Search of human proteins with 239582755

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239582755 myosin IG [Homo sapiens]
         (1018 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239582755 myosin IG [Homo sapiens]                                2063   0.0  
gi|51100974 myosin ID [Homo sapiens]                                 1241   0.0  
gi|4885503 myosin IA [Homo sapiens]                                   666   0.0  
gi|124494247 myosin IC isoform b [Homo sapiens]                       658   0.0  
gi|124494238 myosin IC isoform a [Homo sapiens]                       658   0.0  
gi|124494240 myosin IC isoform c [Homo sapiens]                       658   0.0  
gi|194328685 myosin IB isoform 1 [Homo sapiens]                       647   0.0  
gi|44889481 myosin IB isoform 2 [Homo sapiens]                        647   0.0  
gi|240120050 myosin IB isoform 1 [Homo sapiens]                       647   0.0  
gi|254028267 myosin 1H [Homo sapiens]                                 612   e-175
gi|55956916 myosin IE [Homo sapiens]                                  531   e-150
gi|27544941 myosin IF [Homo sapiens]                                  507   e-143
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     447   e-125
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     447   e-125
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     447   e-125
gi|118402590 myosin XV [Homo sapiens]                                 444   e-124
gi|154354979 myosin X [Homo sapiens]                                  429   e-120
gi|122937512 myosin VIIB [Homo sapiens]                               426   e-119
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...   419   e-117
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...   419   e-117
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]   418   e-116
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       418   e-116
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       418   e-116
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...   416   e-116
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...   416   e-116
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]    413   e-115
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]          409   e-114
gi|153945715 myosin VC [Homo sapiens]                                 406   e-113
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]          405   e-113
gi|122937345 myosin VB [Homo sapiens]                                 405   e-112

>gi|239582755 myosin IG [Homo sapiens]
          Length = 1018

 Score = 2063 bits (5344), Expect = 0.0
 Identities = 1018/1018 (100%), Positives = 1018/1018 (100%)

Query: 1    MEDEEGPEYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGP 60
            MEDEEGPEYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGP
Sbjct: 1    MEDEEGPEYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGP 60

Query: 61   EAIARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIA 120
            EAIARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIA
Sbjct: 61   EAIARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIA 120

Query: 121  AVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGH 180
            AVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGH
Sbjct: 121  AVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGH 180

Query: 181  IHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMT 240
            IHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMT
Sbjct: 181  IHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMT 240

Query: 241  VHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGL 300
            VHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGL
Sbjct: 241  VHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGL 300

Query: 301  AVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVY 360
            AVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVY
Sbjct: 301  AVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVY 360

Query: 361  QRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQ 420
            QRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQ
Sbjct: 361  QRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQ 420

Query: 421  QLFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITD 480
            QLFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITD
Sbjct: 421  QLFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITD 480

Query: 481  RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF 540
            RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF
Sbjct: 481  RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF 540

Query: 541  QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR 600
            QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR
Sbjct: 541  QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR 600

Query: 601  CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP 660
            CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP
Sbjct: 601  CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP 660

Query: 661  NHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720
            NHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA
Sbjct: 661  NHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720

Query: 721  WRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYGRDLVWPLPPAV 780
            WRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYGRDLVWPLPPAV
Sbjct: 721  WRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYGRDLVWPLPPAV 780

Query: 781  LQPFQDTCHALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDWGCRRAWARDYL 840
            LQPFQDTCHALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDWGCRRAWARDYL
Sbjct: 781  LQPFQDTCHALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDWGCRRAWARDYL 840

Query: 841  SSATDNPTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFHKIRNRALLLTDQHLYKLD 900
            SSATDNPTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFHKIRNRALLLTDQHLYKLD
Sbjct: 841  SSATDNPTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFHKIRNRALLLTDQHLYKLD 900

Query: 901  PDRQYRVMRAVPLEAVTGLSVTSGGDQLVVLHARGQDDLVVCLHRSRPPLDNRVGELVGV 960
            PDRQYRVMRAVPLEAVTGLSVTSGGDQLVVLHARGQDDLVVCLHRSRPPLDNRVGELVGV
Sbjct: 901  PDRQYRVMRAVPLEAVTGLSVTSGGDQLVVLHARGQDDLVVCLHRSRPPLDNRVGELVGV 960

Query: 961  LAAHCQGEGRTLEVRVSDCIPLSHRGVRRLISVEPRPEQPEPDFRCARGSFTLLWPSR 1018
            LAAHCQGEGRTLEVRVSDCIPLSHRGVRRLISVEPRPEQPEPDFRCARGSFTLLWPSR
Sbjct: 961  LAAHCQGEGRTLEVRVSDCIPLSHRGVRRLISVEPRPEQPEPDFRCARGSFTLLWPSR 1018


>gi|51100974 myosin ID [Homo sapiens]
          Length = 1006

 Score = 1241 bits (3210), Expect = 0.0
 Identities = 611/1016 (60%), Positives = 783/1016 (77%), Gaps = 12/1016 (1%)

Query: 1    MEDEEGPEYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGP 60
            M ++E  E+GK DFVL+D V+M +FM NL+LRFEKGRIYT+IGEV+VSVNPY+ L +YG 
Sbjct: 1    MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGR 60

Query: 61   EAIARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIA 120
            + I +Y+GRELYERPPHL+A+A+AAYKAMK RS+DTCIVISGESGAGKTEASK+IMQYIA
Sbjct: 61   DTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIA 120

Query: 121  AVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGH 180
            A+TNPSQRAEVERVK++LLKS CVLEAFGNA+TNRN NSSRFGKYMDINFDFKGDPIGGH
Sbjct: 121  AITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGH 180

Query: 181  IHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMT 240
            I++YLLEKSRV+ Q  GER+FH+FYQLL+G  ++ L  LHL+++ + YN+ H GA L  +
Sbjct: 181  INNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSS 240

Query: 241  VHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGL 300
            ++ A +      + V +AM+VIGF PEE+++V++ILAAILHLGN++FV   +  L + G 
Sbjct: 241  INDAAE-----FRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENG- 294

Query: 301  AVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVY 360
                  +V  +AEL +T  D+V ++LL RTVA+G R++I+K HT  EASY RDA AKA+Y
Sbjct: 295  -----KVVSIIAELLSTKTDMVEKALLYRTVATG-RDIIDKQHTEQEASYGRDAFAKAIY 348

Query: 361  QRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQ 420
            +RLF W+V RIN ++E +  D    GK+TVIGVLDIYGFE+F  NSFEQFCINYCNEKLQ
Sbjct: 349  ERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQ 408

Query: 421  QLFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITD 480
            QLFIQL+LKQEQEEY+REGI W+ ++YFNN  IVDLVE+ H+GI+A+LD+AC + G +TD
Sbjct: 409  QLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTD 468

Query: 481  RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF 540
             +FL+ L+     H H++SR+LC +DK +EF RDFRI+HYAGDV YSV GFIDKN+D LF
Sbjct: 469  EMFLEALNSKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLF 528

Query: 541  QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR 600
            QDFKRL+YNS++P L+ MWP+G+  ITEVTKRPLTA TLFKNSM+ALV+NLASKEP+YVR
Sbjct: 529  QDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVR 588

Query: 601  CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP 660
            CIKPN+ K     D+  CRHQV YLGLLENVRVRRAGFA RQ Y +FL RYKM  E+TWP
Sbjct: 589  CIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWP 648

Query: 661  NHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720
            NH L SDK AV  L+E+ G Q DVA+G +K+FIR+PRTL TLE+ RA+++  IVL LQK 
Sbjct: 649  NHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKV 708

Query: 721  WRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYGRDLVWPLPPAV 780
            WRGTLAR R +R +A  TI+R++RR+KV++++ E+ RRF   +    YG+ + WP PP V
Sbjct: 709  WRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKV 768

Query: 781  LQPFQDTCHALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDWGCRRAWARDYL 840
            L+ F++    +F RWRA QL+K+IP SD+PQ++AKVAA+  L+G R D G +RAW  +YL
Sbjct: 769  LRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYL 828

Query: 841  SSATDNPTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFHKIRNRALLLTDQHLYKLD 900
            +S  D P  S  F      L+ KD +  VLFS HVRKVNRF K+ +RA+ +TD+HLYK+D
Sbjct: 829  ASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMD 888

Query: 901  PDRQYRVMRAVPLEAVTGLSVTSGGDQLVVLHARGQDDLVVCLHRSRPPLDNRVGELVGV 960
            P +QY+VM+ +PL  +TGLSV++G DQLVV H +   DL+VCL   +P  ++R+GELVGV
Sbjct: 889  PTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGV 948

Query: 961  LAAHCQGEGRTLEVRVSDCIPLSHRGVRRLISVEPRPEQPEPDFRCARGSFTLLWP 1016
            L  H + E R L+V V++ +  S  G +  +SVE R  QP+PDF   R  F L  P
Sbjct: 949  LVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVP 1004


>gi|4885503 myosin IA [Homo sapiens]
          Length = 1043

 Score =  666 bits (1718), Expect = 0.0
 Identities = 418/987 (42%), Positives = 567/987 (57%), Gaps = 103/987 (10%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69
           G  D VLL+ +  E  ++NLQLR+E   IYTYIG V++SVNPYQ+LP+YGPE IA+YQ  
Sbjct: 9   GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68

Query: 70  ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129
             YE  PH+YA+AN AY++++ R RD CI+I+GESG+GKTEASK +M Y+AAV    +  
Sbjct: 69  TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE-- 126

Query: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189
           +V  VK+ LL+S  VLEAFGNA+T RN+NSSRFGKYMDI FDFKG P+GG I +YLLEKS
Sbjct: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186

Query: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALD--S 247
           R++KQ  GERNFH FYQLL G++++ L  L LER+   Y      A LN  V S +D   
Sbjct: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGY------AYLNHEV-SRVDGMD 239

Query: 248 DEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFV-ETEEGGLQKEGLAVAEEA 306
           D  S +AV  AM VIGFS EE+  V  + + +L LGN+    E +  G+   G  + +  
Sbjct: 240 DASSFRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASG--IRDGR 297

Query: 307 LVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEW 366
            V  + E+     + V R+L +RT+ +  +E +       +A YARDA AK +Y RLF+W
Sbjct: 298 GVREIGEMVGLNSEEVERALCSRTMET-AKEKVVTALNVMQAQYARDALAKNIYSRLFDW 356

Query: 367 VVNRIN-SVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQ 425
           +VNRIN S+    G       K  V+GVLDIYGFE+   NSFEQF INYCNEKLQQ+FI+
Sbjct: 357 IVNRINESIKVGIGE------KKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIE 410

Query: 426 LILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQ 485
           + LK+EQEEY+REGI W  V+YF+N  I  L+E   RGILA+LDE C   G ++D  FL 
Sbjct: 411 MTLKEEQEEYKREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLA 470

Query: 486 TLDMHHRHHLHYTSRQLCPT----DKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQ 541
            L+     H HY S+         D TM     FRI HYAG VTY+V  FIDKN D LF+
Sbjct: 471 KLNQLFSKHGHYESKVTQNAQRQYDHTMGLS-CFRICHYAGKVTYNVTSFIDKNNDLLFR 529

Query: 542 DFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRC 601
           D  + ++ +  P LR+++P+G      + KRP TAG  FK+S+  L++NL SK P Y+RC
Sbjct: 530 DLLQAMWKAQHPLLRSLFPEGNPKQASL-KRPPTAGAQFKSSVAILMKNLYSKSPNYIRC 588

Query: 602 IKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPN 661
           IKPNE +  G+   +    Q  YLGLLENVRVRRAG+A RQ Y  FL RY++    TWP 
Sbjct: 589 IKPNEHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWP- 647

Query: 662 HLLGSDKAAVSALLEQHGL-QGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720
           H  G D+  V  +L +  +  G++AFG +K+FIRSP+TL  LE+ R   +  +  L+QK 
Sbjct: 648 HWNGGDREGVEKVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKI 707

