Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 116517224
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116517224 coiled-coil domain containing 144B [Homo sapiens]
(725 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116517224 coiled-coil domain containing 144B [Homo sapiens] 1483 0.0
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 1414 0.0
gi|239756753 PREDICTED: similar to coiled-coil domain containing... 449 e-126
gi|51972186 coiled-coil domain containing 144 family, N-terminal... 273 4e-73
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 188 1e-47
gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo... 167 3e-41
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 166 5e-41
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 134 2e-31
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 132 9e-31
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 132 9e-31
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 118 2e-26
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 117 4e-26
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 115 1e-25
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 114 3e-25
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 81 3e-15
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 80 5e-15
gi|113413200 PREDICTED: similar to protein expressed in prostate... 80 9e-15
gi|88953571 PREDICTED: similar to protein expressed in prostate,... 80 9e-15
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 79 1e-14
gi|134133226 protein expressed in prostate, ovary, testis, and p... 77 4e-14
gi|153791352 prostate, ovary, testis expressed protein on chromo... 77 4e-14
gi|239754871 PREDICTED: similar to Coiled-coil domain-containing... 76 1e-13
gi|239749410 PREDICTED: similar to Coiled-coil domain-containing... 76 1e-13
gi|239743545 PREDICTED: hypothetical protein XP_002342885 [Homo ... 76 1e-13
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 65 2e-10
gi|153792284 pote protein [Homo sapiens] 65 2e-10
gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens] 65 2e-10
gi|239747116 PREDICTED: hypothetical protein XP_002343915 isofor... 65 2e-10
gi|239747114 PREDICTED: hypothetical protein XP_002343914 isofor... 65 2e-10
gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ... 65 2e-10
>gi|116517224 coiled-coil domain containing 144B [Homo sapiens]
Length = 725
Score = 1483 bits (3839), Expect = 0.0
Identities = 725/725 (100%), Positives = 725/725 (100%)
Query: 1 MASWGGEKRGGAEGSPKLAVYATRKTRSVRSQEDQWYLGYPGDQWSSGFSYSWWKNSVGS 60
MASWGGEKRGGAEGSPKLAVYATRKTRSVRSQEDQWYLGYPGDQWSSGFSYSWWKNSVGS
Sbjct: 1 MASWGGEKRGGAEGSPKLAVYATRKTRSVRSQEDQWYLGYPGDQWSSGFSYSWWKNSVGS 60
Query: 61 ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLV 120
ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLV
Sbjct: 61 ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLV 120
Query: 121 PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPENQSATKE 180
PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPENQSATKE
Sbjct: 121 PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPENQSATKE 180
Query: 181 LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDLELTSEEEQERLKGC 240
LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDLELTSEEEQERLKGC
Sbjct: 181 LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDLELTSEEEQERLKGC 240
Query: 241 ENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQ 300
ENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQ
Sbjct: 241 ENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQ 300
Query: 301 RFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISVSVVFET 360
RFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISVSVVFET
Sbjct: 301 RFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISVSVVFET 360
Query: 361 FPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKLHLHENKLDCDNDNKLGIGHIFSTDNN 420
FPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKLHLHENKLDCDNDNKLGIGHIFSTDNN
Sbjct: 361 FPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKLHLHENKLDCDNDNKLGIGHIFSTDNN 420
Query: 421 FHNDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLP 480
FHNDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLP
Sbjct: 421 FHNDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLP 480
Query: 481 PDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTE 540
PDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTE
Sbjct: 481 PDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTE 540
Query: 541 LSGTLTDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEP 600
LSGTLTDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEP
Sbjct: 541 LSGTLTDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEP 600
Query: 601 SEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLT 660
SEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLT
Sbjct: 601 SEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLT 660
Query: 661 VKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENGRKEMPICCII 720
VKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENGRKEMPICCII
Sbjct: 661 VKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENGRKEMPICCII 720
Query: 721 KIVNS 725
KIVNS
Sbjct: 721 KIVNS 725
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 1414 bits (3659), Expect = 0.0
Identities = 692/712 (97%), Positives = 697/712 (97%)
Query: 1 MASWGGEKRGGAEGSPKLAVYATRKTRSVRSQEDQWYLGYPGDQWSSGFSYSWWKNSVGS 60
MASWGGEKRGGAEGSPK AVYATRKT SV SQ DQWYLGYPGDQWSSGF YSWWKNSVGS
Sbjct: 1 MASWGGEKRGGAEGSPKPAVYATRKTPSVGSQGDQWYLGYPGDQWSSGFPYSWWKNSVGS 60
Query: 61 ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLV 120
ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEH+LAPGDTGVDKRDRKKSIQQLV
Sbjct: 61 ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHILAPGDTGVDKRDRKKSIQQLV 120
Query: 121 PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPENQSATKE 180
PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKV DK PSVSPSMPENQSATKE
Sbjct: 121 PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVDDKCPSVSPSMPENQSATKE 180
Query: 181 LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDLELTSEEEQERLKGC 240
LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQD ELTSEEEQERLKGC
Sbjct: 181 LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDSELTSEEEQERLKGC 240
Query: 241 ENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQ 300
ENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQ
Sbjct: 241 ENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQ 300
Query: 301 RFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISVSVVFET 360
RFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISVSVVFET
Sbjct: 301 RFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISVSVVFET 360
Query: 361 FPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKLHLHENKLDCDNDNKLGIGHIFSTDNN 420
FPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSK HLHENKLDCDNDNK GIGHIFSTD N
Sbjct: 361 FPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKFHLHENKLDCDNDNKPGIGHIFSTDKN 420
Query: 421 FHNDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLP 480
FHNDASTKKARNPEVV VEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLP
Sbjct: 421 FHNDASTKKARNPEVVMVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLP 480
Query: 481 PDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTE 540
PDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKE+VQLHK+VEEEMEKHRSNSTE
Sbjct: 481 PDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTE 540
Query: 541 LSGTLTDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEP 600
LSGTLTDGTTVGNDDDGLNQQIPRKEN EHDRPADKT+NEKN+VKNQIYPEADFADSMEP
Sbjct: 541 LSGTLTDGTTVGNDDDGLNQQIPRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEP 600
Query: 601 SEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLT 660
SEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLT
Sbjct: 601 SEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLT 660
Query: 661 VKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENGRK 712
VKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQEN K
Sbjct: 661 VKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEK 712
Score = 30.0 bits (66), Expect = 7.9
Identities = 46/208 (22%), Positives = 81/208 (38%), Gaps = 20/208 (9%)
Query: 503 KNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD------- 555
KN E++ L+L+++N +L E E+ E +G D T
Sbjct: 1082 KNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHL 1141
Query: 556 DGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEA-DFADSMEPSEIASEDCELSHSV 614
D N+ + ++ + K K K Q+ E + ME + + E
Sbjct: 1142 DAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHK-- 1199
Query: 615 YENFMLLIEQLRMEYKDS---ASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVS 671
+L+ E+ R E ++ A L + E L++L+ D T QME +
Sbjct: 1200 ----LLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLRE---DNTTSIKTQMELTIK 1252
Query: 672 VLQNELSETKKTKLQLELQKIEWEKELY 699
L++E+S K ++ ++E KELY
Sbjct: 1253 DLESEISRIKTSQADFNKTELERYKELY 1280
>gi|239756753 PREDICTED: similar to coiled-coil domain containing
144A [Homo sapiens]
Length = 226
Score = 449 bits (1154), Expect = e-126
Identities = 215/225 (95%), Positives = 217/225 (96%)
Query: 1 MASWGGEKRGGAEGSPKLAVYATRKTRSVRSQEDQWYLGYPGDQWSSGFSYSWWKNSVGS 60
M SWGGEKRGGAEGSPK AVYATRKT SVRSQEDQWYLGYPGDQWSSGFSYSWWKNSVGS
Sbjct: 1 MVSWGGEKRGGAEGSPKPAVYATRKTGSVRSQEDQWYLGYPGDQWSSGFSYSWWKNSVGS 60
Query: 61 ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLV 120
ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVL PGDTGVDKRDRKKSIQQLV
Sbjct: 61 ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLVPGDTGVDKRDRKKSIQQLV 120
Query: 121 PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPENQSATKE 180
PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKV DK PSVSPSMPENQSATKE
