Search of human proteins with 116295254

Search of human proteins with 116295254

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116295254 heparan sulfate 6-O-sulfotransferase 2 isoform S
[Homo sapiens]
         (605 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116295254 heparan sulfate 6-O-sulfotransferase 2 isoform S [H...  1242   0.0  
gi|116295256 heparan sulfate 6-O-sulfotransferase 2 isoform L [H...  1222   0.0  
gi|239756047 PREDICTED: heparan sulfate 6-O-sulfotransferase 3 [...   521   e-148
gi|45580707 heparan sulfate 6-O-sulfotransferase 3 [Homo sapiens]     521   e-148
gi|148747866 heparan sulfate 6-O-sulfotransferase 1 [Homo sapiens]    501   e-142
gi|110347429 mediator complex subunit 12 [Homo sapiens]                39   0.014
gi|221139761 zinc finger protein 853 [Homo sapiens]                    38   0.024
gi|226246533 TOX high mobility group box family member 3 isoform...    37   0.040
gi|226054295 TOX high mobility group box family member 3 isoform...    37   0.040
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  37   0.040
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          37   0.069
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    36   0.12 
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    36   0.12 
gi|30911103 pygopus homolog 1 [Homo sapiens]                           36   0.12 
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   34   0.34 
gi|22538413 forkhead box P2 isoform III [Homo sapiens]                 34   0.34 
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 34   0.34 
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         34   0.34 
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    34   0.44 
gi|44890059 involucrin [Homo sapiens]                                  33   0.58 
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [...    33   0.58 
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    33   0.58 
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    33   0.58 
gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled...    33   0.76 
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                33   0.99 
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    33   0.99 
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    33   0.99 
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    33   0.99 
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    33   0.99 
gi|45505178 cancer antigen 1 [Homo sapiens]                            33   0.99 

>gi|116295254 heparan sulfate 6-O-sulfotransferase 2 isoform S [Homo
           sapiens]
          Length = 605

 Score = 1242 bits (3213), Expect = 0.0
 Identities = 605/605 (100%), Positives = 605/605 (100%)

Query: 1   MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSH 60
           MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSH
Sbjct: 1   MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSH 60

Query: 61  GFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLA 120
           GFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLA
Sbjct: 61  GFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLA 120

Query: 121 ALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL 180
           ALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL
Sbjct: 121 ALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL 180

Query: 181 LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGT 240
           LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGT
Sbjct: 181 LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGT 240

Query: 241 TFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCV 300
           TFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCV
Sbjct: 241 TFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCV 300

Query: 301 PSVVDGKRDARLRPSRNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEE 360
           PSVVDGKRDARLRPSRNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEE
Sbjct: 301 PSVVDGKRDARLRPSRNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEE 360

Query: 361 LPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLES 420
           LPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLES
Sbjct: 361 LPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLES 420

Query: 421 AKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGL 480
           AKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGL
Sbjct: 421 AKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGL 480

Query: 481 NFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQN 540
           NFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQN
Sbjct: 481 NFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQN 540

Query: 541 PNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTNDYIGS 600
           PNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTNDYIGS
Sbjct: 541 PNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTNDYIGS 600

Query: 601 VEKWR 605
           VEKWR
Sbjct: 601 VEKWR 605


>gi|116295256 heparan sulfate 6-O-sulfotransferase 2 isoform L [Homo
           sapiens]
          Length = 645

 Score = 1222 bits (3162), Expect = 0.0
 Identities = 605/645 (93%), Positives = 605/645 (93%), Gaps = 40/645 (6%)

Query: 1   MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSH 60
           MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSH
Sbjct: 1   MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSH 60

Query: 61  GFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLA 120
           GFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLA
Sbjct: 61  GFHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLA 120

Query: 121 ALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL 180
           ALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL
Sbjct: 121 ALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL 180

Query: 181 LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGT 240
           LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGT
Sbjct: 181 LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGT 240

Query: 241 TFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCV 300
           TFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCV
Sbjct: 241 TFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCV 300

Query: 301 PSVVDGKRDARLRPSR----------------------------------------NFHY 320
           PSVVDGKRDARLRPSR                                        NFHY
Sbjct: 301 PSVVDGKRDARLRPSRWRIFQILDAASKDKRGSPNTNAGANSPSSTKTRNTSKSGKNFHY 360

Query: 321 ITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMD 380
           ITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMD
Sbjct: 361 ITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMD 420

