Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 116256453
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
(2524 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 5115 0.0
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 4948 0.0
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 1498 0.0
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 112 4e-24
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 112 4e-24
gi|209977080 REST corepressor 3 isoform a [Homo sapiens] 112 5e-24
gi|8922733 REST corepressor 3 isoform d [Homo sapiens] 112 5e-24
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 106 3e-22
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 106 3e-22
gi|7661892 REST corepressor 1 [Homo sapiens] 105 6e-22
gi|163965366 nascent polypeptide-associated complex alpha subuni... 101 1e-20
gi|209977084 REST corepressor 3 isoform c [Homo sapiens] 100 1e-20
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 100 3e-20
gi|27734799 REST corepressor 2 [Homo sapiens] 100 3e-20
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 92 8e-18
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 92 8e-18
gi|210032580 SET domain containing 1B [Homo sapiens] 90 2e-17
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 88 9e-17
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 88 1e-16
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 86 4e-16
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 86 6e-16
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 84 1e-15
gi|150170670 piccolo isoform 2 [Homo sapiens] 83 4e-15
gi|150378539 piccolo isoform 1 [Homo sapiens] 83 4e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 82 7e-15
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 82 7e-15
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 80 2e-14
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 80 3e-14
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 78 1e-13
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 78 1e-13
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 5115 bits (13269), Expect = 0.0
Identities = 2524/2524 (100%), Positives = 2524/2524 (100%)
Query: 1 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ 60
MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ
Sbjct: 1 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ 60
Query: 61 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP 120
PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP
Sbjct: 61 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP 120
Query: 121 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD 180
SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD
Sbjct: 121 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD 180
Query: 181 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA 240
REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA
Sbjct: 181 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA 240
Query: 241 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ 300
AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ
Sbjct: 241 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ 300
Query: 301 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG 360
RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG
Sbjct: 301 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG 360
Query: 361 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM 420
LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM
Sbjct: 361 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM 420
Query: 421 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK 480
KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK
Sbjct: 421 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK 480
Query: 481 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN 540
SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN
Sbjct: 481 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN 540
Query: 541 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ 600
DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ
Sbjct: 541 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ 600
Query: 601 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ 660
SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ
Sbjct: 601 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ 660
Query: 661 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE 720
NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE
Sbjct: 661 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE 720
Query: 721 AEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP 780
AEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP
Sbjct: 721 AEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP 780
Query: 781 GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG 840
GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG
Sbjct: 781 GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG 840
Query: 841 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS 900
EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS
Sbjct: 841 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS 900
Query: 901 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP 960
GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP
Sbjct: 901 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP 960
Query: 961 LDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRG 1020
LDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRG
Sbjct: 961 LDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRG 1020
Query: 1021 KSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPS 1080
KSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPS
Sbjct: 1021 KSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPS 1080
Query: 1081 AFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQL 1140
AFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQL
Sbjct: 1081 AFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQL 1140
Query: 1141 HVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEAS 1200
HVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEAS
Sbjct: 1141 HVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEAS 1200
Query: 1201 VLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPS 1260
VLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPS
Sbjct: 1201 VLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPS 1260
Query: 1261 RLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDM 1320
RLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDM
Sbjct: 1261 RLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDM 1320
Query: 1321 MEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRR 1380
MEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRR
Sbjct: 1321 MEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRR 1380
Query: 1381 EAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREEL 1440
EAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREEL
Sbjct: 1381 EAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREEL 1440
Query: 1441 RHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVM 1500
RHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVM
Sbjct: 1441 RHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVM 1500
Query: 1501 ADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGH 1560
ADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGH
Sbjct: 1501 ADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGH 1560
Query: 1561 LPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEH 1620
LPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEH
Sbjct: 1561 LPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEH 1620
Query: 1621 LLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGY 1680
LLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGY
Sbjct: 1621 LLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGY 1680
Query: 1681 PDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGIID 1740
PDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGIID
Sbjct: 1681 PDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGIID 1740
Query: 1741 LSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSS 1800
LSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSS
Sbjct: 1741 LSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSS 1800
Query: 1801 SERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPAS 1860
SERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPAS
Sbjct: 1801 SERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPAS 1860
Query: 1861 HSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATF 1920
HSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATF
Sbjct: 1861 HSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATF 1920
Query: 1921 PPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPAS 1980
PPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPAS
Sbjct: 1921 PPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPAS 1980
Query: 1981 SPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSI 2040
SPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSI
Sbjct: 1981 SPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSI 2040
Query: 2041 QELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGP 2100
QELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGP
Sbjct: 2041 QELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGP 2100
Query: 2101 VKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQ 2160
VKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQ
Sbjct: 2101 VKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQ 2160
Query: 2161 QLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTS 2220
QLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTS
Sbjct: 2161 QLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTS 2220
Query: 2221 VLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFS 2280
VLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFS
Sbjct: 2221 VLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFS 2280
Query: 2281 KLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQ 2340
KLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQ
Sbjct: 2281 KLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQ 2340
Query: 2341 EHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHT 2400
EHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHT
Sbjct: 2341 EHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHT 2400
Query: 2401 LTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDR 2460
LTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDR
Sbjct: 2401 LTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDR 2460
Query: 2461 PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETL 2520
PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETL
Sbjct: 2461 PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETL 2520
Query: 2521 SDSE 2524
SDSE
Sbjct: 2521 SDSE 2524
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 4948 bits (12835), Expect = 0.0
Identities = 2461/2525 (97%), Positives = 2461/2525 (97%), Gaps = 64/2525 (2%)
Query: 1 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ 60
MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ
Sbjct: 1 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ 60
Query: 61 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP 120
PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP
Sbjct: 61 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP 120
Query: 121 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD 180
SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD
Sbjct: 121 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD 180
Query: 181 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA 240
REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA
Sbjct: 181 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA 240
Query: 241 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ 300
AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ
Sbjct: 241 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ 300
Query: 301 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG 360
RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG
Sbjct: 301 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG 360
Query: 361 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM 420
LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM
Sbjct: 361 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM 420
Query: 421 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK 480
KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK
Sbjct: 421 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK 480
Query: 481 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN 540
SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN
Sbjct: 481 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN 540
Query: 541 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ 600
DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ
Sbjct: 541 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ 600
Query: 601 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ 660
SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ
Sbjct: 601 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ 660
Query: 661 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE 720
NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE
Sbjct: 661 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE 720
Query: 721 AEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP 780
AEA TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP
Sbjct: 721 AEA-----------------TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP 763
Query: 781 GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG 840
GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG
Sbjct: 764 GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG 823
Query: 841 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS 900
EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS
Sbjct: 824 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS 883
Query: 901 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP 960
GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP
Sbjct: 884 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP 943
Query: 961 LDLKQLKQRAAAIPPI-VTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR 1019
LDLKQLKQRAAAIPPI VTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR
Sbjct: 944 LDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR 1003
Query: 1020 GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP 1079
GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP
Sbjct: 1004 GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP 1063
Query: 1080 SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ 1139
SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ
Sbjct: 1064 SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ 1123
Query: 1140 LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA 1199
LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA
Sbjct: 1124 LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA 1183
Query: 1200 SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP 1259
SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP
Sbjct: 1184 SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP 1243
Query: 1260 SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD 1319
SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD
Sbjct: 1244 SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD 1303
Query: 1320 MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR 1379
MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR
Sbjct: 1304 MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR 1363
Query: 1380 REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE 1439
REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE
Sbjct: 1364 REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE 1423
Query: 1440 LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV 1499
LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV
Sbjct: 1424 LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV 1483
Query: 1500 MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG 1559
MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG
Sbjct: 1484 MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG 1543
Query: 1560 HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE 1619
HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE
Sbjct: 1544 HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE 1603
Query: 1620 HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG 1679
HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG
Sbjct: 1604 HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG 1663
Query: 1680 YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII 1739
YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII
Sbjct: 1664 YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII 1723
Query: 1740 DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS 1799
DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS
Sbjct: 1724 DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS 1783
Query: 1800 SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPA 1859
SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPA
Sbjct: 1784 SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPA 1843
Query: 1860 SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT 1919
SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT
Sbjct: 1844 SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT 1903
Query: 1920 FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA 1979
FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA
Sbjct: 1904 FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA 1963
Query: 1980 SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS 2039
SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS
Sbjct: 1964 SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS 2023
Query: 2040 IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG 2099
IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG
Sbjct: 2024 IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG 2083
Query: 2100 PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP 2159
PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP
Sbjct: 2084 PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP 2143
Query: 2160 QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT 2219
QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT
Sbjct: 2144 QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT 2203
Query: 2220 SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF 2279
SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF
Sbjct: 2204 SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF 2263
Query: 2280 SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAV 2339
SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAV
Sbjct: 2264 SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAV 2323
Query: 2340 QEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDH 2399
QEHASTNMGLEAIIRKALM
Sbjct: 2324 QEHASTNMGLEAIIRKALM----------------------------------------- 2342
Query: 2400 TLTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWED 2459
GGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWED
Sbjct: 2343 -----GGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWED 2397
Query: 2460 RPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYET 2519
RPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYET
Sbjct: 2398 RPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYET 2457
Query: 2520 LSDSE 2524
LSDSE
Sbjct: 2458 LSDSE 2462
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 1498 bits (3877), Expect = 0.0
Identities = 1086/2660 (40%), Positives = 1442/2660 (54%), Gaps = 357/2660 (13%)
Query: 1 MSGSTQPVAQTWRATEP-RYPPHSLSYPVQIARTHTDVGLLEYQ--HHSRDYASHLSPGS 57
MS S P Q +TE RYPPHS+ Y R + + +Y+ H AS L
Sbjct: 1 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ 60
Query: 58 IIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPD-- 115
Q RRRPSLLSEF PG++R QE R + P + + +ESKRPRLE + D
Sbjct: 61 QQQQLRRRPSLLSEFHPGSDRPQER--RTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSH 118
Query: 116 ---------PLLRPSPLLATGQPAGSEDLTKDRSLTGKLE-PVSPPSPPHTDPELELVPP 165
PL+ P P G A S D KD + GK E P SP S + P
Sbjct: 119 FQRVSAAVLPLVHPLP---EGLRA-SADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPS 174
Query: 166 RLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRS 225
+LSKEELIQ+MDRVDREI VEQQI KLKKKQQQLEEEAAKPPEPEKPVSPPP+E KHRS
Sbjct: 175 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRS 234
Query: 226 LVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFK 285
+VQIIYDENRKKAE AH+I EGLGP+VELPLYNQPSDT+ YHENIK NQ MRKKLIL+FK
Sbjct: 235 IVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFK 294
Query: 286 RRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRE 345
RRNHARKQ EQK CQRYDQLMEAWEKKV+RIENNPRR+AKESK REYYEKQFPEIRKQRE
Sbjct: 295 RRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQRE 354
Query: 346 LQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQ 405
QER Q RVGQRG+GLS + ARSEHE+SEIIDGLSEQEN EKQMRQL+VIPPM++DA+Q+
Sbjct: 355 QQERFQ-RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 413
Query: 406 RIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAE 465
R+KFINMNGLM DPMKVYKDRQ MN+W++ EKE F++KF+QHPKNFGLIAS+LERK+V +
Sbjct: 414 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 473
Query: 466 CVLYYYLTKKNENYKSLVRRSY-RRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKE 524
CVLYYYLTKKNENYK+LVRR+Y +RRG++QQ + Q+++ +++++ ++ + EK E+E
Sbjct: 474 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEE--DKAEKTEKKEEE 531
Query: 525 KEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITR 584
K+ E EK+E++ EN KE K+K D T+ E+ +E+E +GRKTANSQGRRKGRITR
Sbjct: 532 KKDEEEKDEKEDSKENTKE---KDKIDGTA-EETEEREQATPRGRKTANSQGRRKGRITR 587
Query: 585 SMANEANSEEAITPQQS----------AELASMELNESSRWTEEEMETAKKGLLEHGRNW 634
SM NEA + A + E S E E+SRWTEEEME AKKGL+EHGRNW
Sbjct: 588 SMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNW 647
Query: 635 SAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEA 694
+AIA+MVG+K+ +QCKNFYFNYK+R NLD +LQQHK K ++ R + + AS +
Sbjct: 648 AAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVS 707
Query: 695 AFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSP 754
A EDE++EAS NEEE E++E E + P + +TE P+
Sbjct: 708 A----QEDEDIEAS----NEEENPEDSEV------EAVKPSEDSPENATSRGNTE--PAV 751
Query: 755 HTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPS 814
E +T P +L P T P ED T+ +++ A T
Sbjct: 752 ELEPTTET---APSTSPSLAV------PSTKPAEDESVETQ---VNDSISAET------- 792
Query: 815 PSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGP 874
+ V +E EE + P PPA + +VD E V + E
Sbjct: 793 -AEQMDVDQQEHSAEEGSVCDP--------PPATKADSVD---VEVRVPENHASKVEGDN 840
Query: 875 AKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDK 934
K +D + A E ++ + A+ D+DSSATCSADE + +G +
Sbjct: 841 TKERDLDRASEKVE----PRDEDLVVAQQINAQRPEPQSDNDSSATCSADE--DVDGEPE 894
Query: 935 NRLLSP---RPSLLTPTGDPRANASPQK--PLDLKQLKQRAAAIPPIVTKVHEPPREDAA 989
+ + P +PSLL PTG +SP K PLDL QL+ RAA IPP+V+
Sbjct: 895 RQRMFPMDSKPSLLNPTGSILV-SSPLKPNPLDLPQLQHRAAVIPPMVS---------CT 944
Query: 990 PTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL 1049
P P P + S+ + R D E
Sbjct: 945 PCN-IPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRS-------------- 989
Query: 1050 PGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTI 1109
PC TS P EV++ +PH + P G LP T RP P PP I
Sbjct: 990 -STSPCGTS--KSPNREWEVLQPAPH----QVITNLPEGVRLP-----TTRPTRPPPPLI 1037
Query: 1110 SNPPPLISSAKHPSVLERQIGAISQG-----MSVQLHVPYSEHAKAP-VGPVTMGLPLPM 1163
+ ++S K ++ G+ISQG ++ Y++ P VG +++GLP
Sbjct: 1038 PSSKTTVASEKPSFIMG---GSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQ 1094
Query: 1164 DPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTR 1223
+ K A +KQE+ SPR Q PE L V AQ V+RGTA G++ GSIT+G P+++
Sbjct: 1095 ESAKSATLPYIKQEEFSPRSQNSQPEGLLV-RAQHEGVVRGTA-GAIQEGSITRGTPTSK 1152
Query: 1224 VPSDSAITYRGSITHGTPA--------DVLYKGTITRIIGEDSPSRLDRGREDSLPKGHV 1275
+ +S + RGSIT GTPA + L KG+I+R+ EDS ++GRE++ KGHV
Sbjct: 1153 ISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSP--EKGREEAASKGHV 1210
Query: 1276 IYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAIS----- 1330
IYEGK GH+LSY+ + +G S HE + KR+Y+ +EG + + +S
Sbjct: 1211 IYEGKSGHILSYDNIKNA-----REGTRSPRTAHEISL-KRSYESVEGNIKQGMSMRESP 1264
Query: 1331 -SASIEGLMGRAIPPERHSPH-HLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKRE 1388
SA +EGL+ RA+P R SPH LKE+ + GSI QG PR+ E+ ED L + K +KRE
Sbjct: 1265 VSAPLEGLICRALP--RGSPHSDLKERTVLSGSIMQGTPRATTESFEDGL-KYPKQIKRE 1321
Query: 1389 GTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREEL-----RHT 1443
PP R A K KP ++G + T+KE GRSIHEIPR+++ R T
Sbjct: 1322 S-----PPIRAFEGAI-------TKGKP-YDG-ITTIKEMGRSIHEIPRQDILTQESRKT 1367
Query: 1444 PELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMAD- 1502
PE+ + RP+ EGSI+QGTP+K+D S + KH+V+SLI P + + PL+++ +
Sbjct: 1368 PEVVQSTRPIIEGSISQGTPIKFDNN-SGQSAIKHNVKSLITGPSKLSRGMPPLEIVPEN 1426
Query: 1503 ARALERACYE-----ESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGA-- 1555
+ +ER YE E+++SR + SSG S+ R + E K + SP Y+D A
Sbjct: 1427 IKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRST---LHEAPKAQLSPGIYDDTSARR 1483
Query: 1556 ---PFAGHLPRGSPVTTREPTPRLQEGSLSSSKA-SQDRKLTSTPRE----IAKSPHSTV 1607
+ + RGSP+ R + ++SS+K+ + +RK T TP + AKSP V
Sbjct: 1484 TPVSYQNTMSRGSPMMN-----RTSDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGV 1538
Query: 1608 PEHHPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLD-AAAAYYLPRHLAPNP 1666
H SP++ RG + ++YRSH+P DP ++P LD AAAAY R L+P P
Sbjct: 1539 DPVVSH--SPFDPHHRGSTAGEVYRSHLPTHLDP-AMPFHRALDPAAAAYLFQRQLSPTP 1595
Query: 1667 TYPHLYPPYLIRGYPDTAALEN-RQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRES 1725
YP Y Y A+EN RQTI+NDYITSQQM N R D+ RGLSPRE
Sbjct: 1596 GYPSQYQLY---------AMENTRQTILNDYITSQQMQVNL------RPDVARGLSPREQ 1640
Query: 1726 SLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSR-HSSSPL 1784
L L Y A RGIIDL+ +P +LVP GT MDR+ Y+P F R ++S+ +
Sbjct: 1641 PLGLPYPA-TRGIIDLTNMPP-TILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASM 1698
Query: 1785 SPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGS 1844
SPG PTHL +S+ERER+R+RE++R+RER I +++ + RPG+EQ
Sbjct: 1699 SPGHPTHL---AAAASAEREREREREKERERER---IAAASSDL----YLRPGSEQ---- 1744
Query: 1845 SGSSGGGGGSSSRPASHSHAHQHSPISPRTQDA-LQQRPSVLHNTGMKGIITAVEPSTPT 1903
RP SH + SP S RTQ+ LQQRPSV T +IT ++P+
Sbjct: 1745 ----------PGRPGSHGYVRSPSP-SVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQL 1793
Query: 1904 VLRSTSTSSPV----RPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPR-------- 1951
+ P PA+ + A L +D V KE+
Sbjct: 1794 RIMPLPAGGPSISQGLPASRYNTAADA-LAALVDAAASAPQMDVSKTKESKHEAARLEEN 1852
Query: 1952 -----VARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLV-----------PPV 1995
A E+ + + + K + ++ PS +P V PP
Sbjct: 1853 LRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPK 1912
Query: 1996 SGHATIARTPAKN--LAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGS 2053
S + RT K A + AS D +QS S SL H
Sbjct: 1913 SRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSS------SSLSSHRY 1966
Query: 2054 SYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHL 2113
+ +E +SP SSP+ +K E + + E + + GP L H
Sbjct: 1967 ETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGP---------LHHY 2017
Query: 2114 RPLPESQPSSSPLLQTAPG--------VKGHQRVVTLAQHISEVITQDYTRHHPQQLSAP 2165
RP Q S SP Q P V R++TLA HI ++ITQD+ R+ P
Sbjct: 2018 RP---QQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSS-QTP 2073
Query: 2166 LPAPLYSFPGASCPVLD--LRRPPSDLYLPPPD-----HGAP-ARGSPH-----SEGGKR 2212
P +F + ++ +R S+ Y P H P +R SP S G +
Sbjct: 2074 QQPPTSTFQNSPSALVSTPVRTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRGSRP 2133
Query: 2213 SPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNT 2272
P ++ V + EP+SPP+ H + LL + G + R ++SPG+
Sbjct: 2134 GKSPERSHV---SSEPYEPISPPQ--VPVVHEKQDSLLLLSQRGAEPAEQRNDARSPGSI 2188
Query: 2273 SQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLM 2332
S P+FF+KL E+ S MVKSKKQEI +KLN+ + + +QPGTEIFN+PA+T +G +
Sbjct: 2189 SYLPSFFTKL-ENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTSGSV 2247
Query: 2333 TYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITA 2392
+ R + + AS N+GLE IIRKALMG +D E + + P+ +T+
Sbjct: 2248 SSRGHSFADPAS-NLGLEDIIRKALMGSFDDKVEDHGVVMS--QPMGVVPGTANTSVVTS 2304
Query: 2393 ADGRSDHTLTSPGGGG--KAKVSGRPSSRKAKSPAP--GLASGDRPPSVSSVHSEGDCNR 2448
+ R + SP GG K K+ + +SRK+KSP P G +RP SVSSVHSEGD +R
Sbjct: 2305 GETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHR 2364
Query: 2449 RTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSG-PLAGPH---HA 2504
+TP WEDRPSS GST FPYNPL MR+ + ++PP P A S A PH
Sbjct: 2365 QTP--GWAWEDRPSSTGSTQFPYNPLTMRM---LSSTPPTPIACAPSAVNQAAPHQQNRI 2419
Query: 2505 WDEEPKPLLCSQYETLSDSE 2524
W+ EP PLL +QYETLSDS+
Sbjct: 2420 WEREPAPLLSAQYETLSDSD 2439
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 112 bits (281), Expect = 4e-24
Identities = 168/732 (22%), Positives = 249/732 (34%), Gaps = 99/732 (13%)
Query: 495 QQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKE-EEKPEVENDKEDLLKEKT--- 550
++ + Q+ SS K + K A +E ++K +V+++K++ K+K
Sbjct: 115 EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPK 174
Query: 551 -----DDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ-SAEL 604
+ SG DN + + T +++ +IT A N ++ P +++
Sbjct: 175 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNSDTSKE 232
Query: 605 ASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDE 664
S+ +N+ + +E T K G+ + A+ S + K+ K
Sbjct: 233 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK------- 285
Query: 665 ILQQHKLKME---KERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEA 721
+L + K E K K+ P E A+ P +E + + E A
Sbjct: 286 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP----KEPTPTTIKSAPTTPKEPA 341
Query: 722 EALHASGNEVPRGECSGPATVNNSSDTESIPSPHT--EAAKDTGQNGP------------ 767
S P+ E + T + T P+P T E A T ++ P
Sbjct: 342 PTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 400
Query: 768 KPPATLGADGPPPGP----PTPPPEDIPAPTEPTPASEATGAPTPP--PAPPSPSAPPPV 821
KP T + P P PT P E P EP P + APT P PAP +P P P
Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460
Query: 822 VPKE------EKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPA 875
PKE ++ T P + P +E A T K+ E + + PA
Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 520
Query: 876 KGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKN 935
E A T + KE A T AP + A + E
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKE----PAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPK 573
Query: 936 RLLSPRPSLLTPTGDPR-ANASPQKPLDLKQLKQRAAAIP--PIVTKVHEP--------- 983
P LTPT + A +P+KP ++ A P P T EP
Sbjct: 574 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-EELAPTTPEEPTPTTPEEPAPTTPKAAA 632
Query: 984 ---PREDA--APTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVF 1038
P+E A P +PAP P P P+ AP P + + PAP K+
Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK------ 686
Query: 1039 FPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDT 1098
PA A +P T P P P+ +P P P+ P P P T
Sbjct: 687 -PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-----PKEPAPTTPKGT 740
Query: 1099 ARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMG 1158
A P T+ P P P L + P + AP P
Sbjct: 741 A------PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-- 792
Query: 1159 LPLPMDPKKLAP 1170
P P PKK AP
Sbjct: 793 -PAPTTPKKPAP 803
Score = 95.9 bits (237), Expect = 4e-19
Identities = 170/727 (23%), Positives = 245/727 (33%), Gaps = 159/727 (21%)
Query: 617 EEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKE 676
E E T + + E+ + S+ + S T+ + K+ + R+ Q KLK++
Sbjct: 109 ESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRE------LQKKLKVKDN 162
Query: 677 RNARRKKKKAPAAASEEAAFPPVVED---------------------------------- 702
+ R KKK P PPVV++
Sbjct: 163 KKNRTKKKPTPK--------PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 214
Query: 703 -------------EEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTE 749
+ + + ++ N+E VE E + + G ++ +T+
Sbjct: 215 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN----KQTSTDGKEKTTSAKETQ 270
Query: 750 SI-----------------PSPHTEAA---------KDTGQNGPKPPATLGADGPPP--- 780
SI P+P E K+ PK PA+ P P
Sbjct: 271 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 330
Query: 781 -GPPTPPPEDIPAPTEPTPASEATGAP--TPPPAPPSPSAPPPVVPKEEKEEETAAAP-- 835
PT P E P T+ P + AP T PAP +P P P KE T +AP
Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 390
Query: 836 PVEEG------------EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAA 883
P E +E P +E T K P E + PA + A
Sbjct: 391 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
Query: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEV--DEAEGGDKNRLLSPR 941
T + KE + T S P++ + T SA + A K+ +P+
Sbjct: 451 PTTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 509
Query: 942 PSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEP----PREDAAPT--KPAP 995
T T +P A +P++P K P T EP P+E A T KPAP
Sbjct: 510 EPSPTTTKEP-APTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPAPTTTKKPAP 561
Query: 996 PAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPP---ADKEAEKPVFFPAFAAE-AQKLPG 1051
P P P+ AP P K +P P A EKP P E A P
Sbjct: 562 TTPKEPAPTTPKETAPTTP------KKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPE 613
Query: 1052 DPPCWTSGLPFPVPPREVIKASPHAPDPSA-FSYAP--PGHPLPLGLHDTARPVLPR--- 1105
+P T P P P+ +P P P+ AP P P P +TA P P+
Sbjct: 614 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA-PTTPKGTA 672
Query: 1106 PPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDP 1165
P T+ P P ++ K P+ E + S P K P T P P P
Sbjct: 673 PTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG-TAPTTPKEPAPTTP 729
Query: 1166 KKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPG-GSITKGIPSTRV 1224
K+ AP +P+G A PT + + A + G S T P+
Sbjct: 730 KEPAP--------TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781
Query: 1225 PSDSAIT 1231
P ++A T
Sbjct: 782 PKETAPT 788
Score = 93.6 bits (231), Expect = 2e-18
Identities = 103/394 (26%), Positives = 130/394 (32%), Gaps = 65/394 (16%)
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEP-- 796
P T ++ T P+P T + T P P T P P P PAPT P
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542
Query: 797 ---TPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853
T E T PAP +P P P PK ETA P ++ P E+LA
Sbjct: 543 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK-----ETAPTTP----KKLTPTTPEKLAP 593
Query: 854 DTGKAEEP-VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAP 912
T + P E E P E A T + A KE A T AP
Sbjct: 594 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPKEPAP 649
Query: 913 QDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAA 972
A + E +P+ + T +P A +P+KP K+L
Sbjct: 650 TTPKEPAPTTPKETAPT---------TPKGTAPTTLKEP-APTTPKKPAP-KELAPTTTK 698
Query: 973 IPPIVTKVHEPPREDAAPTKP---APPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPA 1029
P T + APT P AP P P P+ AP P + + PAP
Sbjct: 699 EPTSTT------CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 752
Query: 1030 DKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGH 1089
K+ PA A P TS P P P+E +P P P+
Sbjct: 753 PKK-------PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT-------- 797
Query: 1090 PLPLGLHDTARPVLPRPPTISNPPPLISSAKHPS 1123
P P P T PPP S P+
Sbjct: 798 -----------PKKPAPTTPETPPPTTSEVSTPT 820
Score = 71.2 bits (173), Expect = 1e-11
Identities = 123/544 (22%), Positives = 171/544 (31%), Gaps = 109/544 (20%)
Query: 783 PTPPPEDIPAPTEPTPASEATGAPTP-PPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGE 841
PT PP AP P+ AS+ + T P PP+ V+ EE EE + V E +
Sbjct: 69 PTSPPSSKKAP-PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHS----VSENQ 123
Query: 842 EQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKD-----------------AEAAE 884
E ++ + T + + K+ + K KD EA
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 183
Query: 885 ATAEGALKA---------EKKEGGSGRATTAK----SSGAPQDSDSS------------- 918
G K K S + TTAK P +SD+S
Sbjct: 184 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 243
Query: 919 ---ATCSADEVDEAEGGDKNR----------------------LLSPRPSLLTPTGDPRA 953
T + ++ +G +K L P P T T P A
Sbjct: 244 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-A 302
Query: 954 NASPQKPLDLKQLKQRAAAIP--PIVTKVHEPPREDAAP----TKPAPPAPPPPQNLQPE 1007
+P++P K+ A+ P P T + P P TK AP P P +
Sbjct: 303 LTTPKEPTPTTP-KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 1008 SDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPR 1067
AP P ++ PAP K A P A P P T P P P+
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-----APTTPKKPAPTTPKEPAPTTPK 416
Query: 1068 EVIKASPHAPDPSAFSYAP--PGHPLPLGLHDTA--RPVLPRPPTISNPPPLISSAKHPS 1123
E +P P P+ AP P P P A P P P T P P + P+
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 476
Query: 1124 VLERQIGAISQGMSVQLHVPYSEHAK-APV-----GPVTMGLPLPMDPKKLAPFSGVKQE 1177
+ ++ P K AP P T P P PK+ AP + K
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 536
Query: 1178 QLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSIT 1237
+P+ A PT + T P+ P ++A T +T
Sbjct: 537 PTTPKEPAPTTPKEPAPTTTKKP------------APTTPKEPAPTTPKETAPTTPKKLT 584
Query: 1238 HGTP 1241
TP
Sbjct: 585 PTTP 588
Score = 63.5 bits (153), Expect = 2e-09
Identities = 110/504 (21%), Positives = 159/504 (31%), Gaps = 82/504 (16%)
Query: 1745 PHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERE 1804
P P P P T + P P P + + + PT KP T+ E
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458
Query: 1805 RDRDRERDRDREREKSILT----STTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPAS 1860
+E +E S T + TT + AP T++ + ++ S P +
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT---TKEPAPTTTKSAPTTPKEPSPTT 515
Query: 1861 HSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATF 1920
+P P + P+ T + T + PT + + ++P PA T
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPT----TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 571
Query: 1921 PPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV--------------ARPERPRADTGHAF 1966
P T L P + P K AP PE P T A
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631
Query: 1967 L----AKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIART-PAKNLAPHHASPDPPAP 2021
+P + EPA P+ EP P P + T T P P +P PAP
Sbjct: 632 APNTPKEPAPTTPKEPA--PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Query: 2022 PASASDPHREKTQS---KPFSIQELELRSLGYHGSSYSPEGVEPVSP-------VSSPSL 2071
A +E T + KP + +P+G P +P P+
Sbjct: 690 KELAPTTTKEPTSTTCDKP---------------APTTPKGTAPTTPKEPAPTTPKEPAP 734
Query: 2072 THDKG-LPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHL----RPLPESQPSSSPL 2126
T KG P L+E PK+P P +L P +P P + ++P
Sbjct: 735 TTPKGTAPTTLKE------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788
Query: 2127 -----LQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVL 2181
T P T SEV T T+ P ++ P S P L
Sbjct: 789 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---------PTTIHKSPDESTPEL 839
Query: 2182 DLRRPPSDLYLPPPDHGAPARGSP 2205
P L P + G P +P
Sbjct: 840 SAEPTPKALENSPKEPGVPTTKTP 863
Score = 61.2 bits (147), Expect = 1e-08
Identities = 84/359 (23%), Positives = 128/359 (35%), Gaps = 52/359 (14%)
Query: 732 PRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIP 791
P+G + P T+ + T +P A K+ K P + +D P PT P E P
Sbjct: 737 PKG--TAPTTLKEPAPT----TPKKPAPKELAPTTTKGPTSTTSDKP---APTTPKETAP 787
Query: 792 -APTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEE----GEEQKPP 846
P EP P + APT P PP P+ P KE T P E E P
Sbjct: 788 TTPKEPAPTTPKKPAPTTPETPP-PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 846
Query: 847 AAE----ELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGR 902
A E E V T K K E T A++ + +D T A K K+
Sbjct: 847 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE-RDLRTTPETTTAAPKMTKE-----T 900
Query: 903 ATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLD 962
ATT + + ++S T + +V D +L T T P+ +
Sbjct: 901 ATTTEKT-----TESKITATTTQVTSTTTQDTTPF--KITTLKTTTLAPKVTTT------ 947
Query: 963 LKQLKQRAAAIPPIVTKVHE--PPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRG 1020