Sbjct: 121 PEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVDDKCPSVSPSMPENQSATKE 180
Query: 181 LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQD 225
LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKE ++
Sbjct: 181 LGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEGNKE 225
>gi|51972186 coiled-coil domain containing 144 family, N-terminal
like [Homo sapiens]
Length = 221
Score = 273 bits (698), Expect = 4e-73
Identities = 131/138 (94%), Positives = 131/138 (94%)
Query: 1 MASWGGEKRGGAEGSPKLAVYATRKTRSVRSQEDQWYLGYPGDQWSSGFSYSWWKNSVGS 60
MASWGGEKRGGA GSPK AVYATRKT SV SQEDQWYL YPGDQWS GFSYSWWKNSVGS
Sbjct: 1 MASWGGEKRGGAGGSPKPAVYATRKTPSVGSQEDQWYLDYPGDQWSLGFSYSWWKNSVGS 60
Query: 61 ESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLV 120
ESKHGEGALDQ QHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLV
Sbjct: 61 ESKHGEGALDQLQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLV 120
Query: 121 PEYKEKQTPESLPQNNNP 138
PEYKEKQTPESLPQNNNP
Sbjct: 121 PEYKEKQTPESLPQNNNP 138
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 188 bits (478), Expect = 1e-47
Identities = 195/682 (28%), Positives = 305/682 (44%), Gaps = 122/682 (17%)
Query: 88 ARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTL 147
A SG + L V+ D+ +S QL+ EYKE++ P+ QN+N + +L
Sbjct: 186 AVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDESSEDSL 245
Query: 148 S--------DETCQRS--KNLKVGDKS---PSVSPSMPENQSATKELGQMNLTEREKMDT 194
S D++ S ++L K+ PS++ M +Q + K L T R
Sbjct: 246 SRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR----- 300
Query: 195 GVVLLSGNDTLHDLCQSQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEM 254
+GN TL + S + + + + L TS + Q C + T Q P++
Sbjct: 301 -----TGNRTLFEDRDS----DSQDEVVVESLPTTSIKVQ-----CFS---HPTYQSPDL 343
Query: 255 AKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPAC 314
+ + P + K E + G + +N + + I +
Sbjct: 344 LPKPSHKSL----ANPGLMKEEPT--KPGIAKKENGIDI-----------------IESA 380
Query: 315 PEEEPLLDNSTRGTDV-KDIPFNLTNNIP-GCEEEDASEISVSVVFETFPEQKEPSLKNI 372
P E+ DN T +V K+ ++ + + G EE+ S + E FP++
Sbjct: 381 PLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWDSESISENFPQK-------Y 433
Query: 373 IHPYYHPYSGSQEHV-------------CQSSSKLHLHENKLDCDNDNKLGIGHIFSTDN 419
+ P G ++++ C S S+ + KL+ + + + H+ S +
Sbjct: 434 VDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSR-NFKMAKLEDTRNVGMPVAHMESPER 492
Query: 420 NFH-------NDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPK 472
H D+ KA + V+ + E DL++ Q + GS NN +P+
Sbjct: 493 YLHLKPTIEMKDSVPNKAGGMK--DVQTSKAAEHDLEVASEEEQERE-GSENN----QPQ 545
Query: 473 LENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLAL-------KKEN----- 520
+E +++ +H+ D + ++ +++ +KEN
Sbjct: 546 VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKENKEYAS 605
Query: 521 ----VQLHKEVEEEMEKHRSNSTELS------GTLTDGTTVGNDDDGLNQQIPRKENEEH 570
+Q+ + E EK S + S LT G +DD L++ +E+
Sbjct: 606 SGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEI-----DEDE 660
Query: 571 DRPADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYK 630
RP KT+NEKNKVKNQI D D + SE ASEDCEL HS Y+NFMLLIEQL ME K
Sbjct: 661 GRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECK 720
Query: 631 DSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQ 690
DS SL +IQD CE LL+LK NHC+ LTVK+K+ME+ V+VLQ ELSETK+ K QLE Q
Sbjct: 721 DSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQ 780
Query: 691 KIEWEKELYDLRLALKQENGRK 712
K+EWE+EL LR +L QE ++
Sbjct: 781 KVEWERELCSLRFSLNQEEEKR 802
Score = 49.7 bits (117), Expect = 1e-05
Identities = 23/58 (39%), Positives = 37/58 (63%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDR 112
++S G + GEGA QP + VR DLG++H+AA +G+V V+ +L G++ RD+
Sbjct: 21 RSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDK 78
Score = 32.0 bits (71), Expect = 2.1
Identities = 90/490 (18%), Positives = 176/490 (35%), Gaps = 63/490 (12%)
Query: 66 EGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKKSIQQLVPEYKE 125
+GA D + D +D L + +SG+ +H P + ++Q + E
Sbjct: 566 DGATDDAEDD---DDDDGLIQKRKSGET---DHQQFPRKENKEYASSGPALQMKEVKSTE 619
Query: 126 KQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPENQSATKELGQMN 185
K+ S N+P + +L L+V D S E + K + N
Sbjct: 620 KEKRTSKESVNSPVFGKASLLTGGL-------LQVDDDSSLSEIDEDEGRPTKKTSNEKN 672
Query: 186 LTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDLELTSEEEQERLK-----GC 240
+ + + D + DL QS S+ A +D EL + + G
Sbjct: 673 KVKNQ--------IQSMDDVDDLTQS-------SETASEDCELPHSSYKNFMLLIEQLGM 717
Query: 241 ENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKS--EEMWIEQGKLEWK-NQLKLVINE 297
E K + + A C+R L ++K+ E + ++ K+E K N L+ ++E
Sbjct: 718 ECKDSVSLLKIQDAALSCER--------LLELKKNHCELLTVKIKKMEDKVNVLQRELSE 769
Query: 298 LKQRFGEIYEK---YKIPACPEEEPLLDNSTRGTDVKDIPFNLTNNIPGCEEEDASEISV 354
K+ ++ + ++ C L + + + + + EE+ E+ V
Sbjct: 770 TKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEV 829
Query: 355 SVVFETFPEQKEPSLKNI---IHPYYHPYSGSQEHVCQSSSKLHLHENKLD--CDNDNKL 409
E + E L+ + ++ + +Q + + + L + L ++
Sbjct: 830 KQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEI 889
Query: 410 GIGHIFSTDNNFHNDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSL 469
+ N H+ K + + E ++ KN NQ + + K +
Sbjct: 890 EMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIV 949
Query: 470 KPKLENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVN--TLEEEFLALKKENVQLHKE- 526
K K E+L ++ T L Q + ++ ++ T E L K EN + KE
Sbjct: 950 KEKNEDLQKTIKQNEET--------LTQTISQYNGRLSVLTAENAMLNSKLENEKQSKER 1001
Query: 527 VEEEMEKHRS 536
+E E+E + S
Sbjct: 1002 LEAEVESYHS 1011
>gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo
sapiens]
Length = 452
Score = 167 bits (423), Expect = 3e-41
Identities = 106/261 (40%), Positives = 143/261 (54%), Gaps = 11/261 (4%)
Query: 424 DASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLPPDS 483
++ K P ++ V ++ + + K N N+ + L EN
Sbjct: 192 ESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRFGRICQLLSDYKENQMPNNSSG 251
Query: 484 DRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSG 543
+ E L +++ Q+ K N+ E+ N +EVEEEM+KH SN+ LS
Sbjct: 252 NSNPEQDLKLTSEEEPQRLKGSENSQHEKVTQEPDINKDCDREVEEEMQKHGSNNVGLSE 311
Query: 544 TLTDGTTVGNDDDGL----------NQQIPRKENEEHDRPADKTANEKNKVKNQIYPEAD 593
LTDG GN D GL NQQ P E EE+ RP +K +NEKNKVK+QI+ +
Sbjct: 312 NLTDGAAAGNGDGGLVPQRKSRKHENQQFPNTEIEEYHRP-EKKSNEKNKVKSQIHSVDN 370
Query: 594 FADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKN 653
D PSEIASED +L S YE F LLIEQL+M++ DSASL +IQD EHLL+LKN
Sbjct: 371 LDDITWPSEIASEDYDLLFSNYETFTLLIEQLKMDFNDSASLSKIQDAVISEEHLLELKN 430
Query: 654 NHCDQLTVKLKQMENMVSVLQ 674
+H +QLTV+++QMENMV VLQ
Sbjct: 431 SHYEQLTVEVEQMENMVHVLQ 451
Score = 66.6 bits (161), Expect = 8e-11
Identities = 32/58 (55%), Positives = 42/58 (72%), Gaps = 1/58 (1%)
Query: 205 LHDLCQSQLPENKE-SKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDRE 261
L D ++Q+P N + EQDL+LTSEEE +RLKG EN Q +K +QEP++ KDCDRE
Sbjct: 237 LSDYKENQMPNNSSGNSNPEQDLKLTSEEEPQRLKGSENSQHEKVTQEPDINKDCDRE 294
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/104 (36%), Positives = 58/104 (55%), Gaps = 8/104 (7%)
Query: 12 AEGSPKLAVYATRKTRSVRSQEDQWYLG-YPGDQWSSGFSYSWWKNSVGSESKHGEGALD 70
AE SPKLA +K R + +W +P + S KN++G+ H + A
Sbjct: 3 AEVSPKLAASPMKKPFGFRGKMGKWCCCCFPCCRGSG-------KNNMGAWRDHDDSAFT 55
Query: 71 QPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
+P++ VR EDLG+LHRAA G+VP + ++ G++KRD+KK
Sbjct: 56 EPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKK 99
Score = 41.6 bits (96), Expect = 0.003
Identities = 60/222 (27%), Positives = 86/222 (38%), Gaps = 32/222 (14%)
Query: 111 DRKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPS 170
DR I QL+ +YKE Q P + N+NP+ LT S+E QR K + + V+
Sbjct: 228 DRFGRICQLLSDYKENQMPNNSSGNSNPE-QDLKLT-SEEEPQRLKGSE-NSQHEKVTQE 284
Query: 171 MPENQSATKEL-------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAE 223
N+ +E+ G N+ E + G +G+ L +P+ K K
Sbjct: 285 PDINKDCDREVEEEMQKHGSNNVGLSENLTDGAAAGNGDGGL-------VPQRKSRKHEN 337
Query: 224 QDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQG 283
Q T EE R P+K S E K I L + E+ E
Sbjct: 338 QQFPNTEIEEYHR--------PEKKSNEKNKVK----SQIHSVDNLDDITWPSEIASEDY 385
Query: 284 KLEWKN--QLKLVINELKQRFGEIYEKYKI-PACPEEEPLLD 322
L + N L+I +LK F + KI A EE LL+
Sbjct: 386 DLLFSNYETFTLLIEQLKMDFNDSASLSKIQDAVISEEHLLE 427
>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
sapiens]
Length = 498
Score = 166 bits (421), Expect = 5e-41
Identities = 105/233 (45%), Positives = 135/233 (57%), Gaps = 33/233 (14%)
Query: 452 KNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEE 511
+N N+ SG++N + LK TSE ++ Q+ K N+ E
Sbjct: 288 ENQMPNNSSGNSNPEQDLK--------------LTSE--------EEPQRLKGSENSQHE 325
Query: 512 EFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGL----------NQQ 561
+ N +EVEEEM+KH SN+ LS LTDG GN D GL NQQ
Sbjct: 326 KVTQEPDINKDCDREVEEEMQKHGSNNVGLSENLTDGAAAGNGDGGLVPQRKSRKHENQQ 385
Query: 562 IPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLL 621
P E EE+ RP +K +NEKNKVK+QI+ + D PSEIASED +L S YE F LL
Sbjct: 386 FPNTEIEEYHRP-EKKSNEKNKVKSQIHSVDNLDDITWPSEIASEDYDLLFSNYETFTLL 444
Query: 622 IEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQ 674
IEQL+M++ DSASL +IQD EHLL+LKN+H +QLTV+++QMENMV VLQ
Sbjct: 445 IEQLKMDFNDSASLSKIQDAVISEEHLLELKNSHYEQLTVEVEQMENMVHVLQ 497
Score = 66.6 bits (161), Expect = 8e-11
Identities = 32/58 (55%), Positives = 42/58 (72%), Gaps = 1/58 (1%)
Query: 205 LHDLCQSQLPENKE-SKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDRE 261
L D ++Q+P N + EQDL+LTSEEE +RLKG EN Q +K +QEP++ KDCDRE
Sbjct: 283 LSDYKENQMPNNSSGNSNPEQDLKLTSEEEPQRLKGSENSQHEKVTQEPDINKDCDRE 340
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/104 (36%), Positives = 58/104 (55%), Gaps = 8/104 (7%)
Query: 12 AEGSPKLAVYATRKTRSVRSQEDQWYLG-YPGDQWSSGFSYSWWKNSVGSESKHGEGALD 70
AE SPKLA +K R + +W +P + S KN++G+ H + A
Sbjct: 3 AEVSPKLAASPMKKPFGFRGKMGKWCCCCFPCCRGSG-------KNNMGAWRDHDDSAFT 55