Query: 721 WRGTLARWRCRRLRAIYTIMR--------WFRRH-------KVRAHLAELQ---RRFQAA 762
           +RG    WRC   R  Y +MR        WFR +       K++A +  +Q   R ++A 
Sbjct: 708 YRG----WRC---RTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKAR 760

Query: 763 RQPPLYGR---------------------------------DLVWPLPP-AVLQPFQDTC 788
           +    Y R                                 D  WP  P   L       
Sbjct: 761 KNYRKYFRSEAALTLADFIYKSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQEL 820

Query: 789 HALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDW--GCRRAWARDYLSSATDN 846
             LF +W+ ++    + P  +  ++ K+ A    +G +  +       +  DY+     N
Sbjct: 821 QQLFYQWKCKRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYI-GLQGN 879

Query: 847 PTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFH-KIRNRALLLTDQHLYKLDPDRQY 905
           P       Q+LK  ++    G VL +  V+KVNR + K  +R LLLT  H+   D  ++ 
Sbjct: 880 PK-----LQKLKGGEE----GPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTD-TKKS 929

Query: 906 RVMRAVPLEAVTGLSVTSGGDQLVVLH 932
           +    + L+ V G+SVTS  D L  LH
Sbjct: 930 QAKIVIGLDNVAGVSVTSLKDGLFSLH 956


>gi|124494247 myosin IC isoform b [Homo sapiens]
          Length = 1044

 Score =  658 bits (1698), Expect = 0.0
 Identities = 409/970 (42%), Positives = 555/970 (57%), Gaps = 71/970 (7%)

Query: 10  GKPDFVLLDQVTMED-FMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           G  DFVLL+  T E  F+ NL+ RF +  IYTYIG VLVSVNPY++L +Y  + + RY+G
Sbjct: 28  GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 87

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
              YE PPHL+AVA+  Y+A++   RD  ++ISGESGAGKTEA+K ++Q+ A      +R
Sbjct: 88  VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 147

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
                V+D LL+S  VLEAFGNA+T RN NSSRFGKYMD+ FDFKG P+GGHI SYLLEK
Sbjct: 148 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 205

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV+ Q+ GERNFH FYQLL G E++ L  L LERNP  Y +  +G    ++  +    D
Sbjct: 206 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSIN----D 261

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
           +   + V +A+ VI F+ +EVE +  I+A++LHLGNI F   EE   Q     V  E  +
Sbjct: 262 KSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQ-----VTTENQL 316

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
            ++  L +     +  +L  R + + G EL+   +   +A+YARDA AKAVY R F W+V
Sbjct: 317 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLE-QAAYARDALAKAVYSRTFTWLV 375

Query: 369 NRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLIL 428
            +IN  +  +  +       TV+G+LDIYGFEVF  NSFEQFCINYCNEKLQQLFI+L L
Sbjct: 376 GKINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTL 435

Query: 429 KQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTLD 488
           K EQEEYE EGI W+ V+YFNN  I DLVE   +GI+++LDE C   G  TD  FL+ L+
Sbjct: 436 KSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLE 495

Query: 489 MHHRHHLHYTSRQLCPTDKTMEFGR-DFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL 547
              +HH H+ + +L         GR +FR+ HYAG+VTYSV GF+DKN D LF++ K  +
Sbjct: 496 DTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETM 555

Query: 548 YNSTDPTLRAMWPDGQQDITEVT--KRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPN 605
            +S +P +   +     D +E++  KRP T  T FK S++ LVE L SKEP YVRCIKPN
Sbjct: 556 CSSKNPIMSQCF-----DRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 610

Query: 606 EDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLLG 665
           + K  G+ DE   RHQV YLGLLEN+RVRRAGFA R+ Y  FL RYK  C  TWP    G
Sbjct: 611 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWA-G 669

Query: 666 SDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLE-------QSRARLIPII---- 713
             +  V+ L+   G + +    G +K+FIR P+TL   E       QS A  I       
Sbjct: 670 RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGF 729

Query: 714 ------------VLLLQKAWRGTLARWRC-RRLRAIYTIMRWFR----RHKVRA-----H 751
                        + +Q  WRGTL R +  +R  A  TI R  R    RH  R       
Sbjct: 730 HWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFF 789

Query: 752 LAELQRRF--QAARQPPLYGRDLVWPLPPAVLQPFQDTCHALFCRWRARQLVKNIPPSDM 809
           L  ++  F     RQ P    D  WP PP  L+   +    L  +    +  ++I P   
Sbjct: 790 LDHVRTSFLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWK 849

Query: 810 PQIKAKVAAMGALQGLRQDWGCRRAWARDYLSSATDNPTASSLFAQRLKTLQDKDGFGAV 869
            Q++ K  A    +G + ++   ++  R ++S+       S    Q L       G   +
Sbjct: 850 QQLQQKAVASEIFKGKKDNY--PQSVPRLFISTRLGTDEISPRVLQAL-------GSEPI 900

Query: 870 LFSSHVRKVNR-FHKIRNRALLLTDQHLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQL 928
            ++  V K +R  +K R+R LLLT   +  ++     +V + +    +TG+SV+S  D L
Sbjct: 901 QYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVE---DAKVKQRIDYANLTGISVSSLSDSL 957

Query: 929 VVLHARGQDD 938
            VLH +  D+
Sbjct: 958 FVLHVQRADN 967


>gi|124494238 myosin IC isoform a [Homo sapiens]
          Length = 1063

 Score =  658 bits (1698), Expect = 0.0
 Identities = 409/970 (42%), Positives = 555/970 (57%), Gaps = 71/970 (7%)

Query: 10  GKPDFVLLDQVTMED-FMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           G  DFVLL+  T E  F+ NL+ RF +  IYTYIG VLVSVNPY++L +Y  + + RY+G
Sbjct: 47  GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
              YE PPHL+AVA+  Y+A++   RD  ++ISGESGAGKTEA+K ++Q+ A      +R
Sbjct: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
                V+D LL+S  VLEAFGNA+T RN NSSRFGKYMD+ FDFKG P+GGHI SYLLEK
Sbjct: 167 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV+ Q+ GERNFH FYQLL G E++ L  L LERNP  Y +  +G    ++  +    D
Sbjct: 225 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSIN----D 280

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
           +   + V +A+ VI F+ +EVE +  I+A++LHLGNI F   EE   Q     V  E  +
Sbjct: 281 KSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQ-----VTTENQL 335

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
            ++  L +     +  +L  R + + G EL+   +   +A+YARDA AKAVY R F W+V
Sbjct: 336 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLE-QAAYARDALAKAVYSRTFTWLV 394

Query: 369 NRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLIL 428
            +IN  +  +  +       TV+G+LDIYGFEVF  NSFEQFCINYCNEKLQQLFI+L L
Sbjct: 395 GKINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTL 454

Query: 429 KQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTLD 488
           K EQEEYE EGI W+ V+YFNN  I DLVE   +GI+++LDE C   G  TD  FL+ L+
Sbjct: 455 KSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLE 514

Query: 489 MHHRHHLHYTSRQLCPTDKTMEFGR-DFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL 547
              +HH H+ + +L         GR +FR+ HYAG+VTYSV GF+DKN D LF++ K  +
Sbjct: 515 DTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETM 574

Query: 548 YNSTDPTLRAMWPDGQQDITEVT--KRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPN 605
            +S +P +   +     D +E++  KRP T  T FK S++ LVE L SKEP YVRCIKPN
Sbjct: 575 CSSKNPIMSQCF-----DRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 629

Query: 606 EDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLLG 665
           + K  G+ DE   RHQV YLGLLEN+RVRRAGFA R+ Y  FL RYK  C  TWP    G
Sbjct: 630 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWA-G 688

Query: 666 SDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLE-------QSRARLIPII---- 713
             +  V+ L+   G + +    G +K+FIR P+TL   E       QS A  I       
Sbjct: 689 RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGF 748

Query: 714 ------------VLLLQKAWRGTLARWRC-RRLRAIYTIMRWFR----RHKVRA-----H 751
                        + +Q  WRGTL R +  +R  A  TI R  R    RH  R       
Sbjct: 749 HWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFF 808

Query: 752 LAELQRRF--QAARQPPLYGRDLVWPLPPAVLQPFQDTCHALFCRWRARQLVKNIPPSDM 809
           L  ++  F     RQ P    D  WP PP  L+   +    L  +    +  ++I P   
Sbjct: 809 LDHVRTSFLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWK 868

Query: 810 PQIKAKVAAMGALQGLRQDWGCRRAWARDYLSSATDNPTASSLFAQRLKTLQDKDGFGAV 869
            Q++ K  A    +G + ++   ++  R ++S+       S    Q L       G   +
Sbjct: 869 QQLQQKAVASEIFKGKKDNY--PQSVPRLFISTRLGTDEISPRVLQAL-------GSEPI 919

Query: 870 LFSSHVRKVNR-FHKIRNRALLLTDQHLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQL 928
            ++  V K +R  +K R+R LLLT   +  ++     +V + +    +TG+SV+S  D L
Sbjct: 920 QYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVE---DAKVKQRIDYANLTGISVSSLSDSL 976

Query: 929 VVLHARGQDD 938
            VLH +  D+
Sbjct: 977 FVLHVQRADN 986


>gi|124494240 myosin IC isoform c [Homo sapiens]
          Length = 1028

 Score =  658 bits (1698), Expect = 0.0
 Identities = 409/970 (42%), Positives = 555/970 (57%), Gaps = 71/970 (7%)

Query: 10  GKPDFVLLDQVTMED-FMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           G  DFVLL+  T E  F+ NL+ RF +  IYTYIG VLVSVNPY++L +Y  + + RY+G
Sbjct: 12  GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 71

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
              YE PPHL+AVA+  Y+A++   RD  ++ISGESGAGKTEA+K ++Q+ A      +R
Sbjct: 72  VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 131

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
                V+D LL+S  VLEAFGNA+T RN NSSRFGKYMD+ FDFKG P+GGHI SYLLEK
Sbjct: 132 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 189

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV+ Q+ GERNFH FYQLL G E++ L  L LERNP  Y +  +G    ++  +    D
Sbjct: 190 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSIN----D 245

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
           +   + V +A+ VI F+ +EVE +  I+A++LHLGNI F   EE   Q     V  E  +
Sbjct: 246 KSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQ-----VTTENQL 300

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
            ++  L +     +  +L  R + + G EL+   +   +A+YARDA AKAVY R F W+V
Sbjct: 301 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLE-QAAYARDALAKAVYSRTFTWLV 359

Query: 369 NRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLIL 428
            +IN  +  +  +       TV+G+LDIYGFEVF  NSFEQFCINYCNEKLQQLFI+L L
Sbjct: 360 GKINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTL 419

Query: 429 KQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTLD 488
           K EQEEYE EGI W+ V+YFNN  I DLVE   +GI+++LDE C   G  TD  FL+ L+
Sbjct: 420 KSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLE 479

Query: 489 MHHRHHLHYTSRQLCPTDKTMEFGR-DFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL 547
              +HH H+ + +L         GR +FR+ HYAG+VTYSV GF+DKN D LF++ K  +
Sbjct: 480 DTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETM 539

Query: 548 YNSTDPTLRAMWPDGQQDITEVT--KRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPN 605
            +S +P +   +     D +E++  KRP T  T FK S++ LVE L SKEP YVRCIKPN
Sbjct: 540 CSSKNPIMSQCF-----DRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 594

Query: 606 EDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLLG 665
           + K  G+ DE   RHQV YLGLLEN+RVRRAGFA R+ Y  FL RYK  C  TWP    G
Sbjct: 595 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWA-G 653

Query: 666 SDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLE-------QSRARLIPII---- 713
             +  V+ L+   G + +    G +K+FIR P+TL   E       QS A  I       
Sbjct: 654 RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGF 713

Query: 714 ------------VLLLQKAWRGTLARWRC-RRLRAIYTIMRWFR----RHKVRA-----H 751
                        + +Q  WRGTL R +  +R  A  TI R  R    RH  R       
Sbjct: 714 HWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFF 773