++ I+ K E P++ A +K P P P + + ++P + PR
Sbjct: 948 -----KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRV 1002
Query: 1021 KSRSPAP-PADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPD 1078
+ P P + P P L T+ P P ++++ +P + D
Sbjct: 1003 RKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ------TTTRPNQTPNSKLVEVNPKSED 1055
Score = 57.0 bits (136), Expect = 2e-07
Identities = 89/395 (22%), Positives = 141/395 (35%), Gaps = 51/395 (12%)
Query: 1748 PVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDR 1807
P L P TP T + + P P P + + S+P +P P PTTT S+
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIK--SAPTTPKEPA----PTTTKSAP---TT 351
Query: 1808 DRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQH 1867
+E +E + TT E AP T++ + ++ S P +
Sbjct: 352 PKEPAPTTTKEPA---PTTPKEPAP---TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 1868 SPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFP--PATH 1925
+P P + P+ T + T EP+ PT + + ++P +PA T P PA
Sbjct: 406 TPKEPAPTTPKEPTPT----TPKEPAPTTKEPA-PTTPKEPAPTAPKKPAPTTPKEPAPT 460
Query: 1926 CPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKG 1985
P EP + P P+ P T K + EPA + +K
Sbjct: 461 TP------------KEPAPTTTKEPSPTTPKEPAPTT-----TKSAPTTTKEPAPTTTKS 503
Query: 1986 SEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAP-------PASASDPHREKTQSKPF 2038
+ P P + A T K AP +P PAP P + +P T+
Sbjct: 504 APTTPKEPSPTTTKEPAPTTPKEPAP--TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 561
Query: 2039 SIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLE--GELRPK 2096
+ + + + +P+ + P +P T +K P EEL + E P+
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 621
Query: 2097 QPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAP 2131
+P P A + P P P + +P P
Sbjct: 622 EPAPTTPKAAAPNTPK-EPAPTTPKEPAPTTPKEP 655
Score = 56.2 bits (134), Expect = 4e-07
Identities = 155/780 (19%), Positives = 236/780 (30%), Gaps = 127/780 (16%)
Query: 1565 SPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRG 1624
+P TT+EP P + ++ T + K P T P+ P P +P E
Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEP---- 410
Query: 1625 VSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPN------PTYPHLYPPYLIR 1678
P PT+ P A P+ AP PT P P +
Sbjct: 411 -------APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Query: 1679 GYPDTAALENRQTIINDYI-TSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRG 1737
T E T + T+ + A +P+E S P
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-- 521
Query: 1738 IIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLT-KPT 1796
P P P P T + P P P +++ +P +P P T K T
Sbjct: 522 -----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK-KPAPTTPKEPAPTTPKET 575
Query: 1797 TTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIW----RPGTEQSSGSSGSSGGGG 1852
++ ++ E+ EK TT E AP P T + +
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 633
Query: 1853 GSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSS 1912
+ PA +P P + P+ T T + + PT L+ + ++
Sbjct: 634 NTPKEPA------PTTPKEPAPTTPKEPAPTTPKETAP----TTPKGTAPTTLKEPAPTT 683
Query: 1913 PVRPA--ATFPPATHCPLGGTLDGVYPTLME---PVLLPKEAPRVARPERPRADTGHA-- 1965
P +PA P T P T D PT + P + AP + P G A
Sbjct: 684 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743
Query: 1966 -------FLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDP 2018
K PA L P ++ S P + T TP + P +P
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE---PAPTTPKK 800
Query: 2019 PAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLP 2078
PAP + P S P + +E P + S+P L+ + P
Sbjct: 801 PAPTTPETPPPTTSEVSTPTTTKE--------------PTTIHKSPDESTPELSAEP-TP 845
Query: 2079 KHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPH-------------LRPLPE---SQPS 2122
K LE PK+PG AA P LR PE + P
Sbjct: 846 KALEN----------SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 895
Query: 2123 SSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLD 2182
+ T ++ ++ TQD T L AP + + +
Sbjct: 896 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 955
Query: 2183 LRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPG 2242
+ P + P D ++ + +P+P K P P+ T
Sbjct: 956 IMNKPEET-AKPKDRATNSKAT--------TPKPQK------------PTKAPKKPTST- 993
Query: 2243 HSRSAVYPLLYRDGEQTEPSRMGSKSP--GNTSQPPAFFSKLTESNSAMVKSKKQEINKK 2300
+ P + + P +M S P TS+ + T + SK E+N K
Sbjct: 994 -KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPK 1052
Score = 51.6 bits (122), Expect = 1e-05
Identities = 80/352 (22%), Positives = 125/352 (35%), Gaps = 56/352 (15%)
Query: 735 ECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPP-TPPPEDIPAP 793
E + T +S T P+P T K+T PK PA P P P TPPP
Sbjct: 760 ELAPTTTKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 817
Query: 794 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853
T T T +P + P SA P E +E K PAA + +
Sbjct: 818 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV-------PTTKTPAATKPEM 870
Query: 854 DTGKAEEPVKSECTEEAEEGPAKGK----DAEAAEATAEGALKAEKKEGGSG-------- 901
T ++ + + E A K A E T E + A + S
Sbjct: 871 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 930
Query: 902 RATTAKSSG-APQDSDSSATCSADEV-----DEAEGGDK---NRLLSPRPSLLTPTGDPR 952
+ TT K++ AP+ + + T + E+ + A+ D+ ++ +P+P PT P+
Sbjct: 931 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ--KPTKAPK 988
Query: 953 ANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQ 1012
S +KP + ++++ K PR+ T P P + +
Sbjct: 989 KPTSTKKPKTMPRVRK---------PKTTPTPRK---MTSTMPELNPTSRIAEAMLQTTT 1036
Query: 1013 QPGSSPRGKSRSPAPPAD----KEAEKP-------VFFPAFAAEAQKLPGDP 1053
+P +P K P ++ E E P VF P + LP P
Sbjct: 1037 RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVP 1088
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 112 bits (281), Expect = 4e-24
Identities = 168/732 (22%), Positives = 249/732 (34%), Gaps = 99/732 (13%)
Query: 495 QQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKE-EEKPEVENDKEDLLKEKT--- 550
++ + Q+ SS K + K A +E ++K +V+++K++ K+K
Sbjct: 156 EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPK 215
Query: 551 -----DDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ-SAEL 604
+ SG DN + + T +++ +IT A N ++ P +++
Sbjct: 216 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNSDTSKE 273
Query: 605 ASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDE 664
S+ +N+ + +E T K G+ + A+ S + K+ K
Sbjct: 274 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK------- 326
Query: 665 ILQQHKLKME---KERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEA 721
+L + K E K K+ P E A+ P +E + + E A
Sbjct: 327 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTP----KEPTPTTIKSAPTTPKEPA 382
Query: 722 EALHASGNEVPRGECSGPATVNNSSDTESIPSPHT--EAAKDTGQNGP------------ 767
S P+ E + T + T P+P T E A T ++ P
Sbjct: 383 PTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 441
Query: 768 KPPATLGADGPPPGP----PTPPPEDIPAPTEPTPASEATGAPTPP--PAPPSPSAPPPV 821
KP T + P P PT P E P EP P + APT P PAP +P P P
Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501
Query: 822 VPKE------EKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPA 875
PKE ++ T P + P +E A T K+ E + + PA
Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 561
Query: 876 KGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKN 935
E A T + KE A T AP + A + E
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKE----PAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPK 614
Query: 936 RLLSPRPSLLTPTGDPR-ANASPQKPLDLKQLKQRAAAIP--PIVTKVHEP--------- 983
P LTPT + A +P+KP ++ A P P T EP
Sbjct: 615 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-EELAPTTPEEPTPTTPEEPAPTTPKAAA 673
Query: 984 ---PREDA--APTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVF 1038
P+E A P +PAP P P P+ AP P + + PAP K+
Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK------ 727
Query: 1039 FPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDT 1098
PA A +P T P P P+ +P P P+ P P P T
Sbjct: 728 -PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT-----PKEPAPTTPKGT 781
Query: 1099 ARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMG 1158
A P T+ P P P L + P + AP P
Sbjct: 782 A------PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-- 833
Query: 1159 LPLPMDPKKLAP 1170
P P PKK AP
Sbjct: 834 -PAPTTPKKPAP 844
Score = 95.9 bits (237), Expect = 4e-19
Identities = 170/727 (23%), Positives = 245/727 (33%), Gaps = 159/727 (21%)
Query: 617 EEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKE 676
E E T + + E+ + S+ + S T+ + K+ + R+ Q KLK++
Sbjct: 150 ESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRE------LQKKLKVKDN 203
Query: 677 RNARRKKKKAPAAASEEAAFPPVVED---------------------------------- 702
+ R KKK P PPVV++
Sbjct: 204 KKNRTKKKPTPK--------PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA 255
Query: 703 -------------EEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTE 749
+ + + ++ N+E VE E + + G ++ +T+
Sbjct: 256 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN----KQTSTDGKEKTTSAKETQ 311
Query: 750 SI-----------------PSPHTEAA---------KDTGQNGPKPPATLGADGPPP--- 780
SI P+P E K+ PK PA+ P P
Sbjct: 312 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 371
Query: 781 -GPPTPPPEDIPAPTEPTPASEATGAP--TPPPAPPSPSAPPPVVPKEEKEEETAAAP-- 835
PT P E P T+ P + AP T PAP +P P P KE T +AP
Sbjct: 372 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 431
Query: 836 PVEEG------------EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAA 883
P E +E P +E T K P E + PA + A
Sbjct: 432 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491
Query: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEV--DEAEGGDKNRLLSPR 941
T + KE + T S P++ + T SA + A K+ +P+
Sbjct: 492 PTTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 550
Query: 942 PSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEP----PREDAAPT--KPAP 995
T T +P A +P++P K P T EP P+E A T KPAP
Sbjct: 551 EPSPTTTKEP-APTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPAPTTTKKPAP 602
Query: 996 PAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPP---ADKEAEKPVFFPAFAAE-AQKLPG 1051
P P P+ AP P K +P P A EKP P E A P
Sbjct: 603 TTPKEPAPTTPKETAPTTP------KKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPE 654
Query: 1052 DPPCWTSGLPFPVPPREVIKASPHAPDPSA-FSYAP--PGHPLPLGLHDTARPVLPR--- 1105
+P T P P P+ +P P P+ AP P P P +TA P P+
Sbjct: 655 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA-PTTPKGTA 713
Query: 1106 PPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDP 1165
P T+ P P ++ K P+ E + S P K P T P P P
Sbjct: 714 PTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG-TAPTTPKEPAPTTP 770
Query: 1166 KKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPG-GSITKGIPSTRV 1224
K+ AP +P+G A PT + + A + G S T P+
Sbjct: 771 KEPAP--------TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822
Query: 1225 PSDSAIT 1231
P ++A T
Sbjct: 823 PKETAPT 829
Score = 93.6 bits (231), Expect = 2e-18
Identities = 103/394 (26%), Positives = 130/394 (32%), Gaps = 65/394 (16%)
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEP-- 796
P T ++ T P+P T + T P P T P P P PAPT P
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583
Query: 797 ---TPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853
T E T PAP +P P P PK ETA P ++ P E+LA
Sbjct: 584 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK-----ETAPTTP----KKLTPTTPEKLAP 634
Query: 854 DTGKAEEP-VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAP 912
T + P E E P E A T + A KE A T AP
Sbjct: 635 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPKEPAP 690
Query: 913 QDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAA 972
A + E +P+ + T +P A +P+KP K+L
Sbjct: 691 TTPKEPAPTTPKETAPT---------TPKGTAPTTLKEP-APTTPKKPAP-KELAPTTTK 739
Query: 973 IPPIVTKVHEPPREDAAPTKP---APPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPA 1029
P T + APT P AP P P P+ AP P + + PAP
Sbjct: 740 EPTSTT------CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 793
Query: 1030 DKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGH 1089
K+ PA A P TS P P P+E +P P P+
Sbjct: 794 PKK-------PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT-------- 838
Query: 1090 PLPLGLHDTARPVLPRPPTISNPPPLISSAKHPS 1123
P P P T PPP S P+
Sbjct: 839 -----------PKKPAPTTPETPPPTTSEVSTPT 861
Score = 71.2 bits (173), Expect = 1e-11
Identities = 123/544 (22%), Positives = 171/544 (31%), Gaps = 109/544 (20%)
Query: 783 PTPPPEDIPAPTEPTPASEATGAPTP-PPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGE 841
PT PP AP P+ AS+ + T P PP+ V+ EE EE + V E +
Sbjct: 110 PTSPPSSKKAP-PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHS----VSENQ 164
Query: 842 EQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKD-----------------AEAAE 884
E ++ + T + + K+ + K KD EA
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 224
Query: 885 ATAEGALKA---------EKKEGGSGRATTAK----SSGAPQDSDSS------------- 918
G K K S + TTAK P +SD+S
Sbjct: 225 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 284
Query: 919 ---ATCSADEVDEAEGGDKNR----------------------LLSPRPSLLTPTGDPRA 953
T + ++ +G +K L P P T T P A
Sbjct: 285 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-A 343
Query: 954 NASPQKPLDLKQLKQRAAAIP--PIVTKVHEPPREDAAP----TKPAPPAPPPPQNLQPE 1007
+P++P K+ A+ P P T + P P TK AP P P +
Sbjct: 344 LTTPKEPTPTTP-KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 1008 SDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPR 1067
AP P ++ PAP K A P A P P T P P P+
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-----APTTPKKPAPTTPKEPAPTTPK 457
Query: 1068 EVIKASPHAPDPSAFSYAP--PGHPLPLGLHDTA--RPVLPRPPTISNPPPLISSAKHPS 1123
E +P P P+ AP P P P A P P P T P P + P+
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 517
Query: 1124 VLERQIGAISQGMSVQLHVPYSEHAK-APV-----GPVTMGLPLPMDPKKLAPFSGVKQE 1177
+ ++ P K AP P T P P PK+ AP + K
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 577
Query: 1178 QLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSIT 1237
+P+ A PT + T P+ P ++A T +T
Sbjct: 578 PTTPKEPAPTTPKEPAPTTTKKP------------APTTPKEPAPTTPKETAPTTPKKLT 625
Query: 1238 HGTP 1241
TP
Sbjct: 626 PTTP 629
Score = 63.5 bits (153), Expect = 2e-09
Identities = 110/504 (21%), Positives = 159/504 (31%), Gaps = 82/504 (16%)
Query: 1745 PHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERE 1804
P P P P T + P P P + + + PT KP T+ E
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499
Query: 1805 RDRDRERDRDREREKSILT----STTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPAS 1860
+E +E S T + TT + AP T++ + ++ S P +
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT---TKEPAPTTTKSAPTTPKEPSPTT 556
Query: 1861 HSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATF 1920
+P P + P+ T + T + PT + + ++P PA T
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPT----TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 612
Query: 1921 PPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV--------------ARPERPRADTGHAF 1966
P T L P + P K AP PE P T A
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672
Query: 1967 L----AKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIART-PAKNLAPHHASPDPPAP 2021
+P + EPA P+ EP P P + T T P P +P PAP
Sbjct: 673 APNTPKEPAPTTPKEPA--PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Query: 2022 PASASDPHREKTQS---KPFSIQELELRSLGYHGSSYSPEGVEPVSP-------VSSPSL 2071
A +E T + KP + +P+G P +P P+
Sbjct: 731 KELAPTTTKEPTSTTCDKP---------------APTTPKGTAPTTPKEPAPTTPKEPAP 775
Query: 2072 THDKG-LPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHL----RPLPESQPSSSPL 2126
T KG P L+E PK+P P +L P +P P + ++P
Sbjct: 776 TTPKGTAPTTLKE------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829
Query: 2127 -----LQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVL 2181
T P T SEV T T+ P ++ P S P L
Sbjct: 830 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---------PTTIHKSPDESTPEL 880
Query: 2182 DLRRPPSDLYLPPPDHGAPARGSP 2205
P L P + G P +P
Sbjct: 881 SAEPTPKALENSPKEPGVPTTKTP 904
Score = 61.2 bits (147), Expect = 1e-08
Identities = 84/359 (23%), Positives = 128/359 (35%), Gaps = 52/359 (14%)
Query: 732 PRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIP 791
P+G + P T+ + T +P A K+ K P + +D P PT P E P
Sbjct: 778 PKG--TAPTTLKEPAPT----TPKKPAPKELAPTTTKGPTSTTSDKP---APTTPKETAP 828
Query: 792 -APTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEE----GEEQKPP 846
P EP P + APT P PP P+ P KE T P E E P
Sbjct: 829 TTPKEPAPTTPKKPAPTTPETPP-PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 887
Query: 847 AAE----ELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGR 902
A E E V T K K E T A++ + +D T A K K+
Sbjct: 888 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE-RDLRTTPETTTAAPKMTKE-----T 941
Query: 903 ATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLD 962
ATT + + ++S T + +V D +L T T P+ +
Sbjct: 942 ATTTEKT-----TESKITATTTQVTSTTTQDTTPF--KITTLKTTTLAPKVTTT------ 988
Query: 963 LKQLKQRAAAIPPIVTKVHE--PPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRG 1020
++ I+ K E P++ A +K P P P + + ++P + PR
Sbjct: 989 -----KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRV 1043
Query: 1021 KSRSPAP-PADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPD 1078
+ P P + P P L T+ P P ++++ +P + D
Sbjct: 1044 RKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ------TTTRPNQTPNSKLVEVNPKSED 1096
Score = 57.0 bits (136), Expect = 2e-07
Identities = 89/395 (22%), Positives = 141/395 (35%), Gaps = 51/395 (12%)
Query: 1748 PVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDR 1807
P L P TP T + + P P P + + S+P +P P PTTT S+
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIK--SAPTTPKEPA----PTTTKSAP---TT 392
Query: 1808 DRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQH 1867
+E +E + TT E AP T++ + ++ S P +
Sbjct: 393 PKEPAPTTTKEPA---PTTPKEPAP---TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 1868 SPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFP--PATH 1925
+P P + P+ T + T EP+ PT + + ++P +PA T P PA
Sbjct: 447 TPKEPAPTTPKEPTPT----TPKEPAPTTKEPA-PTTPKEPAPTAPKKPAPTTPKEPAPT 501
Query: 1926 CPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKG 1985
P EP + P P+ P T K + EPA + +K
Sbjct: 502 TP------------KEPAPTTTKEPSPTTPKEPAPTT-----TKSAPTTTKEPAPTTTKS 544
Query: 1986 SEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAP-------PASASDPHREKTQSKPF 2038
+ P P + A T K AP +P PAP P + +P T+
Sbjct: 545 APTTPKEPSPTTTKEPAPTTPKEPAP--TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 602
Query: 2039 SIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLE--GELRPK 2096
+ + + + +P+ + P +P T +K P EEL + E P+
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 662
Query: 2097 QPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAP 2131
+P P A + P P P + +P P
Sbjct: 663 EPAPTTPKAAAPNTPK-EPAPTTPKEPAPTTPKEP 696
Score = 56.2 bits (134), Expect = 4e-07
Identities = 155/780 (19%), Positives = 236/780 (30%), Gaps = 127/780 (16%)
Query: 1565 SPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRG 1624
+P TT+EP P + ++ T + K P T P+ P P +P E
Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEP---- 451
Query: 1625 VSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPN------PTYPHLYPPYLIR 1678
P PT+ P A P+ AP PT P P +
Sbjct: 452 -------APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 1679 GYPDTAALENRQTIINDYI-TSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRG 1737
T E T + T+ + A +P+E S P
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-- 562
Query: 1738 IIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLT-KPT 1796
P P P P T + P P P +++ +P +P P T K T
Sbjct: 563 -----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK-KPAPTTPKEPAPTTPKET 616
Query: 1797 TTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIW----RPGTEQSSGSSGSSGGGG 1852
++ ++ E+ EK TT E AP P T + +
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 674
Query: 1853 GSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSS 1912
+ PA +P P + P+ T T + + PT L+ + ++
Sbjct: 675 NTPKEPA------PTTPKEPAPTTPKEPAPTTPKETAP----TTPKGTAPTTLKEPAPTT 724
Query: 1913 PVRPA--ATFPPATHCPLGGTLDGVYPTLME---PVLLPKEAPRVARPERPRADTGHA-- 1965
P +PA P T P T D PT + P + AP + P G A
Sbjct: 725 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784
Query: 1966 -------FLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDP 2018
K PA L P ++ S P + T TP + P +P
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE---PAPTTPKK 841
Query: 2019 PAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLP 2078
PAP + P S P + +E P + S+P L+ + P
Sbjct: 842 PAPTTPETPPPTTSEVSTPTTTKE--------------PTTIHKSPDESTPELSAEP-TP 886
Query: 2079 KHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPH-------------LRPLPE---SQPS 2122
K LE PK+PG AA P LR PE + P
Sbjct: 887 KALEN----------SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 936
Query: 2123 SSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLD 2182
+ T ++ ++ TQD T L AP + + +
Sbjct: 937 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 996
Query: 2183 LRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPG 2242
+ P + P D ++ + +P+P K P P+ T
Sbjct: 997 IMNKPEET-AKPKDRATNSKAT--------TPKPQK------------PTKAPKKPTST- 1034
Query: 2243 HSRSAVYPLLYRDGEQTEPSRMGSKSP--GNTSQPPAFFSKLTESNSAMVKSKKQEINKK 2300
+ P + + P +M S P TS+ + T + SK E+N K
Sbjct: 1035 -KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPK 1093
Score = 51.6 bits (122), Expect = 1e-05
Identities = 80/352 (22%), Positives = 125/352 (35%), Gaps = 56/352 (15%)
Query: 735 ECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPP-TPPPEDIPAP 793
E + T +S T P+P T K+T PK PA P P P TPPP
Sbjct: 801 ELAPTTTKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 858
Query: 794 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853
T T T +P + P SA P E +E K PAA + +
Sbjct: 859 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV-------PTTKTPAATKPEM 911
Query: 854 DTGKAEEPVKSECTEEAEEGPAKGK----DAEAAEATAEGALKAEKKEGGSG-------- 901
T ++ + + E A K A E T E + A + S
Sbjct: 912 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 971
Query: 902 RATTAKSSG-APQDSDSSATCSADEV-----DEAEGGDK---NRLLSPRPSLLTPTGDPR 952
+ TT K++ AP+ + + T + E+ + A+ D+ ++ +P+P PT P+
Sbjct: 972 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ--KPTKAPK 1029
Query: 953 ANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQ 1012
S +KP + ++++ K PR+ T P P + +
Sbjct: 1030 KPTSTKKPKTMPRVRK---------PKTTPTPRK---MTSTMPELNPTSRIAEAMLQTTT 1077
Query: 1013 QPGSSPRGKSRSPAPPAD----KEAEKP-------VFFPAFAAEAQKLPGDP 1053
+P +P K P ++ E E P VF P + LP P
Sbjct: 1078 RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVP 1129
>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
Length = 553
Score = 112 bits (280), Expect = 5e-24
Identities = 107/413 (25%), Positives = 166/413 (40%), Gaps = 55/413 (13%)
Query: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
W+ ++K F + F H K+F I L KT+A V YYY KK + SL+ R R
Sbjct: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 203
Query: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDL------ 545
K + Q ++ PM + + +KE +KE E+ V+ K L
Sbjct: 204 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQP---VQTSKIGLGRREYQ 260
Query: 546 --------LKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANS 592
+ K G +++ VA S AN+ R+ + R + N
Sbjct: 261 SLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQV 320
Query: 593 EEAITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVS 647
A+ + + + ES+ RWT EE A +G+ ++G+++ AIA ++G+KTV
Sbjct: 321 NSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVG 380
Query: 648 QCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEA 707
Q KNF+ NY++R NL+E+LQ+ E E+ + A E + V
Sbjct: 381 QVKNFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------P 429
Query: 708 SGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIP--SPHTEAAKDTGQN 765
SG S +EEE + +A G P + T ++ + P P AA +
Sbjct: 430 SGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQ 489
Query: 766 GP---------KPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP 809
P +P TL PP P P +P P P G PP
Sbjct: 490 PPPLQQQARFIQPRPTL---NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 539
Score = 38.1 bits (87), Expect = 0.11
Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 6/118 (5%)
Query: 1002 QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLP 1061
Q Q + G + S P+ + E E+ A +A + G P S P
Sbjct: 406 QGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPSSTP 460
Query: 1062 FPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1119
P P + P P+ AP H P L AR + PRP PPPLI A
Sbjct: 461 TPTAPIATLNQPPPLLRPT-LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPA 517
Score = 32.7 bits (73), Expect = 4.6
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 13/138 (9%)
Query: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPS 943
E AE +A + + T +S P S DE +EA+ R L P P
Sbjct: 401 EWEAEQGTQASNGDASTLGEETKSASNVPSGK------STDEEEEAQTPQAPRTLGPSPP 454
Query: 944 LLTPTGDPRAN-ASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA-PPPP 1001
+ T P A A+ +P L + AA P + + P ++ A +P P PPP
Sbjct: 455 APSSTPTPTAPIATLNQPPPLLRPTLPAA---PALHRQPPPLQQQARFIQPRPTLNQPPP 511
Query: 1002 QNLQPESDAPQQPGSSPR 1019
++P + P P +PR
Sbjct: 512 PLIRPANSMP--PRLNPR 527
>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
Length = 495
Score = 112 bits (280), Expect = 5e-24
Identities = 107/413 (25%), Positives = 166/413 (40%), Gaps = 55/413 (13%)
Query: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
W+ ++K F + F H K+F I L KT+A V YYY KK + SL+ R R
Sbjct: 89 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 145
Query: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDL------ 545
K + Q ++ PM + + +KE +KE E+ V+ K L
Sbjct: 146 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQP---VQTSKIGLGRREYQ 202
Query: 546 --------LKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANS 592
+ K G +++ VA S AN+ R+ + R + N
Sbjct: 203 SLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQV 262
Query: 593 EEAITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVS 647
A+ + + + ES+ RWT EE A +G+ ++G+++ AIA ++G+KTV
Sbjct: 263 NSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVG 322
Query: 648 QCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEA 707
Q KNF+ NY++R NL+E+LQ+ E E+ + A E + V
Sbjct: 323 QVKNFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------P 371
Query: 708 SGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIP--SPHTEAAKDTGQN 765
SG S +EEE + +A G P + T ++ + P P AA +
Sbjct: 372 SGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQ 431
Query: 766 GP---------KPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP 809
P +P TL PP P P +P P P G PP
Sbjct: 432 PPPLQQQARFIQPRPTL---NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 481
Score = 38.1 bits (87), Expect = 0.11
Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 6/118 (5%)
Query: 1002 QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLP 1061
Q Q + G + S P+ + E E+ A +A + G P S P
Sbjct: 348 QGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPSSTP 402
Query: 1062 FPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1119
P P + P P+ AP H P L AR + PRP PPPLI A
Sbjct: 403 TPTAPIATLNQPPPLLRPT-LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPA 459
Score = 32.7 bits (73), Expect = 4.6
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 13/138 (9%)
Query: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPS 943
E AE +A + + T +S P S DE +EA+ R L P P
Sbjct: 343 EWEAEQGTQASNGDASTLGEETKSASNVPSGK------STDEEEEAQTPQAPRTLGPSPP 396
Query: 944 LLTPTGDPRAN-ASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA-PPPP 1001
+ T P A A+ +P L + AA P + + P ++ A +P P PPP
Sbjct: 397 APSSTPTPTAPIATLNQPPPLLRPTLPAA---PALHRQPPPLQQQARFIQPRPTLNQPPP 453
Query: 1002 QNLQPESDAPQQPGSSPR 1019
++P + P P +PR
Sbjct: 454 PLIRPANSMP--PRLNPR 469
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 106 bits (265), Expect = 3e-22
Identities = 165/700 (23%), Positives = 234/700 (33%), Gaps = 101/700 (14%)
Query: 518 EEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGR 577
E KD K K + +K KP V ++ SG DN + + T +++
Sbjct: 65 EVKDNK-KNRTKKKPTPKPPVVDEAG----------SGLDNGDFKVTTPDTSTTQHNKVS 113
Query: 578 RKGRITRSMANEANSEEAITPQQ-SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSA 636
+IT A N ++ P +++ S+ +N+ + +E T K G+ +
Sbjct: 114 TSPKITT--AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTT 171
Query: 637 IARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKME---KERNARRKKKKAPAAASEE 693
A+ S + K+ K +L + K E K K+ P E
Sbjct: 172 SAKETQSIEKTSAKDLAPTSK-------VLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 224
Query: 694 AAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPS 753
A+ P +E + + E A S P+ E + T + T P+
Sbjct: 225 ASTTP----KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPA 279
Query: 754 PHT--EAAKDTGQNGP------------KPPATLGADGPPPGP----PTPPPEDIPAPTE 795
P T E A T ++ P KP T + P P PT P E P E
Sbjct: 280 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE 339
Query: 796 PTPASEATGAPTPP--PAPPSPSAPPPVVPKE------EKEEETAAAPPVEEGEEQKPPA 847
P P + APT P PAP +P P P PKE ++ T P + P
Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399
Query: 848 AEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAK 907
+E A T K+ E + + PA E A T + KE A T
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE----PAPTTP 455
Query: 908 SSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPR-ANASPQKPLDLKQL 966
AP + A + E P LTPT + A +P+KP
Sbjct: 456 KEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP- 511
Query: 967 KQRAAAIP--PIVTKVHEP------------PREDA--APTKPAPPAPPPPQNLQPESDA 1010
++ A P P T EP P+E A P +PAP P P P+ A
Sbjct: 512 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571
Query: 1011 PQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVI 1070
P P + + PAP K+ PA A +P T P P P+
Sbjct: 572 PTTPKGTAPTTLKEPAPTTPKK-------PAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624
Query: 1071 KASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIG 1130
+P P P+ P P P TA P T+ P P P L
Sbjct: 625 PTTPKEPAPTT-----PKEPAPTTPKGTA------PTTLKEPAPTTPKKPAPKELAPTTT 673
Query: 1131 AISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAP 1170
+ P + AP P P P PKK AP
Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKE---PAPTTPKKPAP 710
Score = 105 bits (263), Expect = 4e-22
Identities = 139/512 (27%), Positives = 187/512 (36%), Gaps = 69/512 (13%)
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTP 798
P T+ ++ T P+P T + T PK PA P P T P E P T+
Sbjct: 234 PTTIKSAPTTPKEPAPTTTKSAPTT---PKEPAPTTTKEPAP---TTPKEPAPTTTKEPA 287
Query: 799 ASEATGAPTPP--PAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTG 856
+ APT P PAP +P P P PKE T P ++ P +E A T
Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Query: 857 KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSD 916
K P A + PA E A T + KE + T AP +
Sbjct: 346 KEPAPT-------APKKPAPTTPKEPAPTTPKEPAPTTTKE----PSPTTPKEPAPTTTK 394
Query: 917 SSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPI 976
S+ T + + A K+ +P+ T T +P A +P++P K P
Sbjct: 395 SAPTTTK---EPAPTTTKSAPTTPKEPSPTTTKEP-APTTPKEPAPTTPKK-------PA 443
Query: 977 VTKVHEP----PREDAAPT--KPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPP-- 1028
T EP P+E A T KPAP P P P+ AP P K +P P
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP------KKLTPTTPEK 497
Query: 1029 -ADKEAEKPVFFPAFAAE-AQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSA-FSYA 1085
A EKP P E A P +P T P P P+ +P P P+ A
Sbjct: 498 LAPTTPEKPA--PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 555
Query: 1086 P--PGHPLPLGLHDTARPVLPR---PPTISNPPPLISSAKHPSVLERQIGAISQGMSVQL 1140
P P P P +TA P P+ P T+ P P ++ K P+ E + S
Sbjct: 556 PTTPKEPAPTTPKETA-PTTPKGTAPTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTC 612
Query: 1141 HVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEAS 1200
P K P T P P PK+ AP +P+G A PT +
Sbjct: 613 DKPAPTTPKG-TAPTTPKEPAPTTPKEPAP--------TTPKGTAPTTLKEPAPTTPKKP 663
Query: 1201 VLRGTALGSVPG-GSITKGIPSTRVPSDSAIT 1231
+ A + G S T P+ P ++A T
Sbjct: 664 APKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695
Score = 93.6 bits (231), Expect = 2e-18
Identities = 103/394 (26%), Positives = 130/394 (32%), Gaps = 65/394 (16%)
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEP-- 796
P T ++ T P+P T + T P P T P P P PAPT P
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449
Query: 797 ---TPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853
T E T PAP +P P P PK ETA P ++ P E+LA
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK-----ETAPTTP----KKLTPTTPEKLAP 500
Query: 854 DTGKAEEP-VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAP 912
T + P E E P E A T + A KE A T AP
Sbjct: 501 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPKEPAP 556
Query: 913 QDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAA 972
A + E +P+ + T +P A +P+KP K+L
Sbjct: 557 TTPKEPAPTTPKETAPT---------TPKGTAPTTLKEP-APTTPKKPAP-KELAPTTTK 605
Query: 973 IPPIVTKVHEPPREDAAPTKP---APPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPA 1029
P T + APT P AP P P P+ AP P + + PAP
Sbjct: 606 EPTSTT------CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659
Query: 1030 DKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGH 1089
K+ PA A P TS P P P+E +P P P+
Sbjct: 660 PKK-------PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT-------- 704
Query: 1090 PLPLGLHDTARPVLPRPPTISNPPPLISSAKHPS 1123
P P P T PPP S P+
Sbjct: 705 -----------PKKPAPTTPETPPPTTSEVSTPT 727
Score = 63.5 bits (153), Expect = 2e-09
Identities = 110/504 (21%), Positives = 159/504 (31%), Gaps = 82/504 (16%)
Query: 1745 PHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERE 1804
P P P P T + P P P + + + PT KP T+ E
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365
Query: 1805 RDRDRERDRDREREKSILT----STTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPAS 1860
+E +E S T + TT + AP T++ + ++ S P +
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT---TKEPAPTTTKSAPTTPKEPSPTT 422
Query: 1861 HSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATF 1920
+P P + P+ T + T + PT + + ++P PA T
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPT----TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 478
Query: 1921 PPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV--------------ARPERPRADTGHAF 1966
P T L P + P K AP PE P T A
Sbjct: 479 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 538
Query: 1967 L----AKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIART-PAKNLAPHHASPDPPAP 2021
+P + EPA P+ EP P P + T T P P +P PAP
Sbjct: 539 APNTPKEPAPTTPKEPA--PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Query: 2022 PASASDPHREKTQS---KPFSIQELELRSLGYHGSSYSPEGVEPVSP-------VSSPSL 2071
A +E T + KP + +P+G P +P P+
Sbjct: 597 KELAPTTTKEPTSTTCDKP---------------APTTPKGTAPTTPKEPAPTTPKEPAP 641
Query: 2072 THDKG-LPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHL----RPLPESQPSSSPL 2126
T KG P L+E PK+P P +L P +P P + ++P
Sbjct: 642 TTPKGTAPTTLKE------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695
Query: 2127 -----LQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVL 2181
T P T SEV T T+ P ++ P S P L
Sbjct: 696 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---------PTTIHKSPDESTPEL 746
Query: 2182 DLRRPPSDLYLPPPDHGAPARGSP 2205
P L P + G P +P
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTP 770
Score = 61.2 bits (147), Expect = 1e-08
Identities = 84/359 (23%), Positives = 128/359 (35%), Gaps = 52/359 (14%)
Query: 732 PRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIP 791
P+G + P T+ + T +P A K+ K P + +D P PT P E P
Sbjct: 644 PKG--TAPTTLKEPAPT----TPKKPAPKELAPTTTKGPTSTTSDKP---APTTPKETAP 694
Query: 792 -APTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEE----GEEQKPP 846
P EP P + APT P PP P+ P KE T P E E P
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPP-PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 753
Query: 847 AAE----ELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGR 902
A E E V T K K E T A++ + +D T A K K+
Sbjct: 754 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE-RDLRTTPETTTAAPKMTKE-----T 807
Query: 903 ATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLD 962
ATT + + ++S T + +V D +L T T P+ +
Sbjct: 808 ATTTEKT-----TESKITATTTQVTSTTTQDTTPF--KITTLKTTTLAPKVTTT------ 854
Query: 963 LKQLKQRAAAIPPIVTKVHE--PPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRG 1020
++ I+ K E P++ A +K P P P + + ++P + PR
Sbjct: 855 -----KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRV 909
Query: 1021 KSRSPAP-PADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPD 1078
+ P P + P P L T+ P P ++++ +P + D
Sbjct: 910 RKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ------TTTRPNQTPNSKLVEVNPKSED 962
Score = 57.0 bits (136), Expect = 2e-07
Identities = 89/395 (22%), Positives = 141/395 (35%), Gaps = 51/395 (12%)
Query: 1748 PVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDR 1807
P L P TP T + + P P P + + S+P +P P PTTT S+
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIK--SAPTTPKEPA----PTTTKSAP---TT 258
Query: 1808 DRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQH 1867
+E +E + TT E AP T++ + ++ S P +
Sbjct: 259 PKEPAPTTTKEPA---PTTPKEPAP---TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312
Query: 1868 SPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFP--PATH 1925
+P P + P+ T + T EP+ PT + + ++P +PA T P PA
Sbjct: 313 TPKEPAPTTPKEPTPT----TPKEPAPTTKEPA-PTTPKEPAPTAPKKPAPTTPKEPAPT 367
Query: 1926 CPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKG 1985
P EP + P P+ P T K + EPA + +K
Sbjct: 368 TP------------KEPAPTTTKEPSPTTPKEPAPTT-----TKSAPTTTKEPAPTTTKS 410
Query: 1986 SEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAP-------PASASDPHREKTQSKPF 2038
+ P P + A T K AP +P PAP P + +P T+
Sbjct: 411 APTTPKEPSPTTTKEPAPTTPKEPAP--TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 468
Query: 2039 SIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLE--GELRPK 2096
+ + + + +P+ + P +P T +K P EEL + E P+
Sbjct: 469 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 528
Query: 2097 QPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAP 2131
+P P A + P P P + +P P
Sbjct: 529 EPAPTTPKAAAPNTPK-EPAPTTPKEPAPTTPKEP 562
Score = 56.2 bits (134), Expect = 4e-07
Identities = 155/780 (19%), Positives = 236/780 (30%), Gaps = 127/780 (16%)
Query: 1565 SPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRG 1624
+P TT+EP P + ++ T + K P T P+ P P +P E
Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEP---- 317
Query: 1625 VSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPN------PTYPHLYPPYLIR 1678
P PT+ P A P+ AP PT P P +
Sbjct: 318 -------APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 370
Query: 1679 GYPDTAALENRQTIINDYI-TSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRG 1737
T E T + T+ + A +P+E S P
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-- 428
Query: 1738 IIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLT-KPT 1796
P P P P T + P P P +++ +P +P P T K T
Sbjct: 429 -----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK-KPAPTTPKEPAPTTPKET 482
Query: 1797 TTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIW----RPGTEQSSGSSGSSGGGG 1852
++ ++ E+ EK TT E AP P T + +
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 540
Query: 1853 GSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSS 1912
+ PA +P P + P+ T T + + PT L+ + ++
Sbjct: 541 NTPKEPA------PTTPKEPAPTTPKEPAPTTPKETAP----TTPKGTAPTTLKEPAPTT 590
Query: 1913 PVRPA--ATFPPATHCPLGGTLDGVYPTLME---PVLLPKEAPRVARPERPRADTGHA-- 1965
P +PA P T P T D PT + P + AP + P G A
Sbjct: 591 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650
Query: 1966 -------FLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDP 2018
K PA L P ++ S P + T TP + P +P
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE---PAPTTPKK 707
Query: 2019 PAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLP 2078
PAP + P S P + +E P + S+P L+ + P
Sbjct: 708 PAPTTPETPPPTTSEVSTPTTTKE--------------PTTIHKSPDESTPELSAEP-TP 752
Query: 2079 KHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPH-------------LRPLPE---SQPS 2122
K LE PK+PG AA P LR PE + P
Sbjct: 753 KALEN----------SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 802
Query: 2123 SSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLD 2182
+ T ++ ++ TQD T L AP + + +