Query: 71 QPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
+P++ VR EDLG+LHRAA G+VP + ++ G++KRD+KK
Sbjct: 56 EPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKK 99
Score = 39.7 bits (91), Expect = 0.010
Identities = 58/217 (26%), Positives = 84/217 (38%), Gaps = 32/217 (14%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPENQ 175
I QL+ +YKE Q P + N+NP+ LT S+E QR K + + V+ N+
Sbjct: 279 ICQLLSDYKENQMPNNSSGNSNPE-QDLKLT-SEEEPQRLKGSE-NSQHEKVTQEPDINK 335
Query: 176 SATKEL-------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDLEL 228
+E+ G N+ E + G +G+ L +P+ K K Q
Sbjct: 336 DCDREVEEEMQKHGSNNVGLSENLTDGAAAGNGDGGL-------VPQRKSRKHENQQFPN 388
Query: 229 TSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWK 288
T EE R P+K S E K I L + E+ E L +
Sbjct: 389 TEIEEYHR--------PEKKSNEKNKVK----SQIHSVDNLDDITWPSEIASEDYDLLFS 436
Query: 289 N--QLKLVINELKQRFGEIYEKYKI-PACPEEEPLLD 322
N L+I +LK F + KI A EE LL+
Sbjct: 437 NYETFTLLIEQLKMDFNDSASLSKIQDAVISEEHLLE 473
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 134 bits (338), Expect = 2e-31
Identities = 92/229 (40%), Positives = 128/229 (55%), Gaps = 20/229 (8%)
Query: 500 QKFKNEVNTLEEEFLALKKENVQLHKE--------VEEEMEKHRSNSTELSGTL--TDGT 549
++ K+ N+ E+ L + E Q E VEE+M+K R+ E+S + D
Sbjct: 263 KRCKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSD 322
Query: 550 TVGNDDDGL----------NQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSME 599
+D D L N Q P KEN E DR A KT+NEK+KVK+QIY D D
Sbjct: 323 NYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISG 382
Query: 600 PSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQL 659
SE SED EL +S ENFMLLIEQ ME KD SL + ++ C ++ + +C++L
Sbjct: 383 SSEKTSEDDELPYSDDENFMLLIEQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERL 442
Query: 660 TVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQE 708
VK ++M+N +SVLQ LSET KTK Q E Q ++ +K+L +LR L+Q+
Sbjct: 443 KVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQ 491
Score = 53.1 bits (126), Expect = 9e-07
Identities = 101/494 (20%), Positives = 196/494 (39%), Gaps = 76/494 (15%)
Query: 218 ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
++ +EQDLE+TSE EQERL+GCE+ QP Q E K C + + + + H S+
Sbjct: 269 QNSNSEQDLEMTSEGEQERLEGCESSQP----QVEEKMKKCRNKKMEVSRNV-HADDSD- 322
Query: 278 MWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPF-- 335
+ + + +I+++K R + ++ + S + VK +
Sbjct: 323 --------NYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFT 374
Query: 336 NLTNNIPG----CEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSS 391
+ N+I G E+D S F EQ K+ + S S+ ++
Sbjct: 375 DDLNDISGSSEKTSEDDELPYSDDENFMLLIEQSGMECKDFV-------SLSKSKNATAA 427
Query: 392 SKLHLHENKLDCD---------NDNKLGIGHIFS------TDNNFHNDASTKKARNPEVV 436
+ + K C+ +N + + S + + N KK N +
Sbjct: 428 CGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFI 487
Query: 437 TVEMKEDQ-------EFDLQMTKNMNQ------NSDSGSTNNYKSLKPKLENLSSLPPDS 483
+ +E++ E D++ K M + S KSL+ +L+ + S +
Sbjct: 488 LQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQN 547
Query: 484 DRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSG 543
T E +L Q+ ++E+ L E +K +N + + +++E + N+ +L
Sbjct: 548 FHTHE--RERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEK 605
Query: 544 TLTDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEI 603
TL +++ L + I R + + + +E + +++ E +E +E+
Sbjct: 606 TLK------RNEEALTKTITR-----YSKELNVLMDENTMLNSELQKEKQSMSRLE-TEM 653
Query: 604 ASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKL 663
S C L+ ++ ++ R K L Q T HL + N+H L+ +L
Sbjct: 654 ESYRCRLAAALCDH------DQRQSSKRDLQL-AFQSTVNEWCHLQEDTNSHIQILSQQL 706
Query: 664 KQMENMVSVLQNEL 677
+ E+ S L+ EL
Sbjct: 707 SKAESTSSGLETEL 720
Score = 30.8 bits (68), Expect = 4.6
Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 52 SWWKNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRD 111
+W KN + P + VR +DLG +H+AA +GDV V + ++ RD
Sbjct: 17 TWRKN-------RDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRD 69
Query: 112 RK 113
+K
Sbjct: 70 KK 71
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 132 bits (333), Expect = 9e-31
Identities = 84/195 (43%), Positives = 116/195 (59%), Gaps = 12/195 (6%)
Query: 526 EVEEEMEKHRSNSTELSGTL--TDGTTVGNDDDGL----------NQQIPRKENEEHDRP 573
+VEE+M+K R+ E+S + D +D D L N Q P KEN E DR
Sbjct: 297 QVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRL 356
Query: 574 ADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSA 633
A KT+NEK+KVK+QIY D D SE SED EL +S ENFMLLI+Q ME KD
Sbjct: 357 ARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFV 416
Query: 634 SLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIE 693
SL + ++ C ++ + +C++L VK ++M+N +SVLQ LSET KTK Q E Q ++
Sbjct: 417 SLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQ 476
Query: 694 WEKELYDLRLALKQE 708
+K+L +LR L+Q+
Sbjct: 477 GKKKLCNLRFILQQQ 491
Score = 49.7 bits (117), Expect = 1e-05
Identities = 99/492 (20%), Positives = 198/492 (40%), Gaps = 72/492 (14%)
Query: 218 ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
++ +EQDLE+TSE EQERL+GCE+ QP Q E K C + + + + H S+
Sbjct: 269 QNSNSEQDLEMTSEGEQERLEGCESSQP----QVEEKMKKCRNKKMEVSRNV-HADDSD- 322
Query: 278 MWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPF-- 335
+ + + +I+++K R + ++ + S + VK +
Sbjct: 323 --------NYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFT 374
Query: 336 NLTNNIPG----CEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSS 391
+ N+I G E+D S F +Q K+ + S S+ ++
Sbjct: 375 DDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFV-------SLSKSKNATAA 427
Query: 392 SKLHLHENKLDCDN--------DNKLGIGH--IFSTD-----NNFHNDASTKKARNPEVV 436
+ + K C+ N + + + TD + N KK N +
Sbjct: 428 CGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFI 487
Query: 437 TVEMKEDQ-------EFDLQMTKNMNQNSDSGSTNNYKS---LKPKLENLSSLPPDSDRT 486
+ +E++ E D++ K M + + + +S LK L ++ +S++
Sbjct: 488 LQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQN 547
Query: 487 SEVYLHE-ELQQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTL 545
+ E +L Q+ ++E+ L E +K +N + + +++E + N+ +L TL
Sbjct: 548 FHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTL 607
Query: 546 TDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
+++ L + I R + + + +E + +++ E +E +E+ S
Sbjct: 608 K------RNEETLTKTITR-----YSKELNVLMDENTMLNSELQKEKQSMSRLE-TEMES 655
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQ 665
C L+ ++ ++ R K L Q T HL + N+H L+ +L +
Sbjct: 656 YRCRLAAALCDH------DQRQSSKRDLQL-AFQSTVNEWCHLQEDTNSHIQILSQQLSK 708
Query: 666 MENMVSVLQNEL 677
E+ S L+ EL
Sbjct: 709 AESTSSGLETEL 720
Score = 30.8 bits (68), Expect = 4.6
Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 52 SWWKNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRD 111
+W KN + P + VR +DLG +H+AA +GDV V + ++ RD
Sbjct: 17 TWRKN-------RDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRD 69
Query: 112 RK 113
+K
Sbjct: 70 KK 71
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 132 bits (333), Expect = 9e-31
Identities = 84/195 (43%), Positives = 116/195 (59%), Gaps = 12/195 (6%)
Query: 526 EVEEEMEKHRSNSTELSGTL--TDGTTVGNDDDGL----------NQQIPRKENEEHDRP 573
+VEE+M+K R+ E+S + D +D D L N Q P KEN E DR
Sbjct: 297 QVEEKMKKCRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRL 356
Query: 574 ADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSA 633
A KT+NEK+KVK+QIY D D SE SED EL +S ENFMLLI+Q ME KD
Sbjct: 357 ARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFV 416
Query: 634 SLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIE 693
SL + ++ C ++ + +C++L VK ++M+N +SVLQ LSET KTK Q E Q ++
Sbjct: 417 SLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQ 476
Query: 694 WEKELYDLRLALKQE 708
+K+L +LR L+Q+
Sbjct: 477 GKKKLCNLRFILQQQ 491
Score = 49.7 bits (117), Expect = 1e-05
Identities = 99/492 (20%), Positives = 198/492 (40%), Gaps = 72/492 (14%)
Query: 218 ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
++ +EQDLE+TSE EQERL+GCE+ QP Q E K C + + + + H S+
Sbjct: 269 QNSNSEQDLEMTSEGEQERLEGCESSQP----QVEEKMKKCRNKKMEVSRNV-HADDSD- 322
Query: 278 MWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIPF-- 335
+ + + +I+++K R + ++ + S + VK +
Sbjct: 323 --------NYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFT 374
Query: 336 NLTNNIPG----CEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSS 391
+ N+I G E+D S F +Q K+ + S S+ ++
Sbjct: 375 DDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFV-------SLSKSKNATAA 427
Query: 392 SKLHLHENKLDCDN--------DNKLGIGH--IFSTD-----NNFHNDASTKKARNPEVV 436
+ + K C+ N + + + TD + N KK N +
Sbjct: 428 CGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFI 487
Query: 437 TVEMKEDQ-------EFDLQMTKNMNQNSDSGSTNNYKS---LKPKLENLSSLPPDSDRT 486
+ +E++ E D++ K M + + + +S LK L ++ +S++
Sbjct: 488 LQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQN 547
Query: 487 SEVYLHE-ELQQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTL 545
+ E +L Q+ ++E+ L E +K +N + + +++E + N+ +L TL
Sbjct: 548 FHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTL 607
Query: 546 TDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
+++ L + I R + + + +E + +++ E +E +E+ S
Sbjct: 608 K------RNEETLTKTITR-----YSKELNVLMDENTMLNSELQKEKQSMSRLE-TEMES 655
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQ 665
C L+ ++ ++ R K L Q T HL + N+H L+ +L +
Sbjct: 656 YRCRLAAALCDH------DQRQSSKRDLQL-AFQSTVNEWCHLQEDTNSHIQILSQQLSK 708
Query: 666 MENMVSVLQNEL 677
E+ S L+ EL
Sbjct: 709 AESTSSGLETEL 720
Score = 30.8 bits (68), Expect = 4.6
Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 52 SWWKNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRD 111
+W KN + P + VR +DLG +H+AA +GDV V + ++ RD
Sbjct: 17 TWRKN-------RDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRD 69
Query: 112 RK 113
+K
Sbjct: 70 KK 71
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 118 bits (295), Expect = 2e-26