Query: 752 LAELQRRF--QAARQPPLYGRDLVWPLPPAVLQPFQDTCHALFCRWRARQLVKNIPPSDM 809
           L  ++  F     RQ P    D  WP PP  L+   +    L  +    +  ++I P   
Sbjct: 774 LDHVRTSFLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWK 833

Query: 810 PQIKAKVAAMGALQGLRQDWGCRRAWARDYLSSATDNPTASSLFAQRLKTLQDKDGFGAV 869
            Q++ K  A    +G + ++   ++  R ++S+       S    Q L       G   +
Sbjct: 834 QQLQQKAVASEIFKGKKDNY--PQSVPRLFISTRLGTDEISPRVLQAL-------GSEPI 884

Query: 870 LFSSHVRKVNR-FHKIRNRALLLTDQHLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQL 928
            ++  V K +R  +K R+R LLLT   +  ++     +V + +    +TG+SV+S  D L
Sbjct: 885 QYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVE---DAKVKQRIDYANLTGISVSSLSDSL 941

Query: 929 VVLHARGQDD 938
            VLH +  D+
Sbjct: 942 FVLHVQRADN 951


>gi|194328685 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  647 bits (1669), Expect = 0.0
 Identities = 359/772 (46%), Positives = 493/772 (63%), Gaps = 46/772 (5%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69
           G  D VLL+ +  E F+ NL+ RF+   IYTYIG V++SVNPY+ LP+Y PE +  Y+ R
Sbjct: 16  GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75

Query: 70  ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129
             YE  PH++A+++ AY++++ + +D CI+I+GESGAGKTEASK +M Y+AAV      A
Sbjct: 76  NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133

Query: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189
           EV +VK+ LL+S  VLEAFGNA+T RN NSSRFGKYMDI FDFKGDP+GG I +YLLEKS
Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193

Query: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSDE 249
           RV+KQ  GERNFH FYQLL G+ ++ L++L LER+ + YN+      L+    + +D D 
Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYL----SLDSAKVNGVD-DA 248

Query: 250 QSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFV-ETEEGGLQKEGLAVAEEALV 308
            + + V  AM+++GF   E ESV  ++AA+L LGNIEF  E+   GL +  +    E  +
Sbjct: 249 ANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNE--L 306

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
             + ELT   + ++ R+   RTV +  +E +      A+A YARDA AK +Y RLF W+V
Sbjct: 307 KEICELTGIDQSVLERAFSFRTVEAK-QEKVSTTLNVAQAYYARDALAKNLYSRLFSWLV 365

Query: 369 NRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLIL 428
           NRIN  ++ + +  ++     V+GVLDIYGFE+F  NSFEQF INYCNEKLQQ+FI+L L
Sbjct: 366 NRINESIKAQTKVRKK-----VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTL 420

Query: 429 KQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTLD 488
           K+EQEEY RE I W  ++YFNNA I DL+E    GILA+LDE C   GT+TD  FL+ L+
Sbjct: 421 KEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLN 480

Query: 489 MHHRHHLHYTSRQLCPTDKTMEFGRD-------FRIKHYAGDVTYSVEGFIDKNRDFLFQ 541
                H H+ SR      K   F  D       FRI+HYAG V Y VEGF+DKN D L++
Sbjct: 481 QVCATHQHFESRM----SKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYR 536

Query: 542 DFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRC 601
           D  + ++ ++   +++++P+G      + KRP TAG+ FK S+  L++NL +K P Y+RC
Sbjct: 537 DLSQAMWKASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRC 595

Query: 602 IKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPN 661
           IKPN+ K A   +E    HQ+ YLGLLENVRVRRAG+A RQ Y   L RYKM C+ TWP 
Sbjct: 596 IKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWP- 654

Query: 662 HLLGSDKAAVSALLEQHGLQ-GDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720
           H  G  ++ V  L  +  +   + +FG SK+FIR+PRTL  LE  R + +  +  L+QK 
Sbjct: 655 HWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKI 714

Query: 721 WRGTLARWRCR-----RLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPL 767
           +RG    W+CR       ++   I  W+RR+         Q+R+Q  +   L
Sbjct: 715 YRG----WKCRTHFLLMKKSQIVIAAWYRRY-------AQQKRYQQTKSSAL 755



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 2/67 (2%)

Query: 869  VLFSSHVRKVNRFH-KIRNRALLLTDQHLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQ 927
            ++ +  V K+NR + K  +R  LLT+ +L   D  +  ++   VPL  VT +S++S  D 
Sbjct: 987  IIIAEVVNKINRANGKSTSRIFLLTNNNLLLAD-QKSGQIKSEVPLVDVTKVSMSSQNDG 1045

Query: 928  LVVLHAR 934
               +H +
Sbjct: 1046 FFAVHLK 1052


>gi|44889481 myosin IB isoform 2 [Homo sapiens]
          Length = 1078

 Score =  647 bits (1669), Expect = 0.0
 Identities = 359/772 (46%), Positives = 493/772 (63%), Gaps = 46/772 (5%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69
           G  D VLL+ +  E F+ NL+ RF+   IYTYIG V++SVNPY+ LP+Y PE +  Y+ R
Sbjct: 16  GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75

Query: 70  ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129
             YE  PH++A+++ AY++++ + +D CI+I+GESGAGKTEASK +M Y+AAV      A
Sbjct: 76  NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133

Query: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189
           EV +VK+ LL+S  VLEAFGNA+T RN NSSRFGKYMDI FDFKGDP+GG I +YLLEKS
Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193

Query: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSDE 249
           RV+KQ  GERNFH FYQLL G+ ++ L++L LER+ + YN+      L+    + +D D 
Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYL----SLDSAKVNGVD-DA 248

Query: 250 QSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFV-ETEEGGLQKEGLAVAEEALV 308
            + + V  AM+++GF   E ESV  ++AA+L LGNIEF  E+   GL +  +    E  +
Sbjct: 249 ANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNE--L 306

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
             + ELT   + ++ R+   RTV +  +E +      A+A YARDA AK +Y RLF W+V
Sbjct: 307 KEICELTGIDQSVLERAFSFRTVEAK-QEKVSTTLNVAQAYYARDALAKNLYSRLFSWLV 365

Query: 369 NRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLIL 428
           NRIN  ++ + +  ++     V+GVLDIYGFE+F  NSFEQF INYCNEKLQQ+FI+L L
Sbjct: 366 NRINESIKAQTKVRKK-----VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTL 420

Query: 429 KQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTLD 488
           K+EQEEY RE I W  ++YFNNA I DL+E    GILA+LDE C   GT+TD  FL+ L+
Sbjct: 421 KEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLN 480

Query: 489 MHHRHHLHYTSRQLCPTDKTMEFGRD-------FRIKHYAGDVTYSVEGFIDKNRDFLFQ 541
                H H+ SR      K   F  D       FRI+HYAG V Y VEGF+DKN D L++
Sbjct: 481 QVCATHQHFESRM----SKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYR 536

Query: 542 DFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRC 601
           D  + ++ ++   +++++P+G      + KRP TAG+ FK S+  L++NL +K P Y+RC
Sbjct: 537 DLSQAMWKASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRC 595

Query: 602 IKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPN 661
           IKPN+ K A   +E    HQ+ YLGLLENVRVRRAG+A RQ Y   L RYKM C+ TWP 
Sbjct: 596 IKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWP- 654

Query: 662 HLLGSDKAAVSALLEQHGLQ-GDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720
           H  G  ++ V  L  +  +   + +FG SK+FIR+PRTL  LE  R + +  +  L+QK 
Sbjct: 655 HWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKI 714

Query: 721 WRGTLARWRCR-----RLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPL 767
           +RG    W+CR       ++   I  W+RR+         Q+R+Q  +   L
Sbjct: 715 YRG----WKCRTHFLLMKKSQIVIAAWYRRY-------AQQKRYQQTKSSAL 755


>gi|240120050 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  647 bits (1669), Expect = 0.0
 Identities = 359/772 (46%), Positives = 493/772 (63%), Gaps = 46/772 (5%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69
           G  D VLL+ +  E F+ NL+ RF+   IYTYIG V++SVNPY+ LP+Y PE +  Y+ R
Sbjct: 16  GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75

Query: 70  ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129
             YE  PH++A+++ AY++++ + +D CI+I+GESGAGKTEASK +M Y+AAV      A
Sbjct: 76  NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKG--A 133

Query: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189
           EV +VK+ LL+S  VLEAFGNA+T RN NSSRFGKYMDI FDFKGDP+GG I +YLLEKS
Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193

Query: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSDE 249
           RV+KQ  GERNFH FYQLL G+ ++ L++L LER+ + YN+      L+    + +D D 
Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYL----SLDSAKVNGVD-DA 248

Query: 250 QSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFV-ETEEGGLQKEGLAVAEEALV 308
            + + V  AM+++GF   E ESV  ++AA+L LGNIEF  E+   GL +  +    E  +
Sbjct: 249 ANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNE--L 306

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
             + ELT   + ++ R+   RTV +  +E +      A+A YARDA AK +Y RLF W+V
Sbjct: 307 KEICELTGIDQSVLERAFSFRTVEAK-QEKVSTTLNVAQAYYARDALAKNLYSRLFSWLV 365

Query: 369 NRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLIL 428
           NRIN  ++ + +  ++     V+GVLDIYGFE+F  NSFEQF INYCNEKLQQ+FI+L L
Sbjct: 366 NRINESIKAQTKVRKK-----VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTL 420

Query: 429 KQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTLD 488
           K+EQEEY RE I W  ++YFNNA I DL+E    GILA+LDE C   GT+TD  FL+ L+
Sbjct: 421 KEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLN 480

Query: 489 MHHRHHLHYTSRQLCPTDKTMEFGRD-------FRIKHYAGDVTYSVEGFIDKNRDFLFQ 541
                H H+ SR      K   F  D       FRI+HYAG V Y VEGF+DKN D L++
Sbjct: 481 QVCATHQHFESRM----SKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYR 536

Query: 542 DFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRC 601
           D  + ++ ++   +++++P+G      + KRP TAG+ FK S+  L++NL +K P Y+RC
Sbjct: 537 DLSQAMWKASHALIKSLFPEGNPAKINL-KRPPTAGSQFKASVATLMKNLQTKNPNYIRC 595

Query: 602 IKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPN 661
           IKPN+ K A   +E    HQ+ YLGLLENVRVRRAG+A RQ Y   L RYKM C+ TWP 
Sbjct: 596 IKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWP- 654

Query: 662 HLLGSDKAAVSALLEQHGLQ-GDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720
           H  G  ++ V  L  +  +   + +FG SK+FIR+PRTL  LE  R + +  +  L+QK 
Sbjct: 655 HWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKI 714

Query: 721 WRGTLARWRCR-----RLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPL 767
           +RG    W+CR       ++   I  W+RR+         Q+R+Q  +   L
Sbjct: 715 YRG----WKCRTHFLLMKKSQIVIAAWYRRY-------AQQKRYQQTKSSAL 755



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 2/67 (2%)

Query: 869  VLFSSHVRKVNRFH-KIRNRALLLTDQHLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQ 927
            ++ +  V K+NR + K  +R  LLT+ +L   D  +  ++   VPL  VT +S++S  D 
Sbjct: 987  IIIAEVVNKINRANGKSTSRIFLLTNNNLLLAD-QKSGQIKSEVPLVDVTKVSMSSQNDG 1045

Query: 928  LVVLHAR 934
               +H +
Sbjct: 1046 FFAVHLK 1052


>gi|254028267 myosin 1H [Homo sapiens]
          Length = 1022

 Score =  612 bits (1577), Expect = e-175
 Identities = 384/969 (39%), Positives = 543/969 (56%), Gaps = 76/969 (7%)

Query: 10  GKPDFVLLDQVTMED-FMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           G  DFVLLD  T E  F+ NL+ RF +  IYTYIG +LVSVNPYQEL +Y    +  YQG
Sbjct: 12  GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
              +E PPH+YA+A+ AY+ M     +  I+ISGESGAGKTEASK I++Y A     +Q 
Sbjct: 72  VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
            ++ R  D LL S  VLEAFGNART RN NSSRFGKYMDI FDF+G P+GGHI SYL+EK
Sbjct: 132 LQIAR--DRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDS- 247
           SRV+ Q+ GERNFH FYQLL G E+++L  L LER+P +Y +  QG       H A +S 
Sbjct: 190 SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQG-------HCAKESS 242