Sbjct: 803 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 862
Query: 2183 LRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPG 2242
+ P + P D ++ + +P+P K P P+ T
Sbjct: 863 IMNKPEET-AKPKDRATNSKAT--------TPKPQK------------PTKAPKKPTST- 900
Query: 2243 HSRSAVYPLLYRDGEQTEPSRMGSKSP--GNTSQPPAFFSKLTESNSAMVKSKKQEINKK 2300
+ P + + P +M S P TS+ + T + SK E+N K
Sbjct: 901 -KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPK 959
Score = 51.6 bits (122), Expect = 1e-05
Identities = 80/352 (22%), Positives = 125/352 (35%), Gaps = 56/352 (15%)
Query: 735 ECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPP-TPPPEDIPAP 793
E + T +S T P+P T K+T PK PA P P P TPPP
Sbjct: 667 ELAPTTTKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 794 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853
T T T +P + P SA P E +E K PAA + +
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV-------PTTKTPAATKPEM 777
Query: 854 DTGKAEEPVKSECTEEAEEGPAKGK----DAEAAEATAEGALKAEKKEGGSG-------- 901
T ++ + + E A K A E T E + A + S
Sbjct: 778 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 837
Query: 902 RATTAKSSG-APQDSDSSATCSADEV-----DEAEGGDK---NRLLSPRPSLLTPTGDPR 952
+ TT K++ AP+ + + T + E+ + A+ D+ ++ +P+P PT P+
Sbjct: 838 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ--KPTKAPK 895
Query: 953 ANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQ 1012
S +KP + ++++ K PR+ T P P + +
Sbjct: 896 KPTSTKKPKTMPRVRK---------PKTTPTPRK---MTSTMPELNPTSRIAEAMLQTTT 943
Query: 1013 QPGSSPRGKSRSPAPPAD----KEAEKP-------VFFPAFAAEAQKLPGDP 1053
+P +P K P ++ E E P VF P + LP P
Sbjct: 944 RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVP 995
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 106 bits (265), Expect = 3e-22
Identities = 165/700 (23%), Positives = 234/700 (33%), Gaps = 101/700 (14%)
Query: 518 EEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGR 577
E KD K K + +K KP V ++ SG DN + + T +++
Sbjct: 106 EVKDNK-KNRTKKKPTPKPPVVDEAG----------SGLDNGDFKVTTPDTSTTQHNKVS 154
Query: 578 RKGRITRSMANEANSEEAITPQQ-SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSA 636
+IT A N ++ P +++ S+ +N+ + +E T K G+ +
Sbjct: 155 TSPKITT--AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTT 212
Query: 637 IARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKME---KERNARRKKKKAPAAASEE 693
A+ S + K+ K +L + K E K K+ P E
Sbjct: 213 SAKETQSIEKTSAKDLAPTSK-------VLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 265
Query: 694 AAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPS 753
A+ P +E + + E A S P+ E + T + T P+
Sbjct: 266 ASTTP----KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPA 320
Query: 754 PHT--EAAKDTGQNGP------------KPPATLGADGPPPGP----PTPPPEDIPAPTE 795
P T E A T ++ P KP T + P P PT P E P E
Sbjct: 321 PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKE 380
Query: 796 PTPASEATGAPTPP--PAPPSPSAPPPVVPKE------EKEEETAAAPPVEEGEEQKPPA 847
P P + APT P PAP +P P P PKE ++ T P + P
Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440
Query: 848 AEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAK 907
+E A T K+ E + + PA E A T + KE A T
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE----PAPTTP 496
Query: 908 SSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPR-ANASPQKPLDLKQL 966
AP + A + E P LTPT + A +P+KP
Sbjct: 497 KEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP- 552
Query: 967 KQRAAAIP--PIVTKVHEP------------PREDA--APTKPAPPAPPPPQNLQPESDA 1010
++ A P P T EP P+E A P +PAP P P P+ A
Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612
Query: 1011 PQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVI 1070
P P + + PAP K+ PA A +P T P P P+
Sbjct: 613 PTTPKGTAPTTLKEPAPTTPKK-------PAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665
Query: 1071 KASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIG 1130
+P P P+ P P P TA P T+ P P P L
Sbjct: 666 PTTPKEPAPTT-----PKEPAPTTPKGTA------PTTLKEPAPTTPKKPAPKELAPTTT 714
Query: 1131 AISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAP 1170
+ P + AP P P P PKK AP
Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKE---PAPTTPKKPAP 751
Score = 105 bits (263), Expect = 4e-22
Identities = 139/512 (27%), Positives = 187/512 (36%), Gaps = 69/512 (13%)
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTP 798
P T+ ++ T P+P T + T PK PA P P T P E P T+
Sbjct: 275 PTTIKSAPTTPKEPAPTTTKSAPTT---PKEPAPTTTKEPAP---TTPKEPAPTTTKEPA 328
Query: 799 ASEATGAPTPP--PAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTG 856
+ APT P PAP +P P P PKE T P ++ P +E A T
Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386
Query: 857 KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSD 916
K P A + PA E A T + KE + T AP +
Sbjct: 387 KEPAPT-------APKKPAPTTPKEPAPTTPKEPAPTTTKE----PSPTTPKEPAPTTTK 435
Query: 917 SSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPI 976
S+ T + + A K+ +P+ T T +P A +P++P K P
Sbjct: 436 SAPTTTK---EPAPTTTKSAPTTPKEPSPTTTKEP-APTTPKEPAPTTPKK-------PA 484
Query: 977 VTKVHEP----PREDAAPT--KPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPP-- 1028
T EP P+E A T KPAP P P P+ AP P K +P P
Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP------KKLTPTTPEK 538
Query: 1029 -ADKEAEKPVFFPAFAAE-AQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSA-FSYA 1085
A EKP P E A P +P T P P P+ +P P P+ A
Sbjct: 539 LAPTTPEKPA--PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 596
Query: 1086 P--PGHPLPLGLHDTARPVLPR---PPTISNPPPLISSAKHPSVLERQIGAISQGMSVQL 1140
P P P P +TA P P+ P T+ P P ++ K P+ E + S
Sbjct: 597 PTTPKEPAPTTPKETA-PTTPKGTAPTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTC 653
Query: 1141 HVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEAS 1200
P K P T P P PK+ AP +P+G A PT +
Sbjct: 654 DKPAPTTPKG-TAPTTPKEPAPTTPKEPAP--------TTPKGTAPTTLKEPAPTTPKKP 704
Query: 1201 VLRGTALGSVPG-GSITKGIPSTRVPSDSAIT 1231
+ A + G S T P+ P ++A T
Sbjct: 705 APKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736
Score = 93.6 bits (231), Expect = 2e-18
Identities = 103/394 (26%), Positives = 130/394 (32%), Gaps = 65/394 (16%)
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEP-- 796
P T ++ T P+P T + T P P T P P P PAPT P
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490
Query: 797 ---TPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853
T E T PAP +P P P PK ETA P ++ P E+LA
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK-----ETAPTTP----KKLTPTTPEKLAP 541
Query: 854 DTGKAEEP-VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAP 912
T + P E E P E A T + A KE A T AP
Sbjct: 542 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPKEPAP 597
Query: 913 QDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAA 972
A + E +P+ + T +P A +P+KP K+L
Sbjct: 598 TTPKEPAPTTPKETAPT---------TPKGTAPTTLKEP-APTTPKKPAP-KELAPTTTK 646
Query: 973 IPPIVTKVHEPPREDAAPTKP---APPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPA 1029
P T + APT P AP P P P+ AP P + + PAP
Sbjct: 647 EPTSTT------CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700
Query: 1030 DKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGH 1089
K+ PA A P TS P P P+E +P P P+
Sbjct: 701 PKK-------PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT-------- 745
Query: 1090 PLPLGLHDTARPVLPRPPTISNPPPLISSAKHPS 1123
P P P T PPP S P+
Sbjct: 746 -----------PKKPAPTTPETPPPTTSEVSTPT 768
Score = 63.5 bits (153), Expect = 2e-09
Identities = 110/504 (21%), Positives = 159/504 (31%), Gaps = 82/504 (16%)
Query: 1745 PHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERE 1804
P P P P T + P P P + + + PT KP T+ E
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406
Query: 1805 RDRDRERDRDREREKSILT----STTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPAS 1860
+E +E S T + TT + AP T++ + ++ S P +
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT---TKEPAPTTTKSAPTTPKEPSPTT 463
Query: 1861 HSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATF 1920
+P P + P+ T + T + PT + + ++P PA T
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPT----TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 519
Query: 1921 PPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV--------------ARPERPRADTGHAF 1966
P T L P + P K AP PE P T A
Sbjct: 520 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 579
Query: 1967 L----AKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIART-PAKNLAPHHASPDPPAP 2021
+P + EPA P+ EP P P + T T P P +P PAP
Sbjct: 580 APNTPKEPAPTTPKEPA--PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Query: 2022 PASASDPHREKTQS---KPFSIQELELRSLGYHGSSYSPEGVEPVSP-------VSSPSL 2071
A +E T + KP + +P+G P +P P+
Sbjct: 638 KELAPTTTKEPTSTTCDKP---------------APTTPKGTAPTTPKEPAPTTPKEPAP 682
Query: 2072 THDKG-LPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHL----RPLPESQPSSSPL 2126
T KG P L+E PK+P P +L P +P P + ++P
Sbjct: 683 TTPKGTAPTTLKE------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736
Query: 2127 -----LQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVL 2181
T P T SEV T T+ P ++ P S P L
Sbjct: 737 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---------PTTIHKSPDESTPEL 787
Query: 2182 DLRRPPSDLYLPPPDHGAPARGSP 2205
P L P + G P +P
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTP 811
Score = 61.2 bits (147), Expect = 1e-08
Identities = 84/359 (23%), Positives = 128/359 (35%), Gaps = 52/359 (14%)
Query: 732 PRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIP 791
P+G + P T+ + T +P A K+ K P + +D P PT P E P
Sbjct: 685 PKG--TAPTTLKEPAPT----TPKKPAPKELAPTTTKGPTSTTSDKP---APTTPKETAP 735
Query: 792 -APTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEE----GEEQKPP 846
P EP P + APT P PP P+ P KE T P E E P
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETPP-PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 794
Query: 847 AAE----ELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGR 902
A E E V T K K E T A++ + +D T A K K+
Sbjct: 795 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE-RDLRTTPETTTAAPKMTKE-----T 848
Query: 903 ATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLD 962
ATT + + ++S T + +V D +L T T P+ +
Sbjct: 849 ATTTEKT-----TESKITATTTQVTSTTTQDTTPF--KITTLKTTTLAPKVTTT------ 895
Query: 963 LKQLKQRAAAIPPIVTKVHE--PPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRG 1020
++ I+ K E P++ A +K P P P + + ++P + PR
Sbjct: 896 -----KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRV 950
Query: 1021 KSRSPAP-PADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPD 1078
+ P P + P P L T+ P P ++++ +P + D
Sbjct: 951 RKPKTTPTPRKMTSTMPELNPTSRIAEAMLQ------TTTRPNQTPNSKLVEVNPKSED 1003
Score = 57.0 bits (136), Expect = 2e-07
Identities = 89/395 (22%), Positives = 141/395 (35%), Gaps = 51/395 (12%)
Query: 1748 PVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDR 1807
P L P TP T + + P P P + + S+P +P P PTTT S+
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIK--SAPTTPKEPA----PTTTKSAP---TT 299
Query: 1808 DRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQH 1867
+E +E + TT E AP T++ + ++ S P +
Sbjct: 300 PKEPAPTTTKEPA---PTTPKEPAP---TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353
Query: 1868 SPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFP--PATH 1925
+P P + P+ T + T EP+ PT + + ++P +PA T P PA
Sbjct: 354 TPKEPAPTTPKEPTPT----TPKEPAPTTKEPA-PTTPKEPAPTAPKKPAPTTPKEPAPT 408
Query: 1926 CPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKG 1985
P EP + P P+ P T K + EPA + +K
Sbjct: 409 TP------------KEPAPTTTKEPSPTTPKEPAPTT-----TKSAPTTTKEPAPTTTKS 451
Query: 1986 SEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAP-------PASASDPHREKTQSKPF 2038
+ P P + A T K AP +P PAP P + +P T+
Sbjct: 452 APTTPKEPSPTTTKEPAPTTPKEPAP--TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 509
Query: 2039 SIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLE--GELRPK 2096
+ + + + +P+ + P +P T +K P EEL + E P+
Sbjct: 510 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 569
Query: 2097 QPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAP 2131
+P P A + P P P + +P P
Sbjct: 570 EPAPTTPKAAAPNTPK-EPAPTTPKEPAPTTPKEP 603
Score = 56.2 bits (134), Expect = 4e-07
Identities = 155/780 (19%), Positives = 236/780 (30%), Gaps = 127/780 (16%)
Query: 1565 SPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRG 1624
+P TT+EP P + ++ T + K P T P+ P P +P E
Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEP---- 358
Query: 1625 VSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPN------PTYPHLYPPYLIR 1678
P PT+ P A P+ AP PT P P +
Sbjct: 359 -------APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 411
Query: 1679 GYPDTAALENRQTIINDYI-TSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRG 1737
T E T + T+ + A +P+E S P
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-- 469
Query: 1738 IIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLT-KPT 1796
P P P P T + P P P +++ +P +P P T K T
Sbjct: 470 -----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK-KPAPTTPKEPAPTTPKET 523
Query: 1797 TTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIW----RPGTEQSSGSSGSSGGGG 1852
++ ++ E+ EK TT E AP P T + +
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 581
Query: 1853 GSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSS 1912
+ PA +P P + P+ T T + + PT L+ + ++
Sbjct: 582 NTPKEPA------PTTPKEPAPTTPKEPAPTTPKETAP----TTPKGTAPTTLKEPAPTT 631
Query: 1913 PVRPA--ATFPPATHCPLGGTLDGVYPTLME---PVLLPKEAPRVARPERPRADTGHA-- 1965
P +PA P T P T D PT + P + AP + P G A
Sbjct: 632 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691
Query: 1966 -------FLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDP 2018
K PA L P ++ S P + T TP + P +P
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE---PAPTTPKK 748
Query: 2019 PAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLP 2078
PAP + P S P + +E P + S+P L+ + P
Sbjct: 749 PAPTTPETPPPTTSEVSTPTTTKE--------------PTTIHKSPDESTPELSAEP-TP 793
Query: 2079 KHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPH-------------LRPLPE---SQPS 2122
K LE PK+PG AA P LR PE + P
Sbjct: 794 KALEN----------SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 843
Query: 2123 SSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLD 2182
+ T ++ ++ TQD T L AP + + +
Sbjct: 844 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 903
Query: 2183 LRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPG 2242
+ P + P D ++ + +P+P K P P+ T
Sbjct: 904 IMNKPEET-AKPKDRATNSKAT--------TPKPQK------------PTKAPKKPTST- 941
Query: 2243 HSRSAVYPLLYRDGEQTEPSRMGSKSP--GNTSQPPAFFSKLTESNSAMVKSKKQEINKK 2300
+ P + + P +M S P TS+ + T + SK E+N K
Sbjct: 942 -KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPK 1000
Score = 51.6 bits (122), Expect = 1e-05
Identities = 80/352 (22%), Positives = 125/352 (35%), Gaps = 56/352 (15%)
Query: 735 ECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPP-TPPPEDIPAP 793
E + T +S T P+P T K+T PK PA P P P TPPP
Sbjct: 708 ELAPTTTKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 794 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAV 853
T T T +P + P SA P E +E K PAA + +
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV-------PTTKTPAATKPEM 818
Query: 854 DTGKAEEPVKSECTEEAEEGPAKGK----DAEAAEATAEGALKAEKKEGGSG-------- 901
T ++ + + E A K A E T E + A + S
Sbjct: 819 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF 878
Query: 902 RATTAKSSG-APQDSDSSATCSADEV-----DEAEGGDK---NRLLSPRPSLLTPTGDPR 952
+ TT K++ AP+ + + T + E+ + A+ D+ ++ +P+P PT P+
Sbjct: 879 KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ--KPTKAPK 936
Query: 953 ANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQ 1012
S +KP + ++++ K PR+ T P P + +
Sbjct: 937 KPTSTKKPKTMPRVRK---------PKTTPTPRK---MTSTMPELNPTSRIAEAMLQTTT 984
Query: 1013 QPGSSPRGKSRSPAPPAD----KEAEKP-------VFFPAFAAEAQKLPGDP 1053
+P +P K P ++ E E P VF P + LP P
Sbjct: 985 RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVP 1036
>gi|7661892 REST corepressor 1 [Homo sapiens]
Length = 482
Score = 105 bits (262), Expect = 6e-22
Identities = 74/285 (25%), Positives = 134/285 (47%), Gaps = 19/285 (6%)
Query: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
W+ ++K F + F H K F I L K++A V +YY KK S++ R R++
Sbjct: 192 WTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQ- 250
Query: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDK-----EDLL 546
+++++ + + ++ P+ E KE +KE E P+V+ +K ++
Sbjct: 251 -KREREESEDELEEANGNNPI---DIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRA 306
Query: 547 KEKTDD---TSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAE 603
K K S ED + A A+ + R + N + A+ +
Sbjct: 307 KRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGG 366
Query: 604 LASMELNE-----SSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKK 658
+ L E ++RWT EE A + + ++GR++ AI+ ++G+K+V Q KNF+ NY++
Sbjct: 367 IEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRR 426
Query: 659 RQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDE 703
R N+DE+LQ+ + + KE +K P + + + P EDE
Sbjct: 427 RFNIDEVLQEWEAEHGKEETNGPSNQK-PVKSPDNSIKMPEEEDE 470
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 101 bits (251), Expect = 1e-20
Identities = 285/1276 (22%), Positives = 414/1276 (32%), Gaps = 214/1276 (16%)
Query: 739 PATVNNSSDTESIPSPHTEAAKDTG-QNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPT 797
P T +S + SP E +N P TL P P P P+
Sbjct: 660 PTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTT------LPLVPTASENCPVAPS 713
Query: 798 PASEATG------APTPPPAPPSPSAPPPVVPKEEKE----EETAAAPPVEEGEEQKP-- 845
P + AP P + PSPS PP P K+ T+A PV ++ P
Sbjct: 714 PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE 773
Query: 846 -PAAEELAVDTG------KAEEPVKSECTEEAEEGPAK----GKDAEAAEATA-----EG 889
A A G + P+ + + + P K G D ++ E
Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833
Query: 890 ALKAEKKEG--GSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLT- 946
+ E GS + S P + T SA +G +P PS++
Sbjct: 834 SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL 893
Query: 947 --PTGDPRANASPQKP-LDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPA--PPAPPPP 1001
P P A Q P L + + A P + P APT PA PP+P
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953
Query: 1002 QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAF---------AAEAQKLPGD 1052
AP P ++P PA P+ K A P PA A + K
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP---PAATPPSPKGGPATPSPKGAPT 1010
Query: 1053 PPCWTSGLPFPVP---PREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTI 1109
PP T P P P ++P A P + +P PLP G T LP P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 1110 SNPPPLISSAKHPSVL-ERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKL 1168
P L + P+ G + +P + +P G GL P P K
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG----GLATP--PHKG 1124
Query: 1169 APFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSIT---KGIPSTRVP 1225
AP + SP+G P G PT A+ S GG T KG P+T P
Sbjct: 1125 APTTPAATPP-SPKGGLATPPPKGAPTTPAATP------PSPKGGLATPPPKGAPTT--P 1175
Query: 1226 SDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEGKKGHVL 1285
+ + + +G + +P KG T PS PKG + KG
Sbjct: 1176 AATPPSPKGGLATPSP-----KGAPT-TPAATPPS----------PKGGLATPSPKGAPT 1219
Query: 1286 SYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAISSASIEGLMGRAIPPE 1345
+ + T S + G ++ P P T +G G A PP
Sbjct: 1220 T----PAATPPSPKGGLATPSPKGAPTTPAATPPSPKG---------------GPATPPP 1260
Query: 1346 RHSP-HHLKEQHHIRGSIT----QGIPRSYVEAQEDYLRREAKLLKREGTPPPPPPSRDL 1400
+ +P ++G + +G P V PP P
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAV------------------VTPPSPKGGPA 1302
Query: 1401 TEAYKTQALGPLKLKPAHEGLVATVKEAGR-SIHEIPREELRHTPELPLAPRPLKEGSIT 1459
T K P P+ +G T G + + + TP LP A P +G T
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP-ATTPSSKGGPT 1361
Query: 1460 QGTPLKYDTGASTTGSKKHDVRSLIGSPGR-----------TFPPVHPLD-VMADARALE 1507
+ + T + T S K SP R T P V PL A A +
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT 1421
Query: 1508 R--------------ACYEESLKSRPGTASSSGGSI---ARGAPVI-------------- 1536
R A SLK P T++ GG ++G P +
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Query: 1537 --VPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTTRE----PTPRLQEGSLSSSKASQDR 1590
V P+++P T GAP LP P + +E P+ R + +++ S+
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAP---TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538
Query: 1591 KLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSI-----P 1645
T P+E P TVP P P + + P A P++ P
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPK--EAPATPSSKEASSPPAVTPSTYKGAPSP 1596
Query: 1646 RGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHN 1705
+ + + A P+ PT P + PP +G P T A + T + +T + +
Sbjct: 1597 KELLIPPAVTSPSPKEA---PTPPAVTPPSPEKG-PATPAPKGTPT--SPPVTPSSLKDS 1650
Query: 1706 AATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVP---HLPVLVPPTPGTPATAM 1762
+ + M G + ++S L GP + ++ P P++ PT P T
Sbjct: 1651 PTSPASVTCKM--GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKK 1708
Query: 1763 DRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSIL 1822
P P P + S PLS P L P SS+ + +D K L
Sbjct: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLL-PVQKDSSKTAKGKDASHS-----PKGPL 1762
Query: 1823 TSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRP 1882
+ P+ E+ S + S P S A P P Q L P
Sbjct: 1763 APPESKASTPLTAAAFEKVL-PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP 1821
Query: 1883 SVLHNTGMKGIITAVE 1898
++ + K + A E
Sbjct: 1822 GLVLESPSKPLAPADE 1837
Score = 95.1 bits (235), Expect = 8e-19
Identities = 131/520 (25%), Positives = 173/520 (33%), Gaps = 55/520 (10%)
Query: 732 PRGECSGPATVNNSSDTESIPSPHTEAAKDT-GQNGPKPPATLGADGPPPGPPTPPPEDI 790
P+G + PA S +P + A P P + A P G PT P +
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
Query: 791 PAPTEPTPASEATGAPTPPPA-PPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE 849
P+P GAPTPP A PPSP P + AA PP +G PP
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP--- 1121
Query: 850 ELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSS 909
P T + +G + A T + K G T
Sbjct: 1122 -------HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK-----GGLATPPPK 1169
Query: 910 GAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQR 969
GAP T A +GG SP+ + TP P + K
Sbjct: 1170 GAP-------TTPAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220
Query: 970 AAAIPPIVTKVHEPPREDAAPTKPA--PPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAP 1027
AA PP P APT PA PP+P P AP P ++P A
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280
Query: 1028 PADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPP 1087
P K A P A P P + P PP A+P +P S + P
Sbjct: 1281 PPHKGAPNP------AVVTPPSPKGGPATSPPKGAPTPP----AATPPSPKGSPGTPPPK 1330
Query: 1088 GHPLPLGL---HDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPY 1144
G P P + P LP S P S+K + G ++ P
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390
Query: 1145 SEHA-KAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLR 1203
A +P G T +P+ PKK AP + V +E G A P + P A +
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKK-APATPVTRE-----GAATPSKGDLTPPA-----VT 1439
Query: 1204 GTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPAD 1243
+L P S KG P+T PS ++T +P +
Sbjct: 1440 PVSLKKAPATSAPKGGPAT--PSSKGDPTLPAVTPPSPKE 1477
Score = 92.8 bits (229), Expect = 4e-18
Identities = 238/996 (23%), Positives = 316/996 (31%), Gaps = 156/996 (15%)
Query: 724 LHASGNEVPRGECSGPATVNNSSDTE--SIPSPHTEAAKDTGQNGPKP------PATLGA 775
L G +P E P+ VN E + P+P A + PK P + A
Sbjct: 873 LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932
Query: 776 DGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPA-PPSPSAPPPVVPKEEKEEETAAA 834
P G PTPP P+P APTPP A PPSP P + AA
Sbjct: 933 SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992
Query: 835 PPVEEG--------EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEAT 886
PP +G PPA + A P + P K + AA
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 887 AEGA--LKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL 944
+GA A G T GAP + +AT + + A K +P P
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAP--TPPAATPPSPKGGPATPSPKG---APMPPA 1107
Query: 945 LTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPA--PPAPPPPQ 1002
TP A+P K AA PP P APT PA PP+P
Sbjct: 1108 ATPPSPKGGLATPPH----KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 1003 NLQPESDAPQQPGS---SPRGKSRSPAP---PADKEAEKPVFFPAFAAEAQK-----LPG 1051
P AP P + SP+G +P+P P A P A + K
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 1052 DPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPP--GHPLPL---------GLHDTAR 1100
PP GL P P + P P PP G P P GL
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 1101 PVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLP 1160
P P ++ P P A P GA + + S P G T
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPK-----GAPTPPAATPPSPKGSPGTPPPKGAPTPPAV 1338
Query: 1161 LPMDPKKL----APFSGVKQEQLSPRGQAGP------PESLGVPTAQEASVLRGTALGSV 1210
P PK A K +P + GP P G P S RG A+ S
Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398
Query: 1211 PGGSITKGI--PSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGRED 1268
G + + S + + +T G+ T KG +T +P L +
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPS-------KGDLTP--PAVTPVSLKKAPAT 1449
Query: 1269 SLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRA 1328
S PKG KG +VT S P E APK+ + A
Sbjct: 1450 SAPKGGPATPSSKGDPTL----PAVTPPS----------PKEPPAPKQVATSSSPKKAPA 1495
Query: 1329 ISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRRE--AKLLK 1386
+ + IP SP + T R + L ++ A L
Sbjct: 1496 TPAPMGAPTLPAVIP---SSPKEV--------PATPSSRRDPIAPTATLLSKKTPATLAP 1544
Query: 1387 REGTPPP--PPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREELRHTP 1444
+E PP PS T A T P V + P+E L P
Sbjct: 1545 KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL--IP 1602
Query: 1445 ELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADAR 1504
+P P + + TP + G +T K G+P T PPV P
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK--------GTP--TSPPVTP-------- 1644
Query: 1505 ALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKP-RQSPLTYEDHGAPFAGHLPR 1563
SLK P S + + GA V G P ++ P ++ P
Sbjct: 1645 --------SSLKDSP--TSPASVTCKMGATVPQASKGLPAKKGPTALKE---VLVAPAPE 1691
Query: 1564 GSPVTTREPT---PRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE- 1619
+P+ T PT P+ ++ S +S D + + +K P STV P P+ P +
Sbjct: 1692 STPIIT-APTRKGPQTKKSSATSPPICPD----PSAKNGSKGPLSTVA---PAPLLPVQK 1743
Query: 1620 HLLRGVSGVDLYRSHIPLA-FDPTSIPRGIPLDAAA 1654
+ G D SH P P PL AAA
Sbjct: 1744 DSSKTAKGKD--ASHSPKGPLAPPESKASTPLTAAA 1777
Score = 84.0 bits (206), Expect = 2e-15
Identities = 105/417 (25%), Positives = 147/417 (35%), Gaps = 67/417 (16%)
Query: 684 KKAPAAASEEAA--FPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEV---PRGECSG 738
KKAPA + A P V+ E + + + L + P+
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
Query: 739 PA-TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATL-----GADGP-----PPGPPTPPP 787
PA TV + T +IP+P A + + PPA GA P PP +P P
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP 1610
Query: 788 EDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPA 847
++ P P TP S G TP AP PPV P K+ T+ A + P A
Sbjct: 1611 KEAPTPPAVTPPSPEKGPATP--APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668
Query: 848 AEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAK 907
++ L A++GP K+ A A + TA
Sbjct: 1669 SKGLP-----------------AKKGPTALKEVLVAPAPESTPI------------ITAP 1699
Query: 908 SSGAPQDSDSSATCSADEVD-EAEGGDKNRLLSPRPSLLTPTGDPR--------ANASPQ 958
+ PQ SSAT D A+ G K L + P+ L P A+ SP+
Sbjct: 1700 TRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPK 1759
Query: 959 KPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPP-----APPPPQNLQPESD-APQ 1012
PL + K KV P + P+PP AP P L P+ P
Sbjct: 1760 GPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPS 1819
Query: 1013 QPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEA----QKLPGDPPCWTSGLPFPVP 1065
PG S+ P PAD++ P+ P + L P ++G+P P P
Sbjct: 1820 SPGLVLESPSK-PLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTP 1875
Score = 65.9 bits (159), Expect = 5e-10
Identities = 377/1696 (22%), Positives = 534/1696 (31%), Gaps = 338/1696 (19%)
Query: 733 RGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKP-PATLGADGPPPGPPTPPPEDIP 791
+G S PA ++ S T+S+P T + K G N P P +LG+ P + +
Sbjct: 267 KGPVSPPAALSLS--TQSLPVV-TSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLL 323
Query: 792 APTEPTPASEAT-------GAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQK 844
T P+ S+ T + T P S PP+ + E T AA PV K
Sbjct: 324 GQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDK 383
Query: 845 PPA---------AEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEK 895
P+ + L V T + P S + + AT L A+
Sbjct: 384 GPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN------------ATYHYPLVAQM 431
Query: 896 KEGGSGRATTAKSS-----GAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGD 950
G ++ AP + ATC +SP S
Sbjct: 432 PVSSVGTTPLVVTNPCTIAAAPTTTFEVATC----------------VSPPMS-----SG 470
Query: 951 PRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTK-PAPPAPPPPQNLQ---- 1005
P +N P P A + P+ K EP + A + P P P P++L+
Sbjct: 471 PISNIEPTSPA--------ALVMAPVAPK--EPSTQVATTLRIPVSPPLPDPEDLKNLPS 520
Query: 1006 ------PESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTS- 1058
P Q +S G SPA + P P A + P +S
Sbjct: 521 SVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSP 580
Query: 1059 ---------------GLPFPVPPREVIKASPHAPDPSAF-----SYAPPGHPLPLGLHDT 1098
G P P+ SP + SA SYA P PL
Sbjct: 581 EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSL 640
Query: 1099 ARPVLPRPPTISNPPPLIS--SAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVT 1156
P + P S P ++ +AK S +G +V L P + K G +T
Sbjct: 641 ITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG-TVSL-APKNHPVKE--GTLT 696
Query: 1157 MGLPLPMDPKKLAPFSGVKQEQLSPRGQA--GP--PESLGVPTAQEASVLRGTALGSVPG 1212
LPL + P + Q +P P P+S+ P+ A G+ PG
Sbjct: 697 T-LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPA--------GTPPG 747
Query: 1213 GSITKGIPSTRVPSDSAITYRGSITH--GTPADVLYKGTITRIIGEDSPSRLDRGREDSL 1270
GI T + A + + T G A KGT+T + DSPS L
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLA--DSPSPL-------- 797
Query: 1271 PKGHVIYEGKKGHVLSYEGGMSVTQCSKEDG--RSSSGPPHETAAPKRTYDMMEGRVGRA 1328
G+SV+ +K + S+GP +E
Sbjct: 798 -------------------GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASF-LP 837
Query: 1329 ISSASIEGLMGRAIPPERHSPHHLKEQHHIRGS-ITQGIPRSYVEAQEDYLRREAKLLK- 1386
+S S +G + P HSP + S +T P+ ++ L
Sbjct: 838 ENSLSFQG--SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895
Query: 1387 -REGTPPPPP---PSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREELRH 1442
+EG P P P+ +T + +A + PA +G+ A+ G
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKA----RATPAPKGIPASPSPKGAP----------- 940
Query: 1443 TPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMAD 1502
TP P P K G T A+T S K G P P P A
Sbjct: 941 TPPAATPPSP-KGGPATPSPKWAPTPPAATPPSPK-------GGPATPSPKGAPTPPAAT 992
Query: 1503 ARALERACYEESLKSRPGTASSSGGSIARGAPVIVPEL--GKPRQSPLTY---------- 1550
S K P T S G A P + P G P +P
Sbjct: 993 P---------PSPKGGPATPSPKG---APTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 1551 -EDHGAPFAGHLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPE 1609
G+P A LP+G+P T P + G + S +TP P + P+
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
Query: 1610 HHPHPISPYEHLLRGVSGVDLYRS--HIPLAFDP-------TSIPRGIPLDAAAAYYLPR 1660
P P + +G ++ P A P T P+G P AA P+
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160
Query: 1661 -HLAP-----NPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNAATAMAQRA 1714
LA PT P PP G A + T AT + A
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGG---LATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1217
Query: 1715 DMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTP-GTPATAMDRLAYLPTAPQ 1773
+P L P+G P P PP+P G PAT + A P A
Sbjct: 1218 PTTPAATPPSPKGGL-ATPSPKG------APTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 1774 PFSSR-------HSS-------SPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREK 1819
P S + H +P SP G + P + + K
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 1820 SILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSR------PA---SHSHAHQHSPI 1870
T +P GT ++ SS GG + S PA SH +P
Sbjct: 1331 GAPTPPAVTPPSP---KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387
Query: 1871 SPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSS--PVRPAATFP------P 1922
SP+ A+ + + + P+TP +T S + P A P P
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447
Query: 1923 ATHCPLGGTL------DGVYPTLMEPVLLPKEAP---RVARPERPRADTGHAFLAKPPAR 1973
AT P GG D P + P PKE P +VA P+ P
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPP--SPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Query: 1974 SGLEPASSPSKGSEPRPLVPPVSGHATI--ARTPAKNLAPHHA-------------SPDP 2018
+ P+S + P P++ AT+ +TPA LAP A +P
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA-TLAPKEALIPPAMTVPSPKKTPAI 1564
Query: 2019 PAPPASASDPHREKTQSKPF----------SIQELELRSLGYHGS---SYSPEGVEPVSP 2065
P P + + P ++ S P S +EL + S + +P V P SP
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 2066 VSSPSLTHDKGLPKHLEELDKSHLEGELRP--------------KQPGPVKLGGEAAHLP 2111
P+ KG P S + P + P K G A
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684
Query: 2112 HLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQ--LSAPLPAP 2169
+ P PES P + TAP KG Q + A S I D + + + LS PAP
Sbjct: 1685 LVAPAPESTP-----IITAPTRKGPQTKKSSA--TSPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 2170 LYSFPGASCPVL---DLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGE 2226
L S D P PP + + E K P+P SV
Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE--KVLPKPESASVSAAPS 1795
Query: 2227 DGIE-PVSPPEGMTEP 2241
+ P++P T P
Sbjct: 1796 PPVSLPLAPSPVPTLP 1811
Score = 54.3 bits (129), Expect = 1e-06
Identities = 133/567 (23%), Positives = 179/567 (31%), Gaps = 120/567 (21%)
Query: 1733 AGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSS--PLSPGGPT 1790
+ P ++ S +P + + +PAT + PT P P + S+ PLSP G T
Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATT-----HSPTPPSPKGAPTPSAVTPLSPKGVT 879
Query: 1791 HLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGG 1850
K T T S V + P + G + +
Sbjct: 880 LPPKETPTPS---------------------------VVNLPFPKEGPATPAPKQAPALS 912
Query: 1851 GGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTST 1910
SS + A + A + P SP + A P KG P+TP+
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGA--PTPPAATPPSPKG-----GPATPS-----PK 960
Query: 1911 SSPVRPAATFP-----PATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHA 1965
+P PAAT P PAT P G P P PK P A P A T A
Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPTP---PAATPPS--PKGGP--ATPSPKGAPTPPA 1013
Query: 1966 FLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASA 2025
PP+ G A+ KG+ P P S + A TP AP + P+P
Sbjct: 1014 --VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071
Query: 2026 SDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELD 2085
+ P + + +P P SP P+ KG P
Sbjct: 1072 ATPSLK---------------------GAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110
Query: 2086 KSHLEGELRPKQPG---------PVKLGGEAAHLPHLRP-LPESQPSSSPLLQTAPGVKG 2135
S G P G P GG A P P P + P S P KG
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Query: 2136 HQRVVTLAQHISEVITQDYTRHHPQ-QLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPP 2194
T T P+ L+ P P + P A+ P P L P
Sbjct: 1171 ------------APTTPAATPPSPKGGLATPSPKGAPTTPAATPP-----SPKGGLATPS 1213
Query: 2195 PDHG--APARGSPHSEGGKRSPE----PNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAV 2248
P PA P +GG +P P + G PP+G P A
Sbjct: 1214 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTP----PAA 1269
Query: 2249 YPLLYRDGEQTEPSRMGSKSPGNTSQP 2275
P + G T P + G+ +P + P
Sbjct: 1270 TPPSLKGGLATPPHK-GAPNPAVVTPP 1295
Score = 43.5 bits (101), Expect = 0.003
Identities = 129/595 (21%), Positives = 188/595 (31%), Gaps = 98/595 (16%)
Query: 1732 AAGPRGIIDLSQVPHLPVLVPPTPGTPATAMD---RLAYLPTAPQPFSSRHSSSPLSPGG 1788
++GP I+ + P V+ P P P+T + R+ P P P ++ S +
Sbjct: 468 SSGPISNIEPTS-PAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKF 526
Query: 1789 PTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSS 1848
PT T +S E + +++ ++L V+ AP P + +S S
Sbjct: 527 PTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVL---PLVQAAPKNSPSFQSTSSSPEIP 583
Query: 1849 GGGGGSSSRPASHSHAHQHSPISPRTQD-ALQQRPSVLHNTGMKGIITAVEPSTPTVLRS 1907
+ ++ + P S T + SV+ G P + L
Sbjct: 584 LSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAG------PDSAGPLLK 637
Query: 1908 TSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFL 1967
+S +P A FP + P G AP A+ T FL
Sbjct: 638 SSLITPT--VAAFPLESADPAG------------------VAPTTAKGTSTYTTTASPFL 677
Query: 1968 AKPPARSGLEPASSPSKGS--EPRPLVPPVSGHATIARTPAKNLAP----------HHAS 2015
L P + P K PLVP S + +A +P AP +
Sbjct: 678 ---EGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSV 734
Query: 2016 PDPPAPPAS--------------------ASDPHREKTQSKPFSIQELELRSLGYHGSSY 2055
P P PPA AS P T+ S +L Y S
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 2056 SPEGVEPVSPVSS--PSLTHDKGLPKHLEELDK--SHLEGELRPKQPGPVKLGGEAAHLP 2111
SP GV VSP + P+ G + L S +E P+ + ++
Sbjct: 795 SPLGVS-VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853
Query: 2112 HLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQH---ISEVITQDYTRHHPQQLSAPLPA 2168
H P + + +P T KG VTL V+ + + P AP A
Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKG----VTLPPKETPTPSVVNLPFPKEGP-ATPAPKQA 908
Query: 2169 PLYSFPGASCPVLDLRRPPSDLYLPPPDHGA---PARGSPHSEGGKRSPEPNKTSVLGGG 2225
P S +S P + P GA PA P +GG +P P
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT---- 964
Query: 2226 EDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMG---SKSPGNTSQPPA 2277
P SP G P + P T PS G + SP PPA
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPP------AATPPSPKGGPATPSPKGAPTPPA 1013
Score = 39.3 bits (90), Expect = 0.050
Identities = 51/217 (23%), Positives = 79/217 (36%), Gaps = 43/217 (19%)
Query: 736 CSGPATVNNSSDTESI--PSPHTEAAKDTGQNGPKPPATLGADGPPPGPPT--------- 784
C P+ N S S P+P KD+ + A+ GP P +
Sbjct: 1717 CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAA 1776
Query: 785 ------PPPEDIPAPTEPTPASEATGAPTPPPAPPS-----PSAP--------PPVVPKE 825
P PE P+P AP+P P P PS+P P+ P +
Sbjct: 1777 AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPAD 1836
Query: 826 EKE-------EETAAAPPVEEGEEQKP-PAAEELAVDTGKAEEPV----KSECTE-EAEE 872
E E E + P + P P + + V T A++PV K TE +++E
Sbjct: 1837 EDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDE 1896
Query: 873 GPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSS 909
+ ++ ++ +AT + A A E + AK S
Sbjct: 1897 SVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQS 1933
Score = 37.7 bits (86), Expect = 0.14
Identities = 57/215 (26%), Positives = 75/215 (34%), Gaps = 32/215 (14%)
Query: 1018 PRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGD---PPCWTSGLPFPVPPREVIKASP 1074
P + P P A+ A P+ A PG PPC S P P +ASP
Sbjct: 10 PATEQELPQPQAET-AVLPMSSALSVTAALGQPGPTLPPPC--SPAPQQCPLSAANQASP 66
Query: 1075 HAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQ 1134
P PS + P P P TA P+ P + P LI P+ L A++
Sbjct: 67 F-PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAAL-----ALAS 120
Query: 1135 GMSVQLHVPYSEHAKAPVGPVTMGLP---LPMDPKKLAPFSGVKQEQLSPRGQAGPPESL 1191
M + P G P P+ LAP S K P PP S+
Sbjct: 121 PM---------------IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP-SV 164
Query: 1192 GVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPS 1226
V + L S P ++ K +PS VP+
Sbjct: 165 AVAESGSVITLSAPIAPSEPKTNLNK-VPSEVVPN 198
Score = 36.6 bits (83), Expect = 0.32
Identities = 77/321 (23%), Positives = 114/321 (35%), Gaps = 25/321 (7%)
Query: 738 GPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPT 797
G AT + + +P P E A + A LG GP T PP PAP +
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGP-----TLPPPCSPAP-QQC 56
Query: 798 PASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGK 857
P S A A +P P+P + ++ P VP + TA P+ E +
Sbjct: 57 PLSAANQA-SPFPSPSTIASTPLEVPFPQSSSGTAL--PLGTAPEAPTFLPNLIGPPISP 113
Query: 858 AEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDS 917
A + S +G A A A ++ +K T+ S A +S S
Sbjct: 114 AALALASPMIAPTLKGTPSSSAPLALVALAPHSV--QKSSAFPPNLLTSPPSVAVAESGS 171