Identities = 146/669 (21%), Positives = 281/669 (42%), Gaps = 93/669 (13%)
Query: 111 DRKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPS 170
D + S+ + E K+ + ++ P T D + +K G+KS +VS
Sbjct: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATT-DEKDSVSNIATEIKDGEKSGTVSSQ 471
Query: 171 MPENQSATK-ELGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEA------- 222
P +AT E G + RE D + T+ + L + K++
Sbjct: 472 KPPALTATSDEEGSVLSIARENKDG-----EKSRTVSSRKKPALKATSDEKDSFSNITRG 526
Query: 223 EQDLELT---SEEEQERLKGCENKQPQ-----KTSQEPEMAKDCDREDIPIYPVLPHVQK 274
++D E++ S ++ LKG +++ + +++ E ++ E P +K
Sbjct: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA-SSAEK 585
Query: 275 SEEMWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIP 334
+ I +GK + + ++ + K + A +E+ N TR +I
Sbjct: 586 DSVLNIARGKKDGEKTKRVSSRK----------KPSLEATSDEKDSFSNITREKKDGEIS 635
Query: 335 FNLTNNIP----GCEEEDASEISVS------VVFETFPEQKEPSLK-------NIIHPYY 377
+++ P G +E+ S + ++ T +K P LK ++++
Sbjct: 636 RKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIAR 695
Query: 378 HPYSGSQEHVCQSSSKLHLHENKLDCDNDNKLGIGHIFSTDNNFHNDASTKKARNPEVVT 437
G + S + L K CD ++ + D S +K P +
Sbjct: 696 GKKDGEKTRTVSSPKQPAL---KAICDKEDSVPNMATEKKDEQISGTVSCQK--QPALKA 750
Query: 438 VEMKEDQEFDLQMTKNMNQNSDSGSTNN---YKSLKPKLENLSSLPPDSDRTSEVYLHEE 494
K+D ++ Q S + S+ +K+ K +++S++ + + ++
Sbjct: 751 TSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEI-KDGQIRGTGI 809
Query: 495 LQQDMQKFKNEVNTLEEEFLALKK------ENVQLHKEVEEEMEKHRSNSTELSGTLTDG 548
L+ F + +EE+F +L K + K + ++ + +T ++G G
Sbjct: 810 LEYT---FNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSG 866
Query: 549 T-----------TVGNDDDGLNQQIPRKE--------------NEEHDRPADKTANEKNK 583
T T+ N + LN K+ +E + ++ N + +
Sbjct: 867 TEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQ 926
Query: 584 VKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFC 643
VKNQI+ D D ++ S+ SED + +N +LLI+Q M+ KD L +I++TFC
Sbjct: 927 VKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFC 986
Query: 644 LCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRL 703
L + L+KLK+NHC+QL VK+++++N SVLQ +SE ++ K QL+ + +E EKEL LR
Sbjct: 987 LWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRF 1046
Query: 704 ALKQENGRK 712
A++QE ++
Sbjct: 1047 AIQQEKKKR 1055
Score = 33.5 bits (75), Expect = 0.71
Identities = 55/260 (21%), Positives = 107/260 (41%), Gaps = 39/260 (15%)
Query: 428 KKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTS 487
KK RN E V +++E L++T+ + + +LK L + +S++ S
Sbjct: 1053 KKRRNVEEVHQKVREK----LRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVS 1108
Query: 488 EVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLH--KEVEEEMEKHRSNSTELSGTL 545
E E+L + + ++E+ L E +K +N++ K+ E KH L
Sbjct: 1109 ETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK--- 1165
Query: 546 TDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
+G T+ + Q+ +E +++++ + + +E +E+ S
Sbjct: 1166 RNGETLAKTIACYSGQLAA------------LTDENTTLRSKLEKQRESRQRLE-TEMQS 1212
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQD-----TFCLCEHLLKLKNNHCDQLT 660
C L+ + R ++ S S R Q+ T C HL + N+H L+
Sbjct: 1213 YHCRLNAA------------RCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILS 1260
Query: 661 VKLKQMENMVSVLQNELSET 680
++L + E+ VL+ EL T
Sbjct: 1261 LQLSKAESKSRVLKTELHYT 1280
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 117 bits (293), Expect = 4e-26
Identities = 151/696 (21%), Positives = 286/696 (41%), Gaps = 105/696 (15%)
Query: 111 DRKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPS 170
D K S+ + E KE ++ P T+ D + +K G +S +VSP
Sbjct: 277 DDKDSVSNIATEIKEGPISGTVSSQKQPAEKATS-DEKDSVSNIATEIKEGQQSGTVSP- 334
Query: 171 MPENQSATKEL-----------------GQMNLTEREKMDTGVVLLSGNDTLHDLC---Q 210
+ QSA K + G+ +K D+ ++ +
Sbjct: 335 --QKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIK 392
Query: 211 SQLPENKESKEAEQDLELTSEEEQE------RLKGCENKQPQKTSQEPEMAKDCDRED-- 262
L S + + L+ T++EE +K E + ++P + D ED
Sbjct: 393 DGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSV 452
Query: 263 IPIYPVLPHVQKSEEMWIEQ-----GKLEWKNQLKLVINELK--QRFGEIYEKYK--IPA 313
+ I + +KSE + ++ + ++ + ++ E+K ++ G + + K + A
Sbjct: 453 LNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKA 512
Query: 314 CPEEEPLLDNSTRGTDVKDIPFNLTNNIPGC-----EEED-----ASEISVSVVFETFPE 363
+E+ N TR +I +++ P +EED A E T
Sbjct: 513 TSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSS 572
Query: 364 QKEPSLK-------NIIHPYYHPYSGSQEHVCQSSSKLHLHENKLDCDNDNKLGIGHIFS 416
++ P LK ++++ G + S + L K D +N + +
Sbjct: 573 EQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPAL---KATSDKENSVPNMATET 629
Query: 417 TDNNFHNDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNN---YKSLKPKL 473
D S++K P + K+D ++ Q S + S+ +K+ K
Sbjct: 630 KDEQISGTVSSQK--QPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKK 687
Query: 474 ENLSSLPPD-----------SDRTSEVYLHEELQQDMQKFKNEVNTLEEE-FLALKKENV 521
+++S++ + S R + + + + E+ E+ ++ +K++
Sbjct: 688 DSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSA 747
Query: 522 QLHKEVEEEMEKHRSNSTELSGTLTDGT-----------TVGNDDDGLNQQIPRKE---- 566
Q K + ++ + +T ++G GT T+ N + LN K+
Sbjct: 748 Q--KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 805
Query: 567 ----------NEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYE 616
+E + ++ N + +VKNQI+ D D ++ S+ SED + +
Sbjct: 806 TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCK 865
Query: 617 NFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNE 676
N +LLI+Q M+ KD L +I+ TFCLC+ L +LK+NHC+QL VK+++++N SVLQ
Sbjct: 866 NVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKR 925
Query: 677 LSETKKTKLQLELQKIEWEKELYDLRLALKQENGRK 712
LSE ++ K QL+ + +E EKEL LR A++QE ++
Sbjct: 926 LSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKR 961
Score = 43.5 bits (101), Expect = 7e-04
Identities = 116/592 (19%), Positives = 222/592 (37%), Gaps = 114/592 (19%)
Query: 112 RKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSM 171
+K S+ + E K+ Q ++ P T D ++ +K G+KS +VSP
Sbjct: 686 KKDSVSNIATEIKDGQIRGTVSSQRQPALKATG-DEKDSVSNIAREIKDGEKSGTVSPQK 744
Query: 172 PENQSAT--KELGQMNLTER------------EKMDTGVVLLSGNDTLHDLCQSQLPENK 217
Q K++ +N+ R E + T + +++ + +++ + +
Sbjct: 745 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTA-TKMKDVQ 803
Query: 218 ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
S AEQDLE+ SE EQ+RL+ E + Q + ++D D +DI +Q S+
Sbjct: 804 TSTPAEQDLEMASEGEQKRLE--EYENNQPQVKNQIHSRD-DLDDI--------IQSSQT 852
Query: 278 MWIEQGKL--EWKNQLKLVINELKQRFGEIYEKYKIPA----CPEEEPLLDNSTRGTDVK 331
+ + L KN + L+I++ + + + KI C L DN VK
Sbjct: 853 VSEDGDSLCCNCKNVI-LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVK 911
Query: 332 DIPFNLTNNIPGCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSS 391
++ + EI + ET +KE S Q
Sbjct: 912 IRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELC--------------SLRFAIQQE 957
Query: 392 SKLHLHENKLDCDNDNKLGIGHIFSTDNNFHNDASTKKARNPEVVTVEMKEDQEFDLQMT 451
K + +L KL I T+ + +A K P + + E++
Sbjct: 958 KKKRRNVEELHQKVREKLRI-----TEEQYRIEADVTKPIKPALKSAEVE---------L 1003
Query: 452 KNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEE--LQQDMQKFKNEVNTL 509
K NS+ S + K E LHE +Q ++ + + E +T+
Sbjct: 1004 KTGGNNSNQVSETDEK--------------------EDLLHENRLMQDEIARLRLEKDTI 1043
Query: 510 EEEFLALKK-ENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQIPRKENE 568
+ + L K ++ ++ K E+++K + E TL +
Sbjct: 1044 KNQNLEKKYLKDFEIVKRKHEDLQKALKRNEE---TLAETIAC----------------- 1083
Query: 569 EHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRME 628
+ +E +++++ + + +E +E+ S C L+ ++ ++ +Q
Sbjct: 1084 -YSGQLAALTDENTTLRSKLEKQRESGQRLE-TEMQSYRCRLNAALCDH-----DQSHSS 1136
Query: 629 YKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSET 680
+D Q T C HL + N+H L+++L + E+ VL+ EL T
Sbjct: 1137 KRDQELA--FQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYT 1186
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 115 bits (288), Expect = 1e-25
Identities = 69/194 (35%), Positives = 111/194 (57%), Gaps = 9/194 (4%)
Query: 519 ENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQIPRKENEEHDRPADKTA 578
EN+ K E + +T++ T +T D + + +K EE++
Sbjct: 215 ENLPTLKATIENKNSVLNTATKMKDVQT--STPAEQDLEMASEGEQKRLEEYE------- 265
Query: 579 NEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRI 638
N + +VKNQI+ D D ++ S+ SED + +N +LLI+Q M+ KD L +I
Sbjct: 266 NNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKI 325
Query: 639 QDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKEL 698
+ TFCLC+ L +LK+NHC+QL VK+++++N SVLQ LSE ++ K QL+ + +E EKEL
Sbjct: 326 KKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKEL 385
Query: 699 YDLRLALKQENGRK 712
LR A++QE ++
Sbjct: 386 CSLRFAIQQEKKKR 399
Score = 57.0 bits (136), Expect = 6e-08
Identities = 97/460 (21%), Positives = 178/460 (38%), Gaps = 59/460 (12%)
Query: 112 RKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSM 171
+K S+ + E K+ Q ++ P T D ++ +K G+KS +VSP
Sbjct: 124 KKDSVSNIATEIKDGQIRGTVSSQRQPALKATG-DEKDSVSNIAREIKDGEKSGTVSPQK 182
Query: 172 PENQSAT--KELGQMNLTER------------EKMDTGVVLLSGNDTLHDLCQSQLPENK 217
Q K++ +N+ R E + T + +++ + +++ + +
Sbjct: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTA-TKMKDVQ 241
Query: 218 ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
S AEQDLE+ SE EQ+RL+ EN QPQ +Q + D +DI +Q S+
Sbjct: 242 TSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ---IHSRDDLDDI--------IQSSQT 290
Query: 278 MWIEQGKL--EWKNQLKLVINELKQRFGEIYEKYKIP----ACPEEEPLLDNSTRGTDVK 331
+ + L KN + L+I++ + + + KI C L DN VK
Sbjct: 291 VSEDGDSLCCNCKNVI-LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVK 349
Query: 332 DIPFNLTNNIPGCEEEDASEISVSVVFETFPEQKE-PSLKNIIHPYYHPYSGSQEHVCQS 390
++ + EI + ET +KE SL+ I +E +
Sbjct: 350 IRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKV 409
Query: 391 SSKLHLHENKLDCDNDNKLGIGHI-------FSTDNNFHNDASTKKARNPEVVTVEMKED 443
