Guide to the Human Genome
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Search of human proteins with 116235460

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116235460 YTH domain family, member 3 [Homo sapiens]
         (585 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116235460 YTH domain family, member 3 [Homo sapiens]              1212   0.0  
gi|116812575 high glucose-regulated protein 8 [Homo sapiens]          797   0.0  
gi|31377750 YTH domain family, member 1 [Homo sapiens]                790   0.0  
gi|38505213 YTH domain containing 2 [Homo sapiens]                     67   3e-11
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           66   8e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    65   2e-10
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           65   2e-10
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    59   1e-08
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    59   1e-08
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    59   1e-08
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              59   1e-08
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    55   2e-07
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    55   2e-07
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    55   2e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     55   2e-07
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    54   3e-07
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    54   3e-07
gi|190343021 Sec24-related protein D [Homo sapiens]                    54   3e-07
gi|38261971 cyclic AMP-regulated phosphoprotein, 21 kD isoform 1...    54   4e-07
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       54   5e-07
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     52   1e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     52   1e-06
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     52   1e-06
gi|162951884 R3H domain containing 2 [Homo sapiens]                    52   2e-06
gi|114431236 zinc finger protein 462 [Homo sapiens]                    51   3e-06
gi|83977459 pleckstrin homology-like domain, family A, member 1 ...    51   3e-06
gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]         51   3e-06
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    50   6e-06
gi|31543535 R3H domain containing 1 [Homo sapiens]                     49   1e-05
gi|55741675 hypothetical protein LOC22889 [Homo sapiens]               49   1e-05

>gi|116235460 YTH domain family, member 3 [Homo sapiens]
          Length = 585

 Score = 1212 bits (3135), Expect = 0.0
 Identities = 585/585 (100%), Positives = 585/585 (100%)

Query: 1   MSATSVDQRPKGQGNKVSVQNGSIHQKDAVNDDDFEPYLSSQTNQSNSYPPMSDPYMPSY 60
           MSATSVDQRPKGQGNKVSVQNGSIHQKDAVNDDDFEPYLSSQTNQSNSYPPMSDPYMPSY
Sbjct: 1   MSATSVDQRPKGQGNKVSVQNGSIHQKDAVNDDDFEPYLSSQTNQSNSYPPMSDPYMPSY 60

Query: 61  YAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLG 120
           YAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLG
Sbjct: 61  YAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLG 120

Query: 121 QHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSK 180
           QHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSK
Sbjct: 121 QHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSK 180

Query: 181 VPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAA 240
           VPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAA
Sbjct: 181 VPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAA 240

Query: 241 IARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTI 300
           IARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTI
Sbjct: 241 IARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTI 300

Query: 301 IQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNR 360
           IQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNR
Sbjct: 301 IQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNR 360

Query: 361 GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDWNLKNGRVFI 420
           GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDWNLKNGRVFI
Sbjct: 361 GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDWNLKNGRVFI 420

Query: 421 IKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGHFCGVAEMK 480
           IKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGHFCGVAEMK
Sbjct: 421 IKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGHFCGVAEMK 480

Query: 481 SVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPL 540
           SVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPL
Sbjct: 481 SVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPL 540

Query: 541 EKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRERNRNKQ 585
           EKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRERNRNKQ
Sbjct: 541 EKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRERNRNKQ 585


>gi|116812575 high glucose-regulated protein 8 [Homo sapiens]
          Length = 579

 Score =  797 bits (2059), Expect = 0.0
 Identities = 405/598 (67%), Positives = 468/598 (78%), Gaps = 42/598 (7%)

Query: 1   MSATSV-DQRPKGQGNKVSVQNGSIHQKDAVNDDDFEPYLSSQTNQSNSYPPMSDPYMPS 59
           MSA+S+ +QRPKGQGNKV  QNGS+HQKD +NDDDFEPYLS Q   +N+Y  MSD Y+PS
Sbjct: 1   MSASSLLEQRPKGQGNKV--QNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPS 58

Query: 60  YYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFL 119
           YY+PSIGF YSLGEAAWST GD  MPYLT+YGQ+SNGE H++PD +F QPGALG+TP FL
Sbjct: 59  YYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTP-FL 117

Query: 120 GQHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLS 179
           GQHGFNFFP   DFS WG + SQGQSTQSS YSS+Y Y PSSLG A+ DGQ+ F N+TL+
Sbjct: 118 GQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLN 177

Query: 180 KVPGISSIEQGMTGLKIGG-DLTAAVTKTVGTALSSSGMTS--IATNSVPPVSSAAPKPT 236
           K PG+++I+QGM  LK+G  ++ + V K VG+A+ S  +TS  +A+NS+PP + A PKP 
Sbjct: 178 KAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPA 237

Query: 237 SWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLP 296
           SWA IA KPAK QPKLK K   GI GS++PPPPIKHNM+IGTWD KG V KAP    V  
Sbjct: 238 SWADIASKPAKQQPKLKTKN--GIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALV-- 293

Query: 297 PQTIIQ----QPQPLIQP----PPLVQSQLPQQ-QPQPPQPQQQQGPQPQAQPHQVQPQQ 347
            Q I Q     PQP+ Q     PP+ Q+ + QQ QP PP P Q         P Q+  QQ
Sbjct: 294 -QNIGQPTQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQ---------PAQLSVQQ 343

Query: 348 QQLQ-NRWVAPRNRGAGFNQN----NGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAIN 402
           Q  Q  RWVAPRNRG+GF  N    NG G    G G  P        E HPVLEKL++IN
Sbjct: 344 QAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPS-------EPHPVLEKLRSIN 396

Query: 403 NYNPKDFDWNLKNGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLY 462
           NYNPKDFDWNLK+GRVFIIKSYSEDDIHRSIKY+IWCSTEHGNKRLDAAYRS+NGKGP+Y
Sbjct: 397 NYNPKDFDWNLKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVY 456

Query: 463 LLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLE 522
           LLFSVNGSGHFCGVAEMKS VDYN  AGVWSQDKWKG+F+V+WIFVKDVPN+QLRHIRLE
Sbjct: 457 LLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLE 516

Query: 523 NNDNKPVTNSRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRER 580
           NN+NKPVTNSRDTQEVPLEKAKQVLKIIA++KHTTSIFDDF+HYEKRQEEEE++++ER
Sbjct: 517 NNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKER 574


>gi|31377750 YTH domain family, member 1 [Homo sapiens]
          Length = 559

 Score =  790 bits (2039), Expect = 0.0
 Identities = 403/595 (67%), Positives = 459/595 (77%), Gaps = 46/595 (7%)

Query: 1   MSATSVD-QRPKGQGNKVSVQNGSIHQKDAVNDDDFEPYLSSQTNQSNSYPPMSDPYMPS 59
           MSATSVD QR KGQ NKV  QNGS+HQKD V+D+DFEPYL+ Q+NQSNSYP MSDPY+ S
Sbjct: 1   MSATSVDTQRTKGQDNKV--QNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSS 58

Query: 60  YYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFL 119
           YY PSIGFPYSL EA WSTAGD P+PYLTTYGQ+SNG+HH++ D VF QPG LGN    +
Sbjct: 59  YYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNN---I 115

Query: 120 GQHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLS 179
            QH FNFFP N  FS WGTSGSQGQ TQSSAY SSY YPPSSLG  + DGQ GF +DTLS
Sbjct: 116 YQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLS 175

Query: 180 KVPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIAT-NSVPPVSSAAPKPTSW 238
           K PG++S+EQGM GLKIG D++++  KTVG+ +SS  +T + + N    V+    KPTSW
Sbjct: 176 KAPGMNSLEQGMVGLKIG-DVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSW 234

Query: 239 AAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQ 298
           AAIA KPAKPQPK+K K    +GG  +PPPPIKHNM+IGTWD KG V KAP         
Sbjct: 235 AAIASKPAKPQPKMKTKSGPVMGGG-LPPPPIKHNMDIGTWDNKGPVPKAP--------- 284

Query: 299 TIIQQPQPLIQPPPLVQSQLPQQQPQP---PQPQQQQGPQPQAQPHQVQPQ----QQQLQ 351
                              +PQQ P P   PQPQQ   P P   P   QPQ    QQ  Q
Sbjct: 285 -------------------VPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQ 325

Query: 352 NRWVAPRNRGAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDW 411
            RWVAPRNR A F Q+ GAGS++   G V  +++PS VE HPVLEKLKA ++YNPK+F+W
Sbjct: 326 TRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPS-VESHPVLEKLKAAHSYNPKEFEW 384

Query: 412 NLKNGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSG 471
           NLK+GRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLD+A+R ++ KGP+YLLFSVNGSG
Sbjct: 385 NLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSG 444

Query: 472 HFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTN 531
           HFCGVAEMKS VDY   AGVWSQDKWKGKF+V+WIFVKDVPNNQLRHIRLENNDNKPVTN
Sbjct: 445 HFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTN 504

