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Search of human proteins with 116734694
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116734694 RNA binding motif protein 23 isoform 2 [Homo
sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] 838 0.0
gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] 826 0.0
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 788 0.0
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 461 e-130
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 459 e-129
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 95 1e-19
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 95 1e-19
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 92 7e-19
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 84 3e-16
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s... 84 3e-16
gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa... 83 4e-16
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 82 7e-16
gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s... 82 1e-15
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 80 3e-15
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 79 8e-15
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 79 8e-15
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 79 8e-15
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 77 2e-14
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 77 2e-14
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 77 3e-14
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 77 3e-14
gi|20373175 musashi 2 isoform a [Homo sapiens] 77 4e-14
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 76 7e-14
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 75 9e-14
gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo... 75 1e-13
gi|25121993 musashi 2 isoform b [Homo sapiens] 75 1e-13
gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor... 74 2e-13
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 74 2e-13
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ... 74 2e-13
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ... 74 2e-13
>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
Length = 423
Score = 838 bits (2166), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN 60
MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN
Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN 60
Query: 61 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYR 120
RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYR
Sbjct: 61 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYR 120
Query: 121 YGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR 180
YGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR
Sbjct: 121 YGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR 180
Query: 181 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ 240
IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ
Sbjct: 181 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ 240
Query: 241 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC 300
KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC
Sbjct: 241 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC 300
Query: 301 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG 360
ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG
Sbjct: 301 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG 360
Query: 361 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP 420
AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP
Sbjct: 361 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP 420
Query: 421 QTM 423
QTM
Sbjct: 421 QTM 423
>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
Length = 439
Score = 826 bits (2134), Expect = 0.0
Identities = 422/439 (96%), Positives = 423/439 (96%), Gaps = 16/439 (3%)
Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS- 59
MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETS
Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSK 60
Query: 60 ---------------NRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 104
+RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR
Sbjct: 61 KKRSRSHNKSRDRKRSRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRR 120
Query: 105 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 164
EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR
Sbjct: 121 EDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPR 180
Query: 165 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 224
DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA
Sbjct: 181 DLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQA 240
Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284
SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT
Sbjct: 241 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 300
Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 344
GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL
Sbjct: 301 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDL 360
Query: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 404
GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA
Sbjct: 361 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPA 420
Query: 405 LNLASQCFQLSSLFTPQTM 423
LNLASQCFQLSSLFTPQTM
Sbjct: 421 LNLASQCFQLSSLFTPQTM 439
>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
Length = 405
Score = 788 bits (2035), Expect = 0.0
Identities = 405/423 (95%), Positives = 405/423 (95%), Gaps = 18/423 (4%)
Query: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN 60
MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN
Sbjct: 1 MASDDFDIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSN 60
Query: 61 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYR 120
RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATG
Sbjct: 61 RSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATG-- 118
Query: 121 YGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR 180
EPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR
Sbjct: 119 ----------------EPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVR 162
Query: 181 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ 240
IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ
Sbjct: 163 IISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQ 222
Query: 241 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC 300
KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC
Sbjct: 223 KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSEC 282
Query: 301 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG 360
ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG
Sbjct: 283 ARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEG 342
Query: 361 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP 420
AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP
Sbjct: 343 AGIQLPSTAAAAAAAAAQAAALQLNGAVPLGALNPAALTALSPALNLASQCFQLSSLFTP 402
Query: 421 QTM 423
QTM
Sbjct: 403 QTM 405
>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
Length = 524
Score = 461 bits (1186), Expect = e-130
Identities = 266/449 (59%), Positives = 314/449 (69%), Gaps = 55/449 (12%)
Query: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66
DI IEAMLEAPYKK+E++ ++ S S S + S ++ R R RD
Sbjct: 4 DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRS---KSKERKRSRD 60
Query: 67 RYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSP------------- 113
R R++ S+SR R RSRS +RR S SRSRD R R YRSP
Sbjct: 61 RERKK-SKSRE-----RKRSRSKERRR-SRSRSRDRRFRGR--YRSPYSGPKFNSAIRGK 111
Query: 114 -----PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLED 168
+ R SKSP ++KSPVREP+DNL+PEERDARTVFCMQLAARIRPRDLE+
Sbjct: 112 IGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEE 171
Query: 169 FFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAE 228
FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAE
Sbjct: 172 FFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAE 231
Query: 229 KNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288
KNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSK
Sbjct: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
Query: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDL 344
GYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + +F D D+ +DL
Sbjct: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDL 351
Query: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL----------- 393
G+ GR QLMA+LAEG G+Q+P A ALQ++G++ GA+
Sbjct: 352 GTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVADLQTRLSQQT 401
Query: 394 NPAALTALSPALNLASQCFQLSSLFTPQT 422
+AL A + LA+QCFQLS++F PQT
Sbjct: 402 EASALAAAASVQPLATQCFQLSNMFNPQT 430
>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
Length = 530
Score = 459 bits (1180), Expect = e-129
Identities = 266/455 (58%), Positives = 314/455 (69%), Gaps = 61/455 (13%)
Query: 7 DIVIEAMLEAPYKKEEDEQQRKEVKKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRD 66
DI IEAMLEAPYKK+E++ ++ S S S + S ++ R R RD
Sbjct: 4 DIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRS---KSKERKRSRD 60
Query: 67 RYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSP------------- 113
R R++ S+SR R RSRS +RR S SRSRD R R YRSP
Sbjct: 61 RERKK-SKSRE-----RKRSRSKERRR-SRSRSRDRRFRGR--YRSPYSGPKFNSAIRGK 111
Query: 114 -----PLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLED 168
+ R SKSP ++KSPVREP+DNL+PEERDARTVFCMQLAARIRPRDLE+
Sbjct: 112 IGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQLAARIRPRDLEE 171
Query: 169 FFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAE 228
FFS VGKVRDVR+ISDRNSRRSKGIAYVEF ++ SVPLAIGLTGQR+LGVPIIVQASQAE
Sbjct: 172 FFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAE 231
Query: 229 KNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288
KNR AAMANNLQKG+ GPMRLYVGSLHFNITEDMLRGIFEPFG+I++I LM DS+TGRSK
Sbjct: 232 KNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSK 291
Query: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQ----ELDL 344
GYGFITFSDSECA++ALEQLNGFELAGRPM+VGHVTER D + +F D D+ +DL
Sbjct: 292 GYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASSASSFLDSDELERTGIDL 351
Query: 345 GSAGGRFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQLNGAVPLGAL----------- 393
G+ GR QLMA+LAEG G+Q+P A ALQ++G++ GA+
Sbjct: 352 GTT-GRLQLMARLAEGTGLQIPPAA---------QQALQMSGSLAFGAVAEFSFVIDLQT 401
Query: 394 ------NPAALTALSPALNLASQCFQLSSLFTPQT 422
+AL A + LA+QCFQLS++F PQT
Sbjct: 402 RLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT 436
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 94.7 bits (234), Expect = 1e-19
Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%)
Query: 138 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 193
P+ +++ + + A + C I ED F+ G ++ + + D + + KG
Sbjct: 70 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 129
Query: 194 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 253
A+VE+ ++ LA+ +LG I + + + + L + R+YV S
Sbjct: 130 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 189
Query: 254 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 313
+H ++++D ++ +FE FGKI + L +D TG+ KGYGFI + ++ ++ A+ +N F+L
Sbjct: 190 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 249
Query: 314 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 373
G+ +RVG +T P M L LP AA AA
Sbjct: 250 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 283
Query: 374 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 408
AAA Q + GA LG L L +SPAL LA
Sbjct: 284 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 318
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 94.7 bits (234), Expect = 1e-19
Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%)
Query: 138 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 193
P+ +++ + + A + C I ED F+ G ++ + + D + + KG
Sbjct: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
Query: 194 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 253
A+VE+ ++ LA+ +LG I + + + + L + R+YV S
Sbjct: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232
Query: 254 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 313
+H ++++D ++ +FE FGKI + L +D TG+ KGYGFI + ++ ++ A+ +N F+L
Sbjct: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292
Query: 314 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 373
G+ +RVG +T P M L LP AA AA