Query: 248 --DEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEE 305
             D+   + V+ A  VI F+  ++E++  I+A++LHLGNI F E ++G        + + 
Sbjct: 243 ISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCA-----TIPDT 297

Query: 306 ALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFE 365
             +  +A+L      ++L +L  R + +   E+I    T   + YARDA AKAVY R F 
Sbjct: 298 HEIKWIAKLLGVHPSVLLEALTHRKIEAKTEEVICP-LTLELSVYARDAMAKAVYGRTFT 356

Query: 366 WVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQ 425
           W+VN+INS +  +        + TVIG+LDIYGFEVF  N FEQFCINYCNEKLQQL I+
Sbjct: 357 WLVNKINSSLVNKDFT-----RKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIE 411

Query: 426 LILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQ 485
             LK EQ EYE EGI W+ ++YFNN  I DLVE  H+GI+++LDE C   G  TD  FL+
Sbjct: 412 RTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLE 471

Query: 486 TLDMHHRHHLHYTSRQLCPTDKTMEFG-RDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFK 544
            L+     H H+ +R+L         G  +FR+ HYAG+VTY  +GF++KN D L++  K
Sbjct: 472 KLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLK 531

Query: 545 RLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRCIKP 604
            +L  S +  LR  +   +    E  +RP T GT FKNS+ +L+E L SKEP Y+RCIKP
Sbjct: 532 EVLCKSKNIILRECFLLAE---LENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKP 588

Query: 605 NEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLL 664
           N+ K   K D+   RHQ+ YLGL+E++RVRRAGFA R+ Y  FL RYK  C  TWP H  
Sbjct: 589 NDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWP-HWH 647

Query: 665 GSDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLEQ----SRARLIPII------ 713
           G     V  L++  G + +    G +K+FIR PRTL   E     S+ +L+  I      
Sbjct: 648 GPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKR 707

Query: 714 -------------VLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRHKVRAH--------- 751
                         + L+  WRG LAR   +R +    I+R F +  +  +         
Sbjct: 708 CLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEE 767

Query: 752 -LAELQRRF--QAARQPPLYGRDLVWPLPPAVLQPFQDTCHALFCRWRARQLVKNIPPSD 808
            +  +++ +        P    D  W  PP +L+   D    +  R   ++  + I    
Sbjct: 768 FIVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAER 827

Query: 809 MPQIKAKVAAMGALQGLRQDWGCRRAWARDYLSSATDNPTASSLFAQRLKTLQDKDGFGA 868
              ++ KV      +G R+D G   +  + +++S  D    +    Q +    +K  +G 
Sbjct: 828 KAMMQQKVVTSEIFRG-RKD-GYTESLNQPFVNSRIDEGDINPKVLQLIS--HEKIQYGV 883

Query: 869 VLFSSHVRKVNRFHKIRNRALLLTDQHLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQL 928
            +    ++   +  K R R L+LT +  Y ++     ++ + +   A+ G+S ++  D +
Sbjct: 884 PV----IKYDRKGFKARQRQLILTQKAAYVVE---LAKIKQKIEYSALKGVSTSNLSDGI 936

Query: 929 VVLHARGQD 937
           +V+H   +D
Sbjct: 937 LVIHVSPED 945


>gi|55956916 myosin IE [Homo sapiens]
          Length = 1108

 Score =  531 bits (1367), Expect = e-150
 Identities = 306/734 (41%), Positives = 432/734 (58%), Gaps = 43/734 (5%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69
           G  D VLL ++T    + NL+ R+    I+TYIG VL+SVNP++++P +G + I  YQG 
Sbjct: 20  GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79

Query: 70  ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129
             YE PPH+YA+A+  Y+ M     + C++ISGESGAGKT A+K+IM YI+ V+      
Sbjct: 80  AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGG--T 137

Query: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189
           +V+ VKD++L+S  +LEAFGNA+T RN+NSSRFGKY +I F   G+P GG I ++LLEKS
Sbjct: 138 KVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKS 197

Query: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSDE 249
           RV+ ++ GER+FH FYQL+ G+  +Q H L +      Y  +  G+     +      D 
Sbjct: 198 RVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDI-----DDR 252

Query: 250 QSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALVD 309
           +  Q    AM VIG   EE   V +I+A ILHLGNI F E           AV  E  + 
Sbjct: 253 REFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYA------AVESEEFLA 306

Query: 310 HVAELTATPRDLVLRSLLARTVAS---GGRELIEKGHTAAEASYARDACAKAVYQRLFEW 366
             A L    +D +   L +R + S   G  E I       +A Y RDA AKA++ R+F++
Sbjct: 307 FPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDF 366

Query: 367 VVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQL 426
           +V+ IN  ME       +D ++  IGVLDIYGFE+F  N FEQFCIN+ NEKLQQ+FI+L
Sbjct: 367 LVDSINKAME-------KDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIEL 419

Query: 427 ILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHR--GILAVLDEACS---SAGTITDR 481
            LK EQEEY +EGI W  +EYFNN  + DL+E      GI+++LD+ C+   + G   D+
Sbjct: 420 TLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQ 479

Query: 482 IFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQ 541
             LQ L M    H H+ S           + + F I HYAG V+Y ++GF ++NRD LF 
Sbjct: 480 TLLQKLQMQIGSHEHFNS-----------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFM 528

Query: 542 DFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRC 601
           D   L+ +S  P +++++P+  Q   +   RP TAG+  K     LV  L    P Y+RC
Sbjct: 529 DLIELMQSSELPFIKSLFPENLQ--ADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRC 586

Query: 602 IKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPN 661
           IKPNE K     +E+  +HQV YLGL EN+RVRRAG+A R+ + +FL RY +  + TWP+
Sbjct: 587 IKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPS 646

Query: 662 HLLGSDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKA 720
              G +K  V  LL+   +  D    G SK+FI++P +L  LE+ R R       ++QK+
Sbjct: 647 -WQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKS 705

Query: 721 WRGTLARWRCRRLR 734
           WR  +AR +  ++R
Sbjct: 706 WRKFVARKKYVQMR 719


>gi|27544941 myosin IF [Homo sapiens]
          Length = 1098

 Score =  507 bits (1306), Expect = e-143
 Identities = 306/735 (41%), Positives = 422/735 (57%), Gaps = 45/735 (6%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69
           G  D VLL Q+T +    NL+ RF    I+TYIG VL+SVNP++++P +    I  YQG 
Sbjct: 18  GVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQGA 77

Query: 70  ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129
             YE PPH+YA+ +  Y+ M     + C++ISGESGAGKT A+K+IM YI+ V+   ++ 
Sbjct: 78  AQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK- 136

Query: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189
            V+ VKD++L+S  +LEAFGNA+T RN+NSSRFGKY +I F   G+P GG I ++LLEKS
Sbjct: 137 -VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195

Query: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSDE 249
           RV+ Q+  ERNFH +YQLL G+  +Q   L L   P  Y + +Q        +    +D+
Sbjct: 196 RVVMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQS-----DTYQVDGTDD 249

Query: 250 QSHQAVT-EAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
           +S    T  AM+VIG  P   + V +++A ILHLGNI F   E+G   +    V    L+
Sbjct: 250 RSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISF--CEDGNYAR----VESVDLL 303

Query: 309 DHVAELTATPRDLVLRSLLARTVAS--GGR-ELIEKGHTAAEASYARDACAKAVYQRLFE 365
              A L       +   L +R + S  GGR E I       +A+Y RDA AK +Y RLF+
Sbjct: 304 AFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFD 363

Query: 366 WVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQ 425
           ++V  IN  M+       +  ++  IGVLDIYGFE+F  N FEQFCIN+ NEKLQQ+FI+
Sbjct: 364 FLVEAINRAMQ-------KPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIE 416

Query: 426 LILKQEQEEYEREGITWQSVEYFNNATIVDLVER--PHRGILAVLDEACS---SAGTITD 480
           L LK EQEEY +EGI W  ++YFNN  + DL+E      GI++VLD+ C+   + G   D
Sbjct: 417 LTLKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGAD 476

Query: 481 RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF 540
           +  LQ L      H H+ S           +   F I HYAG V+Y V GF ++NRD LF
Sbjct: 477 QTLLQKLQAAVGTHEHFNS-----------WSAGFVIHHYAGKVSYDVSGFCERNRDVLF 525

Query: 541 QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR 600
            D   L+  S    LR ++P+      +   RP TAG+  K     LV  L    P Y+R
Sbjct: 526 SDLIELMQTSEQAFLRMLFPEKLDG--DKKGRPSTAGSKIKKQANDLVATLMRCTPHYIR 583

Query: 601 CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP 660
           CIKPNE K     +EN  +HQV YLGL EN+RVRRAGFA R+ +++FL RY +    TWP
Sbjct: 584 CIKPNETKRPRDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWP 643

Query: 661 NHLLGSDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQK 719
               G ++  V  LL    ++ D    G +K+F+++P +L  LE+ R R        +QK
Sbjct: 644 -RWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQK 702

Query: 720 AWRGTLARWRCRRLR 734
           AWR  +A  +   +R
Sbjct: 703 AWRRHVAVRKYEEMR 717


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  447 bits (1151), Expect = e-125
 Identities = 275/754 (36%), Positives = 425/754 (56%), Gaps = 27/754 (3%)

Query: 9   YGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           +G  D + L  +     +RNL +R+    IYTY G +LV+VNPYQ L +Y PE I +Y  
Sbjct: 65  HGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
           +++ E PPH++A+A+  Y  MK  SRD C +ISGESGAGKTE++K I+Q++AA++   Q 
Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQH 182

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
           + +E+    +L++T +LEAFGNA+T RN NSSRFGKY+DI+F+ +G   G  I  YLLEK
Sbjct: 183 SWIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEK 239

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV +Q + ERN+H FY +L G  + Q  +L L +     ++ +   G  +T    +DS 
Sbjct: 240 SRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ---ASDYNYLAMGNCITCEGRVDSQ 296

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
           E ++  +  AM+V+ F+  E   + ++LAAILHLGN+++       L    + +   +L 
Sbjct: 297 EYAN--IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEV-LFSPSLA 353

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
              + L   P DL +  L +RT+ + G E +    +  +A   RDA  K +Y RLF W+V
Sbjct: 354 TAASLLEVNPPDL-MSCLTSRTLITRG-ETVSTPLSREQALDVRDAFVKGIYGRLFVWIV 411

Query: 369 NRIN-SVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLI 427
           ++IN ++ +P  +D +   +   IG+LDI+GFE F VNSFEQ CIN+ NE LQQ F++ +
Sbjct: 412 DKINAAIYKPPSQDVKNSRRS--IGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469

Query: 428 LKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTL 487
            K EQEEY+ E I W  +E+ +N   +D++      I++++DE  S     TD   L  L
Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEE-SKFPKGTDTTMLHKL 528

Query: 488 DMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL 547
           +  H+ + +Y      P     E    F I H+AG V Y  +GF++KNRD L  D  +L+
Sbjct: 529 NSQHKLNANY-----IPPKNNHE--TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLV 581

Query: 548 YNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPNED 607
           ++S +  ++ ++        E  KR  T  + FK S+  L+  L + +PF+VRCIKPNE 
Sbjct: 582 HSSRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEF 641

Query: 608 KVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLLGSD 667
           K     D + C  Q+ Y G++E +R+RRAG+  R  +  F+ RY++      P +  G  
Sbjct: 642 KKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDL 701

Query: 668 KAAVSALLEQ-HGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKAWRGTLA 726
           +     + E   G   D   G +K+F++    ++ LE  R + I   V+LLQK  RG   
Sbjct: 702 RGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKD 760

Query: 727 RWRCRRLR-AIYTIMRWFRRHKVRAHLAELQRRF 759
           R    +L+ A   I R +R H  R +   ++  F
Sbjct: 761 RSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGF 794