Query: 918 SATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAA-IPPI 976
T SA + N++ PS + P +P+ SP P + + + I
Sbjct: 172 VITLSAPIAPSEPKTNLNKV----PSEVVP--NPKGTPSP--PCIVSTVPYHCVTPMASI 223
Query: 977 VTKVHEPPREDAAPTKPAPPAPPPPQNLQPES--DAPQQPGS-SPRGKSRSPAPPADKEA 1033
+ V P+ PT A P ++ S +PQ PGS S +G PA +
Sbjct: 224 QSGVASLPQ--TTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQ 281
Query: 1034 EKPVFFPAFAAEAQKLPGDPP 1054
PV + P D P
Sbjct: 282 SLPVVTSSQKTAGPNTPPDFP 302
Score = 36.2 bits (82), Expect = 0.42
Identities = 50/252 (19%), Positives = 84/252 (33%), Gaps = 44/252 (17%)
Query: 685 KAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNN 744
K P + A PV +D A G +A H+ + E +
Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKG-----------KDASHSPKGPLAPPESKASTPLTA 1775
Query: 745 SSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPED---------IPAPTE 795
++ + +P P + + P PP +L P P P PP + + +P++
Sbjct: 1776 AAFEKVLPKPESASVSAA----PSPPVSLPL-APSPVPTLPPKQQFLPSSPGLVLESPSK 1830
Query: 796 P-TPASEATGAPTPPPAP--------------PSP---SAPPPVVPKEEKEEETAAAPPV 837
P PA E P PP P P+P P P ++ +
Sbjct: 1831 PLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGT 1890
Query: 838 EEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKE 897
E ++ P EE ++ + E EE +K K + + + + K ++
Sbjct: 1891 ESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQ 1950
Query: 898 -GGSGRATTAKS 908
G R T KS
Sbjct: 1951 VTGVTRVTIRKS 1962
>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
Length = 449
Score = 100 bits (250), Expect = 1e-20
Identities = 86/311 (27%), Positives = 136/311 (43%), Gaps = 41/311 (13%)
Query: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
W+ ++K F + F H K+F I L KT+A V YYY KK + SL+ R R
Sbjct: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 203
Query: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDL------ 545
K + Q ++ PM + + +KE +KE E+ V+ K L
Sbjct: 204 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQP---VQTSKIGLGRREYQ 260
Query: 546 --------LKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANS 592
+ K G +++ VA S AN+ R+ + R + N
Sbjct: 261 SLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQV 320
Query: 593 EEAITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVS 647
A+ + + + ES+ RWT EE A +G+ ++G+++ AIA ++G+KTV
Sbjct: 321 NSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVG 380
Query: 648 QCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEA 707
Q KNF+ NY++R NL+E+LQ+ E E+ + A E + V
Sbjct: 381 QVKNFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------P 429
Query: 708 SGVSGNEEEMV 718
SG S +EEE V
Sbjct: 430 SGKSTDEEEEV 440
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 99.8 bits (247), Expect = 3e-20
Identities = 167/779 (21%), Positives = 285/779 (36%), Gaps = 106/779 (13%)
Query: 293 QWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQS 352
Q E+ F R D+L EA KV N R+ + ++ EY +R+LQ R
Sbjct: 288 QSEEWFRVRLDRLSEA--AKV----NTDAMRSAQEEITEY----------RRQLQARTTE 331
Query: 353 RVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINM 412
+ + S+ RSE E D S QE +++ DA+ + K+
Sbjct: 332 LEALKSTKDSLERQRSELEDRHQADIASYQEAIQQ------------LDAELRNTKWE-- 377
Query: 413 NGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQH-------PKNFGLIASFLERKTVAE 465
MA ++ Y+D + M + E +R+ P F L + +V+
Sbjct: 378 ---MAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVST 434
Query: 466 CVLY-----YYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEK 520
+ + +K+E +V +++ ++++++ ++++ + +EE
Sbjct: 435 HIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEA 494
Query: 521 DEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKG 580
+ E+E ++ EE E + + +KE+ + + EKE S + + +
Sbjct: 495 EGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPA 554
Query: 581 RITRSMANEANSEEAITPQQSAELASMELNESSRWTE-------EEMETAKKGLLEHGRN 633
+ EA S E + AE+ S E +S E + E AK + E ++
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 634 WSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKM-EKERNARRKKKKAPA---A 689
+ V + S + K +E K K EKE +K K+P A
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 690 ASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTE 749
S E A PV + + S +EE +A E E + + E
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734
Query: 750 SIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP 809
SP E AK + + P D P TP E+ +P + P E +P
Sbjct: 735 KAKSPVKEEAK-SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP--EKAKSPVKE 791
Query: 810 PAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEE 869
A P+ KE+ A + + EE K P EE K +EP K E
Sbjct: 792 EVKSPEKAKSPL-----KEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK---AE 843
Query: 870 AEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEA 929
E+ PA K E ++ E +A KKE + K + +S E +
Sbjct: 844 EEKAPATPKTEEKKDSKKE---EAPKKEAPKPKVEEKKEPAVEKPKESKV-----EAKKE 895
Query: 930 EGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDA- 988
E DK ++ PT + A A + D K P T+V + +DA
Sbjct: 896 EAEDKKKV---------PTPEKEAPAKVEVKEDAK---------PKEKTEVAKKEPDDAK 937
Query: 989 --APTKPAPPAPPPPQNLQPESDAPQQPGSSPRGK----------SRSPAPPADKEAEK 1035
P+KPA P+ + + ++P P+ + S+ P+ P ++AEK
Sbjct: 938 AKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996
Score = 87.8 bits (216), Expect = 1e-16
Identities = 109/425 (25%), Positives = 166/425 (39%), Gaps = 51/425 (12%)
Query: 670 KLKMEKERNARRKKKKAPAAASEEA----AFPPVVEDEEMEASGVSGNEEEMVEEAEALH 725
K+K E++ K +K E+ V E+EE EA G EEE EE EA
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEA-- 494
Query: 726 ASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGP-----PP 780
G E E P +S + SP E AK + K P A P P
Sbjct: 495 EGGEE----ETKSPPAEEAASPEKEAKSPVKEEAKSPAE--AKSPEKEEAKSPAEVKSPE 548
Query: 781 GPPTPPPEDIPAPTEP-TPASEATGAPTPPPAPP---SPSAPPPVVPKEEKEEETAAAPP 836
+P E+ +P E +P E +P +P SP+ P E K E A +P
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608
Query: 837 VEEGE---EQKPPAAEELAVDTGKAEEPVKSEC-TEEAEEGPAKGKDAEAAEAT----AE 888
EE + E K P EE A + + P K++ T+E + P K K E EA A+
Sbjct: 609 KEEAKSPAEAKSPVKEE-AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Query: 889 GALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSP-------R 941
+KAE K ++ + +P+ + S A ++A+ K SP +
Sbjct: 668 SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 942 PSLLTP----------TGDPRANASPQ--KPLDLKQLKQRAAAIPPIVTKVHEPPREDAA 989
TP P SP+ K LD+K + + A + + P + +
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 990 PTKPAPPAPPPPQN-LQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQK 1048
P K +P ++ L+ ++ AP++ + + +SP +K E V P AE +K
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKE-IPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK 846
Query: 1049 LPGDP 1053
P P
Sbjct: 847 APATP 851
Score = 64.7 bits (156), Expect = 1e-09
Identities = 107/575 (18%), Positives = 220/575 (38%), Gaps = 59/575 (10%)
Query: 79 SQELHLRPESHSYLPELGKSEME--FIESKRPRLELLPDPLLRPSPLLATGQPAGSEDLT 136
S H++ +S + + KSE E +E + ++ + + E
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE 490
Query: 137 KDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKK 196
++ + G+ E SPP+ PE E P + + ++E ++ +K
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKA 550
Query: 197 QQQLEEEAAKPPE---PEKPVSPPPIESKHRSLVQIIYDENRKKAEAAHRILEGLGP--- 250
+ +EEA PPE PEK + P E K + E K A + P
Sbjct: 551 KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610
Query: 251 ------QVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQRYDQ 304
+ + P+ + + K +++ K ++ ++ E K ++
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE--EAKSPEKAKS 668
Query: 305 LMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMS 364
++A K E+ ++ + AK EK ++++ + E+ +S V +
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSP------EKAKSPVKEEAKSPEKAKSPVKE-------E 715
Query: 365 AARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYK 424
A E S + + E + +++ A P ++ K +++ A +
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKA--KSPEKAKTLDVKSPEAKTPAKEE 773
Query: 425 DRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVR 484
R + + E+ K +E+ K S L+ A +K K V+
Sbjct: 774 ARSPADKFPEKAKSPVKEEVKSPEK----AKSPLKEDAKA--------PEKEIPKKEEVK 821
Query: 485 RSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKE- 543
+ K Q+ + ++ ++ ++++ P ++E+KD K KE+ +KE KP+VE KE
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK-KEEAPKKEAPKPKVEEKKEP 880
Query: 544 ----------DLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSE 593
+ KE+ +D EKEA A K +++ + K + + ++A ++
Sbjct: 881 AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA-KVEVKEDAKPKEKTEVAKKEPDDAKAK 939
Query: 594 EAITPQQSAELASMELN---ESSRWTEEEMETAKK 625
E P + E A + + E ++ EE+ +T K
Sbjct: 940 EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK 974
Score = 51.2 bits (121), Expect = 1e-05
Identities = 83/416 (19%), Positives = 145/416 (34%), Gaps = 53/416 (12%)
Query: 473 TKKNENYKSLVRRSYRRRGKSQQQQQ---QQQQQQQQQQQQPMPRSSQEEKDEKEKEKEA 529
TK+ + + KS ++ + + + + ++ + P+ ++ + K KE
Sbjct: 642 TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE 701
Query: 530 EKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANE 589
K EK + +E EK E+ E S ++ A S + K ++ +
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP-EKAKTLD 760
Query: 590 ANSEEAITP--QQSAELASMELNESSRWTEEEM---ETAKKGLLEHGRNWSAIARMVGSK 644
S EA TP +++ A ++ +EE+ E AK L E + K
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK--------APEK 812
Query: 645 TVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNA-------RRKKKKAPAAASEEAAFP 697
+ + + K+ + E+ + K +E A +K K A +EA P
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 698 PVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTE 757
V EE + V +E VE + +VP E PA V D + P TE
Sbjct: 873 KV---EEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK--PKEKTE 927
Query: 758 AAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA 817
AK P+D A PA + AP +
Sbjct: 928 VAKKE------------------------PDDAKAKEPSKPAEKKEAAPEKKDTKEEKAK 963
Query: 818 PPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEG 873
P PK E + + +E + K AE+ + K +P + ++A +G
Sbjct: 964 KPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKG 1019
Score = 44.7 bits (104), Expect = 0.001
Identities = 129/565 (22%), Positives = 200/565 (35%), Gaps = 97/565 (17%)
Query: 1772 PQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHA 1831
P PFS P P TH+ + E+ + + E++ +T T E
Sbjct: 417 PIPFSLPEGL-PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEE 475
Query: 1832 PIWRP--GTEQSSGSSGSSGGGGGSS-SRPASHSHAHQHSPISPRTQDALQQRPSVLHNT 1888
+ G E+ G + GG + S PA + + + SP ++A + P+ +
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA--KSPAEAKSP 533
Query: 1889 GMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKE 1948
+ + E +P SP + A PP P E P E
Sbjct: 534 EKEEAKSPAEVKSPE-----KAKSPAKEEAKSPPEAKSPE-----------KEEAKSPAE 577
Query: 1949 APRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKN 2008
V PE+ AK PA+ E A SP++ P PV A++PA+
Sbjct: 578 ---VKSPEK----------AKSPAK---EEAKSPAEAKSPEKAKSPVKEE---AKSPAEA 618
Query: 2009 LAPHHASPDPPA---PPASASDPHREKTQS--KPFSIQELELRSLGYHGSSYSPEGVEP- 2062
+P PA P A P +E+ +S K S ++ E +S S E P
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678
Query: 2063 --VSPVSSPSLTHDKGLPKHLEELD-----KSHLEGELR--PKQPGPVKLGGEAAHLPHL 2113
SPV + + + +K EE KS ++ E + K PVK E A P
Sbjct: 679 KAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK---EEAKTPEK 735
Query: 2114 RPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSF 2173
P + + SP +P ++ TL E T P + A PA F
Sbjct: 736 AKSPVKEEAKSPEKAKSP-----EKAKTLDVKSPEAKT-------PAKEEARSPAD--KF 781
Query: 2174 P-GASCPVLDLRRPPSDLYLP-PPDHGAPARGSPHSE----GGKRSPEPNKTSVLGGGED 2227
P A PV + + P P D AP + P E K +P + V +
Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK 841
Query: 2228 GIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTE-PSRMGSKSPGNTSQPPAFFSKLTESN 2286
E +P TE +D ++ E P + K + PA + +
Sbjct: 842 AEEEKAPATPKTEE-----------KKDSKKEEAPKKEAPKPKVEEKKEPA----VEKPK 886
Query: 2287 SAMVKSKKQEI--NKKLNTHNRNEP 2309
+ V++KK+E KK+ T + P
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAP 911
Score = 40.4 bits (93), Expect = 0.022
Identities = 62/265 (23%), Positives = 112/265 (42%), Gaps = 17/265 (6%)
Query: 93 PELGKSEMEFIESKRPRLELLPDPLLRPSPLLATG-QPAGSEDLTKDRSLT-GKLEPVSP 150
PE KS ++ E+K P P SP A + A + D+ + T K E SP
Sbjct: 719 PEKAKSPVKE-EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSP 777
Query: 151 ----PSPPHTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAK 206
P + + E+ P +K L ++ ++EI E+ S +K++++ E + +
Sbjct: 778 ADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837
Query: 207 PP---EPEKPVSPPPIESKHRSLVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDT 263
PP E EK + P E K S +E KK ++ E P VE P ++
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSK----KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893
Query: 264 RQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQRYDQLMEAWE--KKVERIENNPR 321
++ E+ K K+ + + A+ + + + ++ +A E K E+ E P
Sbjct: 894 KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPE 953
Query: 322 RR-AKESKVREYYEKQFPEIRKQRE 345
++ KE K ++ EK E + + +
Sbjct: 954 KKDTKEEKAKKPEEKPKTEAKAKED 978
Score = 33.9 bits (76), Expect = 2.1
Identities = 43/206 (20%), Positives = 83/206 (40%), Gaps = 14/206 (6%)
Query: 54 SPGSIIQPQRRRPSLLSEFQ-PGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLEL 112
SP + P++ + E + P +S E ++ S + E KS E +K P E
Sbjct: 574 SPAEVKSPEKAKSPAKEEAKSPAEAKSPE-----KAKSPVKEEAKSPAE---AKSPVKEE 625
Query: 113 LPDPLLRPSPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEEL 172
P SP A P E + +++ + + E P + + E P +K +
Sbjct: 626 AKSPAEVKSPEKAKS-PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV 684
Query: 173 IQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPV---SPPPIESKHRSLVQI 229
++ + V+++ +K + ++EEA P + + PV + P ++K +
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 230 IYDENRKKAEAAHRILEGLGPQVELP 255
E K E A + L+ P+ + P
Sbjct: 745 KSPEKAKSPEKA-KTLDVKSPEAKTP 769
>gi|27734799 REST corepressor 2 [Homo sapiens]
Length = 523
Score = 99.8 bits (247), Expect = 3e-20
Identities = 100/408 (24%), Positives = 167/408 (40%), Gaps = 42/408 (10%)
Query: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
W+ ++K F + F H K F I L K + V YYY KK + S++ R RR G
Sbjct: 135 WTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLG 194
Query: 492 KSQQQQQQQQQQQQQ---QQQQPMPRSSQEEK-DEKEKEKEAEKEEEKPEVENDKEDLLK 547
+ ++ + ++ + + +P P + E + +++ +V + L+
Sbjct: 195 GRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRHHPLR 254
Query: 548 EKTDDTSGEDNDEKEAVASKGR--------KTANSQGRRKGRITRSMANEANS-----EE 594
+ G + A G + +SQ R +SM +S E
Sbjct: 255 TRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEG 314
Query: 595 AITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYF 654
I P + E A+ + N SRWT +E A + + +G+++ AIA ++G+KT++Q K F+
Sbjct: 315 GIDPLRPPE-ANTKFN--SRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFV 371
Query: 655 NYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNE 714
+Y++R NL+E+LQ+ + + + A ++A A A P + ED+E++ + VS +
Sbjct: 372 SYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPA--PALEEDDEVQITSVSTSV 429
Query: 715 EEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLG 774
VP P + S + P A Q PP G
Sbjct: 430 P-------------RSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQ---PPPLQQG 473
Query: 775 ADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPP----APPSPSAP 818
P P PP + P P A P PPP AP P AP
Sbjct: 474 RFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
Score = 38.1 bits (87), Expect = 0.11
Identities = 25/95 (26%), Positives = 37/95 (38%), Gaps = 3/95 (3%)
Query: 757 EAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPP-SP 815
EA +D P P P P P +++ + T + PPP PP S
Sbjct: 387 EAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
Query: 816 SAPPPVV--PKEEKEEETAAAPPVEEGEEQKPPAA 848
S PPP++ P PP+++G +P A
Sbjct: 447 SQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLA 481
Score = 36.6 bits (83), Expect = 0.32
Identities = 37/143 (25%), Positives = 56/143 (39%), Gaps = 27/143 (18%)
Query: 954 NASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPT-----KPAPPAPPPPQNLQ--- 1005
+ +P P+ +++ ++ A P + + E + + PAPP PPPP +L
Sbjct: 391 DGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPP 450
Query: 1006 -----PESDAP---QQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWT 1057
P AP +QP +G+ P A + P+ PA AA
Sbjct: 451 PLLRPPLPTAPTLLRQPPPLQQGRFLQPR-LAPNQPPPPLIRPALAAPRH---------- 499
Query: 1058 SGLPFPVPPREVIKASPHAPDPS 1080
S P P PP +I A P PS
Sbjct: 500 SARPGPQPPPTLIGAPLEPPAPS 522
Score = 32.3 bits (72), Expect = 6.1
Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 11/51 (21%)
Query: 1066 PREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT-ISNPPPL 1115
PR V A P P P++ S PP RP LP PT + PPPL
Sbjct: 430 PRSVPPAPPPPPPPTSLSQPPP----------LLRPPLPTAPTLLRQPPPL 470
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 91.7 bits (226), Expect = 8e-18
Identities = 180/807 (22%), Positives = 279/807 (34%), Gaps = 165/807 (20%)
Query: 432 WSEQEKETFREKFMQHPKNFGLIAS-FLERKTVAECVLYYYLTKKN-ENYKSLVRRSYRR 489
W+E E + F + Q+ KNF I L K E + +YY KK E S R +RR
Sbjct: 396 WTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASSRAHRRHRR 455
Query: 490 RGKSQQQQQQQQQQQQQQQQQP-------MPRSSQEEKDEKEKEKEAE------------ 530
+ ++ + + +P + +S+++ D ++ E+E +
Sbjct: 456 QAVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTS 515
Query: 531 ----------------------KEEEKPEVENDKEDL------LKEKTDDTSGEDNDEKE 562
K E P +E + +KE+ D SG+ +
Sbjct: 516 KDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTR 575
Query: 563 AVASKGRKTANSQGRRKGRITRS-MANEANSEEAITPQQSAELASMELNESSRWTEEEME 621
S+G + GR+K + + N + + + S AS N+S + E
Sbjct: 576 R--SRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDS------KAE 627
Query: 622 TAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARR 681
T KK A+ V + S K+ KRQ + K+ + E R
Sbjct: 628 TVKKS-----------AKKVKEEASSPLKS-----NKRQ-------REKVASDTEEADRT 664
Query: 682 KKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPAT 741
KK ++E + P + E E+S ++ +++ G+ P+
Sbjct: 665 SSKKTK---TQEISRPNSPSEGEGESS-----------DSRSVNDEGSSDPKD-----ID 705
Query: 742 VNNSSDTESIPSPH-TEAAKDTGQNGP----KPPATLGADGPPPGPPTPPPEDIPAPTE- 795
+N S + SIPSP E+ D+ +PPA G P P + PP PT
Sbjct: 706 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 765
Query: 796 PTPASEAT---GAPTPPPAPPSPSAPPPVVPKEEKEEETAAAP--PVEEGEEQKPPAAEE 850
PTP++ A G+PT AP P AP VP ++ A P P P
Sbjct: 766 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP 825
Query: 851 LAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAE---------KKEGGSG 901
L TG A +P + P G+ + G L + G
Sbjct: 826 LQPLTGSAGQP----SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQG 881
Query: 902 RATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPL 961
+A S A S ++ +++ + + L P P + P PQ P
Sbjct: 882 QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 941
Query: 962 DLKQLKQRAAAIP-PIVTKVHEPPREDAAP-----TKPAPPAPPPPQNLQPESDAPQQPG 1015
+ P P + PP P T P A PPP L P+S
Sbjct: 942 PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP 1001
Query: 1016 SSPRGKSRS---PAPPAD-------KEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVP 1065
+ P G ++S P PPA + A +P F A+ +PG PP T P P
Sbjct: 1002 AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF-----AQHPFVPGGPPPIT---PPTCP 1053
Query: 1066 PREVIKASP--HAPDPSAFSYAPPGH-------PLPL------GLHDTARPVLPRPP--T 1108
A P A P + + A G PLP L D P P PP +
Sbjct: 1054 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113
Query: 1109 ISNPPPLISSAKHPSVLERQIGAISQG 1135
S P ++ + H S R + +G
Sbjct: 1114 PSPEPTVVDTPSHASQSARFYKHLDRG 1140
Score = 47.8 bits (112), Expect = 1e-04
Identities = 87/379 (22%), Positives = 132/379 (34%), Gaps = 58/379 (15%)
Query: 1802 ERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASH 1861
ERER++++E++R+RERE+ E + SS G S P
Sbjct: 1181 EREREKEKEKERERERERE-----------------REAERAAKASSSAHEGRLSDPQLS 1223
Query: 1862 SHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSP-VRPAATF 1920
H P P + +T + T E + P V+ T+ + P P
Sbjct: 1224 GPGHMRPSFEPPPTTIAAVPPYIGPDT--PALRTLSEYARPHVMSPTNRNHPFYMPLNPT 1281
Query: 1921 PP--ATHCPLGGTLDGVYPTLMEPVLLPKE-APRVARPERPRADTGHAFLAKPPARSGLE 1977
P A H P L V PT+ E L +E R R R F KPP L
Sbjct: 1282 DPLLAYHMP---GLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLH 1338
Query: 1978 PASSPSK--GSEPRPLVPPVSGHATIARTPAKNLAPH-HASPDPPAPPASASDPHREKTQ 2034
PA++P + +PP +G PH AS P P Q
Sbjct: 1339 PAANPMEHFARHSALTIPPTAG-------------PHPFASFHPGLNPLERERLALAGPQ 1385
Query: 2035 SKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELR 2094
+P L + H + +P++ + ++T P H + SH+ L
Sbjct: 1386 LRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVT-----PHHHQH---SHIHSHLH 1437
Query: 2095 PKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQ--HISEVITQ 2152
Q P+ G P + PL ++ P L P G L Q H E++
Sbjct: 1438 LHQQDPLHQGSAGPVHPLVDPL-----TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRH 1492
Query: 2153 D-YTRHHPQQLSAPLPAPL 2170
+ +P+ L +P P+
Sbjct: 1493 PVFGTPYPRDLPGAIPPPM 1511
Score = 43.5 bits (101), Expect = 0.003
Identities = 197/932 (21%), Positives = 300/932 (32%), Gaps = 229/932 (24%)
Query: 1405 KTQALGPLKL-KPAHEGLVATVKEAGRSIHEIPREELRHTPELPLAPRPLKEGSITQGTP 1463
K +A PLK K E + + +EA R+ + + + P P EG +
Sbjct: 637 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEG----EGESSDSRS 692
Query: 1464 LKYDTGASTTGSKKHDVRSLIGSPGRTFPPV-HPLDVMADARALERACYEESLKSRPGTA 1522
+ D G+S D RS T P + P D +D+ + + ++ L+++P
Sbjct: 693 VN-DEGSSDPKDIDQDNRS-------TSPSIPSPQDNESDS---DSSAQQQMLQAQPPAL 741
Query: 1523 SSSGG--SIARGAPVIVPELGKPRQSP--LTYEDHGAPFAGHLPRGSPVTTREPTPRL-- 1576
+ G AP P+L P +P G+P A P P P P
Sbjct: 742 QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN-QPQAPTAPVPHTHI 800
Query: 1577 -QEGSLSSSKASQD------------RKLTSTPREIAKSPHSTVPEH------------- 1610
Q +L + + LT + + + H+ P H
Sbjct: 801 QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 860
Query: 1611 ----HPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPR------ 1660
HP P P+ + G + A+ TS+ A + PR
Sbjct: 861 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920
Query: 1661 ------HLAPNPTYP---------HLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHN 1705
H+ P PT P H +PP+L P + ++S HH
Sbjct: 921 APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH- 979
Query: 1706 AATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRL 1765
+A ++ P SS A P G L+Q +LP PP P T + ++
Sbjct: 980 PPSAHPPPLQLMPQSQPLPSS-----PAQPPG---LTQSQNLP---PPPASHPPTGLHQV 1028
Query: 1766 AYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTST 1825
A PQP ++H P PGGP +T PT S+S
Sbjct: 1029 A-----PQPPFAQH---PFVPGGPPPITPPTCPSTS------------------------ 1056
Query: 1826 TTVEHAPIWRPGTEQSSGSSGSSGGGG---GSSSRP-------------ASHSHAHQHSP 1869
P PGT SG++ GG G SS P A + P
Sbjct: 1057 -----TPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111
Query: 1870 ISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLG 1929
SP + + PS H + ++ + R+ P+ G
Sbjct: 1112 RSPSPEPTVVDTPS--HASQSARFYKHLDRGYNSCARTDLYFMPL-------------AG 1156
Query: 1930 GTLDGVYPTLMEPVLLPKEAPRVARPERPR---------------ADTGHAFLAKPPARS 1974
L +E +EA + AR ER R + A A A
Sbjct: 1157 SKLAKKREEAIEKA--KREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 1214
Query: 1975 G------LEPASSPSKGSEPRP----LVPPVSGHATIA-RTPAKNLAPHHASP----DPP 2019
G L EP P VPP G T A RT ++ PH SP P
Sbjct: 1215 GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 1274
Query: 2020 APPASASDP-----------------HRE--KTQSKPFSIQELELRSLGYHGSSYSPEGV 2060
P + +DP RE + + + I+E ELR G P +
Sbjct: 1275 YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 1334
Query: 2061 EPVSPVSSP--------SLTHDKGLPKH--------LEELDKSHLE---GELRPKQPGPV 2101
+P+ P ++P +LT H L L++ L +LRP+ P
Sbjct: 1335 DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 1394
Query: 2102 KLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVT-LAQHISEVITQDYTRH-HP 2159
+L E H + L + + P H + + L H + + Q HP
Sbjct: 1395 RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 1454
Query: 2160 --QQLSAPLPAPLYSFPGASCPVLDLRRPPSD 2189
L+A + +P + P L +PP +
Sbjct: 1455 LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHE 1486
Score = 39.7 bits (91), Expect = 0.038
Identities = 73/314 (23%), Positives = 107/314 (34%), Gaps = 36/314 (11%)
Query: 1969 KPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDP 2028
K A+ E ASSP K S R S RT +K S P S S+
Sbjct: 630 KKSAKKVKEEASSPLK-SNKRQREKVASDTEEADRTSSKKTKTQEISR-----PNSPSEG 683
Query: 2029 HREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSH 2088
E + S RS+ GSS P+ ++ + +SPS+ P+ E S
Sbjct: 684 EGESSDS----------RSVNDEGSS-DPKDIDQDNRSTSPSIPS----PQDNESDSDSS 728
Query: 2089 LEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISE 2148
+ ++ QP ++ + P P S P +P L T V
Sbjct: 729 AQQQMLQAQPPALQAP------TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP--- 779
Query: 2149 VITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSE 2208
T + PQ +AP+P P L +RPPS P P P + S
Sbjct: 780 --TASQAPNQPQAPTAPVPHTHIQ----QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 2209 GGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKS 2268
G +P + + G G G + + PG + P G+ + +
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893
Query: 2269 PGNTSQPPAFFSKL 2282
P + Q PA S L
Sbjct: 894 PHTSLQLPASQSAL 907
Score = 33.9 bits (76), Expect = 2.1
Identities = 12/24 (50%), Positives = 19/24 (79%)
Query: 1796 TTTSSSERERDRDRERDRDREREK 1819
T ++++++DR+RDRDREREK
Sbjct: 2 TADKDKDKDKEKDRDRDRDREREK 25
Score = 32.0 bits (71), Expect = 7.9
Identities = 12/45 (26%), Positives = 28/45 (62%)
Query: 491 GKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEK 535
G +++++ ++ +++ + R +E + EKEKE+E E+E E+
Sbjct: 1156 GSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 91.7 bits (226), Expect = 8e-18
Identities = 180/807 (22%), Positives = 279/807 (34%), Gaps = 165/807 (20%)
Query: 432 WSEQEKETFREKFMQHPKNFGLIAS-FLERKTVAECVLYYYLTKKN-ENYKSLVRRSYRR 489
W+E E + F + Q+ KNF I L K E + +YY KK E S R +RR
Sbjct: 396 WTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASSRAHRRHRR 455
Query: 490 RGKSQQQQQQQQQQQQQQQQQP-------MPRSSQEEKDEKEKEKEAE------------ 530
+ ++ + + +P + +S+++ D ++ E+E +
Sbjct: 456 QAVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTS 515
Query: 531 ----------------------KEEEKPEVENDKEDL------LKEKTDDTSGEDNDEKE 562
K E P +E + +KE+ D SG+ +
Sbjct: 516 KDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTR 575
Query: 563 AVASKGRKTANSQGRRKGRITRS-MANEANSEEAITPQQSAELASMELNESSRWTEEEME 621
S+G + GR+K + + N + + + S AS N+S + E
Sbjct: 576 R--SRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDS------KAE 627
Query: 622 TAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARR 681
T KK A+ V + S K+ KRQ + K+ + E R
Sbjct: 628 TVKKS-----------AKKVKEEASSPLKS-----NKRQ-------REKVASDTEEADRT 664
Query: 682 KKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPAT 741
KK ++E + P + E E+S ++ +++ G+ P+
Sbjct: 665 SSKKTK---TQEISRPNSPSEGEGESS-----------DSRSVNDEGSSDPKD-----ID 705
Query: 742 VNNSSDTESIPSPH-TEAAKDTGQNGP----KPPATLGADGPPPGPPTPPPEDIPAPTE- 795
+N S + SIPSP E+ D+ +PPA G P P + PP PT
Sbjct: 706 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 765
Query: 796 PTPASEAT---GAPTPPPAPPSPSAPPPVVPKEEKEEETAAAP--PVEEGEEQKPPAAEE 850
PTP++ A G+PT AP P AP VP ++ A P P P
Sbjct: 766 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP 825
Query: 851 LAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAE---------KKEGGSG 901
L TG A +P + P G+ + G L + G
Sbjct: 826 LQPLTGSAGQP----SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQG 881
Query: 902 RATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPL 961
+A S A S ++ +++ + + L P P + P PQ P
Sbjct: 882 QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA 941
Query: 962 DLKQLKQRAAAIP-PIVTKVHEPPREDAAP-----TKPAPPAPPPPQNLQPESDAPQQPG 1015
+ P P + PP P T P A PPP L P+S
Sbjct: 942 PQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSP 1001
Query: 1016 SSPRGKSRS---PAPPAD-------KEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVP 1065
+ P G ++S P PPA + A +P F A+ +PG PP T P P
Sbjct: 1002 AQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF-----AQHPFVPGGPPPIT---PPTCP 1053
Query: 1066 PREVIKASP--HAPDPSAFSYAPPGH-------PLPL------GLHDTARPVLPRPP--T 1108
A P A P + + A G PLP L D P P PP +
Sbjct: 1054 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113
Query: 1109 ISNPPPLISSAKHPSVLERQIGAISQG 1135
S P ++ + H S R + +G
Sbjct: 1114 PSPEPTVVDTPSHASQSARFYKHLDRG 1140
Score = 47.8 bits (112), Expect = 1e-04
Identities = 87/379 (22%), Positives = 132/379 (34%), Gaps = 58/379 (15%)
Query: 1802 ERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASH 1861
ERER++++E++R+RERE+ E + SS G S P
Sbjct: 1181 EREREKEKEKERERERERE-----------------REAERAAKASSSAHEGRLSDPQLS 1223
Query: 1862 SHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSP-VRPAATF 1920
H P P + +T + T E + P V+ T+ + P P
Sbjct: 1224 GPGHMRPSFEPPPTTIAAVPPYIGPDT--PALRTLSEYARPHVMSPTNRNHPFYMPLNPT 1281
Query: 1921 PP--ATHCPLGGTLDGVYPTLMEPVLLPKE-APRVARPERPRADTGHAFLAKPPARSGLE 1977
P A H P L V PT+ E L +E R R R F KPP L
Sbjct: 1282 DPLLAYHMP---GLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLH 1338
Query: 1978 PASSPSK--GSEPRPLVPPVSGHATIARTPAKNLAPH-HASPDPPAPPASASDPHREKTQ 2034
PA++P + +PP +G PH AS P P Q
Sbjct: 1339 PAANPMEHFARHSALTIPPTAG-------------PHPFASFHPGLNPLERERLALAGPQ 1385
Query: 2035 SKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELR 2094
+P L + H + +P++ + ++T P H + SH+ L
Sbjct: 1386 LRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVT-----PHHHQH---SHIHSHLH 1437
Query: 2095 PKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQ--HISEVITQ 2152
Q P+ G P + PL ++ P L P G L Q H E++
Sbjct: 1438 LHQQDPLHQGSAGPVHPLVDPL-----TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRH 1492
Query: 2153 D-YTRHHPQQLSAPLPAPL 2170
+ +P+ L +P P+
Sbjct: 1493 PVFGTPYPRDLPGAIPPPM 1511
Score = 43.5 bits (101), Expect = 0.003
Identities = 197/932 (21%), Positives = 300/932 (32%), Gaps = 229/932 (24%)
Query: 1405 KTQALGPLKL-KPAHEGLVATVKEAGRSIHEIPREELRHTPELPLAPRPLKEGSITQGTP 1463
K +A PLK K E + + +EA R+ + + + P P EG +
Sbjct: 637 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEG----EGESSDSRS 692
Query: 1464 LKYDTGASTTGSKKHDVRSLIGSPGRTFPPV-HPLDVMADARALERACYEESLKSRPGTA 1522
+ D G+S D RS T P + P D +D+ + + ++ L+++P
Sbjct: 693 VN-DEGSSDPKDIDQDNRS-------TSPSIPSPQDNESDS---DSSAQQQMLQAQPPAL 741
Query: 1523 SSSGG--SIARGAPVIVPELGKPRQSP--LTYEDHGAPFAGHLPRGSPVTTREPTPRL-- 1576
+ G AP P+L P +P G+P A P P P P
Sbjct: 742 QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN-QPQAPTAPVPHTHI 800
Query: 1577 -QEGSLSSSKASQD------------RKLTSTPREIAKSPHSTVPEH------------- 1610
Q +L + + LT + + + H+ P H
Sbjct: 801 QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 860
Query: 1611 ----HPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPR------ 1660
HP P P+ + G + A+ TS+ A + PR
Sbjct: 861 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920
Query: 1661 ------HLAPNPTYP---------HLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHN 1705
H+ P PT P H +PP+L P + ++S HH
Sbjct: 921 APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH- 979
Query: 1706 AATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRL 1765
+A ++ P SS A P G L+Q +LP PP P T + ++
Sbjct: 980 PPSAHPPPLQLMPQSQPLPSS-----PAQPPG---LTQSQNLP---PPPASHPPTGLHQV 1028
Query: 1766 AYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTST 1825
A PQP ++H P PGGP +T PT S+S
Sbjct: 1029 A-----PQPPFAQH---PFVPGGPPPITPPTCPSTS------------------------ 1056
Query: 1826 TTVEHAPIWRPGTEQSSGSSGSSGGGG---GSSSRP-------------ASHSHAHQHSP 1869
P PGT SG++ GG G SS P A + P
Sbjct: 1057 -----TPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 1111
Query: 1870 ISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLG 1929
SP + + PS H + ++ + R+ P+ G
Sbjct: 1112 RSPSPEPTVVDTPS--HASQSARFYKHLDRGYNSCARTDLYFMPL-------------AG 1156
Query: 1930 GTLDGVYPTLMEPVLLPKEAPRVARPERPR---------------ADTGHAFLAKPPARS 1974
L +E +EA + AR ER R + A A A
Sbjct: 1157 SKLAKKREEAIEKA--KREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 1214
Query: 1975 G------LEPASSPSKGSEPRP----LVPPVSGHATIA-RTPAKNLAPHHASP----DPP 2019
G L EP P VPP G T A RT ++ PH SP P
Sbjct: 1215 GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 1274
Query: 2020 APPASASDP-----------------HRE--KTQSKPFSIQELELRSLGYHGSSYSPEGV 2060
P + +DP RE + + + I+E ELR G P +
Sbjct: 1275 YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 1334
Query: 2061 EPVSPVSSP--------SLTHDKGLPKH--------LEELDKSHLE---GELRPKQPGPV 2101
+P+ P ++P +LT H L L++ L +LRP+ P
Sbjct: 1335 DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 1394
Query: 2102 KLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVT-LAQHISEVITQDYTRH-HP 2159
+L E H + L + + P H + + L H + + Q HP
Sbjct: 1395 RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 1454
Query: 2160 --QQLSAPLPAPLYSFPGASCPVLDLRRPPSD 2189
L+A + +P + P L +PP +
Sbjct: 1455 LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHE 1486
Score = 39.7 bits (91), Expect = 0.038
Identities = 73/314 (23%), Positives = 107/314 (34%), Gaps = 36/314 (11%)
Query: 1969 KPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDP 2028
K A+ E ASSP K S R S RT +K S P S S+
Sbjct: 630 KKSAKKVKEEASSPLK-SNKRQREKVASDTEEADRTSSKKTKTQEISR-----PNSPSEG 683
Query: 2029 HREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSH 2088
E + S RS+ GSS P+ ++ + +SPS+ P+ E S
Sbjct: 684 EGESSDS----------RSVNDEGSS-DPKDIDQDNRSTSPSIPS----PQDNESDSDSS 728
Query: 2089 LEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISE 2148
+ ++ QP ++ + P P S P +P L T V
Sbjct: 729 AQQQMLQAQPPALQAP------TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP--- 779
Query: 2149 VITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSE 2208
T + PQ +AP+P P L +RPPS P P P + S
Sbjct: 780 --TASQAPNQPQAPTAPVPHTHIQ----QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 2209 GGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKS 2268
G +P + + G G G + + PG + P G+ + +
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893
Query: 2269 PGNTSQPPAFFSKL 2282
P + Q PA S L
Sbjct: 894 PHTSLQLPASQSAL 907
Score = 33.9 bits (76), Expect = 2.1
Identities = 12/24 (50%), Positives = 19/24 (79%)
Query: 1796 TTTSSSERERDRDRERDRDREREK 1819
T ++++++DR+RDRDREREK
Sbjct: 2 TADKDKDKDKEKDRDRDRDREREK 25
Score = 32.0 bits (71), Expect = 7.9
Identities = 12/45 (26%), Positives = 28/45 (62%)
Query: 491 GKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEK 535
G +++++ ++ +++ + R +E + EKEKE+E E+E E+
Sbjct: 1156 GSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 90.1 bits (222), Expect = 2e-17
Identities = 148/624 (23%), Positives = 213/624 (34%), Gaps = 100/624 (16%)
Query: 505 QQQQQQPMPRSSQEEKDEKE---KEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEK 561
+++ +P+ S E+DEKE +E+E+ +EEE+ E E ++ED + +DD +ND++
Sbjct: 1020 RRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE 1079
Query: 562 EAVASKG--RKTANSQGRRKGRITRSMANEANSEEAITPQQSAEL-ASMELNESSRWTEE 618
+ S+ + +S I S A +S E+ +S+E +S E + SS EE
Sbjct: 1080 DTALSEASEKDEGDSDEEETVSIVTSKAEATSSSES---SESSEFESSSESSPSSSEDEE 1136
Query: 619 EMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERN 678
E+ +AR +E ++ + +M E +
Sbjct: 1137 EV----------------VAR-----------------------EEEEEEEEEEMVAEES 1157
Query: 679 ARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSG 738
+ EEAA P A G EEE+ E EA+ E
Sbjct: 1158 MASAGPEDFEQDGEEAALAPGAP-----AVDSLGMEEEVDIETEAVAPEERPSMLDEPPL 1212
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTP 798
P V +D+ P + + P+PPA PP P P D+ EP P
Sbjct: 1213 PVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEV--EPEP 1270
Query: 799 ASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKA 858
PP PP P PP P+ E + + + P E E PP L K+
Sbjct: 1271 PMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKS 1330
Query: 859 EEPVKSECTEEAE---EGPAKGKDAEAAEATAE----GALKAEKKEGGSGRATTAKSSGA 911
+ T E G + G + + A GG R S
Sbjct: 1331 QSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFT 1390
Query: 912 PQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAA 971
P S+ S G R +L TG P P PL L
Sbjct: 1391 PTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLP-LPLPL-------- 1441
Query: 972 AIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADK 1031
A+P ++ P P PAP A PP P P +P SP P
Sbjct: 1442 ALPAVLRAQARAP-TPLPPLLPAPLASCPP----PMKRKPGRPRRSPPSMLSLDGP---- 1492
Query: 1032 EAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPL 1091
+P A E LPG P PV P S H P + G P
Sbjct: 1493 -LVRPPAGAALGRELLLLPGQPQT-------PVFP------STHDPRTVTLDFRNAGIPA 1538
Query: 1092 PLGLHDTARPVLPRPPTISNPPPL 1115
P P+ P+PP PPP+
Sbjct: 1539 P------PPPLPPQPPPPPPPPPV 1556
Score = 61.6 bits (148), Expect = 9e-09
Identities = 80/366 (21%), Positives = 131/366 (35%), Gaps = 60/366 (16%)
Query: 824 KEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAA 883
++E EE A EE E+ +++ E+ SE +E+ E + +
Sbjct: 1044 EQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIV 1103
Query: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSS-ATCSADEVDEAEGGDKNRLLSPRP 942
+ AE +E E +++ S + +D + A +E +E E + + S P
Sbjct: 1104 TSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGP 1163
Query: 943 SLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQ 1002
G+ A A +D +++ V P D PP P +
Sbjct: 1164 EDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDE------PPLPVGVE 1217
Query: 1003 NLQPESDAPQQPGSSPRGKSR-SPAPPADKEAEKPVFFPAFAAEAQ-KLPGDPPCWTSGL 1060
+ P++PG S G SP PPA + +P P A E ++ +PP L
Sbjct: 1218 EPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMM---L 1274
Query: 1061 PFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPL--ISS 1118
P P+ P PLP PRPP +PPP +
Sbjct: 1275 PLPLQP-----------------------PLPP----------PRPPRPPSPPPEPETTD 1301
Query: 1119 AKHPSVLERQI------------GAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPK 1166
A HPSV + G++++ S + VP + + P+ + GL L
Sbjct: 1302 ASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTET-VPATPGGEPPLSGGSSGLSLSSPQV 1360
Query: 1167 KLAPFS 1172
+PFS
Sbjct: 1361 PGSPFS 1366
Score = 57.0 bits (136), Expect = 2e-07
Identities = 117/503 (23%), Positives = 158/503 (31%), Gaps = 119/503 (23%)
Query: 767 PKPPATLGADGPPPGPPTPPP-------------EDIPAPTEPTPASEATGA-------- 805
P+ AT A PPP TP P P P E A+ A GA
Sbjct: 372 PQDSATF-AHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRR 430
Query: 806 -PTPPPAPPS-------PSAPPPVVPKEEKEEETAAAPPVEEGEE----------QKPPA 847
P PPP PP+ P PP P + E P E + PA
Sbjct: 431 APAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPA 490
Query: 848 AEELAVDT--GKAEEPVKSECTE-------------EAEEGPAKGKDAEAAEATAEGALK 892
E D+ + E +K + T+ + E P ++ + G
Sbjct: 491 GPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNS 550
Query: 893 AEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPR 952
G + ++ S+G +D + +DE +E + G L PRP DP
Sbjct: 551 QPGFRGPTPPSSRPSSTGL-EDISPTPLPDSDEDEELDLG-----LGPRPPPEPGPPDPA 604
Query: 953 ANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPR---------EDAAPTKPAPPAP-PPPQ 1002
S + L + R P K+ E + +D P+ P A P P
Sbjct: 605 GLLSQTAEVALDLVGDRT----PTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM 660
Query: 1003 NLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPF 1062
+ P + A P P PP P FP LP PP F
Sbjct: 661 VVTPGAAAVAAPSVL---APTLPLPP-------PPGFP-------PLPPPPPPPPPQPGF 703
Query: 1063 PVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPL------I 1116
P+PP + P P P+ + P PLP A P +P PP + PP +
Sbjct: 704 PMPP--PLPPPPPPPPPAHPAVTVPPPPLP------APPGVPPPPILPPLPPFPPGLFPV 755
Query: 1117 SSAKHPSVLERQIGAISQGMSVQLHV-----------PYSEHAKAPVGPVTMGLPLPMDP 1165
VL Q G + +Q V PY A + GL P
Sbjct: 756 MQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLP 815
Query: 1166 KKLAPFSGVKQEQLSPRGQAGPP 1188
PFS RGQ PP
Sbjct: 816 PYRGPFS--LSNSGPGRGQHWPP 836
Score = 55.5 bits (132), Expect = 7e-07
Identities = 39/122 (31%), Positives = 44/122 (36%), Gaps = 9/122 (7%)
Query: 723 ALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKP----PATLGADGP 778
AL G+ P E ++ D E I +A T + PKP P P
Sbjct: 614 ALDLVGDRTPTSEKMDEGQQSSGEDME-ISDDEMPSAPITSADCPKPMVVTPGAAAVAAP 672
Query: 779 ----PPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAA 834
P P PPP P P P P G P PPP PP P PPP P A