Sbjct: 293 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 326
Query: 374 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 408
AAA Q + GA LG L L +SPAL LA
Sbjct: 327 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 361
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 92.4 bits (228), Expect = 7e-19
Identities = 70/241 (29%), Positives = 113/241 (46%), Gaps = 30/241 (12%)
Query: 170 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 229
F+ G ++ + + D + + KG A+VE+ ++ LA+ +LG I +
Sbjct: 132 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 191
Query: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289
+ + + L + R+YV S+H ++++D ++ +FE FGKI + L +D TG+ KG
Sbjct: 192 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 251
Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGG 349
YGFI + ++ ++ A+ +N F+L G+ +RVG +T P
Sbjct: 252 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA---------VTPP------------- 289
Query: 350 RFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQ--LNGAVPLGALNPAALTALSPALNL 407
M L LP AA AAAAA Q + GA LG L L +SPAL L
Sbjct: 290 ----MPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTL 343
Query: 408 A 408
A
Sbjct: 344 A 344
Score = 68.2 bits (165), Expect = 1e-11
Identities = 37/98 (37%), Positives = 56/98 (57%)
Query: 224 ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSD 283
A Q ++ MA Q+ R+YVGS+++ + ED +R F PFG I +I + DS
Sbjct: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148
Query: 284 TGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVG 321
T + KG+ F+ + E A+ ALEQ+N L GR ++VG
Sbjct: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186
Score = 35.0 bits (79), Expect = 0.13
Identities = 15/65 (23%), Positives = 32/65 (49%)
Query: 139 VDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 198
+D L+ E R ++ + + D++ F A GK++ + D + + KG ++E+
Sbjct: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257
Query: 199 CEIQS 203
+ QS
Sbjct: 258 EKAQS 262
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 83.6 bits (205), Expect = 3e-16
Identities = 86/332 (25%), Positives = 139/332 (41%), Gaps = 83/332 (25%)
Query: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171
S P + G+ G S SP P+++ DA +F Q+ + +DL+ F
Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75
Query: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNR 231
GK+ ++ ++ DR + KG A++ +CE +S A Q++ E+
Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKA---------------QSALHEQKT 120
Query: 232 LAAMANNLQ------KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTG 285
L M +Q + G +L+VG L+ +ED +R +FE FG I+ +++ D G
Sbjct: 121 LPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-G 179
Query: 286 RSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE- 341
SKG F+ +S A+ A+ L+G ++ + G + + F D D+E
Sbjct: 180 NSKGCAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKER 226
Query: 342 -------------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAA 374
+ G+ G Q LMA +A+G L AA AAA
Sbjct: 227 TMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAA 284
Query: 375 AAAQAAALQLNG--AVPL----GALNPAALTA 400
Q AAL +NG A P+ G P +TA
Sbjct: 285 QMQQMAALNMNGLAAAPMTPTSGGSTPPGITA 316
>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
sapiens]
Length = 485
Score = 83.6 bits (205), Expect = 3e-16
Identities = 85/327 (25%), Positives = 142/327 (43%), Gaps = 64/327 (19%)
Query: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171
S P + G+ G S SP P+++ DA +F Q+ + +DL+ F
Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75
Query: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 229
GK+ ++ ++ DR + KG A++ +CE +S A ++ L G+ +Q A+
Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135
Query: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289
++ L++ +L+VG L+ +ED +R +FE FG I+ +++ D G SKG
Sbjct: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193
Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 341
F+ +S A+ A+ L+G ++ + G + + F D D+E
Sbjct: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240
Query: 342 ---------------LDLGSAGGRFQ-------LMAKLAEGAGIQLPSTAAAAAAAAAQA 379
+ G+ G Q LMA +A+G L AA AAA Q
Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGG--YLNPMAAFAAAQMQQM 298
Query: 380 AALQLNG--AVPL----GALNPAALTA 400
AAL +NG A P+ G P +TA
Sbjct: 299 AALNMNGLAAAPMTPTSGGSTPPGITA 325
Score = 28.9 bits (63), Expect = 9.2
Identities = 9/31 (29%), Positives = 22/31 (70%)
Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRV 320
+GF++F + A+ A++ +NGF++ + ++V
Sbjct: 443 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 473
>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
sapiens]
Length = 486
Score = 83.2 bits (204), Expect = 4e-16
Identities = 85/328 (25%), Positives = 142/328 (43%), Gaps = 65/328 (19%)
Query: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171
S P + G+ G S SP P+++ DA +F Q+ + +DL+ F
Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75
Query: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQR--LLGVPIIVQASQAEK 229
GK+ ++ ++ DR + KG A++ +CE +S A ++ L G+ +Q A+
Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135
Query: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289
++ L++ +L+VG L+ +ED +R +FE FG I+ +++ D G SKG
Sbjct: 136 ESRGG-SSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNSKG 193
Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE----- 341
F+ +S A+ A+ L+G ++ + G + + F D D+E
Sbjct: 194 CAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTMRR 240
Query: 342 ---------------LDLGSAGGRFQ--------LMAKLAEGAGIQLPSTAAAAAAAAAQ 378
+ G+ G Q LMA +A+G L AA AAA Q
Sbjct: 241 MQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGG--YLNPMAAFAAAQMQQ 298
Query: 379 AAALQLNG--AVPL----GALNPAALTA 400
AAL +NG A P+ G P +TA
Sbjct: 299 MAALNMNGLAAAPMTPTSGGSTPPGITA 326
Score = 28.9 bits (63), Expect = 9.2
Identities = 9/31 (29%), Positives = 22/31 (70%)
Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRV 320
+GF++F + A+ A++ +NGF++ + ++V
Sbjct: 444 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 474
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 82.4 bits (202), Expect = 7e-16
