Search of human proteins with 239742950

Search of human proteins with 239742950

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239742950 PREDICTED: hypothetical protein XP_002342702 [Homo
sapiens]
         (709 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239742950 PREDICTED: hypothetical protein XP_002342702 [Homo ...  1447   0.0  
gi|239754438 PREDICTED: hypothetical protein [Homo sapiens]          1439   0.0  
gi|239748928 PREDICTED: hypothetical protein XP_002346859 [Homo ...  1439   0.0  
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            49   1e-05
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]            48   4e-05
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]            47   8e-05
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]          47   8e-05
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             46   1e-04
gi|27437008 kringle-containing transmembrane protein 2 isoform d...    44   5e-04
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      44   7e-04
gi|169179422 PREDICTED: hypothetical protein [Homo sapiens]            44   7e-04
gi|122692281 hypothetical protein LOC645369 [Homo sapiens]             43   0.001
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   0.002
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    42   0.002
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       42   0.002
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       42   0.002
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     42   0.002
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    42   0.002
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         42   0.002
gi|153792074 proline rich 12 [Homo sapiens]                            42   0.003
gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo sa...    41   0.004
gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo s...    41   0.004
gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo s...    41   0.004
gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo s...    41   0.004
gi|239743072 PREDICTED: hypothetical protein [Homo sapiens]            41   0.004
gi|239508718 PREDICTED: hypothetical protein [Homo sapiens]            41   0.004
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                41   0.004
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                40   0.006
gi|148886696 surfactant protein A2 [Homo sapiens]                      40   0.007

>gi|239742950 PREDICTED: hypothetical protein XP_002342702 [Homo
           sapiens]
          Length = 709

 Score = 1447 bits (3746), Expect = 0.0
 Identities = 709/709 (100%), Positives = 709/709 (100%)

Query: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60
           MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP
Sbjct: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60

Query: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120
           LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR
Sbjct: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120

Query: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180
           GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF
Sbjct: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180

Query: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240
           HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV
Sbjct: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240

Query: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLGGWLRALRG 300
           VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLGGWLRALRG
Sbjct: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLGGWLRALRG 300

Query: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360
           PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA
Sbjct: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360

Query: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420
           FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS
Sbjct: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420

Query: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480
           GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS
Sbjct: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480

Query: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCA 540
           STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCA
Sbjct: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCA 540

Query: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600
           WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK
Sbjct: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600

Query: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660
           RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ
Sbjct: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660

Query: 661 RNRLRVTHPPESAPGEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709
           RNRLRVTHPPESAPGEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR
Sbjct: 661 RNRLRVTHPPESAPGEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709


>gi|239754438 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 709

 Score = 1439 bits (3726), Expect = 0.0
 Identities = 706/709 (99%), Positives = 706/709 (99%)

Query: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60
           MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP
Sbjct: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60

Query: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120
           LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR
Sbjct: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120

Query: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180
           GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF
Sbjct: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180

Query: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240
           HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV
Sbjct: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240

Query: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLGGWLRALRG 300
           VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPL GWLRALRG
Sbjct: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG 300

Query: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360
           PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA
Sbjct: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360

Query: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420
           FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS
Sbjct: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420

Query: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480
           GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS
Sbjct: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480

Query: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCA 540
           STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGV EGCA
Sbjct: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA 540

Query: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600
           WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK
Sbjct: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600

Query: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660
           RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ
Sbjct: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660

Query: 661 RNRLRVTHPPESAPGEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709
           RNRLRVTHPPESAP EVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR
Sbjct: 661 RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709


>gi|239748928 PREDICTED: hypothetical protein XP_002346859 [Homo
           sapiens]
          Length = 709

 Score = 1439 bits (3726), Expect = 0.0
 Identities = 706/709 (99%), Positives = 706/709 (99%)

Query: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60
           MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP
Sbjct: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60

Query: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120
           LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR
Sbjct: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120

Query: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180
           GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF
Sbjct: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180

Query: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240
           HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV
Sbjct: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240

Query: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLGGWLRALRG 300
           VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPL GWLRALRG
Sbjct: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG 300

Query: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360
           PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA
Sbjct: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360

Query: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420
           FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS
Sbjct: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420

Query: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480
           GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS
Sbjct: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480

Query: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCA 540
           STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGV EGCA
Sbjct: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA 540

Query: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600
           WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK
Sbjct: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600

Query: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660
           RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ
Sbjct: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660

Query: 661 RNRLRVTHPPESAPGEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709
           RNRLRVTHPPESAP EVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR
Sbjct: 661 RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 107/417 (25%), Positives = 143/417 (34%), Gaps = 72/417 (17%)

Query: 273 AVCAAPSAGGSPGKSDA----PLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVG 328
           A C +PSA G+   SD+    P   W+         SS     +   +  S  +   WV 
Sbjct: 230 ASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVC 289

Query: 329 DPGAPLTPRKASCSWPAPGEASSPGL-RAGVSAFSCLEEFPGEECSCLAVVVASGKGSPS 387
              +  +   +  S P+   +SSP + RA   + S    F     S  +    SG  S S
Sbjct: 290 PSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPS---DSGWTSHS 346

Query: 388 ASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSG---------SSPSASRG 438
           AS  S   +S  W   +A+ A+     G +S S   A P  SG         +SPSAS  
Sbjct: 347 ASGVSTTSDS-GWASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGA 405

Query: 439 FSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLG---GSK 495
                PS     CF         P L A +  TV     S  S C    L + G     +
Sbjct: 406 SMPSAPSLCPGSCF---------PQLTARTGFTVVGFPFSLLSHCISLCLPEFGIFVSVE 456

Query: 496 HLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCAWDSAYSAP----GPV 551
            L P LA   +  +R  +  R  P L S      PS  GV  G A D     P     P+
Sbjct: 457 SLAP-LAILTLVHSRPLAQPRPQPSLSSLDS---PSARGVRVGLARDHLCCLPISVFSPL 512

Query: 552 PRHT----------------CGSGVARLEPQGPAHLCEGAGPPAND-------PQRSQEG 588
           P                   CG G  R      AH    AG    +        Q + +G
Sbjct: 513 PLQNLLQVKGLFDGTSGCPHCGLGGHR------AHFLPHAGLAGTELLPLRLLAQLAPQG 566

Query: 589 GKPGLLISPGAKRLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFR 645
              G L+  G       A+   REG +     +  P    AL GL E     G P+R
Sbjct: 567 CAEGWLVLQGEGE-GPQAQGPLREGRE----VSQAPETVSALLGLQEQLPGEGLPWR 618



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 23/177 (12%)

Query: 276 AAPSAGGSPGKSDAPLGGWLR-ALRGPREPS-------SAHTLGAPLGASPSPPAGRSWV 327
           A+PSA G+   SD+   GW   +  G   PS       SA     P  +  + P+  SW 
Sbjct: 37  ASPSASGASIPSDS---GWASPSASGASTPSNSGWASFSASWASIPSDSGWASPSA-SWA 92

Query: 328 GDPGAP--LTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGS 385
             P      +P  +  S P+    +SP + +G S  S     P    S  +    SG  S
Sbjct: 93  STPSDSGWASPSASGASIPSDSGWASPSV-SGASIPSAFWASPS--ASGASTPSDSGWAS 149

Query: 386 PSAS-----RGSNWGE-SFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSAS 436
           PSAS       S W   S SW   +A+ A+       + +  G A P +   SPS S
Sbjct: 150 PSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASPSVFWVSPSTS 206


>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/382 (27%), Positives = 132/382 (34%), Gaps = 84/382 (21%)

Query: 19  AEMVPGLQAVGVRSSRR----SGRSAQLSASTSLCPAVEVVGERAPLVLGLDLRQQRAAL 74
           A+  P   A G RSS R     GR     A T            AP+      R +R  L
Sbjct: 34  AQPPPHTPATGTRSSYRLLPQKGRGNLRGAPT------------APVSFS---RIRRNPL 78

Query: 75  DRELAGDGPRRLLPALG-RSALGDWAGIGHP-LGWGLLGGSPGAA----GGRGGHGLEGT 128
             +L+G  PRR    L   S  GD      P  G G     P       GGR G   EG 
Sbjct: 79  RTQLSGSPPRRPTSVLRLASPAGDLPRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGR 138

Query: 129 APALPLRG-GRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRFHFLFRRG 187
                LRG G+ RGW   P R+ S L     AGLG  A  GG A   G            
Sbjct: 139 GA---LRGSGKRRGWGLRPQRVRSRL-----AGLG--APRGGAAAPRGW----------- 177

Query: 188 VIAGRVWRHLVVEHRVVPG-SALRELGVRAGGVGGFLRPPPP---------PRPTAA--- 234
              G+    L V    +P  +ALR  G  + G GG  RP PP         PRP      
Sbjct: 178 --GGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLL 235

Query: 235 GPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAP---- 290
           G         A+ R G        +   S  + A   ++  A P+ GG+ G   A     
Sbjct: 236 GSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295