Sbjct: 673 SVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732
Query: 835 PP 836
PP
Sbjct: 733 PP 734
Score = 52.8 bits (125), Expect = 4e-06
Identities = 119/527 (22%), Positives = 162/527 (30%), Gaps = 103/527 (19%)
Query: 1756 GTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTK--PTTTSSSERERDRDRERDR 1813
GTP T P PFS S S P P++L P T + R + +
Sbjct: 272 GTPLT--------PRLGTPFSQDSSYSSRQPT-PSYLFSQDPAVTFKARRHESKFTDAYN 322
Query: 1814 DREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPR 1873
R + S A S G+ GG GGSS P P+
Sbjct: 323 RRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFK---------AQPQ 373
Query: 1874 TQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCP-----L 1928
P T G +A P P A FPP P
Sbjct: 374 DSATFAHTPPPAQATPAPGFKSAFSPYQT-------------PVAHFPPPPEEPTATAAF 420
Query: 1929 GGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEP 1988
G G + P LP P E+P G PP + +E P+ G P
Sbjct: 421 GARDSGEFRRAPAPPPLPPAEPLAK--EKPGTPPG----PPPPDTNSMELGGRPTFGWSP 474
Query: 1989 RPLVPPVSGHATIARTPAKNLAPHHASP--------DPPAPPASASDPHRE---KTQSKP 2037
P P G T+ +PA PH + + +P + + + P
Sbjct: 475 EPCDSP--GTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSP 532
Query: 2038 FSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGL-PKHLEELDKSH-LE---GE 2092
S +L L G++ P P P S PS T + + P L + D+ L+ G
Sbjct: 533 ISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGP 592
Query: 2093 LRPKQPGPVKLGGEAAHLPHLR-PLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVIT 2151
P +PGP G + + L + +S + G ++ + S IT
Sbjct: 593 RPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPIT 652
Query: 2152 QDYTRHHPQQLSAPLPAPLYSFPGASC--------PVLDLRRPPSDLYLPPPDHGAPARG 2203
SA P P+ PGA+ P L L PP LPPP P
Sbjct: 653 -----------SADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPP--- 698
Query: 2204 SPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYP 2250
P+P G P+ PP P H V P
Sbjct: 699 ----------PQP--------GFPMPPPLPPPPPPPPPAHPAVTVPP 727
Score = 50.1 bits (118), Expect = 3e-05
Identities = 34/126 (26%), Positives = 46/126 (36%), Gaps = 16/126 (12%)
Query: 703 EEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDT 762
E+M+ S E+ + + E A + +C P V + + PS
Sbjct: 626 EKMDEGQQSSGEDMEISDDEMPSAP---ITSADCPKPMVVTPGAAAVAAPSVLAPTL--- 679
Query: 763 GQNGPKPPATLGADGPPPGPPTPP------PEDIPAPTEPTPASEATGAPTPPPAPPSPS 816
P PP PPP PP PP P +P P P P + PPP P P
Sbjct: 680 ----PLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG 735
Query: 817 APPPVV 822
PPP +
Sbjct: 736 VPPPPI 741
Score = 40.4 bits (93), Expect = 0.022
Identities = 26/75 (34%), Positives = 29/75 (38%), Gaps = 5/75 (6%)
Query: 778 PPPGPPTPPPEDIPAPTEPT--PASEATGAPTPPPAPPSPSAPPPVVPKE---EKEEETA 832
PPP PP PPP P P EPT P E PP P V + K
Sbjct: 1540 PPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPW 1599
Query: 833 AAPPVEEGEEQKPPA 847
PP + E+ PPA
Sbjct: 1600 RRPPKKRHEDLVPPA 1614
Score = 37.4 bits (85), Expect = 0.19
Identities = 38/121 (31%), Positives = 47/121 (38%), Gaps = 28/121 (23%)
Query: 765 NGP--KPPA--TLGAD-----GPPPGPPTPPPED------------IPAPTEPTPASEAT 803
+GP +PPA LG + G P P P D IPAP P P
Sbjct: 1490 DGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQ--- 1546
Query: 804 GAPTPPPAPPSPSAPPPVVPKE-EKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPV 862
P PPP PP P P + KE + + + A PP G ++ ELA G P
Sbjct: 1547 --PPPPPPPP-PVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPP 1603
Query: 863 K 863
K
Sbjct: 1604 K 1604
Score = 37.0 bits (84), Expect = 0.25
Identities = 105/444 (23%), Positives = 143/444 (32%), Gaps = 86/444 (19%)
Query: 1797 TTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSS 1856
T S E+D E D D E SI+TS +++ SS SS SS
Sbjct: 1081 TALSEASEKD---EGDSDEEETVSIVTSKA-------------EATSSSESSESSEFESS 1124
Query: 1857 RPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMK----------GIITAVEPSTPTV-- 1904
+S S + + R ++ ++ ++ M G A+ P P V
Sbjct: 1125 SESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDS 1184
Query: 1905 --------LRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPE 1956
+ + + + RP+ P + D P E L +E + PE
Sbjct: 1185 LGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPP--EEPGLSQEGAMLLSPE 1242
Query: 1957 RPRADTGHAFLAKPPARSGLEPASSPSKGSE----------------------PRPLVPP 1994
P + A+PP L P +P E PRP PP
Sbjct: 1243 PPAKEVE----ARPP----LSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP 1294
Query: 1995 VSGHATIA---RTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYH 2051
T A P + LA H P + A E + P L S G
Sbjct: 1295 PEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLS 1354
Query: 2052 GSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLP 2111
SS G P SPSL+ GLP+ D S P GP+ L LP
Sbjct: 1355 LSSPQVPGSPFSYPAPSPSLS-SGGLPR-TPGRDFSFTPTFSEPS--GPLLL--PVCPLP 1408
Query: 2112 HLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLP-APL 2170
R S P +SP+L + L + V+ Q AP P PL
Sbjct: 1409 TGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLR--------AQARAPTPLPPL 1460
Query: 2171 YSFPGASCPVLDLRRPPSDLYLPP 2194
P ASCP R+P PP
Sbjct: 1461 LPAPLASCPPPMKRKPGRPRRSPP 1484
Score = 33.5 bits (75), Expect = 2.7
Identities = 66/312 (21%), Positives = 98/312 (31%), Gaps = 33/312 (10%)
Query: 1735 PRGIIDLSQVPHLPVLVPPTPGTPATAMDRL--AYLPTAPQPFSSRHSSSPLSPGGPTHL 1792
P ++ L P LP PP P +P + ++ P+P + H P +PG L
Sbjct: 1270 PPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHP--PHTPGLCGSL 1327
Query: 1793 TKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSG--SSGG 1850
K +T + + + S+ V +P P S S G + G
Sbjct: 1328 AKSQSTETVPATPGGEPPLSGG---SSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPG 1384
Query: 1851 GGGSSSRPASHSHAHQHSPISPRTQDALQQRPS-----VLHNTGMKGIITAVEP---STP 1902
S + S P+ P +R VL TG+ + P + P
Sbjct: 1385 RDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALP 1444
Query: 1903 TVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADT 1962
VLR+ + + P P CP P P +L + P
Sbjct: 1445 AVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP------------ 1492
Query: 1963 GHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPP 2022
L +PPA + L G P+ P T+ P P PP PP
Sbjct: 1493 ----LVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPP 1548
Query: 2023 ASASDPHREKTQ 2034
P E T+
Sbjct: 1549 PPPPPPPVEPTK 1560
Score = 32.7 bits (73), Expect = 4.6
Identities = 36/124 (29%), Positives = 52/124 (41%), Gaps = 13/124 (10%)
Query: 95 LGKSEMEFIESKRPRLELLPDPLLRPSPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPP 154
LG E IE++ E P L P + +PA S + ++ L+ + + P PP
Sbjct: 1185 LGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPP 1244
Query: 155 HTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPV 214
E+E PP LS E ++ V+ E M+ L Q PP P +P
Sbjct: 1245 AK--EVEARPP-LSPERAPEHDLEVEPEPPMM------LPLPLQP----PLPPPRPPRPP 1291
Query: 215 SPPP 218
SPPP
Sbjct: 1292 SPPP 1295
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 88.2 bits (217), Expect = 9e-17
Identities = 125/490 (25%), Positives = 163/490 (33%), Gaps = 93/490 (18%)
Query: 779 PPGPPTPPPEDIPAPTEPTPASEAT-------------GAPTPPPAP---PSPSAPPPVV 822
PPG P PPP PA A+ A GA P AP P+ ++ PP
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPAS 88
Query: 823 PKEEK---EEETAAAP------------PVEEGEEQKPPAAEELAVDTGKAEEPVKSECT 867
+ E+ + T+ P P G++ +AEE V GKA E K
Sbjct: 89 GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE-TVARGKATEAPKRSAL 147
Query: 868 EEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVD 927
G +A E G R + P + + SA E
Sbjct: 148 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 207
Query: 928 EAE-----------GGDKNR------------LLSPRPSLLTPTGDPRANASPQKPLDLK 964
E GG R L SP S + G PRA A P +P
Sbjct: 208 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP---- 263
Query: 965 QLKQRAAAIPPIVTKVHEPPREDAAP----------TKPAPPAPPPPQNLQPESDAPQQP 1014
+ K A PP VT PPR+DAAP P+P APP P P P
Sbjct: 264 KPKGLQALRPPQVT----PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP 319
Query: 1015 GSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASP 1074
+ P + S P + + P + A P PP +PP + + P
Sbjct: 320 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA------LALPPLQAPPSPP 373
Query: 1075 HAPDPSAFSYAPPGHPLPLGLHDTARPVLPRP-PTISNP------PPLISSAKHPSVLER 1127
+P S + P P L +H P P P P + P PP+ SA PS
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Query: 1128 QIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGP 1187
+ A L VP S A P+ P P P P K +P A P
Sbjct: 434 SLAA------PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487
Query: 1188 P-ESLGVPTA 1196
P ++L P A
Sbjct: 488 PLQALPSPPA 497
Score = 70.1 bits (170), Expect = 3e-11
Identities = 119/506 (23%), Positives = 180/506 (35%), Gaps = 92/506 (18%)
Query: 751 IPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAP--TEPTPASEATGAPT- 807
+ P +AA G P AT PP P + +P+P T P+ A+ + G+PT
Sbjct: 276 VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335
Query: 808 ---------PPPAP---PSPSAPPPV-VPKEEKEEETAAAPPVEEGEEQKPPAAEELAVD 854
PP +P P P APP + +P + A+PP+ P A LAV
Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395
Query: 855 TGKA------EEPVKSECTEEAEE--GPAKGKDAEAAEATAEGALKAEKKEGGSGRATTA 906
+A PV++ + A P+ ++A + A L+ S A+
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP----SPPASPP 451
Query: 907 KSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDL--K 964
S A + +A + +L P P P A P P +
Sbjct: 452 MSPSATPPPQAPPPLAAPPL---------QLAKPPPQAPPALATPPLQALPSPPASFPGQ 502
Query: 965 QLKQRAAAIP--PIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKS 1022
+A++P P+ T + P AAP PP+PP LQ AP++P
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ----APRRP-------- 550
Query: 1023 RSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAF 1082
P P D P A A PG PP PP ++ PD +
Sbjct: 551 --PTPGPDTSVSGPRLTLALA------PGPPP----------PPSRSPSSTLSGPDLAGH 592
Query: 1083 SYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLIS-SAKHPSVLERQIGAISQGMSVQLH 1141
S + P L +D+ P ++PPP +A HP+ A S+G + L
Sbjct: 593 SSSATSTPEELRGYDSG----PEGGAAASPPPDAELAACHPA-------AWSRGPAPPLA 641
Query: 1142 VPYSEHAKAPVGPVT-----MGLPLPMD---PKKLAPFSGVKQEQLSPRGQAGPPESLGV 1193
+ A P P T GL + P+ P G SP G +G + G
Sbjct: 642 FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP-GTSGGKAAAGA 700
Query: 1194 PTAQEASVLRGTALGSVPGGSITKGI 1219
+ + LG +P G++ +
Sbjct: 701 GAGASSRSPKQARLGELPLGALQASV 726
Score = 63.2 bits (152), Expect = 3e-09
Identities = 136/566 (24%), Positives = 188/566 (33%), Gaps = 135/566 (23%)
Query: 1753 PTPGTPATAMDRLAYLPTA----PQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRD 1808
PTPGTP+ AM R + P+P S P PT + + +S+SE
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSAR------PRPPTEGPRKSVSSASEHSTTEP 211
Query: 1809 RERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSG--SSGGGGGSSSRPASHSHAHQ 1866
R R L RP + S S+ SS G S+R + AH
Sbjct: 212 SPAARRRPSAGGGLQ-----------RPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 260
Query: 1867 HSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT------- 1919
P P+ AL+ P V K A+ P + + L + S S+P P+A
Sbjct: 261 SQP-KPKGLQALRP-PQV--TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP 316
Query: 1920 FPPATH-----CPLGG-TLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLA--KPP 1971
PPAT LG TL + L P L P P P+ P A A PP
Sbjct: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP---PQAPPALALPPLQAPPSPP 373
Query: 1972 ARSGLEPASSPSKGSE--------------------PRPLVPPVSGHATIARTPAKNLAP 2011
A L P ++PS + P PP S + + TP P
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Query: 2012 HHASPDPPAPPASASDPHREKTQSKPFS---------------------------IQELE 2044
A+P PP+ + P + + P +Q L
Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493
Query: 2045 LRSLGYHGSS-YSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKS-----HLEGELRPKQP 2098
+ G + +SP P+SP+++P L L ++ S L+ RP P
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Query: 2099 GP-VKLGGEAAHLPHLRPLPESQPSSSP-LLQTAPGVKGHQRVVTLAQH----------- 2145
GP + G L L P P PS SP + P + GH T
Sbjct: 554 GPDTSVSGPRLTLA-LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612
Query: 2146 ---ISEVITQDYTRHHPQQLS--------------APLPAPLYSFPGAS---CPVLDLRR 2185
S + HP S APLP P + PG++ C + +
Sbjct: 613 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 672
Query: 2186 PPSDLYLPPPDHGAPARGSPHSEGGK 2211
P S P P SP + GGK
Sbjct: 673 PESATPAPGALDPGP---SPGTSGGK 695
Score = 60.1 bits (144), Expect = 3e-08
Identities = 118/465 (25%), Positives = 158/465 (33%), Gaps = 117/465 (25%)
Query: 681 RKKKKAPAAASE------EAAFPPVVEDEEMEASGVSG--NEEEMVEEAEALHASGNEVP 732
R +APA S+ +A PP V +A+ G + + + + S + P
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310
Query: 733 RGEC--SGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPT---PPP 787
+ S PAT + + T S+ SP +A T P PP + A PP PP PP
Sbjct: 311 SLQTLPSPPATPPSQATT-SLGSPTLQA---THSFLPSPPLSPLATPPPQAPPALALPPL 366
Query: 788 EDIPAPTEPTPASE-ATGAP---------------TPPPAPP-----SPSAPPPVVPKEE 826
+ P+P P S AT +P +PPP+PP SP A PPV P
Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP--- 423
Query: 827 KEEETAAAPPVEEGEEQKPP--AAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAE 884
+A PP Q PP AA L V P S P+ +A
Sbjct: 424 -----SATPP-----SQAPPSLAAPPLQVPPSPPASPPMS---------PSATPPPQAPP 464
Query: 885 ATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL 944
A L+ K PQ + AT + P P
Sbjct: 465 PLAAPPLQLAKP--------------PPQAPPALATPPLQAL-------------PSPPA 497
Query: 945 LTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTK--VHEPPREDAAPTKPAPPAPPPPQ 1002
P +A SP L + L PP++ + PP A+PT AP PP P
Sbjct: 498 SFP---GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP- 553
Query: 1003 NLQPESDAPQQPGSSPR---GKSRSPAPPADKEAEKPVFFPAFA---AEAQKLPGDPPCW 1056
P S PR + P PP + + P A + A P + +
Sbjct: 554 -------GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606
Query: 1057 TSG-----LPFPVPPREVIKASPHA----PDPSAFSYAPPGHPLP 1092
SG P P E+ P A P P PG PLP
Sbjct: 607 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 651
Score = 47.8 bits (112), Expect = 1e-04
Identities = 169/713 (23%), Positives = 232/713 (32%), Gaps = 166/713 (23%)
Query: 1826 TTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVL 1885
T E AP R G ++S S G G + PA ++ P+S + + RP L
Sbjct: 69 TIPESAP--RAGPTRTSRPPAS---GRGERAPPAKNTSP---GPVSSPGRASGTTRPGPL 120
Query: 1886 HNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLL 1945
G KG+ + E TV R +T +P R A + G D PT P
Sbjct: 121 ---GQKGLRISAEE---TVARGKATEAPKRSALS--------AGARRDTSGPTPGTP--- 163
Query: 1946 PKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTP 2005
+P +AR R RA L +P + P P++G PR V S H+T +P
Sbjct: 164 ---SPAMAR--RSRAAGTEVGLPRPAPSARPRP---PTEG--PRKSVSSASEHSTTEPSP 213
Query: 2006 AKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSP 2065
A P ++ ++ S+ S L S G S P P
Sbjct: 214 AARRRP-------------SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 260
Query: 2066 VSSPSLTHDKGLPKHLEELDKSHLEGELRPKQP--GPVKLGGEAAHLPHLRPLPESQPSS 2123
S P PK L+ L + + P GP+ A P P P S P S
Sbjct: 261 -SQPK-------PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP-SAPPS 311
Query: 2124 SPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVL-- 2181
L + P Q +L + T + L +P +PL + P + P L
Sbjct: 312 LQTLPSPPATPPSQATTSLGSPTLQA-THSF-------LPSPPLSPLATPPPQAPPALAL 363
Query: 2182 -DLRRPPSDLYLPP------PDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSP 2234
L+ PPS PP P AP + H SP P+ P SP
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA--------PFSP 415
Query: 2235 PEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKK 2294
P P S SA P S++P + + PP ++ M S
Sbjct: 416 P---ASPPVSPSATPP---------------SQAPPSLAAPPLQVPPSPPASPPMSPSA- 456
Query: 2295 QEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIR 2354
T P ++ P ++ P L T QA+
Sbjct: 457 --------TPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPLQALP-------------- 493
Query: 2355 KALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHTLTSPGGGGKAKVSG 2414
SPP S P + SASLP + P+ ++ L +P
Sbjct: 494 ------------SPPASFPGQAPFSPSASLPMS-PLATPPPQAPPVLAAPLLQVPPSPPA 540
Query: 2415 RP---SSRKAKSPAP-----------GLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDR 2460
P + R+ +P P LA G PP S S L+
Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS--------TLSGPDLAGH 592
Query: 2461 PSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLL 2513
SSA STP + G ASPPP A P AW P P L
Sbjct: 593 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA-----AWSRGPAPPL 640
Score = 39.7 bits (91), Expect = 0.038
Identities = 76/338 (22%), Positives = 112/338 (33%), Gaps = 59/338 (17%)
Query: 2174 PGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVS 2233
P A P L RPP PPP A R + R P + +GG +
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG-------AT 69
Query: 2234 PPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSP-------GNTSQPPAFFSK--LTE 2284
PE G +R++ P R GE+ P++ S P T++P K
Sbjct: 70 IPESAPRAGPTRTSRPPASGR-GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128
Query: 2285 SNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQEHAS 2344
+ + + K E K+ + + PGT PA M RS+A A
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTP---SPA------MARRSRA----AG 175
Query: 2345 TNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHTLTSP 2404
T +GL P A + P P P + S+H+ T P
Sbjct: 176 TEVGL-------------------PRPAPSARP-----RPPTEGPRKSVSSASEHSTTEP 211
Query: 2405 GGGGKAKVSG-----RPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWED 2459
+ + S RP+SR S A L+S R + + P +
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271
Query: 2460 RPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGP 2497
RP P + L + +A+P P P+ S P
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 87.8 bits (216), Expect = 1e-16
Identities = 115/596 (19%), Positives = 243/596 (40%), Gaps = 79/596 (13%)
Query: 170 EELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQI 229
EEL + D + E+ +LKKK +L+E+ P+ +S +Q+
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKL-------------PLAESEKSEIQL 246
Query: 230 IYDENRKKAEAAHRILEGLGPQVEL-----PLYNQPSDTRQYHENIKINQAMRKKLILYF 284
E ++K E A +L PQV+ ++ Q + R+ + I
Sbjct: 247 NVKELKRKLERAKFLL----PQVQTNTLQEEMWRQEEELREQEKKI-------------- 288
Query: 285 KRRNHARKQWEQKFCQRYDQ-LMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQ 343
R K W Q+ R + M E+K+ R E R + KE + +E ++ E+R+Q
Sbjct: 289 --RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346
Query: 344 RELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDAD 403
E + + ++ ++ + + + + + + E++MR +++ D
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ---EERMWEQD 403
Query: 404 QQ-RIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKT 462
++ R K M +V K R+ M +++K +E+ MQ + + +
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEE 463
Query: 463 VAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDE 522
+ K+ EN + ++++ +Q+++ +Q++ Q+Q++ + ++ +D+
Sbjct: 464 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 523
Query: 523 KE----------KEKEAEKEEEKPEVEN----------DKEDLLKEKTDDTSGEDNDEKE 562
+E +EK E+E++ E E D+E+ +++KT + + D++E
Sbjct: 524 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 563 AVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEE--M 620
+ + R + +K R M E EE + Q+ M+ E W +EE
Sbjct: 584 KMREEERM---REREKKMREEEEMMRE--QEEKMQEQEE----KMQEQEEKMWEQEEKMQ 634
Query: 621 ETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKL-----KMEK 675
E +K + + W +M + + + K + ++K Q +++ +Q + KMEK
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK 694
Query: 676 ERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEV 731
+ + KK EE + + E + EE+M E+ E + E+
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Score = 87.8 bits (216), Expect = 1e-16
Identities = 103/543 (18%), Positives = 229/543 (42%), Gaps = 45/543 (8%)
Query: 166 RLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRS 225
R +E++ + +R+ + + +Q K+ +++++L E+ + E EK + +
Sbjct: 289 RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEE 348
Query: 226 LVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMR----KKLI 281
+Q ++ ++ E E + Q E L+ Q R+ + ++ + ++L
Sbjct: 349 QMQEQEEKMWEQEEKMREQEEKMWRQEER-LWEQEKQMREQEQKMRDQEERMWEQDERLR 407
Query: 282 LYFKRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIR 341
+R K WEQ R ++ M+ EKK E + +E ++RE +K E
Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE---KMQEEERIREREKKMREEEE 464
Query: 342 KQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYD 401
RE +E+MQ + + + + E + L EQE +++Q ++
Sbjct: 465 TMREQEEKMQKQ--EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW-------- 514
Query: 402 ADQQRIKFINMNGLMADPMKVYKDRQVMN----MWSEQEKETFREKFMQHPKNFGLIASF 457
+Q K + + K+++ ++ MW ++EK +E+ M +
Sbjct: 515 --EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER------ 566
Query: 458 LERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQ---QQQQQQQQQQQQQQQQPMPR 514
+E+KT + + +K + + R + R + + +Q+++ Q+Q+++ Q+Q
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 515 SSQEEKDEKEKEKEAEKEE----------EKPEVENDKEDLLK-EKTDDTSGEDNDEKEA 563
QEEK ++++EK E+EE E+ + KE L + EK + E++
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Query: 564 VASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETA 623
+ + + +K M E + E + E E E + EE+M+
Sbjct: 687 WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 624 KKGLLE-HGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRK 682
++ + E + W +M + + + K + ++K Q ++I +Q + ++E R +
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 683 KKK 685
++K
Sbjct: 807 EEK 809
Score = 72.4 bits (176), Expect = 5e-12
Identities = 94/480 (19%), Positives = 198/480 (41%), Gaps = 46/480 (9%)
Query: 169 KEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQ 228
+E++ + ++++ E M EQ+ ++++ EEE + E + + + + +
Sbjct: 416 QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQK 475
Query: 229 IIYDENRKKAEAAHRILEGLGPQVEL-----PLYNQPSDTRQYHENIKINQAM---RKKL 280
+EN + E + L Q E + Q + E I+ + M KK+
Sbjct: 476 --QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533
Query: 281 ILYFKRRNHARKQWEQKFCQRYDQLMEAW-------------EKKV----ERIENNPRRR 323
K R + WEQ+ R DQ + W EKK E++ R R
Sbjct: 534 WRQEKMREQEDQMWEQEEKMR-DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR 592
Query: 324 AKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQE 383
+E K+RE E + K +E +E+MQ + + E ++ E + + EQE
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ-EEKMQEQEEKMWEQEEKMWEQE 651
Query: 384 NLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREK 443
+ ++L L++ ++ + + K+++ ++ EQEK+T+ ++
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQ----EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707
Query: 444 FMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQ 503
M+ ++ E+K E + +K + + ++ + +++ +Q+++
Sbjct: 708 KMREEESM----REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Query: 504 QQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGED---NDE 560
+QQ+ P +E+ E EK +E EK E+ E D+E+ ++ + + G++ +
Sbjct: 764 MWEQQRLP---EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ 820
Query: 561 KEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEM 620
+E + + K + + G+ + E EE + Q E E E R EE+M
Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKM---QGQEEKMREQEEKMRGQEEKM 877
Score = 55.5 bits (132), Expect = 7e-07
Identities = 84/448 (18%), Positives = 188/448 (41%), Gaps = 64/448 (14%)
Query: 166 RLSKEELIQNMDRVDREI--TMVEQQISKLKKKQQQLEEEAAK-------PPEPEKPVSP 216
++ +EE I+ ++ RE TM EQ+ K++K+++ + E+ K P + EK
Sbjct: 445 KMQEEERIREREKKMREEEETMREQE-EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 217 PPIESKHRSL---VQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKIN 273
++ + + + I D+ + + + E ++ Q R + +
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 274 QAMRKKLILYFKRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAK-----ESK 328
+ +K K + +K W+Q+ R ++ M EKK+ E R + + E K
Sbjct: 564 EERMEK-----KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 618
Query: 329 VREYYEKQFPEIRKQRELQERM----------------QSRVGQRGSGLSMSAARSEHE- 371
++E EK + + K +E +E+M Q R+ ++ L E E
Sbjct: 619 MQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 678
Query: 372 VSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMN- 430
+ E + + EQE +EK+ ++ +D ++ R + + K+ ++ ++M
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQE---KKTWDQEKMREE----ESMREREKKMREEEEMMRE 731
Query: 431 ----MWSEQEK--ETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVR 484
M ++EK E E + Q K + E++ + E + +K + + +
Sbjct: 732 QEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE 791
Query: 485 RSYRRRGKSQQQQQQQQQQQQQQQQ----------QPMPRSSQEEKDEKEKEKEAEKEEE 534
+ + R + ++ + Q+++ + Q+++ Q QEEK ++EK +EE+
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 535 KPEVENDKEDLLKEKTDDTSGEDNDEKE 562
E +E+ ++E+ + G++ +E
Sbjct: 852 MEEKMQGQEEKMREQEEKMRGQEEKMRE 879
Score = 55.1 bits (131), Expect = 9e-07
Identities = 69/368 (18%), Positives = 162/368 (44%), Gaps = 60/368 (16%)
Query: 169 KEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQ 228
+EE ++ +R+ + ++ +++++++++E+ K E E+ + E K + +
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ--EEKMQEQEE 638
Query: 229 IIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRN 288
++++ K E ++ E Q LP + + HE ++ + M+++
Sbjct: 639 KMWEQEEKMWEQEEKMWE----QQRLP---EQKEKLWEHEKMQEQEKMQEQ--------- 682
Query: 289 HARKQWEQKFCQRYDQLME--AWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQREL 346
K WEQ+ ++ Q E W+++ R E + R R E K+RE E + K +E
Sbjct: 683 -EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER--EKKMREEEEMMREQEEKMQEQ 739
Query: 347 QERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQR 406
+E+MQ + E E+ E + + EQE + ++L L++ ++
Sbjct: 740 EEKMQEQ---------------EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK-- 782
Query: 407 IKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAEC 466
M + K+++ + M ++EK +E+ M+ + E+ E
Sbjct: 783 ---------MQEQEKIWEQEEKMR--DQEEKMRGQEEKMRGQE---------EKMRGQEE 822
Query: 467 VLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKE 526
++ K + + + + G+ ++ +++ Q Q+++ ++Q QEEK +++E
Sbjct: 823 KMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEE 882
Query: 527 KEAEKEEE 534
K +EE+
Sbjct: 883 KMRGQEEK 890
Score = 54.7 bits (130), Expect = 1e-06
Identities = 82/433 (18%), Positives = 173/433 (39%), Gaps = 42/433 (9%)
Query: 307 EAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAA 366
E +K E E P +++S+++ ++ ++ + + L ++Q+ L
Sbjct: 222 ELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNT------LQEEMW 275
Query: 367 RSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYKDR 426
R E E+ E + +QE EK RQ + +Q K + + K +
Sbjct: 276 RQEEELREQEKKIRKQE--EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR-- 331
Query: 427 QVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRS 486
EQEKE +K ++ + E+ E ++ K E + + R+
Sbjct: 332 -------EQEKELREQKELREQE---------EQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Query: 487 YR--RRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKED 544
R + K ++Q+Q+ + Q+++ + R ++E+ +E+EK E+ E+ E + +E
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE- 434
Query: 545 LLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAEL 604
+EK E E+E + + +K + + + + E N E Q+ E
Sbjct: 435 --QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE----QEEKEW 488
Query: 605 ASMELNESSR--WTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNL 662
L E W +E+M+ ++ + E M G Q K + K R+
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG-----QEKKMWRQEKMREQE 543
Query: 663 DEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAE 722
D++ +Q + ++E+ ++++ E+ E++ E + E++M EE E
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
Query: 723 ALHASGNEVPRGE 735
+ ++ E
Sbjct: 604 MMREQEEKMQEQE 616
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 86.3 bits (212), Expect = 4e-16
Identities = 286/1277 (22%), Positives = 452/1277 (35%), Gaps = 220/1277 (17%)
Query: 59 IQPQRRRPSLLSEFQPGNERSQEL---HLRPESHSYLP----ELGKSEMEFIESKRPRLE 111
+ P+ + LSE P E S ++ L PES L LGK EM +
Sbjct: 1189 VSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSH 1248
Query: 112 LLPDPLLRPSPLLATGQP--------AGSEDLTKDRSLTGKLEPVSPPSP-PHTDPELEL 162
P+ P P AT P + D+T D L+ SP S H+ P
Sbjct: 1249 HTA-PMSVPEPHAATASPPTDGTTRYSAQTDITDD-----SLDRKSPASSFSHSTPS--- 1299
Query: 163 VPPRLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESK 222
N + IT ++ I + +K PE + I K
Sbjct: 1300 -----------GNGKYLPGAITSPDEHILTP-------DSSFSKSPESLPGPALEDIAIK 1341
Query: 223 HRSLVQIIYD---ENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKK 279
V + D E +K+ E +L+ +E +P DT Y ++ +A+ K
Sbjct: 1342 WEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKD----EALHVK 1397
Query: 280 LILYFKRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPE 339
N A KQ ++ Q+ L E+K +E + +A E K ++ EK
Sbjct: 1398 --------NEAVKQQDKALEQKGRDL----EQKDTALEQ--KDKALEPKDKDLEEKD-KA 1442
Query: 340 IRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPML 399
+ ++ ++ E + Q+ + L E + ++ E ++ + Q IP
Sbjct: 1443 LEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDL-------EQKDRVLEQKEKIPEEK 1495
Query: 400 YDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLE 459
A Q+++ + D + KDR + + +K ++ Q K+ E
Sbjct: 1496 DKALDQKVRSVEHKA-PEDTVAEMKDRDL----EQTDKAPEQKHQAQEQKD-----KVSE 1545
Query: 460 RKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEE 519
+K A Y+ L +K+E +Q Q ++ Q Q+Q+ + QE+
Sbjct: 1546 KKDQALEQKYWALGQKDEAL--------------EQNIQALEENHQTQEQESLV---QED 1588
Query: 520 KDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRK 579
K K K E EK EK + +K + L EKT E E++ +GR + +
Sbjct: 1589 KTRKPKMLE-EKSPEKVKAMEEKLEALLEKTKALGLE-----ESLVQEGRAREQEEKYWR 1642
Query: 580 GRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIA- 638
G+ E + + ELA + S + LE W ++
Sbjct: 1643 GQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSC 1702
Query: 639 -RMVG---SKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAAS--- 691
R V + Y ++ LDE E+E R ++P A+
Sbjct: 1703 ERKVWFPHELDGQGARPHYTEERESTFLDEGPDD-----EQEVPLREHATRSPWASDFKD 1757
Query: 692 -EEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNN---SSD 747
+E++ +E E A G E E + L S E+ S P V S+
Sbjct: 1758 FQESSPQKGLEVERWLAESPVGLPPE---EEDKLTRSPFEIISPPASPPEMVGQRVPSAP 1814
Query: 748 TESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPT 807
+ P P + +N P P+ L AD PP P+D P P P P S A G PT
Sbjct: 1815 GQESPIPDPKLMPHM-KNEPTTPSWL-ADIPPW-----VPKDRPLP--PAPLSPAPGPPT 1865
Query: 808 PPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECT 867
P P S P E ++ A E E + L D KAE
Sbjct: 1866 PAP----ESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAE-------G 1914
Query: 868 EEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVD 927
E EEG AEA + + ++ E ATT P+ + +
Sbjct: 1915 EREEEG--------RAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQ 1966
Query: 928 EAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP--LDLKQL---------KQRAAAIPPI 976
A+ ++ L P+ PT +P A+ P L K+ K+ ++ I P
Sbjct: 1967 YADIYEQMMLTGLGPA--CPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPK 2024
Query: 977 VTKVHEPPREDAAPTKP-APPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEK 1035
+ P AA P PP P P +++P P P +P S+ P+PP +
Sbjct: 2025 SLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPI-LSKGPSPPLNGNI-- 2081
Query: 1036 PVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGL 1095
+ ++ P S E+ K + P+ A S +PP HP+P+G
Sbjct: 2082 -----LSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPP-HPIPMG- 2134
Query: 1096 HDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPV 1155
P L P T ++ P + S P+ L P S + + P
Sbjct: 2135 ----SPTL-WPETEAHVSPPLDSHLGPA-------------RPSLDFPASAFGFSSLQPA 2176
Query: 1156 TMGLPLPMDPKKLAP-----FSGVKQEQLSPRGQAGPP------ESLGVPTAQEA-SVLR 1203
LP P +P+ AP FSG + L+P GPP E L V A S L
Sbjct: 2177 PPQLPSPAEPRS-APCGSLAFSGDRALALAP----GPPTRTRHDEYLEVTKAPSLDSSLP 2231
Query: 1204 GTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTP--ADVLYKGTITRIIGEDSPSR 1261
S PG + +P P+ A++ S TP + V + + + E
Sbjct: 2232 QLPSPSSPGAPLLSNLPR---PASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGE 2288
Query: 1262 LDRGREDSLPKGHVIYE 1278
LD G E P H +++
Sbjct: 2289 LDPGME---PAAHSLWD 2302
Score = 51.2 bits (121), Expect = 1e-05
Identities = 143/663 (21%), Positives = 210/663 (31%), Gaps = 118/663 (17%)
Query: 746 SDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGA 805
S E+ +T A K+ + P P +L +D P +P EP P+ E +
Sbjct: 2001 STKEAAAGRNTSAEKEL--SSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLT 2058
Query: 806 P--TPPPAPPSPSAPPPVVPKE--EKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEP 861
P PP AP P P + + + P E G + + ++ G E+P
Sbjct: 2059 PPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQP 2118
Query: 862 VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEG---------GSGRATTAKSSGAP 912
K + G E A + + G S ++ P
Sbjct: 2119 EKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPP 2178
Query: 913 QDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDP-RANASPQKPLDLKQLKQRAA 971
Q + SA A GD+ L+P P T + +P L QL ++
Sbjct: 2179 QLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSS 2238
Query: 972 AIPPIVTKVHEPPR----EDAAPTKPAPPAPPPPQNLQPESDAPQQ------PGSSPRGK 1021
P+++ + P E ++ P + P +A +Q PG P
Sbjct: 2239 PGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAH 2298
Query: 1022 SR------SPAPPADKEAEKPVFFPAFAAEAQKLPGDP-----PCWTS--------GLPF 1062
S SPAPPA + A A LPGD PC PF
Sbjct: 2299 SLWDLTPLSPAPPASLDLA--------LAPAPSLPGDMGDGILPCHLECSEAATEKPSPF 2350
Query: 1063 PVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLP---------------RPP 1107
VP + P P+ PPG P P + P RP
Sbjct: 2351 QVPSEDCAANGPTETSPN-----PPG-PAPAKAENEEAAACPAWERGAWPEGAERSSRPD 2404
Query: 1108 TISNPP----PLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPM 1163
T+ +P P S PS ++ A QG + + E + + + P LP +
Sbjct: 2405 TLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPP---LPPSI 2461
Query: 1164 DPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTR 1223
D + L+ E++ G+ G +G P GT G P +T P T
Sbjct: 2462 DDRDLST------EEVRLVGRGGR-RRVGGP---------GTTGGPCP---VTDETPPTS 2502
Query: 1224 VPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEGKKGH 1283
SDS + S P + E+ PS DS G + K G
Sbjct: 2503 A-SDSGSSQSDS---DVPPET-----------EECPSITAEAALDSDEDGDFLPVDKAGG 2547
Query: 1284 VLSYEG---GMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAISSASIEGLMGR 1340
V G + D R S P A GRV R ++G +GR
Sbjct: 2548 VSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGR 2607
Query: 1341 AIP 1343
P
Sbjct: 2608 RAP 2610
Score = 45.1 bits (105), Expect = 0.001
Identities = 140/624 (22%), Positives = 206/624 (33%), Gaps = 138/624 (22%)
Query: 1534 PVIVPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTTREPTPRLQEGSL---SSSKASQDR 1590
P + P PR +P+ + P G++ SP R P+P+ S S+S + ++
Sbjct: 2055 PSLTPPAVPPR-APILSKGPSPPLNGNILSCSP-DRRSPSPKESGRSHWDDSTSDSELEK 2112
Query: 1591 KLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPL 1650
P + A+SP PHPI L + +H+ D P L
Sbjct: 2113 GAREQPEKEAQSPSP------PHPIPMGSPTLWPET-----EAHVSPPLDSHLGPARPSL 2161
Query: 1651 DAAAAYYLPRHLAPNPTYPHLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHNAATAM 1710
D A+ + L P P P L P R P ++
Sbjct: 2162 DFPASAFGFSSLQPAP--PQLPSPAEPRSAP-------------------------CGSL 2194
Query: 1711 AQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPT 1770
A D L+P + + +++++ P L +P P + L+ LP
Sbjct: 2195 AFSGDRALALAPGPPTRTRHDE-----YLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLP- 2248
Query: 1771 APQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEH 1830
R +S LS G + T P +S +ER
Sbjct: 2249 -------RPASPALSEGSSSEATTPVISSVAER--------------------------- 2274
Query: 1831 APIWRPGTEQSSGSSGSSGGGGGSSSRPASHS--HAHQHSPISPRTQD-ALQQRPSVLHN 1887
+ P E + SG G PA+HS SP P + D AL PS+ +
Sbjct: 2275 ---FSPSLEAAEQESGELDPG----MEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGD 2327
Query: 1888 TGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPK 1947
G GI+ P L S ++ +P+ P+ C G PT P P
Sbjct: 2328 MG-DGIL-------PCHL-ECSEAATEKPSPFQVPSEDCAANG------PTETSP-NPPG 2371
Query: 1948 EAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPV--SGHATIARTP 2005
AP A E A A P G E +S P P V P SG + +P
Sbjct: 2372 PAPAKAENEEAAACPAWERGAWP---EGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASP 2428
Query: 2006 AKNLAPHHASPDP-----PAPPASASDPHREKTQSKPFSIQELEL------RSLGYHGSS 2054
P + +P P+ + P + S +E+ L R +G G++
Sbjct: 2429 EVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTT 2488
Query: 2055 YSP----EGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG---PVKLGGEA 2107
P + P S S S D +P EE E L + G PV G
Sbjct: 2489 GGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGV 2548
Query: 2108 AHLPHLR------PLPESQPSSSP 2125
+ H R PLP+ P SP
Sbjct: 2549 SGTHHPRPGHDPPPLPQPDPRPSP 2572
Score = 44.7 bits (104), Expect = 0.001
Identities = 88/394 (22%), Positives = 134/394 (34%), Gaps = 83/394 (21%)
Query: 743 NNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPT-----PPPEDIPAPTEPT 797
+++SD+E + K+ P PP + P P T PP + P P+
Sbjct: 2103 DSTSDSELEKGAREQPEKEA--QSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPS 2160
Query: 798 ---PASEATGAPTPPPAPP---SPSAP---------------------PPVVPKEEKEEE 830
PAS A G + PAPP SP+ P PP + ++ E
Sbjct: 2161 LDFPAS-AFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLE 2219
Query: 831 TAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEG- 889
AP ++ Q P + A P+ S A ++G +EA
Sbjct: 2220 VTKAPSLDSSLPQLPSPSSPGA--------PLLSNLPRPASPALSEGSSSEATTPVISSV 2271
Query: 890 ------ALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPS 943
+L+A ++E G ++ + D + +D A L+P PS
Sbjct: 2272 AERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLA--------LAPAPS 2323
Query: 944 LLTPTGD-------PRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPP 996
L GD + A+ +KP + + AA P T + P P
Sbjct: 2324 LPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPG-----------P 2372
Query: 997 APPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCW 1056
AP +N + + + G+ P G RS P E+PV PA + G PP
Sbjct: 2373 APAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPV-CPAGGS------GGPPSS 2425
Query: 1057 TSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHP 1090
S P + PH + S PP P
Sbjct: 2426 ASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPP 2459
Score = 42.0 bits (97), Expect = 0.008
Identities = 86/461 (18%), Positives = 171/461 (37%), Gaps = 54/461 (11%)
Query: 475 KNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEE 534
++E K L + + + S++ ++ + ++ + + +++ K K+K + +E+
Sbjct: 349 RSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEK 408
Query: 535 KPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEE 594
++E K+ KEK + +K+ + +K A + +RK +
Sbjct: 409 ISKLEEKKD---KEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLK 465
Query: 595 AITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYF 654
TP+ L ++ + +K L + A V T+S +
Sbjct: 466 PFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVL 525
Query: 655 NYKK--RQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSG 712
+ + Q+ +E+ ++ + + ++R+ K P +EE ++ G+ G
Sbjct: 526 SSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGL-G 584
Query: 713 NEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPAT 772
EE +++E E + EVP + S +++ ++TE KDT + + A
Sbjct: 585 QEEHVMKEKELV----PEVPEEQGSKDRGLDSGAETEE--------EKDTWEEKKQREA- 631
Query: 773 LGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETA 832
E +P TE SE P V+ K E EE
Sbjct: 632 ---------------ERLPDRTEAREESE-------------PEVKEDVIEKAELEEMEE 663
Query: 833 AAPPVEEGEEQKPPAAEELAVDTGKAEEPVK-SECTEEAEEGPAKGKDAEAAEATAEGAL 891
P EE E+ A + +EP+K + + EA G G +A E L
Sbjct: 664 VHPSDEEEED----ATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFL 719
Query: 892 KA-EKKEGGSGRATTAKSSGAPQDSDSSATCSADEV-DEAE 930
+ G + + + P S++ T S +E+ DE E
Sbjct: 720 SSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPE 760
Score = 37.7 bits (86), Expect = 0.14
Identities = 107/511 (20%), Positives = 171/511 (33%), Gaps = 71/511 (13%)
Query: 512 MPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKT 571
+P QEE KEKE E EE+ K++ D+ E +EK+ K ++
Sbjct: 580 VPGLGQEEHVMKEKELVPEVPEEQGS---------KDRGLDSGAETEEEKDTWEEKKQRE 630
Query: 572 ANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLLEHG 631
A R R +E +E + + AEL ME S EE+ A+ +H
Sbjct: 631 AE---RLPDRTEAREESEPEVKEDVI--EKAELEEMEEVHPSDEEEEDATKAEGFYQKH- 684
Query: 632 RNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAAS 691