Identities = 51/178 (28%), Positives = 99/178 (55%), Gaps = 8/178 (4%)
Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-L 210
VF L I + L + FSA GK+ +++SD + SKG A+V F + AI +
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
Query: 211 TGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPF 270
G+ L G + V + K+R A + + + +Y+ + ++ ++ L+ +F +
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFTN----VYIKNFGGDMDDERLKDVFSKY 213
Query: 271 GKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328
GK ++ +M DS +G+SKG+GF++F E A++A+E++NG ++ G+ + VG ++++
Sbjct: 214 GKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVE 270
Score = 74.7 bits (182), Expect = 1e-13
Identities = 50/163 (30%), Positives = 88/163 (53%), Gaps = 12/163 (7%)
Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224
L+D FS GK V++++D +S +SKG +V F ++ A+ + G+ + G I V
Sbjct: 206 LKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR 264
Query: 225 SQAEKNRLAAMANNLQ-------KGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIV 277
+Q + R A + + +G G ++LY+ +L I ++ LR F FG I +
Sbjct: 265 AQKKVERQAELKQMFEQLKRERIRGCQG-VKLYIKNLDDTIDDEKLRNEFSSFGSISRVK 323
Query: 278 LMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 320
+M++ G+SKG+G I FS E A +A+ ++NG L +P+ +
Sbjct: 324 VMQEE--GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364
Score = 65.9 bits (159), Expect = 7e-11
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 11/159 (6%)
Query: 170 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 229
FS VG V +RI D+ +RRS G AYV F ++ A+ ++ + +
Sbjct: 30 FSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDII---------KGKS 80
Query: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289
RL + G +++ +L +I L F FGKI + +M D D G SKG
Sbjct: 81 IRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD-DQG-SKG 138
Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328
Y F+ F + A RA+E++NG L G + VG R D
Sbjct: 139 YAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKD 177
Score = 51.6 bits (122), Expect = 1e-06
Identities = 26/72 (36%), Positives = 43/72 (59%)
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LYVG LH ++TED+L F G + +I + +D T RS GY ++ F A++AL+ +
Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
Query: 309 NGFELAGRPMRV 320
N + G+ +R+
Sbjct: 72 NFDIIKGKSIRL 83
>gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo
sapiens]
Length = 484
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/329 (26%), Positives = 142/329 (43%), Gaps = 69/329 (20%)
Query: 112 SPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFS 171
S P + G+ G S SP P+++ DA +F Q+ + +DL+ F
Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKD---------HDAIKLFIGQIPRNLDEKDLKPLFE 75
Query: 172 AVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLA-IGLTGQRLL---GVPIIVQASQA 227
GK+ ++ ++ DR + KG A++ +CE +S A L Q+ L PI V+ + +
Sbjct: 76 EFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADS 135
Query: 228 EKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRS 287
E ++ + +L+VG L+ +ED +R +FE FG I+ +++ D G S
Sbjct: 136 ESRG----GSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPD-GNS 190
Query: 288 KGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD---ITFPDGDQE--- 341
KG F+ +S A+ A+ L+G ++ + G + + F D D+E
Sbjct: 191 KGCAFVKYSSHAEAQAAINALHG-------------SQTMPGASSSLVVKFADTDKERTM 237
Query: 342 -----------------LDLGSAGGRFQ-------LMAKLAEGAGIQLPSTAAAAAAAAA 377
+ G+ G Q LMA +A+G L AA AAA
Sbjct: 238 RRMQQMAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGG--YLNPMAAFAAAQMQ 295
Query: 378 QAAALQLNG--AVPL----GALNPAALTA 400
Q AAL +NG A P+ G P +TA
Sbjct: 296 QMAALNMNGLAAAPMTPTSGGSTPPGITA 324
Score = 28.9 bits (63), Expect = 9.2
Identities = 9/31 (29%), Positives = 22/31 (70%)
Query: 290 YGFITFSDSECARRALEQLNGFELAGRPMRV 320
+GF++F + A+ A++ +NGF++ + ++V
Sbjct: 442 FGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 472
>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
Length = 288
Score = 80.5 bits (197), Expect = 3e-15
Identities = 61/170 (35%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Query: 31 KKDYPSNTTSSTSNSGNETSGSSTIGETSNRSRDRDRYRRRNSRSRSPGRQCRHRSRSWD 90
+++Y + S S SG+ + T RSR ++ RR S+SRS + R RSR
Sbjct: 6 EQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRS-ESRSRSRRSS 64
Query: 91 RRH--GSESRSRDHRREDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERD 148
RRH S SRSR HRR RS + YR HS S H + R + +P+
Sbjct: 65 RRHYTRSRSRSRSHRRS-----RSRSYSRDYRRRHSHS-HSPMSTRRRHVGNRANPDPNC 118
Query: 149 ARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 198
VF + L RDL + FS G + DV I+ D+ SRRS+G A+V F
Sbjct: 119 CLGVFGLSLYTT--ERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYF 166
Score = 51.6 bits (122), Expect = 1e-06
Identities = 27/72 (37%), Positives = 42/72 (58%)
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
L V L TE LR +F +G I ++ ++ D + RS+G+ F+ F + + A+ A E+
Sbjct: 120 LGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERA 179
Query: 309 NGFELAGRPMRV 320
NG EL GR +RV
Sbjct: 180 NGMELDGRRIRV 191
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 79.0 bits (193), Expect = 8e-15
Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 118 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 163
GY Y + + P E++ P+R P R + VF L I
Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112
Query: 164 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 222
+ L D FSA G + +++ D N SKG A+V F ++ AI + G L + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
Query: 223 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 282
++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D
Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226
Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328
+ G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++
Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 76.3 bits (186), Expect = 5e-14
Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%)
Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195
+E L + ++ V+ + L++ FS GK V+++ D N + SKG +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235
Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 248
V + + + A+ + G+ + G I V +Q + R A + ++ +
Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353
Query: 309 NGFELAGRPMRV 320
NG + +P+ V
Sbjct: 354 NGRIVGSKPLYV 365
Score = 61.2 bits (147), Expect = 2e-09
Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%)
Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224
L + FS G V +R+ D +RRS G AYV F + A+ + + G PI +
Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86
Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284
SQ + +L+K G +++ +L +I L F FG I + ++ D
Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134
Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326
SKGY F+ F E A +A+E++NG L R + VG R
Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176
Score = 58.2 bits (139), Expect = 1e-08
Identities = 29/72 (40%), Positives = 43/72 (59%)
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 309 NGFELAGRPMRV 320
N + G+P+R+
Sbjct: 73 NFDVIKGKPIRI 84
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 79.0 bits (193), Expect = 8e-15
Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 118 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 163
GY Y + + P E++ P+R P R + VF L I
Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112
Query: 164 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 222
+ L D FSA G + +++ D N SKG A+V F ++ AI + G L + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
Query: 223 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 282
++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D
Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226
Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328
+ G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++
Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 76.3 bits (186), Expect = 5e-14
Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%)
Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195
+E L + ++ V+ + L++ FS GK V+++ D N + SKG +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235
Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 248
V + + + A+ + G+ + G I V +Q + R A + ++ +
Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353
Query: 309 NGFELAGRPMRV 320
NG + +P+ V
Sbjct: 354 NGRIVGSKPLYV 365
Score = 61.2 bits (147), Expect = 2e-09
Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%)
Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224
L + FS G V +R+ D +RRS G AYV F + A+ + + G PI +
Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86
Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284
SQ + +L+K G +++ +L +I L F FG I + ++ D
Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134
Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326
SKGY F+ F E A +A+E++NG L R + VG R
Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176
Score = 58.2 bits (139), Expect = 1e-08
Identities = 29/72 (40%), Positives = 43/72 (59%)
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 309 NGFELAGRPMRV 320
N + G+P+R+
Sbjct: 73 NFDVIKGKPIRI 84
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 79.0 bits (193), Expect = 8e-15
Identities = 59/226 (26%), Positives = 110/226 (48%), Gaps = 22/226 (9%)
Query: 118 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 163
GY Y + + P E++ P+R P R + VF L I
Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDN 112
Query: 164 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 222
+ L D FSA G + +++ D N SKG A+V F ++ AI + G L + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
Query: 223 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 282
++ K R A + ++ +Y+ + + ++ L+ +F FGK ++ +M+D
Sbjct: 171 GRFKSRKEREAELGAKAKEFTN----VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP 226
Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLD 328
+ G+SKG+GF+++ E A +A+E++NG E++G+ + VG ++++
Sbjct: 227 N-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
Score = 76.3 bits (186), Expect = 5e-14
Identities = 51/192 (26%), Positives = 93/192 (48%), Gaps = 10/192 (5%)
Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195
+E L + ++ V+ + L++ FS GK V+++ D N + SKG +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGK-SKGFGF 235
Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQK------GNGGPMR 248
V + + + A+ + G+ + G I V +Q + R A + ++ +
Sbjct: 236 VSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN 295
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LY+ +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353
Query: 309 NGFELAGRPMRV 320
NG + +P+ V
Sbjct: 354 NGRIVGSKPLYV 365
Score = 61.2 bits (147), Expect = 2e-09
Identities = 49/162 (30%), Positives = 75/162 (46%), Gaps = 13/162 (8%)
Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224
L + FS G V +R+ D +RRS G AYV F + A+ + + G PI +
Sbjct: 27 LYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMW 86
Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284
SQ + +L+K G +++ +L +I L F FG I + ++ D
Sbjct: 87 SQRDP--------SLRKSGVG--NVFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134
Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326
SKGY F+ F E A +A+E++NG L R + VG R
Sbjct: 135 NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176
Score = 58.2 bits (139), Expect = 1e-08
Identities = 29/72 (40%), Positives = 43/72 (59%)
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LYVG LH ++TE ML F P G + +I + +D T RS GY ++ F A RAL+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 309 NGFELAGRPMRV 320
N + G+P+R+
Sbjct: 73 NFDVIKGKPIRI 84
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 77.4 bits (189), Expect = 2e-14
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 11/183 (6%)
Query: 145 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 204
++ RT++ L+ + + FS +G + ++I++ S + +VEF E +
Sbjct: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDA 61
Query: 205 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 263
A+ + G+++LG + K A ++ +K ++VG L IT + +
Sbjct: 62 AAALAAMNGRKILGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 113
Query: 264 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 323