Query: 291 ------------LGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRK 338
                         G L+  RG +   +AH   +    SP P A RS +     PL    
Sbjct: 296 GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASRSTLAAQLLPLPQP- 354

Query: 339 ASCSWPAPGEASSPGLRAGVSA 360
                P P + + P L   +SA
Sbjct: 355 -----PPPPKLAPPPLPPWLSA 371


>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 106/382 (27%), Positives = 132/382 (34%), Gaps = 84/382 (21%)

Query: 19  AEMVPGLQAVGVRSSRR----SGRSAQLSASTSLCPAVEVVGERAPLVLGLDLRQQRAAL 74
           A+  P   A G RSS R     GR     A T            AP+      R +R  L
Sbjct: 34  AQPPPHTPATGTRSSYRLLPQKGRGNLRGAPT------------APVSFS---RIRRNPL 78

Query: 75  DRELAGDGPRRLLPALG-RSALGDWAGIGHP-LGWGLLGGSPGAA----GGRGGHGLEGT 128
             +L+G  PRR    L   S  GD      P  G G     P       GGR G   EG 
Sbjct: 79  RTQLSGSPPRRPTSVLRLASPAGDLPRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGR 138

Query: 129 APALPLRG-GRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRFHFLFRRG 187
                LRG G+ RGW   P R+ S L     AGLG  A  GG A   G            
Sbjct: 139 GA---LRGSGKRRGWGLRPQRVRSRL-----AGLG--APRGGAAAPRGW----------- 177

Query: 188 VIAGRVWRHLVVEHRVVPG-SALRELGVRAGGVGGFLRPPPP---------PRPTAA--- 234
              G+    L V    +P  +ALR  G  + G GG  RP PP         PRP      
Sbjct: 178 --GGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLL 235

Query: 235 GPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAP---- 290
           G         A+ R G        +   S  + A   ++  A P+ GG+ G   A     
Sbjct: 236 GSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295

Query: 291 ------------LGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRK 338
                         G L+  RG +   +AH   +    SP P A RS +     PL    
Sbjct: 296 GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASRSTLAAQLLPLPQP- 354

Query: 339 ASCSWPAPGEASSPGLRAGVSA 360
                P P + + P L   +SA
Sbjct: 355 -----PPPPKLAPPPLPPWLSA 371


>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 105/382 (27%), Positives = 132/382 (34%), Gaps = 84/382 (21%)

Query: 19  AEMVPGLQAVGVRSSRR----SGRSAQLSASTSLCPAVEVVGERAPLVLGLDLRQQRAAL 74
           A+  P   A G RSS R     GR     A T            AP+      R +R  L
Sbjct: 34  AQPPPHTPATGTRSSYRLLPQKGRGNLRGAPT------------APVSFS---RIRRNPL 78

Query: 75  DRELAGDGPRRLLPALG-RSALGDWAGIGHP-LGWGLLGGSPGAA----GGRGGHGLEGT 128
             +L+G  PRR    L   S  GD      P  G G     P       GGR G   EG 
Sbjct: 79  RTQLSGSPPRRPTSVLRLASPAGDLPRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGR 138

Query: 129 APALPLRG-GRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRFHFLFRRG 187
                +RG G+ RGW   P R+ S L     AGLG  A  GG A   G            
Sbjct: 139 GA---VRGSGKRRGWGLRPQRVRSRL-----AGLG--APRGGAAAPRGW----------- 177

Query: 188 VIAGRVWRHLVVEHRVVPG-SALRELGVRAGGVGGFLRPPPP---------PRPTAA--- 234
              G+    L V    +P  +ALR  G  + G GG  RP PP         PRP      
Sbjct: 178 --GGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLL 235

Query: 235 GPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAP---- 290
           G         A+ R G        +   S  + A   ++  A P+ GG+ G   A     
Sbjct: 236 GSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295

Query: 291 ------------LGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRK 338
                         G L+  RG +   +AH   +    SP P A RS +     PL    
Sbjct: 296 GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASRSTLAAQLLPLPQP- 354

Query: 339 ASCSWPAPGEASSPGLRAGVSA 360
                P P + + P L   +SA
Sbjct: 355 -----PPPPKLAPPPLPPWLSA 371


>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
          Length = 903

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 66/237 (27%), Positives = 93/237 (39%), Gaps = 47/237 (19%)

Query: 274 VCAAPSAGGSPGKSDAPLGGWLRALRGP--REPSSAHTLGAPLGASPSPPAGRSWVGDP- 330
           VC A    G   +S  P+    + + GP   EP++A    AP      P AG    G P 
Sbjct: 375 VCQASQLQGQKEESCVPVHQ--KTVLGPDTAEPATAEAAVAP------PDAGLPLPGLPA 426

Query: 331 -GAPLTPRKASCS---WPAPGEASSPGLRAG-VSAFSCL------EEFPG------EECS 373
            G+P      SC      +P + S P + A  +S  SCL      EE P       E+ +
Sbjct: 427 EGSPPPKTYVSCLKSLLSSPTKDSKPNISAHHISLASCLALTTPSEELPDRAGILVEDAT 486

Query: 374 CLAVVVASGKGSPSASRGSNWGESFSWH----CCTATAAALLLQRGDSSASGGAAGPPLS 429
           C+  +  S +  P  +   +  +SFS       CT T+         SS    A  PPL 
Sbjct: 487 CVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETS---------SSPRDKAITPPLP 537

Query: 430 GSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMK 486
            S+   S G  +GE S L      G ED       A  S  + R+ + S  S C++K
Sbjct: 538 ESTVPFSNGVLKGELSDL------GAEDGWTMDAEADHSGGSDRNSMDSVDSCCSLK 588


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 82/335 (24%), Positives = 116/335 (34%), Gaps = 71/335 (21%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSP 284
           P PPPR + AGP++ V P   +  + S    LV   P     +     A  +AP+   +P
Sbjct: 21  PSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLV--APGEARPAWVPGSAETSAPAPAPAP 78

Query: 285 GKSDAPLGGWLRAL--------------RGPREPSSAHTLGAPLG--------------A 316
             + A  G  +  L               GP  P  A   G                  A
Sbjct: 79  APAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEA 138

Query: 317 SPSPPAGRSWVGDPGAPLTPRKASCSWPAPGE-------ASSPG--LRAGVSAFSCLEEF 367
            PSP  G      PG P      + S  APG        A  PG  + +GV+A S   + 
Sbjct: 139 RPSPAPG------PGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQV 192

Query: 368 PGEECSCLAVVVASGKGSPSASRGSNWGESFSWHC----CTATAAALLLQRGDSSASGGA 423
            G   +  A   ++G+ +P    G   G S +        T T A    +      S  +
Sbjct: 193 TGGHGAAAATSASAGQ-APEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSS 251

Query: 424 AGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTC 483
            GP +SG    A    S  +  SL+S       D+               S +GS  S  
Sbjct: 252 LGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDV--------------SSMGS-DSEI 296

Query: 484 NMKTLSK------LGGSKHLGPALAGAPMGGARER 512
           N   L K      LGGS++ G   +  P+  AR+R
Sbjct: 297 NGLALRKTDKYGFLGGSQYSGSLESSIPVDVARQR 331


>gi|27437008 kringle-containing transmembrane protein 2 isoform d
           precursor [Homo sapiens]
          Length = 462

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 59/190 (31%), Positives = 67/190 (35%), Gaps = 49/190 (25%)

Query: 288 DAPLGGWLRALRGPREPSS-------------------AHTLGAPL------GASPSPPA 322
           DA  G  LRA  G R P S                    H  G  L       A+  P A
Sbjct: 276 DAASGSLLRAFDGARPPPSGPLRLGTAALLLTFRSDARGHAQGFALTYRGLQDAAEDPEA 335

Query: 323 GRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEF------------PGE 370
                  P APL     SCS P PG   +P    G   FS +               P  
Sbjct: 336 PEGSAQTPAAPLDGANVSCS-PRPG---APPAAIGARVFSTVTAVSVLLLLLLGLLRPLR 391

Query: 371 ECSCLAVVVASGKGSPSASRGSNWGESFSWHCC--TATAAALLLQRGDSSASGGAAG-PP 427
             SCL   +A GKG P+   G++ G   SW          AL    GD  A G AAG  P
Sbjct: 392 RRSCL---LAPGKGPPAL--GASRGPRRSWAVWYQQPRGVALPCSPGDPQAEGSAAGYRP 446

Query: 428 LSGSSPSASR 437
           LS SS S+ R
Sbjct: 447 LSASSQSSLR 456


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 99/393 (25%), Positives = 127/393 (32%), Gaps = 64/393 (16%)

Query: 278  PSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAP-LTP 336
            P A G PG    P         GP  PS     G+P    P  PAG +  G PG+P ++ 
Sbjct: 869  PGAAGFPGARGLPGPPGSNGNPGPPGPS-----GSPGKDGPPGPAGNT--GAPGSPGVSG 921