KL + E + + D I T N N S + + + +D
Sbjct: 410 REKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQD 469
Query: 444 QEFDLQMTKN--MNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQK 501
+ L++ K+ NQN + +++ +K K E+ L + L+++ +
Sbjct: 470 EIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHED---------------LQKALKRNEET 514
Query: 502 FKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTEL 541
+ + AL EN L ++E++ E + TE+
Sbjct: 515 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEM 554
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 114 bits (285), Expect = 3e-25
Identities = 68/194 (35%), Positives = 114/194 (58%), Gaps = 9/194 (4%)
Query: 519 ENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQIPRKENEEHDRPADKTA 578
EN++ K E + + +T++ T +T D + + +K EE++
Sbjct: 468 ENLRTLKATIENKDSVLNTATKMKEVQT--STPAEQDLEMASEGEQKRLEEYE------- 518
Query: 579 NEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRI 638
N + +VKNQI+ D D ++ S+ SED + +N +LLI+Q M+ KD L +I
Sbjct: 519 NNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKI 578
Query: 639 QDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKEL 698
++TFCL + L+KLK+NHC+QL VK+++++N SVLQ +SE ++ K QL+ + +E EKEL
Sbjct: 579 KNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKEL 638
Query: 699 YDLRLALKQENGRK 712
LR A++QE ++
Sbjct: 639 CSLRFAIQQEKKKR 652
Score = 54.7 bits (130), Expect = 3e-07
Identities = 99/459 (21%), Positives = 177/459 (38%), Gaps = 57/459 (12%)
Query: 112 RKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSM 171
+K S+ + E K+ Q ++ P T D ++ +K G+KS +VSP
Sbjct: 377 KKDSVSNIATEIKDGQIRGTVSSQRRPALKTTG-DEKDSVSNIAREIKDGEKSGTVSPQK 435
Query: 172 PENQSAT--KELGQMNLTER------------EKMDTGVVLLSGNDTLHDLCQSQLPENK 217
Q K++ +N+ R E + T + D++ + +++ E +
Sbjct: 436 QSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTA-TKMKEVQ 494
Query: 218 ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
S AEQDLE+ SE EQ+RL+ EN QPQ +Q + D +DI +Q S+
Sbjct: 495 TSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ---IHSRDDLDDI--------IQSSQT 543
Query: 278 MWIEQGKL--EWKNQLKLV-INELKQRFGEIYEKYKIPACPEEE--PLLDNSTRGTDVKD 332
+ + L KN + L+ +E+K + K K C + L DN VK
Sbjct: 544 VSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKI 603
Query: 333 IPFNLTNNIPGCEEEDASEISVSVVFETFPEQKE-PSLKNIIHPYYHPYSGSQEHVCQSS 391
++ + EI + E +KE SL+ I +E +
Sbjct: 604 RKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVR 663
Query: 392 SKLHLHENKLDCDNDNKLGIGHI-------FSTDNNFHNDASTKKARNPEVVTVEMKEDQ 444
KL + E + + D I T N N S + + + +D+
Sbjct: 664 EKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDE 723
Query: 445 EFDLQMTKN--MNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKF 502
L++ K+ NQN + +++ +K K E+ L + L+++ +
Sbjct: 724 IARLRLEKDTIKNQNLEKKYLKDFEIVKRKHED---------------LQKALKRNGETL 768
Query: 503 KNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTEL 541
+ + AL EN L ++E++ E + TE+
Sbjct: 769 AKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEM 807
Score = 32.0 bits (71), Expect = 2.1
Identities = 54/260 (20%), Positives = 107/260 (41%), Gaps = 39/260 (15%)
Query: 428 KKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTS 487
KK RN E + +++E L++T+ + + +LK L + +S++ S
Sbjct: 650 KKRRNVEELHQKVREK----LRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVS 705
Query: 488 EVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLH--KEVEEEMEKHRSNSTELSGTL 545
E E+L + + ++E+ L E +K +N++ K+ E KH L
Sbjct: 706 ETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK--- 762
Query: 546 TDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
+G T+ + Q+ +E +++++ + + +E +E+ S
Sbjct: 763 RNGETLAKTIACYSGQLAA------------LTDENTTLRSKLEKQRESRQRLE-TEMQS 809
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQD-----TFCLCEHLLKLKNNHCDQLT 660
C L+ + R ++ S S R Q+ T C HL + N+H L+
Sbjct: 810 YRCRLNAA------------RCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILS 857
Query: 661 VKLKQMENMVSVLQNELSET 680
++L + E+ VL+ EL T
Sbjct: 858 LQLSKAESKSRVLKTELHYT 877
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 81.3 bits (199), Expect = 3e-15
Identities = 38/82 (46%), Positives = 60/82 (73%)
Query: 631 DSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQ 690
D L +I++TFCL + L+KLK+NHC+QL VK+++++N SVLQ +SE ++ K QL+ +
Sbjct: 24 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 83
Query: 691 KIEWEKELYDLRLALKQENGRK 712
+E EKEL LR A++QE ++
Sbjct: 84 ILELEKELCSLRFAIQQEKKKR 105
Score = 31.6 bits (70), Expect = 2.7
Identities = 53/260 (20%), Positives = 107/260 (41%), Gaps = 39/260 (15%)
Query: 428 KKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTS 487
KK RN E + +++E L++T+ + + +LK L + +S++ S
Sbjct: 103 KKRRNVEELHQKVREK----LRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVS 158
Query: 488 EVYLHEELQQDMQKFKNEVNTLEEEFLALKKENVQLH--KEVEEEMEKHRSNSTELSGTL 545
E E+L + + ++E+ L + +K +N++ K+ E KH L
Sbjct: 159 ETDEKEDLLHENRLMQDEIARLRLDTDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK--- 215
Query: 546 TDGTTVGNDDDGLNQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
+G T+ + Q+ +E +++++ + + +E +E+ S
Sbjct: 216 RNGETLAKTIACYSGQLAA------------LTDENTTLRSKLEKQRESRQRLE-TEMQS 262
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQD-----TFCLCEHLLKLKNNHCDQLT 660
C L+ + R ++ S S R Q+ T C HL + N+H L+
Sbjct: 263 YHCRLNAA------------RCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILS 310
Query: 661 VKLKQMENMVSVLQNELSET 680
++L + E+ VL+ EL T
Sbjct: 311 LQLSKAESKSRVLKTELHYT 330
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 80.5 bits (197), Expect = 5e-15
Identities = 71/242 (29%), Positives = 113/242 (46%), Gaps = 32/242 (13%)
Query: 497 QDMQKFKNE-VNTLEEEFLALKK---ENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVG 552
+D + FK E V+++E F K EN Q K VEE+ N T G T
Sbjct: 788 KDRETFKAEDVSSVESTFSLFGKPTTENSQSTK-VEEDF-----NLTTKEGATKTVTGQQ 841
Query: 553 NDDDGLNQQIPRKENE-----EHDRPADKTANEKNKVKN-------QIYPEADFADSMEP 600
D G+ ++ P+ + E R D + +++ + + PEA + ++
Sbjct: 842 ERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKT 901
Query: 601 SEIASEDCELSHSVYE---NFMLLIEQLRMEYK-------DSASLPRIQDTFCLCEHLLK 650
+ E+ S +E + +E+K DS +L +I D CE +
Sbjct: 902 TNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRE 961
Query: 651 LKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENG 710
LK ++C+Q+T K++Q +N VLQ ELSE K+ K QLE QK +WE+EL +RL L QE
Sbjct: 962 LKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEE 1021
Query: 711 RK 712
++
Sbjct: 1022 KR 1023
Score = 37.0 bits (84), Expect = 0.065
Identities = 79/389 (20%), Positives = 148/389 (38%), Gaps = 55/389 (14%)
Query: 178 TKELGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDLELTSEEEQERL 237
TKE +T +++ D G++ + D + + S+L KE ++ D E+ S + +
Sbjct: 829 TKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSEL-GRKEDTKSTSDSEIISVSDTQNY 887
Query: 238 KGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMW--IEQGKLEWKNQLKLVI 295
+ C P+ T Q+ + E+ P P H + + EM + LEWKN K +
Sbjct: 888 E-C---LPEATYQKEIKTTNGKIEESPEKP--SHFEPATEMQNSVPNKGLEWKN--KQTL 939
Query: 296 NELKQRFGEIYEKYKIPACPEEEPL-LDNSTRGT------------------DVKDIPFN 336
+I + +P+C L DN + T + K+I
Sbjct: 940 RADSTTLSKILD--ALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQ 997
Query: 337 LTNNIPGCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKLHL 396
L N E+E S + +++ E + LK I P E Q L +
Sbjct: 998 LENQKAKWEQELCS-VRLTLNQEEEKRRNVDILKEKIRP-EEQLRKKLEVKQQLEQTLRI 1055
Query: 397 HENKLDCDNDNKLGIGHIFSTDNN-FHNDASTKK---ARNPEVVTV----EMKEDQEF-- 446
+ +L N + H ++N+ FH + KK EV T+ ++KE++ F
Sbjct: 1056 QDIELKSVTSNLNQVSHTHESENDLFHENCMLKKEIAMLKLEVATLKHQHQVKENKYFED 1115
Query: 447 ---------DLQMTKNMNQNSDSGSTNNYKSLKPKL--ENLSSLPPDSDRTSEVYLHEEL 495
+LQMT + Q + + + Y+ L EN ++ + L E+
Sbjct: 1116 IKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDKEILETEI 1175
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLH 524
+ + + + ++ + K + + H
Sbjct: 1176 ESHHPRLASALQDHDQSVTSRKNQELAFH 1204
>gi|113413200 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 1038
Score = 79.7 bits (195), Expect = 9e-15
Identities = 64/184 (34%), Positives = 89/184 (48%), Gaps = 42/184 (22%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPE-N 174
I QL+ +YKEKQ + +N+NP+ LT S+E QR K + + P PE N
Sbjct: 316 ICQLLSDYKEKQMLKISSENSNPE-QDLKLT-SEEESQRFKGSE--NSQPEKMSQEPEIN 371
Query: 175 QSATKELGQM-------NLTEREKMDTGVVLLSGNDTLHDLCQSQLPENK---------- 217
+ +E+ + N+ E + GV +G+D L +S+ PEN+
Sbjct: 372 KDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEY 431
Query: 218 --------------------ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKD 257
E+ EQDL+LTSEEE +RLKG EN QP+K SQEPE+ KD
Sbjct: 432 HRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKD 491
Query: 258 CDRE 261
DRE
Sbjct: 492 GDRE 495
Score = 63.9 bits (154), Expect = 5e-10
Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 10/98 (10%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+FK N+ E+ + N +EVEEEM+KH SN+ L L++G T GN D
Sbjct: 347 EEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGD 406
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNK 583
DGL NQQ P E+EE+ R + ++ K K
Sbjct: 407 DGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEK 444
Score = 52.4 bits (124), Expect = 1e-06
Identities = 98/403 (24%), Positives = 158/403 (39%), Gaps = 96/403 (23%)
Query: 353 SVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEH--VCQSSSK------LHLHENKLDCD 404
S S+V + + S +++ Y+ S H +CQ S L + + +
Sbjct: 280 SASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPE 339
Query: 405 NDNKLGIGHIFSTDNNFHNDASTKKARNPEV-------VTVEMKEDQEFDLQMTKNMNQ- 456
D KL N K ++ PE+ V EMK+ + ++ + +N++
Sbjct: 340 QDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNG 399
Query: 457 ----NSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVY------LHEELQQDMQKFKNEV 506