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  447 bits (1151), Expect = e-125
 Identities = 275/754 (36%), Positives = 425/754 (56%), Gaps = 27/754 (3%)

Query: 9   YGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           +G  D + L  +     +RNL +R+    IYTY G +LV+VNPYQ L +Y PE I +Y  
Sbjct: 65  HGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
           +++ E PPH++A+A+  Y  MK  SRD C +ISGESGAGKTE++K I+Q++AA++   Q 
Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQH 182

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
           + +E+    +L++T +LEAFGNA+T RN NSSRFGKY+DI+F+ +G   G  I  YLLEK
Sbjct: 183 SWIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEK 239

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV +Q + ERN+H FY +L G  + Q  +L L +     ++ +   G  +T    +DS 
Sbjct: 240 SRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ---ASDYNYLAMGNCITCEGRVDSQ 296

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
           E ++  +  AM+V+ F+  E   + ++LAAILHLGN+++       L    + +   +L 
Sbjct: 297 EYAN--IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEV-LFSPSLA 353

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
              + L   P DL +  L +RT+ + G E +    +  +A   RDA  K +Y RLF W+V
Sbjct: 354 TAASLLEVNPPDL-MSCLTSRTLITRG-ETVSTPLSREQALDVRDAFVKGIYGRLFVWIV 411

Query: 369 NRIN-SVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLI 427
           ++IN ++ +P  +D +   +   IG+LDI+GFE F VNSFEQ CIN+ NE LQQ F++ +
Sbjct: 412 DKINAAIYKPPSQDVKNSRRS--IGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469

Query: 428 LKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTL 487
            K EQEEY+ E I W  +E+ +N   +D++      I++++DE  S     TD   L  L
Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEE-SKFPKGTDTTMLHKL 528

Query: 488 DMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL 547
           +  H+ + +Y      P     E    F I H+AG V Y  +GF++KNRD L  D  +L+
Sbjct: 529 NSQHKLNANY-----IPPKNNHE--TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLV 581

Query: 548 YNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPNED 607
           ++S +  ++ ++        E  KR  T  + FK S+  L+  L + +PF+VRCIKPNE 
Sbjct: 582 HSSRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEF 641

Query: 608 KVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLLGSD 667
           K     D + C  Q+ Y G++E +R+RRAG+  R  +  F+ RY++      P +  G  
Sbjct: 642 KKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDL 701

Query: 668 KAAVSALLEQ-HGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKAWRGTLA 726
           +     + E   G   D   G +K+F++    ++ LE  R + I   V+LLQK  RG   
Sbjct: 702 RGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKD 760

Query: 727 RWRCRRLR-AIYTIMRWFRRHKVRAHLAELQRRF 759
           R    +L+ A   I R +R H  R +   ++  F
Sbjct: 761 RSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGF 794


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  447 bits (1151), Expect = e-125
 Identities = 275/754 (36%), Positives = 425/754 (56%), Gaps = 27/754 (3%)

Query: 9   YGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           +G  D + L  +     +RNL +R+    IYTY G +LV+VNPYQ L +Y PE I +Y  
Sbjct: 65  HGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
           +++ E PPH++A+A+  Y  MK  SRD C +ISGESGAGKTE++K I+Q++AA++   Q 
Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQH 182

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
           + +E+    +L++T +LEAFGNA+T RN NSSRFGKY+DI+F+ +G   G  I  YLLEK
Sbjct: 183 SWIEQ---QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEK 239

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV +Q + ERN+H FY +L G  + Q  +L L +     ++ +   G  +T    +DS 
Sbjct: 240 SRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ---ASDYNYLAMGNCITCEGRVDSQ 296

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
           E ++  +  AM+V+ F+  E   + ++LAAILHLGN+++       L    + +   +L 
Sbjct: 297 EYAN--IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEV-LFSPSLA 353

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
              + L   P DL +  L +RT+ + G E +    +  +A   RDA  K +Y RLF W+V
Sbjct: 354 TAASLLEVNPPDL-MSCLTSRTLITRG-ETVSTPLSREQALDVRDAFVKGIYGRLFVWIV 411

Query: 369 NRIN-SVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLI 427
           ++IN ++ +P  +D +   +   IG+LDI+GFE F VNSFEQ CIN+ NE LQQ F++ +
Sbjct: 412 DKINAAIYKPPSQDVKNSRRS--IGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469

Query: 428 LKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTL 487
            K EQEEY+ E I W  +E+ +N   +D++      I++++DE  S     TD   L  L
Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEE-SKFPKGTDTTMLHKL 528

Query: 488 DMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL 547
           +  H+ + +Y      P     E    F I H+AG V Y  +GF++KNRD L  D  +L+
Sbjct: 529 NSQHKLNANY-----IPPKNNHE--TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLV 581

Query: 548 YNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPNED 607
           ++S +  ++ ++        E  KR  T  + FK S+  L+  L + +PF+VRCIKPNE 
Sbjct: 582 HSSRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEF 641

Query: 608 KVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLLGSD 667
           K     D + C  Q+ Y G++E +R+RRAG+  R  +  F+ RY++      P +  G  
Sbjct: 642 KKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDL 701

Query: 668 KAAVSALLEQ-HGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKAWRGTLA 726
           +     + E   G   D   G +K+F++    ++ LE  R + I   V+LLQK  RG   
Sbjct: 702 RGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVERDKAITDRVILLQKVIRGFKD 760

Query: 727 RWRCRRLR-AIYTIMRWFRRHKVRAHLAELQRRF 759
           R    +L+ A   I R +R H  R +   ++  F
Sbjct: 761 RSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGF 794


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score =  444 bits (1141), Expect = e-124
 Identities = 296/784 (37%), Positives = 426/784 (54%), Gaps = 55/784 (7%)

Query: 4    EEGPEYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAI 63
            E+  E G  D   L+ +     + NL++RFE+  IYTYIG +LVSVNPYQ   +YGPE +
Sbjct: 1217 EQHGEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQV 1276

Query: 64   ARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVT 123
             +Y GR L E PPHL+AVAN A+  M    ++ CI+ISGESG+GKTEA+K I++Y+AA+ 
Sbjct: 1277 QQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMN 1336

Query: 124  NPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHS 183
               +R  ++++K  +L++T +LE+FGNA+T RN NSSRFGK+++I  +  G  I G I S
Sbjct: 1337 --QKREVMQQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE--GGVISGAITS 1390

Query: 184  -YLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVH 242
             YLLEKSR++ Q   ERN+H FY+LL G    QL +    +    Y + +QG    +   
Sbjct: 1391 QYLLEKSRIVFQAKNERNYHIFYELLAGL-PAQLRQAFSLQEAETYYYLNQGGNCEI--- 1446

Query: 243  SALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAV 302
             A  SD    + +  AM V+GFS E+ +S+ RILA+ILHLGN+ F + E    +   +  
Sbjct: 1447 -AGKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVS 1505

Query: 303  AEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQR 362
            A E  +  VAEL     +  L+  +   V    RE I    T   A  ARDA AK +Y  
Sbjct: 1506 ARE--IQAVAELLQISPE-GLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYAL 1562

Query: 363  LFEWVVNRINSVMEPRGRDPRRDGKDTV-IGVLDIYGFEVFPVNSFEQFCINYCNEKLQQ 421
            LF W++ R+N+++ PR        +DT+ I +LDIYGFE    NSFEQ CINY NE LQ 
Sbjct: 1563 LFSWLITRVNALVSPR--------QDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQY 1614

Query: 422  LFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDR 481
            LF +++ ++EQEEY RE I WQ + + +N   ++L+     GIL +LD+ C      TD 
Sbjct: 1615 LFNKIVFQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDH 1673

Query: 482  IFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQ 541
             FLQ    HH  +  Y S+   P         +F IKHYAG VTY V  F+DKN D + Q
Sbjct: 1674 TFLQKCHYHHGANPLY-SKPKMPLP-------EFTIKHYAGKVTYQVHKFLDKNHDQVRQ 1725

Query: 542  DFKRL-----------LYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVEN 590
            D   L           L++S  P            +T + K   T    F+ S++ LVE 
Sbjct: 1726 DVLDLFVRSRTRVVAHLFSSHAPQAAPQRLGKSSSVTRLYKAH-TVAAKFQQSLLDLVEK 1784

Query: 591  LASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLR 650
            +    P ++RC+KPN  K  G  + +    Q+ Y G+LE VR+R+ GF  R P+  F+ R
Sbjct: 1785 MERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDR 1844

Query: 651  YKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDV-AFGHSKLFIRSPRTLVTLEQSRARL 709
            Y   C     + L  +    VS L     +  ++   G SKLF++       LE  R  +
Sbjct: 1845 Y--CCLVALKHDLPANGDMCVSVLSRLCKVMPNMYRVGVSKLFLKE-HLYQLLESMREHV 1901

Query: 710  IPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYG 769
            + +  L LQ+  RG   + R R LR    ++    + + R +LA  ++R+Q  R+  +  
Sbjct: 1902 LNLAALTLQRCLRGFFIKRRFRSLRHKIILL----QSRARGYLA--RQRYQQMRRSLVKF 1955

Query: 770  RDLV 773
            R LV
Sbjct: 1956 RSLV 1959


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  429 bits (1104), Expect = e-120
 Identities = 278/765 (36%), Positives = 428/765 (55%), Gaps = 51/765 (6%)

Query: 8   EYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELP-LYGPEAIARY 66
           E G  D   L ++     M NL  R+++ +IYTYIG +L SVNPYQ +  LY P  + +Y
Sbjct: 62  EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY 121

Query: 67  QGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPS 126
             R L E PPH++A+AN  Y+ +  R  + CI+ISGESGAGKTE++K I+++++ ++  S
Sbjct: 122 SRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQS 181

Query: 127 QRAEVER----VKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIH 182
               ++     V+  +L+S+ ++EAFGNA+T  N+NSSRFGK++ +N   KG+  GG I 
Sbjct: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241

Query: 183 SYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVH 242
            YLLEK+RV++Q+ GERN+H FY LL G E ++  E +L   P  Y++ +Q       V 
Sbjct: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS-TPENYHYLNQSG----CVE 296

Query: 243 SALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAV 302
               SD++S + V  AM V+ FS EEV  V R+LA ILHLGNIEF+    GG Q     V
Sbjct: 297 DKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITA--GGAQ-----V 349

Query: 303 AEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQR 362
           + +  +   AEL       +  +L  R++   G E++       +A  +RD+ A A+Y  
Sbjct: 350 SFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTP-LNVQQAVDSRDSLAMALYAC 408

Query: 363 LFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQL 422
            FEWV+ +INS +  +G +  +      IG+LDI+GFE F VN FEQF INY NEKLQ+ 
Sbjct: 409 CFEWVIKKINSRI--KGNEDFKS-----IGILDIFGFENFEVNHFEQFNINYANEKLQEY 461

Query: 423 FIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRI 482
           F + I   EQ EY REG+ W+ +++ +N   +DL+E+   G+LA+++E  S     TD  
Sbjct: 462 FNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEK-KLGLLALINEE-SHFPQATDST 519

Query: 483 FLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQD 542
            L+ L   H ++  Y   ++           +F +KHYAG+V Y V G ++KNRD    D
Sbjct: 520 LLEKLHSQHANNHFYVKPRVAV--------NNFGVKHYAGEVQYDVRGILEKNRDTFRDD 571

Query: 543 FKRLLYNSTDPTLRAMWPD----GQQDITEV---TKRPLTAGTLFKNSMVALVENLASKE 595
              LL  S    +  ++        QD  +     +RP T  + FK+S+ +L+  L+S  
Sbjct: 572 LLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRP-TVSSQFKDSLHSLMATLSSSN 630

Query: 596 PFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTC 655
           PF+VRCIKPN  K+  + D+    +Q+ Y G+LE VR+R+AG+A R+P+  F  RYK+  
Sbjct: 631 PFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLM 690

Query: 656 EYTWPNHLLGSD-KAAVSALLEQH-GLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPII 713
                N  L  D +   ++LL+ +     +   G +K+F+R       LE+ R   +   
Sbjct: 691 R----NLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLE-QKLEKRREEEVSHA 745