M V+ F + E+ Q K EKE + PA A+
Sbjct: 685 --------MQEPLKVTPRSREAFGGR------ELGLQGKAP-EKETSLFLSSLTTPAGAT 729
Query: 692 EEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESI 751
E ++ ++DE + +E E E +H E PA + T +
Sbjct: 730 EHVSY---IQDETIPGY----SETEQTISDEEIHDEPEE-------RPAPPRFHTSTYDL 775
Query: 752 PSPHTEAAKDTGQNGPKP-PATLG-ADGPPPGPPTPPPEDIPAP-TEPTPASEATGAPTP 808
P P + Q PAT G G P T P + AP E S AT
Sbjct: 776 PGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITEC 835
Query: 809 PPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTE 868
++ E++ + AP EE L +DT + ++E T+
Sbjct: 836 DKLSSFATSVA-----EDQSVASLTAPQTEE------TGKSSLLLDTVTSIPSSRTEATQ 884
Query: 869 EAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDE 928
+ P+ G + + + K+ E S + K S +E +E
Sbjct: 885 GLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEE 944
Query: 929 AEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDA 988
+ + L + TP +A L + ++R + K+ PP
Sbjct: 945 TANVEMSEKLCSQYG--TPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPP---- 998
Query: 989 APTKPAPPAPPPPQNLQPESDAPQQPGSSPR 1019
P+ PP P +P + S P+
Sbjct: 999 -------PSGPPSATHTPFHQSPVEEKSEPQ 1022
Score = 36.2 bits (82), Expect = 0.42
Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 12/80 (15%)
Query: 729 NEVPRGECSGPATVNNSSD----TESIPSPHTEAAKDTGQNG-----PKPPATLGADGPP 779
+E P S + + SD TE PS EAA D+ ++G K G P
Sbjct: 2496 DETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPR 2555
Query: 780 PG---PPTPPPEDIPAPTEP 796
PG PP P P+ P+P P
Sbjct: 2556 PGHDPPPLPQPDPRPSPPRP 2575
Score = 33.5 bits (75), Expect = 2.7
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 12/76 (15%)
Query: 822 VPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAE 881
V K K EE VEEG ++ A ELA + K E+ K E +E+ P K E
Sbjct: 331 VSKLAKREEV-----VEEGAKE---ARSELAKELAKTEKKAK----ESSEKPPEKPAKPE 378
Query: 882 AAEATAEGALKAEKKE 897
+ + ALKAEK++
Sbjct: 379 RVKTESSEALKAEKRK 394
Score = 32.3 bits (72), Expect = 6.1
Identities = 53/236 (22%), Positives = 81/236 (34%), Gaps = 30/236 (12%)
Query: 824 KEEKEEETAAAPPVEEGEEQKPPAAEELAVDTG----KAEEPVKSECTEEAEEGPAKGKD 879
KE K+E EE+K EE DT K +P T E + K K
Sbjct: 421 KEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKV 480
Query: 880 AEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLS 939
+ A++ EK+ + A+ P + S G + +LS
Sbjct: 481 PGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTIS--------------GHRELVLS 526
Query: 940 PRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIP-PIVTKVHEPPREDAAPTKPAPPAP 998
L T D ++ L +Q P P+ T PP T P+ P
Sbjct: 527 SPEDL---TQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGL 583
Query: 999 PPPQNLQPES----DAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLP 1050
+++ E + P++ GS RG A+ E EK + EA++LP
Sbjct: 584 GQEEHVMKEKELVPEVPEEQGSKDRGLDSG----AETEEEKDTWEEKKQREAERLP 635
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 85.5 bits (210), Expect = 6e-16
Identities = 110/409 (26%), Positives = 146/409 (35%), Gaps = 44/409 (10%)
Query: 712 GNEEEMVEEAEALHASGNEVPRGECSGPATVNN-SSDTESIPSPHTEAAKDTGQNGPKPP 770
G E V A +HA E P +T +S ++P+P + P+ P
Sbjct: 969 GTPEGPVTPATTVHAP--EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEP 1026
Query: 771 ATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP-------PAPPSPSAPPPVVP 823
+ A PPP PT P +P P EPT + A P P P P P++P VP
Sbjct: 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1086
Query: 824 KEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAA 883
E+ AAA P EE PAA AV T EEP E PA A A
Sbjct: 1087 TPEEPTSPAAAVPTP--EEPTSPAA---AVPT--PEEPASPAAAVPTPEEPA--SPAAAV 1137
Query: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPS 943
E A A A+ A + P++S S A + A L S
Sbjct: 1138 PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS 1197
Query: 944 LLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAA----PTKPAPPAPP 999
P A + L++ AA++P E P AA P +P PA
Sbjct: 1198 PAASVPTPAAMVA-----TLEEFTSPAASVP-----TSEEPASLAAAVSNPEEPTSPAAA 1247
Query: 1000 PPQNLQPESDA----PQQPGSSPRGKSRSPAPPADKEAE-KPVFFPAFAAEAQKLPGDPP 1054
P +P S A + SSP +P PA A + PA A A P
Sbjct: 1248 VPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE--- 1304
Query: 1055 CWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHP-LPLGLHDTARPV 1102
+ +P P + A P A P +P G P L + H + P+
Sbjct: 1305 --VAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPI 1351
Score = 77.8 bits (190), Expect = 1e-13
Identities = 108/451 (23%), Positives = 158/451 (35%), Gaps = 44/451 (9%)
Query: 686 APAAASEEAAFPPV---VEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRG-ECSGPAT 741
A +A E A P V V + + VS EE A A+ G G A
Sbjct: 899 AAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAAL 958
Query: 742 VNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASE 801
TE +P T + P+ P T P P P +P P EPT S
Sbjct: 959 AITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPT--SP 1016
Query: 802 ATGAPTP-PPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEE 860
A PTP P P+ + PPP EE T+ A V EE PAA AV T EE
Sbjct: 1017 AAAVPTPEEPTSPAAAVPPP-------EEPTSPAAAVPTPEEPTSPAA---AVPT--PEE 1064
Query: 861 PVKSECTEEAEEGPAKGKDA--EAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSS 918
P E P A E T+ A +E T+ ++ P + +
Sbjct: 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE------PTSPAAAVPTPEEPA 1118
Query: 919 ATCSADEVDEAEGGDKNRLLSPR----PSLLTPTGDPRANASPQKPLDLKQLKQRAAAIP 974
+ +A E + +P P+ PT + A+A+ P ++ AAA+P
Sbjct: 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTP-EESASPAAAVP 1177
Query: 975 ---------PIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAP--QQPGSSPRGKSR 1023
+V + EP A+ PA + P + P ++P S S
Sbjct: 1178 TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN 1237
Query: 1024 SPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFS 1083
P + A + P +A A P + + +P P P A + +P++ +
Sbjct: 1238 PEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPA 1297
Query: 1084 YA-PPGHPLPLGLHDTARPVLPRPPTISNPP 1113
A P + P +P P + PP
Sbjct: 1298 AAVPTPEVAAIPAASVPTPEVPAIPAAAVPP 1328
Score = 61.6 bits (148), Expect = 9e-09
Identities = 127/535 (23%), Positives = 175/535 (32%), Gaps = 104/535 (19%)
Query: 790 IPAPTEPT-----PASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQK 844
+P+P E T PA E T P + E+E+ TAAA V E
Sbjct: 851 LPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAA--VSAPERAT 908
Query: 845 PPAAEELAVDTGKAEEPVKSECTEEAEEGPA----KGKDAEAAEATAEGALK-----AEK 895
PA ++V G A S E A A +G A A + AL E+
Sbjct: 909 VPAVT-VSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEE 967
Query: 896 KEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANA 955
G T A + AP++ D++A V E P P PT A
Sbjct: 968 DGTPEGPVTPATTVHAPEEPDTAAV----RVSTPEEPASPAAAVPTPE--EPTSPAAAVP 1021
Query: 956 SPQKPLDLKQLKQRAAAIPP---------IVTKVHEPPREDAA------PTKPAPPAPPP 1000
+P++P AAA+PP V EP AA PT PA P P
Sbjct: 1022 TPEEPTS------PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1075
Query: 1001 PQNLQPES--DAPQQPGSSPRGKSRSPAPPADKEAEKPV-FFPAFAAEAQKLPGDPPCWT 1057
+ P + P++P +SP +P P A P PA A A P +P
Sbjct: 1076 EEPTSPAAAVPTPEEP-TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPA 1134
Query: 1058 SGLP------FPVP----PREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVL---- 1103
+ +P FP P P E A+ P P + P P A V
Sbjct: 1135 AAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194
Query: 1104 PRPPTISNPPPL---------------ISSAKHPSVLERQIGAISQGMSVQLHVPYSEHA 1148
P P S P P + +++ P+ L + + S VP E
Sbjct: 1195 PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254
Query: 1149 KAPVGPV---------TMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA 1199
+ V +P P +P A +E SP PE +P A
Sbjct: 1255 TSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA--- 1311
Query: 1200 SVLRGTALGSVPGGSITKGIPSTRVP-----SDSAITYRGSITHGTPADVLYKGT 1249
SVP + IP+ VP S + + G H + +GT
Sbjct: 1312 ---------SVPTPEV-PAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGT 1356
Score = 57.0 bits (136), Expect = 2e-07
Identities = 95/426 (22%), Positives = 138/426 (32%), Gaps = 59/426 (13%)
Query: 813 PSPSAPPPVVPKEEKEEETAAAPPVEEGEE-QKPPAAEELAVDTGKAEEPVKSECTEEAE 871
PS +A P V K+ AA P EEG PA E AV P +
Sbjct: 834 PSRTAAVPTV----KDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIV 889
Query: 872 EGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEG 931
+ A A A + A G A A S + + + A E A
Sbjct: 890 SLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVA 949
Query: 932 GDKNRLLSPRPSLLTPTGD-PRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAA- 989
G SP + L T + +P+ P + P T VH P D A
Sbjct: 950 G-----FSPEWAALAITVPITEEDGTPEGP------------VTPATT-VHAPEEPDTAA 991
Query: 990 -----PTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAA 1044
P +PA PA P +P S A P + PP ++ P A
Sbjct: 992 VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEE--------PTSPA 1043
Query: 1045 EAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLP 1104
A P +P + +P P P A P +P++ + A P P + +P
Sbjct: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT----SPAAAVP 1099
Query: 1105 RPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMD 1164
P ++P + + + P+ S VP E +P V P P +
Sbjct: 1100 TPEEPTSPAAAVPTPEEPA-------------SPAAAVPTPEEPASPAAAV----PTPEE 1142
Query: 1165 PKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRV 1224
P AP +E S PE P A + + +V P+ V
Sbjct: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASV 1202
Query: 1225 PSDSAI 1230
P+ +A+
Sbjct: 1203 PTPAAM 1208
Score = 36.6 bits (83), Expect = 0.32
Identities = 77/366 (21%), Positives = 113/366 (30%), Gaps = 70/366 (19%)
Query: 1898 EPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPER 1957
EP T V R ++ P PAA P T EP P P
Sbjct: 986 EPDTAAV-RVSTPEEPASPAAAVP----------------TPEEPTSPAAAVPTPEEPTS 1028
Query: 1958 PRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPD 2017
P A A PP PA++ EP + A TP + +P A P
Sbjct: 1029 PAA-------AVPPPEEPTSPAAAVPTPEEP-------TSPAAAVPTPEEPTSPAAAVPT 1074
Query: 2018 PPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGL 2077
P P + A+ + + P + + +PE EP SP ++ +
Sbjct: 1075 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE--EPASPAAAVPTPEEPAS 1132
Query: 2078 PKHLEELDKSHLEGELRPKQPGP-VKLGGEAAHLPHLRPLPESQPSSSPLLQT------- 2129
P + + P P P V E+A P PE S + + T
Sbjct: 1133 P-------AAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASF 1185
Query: 2130 -------------APGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLY-SFPG 2175
A V +V + + T P L+A + P + P
Sbjct: 1186 AAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPA 1245
Query: 2176 ASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPP 2235
A+ P L+ + L P + +PA P E EP + + EP SP
Sbjct: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPE------EPASPAAAVSNLE--EPASPA 1297
Query: 2236 EGMTEP 2241
+ P
Sbjct: 1298 AAVPTP 1303
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 84.3 bits (207), Expect = 1e-15
Identities = 134/527 (25%), Positives = 186/527 (35%), Gaps = 88/527 (16%)
Query: 745 SSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPG---PPT---------------PP 786
S T+S P+P AA Q PP+ + P G P T P
Sbjct: 565 SLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPA 624
Query: 787 PEDIPAPTEPTPAS-EATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKP 845
P+ PA + P P + A PP AP +A PP + A++P E+ +P
Sbjct: 625 PQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSP--EKIVLGQP 682
Query: 846 PAAEELAVDTG----------------KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEG 889
P+A A+ T AE P S P +D A A+G
Sbjct: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
Query: 890 A-LKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL--LT 946
A L + + + A + A + S +A GD L SP P+
Sbjct: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802
Query: 947 PTGDPRANASP--QKPLDLKQLKQRAAAIPPIVTKVHE----PPREDAAPTKPAPPAPP- 999
P P++ + P + PL Q +P I ++ PP + APT P PP PP
Sbjct: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPL 862
Query: 1000 PPQNLQPESDAPQQP-----------GSSPRGKSRSPAP-PADKEAEKPVFFPAFAAEAQ 1047
PQ+ PE P P SS SR PAP P+D + + P +
Sbjct: 863 RPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPP-----SQGPH 917
Query: 1048 KLPGDPPCW----TSGLPFPVPPRE---VIKASPHAPDPSAFSYAPPGHPLPLG--LHDT 1098
K P PP P P PPR V P P P A H +P G L +
Sbjct: 918 KSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKAL--LERFHQVPSGIILQNK 975
Query: 1099 ARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMG 1158
A P T ++ PL S A + G + HA AP G
Sbjct: 976 AGGAPAAPQTSTSLGPLTSPA---------ASVLVSGQAPSGTPTAPSHAPAPAPMAATG 1026
Query: 1159 LP--LPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLR 1203
LP LP + K A S + ++ +GP + G+ + S L+
Sbjct: 1027 LPPLLPAENKAFA--SNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071
Score = 63.5 bits (153), Expect = 2e-09
Identities = 105/457 (22%), Positives = 157/457 (34%), Gaps = 56/457 (12%)
Query: 684 KKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVN 743
++ P A + +AA PP + + G++ + E++V + +
Sbjct: 645 QQPPQAPTPQAAAPPQATTPQ-PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQE 703
Query: 744 NSSDTESIPSPHTEAAKDTGQNGPKP-----PATLGADGPPPGPPTPPPEDIPAPTEPTP 798
S S PH + P P PAT A G GP P + PAP P
Sbjct: 704 RSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIP 763
Query: 799 ASEATGAPTPPPAPPSPSAPP----PVVPKEEKEEETAAAPPVEEGEEQKPPAAEEL-AV 853
A+ P P +P P P P +P + PP +PP+ L
Sbjct: 764 AAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPH-PTRPPSRPPSRPQSVSRPPSEPPLHPC 822
Query: 854 DTGKAEEPVKSECTEEAEEG--PAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGA 911
+A + + + G P A A + L+ + + +
Sbjct: 823 PPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ---PPEGPLPPAPHL 879
Query: 912 PQDSDSSATCSADEVDEAEGGDKNRLLSPRPS----LLTPTGDPRANASPQKPLDLKQLK 967
P S SSA S+ E +RL +P PS P+ P + SP P L +
Sbjct: 880 PPSSTSSAVASSSET-------SSRLPAPTPSDFQLQFPPSQGP--HKSPTPPPTLHLVP 930
Query: 968 QRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAP------QQPGSSPR-- 1019
+ AA PP PPR T P P P P L+ P + G +P
Sbjct: 931 EPAAPPPP-------PPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
Query: 1020 ------GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKAS 1073
G SPA + P P + A P P +GLP P+ P E +
Sbjct: 984 QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHA---PAPAPMAATGLP-PLLPAENKAFA 1039
Query: 1074 PHAPDPSAFSYAPPGHPLPLGL-HDTARPVLPRPPTI 1109
+ P + A G P GL +++ L +PPT+
Sbjct: 1040 SNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTL 1076
Score = 51.6 bits (122), Expect = 1e-05
Identities = 52/177 (29%), Positives = 66/177 (37%), Gaps = 29/177 (16%)
Query: 759 AKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAP---PSP 815
A D P PPATL PPP PP PPP PT T PP AP P
Sbjct: 1326 ALDPVHQPPPPPATLKVAEPPPRPPPPPP--------PTGQMNGTVDHPPPAAPERKPLG 1377
Query: 816 SAPP-PVVPKEEKEEETAAAPPVEEG----------EEQKPPAAEELAVDTGKAEEPVKS 864
+AP P +P + E P EG P +E + V+
Sbjct: 1378 TAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVED 1437
Query: 865 ECTEEAEEGPAKGKDAEAAEAT------AEGALKAEKKEGGSGRATTAK-SSGAPQD 914
E + +GP A AA+ T A G A++++ S A SS +PQD
Sbjct: 1438 ELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQD 1494
Score = 44.7 bits (104), Expect = 0.001
Identities = 78/329 (23%), Positives = 108/329 (32%), Gaps = 66/329 (20%)
Query: 1721 SPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHS 1780
+P + A A P+ L+ P VL P TP + + + PQ S
Sbjct: 650 APTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQ----ERS 705
Query: 1781 SSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQ 1840
PLS GP HL+ P S++ S P P T
Sbjct: 706 QQPLSAEGP-HLSVPA-----------------------SVIVSAPPPAQDPA--PATPV 739
Query: 1841 SSGSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNT--GMKGIITAVE 1898
+ G+ G G + AS + A Q +P PS+ H G + +
Sbjct: 740 AKGA----GLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPH 795
Query: 1899 PSTPTVLRSTSTSSPVRPAATFPPATHCP---LGGTLDGVY----------------PTL 1939
P+ P + S RP + PP CP TL G++ PT
Sbjct: 796 PTRPPSRPPSRPQSVSRPPSE-PPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTA 854
Query: 1940 -------MEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLV 1992
+ P P E P P P + T A + S L PA +PS P
Sbjct: 855 PGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRL-PAPTPSDFQLQFP-- 911
Query: 1993 PPVSGHATIARTPAKNLAPHHASPDPPAP 2021
P H + P +L P A+P PP P
Sbjct: 912 PSQGPHKSPTPPPTLHLVPEPAAPPPPPP 940
Score = 42.0 bits (97), Expect = 0.008
Identities = 41/139 (29%), Positives = 57/139 (41%), Gaps = 21/139 (15%)
Query: 898 GGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASP 957
GGS T A++S + S SS++ +A +D E G P PS P P
Sbjct: 1254 GGSPSVTWARASSSLSSSSSSSS-AASSLDADEDG-------PMPSRNRP---PIKTYEA 1302
Query: 958 QKPLDLKQLKQRAAAIPPIVTK-----VHEPPREDA----APTKPAPPAPPPPQNLQPES 1008
+ + LK ++ A + +V VH+PP A A P PP PPPP Q
Sbjct: 1303 RSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPP-PPPPPTGQMNG 1361
Query: 1009 DAPQQPGSSPRGKSRSPAP 1027
P ++P K AP
Sbjct: 1362 TVDHPPPAAPERKPLGTAP 1380
Score = 37.0 bits (84), Expect = 0.25
Identities = 86/371 (23%), Positives = 117/371 (31%), Gaps = 123/371 (33%)
Query: 1897 VEPSTPTVLRSTSTSSPV---RPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVA 1953
V+P+TP +T ++PV +PA PPA PL L P +P P P+ A
Sbjct: 603 VQPATPAA--ATGEAAPVLTVQPAPQAPPAVSTPLPLGLQ--QPQAQQPPQAP--TPQAA 656
Query: 1954 RPER---PRADTGHA------FLAKPPARSGLE--------------------------- 1977
P + P+ G A L +PP+ +
Sbjct: 657 APPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
Query: 1978 --PAS----SPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHRE 2031
PAS +P +P P P G + P +P PAP A+ P
Sbjct: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASP------APAPQIPAAAP--- 767
Query: 2032 KTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEG 2091
++ P SSPSL H L D HL
Sbjct: 768 ----------------------------LKGPGPSSSPSLPHQAPLG------DSPHLPS 793
Query: 2092 ELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVIT 2151
+ P P RP S+P S P L P + + + +
Sbjct: 794 PHPTRPPS----------RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGI------FVI 837
Query: 2152 QDYTRHHPQQLSAPLPA--PLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGS----P 2205
Q+ QL P PA P + PG P L + P + LPP H P+ S
Sbjct: 838 QN-------QLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVAS 890
Query: 2206 HSEGGKRSPEP 2216
SE R P P
Sbjct: 891 SSETSSRLPAP 901
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 82.8 bits (203), Expect = 4e-15
Identities = 113/468 (24%), Positives = 157/468 (33%), Gaps = 66/468 (14%)
Query: 753 SPHTEAAKDTGQNGPKPPATLGAD-----GPPPGPPTPPPEDIPAPTEPTPASEATGAPT 807
+P T+ AK Q P T AD P P+P I PT P ++ G
Sbjct: 264 TPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK 323
Query: 808 PPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECT 867
P P P A P + K ++ PPV+ KPPA + P K
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA---------QPLGPAKPPAQ 374
Query: 868 EEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVD 927
+ E P+ + A A G K ++ G + T + G P+ +
Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT-QQVGTPKPLAQQPGLQSPA-- 431
Query: 928 EAEGGDKNRLLSPRPSLLT---------------PTGDPRANASPQKPLDLKQLKQRAAA 972
+A G K + P P + PT P P KP + A
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP---PPQQPGPAK 488
Query: 973 IPPIVTKVHEPPREDAAPTKPAP--PAPPPPQNLQPESDAP--QQPGSS-PRGKSRSPAP 1027
PP +PP + TKP P P P P QP S P QQPGS+ P + SPA
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
Query: 1028 PADKEAEKPVFFPAFAAEAQKLPGDPPCW---TSGLPFPVPPR-EVIKASPHAPDPSAFS 1083
P+ +++ KPV Q P + GLP + P + H P+ + F+
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 1084 YAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVP 1143
L NP P ++ K L Q+ G VP
Sbjct: 609 TCTECQTTVCSLCG------------FNPNPHLTEVKEWLCLNCQMKRALGGDLAP--VP 654
Query: 1144 YSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESL 1191
S K PVT S + +Q SP+ A P + L
Sbjct: 655 SSPQPKLKTAPVT--------TTSAVSKSSPQPQQTSPKKDAAPKQDL 694
Score = 62.0 bits (149), Expect = 7e-09
Identities = 123/535 (22%), Positives = 184/535 (34%), Gaps = 98/535 (18%)
Query: 668 QHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHAS 727
Q L + + R ++K P + + +++ S + E AL A
Sbjct: 107 QPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAV 166
Query: 728 GNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGP----KPPATLGADGPPPGPP 783
+ V + P + + S+ + + Q P KPP L P P P
Sbjct: 167 SSVVNK---FNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPP--LQQQPPKPIPK 221
Query: 784 TPPPEDIPAPTEPTPASEATGAP----TPPPAPPSPSAPPPVVPKEEKE----EETAAAP 835
P P + TP S ++ P + PP P P P+ + + A+ P
Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
Query: 836 PVEE-----GEEQKP----PAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEAT 886
++ GE KP P+ + T + P + E+++ GPAK A
Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGHEKSQPGPAK------PPAQ 334
Query: 887 AEGALKAEKKEGGSGR------ATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSP 940
G K ++ G+ + TT + + A + E +E L P
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394
Query: 941 RPSLLTPTGDPRANASPQK----PLDLKQ---LKQRAAAIPPIVTKVHEP-----PREDA 988
TP P P + P L Q L+ A A P T V +P P + A
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 989 ----------APTKPAP----PAPPPPQNLQPESDAPQQPGSS--PRGKSRSPAPPADKE 1032
PTKP PA PPPQ P PQQPGS+ P + S PP +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ- 513
Query: 1033 AEKPVFFPAFAAEAQKLPGD--PPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHP 1090
P A + + PG PP G A P A PS +
Sbjct: 514 -------PGPAKPSPQQPGSTKPPSQQPG-----------SAKPSAQQPSPAKPSAQQST 555
Query: 1091 LPLGLHDTARPVLPRPPTISNPPPLISSAKHP--SVLERQIGAISQGMSVQLHVP 1143
P+ + +P+ +PPT+S SAK P L + I + + LHVP
Sbjct: 556 KPVSQTGSGKPL--QPPTVS------PSAKQPPSQGLPKTICPLCNTTELLLHVP 602
Score = 58.9 bits (141), Expect = 6e-08
Identities = 112/499 (22%), Positives = 180/499 (36%), Gaps = 66/499 (13%)
Query: 674 EKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEA-LHASGNEVP 732
EK + K P+ ++ A P ++ G + + + A+ +G+E P
Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 733 RGECSGPATVNNSSDTESIPSPHTEAAKDTGQN--GPKPPATL-GADGPPPGP-PTPPPE 788
E GP + P+ AK Q PKP A G P P PT P
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 789 DIPAPTEPTPASEA---------TGAPTPP---PAPPSPSAPPPVVPKEEKEEETAAAPP 836
P P + PA +A TG PP P P P P K ++ +A PP
Sbjct: 442 QQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 837 VEEGEEQKPPAAEELAVDTGKAE-EPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEK 895
++ KPP + G A+ P + T+ + P K + + A+ + +
Sbjct: 501 SQQPGSTKPPPQQ-----PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 896 K---EGGSGR----ATTAKSSGAPQDSDSSAT----CSADE--VDEAEGGDKNRLLSPRP 942
K + GSG+ T + S+ P T C+ E + E + N +
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615
Query: 943 SLLTPTG-DPRANASPQKP---LDLKQLKQRAAAIPPIVTKVHEPPREDAAP---TKPAP 995
++ + G +P + + K L+ + + + P+ + P+ AP T
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS--PQPKLKTAPVTTTSAVS 673
Query: 996 PAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPC 1055
+ P PQ P+ DA + S + + P PP K+ P + +A+A++ P
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKP-PPLVKQ---PTLHGSPSAKAKQPPE---- 725
Query: 1056 WTSGLPFPVPPREVIKAS-----PHAPD-PSAFSYAPPGHPLPLGLHDTARPVLPRPPTI 1109
L P PP+E S P A D P P L T +P +P
Sbjct: 726 -ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 1110 S-----NPPPLISSAKHPS 1123
S PPL + + PS
Sbjct: 785 SQAEEKTTPPLKTDSAKPS 803
Score = 58.5 bits (140), Expect = 8e-08
Identities = 92/437 (21%), Positives = 149/437 (34%), Gaps = 48/437 (10%)
Query: 752 PSPHTEAAKDTGQNGPKPPATLGAD-GPPPGPPTPPPEDIPAPT-----EPTPASEATGA 805
P+PH K+ + LG D P P P P + P T + +P + T +
Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT-S 683
Query: 806 PTPPPAP-------PSPSAPPPVV--PKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTG 856
P AP P P PPP+V P A P E KP +E +V +
Sbjct: 684 PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE 743
Query: 857 KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSD 916
+ + PV + ++ + ++ AT + + + K + + TT P +D
Sbjct: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-----PLKTD 798
Query: 917 SSATCSADEVDEAEGGDKNRLLSPRP---SLLTPTGDPRANASPQKPLDLKQLKQRAAAI 973
S+ + + + PRP S + P + + QK +D Q K+
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE---- 854
Query: 974 PPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEA 1033
P + P+ DA P P PP P+ ++ Q P+ +SR +
Sbjct: 855 -PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
Query: 1034 EKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKAS---PHAPDPSAFSYAPPGHP 1090
+ P + P P +G F +AS A P S + PG P
Sbjct: 914 DAP----------KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
Query: 1091 LPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKA 1150
+ P +PPT PP A + ++ + + P +E A
Sbjct: 964 M------KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT 1017
Query: 1151 PVGPVTMGLPLPMDPKK 1167
T P P+ K
Sbjct: 1018 VKRTETEKKPPPIKDSK 1034
Score = 54.7 bits (130), Expect = 1e-06
Identities = 114/547 (20%), Positives = 177/547 (32%), Gaps = 75/547 (13%)
Query: 1741 LSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTH--LTKPTTT 1798
+S+ LP P + +M R L ++ P + S P PG P L+K TT
Sbjct: 60 MSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPP---KQSGRPPDPGRPAQPGLSKSRTT 116
Query: 1799 SSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPG--TEQSSGSSGSSGGGGGSSS 1856
+ E+ ++S + EH PG +E ++ S+ SS +
Sbjct: 117 DTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPF 176
Query: 1857 RPASHSHAHQHSPISPRT-------------QDALQQRPS--VLHNTG-------MKGII 1894
S S A Q + + LQQ+P + G G
Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP 236
Query: 1895 TAVEPSTPTVLRST--STSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV 1952
++ P ++S T P++ P H L D P + ++ E+ +
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
Query: 1953 ARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPH 2012
+ P + KPPA+ +P S+ +P P +A+ P P
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQ---QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 2013 H--ASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPS 2070
+ PPA P + P ++T S+ S ++ ++L +P P P
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP-GPAKPP- 411
Query: 2071 LTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTA 2130
T G PK L + +P P K G P P+ + P P Q
Sbjct: 412 -TQQVGTPKPLAQ----------QPGLQSPAKAPG-----PTKTPVQQPGPGKIPAQQAG 455
Query: 2131 PGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDL---RRPP 2187
PG Q Q P QL P P PG + P +PP
Sbjct: 456 PGKTSAQ--------------QTGPTKPPSQLPGPAKPPPQQ-PGPAKPPPQQPGSAKPP 500
Query: 2188 SDL---YLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHS 2244
S PPP PA+ SP G + P S + + T+P
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Query: 2245 RSAVYPL 2251
+ PL
Sbjct: 561 TGSGKPL 567
Score = 49.7 bits (117), Expect = 4e-05
Identities = 95/390 (24%), Positives = 139/390 (35%), Gaps = 79/390 (20%)
Query: 857 KAEEPVKSECTEE---AEEGPAKGKDAEAAEATAEGALKA--EKKEGGSGRATTAKSSGA 911
K E PV + + +E+ P K E L+A +KKE + R ++ S
Sbjct: 2280 KPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETV 2339
Query: 912 PQDSDSS--ATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQR 969
SS A +++ +P+ P+G P ++ P KP +
Sbjct: 2340 FDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSL 2399
Query: 970 AAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR-----GKSRS 1024
+ P PP P PP PPPP P P P +SP+ K +
Sbjct: 2400 DISAQP-------PP--------PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT 2444
Query: 1025 PAPPADKEAEKPVFFPAFAAE------AQKLPGDPPCWTSGLPFPVPPREVIKASPHAPD 1078
A P P+F E + LP C T+ P PVPP+
Sbjct: 2445 VASPV--TTATPLFDAVTTLETTAVLRSNGLPVTRICTTA--PPPVPPK----------- 2489
Query: 1079 PSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNP--PPLISSAKHPSVLERQIGAISQGM 1136
PS+ +P GL T RP +PP P P L ++ + P+ + + +S
Sbjct: 2490 PSS---------IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540
Query: 1137 SVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPR-----GQAGPPESL 1191
S+ L++ S K LP P P L+P S + S P
Sbjct: 2541 SMTLNLVTSADYK---------LPSPTSP--LSPHSNKSSPRFSKSLTETYVVITLPSEP 2589
Query: 1192 GVPTAQEASVLRGTALGSVPGGSITKGIPS 1221
G PT AS A+ S P GS +K + S
Sbjct: 2590 GTPTDSSAS----QAITSWPLGSPSKDLVS 2615
Score = 46.2 bits (108), Expect = 4e-04
Identities = 25/66 (37%), Positives = 29/66 (43%), Gaps = 21/66 (31%)
Query: 773 LGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKE---EKEE 829
+ A PPP PP PPP P PPP PP P PPP PK K++
Sbjct: 2401 ISAQPPPPPPPPPPP------------------PPPPPPPPPPPLPPPTSPKPTILPKKK 2442
Query: 830 ETAAAP 835
T A+P
Sbjct: 2443 LTVASP 2448
Score = 45.8 bits (107), Expect = 5e-04
Identities = 85/467 (18%), Positives = 182/467 (38%), Gaps = 64/467 (13%)
Query: 183 ITMVEQQISKLKKKQQQLEEEAAKPPE--PEKPVSPPPIESKHRSLVQIIYDENRKKAEA 240
++++E Q S L ++ E+ +P E PE+P +S +L I +E K+++
Sbjct: 1417 LSILEAQASTLADEKS---EKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQE 1473
Query: 241 AHRILEGLGPQVELP----------LYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHA 290
+ Q ++P + + R+ +++++ + + KRR
Sbjct: 1474 ERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSV 1533
Query: 291 RKQWEQKFCQRYDQLMEAWEKKVER--IENNPRRRAKESKVREYYEKQFPEIRKQRELQE 348
++ Q Q E + + IE + A S+ E+ Q EI E Q+
Sbjct: 1534 GSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQK 1593
Query: 349 RMQSR-------------VGQRGSGLSMSAAR------SEHEVSEIIDGLSEQENLEKQM 389
+ +++ + + + A R + E + L +E ++
Sbjct: 1594 KEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQES 1653
Query: 390 RQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHP- 448
+L V +R K I +N +AD ++ +++ ++E E E P
Sbjct: 1654 EELVVTG----GGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPE 1709
Query: 449 -KNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQ 507
++ G +S L + ++ +E+ S K + +QQ++ + +
Sbjct: 1710 DRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHK-----KGESKQQRKARHRPHG 1764
Query: 508 QQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASK 567
P S EE++ +E+E+ +++E++ E+E + ++ + S +D DE A
Sbjct: 1765 PLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQ----RKSSSKKSKKDKDELRA---- 1816
Query: 568 GRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASM-ELNESS 613
RR+ R +N + E+A ++ + A M EL+ SS
Sbjct: 1817 --------QRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855
Score = 44.3 bits (103), Expect = 0.002
Identities = 51/240 (21%), Positives = 92/240 (38%), Gaps = 28/240 (11%)
Query: 809 PPAPPSPSAPPPVVPKEEKEEETAAAPP---VEEGEEQKPPAAEELAVDTGK---AEEPV 862
PPAP P A P VP E ++TA P V++ E++ AE++ ++ K + E +
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKI 1185
Query: 863 KSECTEEAEEGPAKGKDAEAAEATAEGALKAEKK--------EGGSGRATTAKSSGAPQD 914
T + ++ +K + +A+ + L EKK + + P+D
Sbjct: 1186 PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPED 1245
Query: 915 SDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIP 974
+E K+ LL + + + R +P+ + KQ + + +P
Sbjct: 1246 KKLLPEAKTSAPEE----QKHDLLKSQVQIAEEKLEGR--VAPKTVQEGKQPQTKMEGLP 1299
Query: 975 PIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAP------QQPGSSPRGKSRSPAPP 1028
+ P+ED TK P PP +P+ P ++ S S+ P P
Sbjct: 1300 SGTPQ--SLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Score = 42.7 bits (99), Expect = 0.004
Identities = 41/179 (22%), Positives = 58/179 (32%), Gaps = 41/179 (22%)
Query: 679 ARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSG 738
A R KK+ A ++ + V + + E+ + G E P +
Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPS 2378
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTP 798
+ +S + P + + + Q P PP PPP PP PPP +P PT P P
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP---PPPPPPPPPPPPPPLPPPTSPKP 2435
Query: 799 ----------ASEATGA----------------------------PTPPPAPPSPSAPP 819
AS T A PPP PP PS+ P
Sbjct: 2436 TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIP 2494
Score = 42.0 bits (97), Expect = 0.008
Identities = 107/498 (21%), Positives = 161/498 (32%), Gaps = 106/498 (21%)
Query: 787 PEDIPAPTEPTPASEATGAPTPPPAP----------------------------PSPSAP 818
PE + A + G+P+ P P S P
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP 72
Query: 819 PPVVPK---EEKEEETAAAPPVEEGEEQKP--PAAEELA----VDTGKAEE--PVKSECT 867
P K+E ++ PP + G P PA L+ DT ++E+ P +S T
Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132
Query: 868 EEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSA----TCSA 923
+E ++ E +++ +E + + K + SDS A T
Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192
Query: 924 DEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLD--------LKQLKQRAAAIPP 975
+V + E G ++ P P P+ + PL Q ++ + PP
Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252
Query: 976 IVTKVHEPP--------------REDAAP------------TKPAPPAP--PPPQNLQPE 1007
K + P R+ + P KP+ P+P PP Q P
Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312
Query: 1008 SDAPQQPG--SSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPV- 1064
QQPG S G ++ PA P+ KP+ A K P PP T P+
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSG--LTKPL---AQQPGTVKPPVQPPGTTKPPAQPLG 367
Query: 1065 ---PPREVI---KASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT--------IS 1110
PP + K S P P A + PPG +G +P +PPT ++
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALA-QPPG----VGKTPAQQPGPAKPPTQQVGTPKPLA 422
Query: 1111 NPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAP 1170
P L S AK P + + G + + GP LP K
Sbjct: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 1171 FSGVKQEQLSPRGQAGPP 1188
G + G A PP
Sbjct: 483 QPGPAKPPPQQPGSAKPP 500
Score = 41.2 bits (95), Expect = 0.013
Identities = 61/299 (20%), Positives = 96/299 (32%), Gaps = 18/299 (6%)
Query: 741 TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTE----P 796
T + S + + P ++K Q K L D P PP + +P + P
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 797 TPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTG 856
PAS++ P P+ S V P ++KEE A + + KP T
Sbjct: 823 RPASDSKIISHPGPSSES-KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS---PTP 878
Query: 857 KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRAT-TAKSSGA---- 911
P + ++ P + + A K + + + T T K G
Sbjct: 879 PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI 938
Query: 912 -PQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRA 970
Q S+ +T G +P PS + P + P K + +
Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKK 998
Query: 971 AAIPPIVTKVHEPPREDAAPT--KPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAP 1027
P K+ P+ + APT + PPP A Q P +SP P
Sbjct: 999 ETKAPAAEKLE--PKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKP 1055
Score = 40.8 bits (94), Expect = 0.017
Identities = 79/369 (21%), Positives = 131/369 (35%), Gaps = 56/369 (15%)
Query: 509 QQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKED---LLKEKTDDTSGEDNDEKEAVA 565
+QP P + K KE E++K V +DK ++K TD S K +
Sbjct: 721 KQP-PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP 779
Query: 566 SKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKK 625
S ++ +EE TP + S + ++S T E++
Sbjct: 780 SS-------------------KVQSQAEEKTTPPLKTD--SAKPSQSFPPTGEKVSPFDS 818
Query: 626 GLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKK 685
+ + S I G + S K ++ +D + ++ + K + + + + K
Sbjct: 819 KAIPRPASDSKIISHPGPSSES---------KGQKQVDPVQKKEEPKKAQTKMSPKPDAK 869
Query: 686 APAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPA-TVNN 744
S P + + S +E S + P+ + + P TV
Sbjct: 870 PMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG 929
Query: 745 S--SDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEA 802
SI S + GQ GP + GA P + PAP++P P S+
Sbjct: 930 KLFGFGASIFSQASNLISTAGQPGPHSQSGPGA----------PMKQAPAPSQP-PTSQG 978
Query: 803 TGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPV 862
T APP+P+ PV +KE + AA +E EQ P +T K P+
Sbjct: 979 PPKSTGQ-APPAPAKSIPV----KKETKAPAAEKLEPKAEQAPTVKR---TETEKKPPPI 1030
Query: 863 KSECTEEAE 871
K + AE
Sbjct: 1031 KDSKSLTAE 1039
Score = 40.4 bits (93), Expect = 0.022
Identities = 49/218 (22%), Positives = 84/218 (38%), Gaps = 29/218 (13%)
Query: 667 QQHKLKMEKER-NARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALH 725
+Q + K+EK++ +A ++KK P EE P E+E++ S ++ ++EE +
Sbjct: 1194 KQEESKLEKDKASALQEKKPLP----EEKKLIP--EEEKIR----SEEKKPLLEEKKPTP 1243
Query: 726 ASGNEVPRGECSGPATVNNSSDTESIPSPHTE----AAKDTGQNGPKPPATLGADGPPPG 781
+P + S P + + + A T Q G +P + G
Sbjct: 1244 EDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKM------EG 1297
Query: 782 PPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGE 841
P+ P+ +P + T T P PP + P V P +EK E+ +
Sbjct: 1298 LPSGTPQSLPKEDDKT-----TKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQ 1352
Query: 842 EQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKD 879
+ K P DTG + + + S E P KD
Sbjct: 1353 QPKSPQG---LSDTGYSSDGISSSLGEIPSLIPTDEKD 1387
Score = 38.9 bits (89), Expect = 0.065
Identities = 55/245 (22%), Positives = 96/245 (39%), Gaps = 40/245 (16%)
Query: 1396 PSRDLTEAYKTQALGPLKLKPAHEGLVATV-----------KEAGRSIHEIPREELR--- 1441
P +DL++A + + PL +P G + K A +P E+ +
Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749
Query: 1442 --HTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHD-----VRSLIGSPGRTFPPV 1494
P+ P +P + + K D +S S+ + +++ P ++FPP
Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809
Query: 1495 HPLDVMADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHG 1554
D++A+ R + + S PG +S S G + PV E K Q+ ++ +
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ-KQVDPVQKKEEPKKAQTKMSPK--- 865
Query: 1555 APFAGHLPRGSP------------VTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKS 1602
P A +P+GSP V T + +P+ QE S S +T P+ +
Sbjct: 866 -PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFS--LNLGSITDAPKSQPTT 922
Query: 1603 PHSTV 1607
P TV
Sbjct: 923 PQETV 927
Score = 38.9 bits (89), Expect = 0.065
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 6/72 (8%)
Query: 772 TLGADGPPPGPPTPPPEDIPAPTEPTPASEATGA------PTPPPAPPSPSAPPPVVPKE 825
T G + P P+ P P +P P ++ P PPP PP P PPP P
Sbjct: 2366 TFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Query: 826 EKEEETAAAPPV 837
T+ P +
Sbjct: 2426 PLPPPTSPKPTI 2437
Score = 36.6 bits (83), Expect = 0.32
Identities = 77/367 (20%), Positives = 115/367 (31%), Gaps = 55/367 (14%)
Query: 1946 PKEAPRVARPERPRA-------DTGHAFLAKPPARSGLEPASS--PSKGSEPRPLVPPVS 1996
P EA +++P P+ D KP ++P + S + +P +P
Sbjct: 723 PPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK 782
Query: 1997 GHATIARTPAKNLAPHHASPDPPAPPASAS-DPHREKTQSKPFSIQELELRSLGYHGSSY 2055
+ L A P PP P K +P S ++ + G S
Sbjct: 783 VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI-ISHPGPSSESK 841
Query: 2056 SPEGVEPVSPVSSPSLTHDKGLPK-HLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLR 2114
+ V+PV P K PK + + K P PGP G+ P
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS------PTPPGPRPTAGQTVPTPQQS 895
Query: 2115 PLPESQ--------------PSSSPLL--QTAPGVKGHQRVVTLAQHISEVITQDYTRHH 2158
P P+ Q P S P +T G +Q + + T H
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955
Query: 2159 PQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSE------GGKR 2212
Q S P AP+ P S P P S PP APA+ P + K
Sbjct: 956 SQ--SGP-GAPMKQAPAPSQPPTSQGPPKSTGQAPP----APAKSIPVKKETKAPAAEKL 1008
Query: 2213 SPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPS--------RM 2264
P+ + + E +P + + + AV P + E + +
Sbjct: 1009 EPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNI 1068
Query: 2265 GSKSPGN 2271
GSK P N
Sbjct: 1069 GSKDPPN 1075
Score = 34.3 bits (77), Expect = 1.6
Identities = 14/37 (37%), Positives = 30/37 (81%), Gaps = 3/37 (8%)
Query: 167 LSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEE 203
+++ +++Q+ +DRE+ +VE++ +KL+KKQ +L+EE
Sbjct: 3757 MARAKILQD---IDRELDLVERESAKLRKKQAELDEE 3790
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 82.8 bits (203), Expect = 4e-15
Identities = 113/468 (24%), Positives = 157/468 (33%), Gaps = 66/468 (14%)
Query: 753 SPHTEAAKDTGQNGPKPPATLGAD-----GPPPGPPTPPPEDIPAPTEPTPASEATGAPT 807
+P T+ AK Q P T AD P P+P I PT P ++ G
Sbjct: 264 TPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK 323
Query: 808 PPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECT 867
P P P A P + K ++ PPV+ KPPA + P K
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA---------QPLGPAKPPAQ 374
Query: 868 EEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVD 927
+ E P+ + A A G K ++ G + T + G P+ +
Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT-QQVGTPKPLAQQPGLQSPA-- 431