N D G KS P+ + PD++ SE Y + + ++ M K+ +E
Sbjct: 400 VTAGNGDDGLIPQRKSRTPENQQF----PDNE--SEEYHRICELVSDYKEKQMPKYSSEN 453
Query: 507 N--------TLEEEFLALK-KENVQLHKEVEE------------------EMEKHRSNST 539
+ T EEE LK EN Q K +E EM+KH S
Sbjct: 454 SNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHV 513
Query: 540 ELSGTLTDGTTVGNDDDGL----------NQQIPRKENEE-HDRPADKTANEKNKVKNQ- 587
LT+G T GN DDGL +QQ P ENEE H + T + + +N
Sbjct: 514 GFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTG 573
Query: 588 -IYPEADFADSMEPSEIASEDCELSHS-------VYENFMLL--IEQLRMEYKDSASLPR 637
++ E + + + + ELS S ++EN ML I LR+E
Sbjct: 574 ILHDEILIHEEKQIEVVEKMNSELSLSCKKERDFLHENSMLREEIAMLRLEL-------- 625
Query: 638 IQDTFCLCEHLLKL-KNNHCDQLTVKLKQMENMVSVLQ-NELS 678
DT +H +L K + + + K+ +N++ LQ NEL+
Sbjct: 626 --DTM---KHQSQLRKKKYLEDIESVKKKNDNLLKALQLNELT 663
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/60 (38%), Positives = 39/60 (65%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K++VG+ + + A +P++ VR EDL +LHRAA G V + ++ DT V+K+D++K
Sbjct: 77 KSNVGAWGDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQK 136
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPE-N 174
I +LV +YKEKQ P+ +N+NP+ LT S+E QR K + G P PE N
Sbjct: 434 ICELVSDYKEKQMPKYSSENSNPE-QDLKLT-SEEESQRLKGSENGQ--PEKRSQEPEIN 489
Query: 175 QSATKEL------------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEA 222
+ +EL G ++ E + G +G+D L +S+ PE+++ +
Sbjct: 490 KDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDT 549
Query: 223 EQDLELTSEEEQERLKGCENK 243
E + + E+ + + CE +
Sbjct: 550 ENEEYHSDEQNDTQKQFCEEQ 570
>gi|88953571 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
Length = 1075
Score = 79.7 bits (195), Expect = 9e-15
Identities = 64/184 (34%), Positives = 89/184 (48%), Gaps = 42/184 (22%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPE-N 174
I QL+ +YKEKQ + +N+NP+ LT S+E QR K + + P PE N
Sbjct: 353 ICQLLSDYKEKQMLKISSENSNPE-QDLKLT-SEEESQRFKGSE--NSQPEKMSQEPEIN 408
Query: 175 QSATKELGQM-------NLTEREKMDTGVVLLSGNDTLHDLCQSQLPENK---------- 217
+ +E+ + N+ E + GV +G+D L +S+ PEN+
Sbjct: 409 KDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEY 468
Query: 218 --------------------ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKD 257
E+ EQDL+LTSEEE +RLKG EN QP+K SQEPE+ KD
Sbjct: 469 HRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKD 528
Query: 258 CDRE 261
DRE
Sbjct: 529 GDRE 532
Score = 63.9 bits (154), Expect = 5e-10
Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 10/98 (10%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+FK N+ E+ + N +EVEEEM+KH SN+ L L++G T GN D
Sbjct: 384 EEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGD 443
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNK 583
DGL NQQ P E+EE+ R + ++ K K
Sbjct: 444 DGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEK 481
Score = 52.0 bits (123), Expect = 2e-06
Identities = 94/394 (23%), Positives = 155/394 (39%), Gaps = 78/394 (19%)
Query: 353 SVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEH--VCQSSSK------LHLHENKLDCD 404
S S+V + + S +++ Y+ S H +CQ S L + + +
Sbjct: 317 SASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPE 376
Query: 405 NDNKLGIGHIFSTDNNFHNDASTKKARNPEV-------VTVEMKEDQEFDLQMTKNMNQ- 456
D KL N K ++ PE+ V EMK+ + ++ + +N++
Sbjct: 377 QDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNG 436
Query: 457 ----NSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVY------LHEELQQDMQKFKNEV 506
N D G KS P+ + PD++ SE Y + + ++ M K+ +E
Sbjct: 437 VTAGNGDDGLIPQRKSRTPENQQF----PDNE--SEEYHRICELVSDYKEKQMPKYSSEN 490
Query: 507 N--------TLEEEFLALK-KENVQLHKEVEE------------------EMEKHRSNST 539
+ T EEE LK EN Q K +E EM+KH S
Sbjct: 491 SNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHV 550
Query: 540 ELSGTLTDGTTVGNDDDGL----------NQQIPRKENEE-HDRPADKTANEKNKVKNQ- 587
LT+G T GN DDGL +QQ P ENEE H + T + + +N
Sbjct: 551 GFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTG 610
Query: 588 -IYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCE 646
++ E + + + + ELS S + L E + ++ A L DT +
Sbjct: 611 ILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDFLHENSTLR-EEIAMLRLELDTM---K 666
Query: 647 HLLKL-KNNHCDQLTVKLKQMENMVSVLQ-NELS 678
H +L K + + + K+ +N++ LQ NEL+
Sbjct: 667 HQSQLRKKKYLEDIESVKKKNDNLLKALQLNELT 700
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/60 (38%), Positives = 39/60 (65%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K++VG+ + + A +P++ VR EDL +LHRAA G V + ++ DT V+K+D++K
Sbjct: 114 KSNVGAWGDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQK 173
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPE-N 174
I +LV +YKEKQ P+ +N+NP+ LT S+E QR K + G P PE N
Sbjct: 471 ICELVSDYKEKQMPKYSSENSNPE-QDLKLT-SEEESQRLKGSENGQ--PEKRSQEPEIN 526
Query: 175 QSATKEL------------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEA 222
+ +EL G ++ E + G +G+D L +S+ PE+++ +
Sbjct: 527 KDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDT 586
Query: 223 EQDLELTSEEEQERLKGCENK 243
E + + E+ + + CE +
Sbjct: 587 ENEEYHSDEQNDTQKQFCEEQ 607
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 79.3 bits (194), Expect = 1e-14
Identities = 47/142 (33%), Positives = 80/142 (56%), Gaps = 10/142 (7%)
Query: 579 NEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLL--------IEQLRMEYK 630
NE+ +Q++P +E + SE L +V + + + ++++ + +
Sbjct: 843 NEQTLRADQMFPSESKQKKVEENSWDSES--LRETVSQKDVCVPKATHQKEMDKISGKLE 900
Query: 631 DSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQ 690
DS SL +I DT CE +L+ +HC+Q T K++QM+ VL+ +LSE K+ K QLE Q
Sbjct: 901 DSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQ 960
Query: 691 KIEWEKELYDLRLALKQENGRK 712
K++WE+EL +RL L QE ++
Sbjct: 961 KVKWEQELCSVRLTLNQEEEKR 982
>gi|134133226 protein expressed in prostate, ovary, testis, and
placenta 2 [Homo sapiens]
Length = 1075
Score = 77.4 bits (189), Expect = 4e-14
Identities = 61/183 (33%), Positives = 89/183 (48%), Gaps = 40/183 (21%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPENQ 175
I QL+ +YKEKQ + +N+NP+ LT S+E QR K + + +S + N+
Sbjct: 353 ICQLLSDYKEKQMLKISSENSNPE-QELKLT-SEEESQRFKGSE-NSQPEKMSQELEINK 409
Query: 176 SATKELGQM-------NLTEREKMDTGVVLLSGNDTLHDLCQSQLPENK----------- 217
+E+ + N+ E + GV +G++ L +S+ PEN+
Sbjct: 410 DGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYH 469
Query: 218 -------------------ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDC 258
E+ EQDL+LTSEEE +RLKG EN QP+K SQEPE+ KD
Sbjct: 470 RICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDG 529
Query: 259 DRE 261
DRE
Sbjct: 530 DRE 532
Score = 62.8 bits (151), Expect = 1e-09
Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 10/98 (10%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+FK N+ E+ + N +EVEEEM+KH SN+ L LT+G T GN D
Sbjct: 384 EEESQRFKGSENSQPEKMSQELEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGD 443
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNK 583
+GL NQQ P E+EE+ R + ++ K K
Sbjct: 444 NGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEK 481
Score = 57.8 bits (138), Expect = 4e-08
Identities = 31/64 (48%), Positives = 39/64 (60%), Gaps = 8/64 (12%)
Query: 206 HDLCQ--------SQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKD 257
H +CQ L + E+ EQ+L+LTSEEE +R KG EN QP+K SQE E+ KD
Sbjct: 351 HVICQLLSDYKEKQMLKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELEINKD 410
Query: 258 CDRE 261
DRE
Sbjct: 411 GDRE 414
Score = 50.1 bits (118), Expect = 7e-06
Identities = 73/294 (24%), Positives = 113/294 (38%), Gaps = 61/294 (20%)
Query: 346 EEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSKLHLHENKLDCDN 405
E++ S + +T E S ++I Y Q S + E KL +
Sbjct: 326 EQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQELKLTSEE 385
Query: 406 DNKLGIGHIFSTDNNFHNDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQ-----NSDS 460
+++ G S + K + EV EMK+ + ++ + +N+ N D+
Sbjct: 386 ESQRFKGSENSQPEKMSQELEINKDGDREVEE-EMKKHESNNVGLLENLTNGVTAGNGDN 444
Query: 461 GSTNNYKSLKPKLENLSSLPPDSDRTSEVY------LHEELQQDMQKFKNEVN------- 507
G KS P+ + PD++ SE Y L + ++ M K+ +E +
Sbjct: 445 GLIPQRKSRTPENQQF----PDNE--SEEYHRICELLSDYKEKQMPKYSSENSNPEQDLK 498
Query: 508 -TLEEEFLALK-KENVQLHKEVEE------------------EMEKHRSNSTELSGTLTD 547
T EEE LK EN Q K +E EM+KH S LT+
Sbjct: 499 LTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTN 558
Query: 548 GTTVGNDDDGL----------NQQIPRKENEEHDRPADKTANEKNKVKNQIYPE 591
G T GN DDGL +QQ P ENEE+ ++E+N + Q E
Sbjct: 559 GATAGNGDDGLIPPRKSRTPESQQFPDTENEEYH------SDEQNDTQKQFCEE 606
Score = 47.8 bits (112), Expect = 4e-05
Identities = 24/60 (40%), Positives = 39/60 (65%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K+ VG+ + + A +P++ VR EDL +LHRAA G VP + ++ DT V+K+D++K
Sbjct: 114 KSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQK 173
Score = 43.9 bits (102), Expect = 5e-04
Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPE-N 174
I +L+ +YKEKQ P+ +N+NP+ LT S+E QR K + G P PE N
Sbjct: 471 ICELLSDYKEKQMPKYSSENSNPE-QDLKLT-SEEESQRLKGSENG--QPEKRSQEPEIN 526
Query: 175 QSATKEL------------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEA 222
+ +EL G ++ E + G +G+D L +S+ PE+++ +
Sbjct: 527 KDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDT 586
Query: 223 EQDLELTSEEEQERLKGCENK 243
E + + E+ + + CE +
Sbjct: 587 ENEEYHSDEQNDTQKQFCEEQ 607
>gi|153791352 prostate, ovary, testis expressed protein on
chromosome 2 [Homo sapiens]
Length = 1075
Score = 77.4 bits (189), Expect = 4e-14
Identities = 63/184 (34%), Positives = 89/184 (48%), Gaps = 42/184 (22%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPE-N 174
I QL+ +YKEKQ + +N+NP+ LT S+E QR K + + P PE N
Sbjct: 353 ICQLLSDYKEKQMLKISSENSNPE-QDLKLT-SEEESQRFKGSE--NSQPEKMSQEPEIN 408
Query: 175 QSATKELGQM-------NLTEREKMDTGVVLLSGNDTLHDLCQSQLPENK---------- 217
+ +E+ + N+ E + GV +G++ L +S+ PEN+
Sbjct: 409 KDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEY 468