Query: 714 VLLLQKAWRGTLARWRCRR-LRAIYTIMRWFRRHKVRAHLAELQR 757
            ++++    G LAR + R+ L  +  I + +R   +R     L++
Sbjct: 746 AMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKK 790


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score =  426 bits (1095), Expect = e-119
 Identities = 287/814 (35%), Positives = 425/814 (52%), Gaps = 73/814 (8%)

Query: 1   MEDEEGPEY-------------------GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTY 41
           +ED+EG E+                   G  D + L  +     + NL +R+++ +IYTY
Sbjct: 38  VEDDEGKEHWIRAEDFGVLSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTY 97

Query: 42  IGEVLVSVNPYQELPLYGPEAIARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVIS 101
            G +LV+VNP+Q LPLY  E +  Y  R + E PPH++A+AN  Y +MK   RD C +IS
Sbjct: 98  TGSILVAVNPFQVLPLYTLEQVQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIIS 157

Query: 102 GESGAGKTEASKHIMQYIAAVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSR 161
           GESGAGKTE +K I+Q++A ++   Q + +E+    +L++  +LEAFGNA+T RN NSSR
Sbjct: 158 GESGAGKTETTKLILQFLATIS--GQHSWIEQ---QVLEANPILEAFGNAKTIRNDNSSR 212

Query: 162 FGKYMDINFDFKGDPIGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRG--SEDKQLHEL 219
           FGKY+DI F+  G   G  I  +LLEKSRV +Q   ERN+H FY +L G  +EDKQL  L
Sbjct: 213 FGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSL 272

Query: 220 HLERNPAVYNFTHQGAGLNMTVHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAI 279
                P+ Y++   G   N T    L +D + +  +  AM+++ FS  E   V ++LAAI
Sbjct: 273 ---GTPSEYHYLTMG---NCTSCEGL-NDAKDYAHIRSAMKILQFSDSESWDVIKLLAAI 325

Query: 280 LHLGNIEFVETEEGGLQKEGLAVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELI 339
           LHLGN+ F+ +    L  +   V E      V +L       +   L+  T+   G E +
Sbjct: 326 LHLGNVGFMASVFENL--DASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRG-EFV 382

Query: 340 EKGHTAAEASYARDACAKAVYQRLFEWVVNRIN-SVMEPRGRDPRRDGKDTVIGVLDIYG 398
            +    A+A+  RDA  K +Y  LF W+V +IN ++  P  +DP+   +   IG+LDI+G
Sbjct: 383 TRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQDPKNVRR--AIGLLDIFG 440

Query: 399 FEVFPVNSFEQFCINYCNEKLQQLFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVE 458
           FE F  NSFEQ CIN+ NE LQQ F+Q +   EQEEY  E I+W  + Y +N   +DL+ 
Sbjct: 441 FENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISWDYIHYTDNRPTLDLLA 500

Query: 459 RPHRGILAVLDEACSSAGTITDRIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIK 518
                I+++LDE  S     TD   LQ L+  H ++  +         K +   R F I 
Sbjct: 501 LKPMSIISLLDEE-SRFPQGTDLTMLQKLNSVHANNKAFLQ------PKNIHDAR-FGIA 552

Query: 519 HYAGDVTYSVEGFIDKNRDFLFQDFKRLLYNSTDPTLRAMW-------PDGQQDITEV-- 569
           H+AG+V Y  EGF++KNRD L  D   L+Y+S +  LR ++         G   I +   
Sbjct: 553 HFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKA 612

Query: 570 ----------TKRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCR 619
                      KRP T G+ FK S+  L++ L + +P+++RCIKPNE K     D   C 
Sbjct: 613 GNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCL 672

Query: 620 HQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQH- 678
            Q+ Y G++E V +R++GF  R  +  F  R+ +         L G  +     + +   
Sbjct: 673 RQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWL 732

Query: 679 GLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKAWRGTLARWR-CRRLRAIY 737
               D   G +K+F+R  +  + LE  R++++    L +QK  RG   R    R+ RA  
Sbjct: 733 RTDKDWKAGKTKIFLRDHQDTL-LEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAV 791

Query: 738 TIMRWFR----RHKVRAHLAELQRRFQAARQPPL 767
           T+  W+R    R   +  L   +R    AR  PL
Sbjct: 792 TLQAWWRGYCNRRNFKLILVGFERLQAIARSQPL 825


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
           sapiens]
          Length = 1972

 Score =  419 bits (1076), Expect = e-117
 Identities = 266/766 (34%), Positives = 409/766 (53%), Gaps = 51/766 (6%)

Query: 7   PEYGK-PDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAR 65
           P++ K  D   L  +     + NL+ R+  G IYTY G   V VNPY+ LP+Y  + +  
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDM 141

Query: 66  YQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNP 125
           Y+G++ +E PPH+YA+A+ AY++M     D  I+ +GESGAGKTE +K ++QY+A V + 
Sbjct: 142 YKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201

Query: 126 SQRAE----VERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHI 181
            +  +       ++  LL++  +LEAFGNA+T +N NSSRFGK++ INFD  G  +G +I
Sbjct: 202 HKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261

Query: 182 HSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTV 241
            +YLLEKSR ++Q   ER FH FY ++ G+++K   +L LE      N+T    G    V
Sbjct: 262 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE---GFNNYTFLSNGF---V 315

Query: 242 HSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLA 301
                 D++  Q   EAM ++GFS EE  S+ ++++++L LGNI F +        +  +
Sbjct: 316 PIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER----NTDQAS 371

Query: 302 VAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQ 361
           + +      V  L         RS+L   +   GR++++K  T  +A +A +A AKA Y+
Sbjct: 372 MPDNTAAQKVCHLMGINVTDFTRSILTPRI-KVGRDVVQKAQTKEQADFAVEALAKATYE 430

Query: 362 RLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQ 421
           RLF W++ R+N  ++   R        + +G+LDI GFE+F VNSFEQ CINY NEKLQQ
Sbjct: 431 RLFRWILTRVNKALDKTHRQGA-----SFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQ 485

Query: 422 LFIQLILKQEQEEYEREGITWQSVEY-FNNATIVDLVERPHR--GILAVLDEACSSAGTI 478
           LF   +   EQEEY+REGI W  +++  +    ++L+ERP+   G+LA+LDE C      
Sbjct: 486 LFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KA 544

Query: 479 TDRIFLQTLDMHHRHHLHYTS-RQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRD 537
           TD+ F++ L      H  +   +QL   DKT     +F I HYAG V Y+   ++ KN D
Sbjct: 545 TDKSFVEKLCTEQGSHPKFQKPKQL--KDKT-----EFSIIHYAGKVDYNASAWLTKNMD 597

Query: 538 FLFQDFKRLLYNSTDPTLRAMWPD-----GQQDITEVTKRPL------------TAGTLF 580
            L  +   LL  S+D  +  +W D     G   + ++T+  L            T G L+
Sbjct: 598 PLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLY 657

Query: 581 KNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFAS 640
           K  +  L+  L +  P +VRCI PN +K +GKLD      Q+   G+LE +R+ R GF +
Sbjct: 658 KEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPN 717

Query: 641 RQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLV 700
           R  +  F  RY++      P   +   +A +  +            G SK+F R+   L 
Sbjct: 718 RIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLA 776

Query: 701 TLEQSRARLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRH 746
            LE+ R   I  +++  Q   RG LAR    + +   T M+  +R+
Sbjct: 777 HLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRN 822


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
           sapiens]
          Length = 1938

 Score =  419 bits (1076), Expect = e-117
 Identities = 266/766 (34%), Positives = 409/766 (53%), Gaps = 51/766 (6%)

Query: 7   PEYGK-PDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAR 65
           P++ K  D   L  +     + NL+ R+  G IYTY G   V VNPY+ LP+Y  + +  
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDM 141

Query: 66  YQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNP 125
           Y+G++ +E PPH+YA+A+ AY++M     D  I+ +GESGAGKTE +K ++QY+A V + 
Sbjct: 142 YKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201

Query: 126 SQRAE----VERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHI 181
            +  +       ++  LL++  +LEAFGNA+T +N NSSRFGK++ INFD  G  +G +I
Sbjct: 202 HKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261

Query: 182 HSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTV 241
            +YLLEKSR ++Q   ER FH FY ++ G+++K   +L LE      N+T    G    V
Sbjct: 262 ETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE---GFNNYTFLSNGF---V 315

Query: 242 HSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLA 301
                 D++  Q   EAM ++GFS EE  S+ ++++++L LGNI F +        +  +
Sbjct: 316 PIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER----NTDQAS 371

Query: 302 VAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQ 361
           + +      V  L         RS+L   +   GR++++K  T  +A +A +A AKA Y+
Sbjct: 372 MPDNTAAQKVCHLMGINVTDFTRSILTPRI-KVGRDVVQKAQTKEQADFAVEALAKATYE 430

Query: 362 RLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQ 421
           RLF W++ R+N  ++   R        + +G+LDI GFE+F VNSFEQ CINY NEKLQQ
Sbjct: 431 RLFRWILTRVNKALDKTHRQGA-----SFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQ 485

Query: 422 LFIQLILKQEQEEYEREGITWQSVEY-FNNATIVDLVERPHR--GILAVLDEACSSAGTI 478
           LF   +   EQEEY+REGI W  +++  +    ++L+ERP+   G+LA+LDE C      
Sbjct: 486 LFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KA 544

Query: 479 TDRIFLQTLDMHHRHHLHYTS-RQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRD 537
           TD+ F++ L      H  +   +QL   DKT     +F I HYAG V Y+   ++ KN D
Sbjct: 545 TDKSFVEKLCTEQGSHPKFQKPKQL--KDKT-----EFSIIHYAGKVDYNASAWLTKNMD 597

Query: 538 FLFQDFKRLLYNSTDPTLRAMWPD-----GQQDITEVTKRPL------------TAGTLF 580
            L  +   LL  S+D  +  +W D     G   + ++T+  L            T G L+
Sbjct: 598 PLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLY 657

Query: 581 KNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFAS 640
           K  +  L+  L +  P +VRCI PN +K +GKLD      Q+   G+LE +R+ R GF +
Sbjct: 658 KEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPN 717

Query: 641 RQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLV 700
           R  +  F  RY++      P   +   +A +  +            G SK+F R+   L 
Sbjct: 718 RIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLA 776

Query: 701 TLEQSRARLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRH 746
            LE+ R   I  +++  Q   RG LAR    + +   T M+  +R+
Sbjct: 777 HLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRN 822


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score =  418 bits (1075), Expect = e-116
 Identities = 268/748 (35%), Positives = 404/748 (54%), Gaps = 53/748 (7%)

Query: 7   PEYGK-PDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAR 65
           P++ K  D   L  +     + NL+ R+  G IYTY G   V +NPY+ LP+Y    I  
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEM 141

Query: 66  YQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNP 125
           Y+G++ +E PPH+YA++ +AY+ M     D  I+ +GESGAGKTE +K ++QY+A V + 
Sbjct: 142 YRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS 201

Query: 126 SQRAEVERV----KDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHI 181
            +  +   +    +  LL++  +LE+FGNA+T +N NSSRFGK++ INFD  G  +G +I
Sbjct: 202 HKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANI 261

Query: 182 HSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTV 241
            +YLLEKSR ++Q   ER FH FYQLL G+ +      HL+ +  +  F +     N  +
Sbjct: 262 ETYLLEKSRAVRQAKDERTFHIFYQLLSGAGE------HLKSDLLLEGFNNYRFLSNGYI 315

Query: 242 HSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLA 301
                 D+ + Q   EAM ++GFS EE+ S+ ++++++L  GNI F +        +  +
Sbjct: 316 PIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKER----NTDQAS 371

Query: 302 VAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQ 361
           + E  +   +  L         R++L   +   GR+ ++K  T  +A +A +A AKA Y+
Sbjct: 372 MPENTVAQKLCHLLGMNVMEFTRAILTPRI-KVGRDYVQKAQTKEQADFAVEALAKATYE 430