Query: 337  RKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSAS---RGSN 393
             K       PGE  SPG +    A       PG       +  A G   P      RGS 
Sbjct: 922  PKGDAG--QPGEKGSPGAQGPPGA-------PGP-LGIAGITGARGLAGPPGMPGPRGSP 971

Query: 394  WGESFSWHCCTATAAALLLQRGDSSASG-----GAAGPPLSGSSPSASRGFSRGEPSSLV 448
              +          A  L  +RG     G     G AG P    +P      S G P    
Sbjct: 972  GPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG-----SDGLPGRDG 1026

Query: 449  SVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGG 508
            S   +G   E   P      +     H G              G S   GPA A  P G 
Sbjct: 1027 SPGGKGDRGENGSP-----GAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG- 1080

Query: 509  ARERSNTRVIPRLQSASERLLPSRG--GVAEGCAWDSAYSAPG-PVPRHTCGSGVARLEP 565
                S     P+     +     RG  G+     +     APG P P    G+ +    P
Sbjct: 1081 ----SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGA-IGSPGP 1135

Query: 566  QGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANPP- 624
             GP      +GPP  D       G PG +  PG +    +   R  EG+   P +  PP 
Sbjct: 1136 AGPRGPVGPSGPPGKDGT----SGHPGPIGPPGPR---GNRGERGSEGSPGHPGQPGPPG 1188

Query: 625  -----------MGAVALRGLPEWGLATGAPFRG 646
                       +GA A+ G+        AP+ G
Sbjct: 1189 PPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYG 1221



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 84/350 (24%), Positives = 108/350 (30%), Gaps = 51/350 (14%)

Query: 282 GSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAP--LTPRKA 339
           G+PG+   P    L    G R    A       G  P PP    + G PGA   + P  +
Sbjct: 303 GAPGERGRP---GLPGAAGARGNDGARGSDGQPGP-PGPPGTAGFPGSPGAKGEVGPAGS 358

Query: 340 SCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFS 399
             S  APG+   PG +    A                     G   P    GS  G+   
Sbjct: 359 PGSNGAPGQRGEPGPQGHAGA--------------------QGPPGPPGINGSPGGKGEM 398

Query: 400 WHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEE 459
                  A  L+  RG    +G    P L G +    +  ++GEP        RG+  E 
Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP------RGERGEA 452

Query: 460 KKP-VLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALA-GAP--MGGARERSNT 515
             P V  A          G   +        + G     GPA   G P   G A ER   
Sbjct: 453 GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAP 512

Query: 516 RVIPRLQSASERLLPSRGGVAEGCAWDSAYSAPGPVPRHTCGSGV-ARLEPQGPAHLCEG 574
                  +A E   P R GV  G        +PG       G G   +  P G       
Sbjct: 513 GPAGPRGAAGE---PGRDGVPGGPGMRGMPGSPG-------GPGSDGKPGPPGSQGESGR 562

Query: 575 AGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANPP 624
            GPP     R    G+PG++  PG K    +       G    P    PP
Sbjct: 563 PGPPGPSGPR----GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP 608



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 102/414 (24%), Positives = 132/414 (31%), Gaps = 65/414 (15%)

Query: 268 ACAELAVCAAPSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWV 327
           A  E+    +P + G+PG+   P         GP+  + A     P G + S P G+  +
Sbjct: 349 AKGEVGPAGSPGSNGAPGQRGEP---------GPQGHAGAQGPPGPPGINGS-PGGKGEM 398

Query: 328 GDPGAPLTPRKASCSWPAPGEA---SSPGLR--AGVSAFSCLEEFPGE-----ECSCLAV 377
           G  G P  P       P PG A    +PGLR  AG    +  +  PG      E     V
Sbjct: 399 GPAGIPGAPGLMGARGP-PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGV 457

Query: 378 VVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASG--GAAGPPLSGSSPSA 435
             A G+     S G               A  L    G+  A G  G AGP  +G     
Sbjct: 458 PGAKGEDGKDGSPGE------------PGANGLPGAAGERGAPGFRGPAGP--NGIPGEK 503

Query: 436 SRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSK 495
                RG P         G+   +  P       R +    G   S          G S 
Sbjct: 504 GPAGERGAPGPAGPRGAAGEPGRDGVP--GGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561

Query: 496 HLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVA----EGCAWDSAYSAPGPV 551
             GP     P G           P+    +      RGG      +G    +  + P   
Sbjct: 562 RPGPPGPSGPRGQPGVMGFPG--PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGP 619

Query: 552 PRHTCGSG----VARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSAR 607
           P  T   G         PQG   L    GPP        E GKPG    PG K  A +  
Sbjct: 620 PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG-------ENGKPG---EPGPKGDAGAPG 669

Query: 608 ARRREGAQNKPIKANPP--MGAVALRGLPEWGLATGAPFRGRGGSAATREPQSA 659
           A   +G    P +  PP   GA  LRG    G     P  G+G +     P +A
Sbjct: 670 APGGKGDAGAPGERGPPGLAGAPGLRG----GAGPPGPEGGKGAAGPPGPPGAA 719



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 100/389 (25%), Positives = 121/389 (31%), Gaps = 83/389 (21%)

Query: 277 APSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASP-SPPAGRSWVGDPGAPLT 335
           AP A G  G + AP        RGP  P  A   G   GA P  P  G+   G PG    
Sbjct: 667 APGAPGGKGDAGAP------GERGP--PGLAGAPGLRGGAGPPGPEGGKGAAGPPG---- 714

Query: 336 PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPS--ASRGSN 393
                     PG A +PGL+            PGE     +      KG P    + G  
Sbjct: 715 ---------PPGAAGTPGLQG----------MPGERGGLGSPGPKGDKGEPGGPGADGVP 755

Query: 394 WGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFR 453
             +                Q GD    G    P ++G  P  S G  RGE        F 
Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAG--PRGSPG-ERGETGPPGPAGFP 812

Query: 454 GKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGGARERS 513
           G   +  +P       +  R   G              GGS   GPA    P G   ER 
Sbjct: 813 GAPGQNGEP-----GGKGERGAPGEKGEGGPPGVAGPPGGS---GPAGPPGPQGVKGERG 864

Query: 514 NTRVIPRLQSASERLLPSRGGVAEGCAWDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCE 573
           +               P   G A    +  A   PGP P      G     P GP     
Sbjct: 865 S---------------PGGPGAA---GFPGARGLPGP-PGSNGNPG-----PPGP----- 895

Query: 574 GAGPPAND--PQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANPPMGAVALR 631
            +G P  D  P  +   G PG     G K  A     +   GAQ  P  A  P+G   + 
Sbjct: 896 -SGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPP-GAPGPLGIAGIT 953

Query: 632 GLPEWGLATGAPFRGRGGSAATREPQSAQ 660
           G    GLA G P  G  G   +  PQ  +
Sbjct: 954 GAR--GLA-GPP--GMPGPRGSPGPQGVK 977


>gi|169179422 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 645

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 95/365 (26%), Positives = 122/365 (33%), Gaps = 79/365 (21%)

Query: 264 LTQSACAELAVCAAPSAGGSPGKSDAPLGGWLRALRGPREPSS-------AHTLGAPL-G 315
           +    C E A    P  GG  G      GG       P  PSS          L APL  
Sbjct: 283 INMDVCEEPASRTMPYCGGGGGSQPGVSGG--PDTLTPNSPSSFLPSSFLLCLLPAPLTA 340

Query: 316 ASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSAFSC--LEEFPGEECS 373
           A P    GR                    APGE   P L  G+ A SC  + + PG+  +
Sbjct: 341 AQPEDAGGR--------------------APGEEGPPRLAVGLRASSCPIILDPPGKLGT 380

Query: 374 CLAVVVAS-----GKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPL 428
            L    A+     G+ SPS  R     E      CTAT  +       +S S    G  L
Sbjct: 381 SLPGPGANSSLREGRTSPSRPRLPQSPEHQQVSACTATWPSCRAAELPASDSPSGWGTWL 440

Query: 429 SGSSP-SASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKT 487
           S   P   ++G                K    +   L  + SR   S+L  T   C+ + 
Sbjct: 441 STPPPYKPNKGL---------------KGPTRRSLGLLEWRSRLACSNLLRTGQGCSGQA 485

Query: 488 LSKLGGSKHL-----GPALAGAPMG-----GARERSNTRVIPRLQSASERLLPSRGGVAE 537
           L + G ++ L     G    G P+G     GA  R +   I  L          RG    
Sbjct: 486 LLRCGSNRTLRGGGTGQKWPGVPLGARTGLGAGVRQHPGGIAGLSR-------ERGHSPW 538

Query: 538 GCAWDSAYSA--PGPVPRHTCGSGVARLE-----PQGPAHLCEGAGPPANDPQRSQEGGK 590
               DSA  A  PG VP      G A        P   A   E   PP+  P  ++ GG 
Sbjct: 539 AALTDSAAGAELPGLVPSAPRRPGSATAPRPLRVPGRGAQSAEPGTPPS--PPGAEHGGG 596