Query: 218 --------------------ESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKD 257
E+ EQDL+LTSEEE +RLKG EN QP+K SQEPE+ KD
Sbjct: 469 HRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKD 528
Query: 258 CDRE 261
DRE
Sbjct: 529 GDRE 532
Score = 63.2 bits (152), Expect = 8e-10
Identities = 33/64 (51%), Positives = 40/64 (62%), Gaps = 8/64 (12%)
Query: 206 HDLCQ--------SQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKD 257
H +CQ L + E+ EQDL+LTSEEE +R KG EN QP+K SQEPE+ KD
Sbjct: 351 HVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKD 410
Query: 258 CDRE 261
DRE
Sbjct: 411 GDRE 414
Score = 63.2 bits (152), Expect = 8e-10
Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 10/98 (10%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+FK N+ E+ + N +EVEEEM+KH SN+ L LT+G T GN D
Sbjct: 384 EEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGD 443
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNK 583
+GL NQQ P E+EE+ R + ++ K K
Sbjct: 444 NGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEK 481
Score = 55.5 bits (132), Expect = 2e-07
Identities = 95/394 (24%), Positives = 157/394 (39%), Gaps = 78/394 (19%)
Query: 353 SVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEH--VCQSSSK------LHLHENKLDCD 404
S S+V + + S +++ Y+ S H +CQ S L + + +
Sbjct: 317 SASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPE 376
Query: 405 NDNKLGIGHIFSTDNNFHNDASTKKARNPEV-------VTVEMKEDQEFDLQMTKNMNQ- 456
D KL N K ++ PE+ V EMK+ + ++ + +N+
Sbjct: 377 QDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNG 436
Query: 457 ----NSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVY------LHEELQQDMQKFKNEV 506
N D+G KS P+ + PD++ SE Y L + ++ M K+ +E
Sbjct: 437 VTAGNGDNGLIPQRKSRTPENQQF----PDNE--SEEYHRICELLSDYKEKQMPKYSSEN 490
Query: 507 N--------TLEEEFLALK-KENVQLHKEVEE------------------EMEKHRSNST 539
+ T EEE LK EN Q K +E EM+KHRS
Sbjct: 491 SNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHRSTHV 550
Query: 540 ELSGTLTDGTTVGNDDDGL----------NQQIPRKENEE-HDRPADKTANEKNKVKNQ- 587
LT+G T GN DDGL +QQ P ENEE H + T + + +N
Sbjct: 551 GFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTG 610
Query: 588 -IYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCE 646
++ E + + + + ELS S + +L E + ++ A L DT +
Sbjct: 611 ILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDILHENSTLR-EEIAMLRLELDTM---K 666
Query: 647 HLLKLK-NNHCDQLTVKLKQMENMVSVLQ-NELS 678
H +L+ + + + K+ +N++ LQ NEL+
Sbjct: 667 HQSQLREKKYLEDIESVKKRNDNLLKALQLNELT 700
Score = 47.4 bits (111), Expect = 5e-05
Identities = 24/60 (40%), Positives = 39/60 (65%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K+ VG+ + + A +P++ VR EDL +LHRAA G VP + ++ DT V+K+D++K
Sbjct: 114 KSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQK 173
Score = 43.5 bits (101), Expect = 7e-04
Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 17/141 (12%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKSPSVSPSMPE-N 174
I +L+ +YKEKQ P+ +N+NP+ LT S+E QR K + G P PE N
Sbjct: 471 ICELLSDYKEKQMPKYSSENSNPE-QDLKLT-SEEESQRLKGSENG--QPEKRSQEPEIN 526
Query: 175 QSATKELGQMNLTER------------EKMDTGVVLLSGNDTLHDLCQSQLPENKESKEA 222
+ +EL E E + G +G+D L +S+ PE+++ +
Sbjct: 527 KDGDRELENFMAIEEMKKHRSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDT 586
Query: 223 EQDLELTSEEEQERLKGCENK 243
E + + E+ + + CE +
Sbjct: 587 ENEEYHSDEQNDTQKQFCEEQ 607
>gi|239754871 PREDICTED: similar to Coiled-coil domain-containing
protein 144C [Homo sapiens]
Length = 264
Score = 76.3 bits (186), Expect = 1e-13
Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 26/204 (12%)
Query: 520 NVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGL----------NQQIPRKENEE 569
N++L +VEEEM++HRSN+ +S LTDG T GN DDGL NQQ P ENEE
Sbjct: 29 NIKLPLKVEEEMQRHRSNNVGISENLTDGATAGNGDDGLIPQRKSRKPENQQFPSTENEE 88
Query: 570 HDRPADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEY 629
+ R K EK K + +Y + + E +D E++ + +LR
Sbjct: 89 YHRLTLKQEEEKRKDADMLYKKGS-EELKRKEEEYGKDVEINQQLKRTLKTRAMELRTVR 147
Query: 630 KDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLEL 689
K+ + TF N H + + L + + +N + + + L+LEL
Sbjct: 148 KN------LDQTF---------GNLHSLRFEISLSHKKEKGLLHENSMLQEEIAMLRLEL 192
Query: 690 QKIEWEKELYDLRLALKQENGRKE 713
I+ + E+ + + E+ ++E
Sbjct: 193 DTIKHQNEIKEKKYFEDIESVKEE 216
Score = 32.0 bits (71), Expect = 2.1
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 14/124 (11%)
Query: 185 NLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKES--KEAEQDLELTSEEEQERLKGCEN 242
N+ E + G +G+D L +S+ PEN++ E E+ LT ++E+E+ K +
Sbjct: 47 NVGISENLTDGATAGNGDDGLIPQRKSRKPENQQFPSTENEEYHRLTLKQEEEKRKDADM 106
Query: 243 KQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQRF 302
+K S+E + ++ +D+ I L K+ M +L+ V L Q F
Sbjct: 107 LY-KKGSEELKRKEEEYGKDVEINQQLKRTLKTRAM-----------ELRTVRKNLDQTF 154
Query: 303 GEIY 306
G ++
Sbjct: 155 GNLH 158
>gi|239749410 PREDICTED: similar to Coiled-coil domain-containing
protein 144C [Homo sapiens]
Length = 264
Score = 76.3 bits (186), Expect = 1e-13
Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 26/204 (12%)
Query: 520 NVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGL----------NQQIPRKENEE 569
N++L +VEEEM++HRSN+ +S LTDG T GN DDGL NQQ P ENEE
Sbjct: 29 NIKLPLKVEEEMQRHRSNNVGISENLTDGATAGNGDDGLIPQRKSRKPENQQFPSTENEE 88
Query: 570 HDRPADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEY 629
+ R K EK K + +Y + + E +D E++ + +LR
Sbjct: 89 YHRLTLKQEEEKRKDADMLYKKGS-EELKRKEEEYGKDVEINQQLKRTLKTRAMELRTVR 147
Query: 630 KDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLEL 689
K+ + TF N H + + L + + +N + + + L+LEL
Sbjct: 148 KN------LDQTF---------GNLHSLRFEISLSHKKEKGLLHENSMLQEEIAMLRLEL 192
Query: 690 QKIEWEKELYDLRLALKQENGRKE 713
I+ + E+ + + E+ ++E
Sbjct: 193 DTIKHQNEIKEKKYFEDIESVKEE 216
Score = 32.0 bits (71), Expect = 2.1
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 14/124 (11%)
Query: 185 NLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKES--KEAEQDLELTSEEEQERLKGCEN 242
N+ E + G +G+D L +S+ PEN++ E E+ LT ++E+E+ K +
Sbjct: 47 NVGISENLTDGATAGNGDDGLIPQRKSRKPENQQFPSTENEEYHRLTLKQEEEKRKDADM 106
Query: 243 KQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQRF 302
+K S+E + ++ +D+ I L K+ M +L+ V L Q F
Sbjct: 107 LY-KKGSEELKRKEEEYGKDVEINQQLKRTLKTRAM-----------ELRTVRKNLDQTF 154
Query: 303 GEIY 306
G ++
Sbjct: 155 GNLH 158
>gi|239743545 PREDICTED: hypothetical protein XP_002342885 [Homo
sapiens]
Length = 264
Score = 76.3 bits (186), Expect = 1e-13
Identities = 57/204 (27%), Positives = 93/204 (45%), Gaps = 26/204 (12%)
Query: 520 NVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGL----------NQQIPRKENEE 569
N++L +VEEEM++HRSN+ +S LTDG T GN DDGL NQQ P ENEE
Sbjct: 29 NIKLPLKVEEEMQRHRSNNVGISENLTDGATAGNGDDGLIPQRKSRKPENQQFPSTENEE 88
Query: 570 HDRPADKTANEKNKVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEY 629
+ R K EK K + +Y + + E +D E++ + +LR
Sbjct: 89 YHRLTLKQEEEKRKDADMLYKKGS-EELKRKEEEYGKDVEINQQLKRTLKTRAMELRTVR 147
Query: 630 KDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLEL 689
K+ + TF N H + + L + + +N + + + L+LEL
Sbjct: 148 KN------LDQTF---------GNLHSLRFEISLSHKKEKGLLHENSMLQEEIAMLRLEL 192
Query: 690 QKIEWEKELYDLRLALKQENGRKE 713
I+ + E+ + + E+ ++E
Sbjct: 193 DTIKHQNEIKEKKYFEDIESVKEE 216
Score = 32.0 bits (71), Expect = 2.1
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 14/124 (11%)
Query: 185 NLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKES--KEAEQDLELTSEEEQERLKGCEN 242
N+ E + G +G+D L +S+ PEN++ E E+ LT ++E+E+ K +
Sbjct: 47 NVGISENLTDGATAGNGDDGLIPQRKSRKPENQQFPSTENEEYHRLTLKQEEEKRKDADM 106
Query: 243 KQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEEMWIEQGKLEWKNQLKLVINELKQRF 302
+K S+E + ++ +D+ I L K+ M +L+ V L Q F
Sbjct: 107 LY-KKGSEELKRKEEEYGKDVEINQQLKRTLKTRAM-----------ELRTVRKNLDQTF 154
Query: 303 GEIY 306
G ++
Sbjct: 155 GNLH 158
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Query: 210 QSQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDRE 261
+ L + E+ EQDL+LTSEEE +RLK EN QP+K SQEPE+ KDCDRE
Sbjct: 363 KQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDRE 414
Score = 59.7 bits (143), Expect = 9e-09
Identities = 45/149 (30%), Positives = 70/149 (46%), Gaps = 16/149 (10%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+ K N+ E+ + N +EVEEE++KH SN L LT+G + GN D
Sbjct: 384 EEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGD 443
Query: 556 DGL----------NQQIPRKENEE-HDRPADKTANEKNKVKNQ-IYPEADFADSMEPSEI 603
DGL NQQ P ENEE H + T + ++ +N I + + + E+
Sbjct: 444 DGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEV 503
Query: 604 ASED----CELSHSVYENFMLLIEQLRME 628
A ++ LSH E+ + LR E
Sbjct: 504 AEKEMNSKLSLSHKKEEDLLRENSMLREE 532
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/60 (40%), Positives = 40/60 (66%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K++VG+ + + A +P++ VR EDL +LHRAA G VP + ++ DT ++KRD++K
Sbjct: 114 KSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQK 173
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 15/145 (10%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKS-PSVSPSMPE- 173
I +L+ +YKEKQ + +N+NP+ +L L+ E + S+ LKV + S P PE
Sbjct: 353 ICELLSDYKEKQMLKISSENSNPE---QDLKLTSE--EESQRLKVSENSQPEKMSQEPEI 407
Query: 174 NQSATKEL-------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDL 226
N+ +E+ G + E + G +G+D L +S+ PEN++ + E +
Sbjct: 408 NKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENE- 466
Query: 227 ELTSEEEQERLKGCENKQPQKTSQE 251
E S+E+ + K +Q SQ+
Sbjct: 467 EYHSDEQNDTQKQLSEEQNTGISQD 491
>gi|153792284 pote protein [Homo sapiens]
Length = 584
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Query: 210 QSQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDRE 261
+ L + E+ EQDL+LTSEEE +RLK EN QP+K SQEPE+ KDCDRE
Sbjct: 363 KQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDRE 414