+ F PFGKI + ++KD TG+SKGYGF++F + A A+ + G L GR +R
Sbjct: 114 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 173
Query: 324 TER 326
T +
Sbjct: 174 TRK 176
Score = 68.2 bits (165), Expect = 1e-11
Identities = 48/182 (26%), Positives = 78/182 (42%), Gaps = 23/182 (12%)
Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 211
VF L+ I D++ F+ GK+ D R++ D + +SKG +V F AI
Sbjct: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
Query: 212 GQRLLG--------------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFN 257
G + LG P Q + ++ R + N N +Y G +
Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKN---CTVYCGGIASG 215
Query: 258 ITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRP 317
+T+ ++R F PFG+I I + + KGY F+ FS E A A+ +NG + G
Sbjct: 216 LTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHV 269
Query: 318 MR 319
++
Sbjct: 270 VK 271
Score = 40.4 bits (93), Expect = 0.003
Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 239 LQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDS 298
+ + +G P LYVG+L ++TE ++ +F G + ++ + + + Y F+ F +
Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEH 58
Query: 299 ECARRALEQLNGFELAGRPMRVGHVT 324
A AL +NG ++ G+ ++V T
Sbjct: 59 RDAAAALAAMNGRKILGKEVKVNWAT 84
Score = 29.6 bits (65), Expect = 5.4
Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 15/98 (15%)
Query: 111 RSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFF 170
R PP + ++K F + V+ SP+ TV+C +A+ + + + F
Sbjct: 175 RKPPAPKSTQENNTKQLRFEDV------VNQSSPKNC---TVYCGGIASGLTDQLMRQTF 225
Query: 171 SAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAI 208
S G++ ++R+ + KG ++V F +S AI
Sbjct: 226 SPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAI 257
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 77.4 bits (189), Expect = 2e-14
Identities = 48/183 (26%), Positives = 92/183 (50%), Gaps = 11/183 (6%)
Query: 145 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 204
E+ +T++ L+ + + FS +G ++ ++I D + + +VEF E +
Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
Query: 205 PLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDML 263
A+ + G++++G + K A ++ +K ++VG L IT + +
Sbjct: 60 AAALAAMNGRKIMGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 111
Query: 264 RGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHV 323
+ F PFG+I + ++KD TG+SKGYGF++F + A A++Q+ G L GR +R
Sbjct: 112 KAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWA 171
Query: 324 TER 326
T +
Sbjct: 172 TRK 174
Score = 67.8 bits (164), Expect = 2e-11
Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 211
VF L+ I D++ F+ G++ D R++ D + +SKG +V F AI
Sbjct: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
Query: 212 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260
G + LG P +++ + + + + + +Y G + +TE
Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
Query: 261 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 320
++R F PFG+I I + D KGY F+ F+ E A A+ +NG + G ++
Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 270
Query: 321 GHVTERLD 328
E LD
Sbjct: 271 YWGKETLD 278
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 77.0 bits (188), Expect = 3e-14
Identities = 56/187 (29%), Positives = 88/187 (47%), Gaps = 14/187 (7%)
Query: 142 LSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEI 201
+S +DA TV+ L ++ L + F G V + + DR + + +G +VEF
Sbjct: 6 ISERNQDA-TVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
Query: 202 QSVPLAIGLTGQ-RLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260
+ AI + +L G PI V + A L AN +++G+L I E
Sbjct: 65 EDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGAN-----------IFIGNLDPEIDE 113
Query: 261 DMLRGIFEPFGKI-DNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 319
+L F FG I +M+D DTG SKGY FI F+ + + A+E +NG L RP+
Sbjct: 114 KLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPIT 173
Query: 320 VGHVTER 326
V + ++
Sbjct: 174 VSYAFKK 180
Score = 58.9 bits (141), Expect = 8e-09
Identities = 34/98 (34%), Positives = 55/98 (56%), Gaps = 3/98 (3%)
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
+YVG L ++E +L +F G + N + KD TG+ +GYGF+ F E A A++ +
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 309 NGFELAGRPMRVGHVT---ERLDGGTDITFPDGDQELD 343
N +L G+P+RV + + LD G +I + D E+D
Sbjct: 75 NMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEID 112
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 77.0 bits (188), Expect = 3e-14
Identities = 59/231 (25%), Positives = 112/231 (48%), Gaps = 22/231 (9%)
Query: 118 GYRYGHSKSPHFREKS------------PVREPVDNLSPEERDART--VFCMQLAARIRP 163
GY Y + + P E++ PVR P R + +F L I
Sbjct: 53 GYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDN 112
Query: 164 RDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIV 222
+ L D FSA G + +++ D N SKG +V F ++ AI + G L + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFV 170
Query: 223 QASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDS 282
++ K R A + ++ +Y+ + ++ ++ L+ +F FG ++ +M D
Sbjct: 171 GRFKSRKEREAELGARAKEFTN----VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD- 225
Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDI 333
++G+SKG+GF++F E A++A++++NG EL G+ + VG ++++ T++
Sbjct: 226 ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL 276
Score = 72.8 bits (177), Expect = 6e-13
Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 10/192 (5%)
Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195
+E L ++ V+ + L+D F G V++++D S +SKG +
Sbjct: 177 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 235
Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM------R 248
V F + A+ + G+ L G I V +Q + R + ++ +
Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVN 295
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LYV +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++
Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353
Query: 309 NGFELAGRPMRV 320
NG +A +P+ V
Sbjct: 354 NGRIVATKPLYV 365
Score = 65.1 bits (157), Expect = 1e-10
Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 13/162 (8%)
Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224
L + FS G + +R+ D +RRS G AYV F + A+ + + G P+ +