Query: 532 SRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRER-NRNKQ 585
           SRDTQEVPLEKAKQVLKII+++KHTTSIFDDFAHYEKRQEEEE +R+ER +RNKQ
Sbjct: 505 SRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNKQ 559


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 44/133 (33%), Positives = 68/133 (51%), Gaps = 4/133 (3%)

Query: 417  RVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGHFCGV 476
            R FI+KS +  ++  S +  IW +T    ++L+ A+        +YL+FSV GSGHF G 
Sbjct: 1289 RYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWE---SSIVYLVFSVQGSGHFQGF 1345

Query: 477  AEMKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQ 536
            + M S +        W      G F+V+WI  + +P     H+    NDNK V  SRD Q
Sbjct: 1346 SRMSSEIGREKSQD-WGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQ 1404

Query: 537  EVPLEKAKQVLKI 549
            E+     +Q+L++
Sbjct: 1405 ELEPLVGEQLLQL 1417


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 49/174 (28%), Positives = 80/174 (45%), Gaps = 13/174 (7%)

Query: 383 SASPSSVEVHPVLEKL----KAINNYNPKDFDWNLKNGRVFIIKSYSEDDIHRSIKYSIW 438
           SAS S        EKL    +A+         + L++ R F+IKS + +++  +    +W
Sbjct: 318 SASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVW 377

Query: 439 CSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVW------ 492
            +     K+L+ A+RS      + L+FSV  SG F G A + S   +      W      
Sbjct: 378 STLPVNEKKLNLAFRSARS---VILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGM 434

Query: 493 SQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQV 546
           S     G F++ WI  +++P  +  H+    N++KPV   RD QE+ LE   Q+
Sbjct: 435 SAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQL 488


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 45/130 (34%), Positives = 62/130 (47%), Gaps = 11/130 (8%)

Query: 224  SVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKG 283
            ++PP    A  P    A+ + P  PQP +     V +     P PP+  +M +  + ++ 
Sbjct: 879  ALPP--KPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLT-SMQMQLYLQQ- 934

Query: 284  SVVKAPPTQPVLPPQTIIQQPQPLIQPP--PLVQSQLPQQQPQPPQPQQQQGPQPQAQPH 341
             + K  P  P+LP   +  QP P + PP  P VQ QL QQ P PP PQ Q  PQ Q QP 
Sbjct: 935  -LQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPP 993

Query: 342  ----QVQPQQ 347
                 +QP Q
Sbjct: 994  PRPVHLQPMQ 1003



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/50 (48%), Positives = 27/50 (54%), Gaps = 5/50 (10%)

Query: 298 QTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQ 347
           Q + Q P P+ Q PP      PQQ P PP PQQQQ P P   P  + PQQ
Sbjct: 744 QQMQQAPAPVPQQPP----PPPQQPPPPPPPQQQQQPPPPPPPPSM-PQQ 788



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 22/51 (43%), Positives = 24/51 (47%), Gaps = 7/51 (13%)

Query: 290 PTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQP 340
           P QP  PPQ    QP P   PPP  Q Q P   P PP   QQ  P  ++ P
Sbjct: 754 PQQPPPPPQ----QPPP---PPPPQQQQQPPPPPPPPSMPQQAAPAMKSSP 797



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 23/63 (36%), Positives = 26/63 (41%), Gaps = 12/63 (19%)

Query: 289 PPTQ------PVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQ 342
           PP Q      P + P  I+Q P   + PP       P Q P P  PQ Q  P P  QP Q
Sbjct: 216 PPVQATPHPFPAVTPDLIVQTPVMTVVPPQ------PLQTPPPVPPQPQPPPAPAPQPVQ 269

Query: 343 VQP 345
             P
Sbjct: 270 SHP 272



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 7/60 (11%)

Query: 297 PQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVA 356
           P  + QQP P  Q PP       QQQP PP       P P + P Q  P  +     ++A
Sbjct: 750 PAPVPQQPPPPPQQPPPPPPPQQQQQPPPP-------PPPPSMPQQAAPAMKSSPPPFIA 802



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 37/144 (25%), Positives = 53/144 (36%), Gaps = 25/144 (17%)

Query: 226 PPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPP------PPIKHNMNIGTW 279
           PP     P P       + P  P P   P+       S+ PP      P ++  +    +
Sbjct: 758 PPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVF 817

Query: 280 DEKGS----VVKAPPTQPVLPPQTIIQQP----------QPLIQPPPLVQSQLPQQQPQP 325
           D  G     ++  P  QP LPP   + QP          Q  +  PP + + LPQQ  +P
Sbjct: 818 DPIGHFTQPILHLP--QPELPPH--LPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRP 873

Query: 326 PQPQQQQGPQPQAQPHQVQPQQQQ 349
                   P+P A+P  V P   Q
Sbjct: 874 SNRAAALPPKP-ARPPAVSPALTQ 896



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 16/32 (50%), Positives = 16/32 (50%)

Query: 320 QQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQ 351
           QQ  Q P P  QQ P P  QP    P QQQ Q
Sbjct: 744 QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQ 775



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 2/61 (3%)

Query: 292 QPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQ 351
           QP  PP      P P + P  +VQ+  P     PPQP Q   P P        P  Q +Q
Sbjct: 212 QPNPPPVQATPHPFPAVTPDLIVQT--PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQ 269

Query: 352 N 352
           +
Sbjct: 270 S 270



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 28/107 (26%), Positives = 40/107 (37%), Gaps = 11/107 (10%)

Query: 222 TNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDE 281
           T +  P  S  P  T  A+   +   PQP   P     +  +  P P +  ++ + T   
Sbjct: 186 TGTAKPGVSTVPNTTQ-ASTPPQTQTPQPNPPP-----VQATPHPFPAVTPDLIVQT--- 236

Query: 282 KGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQP 328
              V+   P QP+  P  +  QPQP   P P      P      PQP
Sbjct: 237 --PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQP 281


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 9/140 (6%)

Query: 413 LKNGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGH 472
           L++ R F+IKS + +++  +    +W +     K+L+ A+RS      + L+FSV  SG 
Sbjct: 334 LQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARS---VILIFSVRESGK 390

Query: 473 FCGVAEMKSVVDYNAYAGVW------SQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDN 526
           F G A + S   +      W      S     G F++ WI  +++P  +  H+    N++
Sbjct: 391 FQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEH 450

Query: 527 KPVTNSRDTQEVPLEKAKQV 546
           KPV   RD QE+ LE   Q+
Sbjct: 451 KPVKIGRDGQEIELECGTQL 470


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 62/218 (28%), Positives = 85/218 (38%), Gaps = 58/218 (26%)

Query: 140  GSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQGMTGLKIGGD 199
            GS   +T++    SSY    S++G +I    +   + +   +   SS+ Q          
Sbjct: 1554 GSIESTTENYENPSSYD---STMGGSICGNSSSQSSCSYGGLSSSSSLTQS--------- 1601

Query: 200  LTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVG 259
             +  VT+ + +  SS  M  +  +SV P ++ + K      + R P+  Q +        
Sbjct: 1602 -SCVVTQQMASMGSSCSM--MQQSSVQPAANCSIKSPQSCVVERPPSNQQQQ-------- 1650

Query: 260  IGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLP 319
                  PPPP                   PP QP  PP     QPQP  QPPP    Q P
Sbjct: 1651 ------PPPP-------------------PPQQPQPPPP----QPQPAPQPPP--PQQQP 1679

Query: 320  QQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAP 357
            QQQPQ PQPQQ   P P   P Q  P  Q   N    P
Sbjct: 1680 QQQPQ-PQPQQ---PPPPPPPQQQPPLSQCSMNNSFTP 1713


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 62/218 (28%), Positives = 85/218 (38%), Gaps = 58/218 (26%)

Query: 140  GSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQGMTGLKIGGD 199
            GS   +T++    SSY    S++G +I    +   + +   +   SS+ Q          
Sbjct: 1554 GSIESTTENYENPSSYD---STMGGSICGNSSSQSSCSYGGLSSSSSLTQS--------- 1601

Query: 200  LTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVG 259
             +  VT+ + +  SS  M  +  +SV P ++ + K      + R P+  Q +        
Sbjct: 1602 -SCVVTQQMASMGSSCSM--MQQSSVQPAANCSIKSPQSCVVERPPSNQQQQ-------- 1650

Query: 260  IGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLP 319
                  PPPP                   PP QP  PP     QPQP  QPPP    Q P
Sbjct: 1651 ------PPPP-------------------PPQQPQPPPP----QPQPAPQPPP--PQQQP 1679

Query: 320  QQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAP 357
            QQQPQ PQPQQ   P P   P Q  P  Q   N    P
Sbjct: 1680 QQQPQ-PQPQQ---PPPPPPPQQQPPLSQCSMNNSFTP 1713


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 62/218 (28%), Positives = 85/218 (38%), Gaps = 58/218 (26%)