Query: 591 PGLLI 595
           PGL++
Sbjct: 597 PGLIL 601


>gi|122692281 hypothetical protein LOC645369 [Homo sapiens]
          Length = 621

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 93/396 (23%), Positives = 135/396 (34%), Gaps = 72/396 (18%)

Query: 267 SACAELAVCAAPSAGGSPGKSDA---PLGGWLRALRG---PREPSSAHTLGAPLGASPSP 320
           +A A  A  AA S+  +P  +     PL G+L  ++      +P      G   GA+   
Sbjct: 220 AAAAAAAAAAASSSSSAPAAAPPGAIPLNGFLSYVQSRGLELKPGGCGGSGDAFGAAAML 279

Query: 321 PAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGL-----RAGVSAFSCLEEFPG-----E 370
             G SW   P AP   R    + P P  ASSP           + +S   E  G      
Sbjct: 280 AKG-SWPPHPAAPSGGRPRGAASP-PDLASSPRCPREPPSLAEAVYSVYRERSGVAGSRR 337

Query: 371 ECSCLAVVVASGKGSPS-ASRGSNWGE---SFSWHCCTATAAALLLQRGDSSASGGAAGP 426
             +  A   AS   SP+  S   +WG    + S+   + +A ALL  +G     G A G 
Sbjct: 338 AAAATAAAAASSCSSPAPCSPPESWGRQSTASSFVDSSLSAFALLPLQGGRDRGGDAEGA 397

Query: 427 PLSGSSPSASRG---FSRGEPSSLVSVCFRG---------KEDEEKKPVLAAFSSRTVRS 474
             S   P   RG     RGE   L     RG         +E EE +  +AA ++R    
Sbjct: 398 SCSWQRPPGERGSQEIPRGE-LDLSMTNLRGAEGSMRGARREPEEPEGAVAARAARGQGG 456

Query: 475 HLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGG 534
            L  T     ++  S  G   +  P     P                        PS G 
Sbjct: 457 RLPRTGRYAALRRRSTSGLPDYRAPPSPEPP------------------------PSPG- 491

Query: 535 VAEGCAWDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLL 594
                   SA     P+ +    S   RLE   P     G+   ++DP  S +G  P   
Sbjct: 492 --------SADPDSSPLAKAASPSPPLRLEGSPPTRRDSGSS-QSDDPSSSNKGYTPLRE 542

Query: 595 ISPGAKRLASSARARRREGAQNKPI---KANPPMGA 627
                + +  +   + R+ A   P+   + + P GA
Sbjct: 543 AGTSTESVLDAVAGQTRDSAVAAPVLGAEQSSPEGA 578


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 106/439 (24%), Positives = 147/439 (33%), Gaps = 71/439 (16%)

Query: 276 AAPSAGGSPGKSDAPLGGWLRALRGPREPSS--AHTLGAPLGASPSPPAGRSWVGDPGAP 333
           A PS   SP  S  PL     A   P+ P++   H L AP    PSPP    +      P
Sbjct: 407 APPSPPASPPLS--PL-----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459

Query: 334 LTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSN 393
           ++P     S   P  A+ P           L+  P           AS   SPSA+    
Sbjct: 460 VSPSATPPSQAPPSLAAPP-----------LQVPPSPP--------ASPPMSPSATPPPQ 500

Query: 394 WGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSG--SSPSASRGFSRGEPSSLVSVC 451
                +       A  L L +    A    A PPL    S P++  G +   PS+ + + 
Sbjct: 501 APPPLA-------APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 553

Query: 452 FRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALA-----GAPM 506
                  +  PVLAA   +   S   S +     +  +    +   GP L      G P 
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613

Query: 507 GGARERSNTRVIPRL--QSASERLLPSR-GGVAEGCAWDSAYSAPGPVPRHTCGSGVARL 563
             +R  S+T   P L   S+S    P    G   G    +A S P       C       
Sbjct: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673

Query: 564 EPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANP 623
            P  P       G P   P  +  G   GL                  EG    P  A P
Sbjct: 674 GPAPPLAFRGAPGAPLPWPPATGPGSADGL------------CTIYETEG----PESATP 717

Query: 624 PMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQRNRLRVTHPPESAPGEVRMNQIC 683
             GA  L   P  G + G    G G  A++R P+ A+   L +        G ++ + + 
Sbjct: 718 APGA--LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL--------GALQASVVQ 767

Query: 684 SQGSKTLLVLEAPGGRFGT 702
              S+TLL+  A G   G+
Sbjct: 768 HLLSRTLLLAAAEGAAGGS 786



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 66/262 (25%), Positives = 87/262 (33%), Gaps = 37/262 (14%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAA----PSA 280
           PPP   P  A PLL V P      +     R     P +        LA+       PS 
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617

Query: 281 GGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAG--------RSWVGDPGA 332
             S   S   L G   +     E    +  G   GA+ SPP           +W   P  
Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 677

Query: 333 PLTPR---KASCSW-PAPGEASSPGL---------RAGVSAFSCLEEFPGEECSCLAVVV 379
           PL  R    A   W PA G  S+ GL          +   A   L+  P    S      
Sbjct: 678 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737

Query: 380 ASGKGSPSAS-RGSNWGE--------SFSWHCCTAT---AAALLLQRGDSSASGGAAGPP 427
            +G G+ S S + +  GE        S   H  + T   AAA     G     GGA G  
Sbjct: 738 GAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGG 797

Query: 428 LSGSSPSASRGFSRGEPSSLVS 449
           ++G + +A      G  + L+S
Sbjct: 798 VTGGARAALSDAELGRWAELLS 819



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 52/173 (30%), Positives = 64/173 (36%), Gaps = 26/173 (15%)

Query: 205 PGSALRELGVRAGGVGGFLRPPPP--PRPTAAGPLLHVV---------PVTAIFRSGSNH 253
           P  A+      AG   G  RP P   PRP   GP   V          P  A  R  S  
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231

Query: 254 DRLVHLCPLSLTQSACAELAVC-AAPSAGGSP---GKSDAPLGGWLRALRGPR----EPS 305
             L      SL+ SA    +   + PSA G+P        P    L+ALR P+       
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291

Query: 306 SAHTLG----APLGASPSPPAGRSWVGDPGAPLTPRKAS--CSWPAPGEASSP 352
           +A  LG    +PL A+PSP A       P  P TP  +S  C    P   + P
Sbjct: 292 AAPALGPLSSSPL-ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 106/439 (24%), Positives = 147/439 (33%), Gaps = 71/439 (16%)

Query: 276 AAPSAGGSPGKSDAPLGGWLRALRGPREPSS--AHTLGAPLGASPSPPAGRSWVGDPGAP 333
           A PS   SP  S  PL     A   P+ P++   H L AP    PSPP    +      P
Sbjct: 368 APPSPPASPPLS--PL-----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420

Query: 334 LTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSN 393
           ++P     S   P  A+ P           L+  P           AS   SPSA+    
Sbjct: 421 VSPSATPPSQAPPSLAAPP-----------LQVPPSPP--------ASPPMSPSATPPPQ 461

Query: 394 WGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSG--SSPSASRGFSRGEPSSLVSVC 451
                +       A  L L +    A    A PPL    S P++  G +   PS+ + + 
Sbjct: 462 APPPLA-------APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514

Query: 452 FRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALA-----GAPM 506
                  +  PVLAA   +   S   S +     +  +    +   GP L      G P 
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574

Query: 507 GGARERSNTRVIPRL--QSASERLLPSR-GGVAEGCAWDSAYSAPGPVPRHTCGSGVARL 563
             +R  S+T   P L   S+S    P    G   G    +A S P       C       
Sbjct: 575 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 634

Query: 564 EPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANP 623
            P  P       G P   P  +  G   GL                  EG    P  A P
Sbjct: 635 GPAPPLAFRGAPGAPLPWPPATGPGSADGL------------CTIYETEG----PESATP 678

Query: 624 PMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQRNRLRVTHPPESAPGEVRMNQIC 683
             GA  L   P  G + G    G G  A++R P+ A+   L +        G ++ + + 
Sbjct: 679 APGA--LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL--------GALQASVVQ 728

Query: 684 SQGSKTLLVLEAPGGRFGT 702
              S+TLL+  A G   G+
Sbjct: 729 HLLSRTLLLAAAEGAAGGS 747



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 66/262 (25%), Positives = 87/262 (33%), Gaps = 37/262 (14%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAA----PSA 280
           PPP   P  A PLL V P      +     R     P +        LA+       PS 
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578

Query: 281 GGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAG--------RSWVGDPGA 332
             S   S   L G   +     E    +  G   GA+ SPP           +W   P  
Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638

Query: 333 PLTPR---KASCSW-PAPGEASSPGL---------RAGVSAFSCLEEFPGEECSCLAVVV 379
           PL  R    A   W PA G  S+ GL          +   A   L+  P    S      
Sbjct: 639 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698

Query: 380 ASGKGSPSAS-RGSNWGE--------SFSWHCCTAT---AAALLLQRGDSSASGGAAGPP 427
            +G G+ S S + +  GE        S   H  + T   AAA     G     GGA G  
Sbjct: 699 GAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGG 758