Query: 381 CPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKT 440
           CPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKT
Sbjct: 421 CPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKT 480

Query: 441 QYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQ 500
           QYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQ
Sbjct: 481 QYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQ 540

Query: 501 FMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQN 560
           FMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQN
Sbjct: 541 FMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQN 600

Query: 561 LMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTNDYIGSVEKWR 605
           LMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTNDYIGSVEKWR
Sbjct: 601 LMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTNDYIGSVEKWR 645


>gi|239756047 PREDICTED: heparan sulfate 6-O-sulfotransferase 3
           [Homo sapiens]
          Length = 471

 Score =  521 bits (1342), Expect = e-148
 Identities = 242/330 (73%), Positives = 285/330 (86%), Gaps = 1/330 (0%)

Query: 191 PDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNI 250
           PDP   E+ S  RFVPR+NF+  DL R VDF+IKG D+IVFLHIQKTGGTTFGRHLV+NI
Sbjct: 110 PDPEAPENGSLPRFVPRFNFSLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNI 169

Query: 251 QLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDA 310
           +LEQPC C+ GQKKCTCHRPGK+ETWLFSRFSTGWSCGLHADWTELT+CVP++++ K   
Sbjct: 170 RLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCP 229

Query: 311 RLRP-SRNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDD 369
           R    +RNF+YIT+LRDPVSRYLSEW+HVQRGATWK SLH+CDGR PT +ELP+CY GDD
Sbjct: 230 RNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDD 289

Query: 370 WSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMA 429
           WSG  L+EFMDC YNLANNRQVRML+DL+LVGCYNL+ M E +RN +LL+SAK+NLK+MA
Sbjct: 290 WSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMA 349

Query: 430 FFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYS 489
           FFGLTEFQRKTQ+LFE+TFN+ FISPFTQ+N TRAS+VEINE  ++RIE LNFLDM+LY 
Sbjct: 350 FFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARQRIEDLNFLDMQLYE 409

Query: 490 YAKDLFLQRYQFMRQKEHQEARRKRQEQRK 519
           YAKDLF QRY   +Q EHQ  R+KR+E+R+
Sbjct: 410 YAKDLFQQRYHHTKQLEHQRDRQKRREERR 439



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 16/28 (57%), Positives = 19/28 (67%)

Query: 147 MDEKSNKLLLALVMLFLFAVIVLQYVCP 174
           MDE+ NK LL  V+  LF VI+ QYV P
Sbjct: 1   MDERFNKWLLTPVLTLLFVVIMYQYVSP 28


>gi|45580707 heparan sulfate 6-O-sulfotransferase 3 [Homo sapiens]
          Length = 471

 Score =  521 bits (1342), Expect = e-148
 Identities = 242/330 (73%), Positives = 285/330 (86%), Gaps = 1/330 (0%)

Query: 191 PDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNI 250
           PDP   E+ S  RFVPR+NF+  DL R VDF+IKG D+IVFLHIQKTGGTTFGRHLV+NI
Sbjct: 110 PDPEAPENGSLPRFVPRFNFSLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNI 169

Query: 251 QLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDA 310
           +LEQPC C+ GQKKCTCHRPGK+ETWLFSRFSTGWSCGLHADWTELT+CVP++++ K   
Sbjct: 170 RLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCP 229

Query: 311 RLRP-SRNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDD 369
           R    +RNF+YIT+LRDPVSRYLSEW+HVQRGATWK SLH+CDGR PT +ELP+CY GDD
Sbjct: 230 RNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDD 289

Query: 370 WSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMA 429
           WSG  L+EFMDC YNLANNRQVRML+DL+LVGCYNL+ M E +RN +LL+SAK+NLK+MA
Sbjct: 290 WSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMA 349

Query: 430 FFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYS 489
           FFGLTEFQRKTQ+LFE+TFN+ FISPFTQ+N TRAS+VEINE  ++RIE LNFLDM+LY 
Sbjct: 350 FFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARQRIEDLNFLDMQLYE 409

Query: 490 YAKDLFLQRYQFMRQKEHQEARRKRQEQRK 519
           YAKDLF QRY   +Q EHQ  R+KR+E+R+
Sbjct: 410 YAKDLFQQRYHHTKQLEHQRDRQKRREERR 439



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 16/28 (57%), Positives = 19/28 (67%)