Query: 362 RLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQ 421
           RLF W+V+RIN  ++      +R G  + IG+LDI GFE+F +NSFEQ CINY NEKLQQ
Sbjct: 431 RLFRWLVHRINKALD----RTKRQGA-SFIGILDIAGFEIFELNSFEQLCINYTNEKLQQ 485

Query: 422 LFIQLILKQEQEEYEREGITWQSVEY-FNNATIVDLVERPHR--GILAVLDEACSSAGTI 478
           LF   +   EQEEY+REGI W  +++  +    +DL+ERP    G+LA+LDE C      
Sbjct: 486 LFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFP-KA 544

Query: 479 TDRIFLQTLDMHHRHHLHYTS-RQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRD 537
           TD+ F++ L      H  +   RQL   DK      DF I HYAG V Y  + ++ KN D
Sbjct: 545 TDKTFVEKLVQEQGSHSKFQKPRQL--KDKA-----DFCIIHYAGKVDYKADEWLMKNMD 597

Query: 538 FLFQDFKRLLYNSTDPTLRAMWPD-----GQQDITEVTKRPL------------TAGTLF 580
            L  +   LL+ S+D  +  +W D     G   +T +T+               T G L+
Sbjct: 598 PLNDNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLY 657

Query: 581 KNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFAS 640
           K S+  L+  L +  P +VRCI PN +K AGKLD +    Q+   G+LE +R+ R GF +
Sbjct: 658 KESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPN 717

Query: 641 RQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDV-AFGHSKLFIRSPRTL 699
           R  +  F  RY++      P   +   K A   ++    L  ++   G SK+F R+   L
Sbjct: 718 RIVFQEFRQRYEILTPNAIPKGFM-DGKQACERMIRALELDPNLYRIGQSKIFFRA-GVL 775

Query: 700 VTLEQSRARLIPIIVLLLQKAWRGTLAR 727
             LE+ R   I  I++  Q   RG LAR
Sbjct: 776 AHLEEERDLKITDIIIFFQAVCRGYLAR 803


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  418 bits (1075), Expect = e-116
 Identities = 279/786 (35%), Positives = 421/786 (53%), Gaps = 70/786 (8%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGR-IYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           G+ D   L  +     + NL++RF   + IYTY G VLV++NPY++LP+YG + I  Y G
Sbjct: 70  GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
           + + +  PH++AVA  AYK M    R+  I++SGESGAGKT ++K+ M+Y A V+  +  
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
           A VE   + +L S  ++E+ GNA+T RN NSSRFGKY++I FD +   IG ++ +YLLEK
Sbjct: 190 ANVE---EKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV+ Q   ERN+H FYQL   ++  +   L L  N   +N+T QG   +  +    D+ 
Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGG--SPVIEGVDDAK 303

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGL----QKEGLAVAE 304
           E +H    +A  ++G S      + RILA ILHLGN+ F   +        + E L +  
Sbjct: 304 EMAH--TRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCI-- 359

Query: 305 EALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLF 364
                   +L     + +   L  R +A+     I K  +  +A+ ARDA AK +Y +LF
Sbjct: 360 ------FCDLMGVDYEEMCHWLCHRKLATATETYI-KPISKLQATNARDALAKHIYAKLF 412

Query: 365 EWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFI 424
            W+V+ +N  +    +      + + IGVLDIYGFE F +NSFEQFCINY NEKLQQ F 
Sbjct: 413 NWIVDNVNQALHSAVK------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFN 466

Query: 425 QLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFL 484
             + K EQEEY +E I W  +++++N   ++L+E    GIL +LDE C      TD  + 
Sbjct: 467 MHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIE-SKLGILDLLDEECKMPKG-TDDTWA 524

Query: 485 QTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFK 544
           Q L   +  HL+    +    +K     + F I+H+A  V Y  EGF++KN+D +F++  
Sbjct: 525 QKL---YNTHLN----KCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQI 577

Query: 545 RLLYNSTDPTLRAMWPDGQQDI----------TEVTKRPL----------------TAGT 578
           ++L +S    L  ++ D ++ I          T +T+ P                 T G 
Sbjct: 578 KVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGH 637

Query: 579 LFKNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGF 638
            F+NS+  L+E L +  P YVRCIKPN+ K     DE     Q+   G+LE +R+  AGF
Sbjct: 638 QFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGF 697

Query: 639 ASRQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPR 697
            SR  Y  F  RY++  +      +L   K     +LE+  L  D   FG +K+F R+ +
Sbjct: 698 PSRWTYQEFFSRYRVLMK---QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQ 754

Query: 698 TLVTLEQSRARLIPIIVLLLQKAWRGTLARWRCRRLR-AIYTIMRWFRRHKVRAHLAELQ 756
            +  LE+ RA  +    + +QK  RG L R +  R+R A  T+ R+ R ++ R + A+  
Sbjct: 755 -VAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY-AKFL 812

Query: 757 RRFQAA 762
           RR +AA
Sbjct: 813 RRTKAA 818


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  418 bits (1075), Expect = e-116
 Identities = 279/786 (35%), Positives = 421/786 (53%), Gaps = 70/786 (8%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGR-IYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           G+ D   L  +     + NL++RF   + IYTY G VLV++NPY++LP+YG + I  Y G
Sbjct: 70  GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
           + + +  PH++AVA  AYK M    R+  I++SGESGAGKT ++K+ M+Y A V+  +  
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
           A VE   + +L S  ++E+ GNA+T RN NSSRFGKY++I FD +   IG ++ +YLLEK
Sbjct: 190 ANVE---EKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV+ Q   ERN+H FYQL   ++  +   L L  N   +N+T QG   +  +    D+ 
Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGG--SPVIEGVDDAK 303

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGL----QKEGLAVAE 304
           E +H    +A  ++G S      + RILA ILHLGN+ F   +        + E L +  
Sbjct: 304 EMAH--TRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCI-- 359

Query: 305 EALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLF 364
                   +L     + +   L  R +A+     I K  +  +A+ ARDA AK +Y +LF
Sbjct: 360 ------FCDLMGVDYEEMCHWLCHRKLATATETYI-KPISKLQATNARDALAKHIYAKLF 412

Query: 365 EWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFI 424
            W+V+ +N  +    +      + + IGVLDIYGFE F +NSFEQFCINY NEKLQQ F 
Sbjct: 413 NWIVDNVNQALHSAVK------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFN 466

Query: 425 QLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFL 484
             + K EQEEY +E I W  +++++N   ++L+E    GIL +LDE C      TD  + 
Sbjct: 467 MHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIE-SKLGILDLLDEECKMPKG-TDDTWA 524

Query: 485 QTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFK 544
           Q L   +  HL+    +    +K     + F I+H+A  V Y  EGF++KN+D +F++  
Sbjct: 525 QKL---YNTHLN----KCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQI 577

Query: 545 RLLYNSTDPTLRAMWPDGQQDI----------TEVTKRPL----------------TAGT 578
           ++L +S    L  ++ D ++ I          T +T+ P                 T G 
Sbjct: 578 KVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGH 637

Query: 579 LFKNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGF 638
            F+NS+  L+E L +  P YVRCIKPN+ K     DE     Q+   G+LE +R+  AGF
Sbjct: 638 QFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGF 697

Query: 639 ASRQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPR 697
            SR  Y  F  RY++  +      +L   K     +LE+  L  D   FG +K+F R+ +
Sbjct: 698 PSRWTYQEFFSRYRVLMK---QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQ 754

Query: 698 TLVTLEQSRARLIPIIVLLLQKAWRGTLARWRCRRLR-AIYTIMRWFRRHKVRAHLAELQ 756
            +  LE+ RA  +    + +QK  RG L R +  R+R A  T+ R+ R ++ R + A+  
Sbjct: 755 -VAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY-AKFL 812

Query: 757 RRFQAA 762
           RR +AA
Sbjct: 813 RRTKAA 818


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
           sapiens]
          Length = 1979

 Score =  416 bits (1068), Expect = e-116
 Identities = 266/773 (34%), Positives = 409/773 (52%), Gaps = 58/773 (7%)

Query: 7   PEYGK-PDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAR 65
           P++ K  D   L  +     + NL+ R+  G IYTY G   V VNPY+ LP+Y  + +  
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDM 141

Query: 66  YQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNP 125
           Y+G++ +E PPH+YA+A+ AY++M     D  I+ +GESGAGKTE +K ++QY+A V + 
Sbjct: 142 YKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201

Query: 126 SQRAE-----------VERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKG 174
            +  +              ++  LL++  +LEAFGNA+T +N NSSRFGK++ INFD  G
Sbjct: 202 HKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG 261

Query: 175 DPIGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQG 234
             +G +I +YLLEKSR ++Q   ER FH FY ++ G+++K   +L LE      N+T   
Sbjct: 262 YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE---GFNNYTFLS 318

Query: 235 AGLNMTVHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGG 294
            G    V      D++  Q   EAM ++GFS EE  S+ ++++++L LGNI F +     
Sbjct: 319 NGF---VPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER--- 372

Query: 295 LQKEGLAVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDA 354
              +  ++ +      V  L         RS+L   +   GR++++K  T  +A +A +A
Sbjct: 373 -NTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRI-KVGRDVVQKAQTKEQADFAVEA 430

Query: 355 CAKAVYQRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINY 414
            AKA Y+RLF W++ R+N  ++   R        + +G+LDI GFE+F VNSFEQ CINY
Sbjct: 431 LAKATYERLFRWILTRVNKALDKTHRQGA-----SFLGILDIAGFEIFEVNSFEQLCINY 485

Query: 415 CNEKLQQLFIQLILKQEQEEYEREGITWQSVEY-FNNATIVDLVERPHR--GILAVLDEA 471
            NEKLQQLF   +   EQEEY+REGI W  +++  +    ++L+ERP+   G+LA+LDE 
Sbjct: 486 TNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEE 545

Query: 472 CSSAGTITDRIFLQTLDMHHRHHLHYTS-RQLCPTDKTMEFGRDFRIKHYAGDVTYSVEG 530
           C      TD+ F++ L      H  +   +QL   DKT     +F I HYAG V Y+   
Sbjct: 546 CWFP-KATDKSFVEKLCTEQGSHPKFQKPKQL--KDKT-----EFSIIHYAGKVDYNASA 597

Query: 531 FIDKNRDFLFQDFKRLLYNSTDPTLRAMWPD-----GQQDITEVTKRPL----------- 574
           ++ KN D L  +   LL  S+D  +  +W D     G   + ++T+  L           
Sbjct: 598 WLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMF 657

Query: 575 -TAGTLFKNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRV 633
            T G L+K  +  L+  L +  P +VRCI PN +K +GKLD      Q+   G+LE +R+
Sbjct: 658 RTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRI 717

Query: 634 RRAGFASRQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFI 693
            R GF +R  +  F  RY++      P   +   +A +  +            G SK+F 
Sbjct: 718 CRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFF 777

Query: 694 RSPRTLVTLEQSRARLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRH 746
           R+   L  LE+ R   I  +++  Q   RG LAR    + +   T M+  +R+
Sbjct: 778 RT-GVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRN 829


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
           sapiens]
          Length = 1945

 Score =  416 bits (1068), Expect = e-116
 Identities = 266/773 (34%), Positives = 409/773 (52%), Gaps = 58/773 (7%)

Query: 7   PEYGK-PDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAR 65
           P++ K  D   L  +     + NL+ R+  G IYTY G   V VNPY+ LP+Y  + +  
Sbjct: 82  PKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDM 141

Query: 66  YQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNP 125
           Y+G++ +E PPH+YA+A+ AY++M     D  I+ +GESGAGKTE +K ++QY+A V + 
Sbjct: 142 YKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASS 201

Query: 126 SQRAE-----------VERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKG 174
            +  +              ++  LL++  +LEAFGNA+T +N NSSRFGK++ INFD  G
Sbjct: 202 HKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTG 261

Query: 175 DPIGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQG 234
             +G +I +YLLEKSR ++Q   ER FH FY ++ G+++K   +L LE      N+T   
Sbjct: 262 YIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE---GFNNYTFLS 318