Query: 140  GSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQGMTGLKIGGD 199
            GS   +T++    SSY    S++G +I    +   + +   +   SS+ Q          
Sbjct: 1554 GSIESTTENYENPSSYD---STMGGSICGNSSSQSSCSYGGLSSSSSLTQS--------- 1601

Query: 200  LTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVG 259
             +  VT+ + +  SS  M  +  +SV P ++ + K      + R P+  Q +        
Sbjct: 1602 -SCVVTQQMASMGSSCSM--MQQSSVQPAANCSIKSPQSCVVERPPSNQQQQ-------- 1650

Query: 260  IGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLP 319
                  PPPP                   PP QP  PP     QPQP  QPPP    Q P
Sbjct: 1651 ------PPPP-------------------PPQQPQPPPP----QPQPAPQPPP--PQQQP 1679

Query: 320  QQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAP 357
            QQQPQ PQPQQ   P P   P Q  P  Q   N    P
Sbjct: 1680 QQQPQ-PQPQQ---PPPPPPPQQQPPLSQCSMNNSFTP 1713


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 47/127 (37%), Positives = 58/127 (45%), Gaps = 22/127 (17%)

Query: 242  ARKPAKPQPKLKPKGN-----------VGIGGSAVPPPPIKHNMNIGTWDEK-GSVVKAP 289
            A KP K +P  K K +            G+  +  PP P +  +N+     K       P
Sbjct: 911  ANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRP 970

Query: 290  PTQPVLPPQT--IIQQPQPLIQ---PPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQ 344
            P  P  P +   + Q P  L+Q   PPP    Q PQQQPQP  PQQQQ P P +QP   Q
Sbjct: 971  PGYPSQPVEQRPLQQMPPQLMQHVAPPP----QPPQQQPQPQLPQQQQ-PPPPSQPQSQQ 1025

Query: 345  PQQQQLQ 351
             QQQQ Q
Sbjct: 1026 QQQQQQQ 1032



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 69/328 (21%), Positives = 117/328 (35%), Gaps = 34/328 (10%)

Query: 37  PYLSSQTNQSNSYPPMSDPYMPSYYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNG 96
           P ++    Q    PP ++P +P  +   +  P   G       G+ P  ++    Q  N 
Sbjct: 444 PTVNQTQQQMGPRPPQNNP-LPQGFQQPVSSP---GRNPMVQQGNVPPNFMVMQQQPPNQ 499

Query: 97  EHHYIPDGVFSQPGALGNTPPFL--GQHGFNFFPGNADFSTWGTSGSQG----QSTQSSA 150
               +  G+   P  L   PP    GQ   NF  G    +T  T G+ G    Q+ Q+  
Sbjct: 500 GPQSLHPGLGGMPKRL---PPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQ 556

Query: 151 YSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQ-GMTGLKIGGDLTAAVTKTVG 209
           ++   G  P      ++ G       +L  + G  + +Q G +G+              G
Sbjct: 557 HAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQG 616

Query: 210 TALSSSGMTS--IATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLK---PKGNVGIGGSA 264
                 GM    + +            P +   ++R    PQ ++    P  N+G     
Sbjct: 617 PPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQR 676

Query: 265 VPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQ-- 322
           + PP  K  ++     ++G  + AP  Q + P   ++ Q  P+I+     Q Q  +QQ  
Sbjct: 677 MTPP--KQMLS-----QQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFN 729

Query: 323 ------PQPPQPQQQQGPQPQAQPHQVQ 344
                   P   Q  +GP P  Q + VQ
Sbjct: 730 TQNQSNVMPGPAQIMRGPTPNMQGNMVQ 757



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 43/136 (31%), Positives = 55/136 (40%), Gaps = 17/136 (12%)

Query: 217 MTSIATNSVPP---VSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHN 273
           M + AT  +PP   VSS+   P            P P+L+P+       S    P +   
Sbjct: 176 MNNPATVMIPPGGNVSSSMMAPG-----------PNPELQPRTPRPASQSDAMDPLLSGL 224

Query: 274 MNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQG 333
                    GS+  APP  P + P ++ +Q  P   P    Q Q  QQQ Q  Q QQQQ 
Sbjct: 225 HIQQQSHPSGSL--APPHHP-MQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQ 281

Query: 334 PQPQAQPHQVQPQQQQ 349
            Q Q Q    Q  QQQ
Sbjct: 282 QQQQLQARPPQQHQQQ 297



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 39/146 (26%), Positives = 47/146 (32%), Gaps = 25/146 (17%)

Query: 266 PPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQ-----PQPLIQP---------- 310
           PPPP        +         + P Q   P    +Q      P PL QP          
Sbjct: 372 PPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASS 431

Query: 311 PPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQL----QNRWVAPRNRGAGF-- 364
           P   Q   P   P   Q QQQ GP+P       Q  QQ +    +N  V   N    F  
Sbjct: 432 PSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMV 491

Query: 365 ----NQNNGAGSENFGLGVVPVSASP 386
                 N G  S + GLG +P    P
Sbjct: 492 MQQQPPNQGPQSLHPGLGGMPKRLPP 517


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
           [Homo sapiens]
          Length = 1125

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 55/175 (31%), Positives = 68/175 (38%), Gaps = 19/175 (10%)

Query: 208 VGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPK-LKPKGNV-GIGGSAV 265
           +G    S+G+       +P        P         P +P P  +  +G   G GG A+
Sbjct: 818 IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAM 877

Query: 266 PPPPIKHNMNIGTWDEKGSVVKAPPTQPVL----PPQTIIQQPQPLIQPPPLVQSQLPQQ 321
           PPP   H M  G +   G  V+ P   P L    P     +      QPP   Q Q   Q
Sbjct: 878 PPP---HGMK-GPFPPHGPFVR-PGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQ 932

Query: 322 QPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNNGAGSENFG 376
            PQ PQ QQQQ P P  QP   Q Q QQ +N      NR      N+G   E FG
Sbjct: 933 APQQPQQQQQQQPPPSQQPPPTQQQPQQFRN-----DNRQ---QFNSGRDQERFG 979



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 3/133 (2%)

Query: 221 ATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWD 280
           A  +  P ++  P PT+    A  PA   P   P+   G  G  +  P    + N+  + 
Sbjct: 284 AVTTTAPAAAVPPAPTATVPAAAAPAAASPP-PPQAPFGFPGDGMQQPAYTQHQNMDQFQ 342

Query: 281 EKGSVVKAPPTQPVLPPQTIIQQPQ-PLIQPPPLVQSQLPQQQPQPPQPQQQQGP-QPQA 338
            +   ++  P    +P     Q P   L+  PP      P   P PP  Q  Q   Q Q 
Sbjct: 343 PRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402

Query: 339 QPHQVQPQQQQLQ 351
           +P   +P QQ+++
Sbjct: 403 EPLTQKPHQQEME 415



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 37/126 (29%), Positives = 49/126 (38%), Gaps = 13/126 (10%)

Query: 250  PKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTII-QQPQPLI 308
            P ++P G  G+GG    P         G  D  G   + PP QP   PQ    QQPQ   
Sbjct: 892  PFVRPGGMPGLGGPGPGPG--------GPEDRDGR--QQPPQQPQQQPQPQAPQQPQQQQ 941

Query: 309  QPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNN 368
            Q  P    Q P  Q QP Q +     Q  +   Q +  ++   NR    R R    N+N+
Sbjct: 942  QQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYG--NRND 999

Query: 369  GAGSEN 374
               + N
Sbjct: 1000 DRDNSN 1005



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 4/47 (8%)

Query: 288 APPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGP 334
           +P  +P+  P   I  P P+  PPP    Q+P  QP PP     Q P
Sbjct: 656 SPIPKPLPVPVPPIPVPAPITVPPP----QVPPHQPGPPVVGALQPP 698


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 55/175 (31%), Positives = 68/175 (38%), Gaps = 19/175 (10%)

Query: 208 VGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPK-LKPKGNV-GIGGSAV 265
           +G    S+G+       +P        P         P +P P  +  +G   G GG A+
Sbjct: 825 IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAM 884

Query: 266 PPPPIKHNMNIGTWDEKGSVVKAPPTQPVL----PPQTIIQQPQPLIQPPPLVQSQLPQQ 321
           PPP   H M  G +   G  V+ P   P L    P     +      QPP   Q Q   Q
Sbjct: 885 PPP---HGMK-GPFPPHGPFVR-PGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQ 939

Query: 322 QPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNNGAGSENFG 376
            PQ PQ QQQQ P P  QP   Q Q QQ +N      NR      N+G   E FG
Sbjct: 940 APQQPQQQQQQQPPPSQQPPPTQQQPQQFRN-----DNRQ---QFNSGRDQERFG 986



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 3/133 (2%)

Query: 221 ATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWD 280
           A  +  P ++  P PT+    A  PA   P   P+   G  G  +  P    + N+  + 
Sbjct: 269 AVTTTAPAAAVPPAPTATVPAAAAPAAASPP-PPQAPFGFPGDGMQQPAYTQHQNMDQFQ 327