Query: 928 EAEGGDKNRLLSPRPSLLT---------------PTGDPRANASPQKPLDLKQLKQRAAA 972
+A G K + P P + PT P P KP + A
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP---PPQQPGPAK 488
Query: 973 IPPIVTKVHEPPREDAAPTKPAP--PAPPPPQNLQPESDAP--QQPGSS-PRGKSRSPAP 1027
PP +PP + TKP P P P P QP S P QQPGS+ P + SPA
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
Query: 1028 PADKEAEKPVFFPAFAAEAQKLPGDPPCW---TSGLPFPVPPR-EVIKASPHAPDPSAFS 1083
P+ +++ KPV Q P + GLP + P + H P+ + F+
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 1084 YAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVP 1143
L NP P ++ K L Q+ G VP
Sbjct: 609 TCTECQTTVCSLCG------------FNPNPHLTEVKEWLCLNCQMKRALGGDLAP--VP 654
Query: 1144 YSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESL 1191
S K PVT S + +Q SP+ A P + L
Sbjct: 655 SSPQPKLKTAPVT--------TTSAVSKSSPQPQQTSPKKDAAPKQDL 694
Score = 62.0 bits (149), Expect = 7e-09
Identities = 123/535 (22%), Positives = 184/535 (34%), Gaps = 98/535 (18%)
Query: 668 QHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHAS 727
Q L + + R ++K P + + +++ S + E AL A
Sbjct: 107 QPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAV 166
Query: 728 GNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGP----KPPATLGADGPPPGPP 783
+ V + P + + S+ + + Q P KPP L P P P
Sbjct: 167 SSVVNK---FNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPP--LQQQPPKPIPK 221
Query: 784 TPPPEDIPAPTEPTPASEATGAP----TPPPAPPSPSAPPPVVPKEEKE----EETAAAP 835
P P + TP S ++ P + PP P P P+ + + A+ P
Sbjct: 222 QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
Query: 836 PVEE-----GEEQKP----PAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEAT 886
++ GE KP P+ + T + P + E+++ GPAK A
Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGHEKSQPGPAK------PPAQ 334
Query: 887 AEGALKAEKKEGGSGR------ATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSP 940
G K ++ G+ + TT + + A + E +E L P
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394
Query: 941 RPSLLTPTGDPRANASPQK----PLDLKQ---LKQRAAAIPPIVTKVHEP-----PREDA 988
TP P P + P L Q L+ A A P T V +P P + A
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 989 ----------APTKPAP----PAPPPPQNLQPESDAPQQPGSS--PRGKSRSPAPPADKE 1032
PTKP PA PPPQ P PQQPGS+ P + S PP +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ- 513
Query: 1033 AEKPVFFPAFAAEAQKLPGD--PPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHP 1090
P A + + PG PP G A P A PS +
Sbjct: 514 -------PGPAKPSPQQPGSTKPPSQQPG-----------SAKPSAQQPSPAKPSAQQST 555
Query: 1091 LPLGLHDTARPVLPRPPTISNPPPLISSAKHP--SVLERQIGAISQGMSVQLHVP 1143
P+ + +P+ +PPT+S SAK P L + I + + LHVP
Sbjct: 556 KPVSQTGSGKPL--QPPTVS------PSAKQPPSQGLPKTICPLCNTTELLLHVP 602
Score = 58.9 bits (141), Expect = 6e-08
Identities = 112/499 (22%), Positives = 180/499 (36%), Gaps = 66/499 (13%)
Query: 674 EKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEA-LHASGNEVP 732
EK + K P+ ++ A P ++ G + + + A+ +G+E P
Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 733 RGECSGPATVNNSSDTESIPSPHTEAAKDTGQN--GPKPPATL-GADGPPPGP-PTPPPE 788
E GP + P+ AK Q PKP A G P P PT P
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 789 DIPAPTEPTPASEA---------TGAPTPP---PAPPSPSAPPPVVPKEEKEEETAAAPP 836
P P + PA +A TG PP P P P P K ++ +A PP
Sbjct: 442 QQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 837 VEEGEEQKPPAAEELAVDTGKAE-EPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEK 895
++ KPP + G A+ P + T+ + P K + + A+ + +
Sbjct: 501 SQQPGSTKPPPQQ-----PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 896 K---EGGSGR----ATTAKSSGAPQDSDSSAT----CSADE--VDEAEGGDKNRLLSPRP 942
K + GSG+ T + S+ P T C+ E + E + N +
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615
Query: 943 SLLTPTG-DPRANASPQKP---LDLKQLKQRAAAIPPIVTKVHEPPREDAAP---TKPAP 995
++ + G +P + + K L+ + + + P+ + P+ AP T
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSS--PQPKLKTAPVTTTSAVS 673
Query: 996 PAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPC 1055
+ P PQ P+ DA + S + + P PP K+ P + +A+A++ P
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKP-PPLVKQ---PTLHGSPSAKAKQPPE---- 725
Query: 1056 WTSGLPFPVPPREVIKAS-----PHAPD-PSAFSYAPPGHPLPLGLHDTARPVLPRPPTI 1109
L P PP+E S P A D P P L T +P +P
Sbjct: 726 -ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 1110 S-----NPPPLISSAKHPS 1123
S PPL + + PS
Sbjct: 785 SQAEEKTTPPLKTDSAKPS 803
Score = 58.5 bits (140), Expect = 8e-08
Identities = 92/437 (21%), Positives = 149/437 (34%), Gaps = 48/437 (10%)
Query: 752 PSPHTEAAKDTGQNGPKPPATLGAD-GPPPGPPTPPPEDIPAPT-----EPTPASEATGA 805
P+PH K+ + LG D P P P P + P T + +P + T +
Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT-S 683
Query: 806 PTPPPAP-------PSPSAPPPVV--PKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTG 856
P AP P P PPP+V P A P E KP +E +V +
Sbjct: 684 PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE 743
Query: 857 KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSD 916
+ + PV + ++ + ++ AT + + + K + + TT P +D
Sbjct: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-----PLKTD 798
Query: 917 SSATCSADEVDEAEGGDKNRLLSPRP---SLLTPTGDPRANASPQKPLDLKQLKQRAAAI 973
S+ + + + PRP S + P + + QK +D Q K+
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE---- 854
Query: 974 PPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEA 1033
P + P+ DA P P PP P+ ++ Q P+ +SR +
Sbjct: 855 -PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
Query: 1034 EKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKAS---PHAPDPSAFSYAPPGHP 1090
+ P + P P +G F +AS A P S + PG P
Sbjct: 914 DAP----------KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
Query: 1091 LPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKA 1150
+ P +PPT PP A + ++ + + P +E A
Sbjct: 964 M------KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT 1017
Query: 1151 PVGPVTMGLPLPMDPKK 1167
T P P+ K
Sbjct: 1018 VKRTETEKKPPPIKDSK 1034
Score = 54.7 bits (130), Expect = 1e-06
Identities = 114/547 (20%), Positives = 177/547 (32%), Gaps = 75/547 (13%)
Query: 1741 LSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTH--LTKPTTT 1798
+S+ LP P + +M R L ++ P + S P PG P L+K TT
Sbjct: 60 MSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPP---KQSGRPPDPGRPAQPGLSKSRTT 116
Query: 1799 SSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPG--TEQSSGSSGSSGGGGGSSS 1856
+ E+ ++S + EH PG +E ++ S+ SS +
Sbjct: 117 DTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPF 176
Query: 1857 RPASHSHAHQHSPISPRT-------------QDALQQRPS--VLHNTG-------MKGII 1894
S S A Q + + LQQ+P + G G
Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP 236
Query: 1895 TAVEPSTPTVLRST--STSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV 1952
++ P ++S T P++ P H L D P + ++ E+ +
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
Query: 1953 ARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPH 2012
+ P + KPPA+ +P S+ +P P +A+ P P
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQ---QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 2013 H--ASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPS 2070
+ PPA P + P ++T S+ S ++ ++L +P P P
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP-GPAKPP- 411
Query: 2071 LTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTA 2130
T G PK L + +P P K G P P+ + P P Q
Sbjct: 412 -TQQVGTPKPLAQ----------QPGLQSPAKAPG-----PTKTPVQQPGPGKIPAQQAG 455
Query: 2131 PGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDL---RRPP 2187
PG Q Q P QL P P PG + P +PP
Sbjct: 456 PGKTSAQ--------------QTGPTKPPSQLPGPAKPPPQQ-PGPAKPPPQQPGSAKPP 500
Query: 2188 SDL---YLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHS 2244
S PPP PA+ SP G + P S + + T+P
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Query: 2245 RSAVYPL 2251
+ PL
Sbjct: 561 TGSGKPL 567
Score = 49.7 bits (117), Expect = 4e-05
Identities = 95/390 (24%), Positives = 139/390 (35%), Gaps = 79/390 (20%)
Query: 857 KAEEPVKSECTEE---AEEGPAKGKDAEAAEATAEGALKA--EKKEGGSGRATTAKSSGA 911
K E PV + + +E+ P K E L+A +KKE + R ++ S
Sbjct: 2280 KPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETV 2339
Query: 912 PQDSDSS--ATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQR 969
SS A +++ +P+ P+G P ++ P KP +
Sbjct: 2340 FDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSL 2399
Query: 970 AAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR-----GKSRS 1024
+ P PP P PP PPPP P P P +SP+ K +
Sbjct: 2400 DISAQP-------PP--------PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT 2444
Query: 1025 PAPPADKEAEKPVFFPAFAAE------AQKLPGDPPCWTSGLPFPVPPREVIKASPHAPD 1078
A P P+F E + LP C T+ P PVPP+
Sbjct: 2445 VASPV--TTATPLFDAVTTLETTAVLRSNGLPVTRICTTA--PPPVPPK----------- 2489
Query: 1079 PSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNP--PPLISSAKHPSVLERQIGAISQGM 1136
PS+ +P GL T RP +PP P P L ++ + P+ + + +S
Sbjct: 2490 PSS---------IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540
Query: 1137 SVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPR-----GQAGPPESL 1191
S+ L++ S K LP P P L+P S + S P
Sbjct: 2541 SMTLNLVTSADYK---------LPSPTSP--LSPHSNKSSPRFSKSLTETYVVITLPSEP 2589
Query: 1192 GVPTAQEASVLRGTALGSVPGGSITKGIPS 1221
G PT AS A+ S P GS +K + S
Sbjct: 2590 GTPTDSSAS----QAITSWPLGSPSKDLVS 2615
Score = 46.2 bits (108), Expect = 4e-04
Identities = 25/66 (37%), Positives = 29/66 (43%), Gaps = 21/66 (31%)
Query: 773 LGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKE---EKEE 829
+ A PPP PP PPP P PPP PP P PPP PK K++
Sbjct: 2401 ISAQPPPPPPPPPPP------------------PPPPPPPPPPPLPPPTSPKPTILPKKK 2442
Query: 830 ETAAAP 835
T A+P
Sbjct: 2443 LTVASP 2448
Score = 45.8 bits (107), Expect = 5e-04
Identities = 85/467 (18%), Positives = 182/467 (38%), Gaps = 64/467 (13%)
Query: 183 ITMVEQQISKLKKKQQQLEEEAAKPPE--PEKPVSPPPIESKHRSLVQIIYDENRKKAEA 240
++++E Q S L ++ E+ +P E PE+P +S +L I +E K+++
Sbjct: 1417 LSILEAQASTLADEKS---EKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQE 1473
Query: 241 AHRILEGLGPQVELP----------LYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHA 290
+ Q ++P + + R+ +++++ + + KRR
Sbjct: 1474 ERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSV 1533
Query: 291 RKQWEQKFCQRYDQLMEAWEKKVER--IENNPRRRAKESKVREYYEKQFPEIRKQRELQE 348
++ Q Q E + + IE + A S+ E+ Q EI E Q+
Sbjct: 1534 GSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQK 1593
Query: 349 RMQSR-------------VGQRGSGLSMSAAR------SEHEVSEIIDGLSEQENLEKQM 389
+ +++ + + + A R + E + L +E ++
Sbjct: 1594 KEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQES 1653
Query: 390 RQLAVIPPMLYDADQQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHP- 448
+L V +R K I +N +AD ++ +++ ++E E E P
Sbjct: 1654 EELVVTG----GGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPE 1709
Query: 449 -KNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQ 507
++ G +S L + ++ +E+ S K + +QQ++ + +
Sbjct: 1710 DRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHK-----KGESKQQRKARHRPHG 1764
Query: 508 QQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASK 567
P S EE++ +E+E+ +++E++ E+E + ++ + S +D DE A
Sbjct: 1765 PLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQ----RKSSSKKSKKDKDELRA---- 1816
Query: 568 GRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASM-ELNESS 613
RR+ R +N + E+A ++ + A M EL+ SS
Sbjct: 1817 --------QRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855
Score = 44.3 bits (103), Expect = 0.002
Identities = 51/240 (21%), Positives = 92/240 (38%), Gaps = 28/240 (11%)
Query: 809 PPAPPSPSAPPPVVPKEEKEEETAAAPP---VEEGEEQKPPAAEELAVDTGK---AEEPV 862
PPAP P A P VP E ++TA P V++ E++ AE++ ++ K + E +
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKI 1185
Query: 863 KSECTEEAEEGPAKGKDAEAAEATAEGALKAEKK--------EGGSGRATTAKSSGAPQD 914
T + ++ +K + +A+ + L EKK + + P+D
Sbjct: 1186 PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPED 1245
Query: 915 SDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIP 974
+E K+ LL + + + R +P+ + KQ + + +P
Sbjct: 1246 KKLLPEAKTSAPEE----QKHDLLKSQVQIAEEKLEGR--VAPKTVQEGKQPQTKMEGLP 1299
Query: 975 PIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAP------QQPGSSPRGKSRSPAPP 1028
+ P+ED TK P PP +P+ P ++ S S+ P P
Sbjct: 1300 SGTPQ--SLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Score = 42.7 bits (99), Expect = 0.004
Identities = 41/179 (22%), Positives = 58/179 (32%), Gaps = 41/179 (22%)
Query: 679 ARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSG 738
A R KK+ A ++ + V + + E+ + G E P +
Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPS 2378
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTP 798
+ +S + P + + + Q P PP PPP PP PPP +P PT P P
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP---PPPPPPPPPPPPPPLPPPTSPKP 2435
Query: 799 ----------ASEATGA----------------------------PTPPPAPPSPSAPP 819
AS T A PPP PP PS+ P
Sbjct: 2436 TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIP 2494
Score = 42.0 bits (97), Expect = 0.008
Identities = 107/498 (21%), Positives = 161/498 (32%), Gaps = 106/498 (21%)
Query: 787 PEDIPAPTEPTPASEATGAPTPPPAP----------------------------PSPSAP 818
PE + A + G+P+ P P S P
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP 72
Query: 819 PPVVPK---EEKEEETAAAPPVEEGEEQKP--PAAEELA----VDTGKAEE--PVKSECT 867
P K+E ++ PP + G P PA L+ DT ++E+ P +S T
Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132
Query: 868 EEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSA----TCSA 923
+E ++ E +++ +E + + K + SDS A T
Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192
Query: 924 DEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLD--------LKQLKQRAAAIPP 975
+V + E G ++ P P P+ + PL Q ++ + PP
Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252
Query: 976 IVTKVHEPP--------------REDAAP------------TKPAPPAP--PPPQNLQPE 1007
K + P R+ + P KP+ P+P PP Q P
Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312
Query: 1008 SDAPQQPG--SSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPV- 1064
QQPG S G ++ PA P+ KP+ A K P PP T P+
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSG--LTKPL---AQQPGTVKPPVQPPGTTKPPAQPLG 367
Query: 1065 ---PPREVI---KASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT--------IS 1110
PP + K S P P A + PPG +G +P +PPT ++
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALA-QPPG----VGKTPAQQPGPAKPPTQQVGTPKPLA 422
Query: 1111 NPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAP 1170
P L S AK P + + G + + GP LP K
Sbjct: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 1171 FSGVKQEQLSPRGQAGPP 1188
G + G A PP
Sbjct: 483 QPGPAKPPPQQPGSAKPP 500
Score = 41.2 bits (95), Expect = 0.013
Identities = 61/299 (20%), Positives = 96/299 (32%), Gaps = 18/299 (6%)
Query: 741 TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTE----P 796
T + S + + P ++K Q K L D P PP + +P + P
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 797 TPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTG 856
PAS++ P P+ S V P ++KEE A + + KP T
Sbjct: 823 RPASDSKIISHPGPSSES-KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS---PTP 878
Query: 857 KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRAT-TAKSSGA---- 911
P + ++ P + + A K + + + T T K G
Sbjct: 879 PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI 938
Query: 912 -PQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRA 970
Q S+ +T G +P PS + P + P K + +
Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKK 998
Query: 971 AAIPPIVTKVHEPPREDAAPT--KPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAP 1027
P K+ P+ + APT + PPP A Q P +SP P
Sbjct: 999 ETKAPAAEKLE--PKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKP 1055
Score = 40.8 bits (94), Expect = 0.017
Identities = 79/369 (21%), Positives = 131/369 (35%), Gaps = 56/369 (15%)
Query: 509 QQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKED---LLKEKTDDTSGEDNDEKEAVA 565
+QP P + K KE E++K V +DK ++K TD S K +
Sbjct: 721 KQP-PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP 779
Query: 566 SKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKK 625
S ++ +EE TP + S + ++S T E++
Sbjct: 780 SS-------------------KVQSQAEEKTTPPLKTD--SAKPSQSFPPTGEKVSPFDS 818
Query: 626 GLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKK 685
+ + S I G + S K ++ +D + ++ + K + + + + K
Sbjct: 819 KAIPRPASDSKIISHPGPSSES---------KGQKQVDPVQKKEEPKKAQTKMSPKPDAK 869
Query: 686 APAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPA-TVNN 744
S P + + S +E S + P+ + + P TV
Sbjct: 870 PMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG 929
Query: 745 S--SDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEA 802
SI S + GQ GP + GA P + PAP++P P S+
Sbjct: 930 KLFGFGASIFSQASNLISTAGQPGPHSQSGPGA----------PMKQAPAPSQP-PTSQG 978
Query: 803 TGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPV 862
T APP+P+ PV +KE + AA +E EQ P +T K P+
Sbjct: 979 PPKSTGQ-APPAPAKSIPV----KKETKAPAAEKLEPKAEQAPTVKR---TETEKKPPPI 1030
Query: 863 KSECTEEAE 871
K + AE
Sbjct: 1031 KDSKSLTAE 1039
Score = 40.4 bits (93), Expect = 0.022
Identities = 49/218 (22%), Positives = 84/218 (38%), Gaps = 29/218 (13%)
Query: 667 QQHKLKMEKER-NARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALH 725
+Q + K+EK++ +A ++KK P EE P E+E++ S ++ ++EE +
Sbjct: 1194 KQEESKLEKDKASALQEKKPLP----EEKKLIP--EEEKIR----SEEKKPLLEEKKPTP 1243
Query: 726 ASGNEVPRGECSGPATVNNSSDTESIPSPHTE----AAKDTGQNGPKPPATLGADGPPPG 781
+P + S P + + + A T Q G +P + G
Sbjct: 1244 EDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKM------EG 1297
Query: 782 PPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGE 841
P+ P+ +P + T T P PP + P V P +EK E+ +
Sbjct: 1298 LPSGTPQSLPKEDDKT-----TKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQ 1352
Query: 842 EQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKD 879
+ K P DTG + + + S E P KD
Sbjct: 1353 QPKSPQG---LSDTGYSSDGISSSLGEIPSLIPTDEKD 1387
Score = 38.9 bits (89), Expect = 0.065
Identities = 55/245 (22%), Positives = 96/245 (39%), Gaps = 40/245 (16%)
Query: 1396 PSRDLTEAYKTQALGPLKLKPAHEGLVATV-----------KEAGRSIHEIPREELR--- 1441
P +DL++A + + PL +P G + K A +P E+ +
Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749
Query: 1442 --HTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHD-----VRSLIGSPGRTFPPV 1494
P+ P +P + + K D +S S+ + +++ P ++FPP
Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809
Query: 1495 HPLDVMADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHG 1554
D++A+ R + + S PG +S S G + PV E K Q+ ++ +
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ-KQVDPVQKKEEPKKAQTKMSPK--- 865
Query: 1555 APFAGHLPRGSP------------VTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKS 1602
P A +P+GSP V T + +P+ QE S S +T P+ +
Sbjct: 866 -PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFS--LNLGSITDAPKSQPTT 922
Query: 1603 PHSTV 1607
P TV
Sbjct: 923 PQETV 927
Score = 38.9 bits (89), Expect = 0.065
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 6/72 (8%)
Query: 772 TLGADGPPPGPPTPPPEDIPAPTEPTPASEATGA------PTPPPAPPSPSAPPPVVPKE 825
T G + P P+ P P +P P ++ P PPP PP P PPP P
Sbjct: 2366 TFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Query: 826 EKEEETAAAPPV 837
T+ P +
Sbjct: 2426 PLPPPTSPKPTI 2437
Score = 36.6 bits (83), Expect = 0.32
Identities = 77/367 (20%), Positives = 115/367 (31%), Gaps = 55/367 (14%)
Query: 1946 PKEAPRVARPERPRA-------DTGHAFLAKPPARSGLEPASS--PSKGSEPRPLVPPVS 1996
P EA +++P P+ D KP ++P + S + +P +P
Sbjct: 723 PPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK 782
Query: 1997 GHATIARTPAKNLAPHHASPDPPAPPASAS-DPHREKTQSKPFSIQELELRSLGYHGSSY 2055
+ L A P PP P K +P S ++ + G S
Sbjct: 783 VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI-ISHPGPSSESK 841
Query: 2056 SPEGVEPVSPVSSPSLTHDKGLPK-HLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLR 2114
+ V+PV P K PK + + K P PGP G+ P
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS------PTPPGPRPTAGQTVPTPQQS 895
Query: 2115 PLPESQ--------------PSSSPLL--QTAPGVKGHQRVVTLAQHISEVITQDYTRHH 2158
P P+ Q P S P +T G +Q + + T H
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955
Query: 2159 PQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSE------GGKR 2212
Q S P AP+ P S P P S PP APA+ P + K
Sbjct: 956 SQ--SGP-GAPMKQAPAPSQPPTSQGPPKSTGQAPP----APAKSIPVKKETKAPAAEKL 1008
Query: 2213 SPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPS--------RM 2264
P+ + + E +P + + + AV P + E + +
Sbjct: 1009 EPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNI 1068
Query: 2265 GSKSPGN 2271
GSK P N
Sbjct: 1069 GSKDPPN 1075
Score = 34.3 bits (77), Expect = 1.6
Identities = 14/37 (37%), Positives = 30/37 (81%), Gaps = 3/37 (8%)
Query: 167 LSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEE 203
+++ +++Q+ +DRE+ +VE++ +KL+KKQ +L+EE
Sbjct: 3757 MARAKILQD---IDRELDLVERESAKLRKKQAELDEE 3790
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 82.0 bits (201), Expect = 7e-15
Identities = 142/557 (25%), Positives = 181/557 (32%), Gaps = 126/557 (22%)
Query: 743 NNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPP---------------- 786
N ++ + T AA+ G P+PP G+ PPP P TP
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPP---GSPRPPP-PVTPAALRVLGAAGAVGRKPL 58
Query: 787 ------------PEDIP--APTEPTPASEATGAPTPPP------APPSPSAPPPVVPKEE 826
PE P PT S A PP APP+ + P V
Sbjct: 59 AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118
Query: 827 KEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEAT 886
+ T P+ G++ +AEE V GKA E K G
Sbjct: 119 RASGTTRPGPL--GQKGLRISAEE-TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Query: 887 AEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAE-----------GGDKN 935
+A E G R + P + + SA E E GG
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 936 R------------LLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEP 983
R L SP S + G PRA A P +P + K A PP VT P
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP----KPKGLQALRPPQVT----P 287
Query: 984 PREDAAP----------TKPAPPA-----PPPPQNLQPESD------------APQQPGS 1016
PR+DAAP P+P A PP P S AP P S
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP-S 346
Query: 1017 SPRGKSRSPAPPA--DKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFP-------VPPR 1067
+P P+PPA +A + P A LP PP P P +PP
Sbjct: 347 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP-SPPLSPLATPPPQAPPALALPPL 405
Query: 1068 EVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRP-PTISNP------PPLISSAK 1120
+ + P +P S + P P L +H P P P P + P PP+ SA
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
Query: 1121 HPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLS 1180
PS + A L VP S A P+ P P P P K +
Sbjct: 466 PPSQAPPSLAA------PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519
Query: 1181 PRGQAGPP-ESLGVPTA 1196
P A PP ++L P A
Sbjct: 520 PPALATPPLQALPSPPA 536
Score = 81.3 bits (199), Expect = 1e-14
Identities = 124/510 (24%), Positives = 166/510 (32%), Gaps = 83/510 (16%)
Query: 779 PPGPPTPPPEDIPAPTEPT---------PASEATGAPTPPPAPPSPSAPPPVVPKEEKEE 829
PPG P PPP PA P +E G P S P
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 830 ETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEE------------AEEGPAKG 877
A+ PP E+ PPA G P ++ T AEE A+G
Sbjct: 89 NPASRPPASGRGERAPPAKN---TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 145
Query: 878 KDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSAT--------CSADEVDEA 929
K A EA AL A + SG S + S ++ T SA
Sbjct: 146 K---ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 930 EGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAA 989
EG K+ + S P+ R S L + +++ P+ + P
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 990 PTKPAPPAPPPPQNLQ---------PESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFP 1040
P PA P+ P P+ LQ P DA G +P+P A +++ P P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322
Query: 1041 AFAAE-------AQKLPGDPPCWTS-----GLPFP--VPPREVIKA--SPHAPDPSAFSY 1084
A A LP PP ++ LP P PP + + SP +F
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 382
Query: 1085 APPGHPL----PLGLHDTARPVLPRPPTISNPPPL----ISSAKHPSVLERQI--GAISQ 1134
+PP PL P A P L PP+ PPL S + P+ L + S
Sbjct: 383 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 442
Query: 1135 GMSVQLHVPYSEHAKAPVGP------------VTMGLPLPMDPKKLAPFS-GVKQEQLSP 1181
S + P+S A PV P L +P P P S +P
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502
Query: 1182 RGQAGPPESLGVPTAQEASVLRGTALGSVP 1211
A PP L P Q L L ++P
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALP 532
Score = 68.9 bits (167), Expect = 6e-11
Identities = 118/503 (23%), Positives = 177/503 (35%), Gaps = 81/503 (16%)
Query: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTP 798
PAT ++SS T + +P A PP+ PP PP+ + +PT
Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSA----PPSLQTLPSPPATPPSQATTSLGSPTLQAT 377
Query: 799 ASEATGAPTPPPAPPSPSAPPPV-VPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGK 857
S P P A P P APP + +P + A+PP+ P A LAV +
Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
Query: 858 A------EEPVKSECTEEAEE--GPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSS 909
A PV++ + A P+ ++A + A L+ S A+ S
Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP----SPPASPPMSP 493
Query: 910 GAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDL--KQLK 967
A + +A + +L P P P A P P +
Sbjct: 494 SATPPPQAPPPLAAPPL---------QLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544
Query: 968 QRAAAIP--PIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSP 1025
+A++P P+ T + P AAP PP+PP LQ AP++P P
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ----APRRP----------P 590
Query: 1026 APPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYA 1085
P D P A A PG PP PP ++ PD + S +
Sbjct: 591 TPGPDTSVSGPRLTLALA------PGPPP----------PPSRSPSSTLSGPDLAGHSSS 634
Query: 1086 PPGHPLPLGLHDTARPVLPRPPTISNPPPLIS-SAKHPSVLERQIGAISQGMSVQLHVPY 1144
P L +D+ P ++PPP +A HP+ A S+G + L
Sbjct: 635 ATSTPEELRGYDSG----PEGGAAASPPPDAELAACHPA-------AWSRGPAPPLAFRG 683
Query: 1145 SEHAKAPVGPVT-----MGLPLPMD---PKKLAPFSGVKQEQLSPRGQAGPPESLGVPTA 1196
+ A P P T GL + P+ P G SP G +G + G
Sbjct: 684 APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP-GTSGGKAAAGAGAG 742
Query: 1197 QEASVLRGTALGSVPGGSITKGI 1219
+ + LG +P G++ +
Sbjct: 743 ASSRSPKQARLGELPLGALQASV 765
Score = 68.2 bits (165), Expect = 1e-10
Identities = 134/560 (23%), Positives = 172/560 (30%), Gaps = 94/560 (16%)
Query: 683 KKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATV 742
K +P S + G+ + EE V +A A R S A
Sbjct: 107 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP----KRSALSAGARR 162
Query: 743 NNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEA 802
+ S T PSP A G G P P P P P P
Sbjct: 163 DTSGPTPGTPSPAMARRSR-------------AAGTEVGLPRPAPSARPRPPTEGPRKSV 209
Query: 803 TGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPV 862
+ A PSP+ A P G Q+ PA+ L+ P
Sbjct: 210 SSASEHSTTEPSPA---------------ARRRPSAGGGLQR-PASRSLSSSATPLSSPA 253
Query: 863 KSECTEEAEEGP-AKG---KDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSS 918
+S GP A+G A ++ +G + R A + G P S
Sbjct: 254 RS--------GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG-PLSSSPL 304
Query: 919 ATCSADEVDEAEGGDKNRLLSPRPSLLT---PTGDPRANASPQKPLDLKQLKQRAAAIP- 974
AT S +++ +P S LT T P A SP P L+ L A P
Sbjct: 305 ATPSPSAALQSQ-APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
Query: 975 --------PIVTKVHE-PPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSP 1025
P + H P +P PP PP L P P P S P +P
Sbjct: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
Query: 1026 APPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYA 1085
+P A A A + P PP P PP + SP A P + S
Sbjct: 424 SPQAPN---------ALAVHLLQAPFSPP--------PSPPVQA-PFSPPASPPVSPSAT 465
Query: 1086 PPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYS 1145
PP P A P L PP+ PP+ SA P + A +QL P
Sbjct: 466 PPSQAPP----SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA----PPLQLAKPPP 517
Query: 1146 EHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGT 1205
+ A P LP P P S Q SP P L P Q VL
Sbjct: 518 QAPPALATPPLQALPSP-------PASFPGQAPFSPSASL-PMSPLATPPPQAPPVLAAP 569
Query: 1206 ALGSVPGGSITKGIPSTRVP 1225
L P + + + R P
Sbjct: 570 LLQVPPSPPASPTLQAPRRP 589
Score = 58.9 bits (141), Expect = 6e-08
Identities = 172/729 (23%), Positives = 242/729 (33%), Gaps = 159/729 (21%)
Query: 1826 TTVEHAPIWRPGTEQSSGSSGSS------GGGGGSSSRPASHSHAHQHSPISPRTQDALQ 1879
T E AP R G +S+G+S + G G + PA ++ P+S + +
Sbjct: 69 TIPESAP--RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP---GPVSSPGRASGT 123
Query: 1880 QRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPA--THCPLGGTLDGVYP 1937
RP L G KG+ + E TV R +T +P R A + T P GT
Sbjct: 124 TRPGPL---GQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
Query: 1938 TLMEP----VLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSK-----GSEP 1988
V LP+ AP ARP RP + ++ S EP+ + + G
Sbjct: 178 RRSRAAGTEVGLPRPAPS-ARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 1989 RPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSL 2048
RP +S AT +PA++ +P PA P+ Q KP +Q L +
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS----------QPKPKGLQALRPPQV 285
Query: 2049 GYHGSSYSPE-GVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEA 2107
+P G SP+++PS + L+ + P P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPS--------------PSAALQSQAPPTLPATPHSSSLT 331
Query: 2108 AHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLP 2167
L PL PS+ P LQT P +Q + + + H S PL
Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPA----TPPSQATTSLGSPTLQATHSFLPSPPL- 386
Query: 2168 APLYSFPGASCPVL---DLRRPPSDLYLPP------PDHGAPARGSPHSEGGKRSPEPNK 2218
+PL + P + P L L+ PPS PP P AP + H SP P+
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 446
Query: 2219 TSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAF 2278
P SPP P S SA P S++P + + PP
Sbjct: 447 PVQA--------PFSPP---ASPPVSPSATPP---------------SQAPPSLAAPPLQ 480
Query: 2279 FSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQA 2338
++ M S T P ++ P ++ P L T QA
Sbjct: 481 VPPSPPASPPMSPSA---------TPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPLQA 530
Query: 2339 VQEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSD 2398
+ SPP S P + SASLP + P+ ++
Sbjct: 531 LP--------------------------SPPASFPGQAPFSPSASLPMS-PLATPPPQAP 563
Query: 2399 HTLTSPGGGGKAKVSGRP---SSRKAKSPAP-----------GLASGDRPPSVSSVHSEG 2444
L +P P + R+ +P P LA G PP S S
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS-- 621
Query: 2445 DCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHA 2504
L+ SSA STP + G ASPPP A P A
Sbjct: 622 ------TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA-----A 670
Query: 2505 WDEEPKPLL 2513
W P P L
Sbjct: 671 WSRGPAPPL 679
Score = 57.8 bits (138), Expect = 1e-07
Identities = 136/579 (23%), Positives = 190/579 (32%), Gaps = 131/579 (22%)
Query: 1753 PTPGTPATAMDRLAYLPTA----PQPFSSRHSSSPLSPGGP----THLTKPTTTSSSERE 1804
PTPGTP+ AM R + P+P S P GP + ++ +TT S
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE--GPRKSVSSASEHSTTEPSPAA 224
Query: 1805 RDRDR-----ERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPA 1859
R R +R R S ++ P R GT ++ G + RP
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPP 283
Query: 1860 SHSHAHQHS-----PIS------PRTQDALQ-QRPSVLHNTGMKGIITAVEPSTPTVLRS 1907
+ + + P+S P ALQ Q P L T +T + +TP L
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC-QLATPLPLAP 342
Query: 1908 TSTSSPVR------PAATFPPATHCPLGG-TLDGVYPTLMEPVLLPKEAPRVARPERPRA 1960
S S+P P AT P LG TL + L P L P P P+ P A
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP---PQAPPA 399
Query: 1961 DTGHAFLA--KPPARSGLEPASSPSKGSE--------------------PRPLVPPVSGH 1998
A PPA L P ++PS + P PP S
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459
Query: 1999 ATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS------------------- 2039
+ + TP P A+P PP+ + P + + P
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519
Query: 2040 --------IQELELRSLGYHGSS-YSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKS--- 2087
+Q L + G + +SP P+SP+++P L L ++ S
Sbjct: 520 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579
Query: 2088 --HLEGELRPKQPGP-VKLGGEAAHLPHLRPLPESQPSSSP-LLQTAPGVKGHQRVVTLA 2143
L+ RP PGP + G L L P P PS SP + P + GH T
Sbjct: 580 SPTLQAPRRPPTPGPDTSVSGPRLTLA-LAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 638
Query: 2144 QH--------------ISEVITQDYTRHHPQQLS--------------APLPAPLYSFPG 2175
S + HP S APLP P + PG
Sbjct: 639 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698
Query: 2176 AS---CPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGK 2211
++ C + + P S P P SP + GGK
Sbjct: 699 SADGLCTIYETEGPESATPAPGALDPGP---SPGTSGGK 734
Score = 37.7 bits (86), Expect = 0.14
Identities = 82/348 (23%), Positives = 114/348 (32%), Gaps = 69/348 (19%)
Query: 2174 PGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVS 2233
P A P L RPP PPP A R + R P + +GG I +
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT--IPESA 74
Query: 2234 PPEGMTEPGHSRS---AVYPLLYRDGEQTEPSRMGSKSP-------GNTSQPPAFFSK-- 2281
P G T + S A P GE+ P++ S P T++P K
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 2282 LTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQE 2341
+ + + K E K+ + + PGT PA M RS+A
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP---SPA------MARRSRA--- 182
Query: 2342 HASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHTL 2401
A T +GL P A + P P P + S+H+
Sbjct: 183 -AGTEVGL-------------------PRPAPSARP-----RPPTEGPRKSVSSASEHST 217
Query: 2402 TSPGGGGKAKVSG-----RPSSRKAKSPAPGLASGDR-----------PPSVSSVHSEGD 2445
T P + + S RP+SR S A L+S R P S +G
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 2446 CNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPA 2493
R P +D + G P +PL + + S PP LPA
Sbjct: 278 QALRPPQVTPPRKDAAPALG--PLSSSPLATPSPSAALQSQAPPTLPA 323
Score = 36.2 bits (82), Expect = 0.42
Identities = 47/198 (23%), Positives = 67/198 (33%), Gaps = 9/198 (4%)
Query: 697 PPVVEDEEMEASG-VSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPH 755
PPV AS VS + + +L A +VP + P +++ P P
Sbjct: 446 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 505
Query: 756 TEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIP--APTEPTPASEATGAPTPPPAPP 813
+ P+ P L PP PP P AP P+ + + TPPP P
Sbjct: 506 AAPPLQLAKPPPQAPPALAT--PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 563
Query: 814 SPSAPPPV-VPKEEKEEETAAAP--PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEA 870
A P + VP T AP P G + + L + P S
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS-VSGPRLTLALAPGPPPPPSRSPSST 622
Query: 871 EEGPAKGKDAEAAEATAE 888
GP + +A +T E
Sbjct: 623 LSGPDLAGHSSSATSTPE 640
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 82.0 bits (201), Expect = 7e-15
Identities = 163/738 (22%), Positives = 261/738 (35%), Gaps = 112/738 (15%)
Query: 478 NYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPE 537
+Y + S R + QQ +++ Q+ + + EEK E + +E EEK
Sbjct: 40 SYSAKAYESIRVSSELQQTWTKRKHGQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSA 99
Query: 538 VENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAIT 597
+ L E D N + + + Q R G T M N E+ +
Sbjct: 100 DVREAAIELPESVQDVEIPPNIPSVQL----KMDRSQQTSRTGYWT--MMNIPPVEK-VD 152
Query: 598 PQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIA-------------RMVGSK 644
+Q + E+ SR + +K+ L+H + A +G K
Sbjct: 153 KEQQTYFSESEIVVISR-PDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQK 211
Query: 645 TVSQCKNFYFNYKKRQNL---DEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVE 701
+S+ +F KK + DE+ ++ + + +E +A +K A FP ++
Sbjct: 212 NISRT-SFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQ 270
Query: 702 DEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKD 761
+E + E + S E P E + A NS + P+ +
Sbjct: 271 PPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAA-TAVAENSVKVQPPPAEEAPLVEF 329
Query: 762 TGQNGP-----KPPATLGADGPPPGPPT-----PPPEDIPAPTEPTPASEATG---APTP 808
+ P P L A+ PP PP E +P P E +P+ E G +P+
Sbjct: 330 PAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSA 389
Query: 809 PPAP---------------PSPSAPP----------PVVPKEEKEEE-------TAAAPP 836
AP P+ PP P++P+E EE TA P
Sbjct: 390 QKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETP 449
Query: 837 VEEG-EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEK 895
EE E + P +E + AE + + A+E PA+ + + E +AE A AE
Sbjct: 450 AEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEA-HAEV 508
Query: 896 KEGGSGRATTAKSSG---------APQD-------SDSSATCSADE--VDEAEGGDKNRL 937
+ + T ++S AP D S S SA+E + K
Sbjct: 509 QSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVS 568
Query: 938 LSPRP-SLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPP 996
+ P L P+G+ + L + +A P +V PP E+A PP
Sbjct: 569 IEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAP--AEVQPPPAEEAPAEVQPPP 626
Query: 997 APPPPQNLQP----ESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPG- 1051
A P +QP E+ A QP + + PPA+ E P AE Q P
Sbjct: 627 AEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE---EAP-------AEVQPPPAE 676
Query: 1052 DPPCWTSGLPFPVPPREVIKASPHAP---DPSAFSYAPPGHPLPLGLHDTARPVLPRPPT 1108
+ P LP P E A+ H+P D A + H P L T +
Sbjct: 677 EAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASA 736
Query: 1109 ISNPPPLISSAKHPSVLE 1126
+PPP + + +++E
Sbjct: 737 EVSPPPSEQTPEDEALVE 754
Score = 38.1 bits (87), Expect = 0.11
Identities = 70/344 (20%), Positives = 113/344 (32%), Gaps = 39/344 (11%)
Query: 509 QQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKG 568
Q P+P+ + E+ E + A E E + L E+T +E A
Sbjct: 458 QSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSA------EEAHAEVQSP 511
Query: 569 RKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGLL 628
+ I A EA ++E TP ++ S E + E + +AK +
Sbjct: 512 LAEETTAEEASAEIQLLAAIEAPADE--TPAEAQSPLSEETSAEEAPAEVQSPSAKGVSI 569
Query: 629 EHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPA 688
E + G +T ++ + +++ A + + PA
Sbjct: 570 EEAP--LELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPA 627
Query: 689 AASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDT 748
+ PP E+ E E AE E P E P ++
Sbjct: 628 EEAPAEVQPPPAEEAPAEVQPPPAEEAP----AEVQPPPAEEAP-AEVQPPPAEEAPAEV 682
Query: 749 ESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTP----------PPEDIPAPTEPTP 798
+S+P+ T + TL A PP P PP D+ TE P
Sbjct: 683 QSLPAEETPIEE-----------TLAAVHSPPADDVPAEEASVDKHSPPADL-LLTEEFP 730
Query: 799 ASEATGAPTPPPAPPSPSAPPPV--VPKEEKEEETAAAPPVEEG 840
EA+ +PPP+ +P V V E + + A P V+ G
Sbjct: 731 IGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLG 774
Score = 37.0 bits (84), Expect = 0.25
Identities = 54/242 (22%), Positives = 82/242 (33%), Gaps = 30/242 (12%)
Query: 1792 LTKPTTTSSSERERD----RDRERDRDREREKSILTSTTTVE--HAPIWRPGTEQSSGSS 1845
L K TT + E + D +S L+ T+ E HA + P E+++
Sbjct: 461 LPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEE 520
Query: 1846 GSSGGGG-GSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTV 1904
S+ + PA + A SP+S T + ++ P+ + + KG+
Sbjct: 521 ASAEIQLLAAIEAPADETPAEAQSPLSEET--SAEEAPAEVQSPSAKGV----------- 567
Query: 1905 LRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGH 1964
S P PP+ L +EAP +P P A+
Sbjct: 568 ------SIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQP--PPAEEAP 619
Query: 1965 AFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATI-ARTPAKNLAPHHASPDPPAPPA 2023
A + PPA P P + PP + A + P AP P PPA A
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQP-PPAEEA 678
Query: 2024 SA 2025
A
Sbjct: 679 PA 680
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 80.5 bits (197), Expect = 2e-14
Identities = 112/578 (19%), Positives = 242/578 (41%), Gaps = 65/578 (11%)
Query: 170 EELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQI 229
EEL + D + E+ +LKKK +L+E+ + +S +Q+
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLR-------------LAESEKSEIQL 208
Query: 230 IYDENRKKAEAAHRILEGLGPQVEL-----PLYNQPSDTRQYHENIKINQAMRKKLILYF 284
E ++K E A +L PQV+ ++ Q + R+ + I+ + +
Sbjct: 209 NVKELKRKLERAKFLL----PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERL 264
Query: 285 KRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRR----RAKESKVREYYEKQFPEI 340
+ + ++ E+K +R ++ + EK++ E R R +E +++E EK + +
Sbjct: 265 REQEGKMREQEEKM-RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
Query: 341 RKQRELQERM---QSRVGQRGSGLSMSAAR---SEHEVSEIIDGLSEQENLEKQMRQLAV 394
K RE +E+M + R+ ++ + + E + E + L E+E ++ ++
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 383