Query: 428 LSGSSPSASRGFSRGEPSSLVS 449
           ++G + +A      G  + L+S
Sbjct: 759 VTGGARAALSDAELGRWAELLS 780


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 42/155 (27%), Positives = 60/155 (38%), Gaps = 20/155 (12%)

Query: 299 RGPREPSSAHTLGAPLGASPSPPAGRSW-----VGDPGAPLTP-----RKASCSWPAPGE 348
           +GP      +  G+P   +P PP G  W      G P  P  P     R  S S P P E
Sbjct: 667 QGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTE 726

Query: 349 ASSPGLRAG-----VSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCC 403
             + G   G     + +++ L   PG      A+V  S   +P+ +RG+   +SF+    
Sbjct: 727 GDAEGEAEGPVGSTLGSYATLTRRPGRS----ALVRTSPSVTPTPARGTPRSQSFALRAR 782

Query: 404 TATAAALLLQRGDSSASGGAAGPPLSGSSPSASRG 438
                    +R  SS SG +  PP    SP    G
Sbjct: 783 RKGPPPPPPKR-LSSVSGPSPEPPPLDESPGPKEG 816



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 49/172 (28%), Positives = 62/172 (36%), Gaps = 6/172 (3%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCP--LSLTQSACAELAVCAAPSAGG 282
           PP PPRP      L     T     G     +        +LT+       V  +PS   
Sbjct: 706 PPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTP 765

Query: 283 SPGKSDAPLGGW-LRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASC 341
           +P +       + LRA R    P     L +  G SP PP      G       PR+ + 
Sbjct: 766 TPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTL 825

Query: 342 SWPA-PGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGS 392
           S PA P E   P   AG  A    EE PG E        +SG+G P A  G+
Sbjct: 826 SEPAGPSEPPGPPAPAG-PASDTEEEEPGPE-GTPPSRGSSGEGLPFAEEGN 875


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 42/155 (27%), Positives = 60/155 (38%), Gaps = 20/155 (12%)

Query: 299 RGPREPSSAHTLGAPLGASPSPPAGRSW-----VGDPGAPLTP-----RKASCSWPAPGE 348
           +GP      +  G+P   +P PP G  W      G P  P  P     R  S S P P E
Sbjct: 749 QGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTE 808

Query: 349 ASSPGLRAG-----VSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCC 403
             + G   G     + +++ L   PG      A+V  S   +P+ +RG+   +SF+    
Sbjct: 809 GDAEGEAEGPVGSTLGSYATLTRRPGRS----ALVRTSPSVTPTPARGTPRSQSFALRAR 864

Query: 404 TATAAALLLQRGDSSASGGAAGPPLSGSSPSASRG 438
                    +R  SS SG +  PP    SP    G
Sbjct: 865 RKGPPPPPPKR-LSSVSGPSPEPPPLDESPGPKEG 898



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 49/172 (28%), Positives = 62/172 (36%), Gaps = 6/172 (3%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCP--LSLTQSACAELAVCAAPSAGG 282
           PP PPRP      L     T     G     +        +LT+       V  +PS   
Sbjct: 788 PPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTP 847

Query: 283 SPGKSDAPLGGW-LRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASC 341
           +P +       + LRA R    P     L +  G SP PP      G       PR+ + 
Sbjct: 848 TPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTL 907

Query: 342 SWPA-PGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGS 392
           S PA P E   P   AG  A    EE PG E        +SG+G P A  G+
Sbjct: 908 SEPAGPSEPPGPPAPAG-PASDTEEEEPGPE-GTPPSRGSSGEGLPFAEEGN 957


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/167 (25%), Positives = 58/167 (34%), Gaps = 14/167 (8%)

Query: 492 GGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCAWDSAYSAPGPV 551
           GG+K  GP   G P G   +  N     R      +  P +GG              GP 
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 205

Query: 552 PRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRR 611
           P+          +PQGP    +  GPP     +SQ    P     PG  +        + 
Sbjct: 206 PQ-------GGNKPQGPPPPGKPQGPPPQGDNKSQSARSP-----PGKPQGPPPQGGNQP 253

Query: 612 EGAQNKPIKAN--PPMGAVALRGLPEWGLATGAPFRGRGGSAATREP 656
           +G    P K    PP G    +G P  G   G P +G   S ++R P
Sbjct: 254 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 43/167 (25%), Positives = 59/167 (35%), Gaps = 15/167 (8%)

Query: 492 GGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCAWDSAYSAPGPV 551
           GG+K  GP   G P G   +   +R  PR      +  P +GG              GP 
Sbjct: 85  GGNKPQGPPPPGKPQGPPPQGDKSR-SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 143

Query: 552 PRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRR 611
           P+          +PQGP    +  GPP     +S+    P     PG  +        + 
Sbjct: 144 PQ-------GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP-----PGKPQGPPPQGGNQP 191

Query: 612 EGAQNKPIKAN--PPMGAVALRGLPEWGLATGAPFRGRGGSAATREP 656
           +G    P K    PP G    +G P  G   G P +G   S + R P
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 52/215 (24%), Positives = 69/215 (32%), Gaps = 19/215 (8%)

Query: 492 GGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCAWDSAYSAPGPV 551
           GG+K  GP   G P G   +  N     R      +  P +GG              GP 
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267

Query: 552 PRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRR 611
           P+          +PQGP    +  GPP     +S+    P     PG  +        + 
Sbjct: 268 PQ-------GGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP-----PGKPQGPPPQGGNQP 315

Query: 612 EGAQNKPIKAN--PPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQS-----AQRNRL 664
           +G    P K    PP G    +G P  G   G P +G   S + R P        Q+   
Sbjct: 316 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGN 375

Query: 665 RVTHPPESAPGEVRMNQICSQGSKTLLVLEAPGGR 699
               PP  A G  +  Q    G          GGR
Sbjct: 376 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGR 410



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 37/158 (23%), Positives = 52/158 (32%), Gaps = 15/158 (9%)

Query: 501 LAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCAWDSAYSAPGPVPRHTCGSGV 560
           +AG P G   +  N    P       +  P +GG              GP P+       
Sbjct: 32  IAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ------- 84

Query: 561 ARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIK 620
              +PQGP    +  GPP    +       PG    P  +         + +G    P K
Sbjct: 85  GGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG------GNQPQGPPPPPGK 138

Query: 621 AN--PPMGAVALRGLPEWGLATGAPFRGRGGSAATREP 656
               PP G    +G P  G   G P +G   S ++R P
Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 61/220 (27%), Positives = 76/220 (34%), Gaps = 56/220 (25%)

Query: 211 ELGVRAGGVGGFLRPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACA 270
           ELG R   VG F  PPPPP+ T+A                      +     +   S C 
Sbjct: 706 ELGQR---VGLFPPPPPPPQVTSA----------------------IATLQQAAAMSFCP 740

Query: 271 ELA-VCAAPSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGD 329
           ++A     P A GSP     P  G   A   P  P  A   GAP  ASP  P    + G 
Sbjct: 741 QVARPLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAP--ASPRAPRTSPYGGL 798

Query: 330 PGAPLT----PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGS 385
           P APL     P +       P  AS P L  G          PG   S      ++ +  
Sbjct: 799 PAAPLAGPALPARRLSRASRPLSASQPSLPHGA---------PGPAASTRPASSSTPRLG 849

Query: 386 PSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAG 425
           P+ +               A AAA    R DS++ G A G
Sbjct: 850 PTPA---------------ARAAAPSPDRRDSASPGAAGG 874



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 35/125 (28%), Positives = 44/125 (35%), Gaps = 35/125 (28%)

Query: 560 VARLEPQGPAHLCEGAGPP-----------ANDPQRSQEGGKPGLLISPGAKRLASSARA 608
           + R  P GPA      GPP              P+ S  GG P       A  LA  A  
Sbjct: 757 LVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLP-------AAPLAGPALP 809

Query: 609 RRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQRNRLRVTH 668
            RR    ++P+ A+ P             L  GAP     G AA+  P S+   RL  T 
Sbjct: 810 ARRLSRASRPLSASQP------------SLPHGAP-----GPAASTRPASSSTPRLGPTP 852

Query: 669 PPESA 673
              +A
Sbjct: 853 AARAA 857


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/248 (27%), Positives = 93/248 (37%), Gaps = 44/248 (17%)

Query: 419 ASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVC----FRGKED-------EEKKPVLAAF 467
           A  G   PPL G     +RG     P  +V +       G++D       E   P LA  
Sbjct: 210 AGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLA-- 267

Query: 468 SSRTVRSHLG-STSSTCNMKTLSKLGGSKHLG-PAL-AGAPMGGARERSNTRVIPRLQSA 524
            S+T  + L  S  + CN       GG+  +G PAL A A  GGA+E +      RL   
Sbjct: 268 ESKTKNAALQPSVLTMCN-------GGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRR 320