Query: 281 EKGSVVKAPPTQPVLPPQTIIQQPQ-PLIQPPPLVQSQLPQQQPQPPQPQQQQGP-QPQA 338
            +   ++  P    +P     Q P   L+  PP      P   P PP  Q  Q   Q Q 
Sbjct: 328 PRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 387

Query: 339 QPHQVQPQQQQLQ 351
           +P   +P QQ+++
Sbjct: 388 EPLTQKPHQQEME 400



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 37/126 (29%), Positives = 49/126 (38%), Gaps = 13/126 (10%)

Query: 250  PKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTII-QQPQPLI 308
            P ++P G  G+GG    P         G  D  G   + PP QP   PQ    QQPQ   
Sbjct: 899  PFVRPGGMPGLGGPGPGPG--------GPEDRDGR--QQPPQQPQQQPQPQAPQQPQQQQ 948

Query: 309  QPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNN 368
            Q  P    Q P  Q QP Q +     Q  +   Q +  ++   NR    R R    N+N+
Sbjct: 949  QQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYG--NRND 1006

Query: 369  GAGSEN 374
               + N
Sbjct: 1007 DRDNSN 1012



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 4/47 (8%)

Query: 288 APPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGP 334
           +P  +P+  P   I  P P+  PPP    Q+P  QP PP     Q P
Sbjct: 641 SPIPKPLPVPVPPIPVPAPITVPPP----QVPPHQPGPPVVGALQPP 683


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo
            sapiens]
          Length = 1147

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 55/175 (31%), Positives = 68/175 (38%), Gaps = 19/175 (10%)

Query: 208  VGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPK-LKPKGNV-GIGGSAV 265
            +G    S+G+       +P        P         P +P P  +  +G   G GG A+
Sbjct: 840  IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAM 899

Query: 266  PPPPIKHNMNIGTWDEKGSVVKAPPTQPVL----PPQTIIQQPQPLIQPPPLVQSQLPQQ 321
            PPP   H M  G +   G  V+ P   P L    P     +      QPP   Q Q   Q
Sbjct: 900  PPP---HGMK-GPFPPHGPFVR-PGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQ 954

Query: 322  QPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNNGAGSENFG 376
             PQ PQ QQQQ P P  QP   Q Q QQ +N      NR      N+G   E FG
Sbjct: 955  APQQPQQQQQQQPPPSQQPPPTQQQPQQFRN-----DNRQ---QFNSGRDQERFG 1001



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 3/133 (2%)

Query: 221 ATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWD 280
           A  +  P ++  P PT+    A  PA   P   P+   G  G  +  P    + N+  + 
Sbjct: 284 AVTTTAPAAAVPPAPTATVPAAAAPAAASPP-PPQAPFGFPGDGMQQPAYTQHQNMDQFQ 342

Query: 281 EKGSVVKAPPTQPVLPPQTIIQQPQ-PLIQPPPLVQSQLPQQQPQPPQPQQQQGP-QPQA 338
            +   ++  P    +P     Q P   L+  PP      P   P PP  Q  Q   Q Q 
Sbjct: 343 PRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402

Query: 339 QPHQVQPQQQQLQ 351
           +P   +P QQ+++
Sbjct: 403 EPLTQKPHQQEME 415



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 37/126 (29%), Positives = 49/126 (38%), Gaps = 13/126 (10%)

Query: 250  PKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTII-QQPQPLI 308
            P ++P G  G+GG    P         G  D  G   + PP QP   PQ    QQPQ   
Sbjct: 914  PFVRPGGMPGLGGPGPGPG--------GPEDRDGR--QQPPQQPQQQPQPQAPQQPQQQQ 963

Query: 309  QPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNN 368
            Q  P    Q P  Q QP Q +     Q  +   Q +  ++   NR    R R    N+N+
Sbjct: 964  QQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYG--NRND 1021

Query: 369  GAGSEN 374
               + N
Sbjct: 1022 DRDNSN 1027



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 4/47 (8%)

Query: 288 APPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGP 334
           +P  +P+  P   I  P P+  PPP    Q+P  QP PP     Q P
Sbjct: 656 SPIPKPLPVPVPPIPVPAPITVPPP----QVPPHQPGPPVVGALQPP 698


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 40/128 (31%), Positives = 53/128 (41%), Gaps = 14/128 (10%)

Query: 216 GMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMN 275
           G  + A  + PP + A P P +  A A     P+             +A   PP      
Sbjct: 117 GAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRA----------AAAAATAPPSPGPAQ 166

Query: 276 IGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLP--QQQPQPP-QPQQQQ 332
            G   ++ + + APP  P  PP  +     P   PPP V ++ P     PQPP  PQQQQ
Sbjct: 167 PGPRAQRAAPLAAPPPAPAAPP-AVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQ 225

Query: 333 GPQPQAQP 340
            P PQ QP
Sbjct: 226 PPPPQPQP 233



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 37/112 (33%), Positives = 46/112 (41%), Gaps = 17/112 (15%)

Query: 227 PVSSAAPK--PTSWAAIARKPAKPQPKLK-PKGNVGIGGSAVPPPPIKHNMNIGTWDEKG 283
           PV++AAP   P + AA A  P  P P    P+       +A PP P              
Sbjct: 139 PVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPA------------A 186

Query: 284 SVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQ 335
               APP  P   P   +   +P + PPP  Q   P QQ QPP PQ Q  P+
Sbjct: 187 PPAVAPPAGPRRAPPPAVAAREPPLPPPP--QPPAPPQQQQPPPPQPQPPPE 236


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 55/194 (28%), Positives = 78/194 (40%), Gaps = 32/194 (16%)

Query: 177 TLSKVPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPK-- 234
           +L  +P   S   G+ G       +A + +    +  +S   S A +    + SA P   
Sbjct: 282 SLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGT 341

Query: 235 -PTSWAAIAR---KPAKPQPKLKPKGNVGIGGSAVPPPPIK--HNMNIGTWDEKGSVVKA 288
            P SW  ++R    P+ PQP+  P+           P P+     +    W+   S    
Sbjct: 342 LPRSWQPVSRIPMPPSSPQPRGAPRQR---------PIPLSMIFKLQNAFWEHGAS---- 388

Query: 289 PPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPP-QPQQQQGPQPQAQPHQVQPQQ 347
              + +LP   +  +      PPP +Q Q PQ QPQP  QPQ Q  PQPQ QP    P  
Sbjct: 389 ---RAMLPGSPLFTRA-----PPPKLQPQ-PQPQPQPQSQPQPQLPPQPQTQPQTPTPAP 439

Query: 348 QQLQNRWVAPRNRG 361
           Q  Q  W  P N G
Sbjct: 440 QHPQQTW-PPVNEG 452


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 55/194 (28%), Positives = 78/194 (40%), Gaps = 32/194 (16%)

Query: 177 TLSKVPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPK-- 234
           +L  +P   S   G+ G       +A + +    +  +S   S A +    + SA P   
Sbjct: 282 SLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGT 341

Query: 235 -PTSWAAIAR---KPAKPQPKLKPKGNVGIGGSAVPPPPIK--HNMNIGTWDEKGSVVKA 288
            P SW  ++R    P+ PQP+  P+           P P+     +    W+   S    
Sbjct: 342 LPRSWQPVSRIPMPPSSPQPRGAPRQR---------PIPLSMIFKLQNAFWEHGAS---- 388

Query: 289 PPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPP-QPQQQQGPQPQAQPHQVQPQQ 347
              + +LP   +  +      PPP +Q Q PQ QPQP  QPQ Q  PQPQ QP    P  
Sbjct: 389 ---RAMLPGSPLFTRA-----PPPKLQPQ-PQPQPQPQSQPQPQLPPQPQTQPQTPTPAP 439

Query: 348 QQLQNRWVAPRNRG 361
           Q  Q  W  P N G
Sbjct: 440 QHPQQTW-PPVNEG 452


>gi|190343021 Sec24-related protein D [Homo sapiens]
          Length = 1032

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 69/284 (24%), Positives = 98/284 (34%), Gaps = 69/284 (24%)

Query: 90  YGQMSNGEHHYIPDGVFSQPGALGNT---------PPFLGQHGFNFFPGNADFSTWGTSG 140
           YG   +  H   P G+    G LG T         PP  G H F                
Sbjct: 26  YGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFG--------------- 70

Query: 141 SQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQGMTGLKIGGDL 200
                 Q+ A+++  G+PP         G     N   S  P   S +    G      +
Sbjct: 71  ------QNGAHAT--GHPPQRF-----PGPPPVNNVASSHAPYQPSAQSSYPG-----PI 112

Query: 201 TAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGI 260
           + +    +G+ LS+  + S  +   PP S   P P S  ++   P  PQP +   G+   
Sbjct: 113 STSSVTQLGSQLSAMQINSYGSGMAPP-SQGPPGPLSATSLQTPPRPPQPSILQPGS--- 168