Sbjct: 27 LYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMW 86
Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDT 284
SQ + +L+K G +++ +L +I L F FG I + ++ D
Sbjct: 87 SQRDP--------SLRKSGVG--NIFIKNLDKSIDNKALYDTFSAFGNILSCKVV--CDE 134
Query: 285 GRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326
SKGYGF+ F E A RA+E++NG L R + VG R
Sbjct: 135 NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSR 176
Score = 57.8 bits (138), Expect = 2e-08
Identities = 30/72 (41%), Positives = 43/72 (59%)
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LYVG LH ++TE ML F P G I +I + +D T RS GY ++ F A RAL+ +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 309 NGFELAGRPMRV 320
N + G+P+R+
Sbjct: 73 NFDVIKGKPVRI 84
>gi|20373175 musashi 2 isoform a [Homo sapiens]
Length = 328
Score = 76.6 bits (187), Expect = 4e-14
Identities = 64/263 (24%), Positives = 114/263 (43%), Gaps = 23/263 (8%)
Query: 146 ERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVP 205
+ D +F L+ + P L D+FS G++R+ ++ D ++RS+G +V F + SV
Sbjct: 17 QHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV- 75
Query: 206 LAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRG 265
++LG P S+ ++A K +++VG L N + ++
Sbjct: 76 -------DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQ 128
Query: 266 IFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTE 325
FE FGK+++ +LM D T R +G+GF+TF + + + E ++ E+ + +
Sbjct: 129 YFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE-IHFHEINNKMVECKKAQP 187
Query: 326 RLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGI----QLPSTAAAAAAAAAQAAA 381
+ ++ FP G + G A G M G G+ +T A +
Sbjct: 188 K-----EVMFPPGTR----GRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYG 238
Query: 382 LQLNGAVPLGALNPAALTALSPA 404
Q G P A P A A++ A
Sbjct: 239 YQFPG-FPAAAYGPVAAAAVAAA 260
Score = 53.9 bits (128), Expect = 3e-07
Identities = 25/80 (31%), Positives = 42/80 (52%)
Query: 228 EKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRS 287
E N + + P ++++G L + + D LR F FG+I ++M+D T RS
Sbjct: 2 EANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRS 61
Query: 288 KGYGFITFSDSECARRALEQ 307
+G+GF+TF+D + L Q
Sbjct: 62 RGFGFVTFADPASVDKVLGQ 81
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 75.9 bits (185), Expect = 7e-14
Identities = 49/187 (26%), Positives = 96/187 (51%), Gaps = 8/187 (4%)
Query: 145 EERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSV 204
E+ +T++ L+ + + FS +G ++ ++I D + + +VEF E +
Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHA 59
Query: 205 PLAIG-LTGQRLLGVPIIVQ----ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNIT 259
A+ + G++++G + V S +K+ ++ + Q+ ++VG L IT
Sbjct: 60 AAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDH-FHVFVGDLSPEIT 118
Query: 260 EDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMR 319
+ ++ F PFG+I + ++KD TG+SKGYGF++F + A A++Q+ G L GR +R
Sbjct: 119 TEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIR 178
Query: 320 VGHVTER 326
T +
Sbjct: 179 TNWATRK 185
Score = 67.8 bits (164), Expect = 2e-11
Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 211
VF L+ I D++ F+ G++ D R++ D + +SKG +V F AI
Sbjct: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
Query: 212 GQRLLG-----------VPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260
G + LG P +++ + + + + + +Y G + +TE
Sbjct: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
Query: 261 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRV 320
++R F PFG+I I + D KGY F+ F+ E A A+ +NG + G ++
Sbjct: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKC 281
Query: 321 GHVTERLD 328
E LD
Sbjct: 282 YWGKETLD 289
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 75.5 bits (184), Expect = 9e-14
Identities = 49/183 (26%), Positives = 96/183 (52%), Gaps = 8/183 (4%)
Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-L 210
+F L I + L D SA G + ++ D N SKG +V F ++ AI +
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG--SKGYGFVHFETHEAAERAIKKM 158
Query: 211 TGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPF 270
G L G + V ++ K R A + ++ +Y+ + ++ ++ L+ +F F
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFPN----VYIKNFGEDMDDERLKDLFGKF 214
Query: 271 GKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGG 330
G ++ +M D ++G+SKG+GF++F E A++A++++NG EL G+ + VG ++++
Sbjct: 215 GPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273
Query: 331 TDI 333
T++
Sbjct: 274 TEL 276
Score = 73.2 bits (178), Expect = 4e-13
Identities = 53/192 (27%), Positives = 90/192 (46%), Gaps = 10/192 (5%)
Query: 136 REPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAY 195
+E L ++ V+ + L+D F G V++++D S +SKG +
Sbjct: 177 KEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGF 235
Query: 196 VEFCEIQSVPLAIG-LTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPM------R 248
V F + A+ + G+ L G I V +Q + R + ++ +
Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVN 295
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LYV +L I ++ LR F PFG I + +M + GRSKG+GF+ FS E A +A+ ++
Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353
Query: 309 NGFELAGRPMRV 320
NG +A +P+ V
Sbjct: 354 NGRIVATKPLYV 365
Score = 57.4 bits (137), Expect = 2e-08
Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 17/164 (10%)
Query: 166 LEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIG-LTGQRLLGVPIIVQA 224
L + FS G + +RI D + S AYV F + A+ + + G P+ +
Sbjct: 27 LYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTMNFDVIKGKPVRIMW 86
Query: 225 SQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKI--DNIVLMKDS 282
SQ + +L+K G ++V +L +I L FG I N+V
Sbjct: 87 SQRDP--------SLRKSGVG--NIFVKNLDKSINNKALYDTVSAFGNILSCNVV----C 132
Query: 283 DTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTER 326
D SKGYGF+ F E A RA++++NG L GR + VG R
Sbjct: 133 DENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSR 176
Score = 53.5 bits (127), Expect = 3e-07
Identities = 27/72 (37%), Positives = 42/72 (58%)
Query: 249 LYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQL 308
LYVG LH ++TE ML F P G I +I + +D T S Y ++ F ++ A AL+ +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72