Query: 525 SERLLPSRGGVAEGCAWDSAYSAPGPVPRHTCGSGVARL-EPQGPAH------------- 570
           +E LLP             A     P P     +GV  +   QG  H             
Sbjct: 321 TETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEA 380

Query: 571 LCEGAGP-----PANDPQ-RSQEGGKPGLL-ISPGAKRLASSARARRREGAQNKPIKANP 623
             E  GP      A D + R +E G+PG+L   PG+ R        R + +  + +K  P
Sbjct: 381 FDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPP 440

Query: 624 PMGAVALR 631
           P  A  +R
Sbjct: 441 PADAPTVR 448



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 69/282 (24%), Positives = 99/282 (35%), Gaps = 37/282 (13%)

Query: 278  PSAGG-SPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTP 336
            P AGG    KS   LG +  A  G  EP +          +  P  G ++  D G P +P
Sbjct: 2487 PGAGGWQEPKSLLSLGSYPPAA-GSSEPKAPWPKATDGDLAQEPGPGLTFE-DSGNPKSP 2544

Query: 337  RKASCSWPAPGEA------SSPGLRAGVSAFSCLEEFPGEE----------------CSC 374
             KA        E+      SS    +  S+ S   E  GEE                CS 
Sbjct: 2545 DKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSA 2604

Query: 375  LAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPS 434
             +   AS   S S+S  S+   S S    ++++++       SS+S  ++    S SS S
Sbjct: 2605 ASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS-----SSSSSSSSSSSSSSSSSSSS 2659

Query: 435  ASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGS 494
            +S   S    SS          D+E  P   A  S        +T      K   K   S
Sbjct: 2660 SSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT------KQAGKARPS 2713

Query: 495  KHLGPALAGAPMGGARERSNTRVI-PRLQSASERLLPSRGGV 535
             H       AP   A     T+ + P+ Q+ ++     R GV
Sbjct: 2714 AHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGV 2755


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 109/465 (23%), Positives = 149/465 (32%), Gaps = 98/465 (21%)

Query: 224 RPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLV-----------------HLCPLSLTQ 266
           +PPPPP P  A  L H +     + S  +   L                     P   T 
Sbjct: 299 QPPPPPPPAHA--LQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA 356

Query: 267 SACAELAVCAAPSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSW 326
            A        A   GG+ G      GG+   ++ P   +     GA  G +  PP  RS 
Sbjct: 357 GASGRATGPEAAGGGGAGGGG----GGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRST 412

Query: 327 -------VGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVV 379
                  +G P A     KAS +  A G+A SPG   G+                     
Sbjct: 413 ATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLL-------------------- 452

Query: 380 ASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSASRGF 439
                 P A     +G+ F        + A        S SGG   PP SG  P      
Sbjct: 453 -----GPQA-----YGQGFGGGQAQDLSKA-------PSYSGGPPQPP-SGPPPPGLATC 494

Query: 440 SRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGP 499
               P  L    +      E  P  AA S     +    + ST +   LS  GG    GP
Sbjct: 495 QSYSPDQLQGQLY--GVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGG--WGP 550

Query: 500 ALAGAPMGGARERSNTRVIPRLQSASERLLP-------SRGGVAEGCAWDSAYSAPGPVP 552
               + +GG  E S + +I  LQS      P       + G         + + AP    
Sbjct: 551 ----SSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAG 606

Query: 553 RHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRRE 612
            +  G+G  + +  G   L    GPPA +    +E     LL +P   R + +      +
Sbjct: 607 SYAAGAGGYKGKGDGSELLAGPGGPPA-ERTEDEEFLIQHLLQAPSPPRTSGADGLVGED 665

Query: 613 GAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQ 657
           GA            A A +GL   G A G P  G     A  +PQ
Sbjct: 666 GA------------ADASKGLGGSGGAGGPP--GTPYELAKEDPQ 696



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 123/549 (22%), Positives = 167/549 (30%), Gaps = 118/549 (21%)

Query: 217 GGVGGFLRPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCA 276
           G   G    PPPPR TA      +    A + +G                          
Sbjct: 397 GAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGK------------------------- 431

Query: 277 APSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTP 336
           A  AGG+ G++ +P  G  + L GP+        G     S +P         P  P  P
Sbjct: 432 ASGAGGAGGQAYSP--GQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPP 489

Query: 337 RKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVAS-------GKGSPSAS 389
             A+C   +P +    G   GV      E +PG       +  AS       G     + 
Sbjct: 490 GLATCQSYSPDQLQ--GQLYGVQG----EPYPGPAAHSQGLPTASPSLSYSTGHSPALSG 543

Query: 390 RGSNW--------GESFSWHCCTATAAALLLQRGDSSASGGAAG--------------PP 427
            G  W        GE+   H      +     R     S GA G              PP
Sbjct: 544 HGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPP 603

Query: 428 LSGSSPSASRGF-SRGEPSSLVS----VCFRGKEDEE--KKPVLAAFSSRTVRSHLGSTS 480
            +GS  + + G+  +G+ S L++          EDEE   + +L A S        G   
Sbjct: 604 GAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVG 663

Query: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARE-------RSNTRVIPRLQSASERLL---- 529
                     LGGS   G    G P   A+E       +S  R    L   +   L    
Sbjct: 664 EDGAADASKGLGGSGGAG-GPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGL 722

Query: 530 ---------PSRGG-VAEGCAWDSAYSAPG------------PVPRHTCGSGVARLEPQG 567
                    P RGG   EG A    +   G            P P  T  S     +P  
Sbjct: 723 GRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQS----TQPTP 778

Query: 568 PAHLCEGAGP------PANDPQRSQEGGKPGLLISPGAKRL-ASSARARRREGAQNKPIK 620
              L E  GP      P   PQ            SP A ++         R+GA   P  
Sbjct: 779 HGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPP 838

Query: 621 ANPPMGAVALR---GLPEWGLATGAPFRGRGGSAATREPQSAQRNRLRVTHPPESAPGEV 677
             PP   + L+    L   GL   AP   R     + +P  A +  L    P   APG+ 
Sbjct: 839 PPPPPPPMPLQLEAHLRSHGLEPAAP-SPRLRPEESLDPPGAMQELLGALEPLPPAPGDT 897

Query: 678 RMNQICSQG 686
            +    S+G
Sbjct: 898 GVGPPNSEG 906



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 38/134 (28%), Positives = 48/134 (35%), Gaps = 15/134 (11%)

Query: 315 GASPSPPAGRSWVGDPGAPLT--PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFP--GE 370
           GA+P PP     +      +    R AS   P P     P   A     SC   +P  G 
Sbjct: 270 GAAPGPPPPERALPRQDTVIKHYQRPASAQPPPP----PPPAHALQHYLSCGGSYPSMGH 325

Query: 371 ECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSG 430
             +     +  G+ SP A   S  G S       ATA A     G  +A GG AG    G
Sbjct: 326 RANLACSPLGGGEPSPGAGEPSKAGPS------GATAGASGRATGPEAAGGGGAGGGGGG 379

Query: 431 SSP-SASRGFSRGE 443
             P   S G+  G+
Sbjct: 380 YRPIIQSPGYKTGK 393


>gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo
           sapiens]
          Length = 630

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 119/467 (25%), Positives = 160/467 (34%), Gaps = 121/467 (25%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSG--SNHDRLVHLCPLSLTQSACAELAVCAAPSAGG 282
           P P P P + G ++    V    R    S  D ++H    SL++S              G
Sbjct: 177 PLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSES--------------G 222

Query: 283 SPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPS-------PPAG--------RSWV 327
           +   ++ P G +  A R P  P +   L A  G SP        PP+         R+ V
Sbjct: 223 ASHDNEEPHGCFSLAER-PSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSV 281

Query: 328 GDPGAPLT--PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGS 385
             P +P    PR AS S+      ++P L  G     C  E  G      +    S  G 
Sbjct: 282 ASPTSPTRSLPRSAS-SFEGRSVPATPVLTRGAGPQLCKPE--GLHSRQWSGSQDSQMGF 338

Query: 386 PSASRGSNWGESFSWHCCTATAA-ALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEP 444
           P A   S+    F      + ++ ALL+ R    A+GG AG P +  +PSAS     G P
Sbjct: 339 PRADPASDRASLFVARTRRSNSSEALLVDR----AAGGGAGSPPAPLAPSAS-----GPP 389

Query: 445 SSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGA 504
                VC   +   E+     AFSSR           T       +        PA  GA
Sbjct: 390 -----VCKSSEVLYERPQPTPAFSSR-----------TAGPPDPPRAARPSSAAPASRGA 433

Query: 505 PMGGARERSNTRVIP-----RLQSASERLLPSRGGVAEGCAWDSAYSA------------ 547
           P          R+ P      L  + +R LP  GG   G  W     A            
Sbjct: 434 P----------RLPPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPGPLSRRDG 480

Query: 548 -----PGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGK---PGLLISPGA 599
                PGP P +   S    L  + P H       P   P  + EG +     LL  P  
Sbjct: 481 LLTMLPGPPPVYAADSNSPLLRTKDP-HTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPP 539