Query: 261 GGSAVPPPPIKHN------MNIGTWDEKGSVVKAPPTQ----PVLPPQTIIQ--QPQPLI 308
               +PPPP   N      + +  +   G     PP      P LP QT+     PQ   
Sbjct: 169 --QVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQAN 226

Query: 309 QPPPLVQSQL---------PQQQPQPPQPQQQQGPQPQAQPHQV 343
             P +  +QL         P Q   PPQPQ++  P     P QV
Sbjct: 227 SGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQV 270



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 37/154 (24%), Positives = 53/154 (34%), Gaps = 21/154 (13%)

Query: 226 PPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSV 285
           PP     P P +  A +  P +P  +    G +    S      +   ++    +  GS 
Sbjct: 80  PPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPI----STSSVTQLGSQLSAMQINSYGSG 135

Query: 286 VKAPPTQ-------------PVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQP---PQPQ 329
           + APP+Q             P  PPQ  I QP   + PPP      P   P P    +P 
Sbjct: 136 M-APPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPD 194

Query: 330 QQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAG 363
              GP P    +Q  P   Q       P+   +G
Sbjct: 195 GLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSG 228


>gi|38261971 cyclic AMP-regulated phosphoprotein, 21 kD isoform 1
           [Homo sapiens]
          Length = 812

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 68/236 (28%), Positives = 95/236 (40%), Gaps = 19/236 (8%)

Query: 127 FPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISS 186
           F GN D S   TSGS+  S+++    S +        RA +   +   N  L      ++
Sbjct: 331 FRGNRDGSG-RTSGSRQSSSENELKWSDHQ-------RAWSSTDSDSSNRNLKPAMTKTA 382

Query: 187 IEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPA 246
              G+T L   GD T++ T++ G    +   +S +  S   +S   P P     +    A
Sbjct: 383 SFGGITVLT-RGDSTSS-TRSTGKLSKAGSESSSSAGSSGSLSRTHP-PLQSTPLVSGVA 439

Query: 247 KPQPKLKPKGNVGIGGSAVPPPP--IKHNMNIGTWDEKGSVVKAPPT-QPVLPPQTIIQQ 303
              P   P    GIGG   P     I   +   T    GS++  P T QP + P      
Sbjct: 440 AGSPGCVPYPENGIGGQVAPSSTSYILLPLEAATGIPPGSILLNPHTGQPFVNPDGTPAI 499

Query: 304 PQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRN 359
             P     PL  + + Q Q QP  PQQQ  PQPQ    QVQP Q Q+    V  R+
Sbjct: 500 YNPPTSQQPLRSAMVGQSQQQP--PQQQPSPQPQ---QQVQPPQPQMAGPLVTQRD 550



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 32/120 (26%), Positives = 42/120 (35%), Gaps = 14/120 (11%)

Query: 229 SSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKA 288
           S   P+P S   +      PQP  +P   +   G  +P          G +   G  +  
Sbjct: 566 SGETPEPPS-GPVYPSSLMPQPAQQPSYVIASTGQQLPT---------GGFSGSGPPISQ 615

Query: 289 PPTQPVLPPQTIIQQPQPLIQPPPLVQS-QLP---QQQPQPPQPQQQQGPQPQAQPHQVQ 344
              QP   PQ  +QQP P   P     S Q P    QQ +P  P Q    + Q  P   Q
Sbjct: 616 QVLQPPPSPQGFVQQPPPAQMPVYYYPSGQYPTSTTQQYRPMAPVQYNAQRSQQMPQAAQ 675


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 40/117 (34%), Positives = 54/117 (46%), Gaps = 18/117 (15%)

Query: 239  AAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQ 298
            +A+A+ P +P   + P     +  + VPP P     N+          +A P QP LPPQ
Sbjct: 901  SAVAQLPGQP---VYPAAFPQMAPTDVPPSPHHTVQNM----------RATPPQPALPPQ 947

Query: 299  TIIQQPQPLIQPPPLVQSQ--LPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNR 353
              +  PQP++ P P +  Q  LP Q  +PPQP     PQP   P  V P Q  L  R
Sbjct: 948  PTLP-PQPVLPPQPTLPPQPVLPPQPTRPPQPVLP--PQPMLPPQPVLPPQPALPVR 1001



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 48/175 (27%), Positives = 70/175 (40%), Gaps = 39/175 (22%)

Query: 181  VPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPT--SW 238
            +P ++    G+  L I     +AV +  G  +  +    +A   VPP    +P  T  + 
Sbjct: 884  IPLLAVAPPGVAALSIH----SAVAQLPGQPVYPAAFPQMAPTDVPP----SPHHTVQNM 935

Query: 239  AAIARKPA-KPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPP 297
             A   +PA  PQP L P+         +PP P                    P QPVLPP
Sbjct: 936  RATPPQPALPPQPTLPPQ-------PVLPPQPTL------------------PPQPVLPP 970

Query: 298  QTIIQQPQPLIQPPPLVQSQ--LPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQL 350
            Q   + PQP++ P P++  Q  LP Q   P +P+  Q   P+       P  Q L
Sbjct: 971  QPT-RPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQIL 1024



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 39/149 (26%), Positives = 55/149 (36%), Gaps = 10/149 (6%)

Query: 209 GTALSSSGMTSIATNSVPPVSSAAPKPTSWAA---IARKPAKPQ--PKL----KPKGNVG 259
           G+ + S   +S  +  +  ++ AAP P        ++  P  PQ  P L    +P    G
Sbjct: 621 GSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPG 680

Query: 260 IGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLP 319
           +   +VP P    ++     D   S     P  P  P  T   QP P  Q PP +    P
Sbjct: 681 LPVGSVPAPACPPSLQQHFPDPAMSFAPVLPP-PSTPMPTGPGQPAPPGQQPPPLAQPTP 739

Query: 320 QQQPQPPQPQQQQGPQPQAQPHQVQPQQQ 348
             Q   PQP     P P   P  + P  Q
Sbjct: 740 LPQVLAPQPVVPLQPVPPHLPPYLAPASQ 768



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 49/211 (23%), Positives = 68/211 (32%), Gaps = 40/211 (18%)

Query: 132 DFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQGM 191
           D     T  S  QS+Q S    S      S  + +       G      +P + + +Q  
Sbjct: 617 DSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQP- 675

Query: 192 TGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPK 251
                    TAA    VG+  + +   S+  +   P  S AP       +   P+ P P 
Sbjct: 676 ---------TAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAP-------VLPPPSTPMP- 718

Query: 252 LKPKGNVGIGGSAVP---PPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTI-------- 300
                  G G  A P   PPP+     +        VV   P  P LPP           
Sbjct: 719 ------TGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAP 772

Query: 301 -----IQQPQPLIQPPPLVQSQLPQQQPQPP 326
                +Q PQ  +QP   V  Q+P     PP
Sbjct: 773 AQLKPLQMPQAPLQPLAQVPPQMPPIPVVPP 803



 Score = 32.7 bits (73), Expect = 0.95
 Identities = 47/178 (26%), Positives = 62/178 (34%), Gaps = 36/178 (20%)

Query: 204 VTKTVGTALSSSGMTSIATNSVPPV-------------SSAAPKPTSWAAIARKPAK-PQ 249
           +T   G       +  + T +VPPV             S AAP P +  A+  +  K P 
Sbjct: 804 ITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPH 863

Query: 250 PK----------LKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQT 299
           P           + P     I   AV PP +   ++I       S V   P QPV P   
Sbjct: 864 PPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAA-LSIH------SAVAQLPGQPVYPAAF 916

Query: 300 IIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAP 357
               P  +   PP     +   +  PPQP     PQP   P  V P Q  L  + V P
Sbjct: 917 PQMAPTDV---PPSPHHTVQNMRATPPQPALP--PQPTLPPQPVLPPQPTLPPQPVLP 969



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 32/132 (24%), Positives = 44/132 (33%), Gaps = 29/132 (21%)

Query: 216  GMTSIATNSVPPVSS-AAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNM 274
            G+TS    S P   +  AP       +   P  P P+     +       +PPP  + + 
Sbjct: 1425 GLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSP 1484

Query: 275  NIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPP----PLVQSQLPQQ------QPQ 324
            + GT                  PQ  + QP PL+        L  SQLP         PQ
Sbjct: 1485 HSGT------------------PQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQ 1526

Query: 325  PPQPQQQQGPQP 336
            PP   +  G  P
Sbjct: 1527 PPSALESDGEGP 1538


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 94/374 (25%), Positives = 131/374 (35%), Gaps = 70/374 (18%)

Query: 36  EPYLSSQTN---------QSNSYPPMSDPYMPSYYAPSIGFPY--SLGEAAWSTAGDQPM 84
           EPY   Q N         Q NSY P    Y P   A ++  P   + G  A + AG +P 
Sbjct: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP 252