Query: 147 MDEKSNKLLLALVMLFLFAVIVLQYVCP 174
           MDE+ NK LL  V+  LF VI+ QYV P
Sbjct: 1   MDERFNKWLLTPVLTLLFVVIMYQYVSP 28


>gi|148747866 heparan sulfate 6-O-sulfotransferase 1 [Homo sapiens]
          Length = 411

 Score =  501 bits (1291), Expect = e-142
 Identities = 242/377 (64%), Positives = 290/377 (76%), Gaps = 14/377 (3%)

Query: 147 MDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSS-----PVPDPYRSEDESS 201
           M E+++K +L +     F +I+ QY  PG        +A        P PDP+       
Sbjct: 11  MVERASKFVLVVAGSVCFMLILYQYAGPGLSLGAPGGRAPPDDLDLFPTPDPH------- 63

Query: 202 ARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVG 261
             +  +Y F   +L R + FD+KGDD+IVFLHIQKTGGTTFGRHLV+N++LE PC+CR G
Sbjct: 64  --YEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPG 121

Query: 262 QKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRNFHYI 321
           QKKCTC+RP +RETWLFSRFSTGWSCGLHADWTELT+CVP V+D +  A LR  R F+YI
Sbjct: 122 QKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDSAALRTPRKFYYI 181

Query: 322 TILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDC 381
           T+LRDPVSRYLSEWRHVQRGATWK SLH+CDGR PT EELP CY G DWSGC L+EFMDC
Sbjct: 182 TLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDC 241

Query: 382 PYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQ 441
           PYNLANNRQVRML+DL+LVGCYNLS +PE +R ++LLESAK NL+ MAFFGLTEFQRKTQ
Sbjct: 242 PYNLANNRQVRMLADLSLVGCYNLSFIPEGKRAQLLLESAKKNLRGMAFFGLTEFQRKTQ 301

Query: 442 YLFEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQF 501
           YLFE+TFN+ FI PF QYN+TRA  VE++E+  +RIE LN LDM+LY YAKDLF QRYQ+
Sbjct: 302 YLFERTFNLKFIRPFMQYNSTRAGGVEVDEDTIRRIEELNDLDMQLYDYAKDLFQQRYQY 361

Query: 502 MRQKEHQEARRKRQEQR 518
            RQ E +E R + +E+R
Sbjct: 362 KRQLERREQRLRSREER 378


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 37/165 (22%), Positives = 68/165 (41%), Gaps = 2/165 (1%)

Query: 432  GLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRA-SSVEINEEIQKRIEGLNFLDMELYSY 490
            GLT  QR +    ++T  ++ ++P +         S  I  E Q++ +       +    
Sbjct: 2009 GLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQ 2068

Query: 491  AKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPN 550
             +    Q+Y  +RQ++ Q+  R++Q+Q++  + +  Q   Q Q Q Q     Q Q   P 
Sbjct: 2069 QQQQQQQQYH-IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPP 2127

Query: 551  PNANQNLTQNLMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTN 595
                Q+  Q   Q L Q+  Q++     +Q   +  N      TN
Sbjct: 2128 QPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTN 2172


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 38.1 bits (87), Expect = 0.024
 Identities = 28/122 (22%), Positives = 55/122 (45%), Gaps = 10/122 (8%)

Query: 458 QYNTTRASSVEI---NEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKR 514
           Q  T +A   ++    E++Q++++    L  +     +   LQ+ + ++Q++ Q+ + + 
Sbjct: 176 QLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQL 235

Query: 515 QEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKEN 574
           Q+Q++ L         Q QGQ Q Q   Q Q+Q       Q   Q   Q L Q   Q + 
Sbjct: 236 QQQQQLLL-------LQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288

Query: 575 RE 576
           ++
Sbjct: 289 QQ 290



 Score = 29.6 bits (65), Expect = 8.4
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 7/89 (7%)

Query: 500 QFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQ 559
           Q M Q++  + ++ +++QR   +   LQT      Q Q Q   Q Q Q       Q L Q
Sbjct: 151 QLMHQQQQLQPQQVQEQQRLQQQQEQLQTQ-----QAQEQQVLQQQEQLQQQVQEQQLLQ 205

Query: 560 NLMQNLTQS--LSQKENRESPKQNSGKEQ 586
              + L Q   L Q+E  +  +    +EQ
Sbjct: 206 QQQEQLQQQQLLQQQEQLQQQQFQQQQEQ 234


>gi|226246533 TOX high mobility group box family member 3 isoform 2
           [Homo sapiens]
          Length = 571