Query: 395 IPPMLYDAD--QQRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFG 452
+ + + ++R K + + +Q NMW ++EKE +++ + +
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443
Query: 453 LIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPM 512
E++ E + +++ + R+ K ++Q+ Q +Q+++ + Q
Sbjct: 444 EQEKMQEQE---EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Query: 513 PRSSQEEK----DEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKG 568
QEE+ DE+ +EKE E+K + +++ ++KT + + D++E + +
Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 569 RKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEE--METAKKG 626
R + +K R M E EE + Q+ M E W +EE E +K
Sbjct: 561 RM---REREKKMREEEEMMRE--QEEKMQEQEE----KMREQEEKMWEQEEKMQEQEEKM 611
Query: 627 LLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKA 686
+ + W + K Q + + +K Q +E + + + KM ++ R++++
Sbjct: 612 WEQEEKMWE---QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Query: 687 PAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEAL 724
E+ + E EE + G EE+M E+ E +
Sbjct: 669 MQGQEEK-----MREQEEK----MQGQEEKMREQEEKM 697
Score = 71.6 bits (174), Expect = 9e-12
Identities = 99/533 (18%), Positives = 228/533 (42%), Gaps = 65/533 (12%)
Query: 166 RLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRS 225
R +E++ + +R+ + + +Q K+++++++L E+ + E EK + + K R
Sbjct: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE---QKKLRE 307
Query: 226 LVQIIYDENRKKAEAAHRILEGLGP--QVELPLYNQPSDTRQYHENIKINQAMR----KK 279
+ + ++ K E ++ E + E L+ Q R+ + ++ + ++
Sbjct: 308 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER 367
Query: 280 LILYFKRRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAK----------ESKV 329
L +R K WEQ+ + ++ + EKK+ E R + + E +
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427
Query: 330 REYYEKQFPEIRKQRELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQM 389
+E+ +++ PE +++ QE+MQ + E ++ E + + +QE + Q
Sbjct: 428 KEWQQQRLPEQKEKLWEQEKMQEQ---------------EEKIWEQEEKIRDQEEMWGQE 472
Query: 390 RQLAVIPPMLYDADQ---QRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQ 446
+++ M DQ Q K + M D Q MW + E+ +E+ M+
Sbjct: 473 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD--------QEERMWEQDERLREKEERMR 524
Query: 447 HPKNFGLIASFL--ERKTVAECVLYYYLTKKNENYKSLVRRSYRRRGKSQ----QQQQQQ 500
K + E+KT + + +K + + R + R + + Q+++ Q
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584
Query: 501 QQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTD---DTSGED 557
+Q+++ ++Q+ QEEK ++++EK E+EE+ E ++ED ++E+ + + +
Sbjct: 585 EQEEKMREQEE-KMWEQEEKMQEQEEKMWEQEEKM--WEQEEEDKMQEQEEMMWEQEEKM 641
Query: 558 NDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNESSRWTE 617
+++E + + K + + + + + E E Q E E E R E
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Query: 618 EEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHK 670
E+M ++ + W +M G + + + + + K++ + E L +H+
Sbjct: 702 EKMWGQEE------KMWGQEEKMWGQEEMREKEERIRDQKEK--MQERLPEHE 746
Score = 54.7 bits (130), Expect = 1e-06
Identities = 74/403 (18%), Positives = 162/403 (40%), Gaps = 54/403 (13%)
Query: 169 KEELIQNMDRV--DREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSL 226
KEE ++ +++ E E++I + +KK ++ EE + E + E + +
Sbjct: 371 KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 430
Query: 227 VQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKR 286
Q E ++K ++ E E ++ Q R E KK+ K
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQ-----EEKIWEQEEKIRDQEEM----WGQEKKMWRQEKM 481
Query: 287 RNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYE--KQFPEIRKQR 344
R + WEQ+ R DQ + W+++ E + R R KE ++RE + +Q ++R+++
Sbjct: 482 REQEDQMWEQEEKMR-DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 345 ELQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQ 404
+ QE+ + Q R E + E + E+E + ++ + +
Sbjct: 541 KTQEQEKKTWDQE------EKMREEERMREREKKMREEEEMMREQEE---------KMQE 585
Query: 405 QRIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVA 464
Q K M + + ++++ MW ++EK +E+ + + ++ E+
Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEE-KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 465 ECVLYYYLTKKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQ--------------- 509
E ++ K E + + + + +G+ ++ ++Q+++ Q Q+++
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Query: 510 ---------QPMPRSSQEEKDEKEKEKEAEKEEEKPEVENDKE 543
Q QEE EKE+ +KE+ + + +E
Sbjct: 705 WGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 42.0 bits (97), Expect = 0.008
Identities = 47/249 (18%), Positives = 105/249 (42%), Gaps = 18/249 (7%)
Query: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEK---EEEKPEVENDKEDLLKE 548
+ Q+++ ++Q+++ +Q++ + + ++++EK + EK E+EK E +KE ++
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303
Query: 549 KTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASME 608
K + + +++E + + K + + + R E E + E E
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 363
Query: 609 LNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQ 668
+E R EE M E + W +M + + + KK + +E +++
Sbjct: 364 QDERLREKEERMR-------EQEKMWEQEEKMQEEERIRE------REKKMREEEETMRE 410
Query: 669 HKLKMEK-ERNARRKKKKAPAAASEEAAFPPVVEDEEM-EASGVSGNEEEMVEEAEALHA 726
+ KM+K E N +++K + E E+M E +EE + + E +
Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 470
Query: 727 SGNEVPRGE 735
++ R E
Sbjct: 471 QEKKMWRQE 479
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 79.7 bits (195), Expect = 3e-14
Identities = 150/644 (23%), Positives = 225/644 (34%), Gaps = 116/644 (18%)
Query: 546 LKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRS-MANEANSEEAITPQQSAEL 604
+KE+ D SG+ + S+G + GR+K + + N + + + S
Sbjct: 5 VKEEDDGLSGKHSMRTRR--SRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSA 62
Query: 605 ASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDE 664
AS N+S + ET KK A+ V + S K+ KRQ
Sbjct: 63 ASTSSNDS------KAETVKKS-----------AKKVKEEASSPLKS-----NKRQ---- 96
Query: 665 ILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEAL 724
+ K+ + E R KK ++E + P + E E+S ++ ++
Sbjct: 97 ---REKVASDTEEADRTSSKKTK---TQEISRPNSPSEGEGESS-----------DSRSV 139
Query: 725 HASGNEVPRGECSGPATVNNSSDTESIPSPH-TEAAKDTGQNGP----KPPATLGADGPP 779
+ G+ P+ +N S + SIPSP E+ D+ +PPA G
Sbjct: 140 NDEGSSDPKD-----IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT 194
Query: 780 PGPPTPPPEDIPAPTE-PTPASEAT---GAPTPPPAPPSPSAPPPVVPKEEKEEETAAAP 835
P P + PP PT PTP++ A G+PT AP P AP VP ++ A P
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 254
Query: 836 --PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKA 893
P P L TG A +P + P G+ + G L
Sbjct: 255 QRPPSPHPPPHPSPHPPLQPLTGSAGQP----SAPSHAQPPLHGQGPPGPHSLQAGPLLQ 310
Query: 894 E---------KKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL 944
+ G+A S A S ++ +++ + + L P P
Sbjct: 311 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA 370
Query: 945 LTPTGDPRANASPQKPLDLKQLKQRAAAIP-PIVTKVHEPPREDAAP-----TKPAPPAP 998
+ P PQ P + P P + PP P T P A
Sbjct: 371 MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH 430
Query: 999 PPPQNLQPESDAPQQPGSSPRGKSRS---PAPPAD-------KEAEKPVFFPAFAAEAQK 1048
PPP L P+S + P G ++S P PPA + A +P F A+
Sbjct: 431 PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF-----AQHPF 485
Query: 1049 LPGDPPCWTSGLPFPVPPREVIKASP--HAPDPSAFSYAPPGH-------PLPL------ 1093
+PG PP T P P A P A P + + A G PLP
Sbjct: 486 VPGGPPPIT---PPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE 542
Query: 1094 GLHDTARPVLPRPP--TISNPPPLISSAKHPSVLERQIGAISQG 1135
L D P P PP + S P ++ + H S R + +G
Sbjct: 543 ALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 586
Score = 47.8 bits (112), Expect = 1e-04
Identities = 87/379 (22%), Positives = 132/379 (34%), Gaps = 58/379 (15%)
Query: 1802 ERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASH 1861
ERER++++E++R+RERE+ E + SS G S P
Sbjct: 627 EREREKEKEKERERERERE-----------------REAERAAKASSSAHEGRLSDPQLS 669
Query: 1862 SHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSP-VRPAATF 1920
H P P + +T + T E + P V+ T+ + P P
Sbjct: 670 GPGHMRPSFEPPPTTIAAVPPYIGPDT--PALRTLSEYARPHVMSPTNRNHPFYMPLNPT 727
Query: 1921 PP--ATHCPLGGTLDGVYPTLMEPVLLPKE-APRVARPERPRADTGHAFLAKPPARSGLE 1977
P A H P L V PT+ E L +E R R R F KPP L
Sbjct: 728 DPLLAYHMP---GLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLH 784
Query: 1978 PASSPSK--GSEPRPLVPPVSGHATIARTPAKNLAPH-HASPDPPAPPASASDPHREKTQ 2034
PA++P + +PP +G PH AS P P Q
Sbjct: 785 PAANPMEHFARHSALTIPPTAG-------------PHPFASFHPGLNPLERERLALAGPQ 831
Query: 2035 SKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELR 2094
+P L + H + +P++ + ++T P H + SH+ L
Sbjct: 832 LRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVT-----PHHHQH---SHIHSHLH 883
Query: 2095 PKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQ--HISEVITQ 2152
Q P+ G P + PL ++ P L P G L Q H E++
Sbjct: 884 LHQQDPLHQGSAGPVHPLVDPL-----TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRH 938
Query: 2153 D-YTRHHPQQLSAPLPAPL 2170
+ +P+ L +P P+
Sbjct: 939 PVFGTPYPRDLPGAIPPPM 957
Score = 43.5 bits (101), Expect = 0.003
Identities = 197/932 (21%), Positives = 300/932 (32%), Gaps = 229/932 (24%)
Query: 1405 KTQALGPLKL-KPAHEGLVATVKEAGRSIHEIPREELRHTPELPLAPRPLKEGSITQGTP 1463
K +A PLK K E + + +EA R+ + + + P P EG +
Sbjct: 83 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEG----EGESSDSRS 138
Query: 1464 LKYDTGASTTGSKKHDVRSLIGSPGRTFPPV-HPLDVMADARALERACYEESLKSRPGTA 1522
+ D G+S D RS T P + P D +D+ + + ++ L+++P
Sbjct: 139 VN-DEGSSDPKDIDQDNRS-------TSPSIPSPQDNESDS---DSSAQQQMLQAQPPAL 187
Query: 1523 SSSGG--SIARGAPVIVPELGKPRQSP--LTYEDHGAPFAGHLPRGSPVTTREPTPRL-- 1576
+ G AP P+L P +P G+P A P P P P
Sbjct: 188 QAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN-QPQAPTAPVPHTHI 246
Query: 1577 -QEGSLSSSKASQD------------RKLTSTPREIAKSPHSTVPEH------------- 1610
Q +L + + LT + + + H+ P H
Sbjct: 247 QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 306
Query: 1611 ----HPHPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPR------ 1660
HP P P+ + G + A+ TS+ A + PR
Sbjct: 307 PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366
Query: 1661 ------HLAPNPTYP---------HLYPPYLIRGYPDTAALENRQTIINDYITSQQMHHN 1705
H+ P PT P H +PP+L P + ++S HH
Sbjct: 367 APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH- 425
Query: 1706 AATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRL 1765
+A ++ P SS A P G L+Q +LP PP P T + ++
Sbjct: 426 PPSAHPPPLQLMPQSQPLPSS-----PAQPPG---LTQSQNLP---PPPASHPPTGLHQV 474
Query: 1766 AYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTST 1825
A PQP ++H P PGGP +T PT S+S
Sbjct: 475 A-----PQPPFAQH---PFVPGGPPPITPPTCPSTS------------------------ 502
Query: 1826 TTVEHAPIWRPGTEQSSGSSGSSGGGG---GSSSRP-------------ASHSHAHQHSP 1869
P PGT SG++ GG G SS P A + P
Sbjct: 503 -----TPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 557
Query: 1870 ISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLG 1929
SP + + PS H + ++ + R+ P+ G
Sbjct: 558 RSPSPEPTVVDTPS--HASQSARFYKHLDRGYNSCARTDLYFMPL-------------AG 602
Query: 1930 GTLDGVYPTLMEPVLLPKEAPRVARPERPR---------------ADTGHAFLAKPPARS 1974
L +E +EA + AR ER R + A A A
Sbjct: 603 SKLAKKREEAIEKA--KREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHE 660
Query: 1975 G------LEPASSPSKGSEPRP----LVPPVSGHATIA-RTPAKNLAPHHASP----DPP 2019
G L EP P VPP G T A RT ++ PH SP P
Sbjct: 661 GRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 720
Query: 2020 APPASASDP-----------------HRE--KTQSKPFSIQELELRSLGYHGSSYSPEGV 2060
P + +DP RE + + + I+E ELR G P +
Sbjct: 721 YMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPEL 780
Query: 2061 EPVSPVSSP--------SLTHDKGLPKH--------LEELDKSHLE---GELRPKQPGPV 2101
+P+ P ++P +LT H L L++ L +LRP+ P
Sbjct: 781 DPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPD 840
Query: 2102 KLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVT-LAQHISEVITQDYTRH-HP 2159
+L E H + L + + P H + + L H + + Q HP
Sbjct: 841 RLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHP 900
Query: 2160 --QQLSAPLPAPLYSFPGASCPVLDLRRPPSD 2189
L+A + +P + P L +PP +
Sbjct: 901 LVDPLTAGPHLARFPYPPGTLPNPLLGQPPHE 932
Score = 39.7 bits (91), Expect = 0.038
Identities = 73/314 (23%), Positives = 107/314 (34%), Gaps = 36/314 (11%)
Query: 1969 KPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDP 2028
K A+ E ASSP K S R S RT +K S P S S+
Sbjct: 76 KKSAKKVKEEASSPLK-SNKRQREKVASDTEEADRTSSKKTKTQEISR-----PNSPSEG 129
Query: 2029 HREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSH 2088
E + S RS+ GSS P+ ++ + +SPS+ P+ E S
Sbjct: 130 EGESSDS----------RSVNDEGSS-DPKDIDQDNRSTSPSIPS----PQDNESDSDSS 174
Query: 2089 LEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISE 2148
+ ++ QP ++ + P P S P +P L T V
Sbjct: 175 AQQQMLQAQPPALQAP------TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP--- 225
Query: 2149 VITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSE 2208
T + PQ +AP+P P L +RPPS P P P + S
Sbjct: 226 --TASQAPNQPQAPTAPVPHTHIQ----QAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 279
Query: 2209 GGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKS 2268
G +P + + G G G + + PG + P G+ + +
Sbjct: 280 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 339
Query: 2269 PGNTSQPPAFFSKL 2282
P + Q PA S L
Sbjct: 340 PHTSLQLPASQSAL 353
Score = 32.0 bits (71), Expect = 7.9
Identities = 12/45 (26%), Positives = 28/45 (62%)
Query: 491 GKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEK 535
G +++++ ++ +++ + R +E + EKEKE+E E+E E+
Sbjct: 602 GSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 646
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 78.2 bits (191), Expect = 1e-13
Identities = 100/378 (26%), Positives = 136/378 (35%), Gaps = 78/378 (20%)
Query: 778 PPPGPPTPPPEDIPAPT--EPTPASEATGAPTPP-----PAPPSPSAPPPVVPKEEKEEE 830
PPPGP PP+DI P P P+ +T P PP P PPS + PPP V +
Sbjct: 142 PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201
Query: 831 TAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGA 890
T ++P + + PPA P + PA A A+ T
Sbjct: 202 TLSSPSIPTPPDFIPPA-------------PPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248
Query: 891 LKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGD 950
L G T KS A + AT ++ AE +P P L P
Sbjct: 249 LFP------PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRS- 301
Query: 951 PRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQ----- 1005
P P+ R ++IP V + E PR++ TK AP P P +
Sbjct: 302 --FKVPPPTPV-------RTSSIP--VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
Query: 1006 -------PESDAPQQ-----PGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDP 1053
PE D P + P S G+S+S AD+ A P P A LP
Sbjct: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQS---QADERAGTPPPAPPLPPPAPPLPPPA 407
Query: 1054 PCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPP 1113
P LP PP + + H P+ F+ P ++ P L P +P
Sbjct: 408 P----PLPPAAPPLPCAQKAAH--PPAGFTKTP----------KSSSPALKPKPNPPSPE 451
Query: 1114 PLISSA----KHPSVLER 1127
SSA + PS +E+
Sbjct: 452 NTASSAPVDWRDPSQMEK 469
Score = 68.6 bits (166), Expect = 8e-11
Identities = 97/342 (28%), Positives = 129/342 (37%), Gaps = 55/342 (16%)
Query: 732 PRGECSGPAT-VNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDI 790
P G GP ++ +PSP + A P PP L PPP PPP +
Sbjct: 143 PPGPAPGPPQDISEPPGGSPLPSPPSTA--------PPPPPLLLEPPPPPSMAPPPPPVL 194
Query: 791 PAPTEPTPASEATGAPTP----PPAPPSP--SAPPPVVPKEEKEEETAAAPPVEEGEEQK 844
A + P S + PTP PPAPP + PPP VP A A P G
Sbjct: 195 EALSPPHTLS-SPSIPTPPDFIPPAPPLAFLAPPPPPVP---APAPPAPASPHTVGTRLF 250
Query: 845 PPAA-----EELAVDTGKAEEPVKSECTEEAE-EGPAKGKDAEAAEATAEGALKAEKKEG 898
PP ++A++ +AE S AE +G A G + E T + K
Sbjct: 251 PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE-PHLTFPRSFKVPP--- 306
Query: 899 GSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDK---NRLLSPRPSLLTPTGDPRANA 955
T ++S P A + EG K +RL P + P +
Sbjct: 307 ----PTPVRTSSIPVQEAQEAP------RKEEGATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 956 SPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPG 1015
+P+ P +LK A A P + + E A PAPP PPP L P AP P
Sbjct: 357 APE-PDCPGELKATAPASPRL-GQSQSQADERAGTPPPAPPLPPPAPPLPP--PAPPLPP 412
Query: 1016 SSPRGKSRSPAPPADKEAEKPVFF---PAFAAEAQKLPGDPP 1054
++P P P A K A P F P ++ A K +PP
Sbjct: 413 AAP------PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP 448
Score = 54.3 bits (129), Expect = 1e-06
Identities = 93/382 (24%), Positives = 139/382 (36%), Gaps = 36/382 (9%)
Query: 727 SGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNG-PKPPATLGADGPPPGPPT- 784
SG P SGPA + ++ + S A KD+G G P+ PA+ P
Sbjct: 677 SGPTTPLKATSGPAIASTATTLPTTTS-QLMAEKDSGPAGQPEKPASQEVSTPSQARGEG 735
Query: 785 PPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAA-PPVEEGEEQ 843
P E PT+ +S A T P P P + E A P + G
Sbjct: 736 SPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAA 795
Query: 844 KPPAAEELAVDTG-KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEG-ALKAEKKEGGSG 901
P E+ G A+ P ++ T+E P G+ E A A + ++G S
Sbjct: 796 GPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSV 855
Query: 902 RATTAKSS--GAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQK 959
A +SS G+ +D A S+D + ++G + + P+ P P K
Sbjct: 856 GAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNK 915
Query: 960 --PLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSS 1017
P +L + A +++ H TKP P AP + + P S+ P Q
Sbjct: 916 WGP----RLGRDAEGTE--LSRRHNW-------TKPEPQAPVAWERVAP-SNLP-QGHPL 960
Query: 1018 PRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPF----PVPP------- 1066
P+ S P+P +E E+ F + DP L + PP
Sbjct: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
Query: 1067 REVIKASPHAPDPSAFSYAPPG 1088
R++ A P AP FS P G
Sbjct: 1021 RQLPNAGPGAPPALGFSRFPAG 1042
Score = 53.5 bits (127), Expect = 3e-06
Identities = 138/591 (23%), Positives = 196/591 (33%), Gaps = 98/591 (16%)
Query: 729 NEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPE 788
+ P +C G + + ++A + G P PP A PP PP PP
Sbjct: 355 DRAPEPDCPGELKATAPASPR-LGQSQSQADERAGTPPPAPPLPPPA---PPLPPPAPP- 409
Query: 789 DIPAPTEPTPASEATGAP----TPPPAPPSPSAPPPVVPKEEKEEETAAAPPVE-EGEEQ 843
+P P P ++ P T P SP+ P P E TA++ PV+ Q
Sbjct: 410 -LPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPK--PNPPSPENTASSAPVDWRDPSQ 466
Query: 844 KPPAAEELAVD-TGKAEE---------PVKSECTEEAEEGPAKGKDAEAAEATAEGALKA 893
ELA G E P + ++E ++GP + A+
Sbjct: 467 MEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG 526
Query: 894 --EKKEGGSGRATTAKSSG--------APQDSDSSAT--------CSADEVDEAEGGDKN 935
EK GGS T + PQDS + + E E
Sbjct: 527 VPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSI 586
Query: 936 RLLSPRPSL----LTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPT 991
L P+P L + G S KP+ K L ++ + P + + A P
Sbjct: 587 GSLPPKPRLEGGRICENGADDDKLS--KPV-AKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643
Query: 992 KPAP-PAPPPPQNLQPESDAPQQPG-SSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL 1049
K P PA PP L P + G ++P + P P K PA A+ A L
Sbjct: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPL-----KATSGPAIASTATTL 698
Query: 1050 P-------GDPPCWTSGLPFPVPPREVIKASPHAPD--PSAFSYAPPGHPLPLGLHDTAR 1100
P + +G P +EV S + PS + P G +A
Sbjct: 699 PTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLP-----TQGARSSAA 753
Query: 1101 PVLPRPPTISNPPPLISSAKHPSVLERQI----------GAISQGMSVQLHVPYSEHAKA 1150
P P L H S L R++ GA G V++ P AK
Sbjct: 754 FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKP 813
Query: 1151 PVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSV 1210
P P D P +G E+ G P +L + Q A +G ++G+
Sbjct: 814 PAS------AQPTDELLRHPVTGEVVER-------GSPMALLLAARQRAQ--KGRSVGAA 858
Query: 1211 PGGSITKGIPSTRVPSDSAITYRGSITH--GTPADVLYKGTITRIIGEDSP 1259
G S G S R S A SI H GTP + + +DSP
Sbjct: 859 LGRSSLPG--SLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSP 907
Score = 42.0 bits (97), Expect = 0.008
Identities = 66/267 (24%), Positives = 83/267 (31%), Gaps = 26/267 (9%)
Query: 937 LLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPP 996
LL P P G P+ + P L A PP++ + PP A P P
Sbjct: 137 LLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE-PPPPPSMAPPPPPVLE 195
Query: 997 APPPPQNL-QPESDAPQQ--PGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDP 1053
A PP L P P P + P P PP A P PG
Sbjct: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGV 255
Query: 1054 PCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPP 1113
W S + E +ASP P P L P L P + PP
Sbjct: 256 TKWKSDVALNGRQAEATRASPP---------RSPAEPKGSALGPNPEPHLTFPRSFKVPP 306
Query: 1114 PLISSAKHPSVLE------RQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKK 1167
P V E ++ GA + S +L +P S H + P P P +
Sbjct: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPS-RLPLPPSFHIRPASQVYPDRAPEPDCPGE 365
Query: 1168 L------APFSGVKQEQLSPRGQAGPP 1188
L +P G Q Q R PP
Sbjct: 366 LKATAPASPRLGQSQSQADERAGTPPP 392
Score = 42.0 bits (97), Expect = 0.008
Identities = 129/575 (22%), Positives = 192/575 (33%), Gaps = 138/575 (24%)
Query: 1049 LPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT 1108
+P PP P P PP+++ + +P PS S APP PL L P P PP+
Sbjct: 139 IPPPPPG-----PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLL------EP--PPPPS 185
Query: 1109 ISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLP-LPMDPKK 1167
++ PPP + A P P T+ P +P P
Sbjct: 186 MAPPPPPVLEALSP-------------------------------PHTLSSPSIPTPPDF 214
Query: 1168 LAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSD 1227
+ P L+ PP P A + GT L P G +TK SD
Sbjct: 215 IPP-----APPLAFLAPPPPPVPAPAPPAPASPHTVGTRL--FPPGGVTKW------KSD 261
Query: 1228 SAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEGKKGHVLSY 1287
A+ R + +R R + PKG + + H L++
Sbjct: 262 VALNGR----------------------QAEATRASPPRSPAEPKGSALGPNPEPH-LTF 298
Query: 1288 EGGMSVTQCSKEDGRSSSGPPHETA-APKRTYDMMEGRVGRAISSASIEGLMGRAIPPER 1346
V + R+SS P E AP++ + R S + P+R
Sbjct: 299 PRSFKVPPPTPV--RTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 1347 HSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPP-----------PP 1395
+ + + +S +A E R GTPPP PP
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADE-----------RAGTPPPAPPLPPPAPPLPP 405
Query: 1396 PSRDLTEAYKTQALGPLKLKPAH--EGLVATVKEAGRSIHEIPREELRHTPELPLAPRPL 1453
P+ L A P K AH G T K + ++ P +PE + P+
Sbjct: 406 PAPPLPPAAPPL---PCAQKAAHPPAGFTKTPKSSSPALKPKPNPP---SPENTASSAPV 459
Query: 1454 KEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADARALERACYEE 1513
+Q L+ + A GS++ D R L PG T P + + R +E
Sbjct: 460 DWRDPSQMEKLRNELAAYLCGSRRED-RFLSHRPGPTVAP-----QSKEGKKGPRLPEKE 513
Query: 1514 SLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTTREPT 1573
+L S P A+ P VPE K E AP + LP + PT
Sbjct: 514 TLLSLP----------AKDTPPGVPE--KSLGGSSLTETEAAP-SLTLPSVDYIPQDSPT 560
Query: 1574 PRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVP 1608
P S+ + + +L+S + AK ++P
Sbjct: 561 P-----SVRQIRNELEARLSSAAEKEAKPSIGSLP 590
Score = 42.0 bits (97), Expect = 0.008
Identities = 72/291 (24%), Positives = 100/291 (34%), Gaps = 49/291 (16%)
Query: 1968 AKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIA-------------RTPAKNLAPHHA 2014
A PP LEP PS P P++ +S T++ P LAP
Sbjct: 170 APPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPP 229
Query: 2015 SPDPPAPPASASDPHREKTQSKP------------FSIQELELRSLGYHGSSYSPEGVEP 2062
PAPPA AS PH T+ P + ++ E S P+G
Sbjct: 230 PVPAPAPPAPAS-PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKG-SA 287
Query: 2063 VSPVSSPSLTHDKGL----PKHLEELDKSHLEGELRP-KQPGPVKLGGEAAHLP---HLR 2114
+ P P LT + P + E + P K+ G K LP H+R
Sbjct: 288 LGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIR 347
Query: 2115 PLPESQPSSSPLLQTAPGVKGHQRVVTLAQ-HISEVITQDYTRHHPQQLSAPLPAPLYSF 2173
P + P +P P G + A + + +Q R + PLP P
Sbjct: 348 PASQVYPDRAP----EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPL 403
Query: 2174 PGASCPVLDLRRPPSDLYLPPPDHGA-PARG---SPHSEGGKRSPEPNKTS 2220
P + P+ PP+ LP A P G +P S P+PN S
Sbjct: 404 PPPAPPL-----PPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPS 449
Score = 35.8 bits (81), Expect = 0.55
Identities = 70/306 (22%), Positives = 100/306 (32%), Gaps = 54/306 (17%)
Query: 2159 PQQLSAP-LPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPN 2217
P LS+P +P P P A P+ L PP + P P PA SPH+ G + P
Sbjct: 200 PHTLSSPSIPTPPDFIPPAP-PLAFLAPPPPPVPAPAP----PAPASPHTVGTRLFPPGG 254
Query: 2218 KTS-----VLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNT 2272
T L G + SPP EP S G EP +S
Sbjct: 255 VTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL---------GPNPEPHLTFPRSFKVP 305
Query: 2273 SQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLM 2332
P S + + K++ KK + P ++I +P +++
Sbjct: 306 PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RPASQV------------ 352
Query: 2333 TYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEE-------SPPLSANAFNPLNASASLP 2385
Y +A + + A L Q +E +PPL A + LP
Sbjct: 353 -YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLP 411
Query: 2386 AAMPITAADGRSDHTLTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGD 2445
A P ++ H P G K KS +P L PPS + S
Sbjct: 412 PAAPPLPCAQKAAHP---PAGFTKTP----------KSSSPALKPKPNPPSPENTASSAP 458
Query: 2446 CNRRTP 2451
+ R P
Sbjct: 459 VDWRDP 464
Score = 35.0 bits (79), Expect = 0.94
Identities = 64/248 (25%), Positives = 83/248 (33%), Gaps = 35/248 (14%)
Query: 1897 VEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPE 1956
V P TP ++S PV+ A P G T + P + A +V
Sbjct: 304 VPPPTPV----RTSSIPVQEAQEAPRKEE---GATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 1957 RPRADTGHAFLAKPPA--RSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHA 2014
P D A PA R G + + + P P PP+ PA L P
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADERAGTPPP-APPLP-------PPAPPLPP--- 405
Query: 2015 SPDPPAPPASASDPHREKTQSKPFSIQELELRS---LGYHGSSYSPEGVEPVSPVSSPSL 2071
P PP PPA+ P +K P + S L + SPE +PV
Sbjct: 406 -PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464
Query: 2072 THDKGLPKHLEE-LDKSHLEGELRPKQPGPV-----KLGGEAAHLPHLRPLPESQPSSSP 2125
+ + L L L S E +PGP K G + LP L S P
Sbjct: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL-----LSLP 519
Query: 2126 LLQTAPGV 2133
T PGV
Sbjct: 520 AKDTPPGV 527
Score = 32.7 bits (73), Expect = 4.6
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 17/135 (12%)
Query: 784 TPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEET----AAAPPVEE 839
T P P E S P P P S S+PP K E+EEE PP E
Sbjct: 936 TKPEPQAPVAWERVAPSNL---PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEF 992
Query: 840 GEEQKPPAAEELAVDTGKAEEPVKSECTE-----EAEEG--PAKGKDAEAAEATAEGALK 892
+ +PPA + G+ P ++ ++ A G PA G A A GA
Sbjct: 993 SNDPEPPAPALQYL--GRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGG 1050
Query: 893 AEKKEGGSGRATTAK 907
E+ GG GR+ K
Sbjct: 1051 LERFSGG-GRSLIKK 1064
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 78.2 bits (191), Expect = 1e-13
Identities = 100/378 (26%), Positives = 136/378 (35%), Gaps = 78/378 (20%)
Query: 778 PPPGPPTPPPEDIPAPT--EPTPASEATGAPTPP-----PAPPSPSAPPPVVPKEEKEEE 830
PPPGP PP+DI P P P+ +T P PP P PPS + PPP V +
Sbjct: 142 PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201
Query: 831 TAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGA 890
T ++P + + PPA P + PA A A+ T
Sbjct: 202 TLSSPSIPTPPDFIPPA-------------PPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248
Query: 891 LKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGD 950
L G T KS A + AT ++ AE +P P L P
Sbjct: 249 LFP------PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRS- 301
Query: 951 PRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQ----- 1005
P P+ R ++IP V + E PR++ TK AP P P +
Sbjct: 302 --FKVPPPTPV-------RTSSIP--VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
Query: 1006 -------PESDAPQQ-----PGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDP 1053
PE D P + P S G+S+S AD+ A P P A LP
Sbjct: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQS---QADERAGTPPPAPPLPPPAPPLPPPA 407
Query: 1054 PCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPP 1113
P LP PP + + H P+ F+ P ++ P L P +P
Sbjct: 408 P----PLPPAAPPLPCAQKAAH--PPAGFTKTP----------KSSSPALKPKPNPPSPE 451
Query: 1114 PLISSA----KHPSVLER 1127
SSA + PS +E+
Sbjct: 452 NTASSAPVDWRDPSQMEK 469
Score = 68.6 bits (166), Expect = 8e-11
Identities = 97/342 (28%), Positives = 129/342 (37%), Gaps = 55/342 (16%)
Query: 732 PRGECSGPAT-VNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDI 790
P G GP ++ +PSP + A P PP L PPP PPP +
Sbjct: 143 PPGPAPGPPQDISEPPGGSPLPSPPSTA--------PPPPPLLLEPPPPPSMAPPPPPVL 194
Query: 791 PAPTEPTPASEATGAPTP----PPAPPSP--SAPPPVVPKEEKEEETAAAPPVEEGEEQK 844
A + P S + PTP PPAPP + PPP VP A A P G
Sbjct: 195 EALSPPHTLS-SPSIPTPPDFIPPAPPLAFLAPPPPPVP---APAPPAPASPHTVGTRLF 250
Query: 845 PPAA-----EELAVDTGKAEEPVKSECTEEAE-EGPAKGKDAEAAEATAEGALKAEKKEG 898
PP ++A++ +AE S AE +G A G + E T + K
Sbjct: 251 PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE-PHLTFPRSFKVPP--- 306
Query: 899 GSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDK---NRLLSPRPSLLTPTGDPRANA 955
T ++S P A + EG K +RL P + P +
Sbjct: 307 ----PTPVRTSSIPVQEAQEAP------RKEEGATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 956 SPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPG 1015
+P+ P +LK A A P + + E A PAPP PPP L P AP P
Sbjct: 357 APE-PDCPGELKATAPASPRL-GQSQSQADERAGTPPPAPPLPPPAPPLPP--PAPPLPP 412
Query: 1016 SSPRGKSRSPAPPADKEAEKPVFF---PAFAAEAQKLPGDPP 1054
++P P P A K A P F P ++ A K +PP
Sbjct: 413 AAP------PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP 448
Score = 54.3 bits (129), Expect = 1e-06
Identities = 93/382 (24%), Positives = 139/382 (36%), Gaps = 36/382 (9%)
Query: 727 SGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNG-PKPPATLGADGPPPGPPT- 784
SG P SGPA + ++ + S A KD+G G P+ PA+ P
Sbjct: 677 SGPTTPLKATSGPAIASTATTLPTTTS-QLMAEKDSGPAGQPEKPASQEVSTPSQARGEG 735
Query: 785 PPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAA-PPVEEGEEQ 843
P E PT+ +S A T P P P + E A P + G
Sbjct: 736 SPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAA 795
Query: 844 KPPAAEELAVDTG-KAEEPVKSECTEEAEEGPAKGKDAEAAEATAEG-ALKAEKKEGGSG 901
P E+ G A+ P ++ T+E P G+ E A A + ++G S
Sbjct: 796 GPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSV 855
Query: 902 RATTAKSS--GAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQK 959
A +SS G+ +D A S+D + ++G + + P+ P P K
Sbjct: 856 GAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNK 915
Query: 960 --PLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSS 1017
P +L + A +++ H TKP P AP + + P S+ P Q
Sbjct: 916 WGP----RLGRDAEGTE--LSRRHNW-------TKPEPQAPVAWERVAP-SNLP-QGHPL 960
Query: 1018 PRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPF----PVPP------- 1066
P+ S P+P +E E+ F + DP L + PP
Sbjct: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
Query: 1067 REVIKASPHAPDPSAFSYAPPG 1088
R++ A P AP FS P G
Sbjct: 1021 RQLPNAGPGAPPALGFSRFPAG 1042
Score = 53.5 bits (127), Expect = 3e-06
Identities = 138/591 (23%), Positives = 196/591 (33%), Gaps = 98/591 (16%)
Query: 729 NEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPE 788
+ P +C G + + ++A + G P PP A PP PP PP
Sbjct: 355 DRAPEPDCPGELKATAPASPR-LGQSQSQADERAGTPPPAPPLPPPA---PPLPPPAPP- 409
Query: 789 DIPAPTEPTPASEATGAP----TPPPAPPSPSAPPPVVPKEEKEEETAAAPPVE-EGEEQ 843
+P P P ++ P T P SP+ P P E TA++ PV+ Q
Sbjct: 410 -LPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPK--PNPPSPENTASSAPVDWRDPSQ 466
Query: 844 KPPAAEELAVD-TGKAEE---------PVKSECTEEAEEGPAKGKDAEAAEATAEGALKA 893
ELA G E P + ++E ++GP + A+
Sbjct: 467 MEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG 526
Query: 894 --EKKEGGSGRATTAKSSG--------APQDSDSSAT--------CSADEVDEAEGGDKN 935
EK GGS T + PQDS + + E E
Sbjct: 527 VPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSI 586
Query: 936 RLLSPRPSL----LTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPT 991
L P+P L + G S KP+ K L ++ + P + + A P
Sbjct: 587 GSLPPKPRLEGGRICENGADDDKLS--KPV-AKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643
Query: 992 KPAP-PAPPPPQNLQPESDAPQQPG-SSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL 1049
K P PA PP L P + G ++P + P P K PA A+ A L
Sbjct: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPL-----KATSGPAIASTATTL 698
Query: 1050 P-------GDPPCWTSGLPFPVPPREVIKASPHAPD--PSAFSYAPPGHPLPLGLHDTAR 1100
P + +G P +EV S + PS + P G +A
Sbjct: 699 PTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLP-----TQGARSSAA 753
Query: 1101 PVLPRPPTISNPPPLISSAKHPSVLERQI----------GAISQGMSVQLHVPYSEHAKA 1150
P P L H S L R++ GA G V++ P AK
Sbjct: 754 FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKP 813
Query: 1151 PVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSV 1210
P P D P +G E+ G P +L + Q A +G ++G+
Sbjct: 814 PAS------AQPTDELLRHPVTGEVVER-------GSPMALLLAARQRAQ--KGRSVGAA 858
Query: 1211 PGGSITKGIPSTRVPSDSAITYRGSITH--GTPADVLYKGTITRIIGEDSP 1259
G S G S R S A SI H GTP + + +DSP
Sbjct: 859 LGRSSLPG--SLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSP 907
Score = 42.0 bits (97), Expect = 0.008
Identities = 66/267 (24%), Positives = 83/267 (31%), Gaps = 26/267 (9%)
Query: 937 LLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPP 996
LL P P G P+ + P L A PP++ + PP A P P
Sbjct: 137 LLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE-PPPPPSMAPPPPPVLE 195
Query: 997 APPPPQNL-QPESDAPQQ--PGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDP 1053
A PP L P P P + P P PP A P PG
Sbjct: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGV 255
Query: 1054 PCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPP 1113
W S + E +ASP P P L P L P + PP
Sbjct: 256 TKWKSDVALNGRQAEATRASPP---------RSPAEPKGSALGPNPEPHLTFPRSFKVPP 306
Query: 1114 PLISSAKHPSVLE------RQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKK 1167
P V E ++ GA + S +L +P S H + P P P +
Sbjct: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPS-RLPLPPSFHIRPASQVYPDRAPEPDCPGE 365
Query: 1168 L------APFSGVKQEQLSPRGQAGPP 1188
L +P G Q Q R PP
Sbjct: 366 LKATAPASPRLGQSQSQADERAGTPPP 392
Score = 42.0 bits (97), Expect = 0.008
Identities = 129/575 (22%), Positives = 192/575 (33%), Gaps = 138/575 (24%)
Query: 1049 LPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT 1108
+P PP P P PP+++ + +P PS S APP PL L P P PP+
Sbjct: 139 IPPPPPG-----PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLL------EP--PPPPS 185
Query: 1109 ISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLP-LPMDPKK 1167
++ PPP + A P P T+ P +P P
Sbjct: 186 MAPPPPPVLEALSP-------------------------------PHTLSSPSIPTPPDF 214
Query: 1168 LAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTRVPSD 1227
+ P L+ PP P A + GT L P G +TK SD
Sbjct: 215 IPP-----APPLAFLAPPPPPVPAPAPPAPASPHTVGTRL--FPPGGVTKW------KSD 261
Query: 1228 SAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDSLPKGHVIYEGKKGHVLSY 1287
A+ R + +R R + PKG + + H L++
Sbjct: 262 VALNGR----------------------QAEATRASPPRSPAEPKGSALGPNPEPH-LTF 298
Query: 1288 EGGMSVTQCSKEDGRSSSGPPHETA-APKRTYDMMEGRVGRAISSASIEGLMGRAIPPER 1346
V + R+SS P E AP++ + R S + P+R
Sbjct: 299 PRSFKVPPPTPV--RTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 1347 HSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREGTPPP-----------PP 1395
+ + + +S +A E R GTPPP PP
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADE-----------RAGTPPPAPPLPPPAPPLPP 405
Query: 1396 PSRDLTEAYKTQALGPLKLKPAH--EGLVATVKEAGRSIHEIPREELRHTPELPLAPRPL 1453
P+ L A P K AH G T K + ++ P +PE + P+
Sbjct: 406 PAPPLPPAAPPL---PCAQKAAHPPAGFTKTPKSSSPALKPKPNPP---SPENTASSAPV 459
Query: 1454 KEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADARALERACYEE 1513
+Q L+ + A GS++ D R L PG T P + + R +E
Sbjct: 460 DWRDPSQMEKLRNELAAYLCGSRRED-RFLSHRPGPTVAP-----QSKEGKKGPRLPEKE 513
Query: 1514 SLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTTREPT 1573
+L S P A+ P VPE K E AP + LP + PT
Sbjct: 514 TLLSLP----------AKDTPPGVPE--KSLGGSSLTETEAAP-SLTLPSVDYIPQDSPT 560
Query: 1574 PRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVP 1608
P S+ + + +L+S + AK ++P
Sbjct: 561 P-----SVRQIRNELEARLSSAAEKEAKPSIGSLP 590
Score = 42.0 bits (97), Expect = 0.008
Identities = 72/291 (24%), Positives = 100/291 (34%), Gaps = 49/291 (16%)
Query: 1968 AKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIA-------------RTPAKNLAPHHA 2014
A PP LEP PS P P++ +S T++ P LAP
Sbjct: 170 APPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPP 229
Query: 2015 SPDPPAPPASASDPHREKTQSKP------------FSIQELELRSLGYHGSSYSPEGVEP 2062
PAPPA AS PH T+ P + ++ E S P+G
Sbjct: 230 PVPAPAPPAPAS-PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKG-SA 287
Query: 2063 VSPVSSPSLTHDKGL----PKHLEELDKSHLEGELRP-KQPGPVKLGGEAAHLP---HLR 2114
+ P P LT + P + E + P K+ G K LP H+R
Sbjct: 288 LGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIR 347
Query: 2115 PLPESQPSSSPLLQTAPGVKGHQRVVTLAQ-HISEVITQDYTRHHPQQLSAPLPAPLYSF 2173
P + P +P P G + A + + +Q R + PLP P
Sbjct: 348 PASQVYPDRAP----EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPL 403
Query: 2174 PGASCPVLDLRRPPSDLYLPPPDHGA-PARG---SPHSEGGKRSPEPNKTS 2220
P + P+ PP+ LP A P G +P S P+PN S
Sbjct: 404 PPPAPPL-----PPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPS 449
Score = 35.8 bits (81), Expect = 0.55
Identities = 70/306 (22%), Positives = 100/306 (32%), Gaps = 54/306 (17%)
Query: 2159 PQQLSAP-LPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPN 2217
P LS+P +P P P A P+ L PP + P P PA SPH+ G + P
Sbjct: 200 PHTLSSPSIPTPPDFIPPAP-PLAFLAPPPPPVPAPAP----PAPASPHTVGTRLFPPGG 254
Query: 2218 KTS-----VLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNT 2272
T L G + SPP EP S G EP +S
Sbjct: 255 VTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL---------GPNPEPHLTFPRSFKVP 305
Query: 2273 SQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLM 2332
P S + + K++ KK + P ++I +P +++
Sbjct: 306 PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RPASQV------------ 352
Query: 2333 TYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEE-------SPPLSANAFNPLNASASLP 2385
Y +A + + A L Q +E +PPL A + LP
Sbjct: 353 -YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLP 411
Query: 2386 AAMPITAADGRSDHTLTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGD 2445
A P ++ H P G K KS +P L PPS + S
Sbjct: 412 PAAPPLPCAQKAAHP---PAGFTKTP----------KSSSPALKPKPNPPSPENTASSAP 458
Query: 2446 CNRRTP 2451
+ R P
Sbjct: 459 VDWRDP 464
Score = 35.0 bits (79), Expect = 0.94
Identities = 64/248 (25%), Positives = 83/248 (33%), Gaps = 35/248 (14%)
Query: 1897 VEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPE 1956
V P TP ++S PV+ A P G T + P + A +V
Sbjct: 304 VPPPTPV----RTSSIPVQEAQEAPRKEE---GATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 1957 RPRADTGHAFLAKPPA--RSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHA 2014
P D A PA R G + + + P P PP+ PA L P
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADERAGTPPP-APPLP-------PPAPPLPP--- 405
Query: 2015 SPDPPAPPASASDPHREKTQSKPFSIQELELRS---LGYHGSSYSPEGVEPVSPVSSPSL 2071
P PP PPA+ P +K P + S L + SPE +PV
Sbjct: 406 -PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464
Query: 2072 THDKGLPKHLEE-LDKSHLEGELRPKQPGPV-----KLGGEAAHLPHLRPLPESQPSSSP 2125
+ + L L L S E +PGP K G + LP L S P
Sbjct: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL-----LSLP 519
Query: 2126 LLQTAPGV 2133
T PGV
Sbjct: 520 AKDTPPGV 527
Score = 32.7 bits (73), Expect = 4.6
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 17/135 (12%)
Query: 784 TPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEET----AAAPPVEE 839
T P P E S P P P S S+PP K E+EEE PP E
Sbjct: 936 TKPEPQAPVAWERVAPSNL---PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEF 992
Query: 840 GEEQKPPAAEELAVDTGKAEEPVKSECTE-----EAEEG--PAKGKDAEAAEATAEGALK 892
+ +PPA + G+ P ++ ++ A G PA G A A GA
Sbjct: 993 SNDPEPPAPALQYL--GRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGG 1050
Query: 893 AEKKEGGSGRATTAK 907
E+ GG GR+ K
Sbjct: 1051 LERFSGG-GRSLIKK 1064
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 130,675,936
Number of Sequences: 37866
Number of extensions: 8678036
Number of successful extensions: 166108
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1376
Number of HSP's successfully gapped in prelim test: 2888
Number of HSP's that attempted gapping in prelim test: 48003
Number of HSP's gapped (non-prelim): 61845
length of query: 2524
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2405
effective length of database: 13,741,464
effective search space: 33048220920
effective search space used: 33048220920
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.