Query: 85  PYLTTYGQMSNGEHHYIPDGVFSQPG---ALGNTP-----PFLGQ--------HGFNFFP 128
           P  +     S+        G     G   A G TP     P L Q         G+  +P
Sbjct: 253 PSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYP 312

Query: 129 GNADFSTWGTSGSQGQ-------------STQSSAYSSSYGYPPSSLGRAITDGQAGFGN 175
           G  D+S     G  G+             +  ++A ++S G    S    ++ G +G G 
Sbjct: 313 GG-DYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGG 371

Query: 176 DTLSKVPGISSIEQGMTGLK---IGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAA 232
             L++ P  SS    M  ++    GG  T   ++  G     SG          P  S  
Sbjct: 372 QPLARTPQPSSPMDQMGKMRPQPYGG--TNPYSQQQGPP---SGPQQGHGYPGQPYGSQT 426

Query: 233 PKPTSWAAIARKPAKP-----QPKLKPKGNVGIGGSAVP-PPPIKHNMNIGTWDEKGSVV 286
           P+        R  +         ++ P G  G  G       P  +  +     ++    
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486

Query: 287 KAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGP------------ 334
           + PP+Q      +  QQPQ   QPP L  SQ P  Q QP QP  QQ P            
Sbjct: 487 QQPPSQTPHAQPSYQQQPQS--QPPQLQSSQPPYSQ-QPSQPPHQQSPAPYPSQQSTTQQ 543

Query: 335 QPQAQPHQVQPQQQ 348
            PQ+QP   QPQ Q
Sbjct: 544 HPQSQPPYSQPQAQ 557



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 79/363 (21%), Positives = 114/363 (31%), Gaps = 70/363 (19%)

Query: 37  PYLSSQTNQSNSYPPMSDPY-MPSYYAPSIGFPYSL--GEAAWSTAGDQP------MPYL 87
           P+   Q    +  PP   P+  PSY       P  L   +  +S    QP       PY 
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP 535

Query: 88  TTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLGQHGFNFFPGNADFSTWGTSGSQGQSTQ 147
           +   Q S  + H      +SQP A     P+  Q      P             Q Q +Q
Sbjct: 536 S---QQSTTQQHPQSQPPYSQPQAQS---PYQQQQPQQPAPSTLSQQA-AYPQPQSQQSQ 588

Query: 148 SSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQGMTGLKIG---------- 197
            +AYS     PP  L       Q  FG+   S  P ++S + G   + +           
Sbjct: 589 QTAYSQQRFPPPQEL------SQDSFGSQA-SSAPSMTSSKGGQEDMNLSLQSRPSSLPD 641

Query: 198 -----GDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPKL 252
                 DL       +   +S+SG++S       P  S     TS      +   P P  
Sbjct: 642 LSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVG 701

Query: 253 KPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPP 312
            P          + P  +  N             + PP  P     +I+         P 
Sbjct: 702 SPASVAQSRSGPLSPAAVPGN-------------QMPPRPPSGQSDSIMH--------PS 740

Query: 313 LVQSQLPQQQ---PQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNNG 369
           + QS + Q +    + PQ  Q   PQP +     QP   Q+        + G G  Q N 
Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQI--------HTGMGSYQQNS 792

Query: 370 AGS 372
            GS
Sbjct: 793 MGS 795



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 72/340 (21%), Positives = 110/340 (32%), Gaps = 77/340 (22%)

Query: 36   EPYLSSQTNQSNSYP--------PMSDPYMPSYYAP-----------SIGFPYSLGEAAW 76
            EP +  + N S   P        P S  Y PS Y P           S G  +S      
Sbjct: 1291 EPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFS----TQ 1346

Query: 77   STAGDQPMP-YLTTYGQMSNGEHHYIPDGVFSQP-----GALGNTPPFLGQHGFNFFPGN 130
             T    P P   TT  Q     +    DG +  P     G + + P   GQ       G 
Sbjct: 1347 GTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQ-------GQ 1399

Query: 131  ADFSTWGTSGSQGQSTQSSAYSS-------SYGYPPSSLGRAITDGQAG----------F 173
                    +  Q  S Q +A  S        YG    +   A T+ +            F
Sbjct: 1400 PQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQF 1459

Query: 174  GNDTLSKVPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSS-AA 232
            G D +S  PG ++ +Q M    +GG + A+  +         G   +  N     S+ +A
Sbjct: 1460 GRDRVSAPPGTNA-QQNMPPQMMGGPIQASA-EVAQQGTMWQGRNDMTYNYANRQSTGSA 1517

Query: 233  PKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQ 292
            P+  ++  + R         +                       G+W   G+  + PP  
Sbjct: 1518 PQGPAYHGVNRTDEMLHTDQRANHE-------------------GSWPSHGT--RQPPYG 1556

Query: 293  PVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQ 332
            P  P   + + P    QPPP +Q+ +PQ     P P+  +
Sbjct: 1557 PSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPME 1596



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 50/188 (26%), Positives = 68/188 (36%), Gaps = 52/188 (27%)

Query: 247  KPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQT------- 299
            + +P + P+GN+  G  A  P  +  N + G +    S  + PP Q     Q        
Sbjct: 1289 RTEPGIGPEGNMSTG--APQPNLMPSNPDSGMY----SPSRYPPQQQQQQQQRHDSYGNQ 1342

Query: 300  IIQQPQPLIQPPPLVQSQLPQQQPQ-----------PP------------------QPQQ 330
               Q  P   P P  Q+ + QQQ Q           PP                  QPQQ
Sbjct: 1343 FSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQ 1402

Query: 331  QQ----GPQPQAQPHQVQPQ-QQQLQNRW--VAPRNRGAGFNQNNGAGSEN---FGLGVV 380
            QQ     PQP +Q    QP  QQ + N++    P    A   +    G +N   F  G  
Sbjct: 1403 QQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRD 1462

Query: 381  PVSASPSS 388
             VSA P +
Sbjct: 1463 RVSAPPGT 1470


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 94/374 (25%), Positives = 131/374 (35%), Gaps = 70/374 (18%)

Query: 36  EPYLSSQTN---------QSNSYPPMSDPYMPSYYAPSIGFPY--SLGEAAWSTAGDQPM 84
           EPY   Q N         Q NSY P    Y P   A ++  P   + G  A + AG +P 
Sbjct: 193 EPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP 252

Query: 85  PYLTTYGQMSNGEHHYIPDGVFSQPG---ALGNTP-----PFLGQ--------HGFNFFP 128
           P  +     S+        G     G   A G TP     P L Q         G+  +P
Sbjct: 253 PSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYP 312

Query: 129 GNADFSTWGTSGSQGQ-------------STQSSAYSSSYGYPPSSLGRAITDGQAGFGN 175
           G  D+S     G  G+             +  ++A ++S G    S    ++ G +G G 
Sbjct: 313 GG-DYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGG 371

Query: 176 DTLSKVPGISSIEQGMTGLK---IGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAA 232
             L++ P  SS    M  ++    GG  T   ++  G     SG          P  S  
Sbjct: 372 QPLARTPQPSSPMDQMGKMRPQPYGG--TNPYSQQQGPP---SGPQQGHGYPGQPYGSQT 426

Query: 233 PKPTSWAAIARKPAKP-----QPKLKPKGNVGIGGSAVP-PPPIKHNMNIGTWDEKGSVV 286
           P+        R  +         ++ P G  G  G       P  +  +     ++    
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYS 486

Query: 287 KAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGP------------ 334
           + PP+Q      +  QQPQ   QPP L  SQ P  Q QP QP  QQ P            
Sbjct: 487 QQPPSQTPHAQPSYQQQPQS--QPPQLQSSQPPYSQ-QPSQPPHQQSPAPYPSQQSTTQQ 543

Query: 335 QPQAQPHQVQPQQQ 348
            PQ+QP   QPQ Q
Sbjct: 544 HPQSQPPYSQPQAQ 557



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 79/363 (21%), Positives = 114/363 (31%), Gaps = 70/363 (19%)

Query: 37  PYLSSQTNQSNSYPPMSDPY-MPSYYAPSIGFPYSL--GEAAWSTAGDQP------MPYL 87
           P+   Q    +  PP   P+  PSY       P  L   +  +S    QP       PY 
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP 535

Query: 88  TTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLGQHGFNFFPGNADFSTWGTSGSQGQSTQ 147
           +   Q S  + H      +SQP A     P+  Q      P             Q Q +Q
Sbjct: 536 S---QQSTTQQHPQSQPPYSQPQAQS---PYQQQQPQQPAPSTLSQQA-AYPQPQSQQSQ 588

Query: 148 SSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQGMTGLKIG---------- 197
            +AYS     PP  L       Q  FG+   S  P ++S + G   + +           
Sbjct: 589 QTAYSQQRFPPPQEL------SQDSFGSQA-SSAPSMTSSKGGQEDMNLSLQSRPSSLPD 641

Query: 198 -----GDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPKL 252
                 DL       +   +S+SG++S       P  S     TS      +   P P  
Sbjct: 642 LSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVG 701