 Score = 37.4 bits (85), Expect = 0.040
 Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 464 ASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKG 523
           A S +++  +Q +   +     +     +   +Q+ Q  + + HQ+ +++ Q+Q      
Sbjct: 422 APSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHF---Q 478

Query: 524 RLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRESPKQNS 582
             +Q H Q Q Q   Q  NQ Q Q       Q L Q L     Q + Q +++ SP+Q+S
Sbjct: 479 HHMQQHLQQQQQHLQQQINQQQLQ-------QQLQQRLQLQQLQHM-QHQSQPSPRQHS 529



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 13/111 (11%)

Query: 468 EINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQ 527
           +++++IQ++++  +F       + +    Q+ Q ++Q+ +Q+  +++ +QR  L+ +L  
Sbjct: 463 QMHQQIQQQMQQQHF-----QHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQ-QLQH 516

Query: 528 THFQSQGQGQSQNPNQNQSQ-------NPNPNANQNLTQNLMQNLTQSLSQ 571
              QSQ   +  +P  +Q         +P P + Q+ +Q   Q  TQ LSQ
Sbjct: 517 MQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLSQ 567


>gi|226054295 TOX high mobility group box family member 3 isoform 1
           [Homo sapiens]
          Length = 576

 Score = 37.4 bits (85), Expect = 0.040
 Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 464 ASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKG 523
           A S +++  +Q +   +     +     +   +Q+ Q  + + HQ+ +++ Q+Q      
Sbjct: 427 APSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHF---Q 483

Query: 524 RLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRESPKQNS 582
             +Q H Q Q Q   Q  NQ Q Q       Q L Q L     Q + Q +++ SP+Q+S
Sbjct: 484 HHMQQHLQQQQQHLQQQINQQQLQ-------QQLQQRLQLQQLQHM-QHQSQPSPRQHS 534



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 13/111 (11%)

Query: 468 EINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQ 527
           +++++IQ++++  +F       + +    Q+ Q ++Q+ +Q+  +++ +QR  L+ +L  
Sbjct: 468 QMHQQIQQQMQQQHF-----QHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQ-QLQH 521

Query: 528 THFQSQGQGQSQNPNQNQSQ-------NPNPNANQNLTQNLMQNLTQSLSQ 571
              QSQ   +  +P  +Q         +P P + Q+ +Q   Q  TQ LSQ
Sbjct: 522 MQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLSQ 572


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 37.4 bits (85), Expect = 0.040
 Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 10/101 (9%)

Query: 497 QRYQFMRQKEHQEARRKRQEQRKFLKGRLL-QTHFQSQGQGQSQNPNQNQSQNPNPNANQ 555
           + Y   R++E++   R R  +R+   GR   +   + +   +S    ++QS+N +   NQ
Sbjct: 588 KEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQ 647

Query: 556 NLTQNLMQNLTQSLSQKENRESPKQNSGKEQNDNTSNGTND 596
                     ++S  +KEN ES K+   K ++ N+SN + +
Sbjct: 648 E---------SKSSHRKENSESEKRMYSKSRDHNSSNNSRE 679


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 36.6 bits (83), Expect = 0.069
 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 11/100 (11%)

Query: 497 QRYQFMRQKEHQEARRKRQEQRKFLKGRLLQT--HFQSQGQGQSQNPNQNQSQNPNPNAN 554
           Q+    R + H   R   + + +  KG L Q   H QS+    S+  +QNQS+ P    +
Sbjct: 295 QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRS--HSKGKSQNQSRTPRRGRS 352

Query: 555 QNLTQNLMQNLTQSLSQKENRE-------SPKQNSGKEQN 587
            N ++N  +  + S S+  ++E       SP++ SG+ Q+
Sbjct: 353 HNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQS 392


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 2/86 (2%)

Query: 513 KRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQN-PNPNANQN-LTQNLMQNLTQSLS 570
           K+ E  K L  R  +   +SQ Q Q Q   Q Q Q  P P ++Q    +   +   +   
Sbjct: 474 KKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEE 533

Query: 571 QKENRESPKQNSGKEQNDNTSNGTND 596
           +K   E+ K++  KE+ D+TS   ND
Sbjct: 534 EKPEVENDKEDLLKEKTDDTSGEDND 559


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 2/86 (2%)