Query: 600 KRLASSARARRREGAQNKPIKANPPMGAVALRGLPEW-----GLATG 641
            R+ S   A  R G +N           +AL GL +W     GLA G
Sbjct: 540 TRIPS---AGERSGHKN-----------LALEGLRDWYIRNSGLAAG 572


>gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo
           sapiens]
          Length = 618

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 119/467 (25%), Positives = 160/467 (34%), Gaps = 121/467 (25%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSG--SNHDRLVHLCPLSLTQSACAELAVCAAPSAGG 282
           P P P P + G ++    V    R    S  D ++H    SL++S              G
Sbjct: 165 PLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSES--------------G 210

Query: 283 SPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPS-------PPAG--------RSWV 327
           +   ++ P G +  A R P  P +   L A  G SP        PP+         R+ V
Sbjct: 211 ASHDNEEPHGCFSLAER-PSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSV 269

Query: 328 GDPGAPLT--PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGS 385
             P +P    PR AS S+      ++P L  G     C  E  G      +    S  G 
Sbjct: 270 ASPTSPTRSLPRSAS-SFEGRSVPATPVLTRGAGPQLCKPE--GLHSRQWSGSQDSQMGF 326

Query: 386 PSASRGSNWGESFSWHCCTATAA-ALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEP 444
           P A   S+    F      + ++ ALL+ R    A+GG AG P +  +PSAS     G P
Sbjct: 327 PRADPASDRASLFVARTRRSNSSEALLVDR----AAGGGAGSPPAPLAPSAS-----GPP 377

Query: 445 SSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGA 504
                VC   +   E+     AFSSR           T       +        PA  GA
Sbjct: 378 -----VCKSSEVLYERPQPTPAFSSR-----------TAGPPDPPRAARPSSAAPASRGA 421

Query: 505 PMGGARERSNTRVIP-----RLQSASERLLPSRGGVAEGCAWDSAYSA------------ 547
           P          R+ P      L  + +R LP  GG   G  W     A            
Sbjct: 422 P----------RLPPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPGPLSRRDG 468

Query: 548 -----PGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGK---PGLLISPGA 599
                PGP P +   S    L  + P H       P   P  + EG +     LL  P  
Sbjct: 469 LLTMLPGPPPVYAADSNSPLLRTKDP-HTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPP 527

Query: 600 KRLASSARARRREGAQNKPIKANPPMGAVALRGLPEW-----GLATG 641
            R+ S   A  R G +N           +AL GL +W     GLA G
Sbjct: 528 TRIPS---AGERSGHKN-----------LALEGLRDWYIRNSGLAAG 560


>gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo
           sapiens]
          Length = 649

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 119/467 (25%), Positives = 160/467 (34%), Gaps = 121/467 (25%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSG--SNHDRLVHLCPLSLTQSACAELAVCAAPSAGG 282
           P P P P + G ++    V    R    S  D ++H    SL++S              G
Sbjct: 165 PLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSES--------------G 210

Query: 283 SPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPS-------PPAG--------RSWV 327
           +   ++ P G +  A R P  P +   L A  G SP        PP+         R+ V
Sbjct: 211 ASHDNEEPHGCFSLAER-PSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSV 269

Query: 328 GDPGAPLT--PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGS 385
             P +P    PR AS S+      ++P L  G     C  E  G      +    S  G 
Sbjct: 270 ASPTSPTRSLPRSAS-SFEGRSVPATPVLTRGAGPQLCKPE--GLHSRQWSGSQDSQMGF 326

Query: 386 PSASRGSNWGESFSWHCCTATAA-ALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEP 444
           P A   S+    F      + ++ ALL+ R    A+GG AG P +  +PSAS     G P
Sbjct: 327 PRADPASDRASLFVARTRRSNSSEALLVDR----AAGGGAGSPPAPLAPSAS-----GPP 377

Query: 445 SSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGA 504
                VC   +   E+     AFSSR           T       +        PA  GA
Sbjct: 378 -----VCKSSEVLYERPQPTPAFSSR-----------TAGPPDPPRAARPSSAAPASRGA 421

Query: 505 PMGGARERSNTRVIP-----RLQSASERLLPSRGGVAEGCAWDSAYSA------------ 547
           P          R+ P      L  + +R LP  GG   G  W     A            
Sbjct: 422 P----------RLPPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPGPLSRRDG 468

Query: 548 -----PGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGK---PGLLISPGA 599
                PGP P +   S    L  + P H       P   P  + EG +     LL  P  
Sbjct: 469 LLTMLPGPPPVYAADSNSPLLRTKDP-HTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPP 527

Query: 600 KRLASSARARRREGAQNKPIKANPPMGAVALRGLPEW-----GLATG 641
            R+ S   A  R G +N           +AL GL +W     GLA G
Sbjct: 528 TRIPS---AGERSGHKN-----------LALEGLRDWYIRNSGLAAG 560


>gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 119/467 (25%), Positives = 160/467 (34%), Gaps = 121/467 (25%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSG--SNHDRLVHLCPLSLTQSACAELAVCAAPSAGG 282
           P P P P + G ++    V    R    S  D ++H    SL++S              G
Sbjct: 177 PLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSES--------------G 222

Query: 283 SPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPS-------PPAG--------RSWV 327
           +   ++ P G +  A R P  P +   L A  G SP        PP+         R+ V
Sbjct: 223 ASHDNEEPHGCFSLAER-PSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSV 281

Query: 328 GDPGAPLT--PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGS 385
             P +P    PR AS S+      ++P L  G     C  E  G      +    S  G 
Sbjct: 282 ASPTSPTRSLPRSAS-SFEGRSVPATPVLTRGAGPQLCKPE--GLHSRQWSGSQDSQMGF 338

Query: 386 PSASRGSNWGESFSWHCCTATAA-ALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEP 444
           P A   S+    F      + ++ ALL+ R    A+GG AG P +  +PSAS     G P
Sbjct: 339 PRADPASDRASLFVARTRRSNSSEALLVDR----AAGGGAGSPPAPLAPSAS-----GPP 389

Query: 445 SSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGA 504
                VC   +   E+     AFSSR           T       +        PA  GA
Sbjct: 390 -----VCKSSEVLYERPQPTPAFSSR-----------TAGPPDPPRAARPSSAAPASRGA 433

Query: 505 PMGGARERSNTRVIP-----RLQSASERLLPSRGGVAEGCAWDSAYSA------------ 547
           P          R+ P      L  + +R LP  GG   G  W     A            
Sbjct: 434 P----------RLPPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPGPLSRRDG 480

Query: 548 -----PGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGK---PGLLISPGA 599
                PGP P +   S    L  + P H       P   P  + EG +     LL  P  
Sbjct: 481 LLTMLPGPPPVYAADSNSPLLRTKDP-HTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPP 539

Query: 600 KRLASSARARRREGAQNKPIKANPPMGAVALRGLPEW-----GLATG 641
            R+ S   A  R G +N           +AL GL +W     GLA G
Sbjct: 540 TRIPS---AGERSGHKN-----------LALEGLRDWYIRNSGLAAG 572


>gi|239743072 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 837

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 91/355 (25%), Positives = 118/355 (33%), Gaps = 53/355 (14%)

Query: 3   GLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAPLV 62
           GLG  G   G  R           A+   ++R  G      A+T L  A+   G   P+ 
Sbjct: 354 GLGSGGTRRGGRRLGFHGAQTSKGALLATATRAHGHGVPGKAATVLYKALHGRGLSRPVG 413

Query: 63  LGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGI-------------GHPLGWGL 109
             + +  + AA  R      PR  +  LG     D  G+             GH  G  +
Sbjct: 414 RRVHVSDRPAAGGRRAGQHSPRVQVGLLGGGG-SDHGGLLFGAAVVVLRGQHGHLRGGEV 472

Query: 110 --LGGSPGA--AGGRGGHGL--EGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGL 163
             L G P    AGGRG  GL  E     L  R G + G   A  R+   L    G  +G 
Sbjct: 473 AQLEGFPFMLRAGGRGAPGLQAEELGGLLGCRTGWAAGRTLAGPRVRLGLEQLLGRHVGA 532

Query: 164 WARSGGNAPVEGCPRRFHFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFL 223
             R G   P  G           G+  GR       + RV+   AL  +  R  G GG L
Sbjct: 533 GVRGGACGPHRG-----------GIRGGRPLER--ADDRVLLAQALGPVQ-RPRGAGGRL 578

Query: 224 RPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACA--ELAVCAAPSAG 281
           + P P     AGP         I R G + D      P +L +      E         G
Sbjct: 579 QDPWPASLALAGP--------GIARLGCDLDG-----PRALVEGLHGRHEGGPLGGAGGG 625

Query: 282 GSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTP 336
           GS        G  +   R  R PSS          +P  PA  +  G P +P  P
Sbjct: 626 GSGEGQGRGPGSRVSVRRSSRAPSSCRA----ASLAPPRPASATSAGSPTSPAPP 676