Score = 61.2 bits (147), Expect = 3e-09
Identities = 62/224 (27%), Positives = 95/224 (42%), Gaps = 42/224 (18%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+ K N+ E+ + N +EVEEE++KH SN L LT+G + GN D
Sbjct: 384 EEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGD 443
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
DGL NQQ P ENEE+ ++E+N + Q+ E + S +
Sbjct: 444 DGLIPQRRSRKPENQQFPDTENEEYH------SDEQNDTRKQLSEEQNTGISQD------ 491
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQ 665
+ N IE + SL ++ E L L+ N Q + + +
Sbjct: 492 -------EILTNKQKQIEVAEQKMNSELSLSHKKE-----EDL--LRENSVLQEEIAMLR 537
Query: 666 MENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQEN 709
+E + QN+L E K L++IE KE D L Q N
Sbjct: 538 LELDETKHQNQLRENK------ILEEIESVKEKTDKLLRAMQLN 575
Score = 47.8 bits (112), Expect = 4e-05
Identities = 23/60 (38%), Positives = 39/60 (65%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K++VG+ + A +P++ +R EDL +LHRAA G VP + ++ DT ++KRD++K
Sbjct: 114 KSNVGAWGDYDHSAFMEPRYHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEK 173
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 15/145 (10%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKS-PSVSPSMPE- 173
I +L+ +YKEKQ + +N+NP+ +L L+ E + S+ LKV + S P PE
Sbjct: 353 ICELLSDYKEKQMLKISSENSNPE---QDLKLTSE--EESQRLKVSENSQPEKMSQEPEI 407
Query: 174 NQSATKEL-------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDL 226
N+ +E+ G + E + G +G+D L +S+ PEN++ + E +
Sbjct: 408 NKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENE- 466
Query: 227 ELTSEEEQERLKGCENKQPQKTSQE 251
E S+E+ + K +Q SQ+
Sbjct: 467 EYHSDEQNDTRKQLSEEQNTGISQD 491
>gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens]
Length = 542
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Query: 210 QSQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDRE 261
+ L + E+ EQDL+LTSEEE +RLK EN QP+K SQEPE+ KDCDRE
Sbjct: 363 KQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDRE 414
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 16/114 (14%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+ K N+ E+ + N +EVEEE++KH SN L LT+G + GN D
Sbjct: 384 EEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGD 443
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSME 599
DGL NQQ P ENEE+ ++E+N + Q+ E + S +
Sbjct: 444 DGLIPQRRSRKPENQQFPDTENEEYH------SDEQNDTRKQLSEEQNTGISQD 491
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/60 (40%), Positives = 40/60 (66%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K++VG+ + + A +P++ VR EDL +LHRAA G VP + ++ DT ++KRD++K
Sbjct: 114 KSNVGAWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQK 173
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 15/145 (10%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKS-PSVSPSMPE- 173
I +L+ +YKEKQ + +N+NP+ +L L+ E + S+ LKV + S P PE
Sbjct: 353 ICELLSDYKEKQMLKISSENSNPE---QDLKLTSE--EESQRLKVSENSQPEKMSQEPEI 407
Query: 174 NQSATKEL-------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDL 226
N+ +E+ G + E + G +G+D L +S+ PEN++ + E +
Sbjct: 408 NKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENE- 466
Query: 227 ELTSEEEQERLKGCENKQPQKTSQE 251
E S+E+ + K +Q SQ+
Sbjct: 467 EYHSDEQNDTRKQLSEEQNTGISQD 491
>gi|239747116 PREDICTED: hypothetical protein XP_002343915 isoform 2
[Homo sapiens]
Length = 551
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Query: 210 QSQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDRE 261
+ L + E+ EQDL+LTSEEE +RLK EN QP+K SQEPE+ KDCDRE
Sbjct: 330 KQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDRE 381
Score = 62.4 bits (150), Expect = 1e-09
Identities = 61/227 (26%), Positives = 94/227 (41%), Gaps = 48/227 (21%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+ K N+ E+ + N +EVEEE++KH SN L LT+G + GN D
Sbjct: 351 EEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGD 410
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
DGL NQQ P ENEE+ ++E+N + Q+ E + S +
Sbjct: 411 DGLIPQRRSRKPENQQFPDTENEEYH------SDEQNDTRKQLSEEQNTGISQD------ 458
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQ 665
+ N IE + SL ++ L E+ +
Sbjct: 459 -------EILTNKQKQIEVAEQKMNSELSLSHKKEEDLLRENSV---------------- 495
Query: 666 MENMVSVLQNELSETKKTKLQLE---LQKIEWEKELYDLRLALKQEN 709
++ ++VL+ EL ETK E L++IE KE D L Q N
Sbjct: 496 LQEEIAVLRLELDETKHQNQLRENKILEEIESVKEKTDKLLRAMQLN 542
Score = 48.1 bits (113), Expect = 3e-05
Identities = 24/60 (40%), Positives = 39/60 (65%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K++VG+ + A +P++ VR EDL +LHRAA G VP + ++ DT ++KRD++K
Sbjct: 81 KSNVGAWGDYDHSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEK 140
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 15/145 (10%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKS-PSVSPSMPE- 173
I +L+ +YKEKQ + +N+NP+ +L L+ E + S+ LKV + S P PE
Sbjct: 320 ICELLSDYKEKQMLKISSENSNPE---QDLKLTSE--EESQRLKVSENSQPEKMSQEPEI 374
Query: 174 NQSATKEL-------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDL 226
N+ +E+ G + E + G +G+D L +S+ PEN++ + E +
Sbjct: 375 NKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENE- 433
Query: 227 ELTSEEEQERLKGCENKQPQKTSQE 251
E S+E+ + K +Q SQ+
Sbjct: 434 EYHSDEQNDTRKQLSEEQNTGISQD 458
>gi|239747114 PREDICTED: hypothetical protein XP_002343914 isoform 1
[Homo sapiens]
Length = 584
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Query: 210 QSQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDRE 261
+ L + E+ EQDL+LTSEEE +RLK EN QP+K SQEPE+ KDCDRE
Sbjct: 363 KQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDRE 414
Score = 62.4 bits (150), Expect = 1e-09
Identities = 61/227 (26%), Positives = 94/227 (41%), Gaps = 48/227 (21%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+ K N+ E+ + N +EVEEE++KH SN L LT+G + GN D
Sbjct: 384 EEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGD 443
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
DGL NQQ P ENEE+ ++E+N + Q+ E + S +
Sbjct: 444 DGLIPQRRSRKPENQQFPDTENEEYH------SDEQNDTRKQLSEEQNTGISQD------ 491
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQ 665
+ N IE + SL ++ L E+ +
Sbjct: 492 -------EILTNKQKQIEVAEQKMNSELSLSHKKEEDLLRENSV---------------- 528
Query: 666 MENMVSVLQNELSETKKTKLQLE---LQKIEWEKELYDLRLALKQEN 709
++ ++VL+ EL ETK E L++IE KE D L Q N
Sbjct: 529 LQEEIAVLRLELDETKHQNQLRENKILEEIESVKEKTDKLLRAMQLN 575
Score = 48.1 bits (113), Expect = 3e-05
Identities = 24/60 (40%), Positives = 39/60 (65%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K++VG+ + A +P++ VR EDL +LHRAA G VP + ++ DT ++KRD++K
Sbjct: 114 KSNVGAWGDYDHSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEK 173
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 15/145 (10%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKS-PSVSPSMPE- 173
I +L+ +YKEKQ + +N+NP+ +L L+ E + S+ LKV + S P PE
Sbjct: 353 ICELLSDYKEKQMLKISSENSNPE---QDLKLTSE--EESQRLKVSENSQPEKMSQEPEI 407
Query: 174 NQSATKEL-------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDL 226
N+ +E+ G + E + G +G+D L +S+ PEN++ + E +
Sbjct: 408 NKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRRSRKPENQQFPDTENE- 466
Query: 227 ELTSEEEQERLKGCENKQPQKTSQE 251
E S+E+ + K +Q SQ+
Sbjct: 467 EYHSDEQNDTRKQLSEEQNTGISQD 491
>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
sapiens]
Length = 544
Score = 65.5 bits (158), Expect = 2e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Query: 210 QSQLPENKESKEAEQDLELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDRE 261
+ L + E+ EQDL+LTSEEE +RLK EN QP+K SQEPE+ KDCDRE
Sbjct: 326 KQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDRE 377
Score = 60.1 bits (144), Expect = 7e-09
Identities = 52/212 (24%), Positives = 93/212 (43%), Gaps = 31/212 (14%)
Query: 496 QQDMQKFKNEVNTLEEEFLALKKENVQLHKEVEEEMEKHRSNSTELSGTLTDGTTVGNDD 555
+++ Q+ K N+ E+ + N +EVEEE++KH SN L LT+G + GN D
Sbjct: 347 EEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGD 406
Query: 556 DGL----------NQQIPRKENEEHDRPADKTANEKNKVKNQIYPEADFADSMEPSEIAS 605
DGL NQQ P ENEE+ ++E+N + Q+ E + S +
Sbjct: 407 DGLIPQRKSRKPENQQFPDTENEEYH------SDEQNDTQKQLSEEQNTGISQD------ 454
Query: 606 EDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQ 665
+ N IE E SL ++ L E+ + +L ++L +
Sbjct: 455 -------EILTNKQKQIEVAEKEMNSELSLSHKKEEDLLREN--SMLREEIAKLRLELDE 505
Query: 666 MENMVSVLQNELSETKKTKLQLELQKIEWEKE 697
++ + +N++ E ++ + L+ I+ +E
Sbjct: 506 TKHQNQLRENKILEEIESVKEKLLKTIQLNEE 537
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/60 (40%), Positives = 40/60 (66%)
Query: 55 KNSVGSESKHGEGALDQPQHDVRLEDLGELHRAARSGDVPGVEHVLAPGDTGVDKRDRKK 114
K++VG+ + + A +P++ VR EDL +LHRAA G VP + ++ DT ++KRD++K
Sbjct: 77 KSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQK 136
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 15/145 (10%)
Query: 116 IQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVGDKS-PSVSPSMPE- 173
I +L+ +YKEKQ + +N+NP+ +L L+ E + S+ LKV + S P PE
Sbjct: 316 ICELLSDYKEKQMLKISSENSNPE---QDLKLTSE--EESQRLKVSENSQPEKMSQEPEI 370
Query: 174 NQSATKEL-------GQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEAEQDL 226
N+ +E+ G + E + G +G+D L +S+ PEN++ + E +
Sbjct: 371 NKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENE- 429
Query: 227 ELTSEEEQERLKGCENKQPQKTSQE 251
E S+E+ + K +Q SQ+
Sbjct: 430 EYHSDEQNDTQKQLSEEQNTGISQD 454
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,882,627
Number of Sequences: 37866
Number of extensions: 1483539
Number of successful extensions: 9140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 517
Number of HSP's that attempted gapping in prelim test: 6978
Number of HSP's gapped (non-prelim): 2313
length of query: 725
length of database: 18,247,518
effective HSP length: 110
effective length of query: 615
effective length of database: 14,082,258
effective search space: 8660588670
effective search space used: 8660588670
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.