Query: 513 KRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQN-PNPNANQN-LTQNLMQNLTQSLS 570
           K+ E  K L  R  +   +SQ Q Q Q   Q Q Q  P P ++Q    +   +   +   
Sbjct: 474 KKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEE 533

Query: 571 QKENRESPKQNSGKEQNDNTSNGTND 596
           +K   E+ K++  KE+ D+TS   ND
Sbjct: 534 EKPEVENDKEDLLKEKTDDTSGEDND 559


>gi|30911103 pygopus homolog 1 [Homo sapiens]
          Length = 419

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 20/64 (31%), Positives = 38/64 (59%), Gaps = 3/64 (4%)

Query: 535 QGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKE--NRESPKQNSGKEQNDNTSN 592
           QG ++N NQN S +P P+ N + T N      +++++    N+E+ + +S +  N+N +N
Sbjct: 243 QGATKNTNQNSSAHP-PHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPAN 301

Query: 593 GTND 596
           GT +
Sbjct: 302 GTQN 305


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 10/91 (10%)

Query: 492 KDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNP------NQNQ 545
           + L LQ  Q  +Q++ Q+ ++++Q+Q++  + +  Q   Q Q Q Q Q+P       Q Q
Sbjct: 144 EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 203

Query: 546 SQNPNPNANQNLT--QNLMQNLTQSLSQKEN 574
            Q     A Q L   Q L+Q   Q L Q+++
Sbjct: 204 QQQQQQLAAQQLVFQQQLLQ--MQQLQQQQH 232



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 490 YAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNP 549
           Y K       Q ++Q++ Q+ ++++Q+Q+     +  Q   Q Q Q Q Q   Q Q Q+P
Sbjct: 139 YKKQQEQLHLQLLQQQQQQQQQQQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQHP 193

Query: 550 NPNANQNLTQNLMQ 563
              A +   Q   Q
Sbjct: 194 GKQAKEQQQQQQQQ 207


>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
          Length = 623

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 10/91 (10%)

Query: 492 KDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNP------NQNQ 545
           + L LQ  Q  +Q++ Q+ ++++Q+Q++  + +  Q   Q Q Q Q Q+P       Q Q
Sbjct: 52  EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 111

Query: 546 SQNPNPNANQNLT--QNLMQNLTQSLSQKEN 574
            Q     A Q L   Q L+Q   Q L Q+++
Sbjct: 112 QQQQQQLAAQQLVFQQQLLQ--MQQLQQQQH 140



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 490 YAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNP 549
           Y K       Q ++Q++ Q+ ++++Q+Q+     +  Q   Q Q Q Q Q   Q Q Q+P
Sbjct: 47  YKKQQEQLHLQLLQQQQQQQQQQQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQHP 101

Query: 550 NPNANQNLTQNLMQ 563
              A +   Q   Q
Sbjct: 102 GKQAKEQQQQQQQQ 115


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 10/91 (10%)

Query: 492 KDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNP------NQNQ 545
           + L LQ  Q  +Q++ Q+ ++++Q+Q++  + +  Q   Q Q Q Q Q+P       Q Q
Sbjct: 169 EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 228

Query: 546 SQNPNPNANQNLT--QNLMQNLTQSLSQKEN 574
            Q     A Q L   Q L+Q   Q L Q+++
Sbjct: 229 QQQQQQLAAQQLVFQQQLLQ--MQQLQQQQH 257



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 490 YAKDLFLQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNP 549
           Y K       Q ++Q++ Q+ ++++Q+Q+     +  Q   Q Q Q Q Q   Q Q Q+P
Sbjct: 164 YKKQQEQLHLQLLQQQQQQQQQQQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQHP 218

Query: 550 NPNANQNLTQNLMQ 563
              A +   Q   Q
Sbjct: 219 GKQAKEQQQQQQQQ 232


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 32/133 (24%), Positives = 63/133 (47%), Gaps = 19/133 (14%)

Query: 396 DLTLVGCYNLSVMPEKQRNKVL--LESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFI 453
           +L+ V  YN  +  E+Q+ + L  LES +  ++ M      E Q+  +   E+       
Sbjct: 585 NLSAVMLYNPGLEFERQQREELEKLESKRKLIEEME-----EKQKSDKAELERMQQ---- 635

Query: 454 SPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQF----MRQKEHQE 509
               +  T R  +  +  +I+K+ E L      + +  KDL  ++ +F    +R+++  E
Sbjct: 636 ----EVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIE 691