>gi|239508718 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 837

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 91/355 (25%), Positives = 118/355 (33%), Gaps = 53/355 (14%)

Query: 3   GLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAPLV 62
           GLG  G   G  R           A+   ++R  G      A+T L  A+   G   P+ 
Sbjct: 354 GLGSGGTRRGGRRLGFHGAQTSKGALLATATRAHGHGVPGKAATVLYKALHGRGLSRPVG 413

Query: 63  LGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGI-------------GHPLGWGL 109
             + +  + AA  R      PR  +  LG     D  G+             GH  G  +
Sbjct: 414 RRVHVSDRPAAGGRRAGQHSPRVQVGLLGGGG-SDHGGLLFGAAVVVLRGQHGHLRGGEV 472

Query: 110 --LGGSPGA--AGGRGGHGL--EGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGL 163
             L G P    AGGRG  GL  E     L  R G + G   A  R+   L    G  +G 
Sbjct: 473 AQLEGFPFMLRAGGRGAPGLQAEELGGLLGCRTGWAAGRTLAGPRVRLGLEQLLGRHVGA 532

Query: 164 WARSGGNAPVEGCPRRFHFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFL 223
             R G   P  G           G+  GR       + RV+   AL  +  R  G GG L
Sbjct: 533 GVRGGACGPHRG-----------GIRGGRPLER--ADDRVLLAQALGPVQ-RPRGAGGRL 578

Query: 224 RPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACA--ELAVCAAPSAG 281
           + P P     AGP         I R G + D      P +L +      E         G
Sbjct: 579 QDPWPASLALAGP--------GIARLGCDLDG-----PRALVEGLHGRHEGGPLGGAGGG 625

Query: 282 GSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTP 336
           GS        G  +   R  R PSS          +P  PA  +  G P +P  P
Sbjct: 626 GSGEGQGRGPGSRVSVRRSSRAPSSCRA----ASLAPPRPASATSAGSPTSPAPP 676


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 98/408 (24%), Positives = 125/408 (30%), Gaps = 64/408 (15%)

Query: 277  APSAGGSPGKSDAPLGGWLRALRGP--REPSSAHTLGAPLGASPSPPAGRSWVGDPGAPL 334
            AP   G+PG S  P       LRG   ++        A    SP P   R   G PG P 
Sbjct: 920  APGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPG 979

Query: 335  TPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPG-EECSCLAVVVASGKGSPS--ASRG 391
             P K       PG   SPGL   +   +   +  G E C+     V   +G+P    S G
Sbjct: 980  PPGKGKDG--EPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG 1037

Query: 392  SNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVC 451
            S            A         GD  + G    P   G    A R  + G P       
Sbjct: 1038 SRGDPGIG----VAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNP------- 1086

Query: 452  FRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAP------ 505
              G+     KP L++  S              N+             P L G P      
Sbjct: 1087 --GERGPPGKPGLSSLLS----------PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134

Query: 506  -MGGARERSNTRVIPRLQSASERLLPSRGGVAEGCAWDSAYSAPGPVPRHTCGSGVARLE 564
             + G   R  T    +   A    LP   G+A          A G V     G    +  
Sbjct: 1135 GVPGKPGREGTE--GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEV-----GQKGDQGH 1187

Query: 565  PQGPAHLCEGAGPPANDPQRSQEG-----GKPGLLISPGAK---------RLASSARARR 610
            P  P  +    GPP N      +G     G PG+  SPG +          L        
Sbjct: 1188 PGVPGFM----GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243

Query: 611  REGAQNKPIKANPPMGAVALRGLPEWGLATGAP-FRGRGGSAATREPQ 657
            +EG   KP     P G     GLP    A G P F+G  G +    P+
Sbjct: 1244 KEGRDGKPGPPGEP-GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPR 1290



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 37/137 (27%), Positives = 44/137 (32%), Gaps = 20/137 (14%)

Query: 218  GVGGFLRPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAA 277
            GV GF+ PP  P P  A  +        I  S           P  L             
Sbjct: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP----------GI 1238

Query: 278  PSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAP-LGASPSPPAGRSWVGDPGAPLTP 336
            P   G  G+   P          P EP  A   G P    +  PP  +   GD GAP  P
Sbjct: 1239 PGEEGKEGRDGKP--------GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAP-GP 1289

Query: 337  RKASCSWPAPGEASSPG 353
            R  S +   PG+   PG
Sbjct: 1290 RGESGAMGLPGQEGLPG 1306



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 29/109 (26%), Positives = 33/109 (30%), Gaps = 23/109 (21%)

Query: 278  PSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAP-LGASPSPPAGRSWVGDPGAPLTP 336
            P   G PGK   P          P EP      G P +     PP G+   GDPG P   
Sbjct: 1371 PGEKGVPGKEGVP--------GKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHK 1422

Query: 337  RKASCSWP--------------APGEASSPGLRAGVSAFSCLEEFPGEE 371
                   P               PG+   PGLR    +   L     EE
Sbjct: 1423 GHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 101/431 (23%), Positives = 128/431 (29%), Gaps = 64/431 (14%)

Query: 272  LAVCAAPSAGGSPGKSDAPLGGWLRALRGPREPSSAH-TLGAPLGASPSPPAGRSWVGDP 330
            + V   P   G PG   +P    L    GP+ P+      G P    P    G S +  P
Sbjct: 1044 IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSP 1103

Query: 331  GAPLTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASR 390
            G      K  C+   PG    PGL  G      +   PG E          G+  P    
Sbjct: 1104 GDINLLAKDVCNDCPPGPPGLPGL-PGFKGDKGVPGKPGRE----GTEGKKGEAGPPGLP 1158

Query: 391  GSNWGESFSWHCCTATAAALLLQRGDSSASG--------------------GAAGPPLSG 430
            G               A   + Q+GD    G                    GAAGPP   
Sbjct: 1159 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 1218

Query: 431  SSPSASRGFSRGEPSSLVSV-CFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLS 489
             SP          PS L  +    GKE  + KP       +     L             
Sbjct: 1219 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG-----ARG 1273

Query: 490  KLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCAWDSAYSAP- 548
              G   H G   +GAP  G R  S    +P      +  LP + G       D+  + P 
Sbjct: 1274 PPGFKGHTGD--SGAP--GPRGESGAMGLP-----GQEGLPGKDG-------DTGPTGPQ 1317

Query: 549  GPV-PRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEG--GKPGLLISPGAKRLASS 605
            GP  PR   G   +   P  P       GP     Q+  +G  G PGL    G +     
Sbjct: 1318 GPQGPRGPPGKNGSPGSPGEP-------GPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE 1370

Query: 606  ARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQRNRLR 665
               +   G +  P K   P G    RG P      G P    GG     +P         
Sbjct: 1371 PGEKGVPGKEGVPGKPGEP-GFKGERGDPGIKGDKGPP----GGKGQPGDPGIPGHKGHT 1425

Query: 666  VTHPPESAPGE 676
                P+  PGE
Sbjct: 1426 GLMGPQGLPGE 1436


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 35/179 (19%)

Query: 278 PSAGGSPGKSDAPLGGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPR 337
           P  GG+  +S APL  +  A  GP+   +A        A PS P G    G  G  L P 
Sbjct: 279 PPVGGAVAQSSAPLPPFPGAATGPQPMMAA--------AQPSQPQG---AGPGGQTLPPT 327

Query: 338 KASCSWPAPGEASSPGLRAGVSAFSCLEEF----------------PGEECSCLAVVVAS 381
             + + PA      PG   G  A    ++F                P  +   L   VA 
Sbjct: 328 NVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVA- 386

Query: 382 GKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSASRGFS 440
           G   PS ++ S+ G + S     ATAA L +  G +++S GA    L G+S   S   +
Sbjct: 387 GLQPPSPAQPSSTGAAAS----PATAATLPVGTGQNASSVGA---QLMGASSQPSEAMA 438


>gi|148886696 surfactant protein A2 [Homo sapiens]
          Length = 248

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 36/106 (33%), Positives = 46/106 (43%), Gaps = 15/106 (14%)

Query: 259 LCPLSLTQ-------SACAELAVCA-APSAGGSPGKSDAPLGGWLRALRGPREPSSAHTL 310
           LCPL+LT        +AC    VC  +P   G+PG    P       ++G  +P     +
Sbjct: 3   LCPLALTLILMAASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKG--DPGPPGPM 60

Query: 311 GAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRA 356
           G P G +P PP      G PGAP  P +      A GE   PGL A
Sbjct: 61  GPP-GETPCPPGNN---GLPGAPGVPGERGEKGEA-GERGPPGLPA 101


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,373,185
Number of Sequences: 37866
Number of extensions: 2265870
Number of successful extensions: 15634
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 570
Number of HSP's that attempted gapping in prelim test: 13320
Number of HSP's gapped (non-prelim): 2912
length of query: 709
length of database: 18,247,518
effective HSP length: 109
effective length of query: 600
effective length of database: 14,120,124
effective search space: 8472074400
effective search space used: 8472074400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.