Query: 253 KPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPP 312
            P          + P  +  N             + PP  P     +I+         P 
Sbjct: 702 SPASVAQSRSGPLSPAAVPGN-------------QMPPRPPSGQSDSIMH--------PS 740

Query: 313 LVQSQLPQQQ---PQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNNG 369
           + QS + Q +    + PQ  Q   PQP +     QP   Q+        + G G  Q N 
Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQI--------HTGMGSYQQNS 792

Query: 370 AGS 372
            GS
Sbjct: 793 MGS 795


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 41/117 (35%), Positives = 49/117 (41%), Gaps = 8/117 (6%)

Query: 226 PPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAV--PPPPIKHNMNIGTWDEKG 283
           PP     P P       +    P P  KP+G    GG+    PPPP K        D K 
Sbjct: 176 PPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS 232

Query: 284 SVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQ--QQPQ-PPQPQQQQGPQPQ 337
              ++PP +P  PP     QPQ    PP   Q   PQ   +PQ PP P + QGP PQ
Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 289



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 41/117 (35%), Positives = 49/117 (41%), Gaps = 8/117 (6%)

Query: 226 PPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAV--PPPPIKHNMNIGTWDEKG 283
           PP     P P       +    P P  KP+G    GG+    PPPP K        D K 
Sbjct: 114 PPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS 170

Query: 284 SVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQ--QQPQ-PPQPQQQQGPQPQ 337
              ++PP +P  PP     QPQ    PP   Q   PQ   +PQ PP P + QGP PQ
Sbjct: 171 RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 227



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 45/149 (30%), Positives = 56/149 (37%), Gaps = 17/149 (11%)

Query: 226 PPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAV--PPPPIKHNMNIGTWDEKG 283
           PP     P P       +    P P  KP+G    GG+    PPPP K          K 
Sbjct: 238 PPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 294

Query: 284 SVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQ---QQQGPQPQAQP 340
              ++PP +P  PP     QPQ    PPP      P  +PQ P PQ   + QGP P  +P
Sbjct: 295 RSSRSPPGKPQGPPPQGGNQPQ---GPPP------PPGKPQGPPPQGGNKPQGPPPPGKP 345

Query: 341 HQVQPQQQQLQNRWVAPRNRGAGFNQNNG 369
               PQ         +P  +  G  Q  G
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEG 374



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 41/117 (35%), Positives = 50/117 (42%), Gaps = 9/117 (7%)

Query: 226 PPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAV--PPPPIKHNMNIGTWDEKG 283
           PP     P P       +    P P  KP+G    GG+    PPPP K        D+  
Sbjct: 53  PPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 109

Query: 284 SVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQ--QQPQ-PPQPQQQQGPQPQ 337
           S  ++PP +P  PP     QPQ    PP   Q   PQ   +PQ PP P + QGP PQ
Sbjct: 110 SP-RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 165



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 39/124 (31%), Positives = 47/124 (37%), Gaps = 9/124 (7%)

Query: 226 PPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAV--PPPPIKHNMNIGTWDEKG 283
           PP     P P       +    P P  KP+G    GG+    PPPP K          K 
Sbjct: 300 PPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356

Query: 284 SVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQV 343
              ++PP +P  PPQ     PQ    PPP      PQQ   PP  Q Q  P+P       
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQG---PPPPAGGN-PQQPQAPPAGQPQGPPRPPQGGRPS 412

Query: 344 QPQQ 347
           +P Q
Sbjct: 413 RPPQ 416



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 36/113 (31%), Positives = 45/113 (39%), Gaps = 17/113 (15%)

Query: 248 PQPKLKPKGNVGIGGS---AVPPPPIKHNMNIGTWDEKGSVVKAPPT--QPVLPPQTIIQ 302
           P P  KP+G    GG+     PPPP K     G   + G+  + PP   +P  PP    +
Sbjct: 51  PSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---GPPPQGGNKPQGPPPPGKPQGPPPQGDK 107

Query: 303 QPQPLIQP-----PPLVQSQLPQQQPQPP----QPQQQQGPQPQAQPHQVQPQ 346
              P   P     PP      PQ  P PP     P  Q G +PQ  P   +PQ
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 160



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 41/141 (29%), Positives = 48/141 (34%), Gaps = 24/141 (17%)

Query: 226 PPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGS---AVPPPPIKHNMNIGTWDEK 282
           PP     P P        KP  P P  KP+G    GGS   +   PP K          +
Sbjct: 259 PPGKPQGPPPQG----GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314

Query: 283 GSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQ--------------PQPPQP 328
                 PP +P  PP     +PQ    PPP  + Q P  Q              PQ P  
Sbjct: 315 PQGPPPPPGKPQGPPPQGGNKPQG---PPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQ 371

Query: 329 QQQQGPQPQAQPHQVQPQQQQ 349
           Q+   PQ    P    PQQ Q
Sbjct: 372 QEGNNPQGPPPPAGGNPQQPQ 392



 Score = 36.6 bits (83), Expect = 0.066
 Identities = 39/140 (27%), Positives = 54/140 (38%), Gaps = 20/140 (14%)

Query: 220 IATNSVPPVSSAAPKPTSWAAIARKP--AKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIG 277
           +A +S   ++    +  S + IA  P  A PQ   KP+G     G    PPP   N   G
Sbjct: 11  LALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQG 70

Query: 278 TWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQ 337
                      PP +P  PP     +PQ     PP      P  +PQ P PQ  +   P+
Sbjct: 71  P--------PPPPGKPQGPPPQGGNKPQG----PP------PPGKPQGPPPQGDKSRSPR 112

Query: 338 AQPHQVQPQQQQLQNRWVAP 357
           + P + Q    Q  N+   P
Sbjct: 113 SPPGKPQGPPPQGGNQPQGP 132


>gi|162951884 R3H domain containing 2 [Homo sapiens]
          Length = 976

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 43/114 (37%), Positives = 54/114 (47%), Gaps = 15/114 (13%)

Query: 288 APPTQPVLPPQTIIQQPQ-------PLIQPPPLVQSQLPQQQPQPPQPQQ-QQGPQPQAQ 339
           APPTQ VLPPQ  +Q PQ       P  Q P   Q   P   P    PQ+ QQ PQP  Q
Sbjct: 497 APPTQQVLPPQGYMQPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQRGQQLPQPSQQ 556

Query: 340 P--HQVQPQQQQLQNRWV----APRNRGAGFNQNNGAGSENFGLGVVPVSASPS 387
           P    + P QQQ   + +     P+N+G   +Q +  G +  GL VV  +  PS
Sbjct: 557 PGLQPMMPNQQQAAYQGMIGVQQPQNQGLLSSQRSSMGGQMQGL-VVQYTPLPS 609



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 33/123 (26%), Positives = 41/123 (33%), Gaps = 30/123 (24%)

Query: 244 KPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQ 303
           +P   QP L P      GG      P+ ++M              PP Q     Q     
Sbjct: 623 QPPFQQPMLVPVSQSVQGGLPAAGVPVYYSM-------------IPPAQ-----QNGTSP 664

Query: 304 PQPLIQPPPLVQSQLPQQQP--QPPQ-PQQQQGPQPQAQ---------PHQVQPQQQQLQ 351
               +QPP   Q Q+PQ      PPQ PQQ  G  P            P+  QP Q    
Sbjct: 665 SVGFLQPPGSEQYQMPQSPSPCSPPQMPQQYSGVSPSGPGVVVMQLNVPNGPQPPQNPSM 724

Query: 352 NRW 354
            +W
Sbjct: 725 VQW 727


>gi|114431236 zinc finger protein 462 [Homo sapiens]
          Length = 2506

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 34/85 (40%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 270 IKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQ-LPQQQPQPP-- 326
           I  ++N G    + S +    +  +L P    Q PQP   PPP   SQ  P QQPQPP  
Sbjct: 509 ISSSLNEGVVSYESSSINGRKSGVMLDPLQQQQPPQPPPPPPPPPPSQPQPLQQPQPPQL 568

Query: 327 QPQQQQGPQPQAQPHQVQPQQQQLQ 351
           QP  Q  PQPQ QP   Q  Q   Q
Sbjct: 569 QPPHQVPPQPQTQPPPTQQPQPPTQ 593



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 26/54 (48%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 289 PPTQPVLPPQTIIQQPQPL-IQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPH 341
           PP  P   PQ + QQPQP  +QPP  V    PQ Q QPP  QQ Q P   A  H
Sbjct: 549 PPPPPPSQPQPL-QQPQPPQLQPPHQVP---PQPQTQPPPTQQPQPPTQAAPLH 598


>gi|83977459 pleckstrin homology-like domain, family A, member 1
           [Homo sapiens]
          Length = 401

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 32/58 (55%), Positives = 35/58 (60%), Gaps = 4/58 (6%)