Query: 510 ARRKRQEQRKFLK 522
            ++KRQE+  FL+
Sbjct: 692 LQKKRQEEETFLR 704


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo
           sapiens]
          Length = 2161

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 34/111 (30%), Positives = 46/111 (41%), Gaps = 14/111 (12%)

Query: 1   MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSV--AASVRAGPPRGV 58
           MALP   V  F  P     GAP  T+  +  S+  A       G++  A+S R    R  
Sbjct: 443 MALPDWMV--FSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSP 500

Query: 59  SHGFHTRPLLDKPRKASSSLA----------GAACAPLFALLSRGRRRRMH 99
           S G H      +PR   SS            G +  P  +L SRGRRR+++
Sbjct: 501 SRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGRRRKLY 551


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 33.5 bits (75), Expect = 0.58
 Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 8/134 (5%)

Query: 468 EINEEIQKRIEGLNF-LDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQR----KFLK 522
           ++N+++++  + L+  LD EL    + L +++ Q +   E QE   K  EQ+    K  +
Sbjct: 118 QLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPE 177

Query: 523 GRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQ---NLTQNLMQNLTQSLSQKENRESPK 579
            +  Q     Q +GQ + P Q + Q   P   +    L +     L     Q+   E P+
Sbjct: 178 QQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQ 237

Query: 580 QNSGKEQNDNTSNG 593
           Q  G+ +      G
Sbjct: 238 QQEGQLELSEQQEG 251


>gi|14165274 golgi-associated microtubule-binding protein HOOK3
           [Homo sapiens]
          Length = 718

 Score = 33.5 bits (75), Expect = 0.58
 Identities = 38/158 (24%), Positives = 75/158 (47%), Gaps = 7/158 (4%)

Query: 434 TEFQRKTQYLFEKTFNMNFISPFTQYNTTRAS-SVEINEEIQKRIEGLNFLDMELYSYAK 492
           TE +   Q L E    +  +    Q   ++A  SV + +++++ +E L+  + EL     
Sbjct: 508 TENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQKKRA 567

Query: 493 DLFLQRYQF----MRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQN 548
            +     +F    ++ +E QEA RK++E+ K ++ R  +   +++   ++ +P QNQ   
Sbjct: 568 IIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAA 627

Query: 549 PNPNANQNLTQNLMQNLTQSLSQKENRESPKQNSGKEQ 586
           P   A +N  Q     L  SL +KE  ++  Q   +E+
Sbjct: 628 PEIQALKNQLQE-RDRLFHSL-EKEYEKTKSQREMEEK 663


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 33.5 bits (75), Expect = 0.58
 Identities = 24/135 (17%), Positives = 58/135 (42%), Gaps = 5/135 (3%)

Query: 460 NTTRASSVEINEEIQKRIEG----LNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQ 515
           N  R +  E+ E+++K+ +G      F +    ++ K+L   R + +   E    +R+R+
Sbjct: 25  NRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRK 84

Query: 516 EQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENR 575
           ++ K   GR   +   S     S + ++++ +       +   ++  ++   S+S+ E+ 
Sbjct: 85  KKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRS-HKSSESSMSETESD 143

Query: 576 ESPKQNSGKEQNDNT 590
                   K+  D T
Sbjct: 144 SKDSLKKKKKSKDGT 158


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 33.5 bits (75), Expect = 0.58
 Identities = 24/135 (17%), Positives = 58/135 (42%), Gaps = 5/135 (3%)

Query: 460 NTTRASSVEINEEIQKRIEG----LNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQ 515
           N  R +  E+ E+++K+ +G      F +    ++ K+L   R + +   E    +R+R+
Sbjct: 35  NRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRK 94

Query: 516 EQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENR 575
           ++ K   GR   +   S     S + ++++ +       +   ++  ++   S+S+ E+ 
Sbjct: 95  KKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRS-HKSSESSMSETESD 153

Query: 576 ESPKQNSGKEQNDNT 590
                   K+  D T
Sbjct: 154 SKDSLKKKKKSKDGT 168


>gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 1 isoform 1 [Homo sapiens]
          Length = 1861

 Score = 33.1 bits (74), Expect = 0.76
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 496  LQRYQFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNA-- 553
            LQR Q  +Q+    A     E  +      L  HF S+   + +   Q +S +P P +  
Sbjct: 1420 LQRSQQQKQQGPLPAPLNDSENEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQP 1479