Query: 309 NGFELAGRPMRV 320
N + G+P+R+
Sbjct: 73 NFDVIKGKPVRI 84
>gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo
sapiens]
Length = 420
Score = 74.7 bits (182), Expect = 1e-13
Identities = 69/260 (26%), Positives = 113/260 (43%), Gaps = 32/260 (12%)
Query: 62 SRDRDRYRRRNSRSRSPGRQC--------RHRSRSWDRRHGSES---RSRDHRREDRVHY 110
+R R +R+ ++ P R R R RRH S RS R
Sbjct: 50 ARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTAR 109
Query: 111 RSPPLATGYRYG----HSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDL 166
+ PP + +S F E S + N S ++D +F L+ +DL
Sbjct: 110 QHPPADSSVTMEDMNEYSNIEEFAEGSKI-----NASKNQQDDGKMFIGGLSWDTSKKDL 164
Query: 167 EDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQ 226
++ S G+V D I +D + RS+G +V F + SV + L +L G I + ++
Sbjct: 165 TEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAK 224
Query: 227 AEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGR 286
A KG P +++VG L + +E+ ++ F FG+I+NI L D+ T
Sbjct: 225 A------------LKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNE 272
Query: 287 SKGYGFITFSDSECARRALE 306
+G+ FIT++D E ++ LE
Sbjct: 273 RRGFCFITYTDEEPVKKLLE 292
>gi|25121993 musashi 2 isoform b [Homo sapiens]
Length = 251
Score = 74.7 bits (182), Expect = 1e-13
Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 8/155 (5%)
Query: 152 VFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLT 211
+F L+ + P L D+FS G++R+ ++ D ++RS+G +V F + SV
Sbjct: 19 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASV------- 71
Query: 212 GQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFG 271
++LG P S+ ++A K +++VG L N + ++ FE FG
Sbjct: 72 -DKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFG 130
Query: 272 KIDNIVLMKDSDTGRSKGYGFITFSDSECARRALE 306
K+++ +LM D T R +G+GF+TF + + + E
Sbjct: 131 KVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCE 165
Score = 52.0 bits (123), Expect = 1e-06
Identities = 22/60 (36%), Positives = 37/60 (61%)
Query: 248 RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 307
++++G L + + D LR F FG+I ++M+D T RS+G+GF+TF+D + L Q
Sbjct: 18 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77
>gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a
[Homo sapiens]
Length = 475
Score = 74.3 bits (181), Expect = 2e-13
Identities = 83/348 (23%), Positives = 135/348 (38%), Gaps = 83/348 (23%)
Query: 59 SNRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSE-SRSRDHRREDRVHYRSPPLAT 117
+ + RD++ R+ S SRS R + RSRS DRR+ + S SRD RR RS PL
Sbjct: 14 NKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRR------RSKPLTR 67
Query: 118 GYRYGHS---KSPHFREKSPVREPVD------------------------------NLSP 144
G + H +SP +K VR+ D ++P
Sbjct: 68 GAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTP 127
Query: 145 E----------------ERDARTVFCMQLAARIRPRDLEDFFSAVGK-----------VR 177
+ R AR ++ + I + DFF+A + V
Sbjct: 128 DGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVL 187
Query: 178 DVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMAN 237
V+I D+N A++EF + A+ G G + ++ + L M+
Sbjct: 188 AVQINQDKN------FAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPH-DYQPLPGMSE 240
Query: 238 NLQKGNGGPM---------RLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSK 288
N G + +L++G L + +D ++ + FG + L+KDS TG SK
Sbjct: 241 NPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSK 300
Query: 289 GYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFP 336
GY F + D +A+ LNG +L + + V + T ++ P
Sbjct: 301 GYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPP 348
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 74.3 bits (181), Expect = 2e-13
Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 8/170 (4%)
Query: 131 EKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRS 190
EK+ P++ E+ R +F L+ L +++ GK+ D ++ D S+RS
Sbjct: 2 EKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRS 61
Query: 191 KGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMR-L 249
+G +V F + V A+ P + E R A + + G ++ L
Sbjct: 62 RGFGFVTFSSMAEVDAAMAAR-------PHSIDGRVVEPKRAVAREESGKPGAHVTVKKL 114
Query: 250 YVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSE 299
+VG + + E LR FE +GKID I ++ D +G+ +G+GF+TF D +
Sbjct: 115 FVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD 164
>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
[Homo sapiens]
Length = 285
Score = 74.3 bits (181), Expect = 2e-13
Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 13/167 (7%)
Query: 141 NLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCE 200
N S E DA +F L+ +DL+D+F+ G+V D I D N+ RS+G ++ F +
Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120
Query: 201 IQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260
SV + RL G I + + AM + K +++VG L+ TE
Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167
Query: 261 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 307
+ +R F FG+I+ I L D + +G+ FITF + E ++ LE+
Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214
>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
[Homo sapiens]
Length = 332
Score = 74.3 bits (181), Expect = 2e-13
Identities = 51/167 (30%), Positives = 82/167 (49%), Gaps = 13/167 (7%)
Query: 141 NLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCE 200
N S E DA +F L+ +DL+D+F+ G+V D I D N+ RS+G ++ F +
Sbjct: 61 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 120
Query: 201 IQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITE 260
SV + RL G I + + AM + K +++VG L+ TE
Sbjct: 121 AASVEKVLDQKEHRLDGRVI-------DPKKAMAMKKDPVK------KIFVGGLNPEATE 167
Query: 261 DMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQ 307
+ +R F FG+I+ I L D + +G+ FITF + E ++ LE+
Sbjct: 168 EKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEK 214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,926,694
Number of Sequences: 37866
Number of extensions: 747464
Number of successful extensions: 8443
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 337
Number of HSP's successfully gapped in prelim test: 201
Number of HSP's that attempted gapping in prelim test: 5039
Number of HSP's gapped (non-prelim): 2024
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.