Query: 285 VVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQP-PQPQQQQGPQPQAQPH 341
           V + PP+QP   PQ +  QPQP  QP P  QSQ PQ QPQP PQPQQ   P P   PH
Sbjct: 303 VQQQPPSQPQPQPQ-LQPQPQPQPQPQPQPQSQ-PQPQPQPKPQPQQLH-PYPHPHPH 357



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 31/63 (49%), Positives = 38/63 (60%), Gaps = 5/63 (7%)

Query: 292 QPVLPPQTIIQQPQPLIQPPPLVQSQ-LPQQQPQPPQPQQQQGPQPQAQPH---QVQPQQ 347
           Q +L  ++  Q+ Q L+Q  P  Q Q  PQ QPQ PQPQ Q  PQPQ+QP    Q +PQ 
Sbjct: 287 QAILAVKSTRQKQQHLVQQQPPSQPQPQPQLQPQ-PQPQPQPQPQPQSQPQPQPQPKPQP 345

Query: 348 QQL 350
           QQL
Sbjct: 346 QQL 348



 Score = 32.7 bits (73), Expect = 0.95
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 2/43 (4%)

Query: 300 IIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQ--QGPQPQAQP 340
           I+ +   L+ PP  +Q Q  QQQ Q  Q QQQ  QGP   +QP
Sbjct: 173 ILTEEGLLLIPPKQLQHQQQQQQQQQQQQQQQPGQGPAEPSQP 215


>gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
          Length = 1962

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 46/132 (34%), Positives = 60/132 (45%), Gaps = 16/132 (12%)

Query: 315 QSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNNGAGSEN 374
           Q Q  QQQPQ  QPQQQ  PQPQ Q  Q QPQ      R V PR R     Q    G   
Sbjct: 96  QQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQH- 154

Query: 375 FGLGVVPVSAS--PSSVEVHPVLEKLKAINNYNPKDFDWNLKNGRVFIIKSYSEDDIHRS 432
                 PV A+   S+V+V     +  A+ N  P++      NG V    S ++ DI+ S
Sbjct: 155 -----FPVIAANLGSAVKVLNSQSESSALTNQQPQN------NGEV--QNSKNQSDINHS 201

Query: 433 IKYSIWCSTEHG 444
              S + +++ G
Sbjct: 202 TSGSHYENSQRG 213



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 302 QQPQPLIQPPPLVQSQLPQQQPQP-PQPQQQQGPQPQAQPHQ 342
           QQ QP  QP P  Q Q PQQQPQ  P+  ++  P+ + Q H+
Sbjct: 105 QQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHK 146


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 49/141 (34%), Positives = 59/141 (41%), Gaps = 27/141 (19%)

Query: 218 TSIATNSVPPVSSAAPKP----TSWAAIARKPAKPQPKLKPKGNVGIGG--SAVPPPPIK 271
           TSIA    P      P P       A   RK A  QP  +  G+    G  ++VP P   
Sbjct: 362 TSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPK-- 419

Query: 272 HNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQ--PLIQPPPLVQSQ-LPQQQPQPPQP 328
                          +APP+QP+  PQT  +QPQ  P  Q  P  Q+Q LP Q    PQ 
Sbjct: 420 --------------PQAPPSQPL--PQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQH 463

Query: 329 QQQQGPQPQAQPHQVQPQQQQ 349
           QQQ   + Q Q  Q  P QQQ
Sbjct: 464 QQQLFLKQQQQQQQPPPAQQQ 484



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 50/194 (25%), Positives = 68/194 (35%), Gaps = 29/194 (14%)

Query: 182 PGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAI 241
           PGI  I+  +T  K       A  +    A  SS    +  +   P   A P        
Sbjct: 379 PGILPIQPALTPRK------RATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQ 432

Query: 242 ARKP-AKPQPKLKPKGNV-GIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQT 299
           A++P A P P+  P     G+   A   P  +  + +    ++    + PP     P  T
Sbjct: 433 AKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQ----QQPPPAQQQPAGT 488

Query: 300 IIQQPQ----------PLIQPP-----PLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQ 344
             QQ Q          P  Q P     P+V     QQQ      QQQQ  Q Q Q  Q+ 
Sbjct: 489 FYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLA 548

Query: 345 P--QQQQLQNRWVA 356
               QQQL  +  A
Sbjct: 549 TALHQQQLMTQQAA 562



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 2/55 (3%)

Query: 295 LPPQTIIQQPQPLIQPPPLVQSQLPQQQP-QPPQPQQQQGPQPQAQPHQVQPQQQ 348
           L  Q ++ Q   L Q P +   Q PQ QP   PQP   Q P  QA P + QP+ Q
Sbjct: 551 LHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQA-PVRQQPKVQ 604


>gi|31543535 R3H domain containing 1 [Homo sapiens]
          Length = 1099

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 48/168 (28%), Positives = 68/168 (40%), Gaps = 24/168 (14%)

Query: 232 APKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPT 291
           +P+ + +   A  P  P P   P           PPPP+     + T     S    P +
Sbjct: 577 SPQQSGYIMTAAPPPHPPPPPPPPP---------PPPPLPPGQPVPTAGYPAS--GHPVS 625

Query: 292 QPVLPPQTIIQQPQPLIQ----PPPLVQSQLPQQQPQPPQPQQQQGPQPQAQP-----HQ 342
           QPVL  Q  IQQP P +      P    S  PQ +P P         QP  QP     +Q
Sbjct: 626 QPVLQQQGYIQQPSPQMPACYCAPGHYHSSQPQYRPVPSVHYNSHLNQPLPQPAQQTGYQ 685

Query: 343 VQPQQQQLQNRWVA---PRNRGAGFNQNNGAGSENFGLGVVPVSASPS 387
           V P QQQ     V    P+++     Q N  G++  G+ V+P ++ P+
Sbjct: 686 VIPNQQQNYQGIVGVQQPQSQSLVSGQPNSIGNQIQGV-VIPYTSVPT 732



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 55/226 (24%), Positives = 81/226 (35%), Gaps = 29/226 (12%)

Query: 127 FPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGN-----DTLSKV 181
           F  N D S   T+  Q  +     YS     P SS     TD  +   N        S  
Sbjct: 330 FRVNKDASGRSTNSHQSSTENELKYSEPR--PWSS-----TDSDSSLRNLKPAVTKASSF 382

Query: 182 PGISSIEQGMTG--LKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWA 239
            GIS + +G +    K  G L+   +++ G+  SS+G  S     +P   +A  + +  A
Sbjct: 383 SGISVLTRGDSSGSSKSIGRLSKTGSESSGSVGSSTGSLSHIQQPLP--GTALSQSSHGA 440

Query: 240 AIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQT 299
            +          L   G  G+ G    P      + +            PP   ++ PQT
Sbjct: 441 PVVYPTVSTHSSLSFDG--GLNGQVASPSTSFFLLPL-------EAAGIPPGSILINPQT 491

Query: 300 ----IIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPH 341
               I     P++  PP+ Q  +  Q P PPQP     PQ  A  H
Sbjct: 492 GQPFINPDGSPVVYNPPMTQQPVRSQVPGPPQPPLPAPPQQPAANH 537


>gi|55741675 hypothetical protein LOC22889 [Homo sapiens]
          Length = 614

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 55/186 (29%), Positives = 68/186 (36%), Gaps = 27/186 (14%)

Query: 225 VPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPP--PIKHNMNIGTWDEK 282
           V  +++A P P      A     PQP   P      G   VPPP  P++    + +    
Sbjct: 327 VNQINTAVPLPGYTQPSAISSVPPQPPYYPSNGYQSGYPVVPPPQQPVQPPYGVPS-IVP 385

Query: 283 GSVVKAPPTQPVLP---PQTIIQQPQPLIQPPPLVQSQLPQQQP----QPPQPQQQQGPQ 335
            +V  AP   P LP   P    Q P   +QPP     Q P   P     P +     GPQ
Sbjct: 386 PAVSLAPGVLPALPTGVPPVPTQYPITQVQPPAST-GQSPMGGPFIPAAPVKTALPAGPQ 444

Query: 336 PQAQPHQVQPQQQQLQNRWVA---PRNRGAGF-----------NQNNGAGSEN--FGLGV 379
           PQ QP    P Q Q Q R      P  R +G            N   G  S+N   G G 
Sbjct: 445 PQPQPQPPLPSQPQAQKRRFTEELPDERESGLLGYQHGPIHMTNLGTGFSSQNEIEGAGS 504

Query: 380 VPVSAS 385
            P S+S
Sbjct: 505 KPASSS 510


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,063,394
Number of Sequences: 37866
Number of extensions: 1686851
Number of successful extensions: 17750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 272
Number of HSP's successfully gapped in prelim test: 718
Number of HSP's that attempted gapping in prelim test: 8283
Number of HSP's gapped (non-prelim): 5244
length of query: 585
length of database: 18,247,518
effective HSP length: 108
effective length of query: 477
effective length of database: 14,157,990
effective search space: 6753361230
effective search space used: 6753361230
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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