Query: 554  NQNLTQNLMQNLTQSLSQKENRESPKQNSG 583
            + ++  + ++NL + L  K    SP+  +G
Sbjct: 1480 SSSVPSSYIRNLQEGLQSKGRPVSPQSRAG 1509


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 24/100 (24%), Positives = 45/100 (45%), Gaps = 29/100 (29%)

Query: 503 RQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLM 562
           + + H+ +  KR  +RK            S+  G+ +   +++S++P             
Sbjct: 358 KSRTHKHSPEKRGSERK---------EGSSRSHGREERSRRSRSRSPG------------ 396

Query: 563 QNLTQSLSQKENRESPKQNSGKEQ---NDNTSNGTNDYIG 599
                S  Q+E R+  ++N G+EQ   ND+ S+GT+ Y G
Sbjct: 397 -----SYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRG 431


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
          Length = 1293

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 500  QFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQ 559
            QF+ ++  Q+A ++RQ+Q         Q   Q Q Q   Q P Q Q Q+     N +   
Sbjct: 1184 QFLERRAKQKANQQRQQQ---------QLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLH 1234

Query: 560  NLMQNLTQSLSQKENRESPKQNSGKEQ 586
            ++ Q   QS +Q+ N E+ +    K++
Sbjct: 1235 SVFQT-NQSNNQQSNFEAVQSGKKKKK 1260


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
          Length = 1320

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 500  QFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQ 559
            QF+ ++  Q+A ++RQ+Q         Q   Q Q Q   Q P Q Q Q+     N +   
Sbjct: 1211 QFLERRAKQKANQQRQQQ---------QLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLH 1261

Query: 560  NLMQNLTQSLSQKENRESPKQNSGKEQ 586
            ++ Q   QS +Q+ N E+ +    K++
Sbjct: 1262 SVFQT-NQSNNQQSNFEAVQSGKKKKK 1287


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 500  QFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQ 559
            QF+ ++  Q+A ++RQ+Q         Q   Q Q Q   Q P Q Q Q+     N +   
Sbjct: 1190 QFLERRAKQKANQQRQQQ---------QLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLH 1240

Query: 560  NLMQNLTQSLSQKENRESPKQNSGKEQ 586
            ++ Q   QS +Q+ N E+ +    K++
Sbjct: 1241 SVFQT-NQSNNQQSNFEAVQSGKKKKK 1266


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 500  QFMRQKEHQEARRKRQEQRKFLKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQ 559
            QF+ ++  Q+A ++RQ+Q         Q   Q Q Q   Q P Q Q Q+     N +   
Sbjct: 1190 QFLERRAKQKANQQRQQQ---------QLPQQQQQQPPQQPPQQPQQQDSVWGMNHSTLH 1240

Query: 560  NLMQNLTQSLSQKENRESPKQNSGKEQ 586
            ++ Q   QS +Q+ N E+ +    K++
Sbjct: 1241 SVFQT-NQSNNQQSNFEAVQSGKKKKK 1266


>gi|45505178 cancer antigen 1 [Homo sapiens]
          Length = 641

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 46/204 (22%), Positives = 86/204 (42%), Gaps = 30/204 (14%)

Query: 385 LANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLE----SAKSNLKHMAFFGLTEFQRK- 439
           L  N   + L +L  V       + E + +K +L+      K+N   +    +TE Q+K 
Sbjct: 237 LEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKN 296

Query: 440 ---TQYL-FEKTFNMNFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLF 495
              +QYL  +KT +             +   VE  ++++K +E      ++L    K+  
Sbjct: 297 KSVSQYLEMDKTLSK------------KEEEVERLQQLKKELEKATASALDLLKREKEAQ 344

Query: 496 LQRYQFMRQKEHQEARRKRQEQRKFLKGRL-------LQTHFQSQGQGQSQNPNQNQSQN 548
            Q +  + Q+E Q+  ++  E+R+ LK RL           F S+ + +++N    Q  N
Sbjct: 345 EQEFLSL-QEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENE-RTKNIKLQQQIN 402

Query: 549 PNPNANQNLTQNLMQNLTQSLSQK 572
              N N  L Q + ++  Q+   K
Sbjct: 403 EVKNENAKLKQQVARSEEQNYVPK 426


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,752,613
Number of Sequences: 37866
Number of extensions: 1177467
Number of successful extensions: 4801
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 4553
Number of HSP's gapped (non-prelim): 313
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.