++ Sbjct: 274 TEL 276 Score = 73.2 bits (178), Expect = 4e-13 Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 10/192 (5%) Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195 +E L ++ V+ + L+D F G V++++D S +SKG + Sbjct: 177 KEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 235 Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM------R 248 V F + A+ + G+ L G I V +Q + R + ++ + Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVN 295 Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LYV +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++ Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 309 NGFELAGRPMRV 320 NG +A +P+ V Sbjct: 354 NGRIVATKPLYV 365 Score = 57.4 bits (137), Expect = 2e-08 Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 17/164 (10%) Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224 L + FS G + +RI D + S AYV F + A+ + + G P+ + Sbjct: 27 LYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMW 86 Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKI--DNIVLMKDS 282 SQ + +L+K G ++V +L +I L FG I N+V Sbjct: 87 SQRDP--------SLRKSGVG--NIFVKNLDKSINNKALYDTVSAFGNILSCNVV----C 132 Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326 D SKGYGF+ F E A RA++++NG L GR + VG R Sbjct: 133 DENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSR 176 Score = 53.5 bits (127), Expect = 3e-07 Identities = 27/72 (37%), Positives = 42/72 (58%) Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308 LYVG LH ++TE ML F P G I +I + +D T S Y ++ F ++ A AL+ + Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72 Query: 309 NGFELAGRPMRV 320 N + G+P+R+ Sbjct: 73 NFDVIKGKPVRI 84 >gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo sapiens] Length = 420 Score = 74.7 bits (182), Expect = 1e-13 Identities = 69/260 (26%), Positives = 113/260 (43%), Gaps = 32/260 (12%) Query: 62 SRDRDRYRRRNSRSRSPGRQC--------RHRSRSWDRRHGSES---RSRDHRREDRVHY 110 +R R +R+ ++ P R R R RRH S RS R Sbjct: 50 ARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTAR 109 Query: 111 RSPPLATGYRYG----HSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDL 166 + PP + +S F E S + N S ++D +F L+ +DL Sbjct: 110 QHPPADSSVTMEDMNEYSNIEEFAEGSKI-----NASKNQQDDGKMFIGGLSWDTSKKDL 164 Query: 167 EDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQ 226 ++ S G+V D I +D + RS+G +V F + SV + L +L G I + ++ Sbjct: 165 TEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAK 224 Query: 227 AEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGR 286 A KG P +++VG L + +E+ ++ F FG+I+NI L D+ T Sbjct: 225 A------------LKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNE 272 Query: 287 SKGYGFITFSDSECARRALE 306 +G+ FIT++D E ++ LE Sbjct: 273 RRGFCFITYTDEEPVKKLLE 292 >gi|25121993 musashi 2 isoform b [Homo sapiens] Length = 251 Score = 74.7 bits (182), Expect = 1e-13 Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 8/155 (5%) Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 211 +F L+ + P L D+FS G++R+ ++ D ++RS+G +V F + SV Sbjct: 19 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV------- 71 Query: 212 GQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFG 271 ++LG P S+ ++A K +++VG L N + ++ FE FG Sbjct: 72 -DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFG 130 Query: 272 KIDNIVLMKDSDTGRSKGYGFITFSDSECARRALE 306 K+++ +LM D T R +G+GF+TF + + + E Sbjct: 131 KVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 165 Score = 52.0 bits (123), Expect = 1e-06 Identities = 22/60 (36%), Positives = 37/60 (61%) Query: 248 RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 307 ++++G L + + D LR F FG+I ++M+D T RS+G+GF+TF+D + L Q Sbjct: 18 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77 >gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a [Homo sapiens] Length = 475 Score = 74.3 bits (181), Expect = 2e-13 Identities = 83/348 (23%), Positives = 135/348 (38%), Gaps = 83/348 (23%) Query: 59 SNRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSE-SRSRDHRREDRVHYRSPPLAT 117 + + RD++ R+ S SRS R + RSRS DRR+ + S SRD RR RS PL Sbjct: 14 NKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR------RSKPLTR 67 Query: 118 GYRYGHS---KSPHFREKSPVREPVD------------------------------NLSP 144 G + H +SP +K VR+ D ++P Sbjct: 68 GAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTP 127 Query: 145 E----------------ERDARTVFCMQLAARIRPRDLEDFFSAVGK-----------VR 177 + R AR ++ + I + DFF+A + V Sbjct: 128 DGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVL 187 Query: 178 DVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMAN 237 V+I D+N A++EF + A+ G G + ++ + L M+ Sbjct: 188 AVQINQDKN------FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSE 240 Query: 238 NLQKGNGGPM---------RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288 N G + +L++G L + +D ++ + FG + L+KDS TG SK Sbjct: 241 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK 300 Query: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFP 336 GY F + D +A+ LNG +L + + V + T ++ P Sbjct: 301 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPP 348 >gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform B1 [Homo sapiens] Length = 353 Score = 74.3 bits (181), Expect = 2e-13 Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 8/170 (4%) Query: 131 EKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRS 190 EK+ P++ E+ R +F L+ L +++ GK+ D ++ D S+RS Sbjct: 2 EKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRS 61 Query: 191 KGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMR-L 249 +G +V F + V A+ P + E R A + + G ++ L Sbjct: 62 RGFGFVTFSSMAEVDAAMAAR-------PHSIDGRVVEPKRAVAREESGKPGAHVTVKKL 114 Query: 250 YVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 299 +VG + + E LR FE +GKID I ++ D +G+ +G+GF+TF D + Sbjct: 115 FVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD 164 >gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b [Homo sapiens] Length = 285 Score = 74.3 bits (181), Expect = 2e-13 Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 13/167 (7%) Query: 141 NLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCE 200 N S E DA +F L+ +DL+D+F+ G+V D I D N+ RS+G ++ F + Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120 Query: 201 IQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260 SV + RL G I + + AM + K +++VG L+ TE Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167 Query: 261 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 307 + +R F FG+I+ I L D + +G+ FITF + E ++ LE+ Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214 >gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a [Homo sapiens] Length = 332 Score = 74.3 bits (181), Expect = 2e-13 Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 13/167 (7%) Query: 141 NLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCE 200 N S E DA +F L+ +DL+D+F+ G+V D I D N+ RS+G ++ F + Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120 Query: 201 IQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260 SV + RL G I + + AM + K +++VG L+ TE Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167 Query: 261 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 307 + +R F FG+I+ I L D + +G+ FITF + E ++ LE+ Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,926,694 Number of Sequences: 37866 Number of extensions: 747464 Number of successful extensions: 8443 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 337 Number of HSP's successfully gapped in prelim test: 201 Number of HSP's that attempted gapping in prelim test: 5039 Number of HSP's gapped (non-prelim): 2024 length of query: 423 length of database: 18,247,518 effective HSP length: 105 effective length of query: 318 effective length of database: 14,271,588 effective search space: 4538364984 effective search space used: 4538364984 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.