Query: 235 AGLNMTVHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGG 294
            G    V      D++  Q   EAM ++GFS EE  S+ ++++++L LGNI F +     
Sbjct: 319 NGF---VPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER--- 372

Query: 295 LQKEGLAVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDA 354
              +  ++ +      V  L         RS+L   +   GR++++K  T  +A +A +A
Sbjct: 373 -NTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRI-KVGRDVVQKAQTKEQADFAVEA 430

Query: 355 CAKAVYQRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINY 414
            AKA Y+RLF W++ R+N  ++   R        + +G+LDI GFE+F VNSFEQ CINY
Sbjct: 431 LAKATYERLFRWILTRVNKALDKTHRQGA-----SFLGILDIAGFEIFEVNSFEQLCINY 485

Query: 415 CNEKLQQLFIQLILKQEQEEYEREGITWQSVEY-FNNATIVDLVERPHR--GILAVLDEA 471
            NEKLQQLF   +   EQEEY+REGI W  +++  +    ++L+ERP+   G+LA+LDE 
Sbjct: 486 TNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEE 545

Query: 472 CSSAGTITDRIFLQTLDMHHRHHLHYTS-RQLCPTDKTMEFGRDFRIKHYAGDVTYSVEG 530
           C      TD+ F++ L      H  +   +QL   DKT     +F I HYAG V Y+   
Sbjct: 546 CWFP-KATDKSFVEKLCTEQGSHPKFQKPKQL--KDKT-----EFSIIHYAGKVDYNASA 597

Query: 531 FIDKNRDFLFQDFKRLLYNSTDPTLRAMWPD-----GQQDITEVTKRPL----------- 574
           ++ KN D L  +   LL  S+D  +  +W D     G   + ++T+  L           
Sbjct: 598 WLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMF 657

Query: 575 -TAGTLFKNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRV 633
            T G L+K  +  L+  L +  P +VRCI PN +K +GKLD      Q+   G+LE +R+
Sbjct: 658 RTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRI 717

Query: 634 RRAGFASRQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFI 693
            R GF +R  +  F  RY++      P   +   +A +  +            G SK+F 
Sbjct: 718 CRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFF 777

Query: 694 RSPRTLVTLEQSRARLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRH 746
           R+   L  LE+ R   I  +++  Q   RG LAR    + +   T M+  +R+
Sbjct: 778 RT-GVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRN 829


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score =  413 bits (1062), Expect = e-115
 Identities = 268/765 (35%), Positives = 404/765 (52%), Gaps = 52/765 (6%)

Query: 7   PEYGK-PDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAR 65
           P++ K  D   L  +     + NL+ R+  G IYTY G   V +NPY+ LP+Y  E +  
Sbjct: 78  PKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEM 137

Query: 66  YQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVT-- 123
           Y+G++ +E PPH+YA+ + AY++M     D  I+ +GESGAGKTE +K ++QY+A V   
Sbjct: 138 YKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASS 197

Query: 124 --NPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHI 181
             +   + E+ER    LL++  +LEAFGNA+T +N NSSRFGK++ INFD  G  +G +I
Sbjct: 198 HKSKKDQGELER---QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANI 254

Query: 182 HSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTV 241
            +YLLEKSR ++Q   ER FH FY LL G+ +    +L LE     Y F   G   ++T+
Sbjct: 255 ETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNK-YRFLSNG---HVTI 310

Query: 242 HSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLA 301
               D D    Q   EAMR++G   EE   + R+++ +L LGNI F +        +  +
Sbjct: 311 PGQQDKD--MFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKER----NTDQAS 364

Query: 302 VAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQ 361
           + +      V+ L         R +L   +   GR+ ++K  T  +A +A +A AKA Y+
Sbjct: 365 MPDNTAAQKVSHLLGINVTDFTRGILTPRI-KVGRDYVQKAQTKEQADFAIEALAKATYE 423

Query: 362 RLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQ 421
           R+F W+V RIN  ++      +R G  + IG+LDI GFE+F +NSFEQ CINY NEKLQQ
Sbjct: 424 RMFRWLVLRINKALD----KTKRQGA-SFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQ 478

Query: 422 LFIQLILKQEQEEYEREGITWQSVEY-FNNATIVDLVERP--HRGILAVLDEACSSAGTI 478
           LF   +   EQEEY+REGI W  +++  +    +DL+E+P    GILA+LDE C      
Sbjct: 479 LFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFP-KA 537

Query: 479 TDRIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDF 538
           TD+ F++ +      H  +         K ++   DF I HYAG V Y  + ++ KN D 
Sbjct: 538 TDKSFVEKVMQEQGTHPKFQK------PKQLKDKADFCIIHYAGKVDYKADEWLMKNMDP 591

Query: 539 LFQDFKRLLYNSTDPTLRAMWPD-----GQQDITEVTKRPL------------TAGTLFK 581
           L  +   LL+ S+D  +  +W D     G   +  +++  L            T G L+K
Sbjct: 592 LNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYK 651

Query: 582 NSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASR 641
             +  L+  L +  P +VRCI PN +K AGKLD +    Q+   G+LE +R+ R GF +R
Sbjct: 652 EQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNR 711

Query: 642 QPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVT 701
             +  F  RY++    + P   +   +A V  +            G SK+F R+   L  
Sbjct: 712 VVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRA-GVLAH 770

Query: 702 LEQSRARLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRH 746
           LE+ R   I  +++  Q   RG LAR    + +   T M+  +R+
Sbjct: 771 LEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRN 815


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score =  409 bits (1050), Expect = e-114
 Identities = 268/767 (34%), Positives = 409/767 (53%), Gaps = 56/767 (7%)

Query: 7   PEYGKP-DFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAR 65
           P++ K  D   L  +     + NL+ R+  G IYTY G   V +NPY++LP+Y    +  
Sbjct: 102 PKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEM 161

Query: 66  YQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTN- 124
           Y+G++ +E PPH+YAV   AY++M     D  I+ +GESGAGKTE +K ++QY+A V + 
Sbjct: 162 YRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS 221

Query: 125 ------PSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIG 178
                 P    E+ER    LL++  +LEAFGNA+T +N NSSRFGK++ INFD  G  +G
Sbjct: 222 PKGRKEPGVPGELER---QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 278

Query: 179 GHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLN 238
            +I +YLLEKSR ++Q   E +FH FYQLL G+ ++   +L LE   + Y F   G    
Sbjct: 279 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE-PCSHYRFLTNGPS-- 335

Query: 239 MTVHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKE 298
               S+   + +  Q   E++RV+GFS EE+ S+ R+++A+L  GNI            +
Sbjct: 336 ----SSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRER----NTD 387

Query: 299 GLAVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKA 358
              + +      +  L         R+LL   +   GR+ ++K  T  +A +A +A AKA
Sbjct: 388 QATMPDNTAAQKLCRLLGLGVTDFSRALLTPRI-KVGRDYVQKAQTKEQADFALEALAKA 446

Query: 359 VYQRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEK 418
            Y+RLF W+V R+N  ++   R PR+    + +G+LDI GFE+F +NSFEQ CINY NEK
Sbjct: 447 TYERLFRWLVLRLNRALD---RSPRQGA--SFLGILDIAGFEIFQLNSFEQLCINYTNEK 501

Query: 419 LQQLFIQLILKQEQEEYEREGITWQSVEY-FNNATIVDLVERPHR--GILAVLDEACSSA 475
           LQQLF   +   EQEEY+REGI W  +++  +    +DL+ERP    G+LA+LDE C   
Sbjct: 502 LQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFP 561

Query: 476 GTITDRIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKN 535
              TD+ F++ +      H  +         + +    DF + HYAG V Y    ++ KN
Sbjct: 562 -KATDKSFVEKVAQEQGGHPKF------QRPRHLRDQADFSVLHYAGKVDYKANEWLMKN 614

Query: 536 RDFLFQDFKRLLYNSTDPTLRAMWPD-----GQQDITEVTKRP----------LTAGTLF 580
            D L  +   LL+ STD     +W D     G + ++ +   P           T G L+
Sbjct: 615 MDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLY 674

Query: 581 KNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFAS 640
           K S+  L+  L++  P +VRCI PN +K AGKL+      Q+   G+LE +R+ R GF +
Sbjct: 675 KESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPN 734

Query: 641 RQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDV-AFGHSKLFIRSPRTL 699
           R  +  F  RY++      P   +   K A   +++   L  ++   G SK+F R+   L
Sbjct: 735 RILFQEFRQRYEILTPNAIPKGFM-DGKQACEKMIQALELDPNLYRVGQSKIFFRA-GVL 792

Query: 700 VTLEQSRARLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRH 746
             LE+ R   +  I++  Q A RG LAR   ++ +   + +R  +R+
Sbjct: 793 AQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRN 839


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  406 bits (1044), Expect = e-113
 Identities = 270/761 (35%), Positives = 403/761 (52%), Gaps = 63/761 (8%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRFEKGR-IYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           G+ D   L  +     + NL++RF + + IYTY G +LV++NPY++LP+YG   I  Y G
Sbjct: 68  GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
           + + +  PH++AVA  AYK M   +R+  I++SGESGAGKT ++++ M+Y A V+     
Sbjct: 128 QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
           A VE   D +L S  + EA GNA+T RN NSSRFGKY +I+FD +   IG ++ +YLLEK
Sbjct: 188 AHVE---DKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEK 244

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV+ Q   ERN+H FYQL   ++  +   L L  +   +N+T  G   N  +    D  
Sbjct: 245 SRVVFQSENERNYHIFYQLCASAQQSEFKHLKL-GSAEEFNYTRMGG--NTVIEGVNDRA 301

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
           E      T    ++GF  +    V +ILAAILHLGN++       G ++  ++  +++ +
Sbjct: 302 EMVETQKT--FTLLGFKEDFQMDVFKILAAILHLGNVQITAV---GNERSSVS-EDDSHL 355

Query: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368
               EL       V + L  R + +   E + K  T  +A  ARDA AK +Y  LF+++V
Sbjct: 356 KVFCELLGLESGRVAQWLCNRKIVTSS-ETVVKPMTRPQAVNARDALAKKIYAHLFDFIV 414

Query: 369 NRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLIL 428
            RIN  ++  G+      + T IGVLDIYGFE F VNSFEQFCINY NEKLQQ F   + 
Sbjct: 415 ERINQALQFSGK------QHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVF 468

Query: 429 KQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTLD 488
           K EQEEY +E I W  +++++N  ++DL+E    GIL +LDE C      TD  +LQ L 
Sbjct: 469 KLEQEEYMKEDIPWTLIDFYDNQPVIDLIE-AKMGILELLDEECLLPHG-TDENWLQKL- 525

Query: 489 MHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL- 547
                + ++ +R     +K       F I+H+A  V Y  EGF++KNRD ++     +L 
Sbjct: 526 -----YNNFVNRNPL-FEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILR 579

Query: 548 ------------YNSTDPTLRAMWPDGQQDITEVTKRPL---------TAGTLFKNSMVA 586
                        N T P+     P G     +  K+ +         T G+ F++S+  
Sbjct: 580 ASKFHLCANFFQENPTPPS-----PFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYL 634

Query: 587 LVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSR 646
           L+E L +  P YVRCIKPN++K+  + D      Q+   G+LE +R+    + SR  Y  
Sbjct: 635 LMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIE 694

Query: 647 FLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQ--GDVAFGHSKLFIRSPRTLVTLEQ 704
           F  RY +         L  SDK  V  ++    +Q      FG +K+F R+ + +  LE+
Sbjct: 695 FYSRYGILMT---KQELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQ-VAYLEK 750

Query: 705 SRARLIPIIVLLLQKAWRGTLARWR-CRRLRAIYTIMRWFR 744
            R   +    +++QK  RG L R +  R  RA   I ++FR
Sbjct: 751 LRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFR 791


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score =  405 bits (1042), Expect = e-113
 Identities = 268/772 (34%), Positives = 409/772 (52%), Gaps = 58/772 (7%)

Query: 7   PEYGKP-DFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAR 65
           P++ K  D   L  +     + NL+ R+  G IYTY G   V +NPY++LP+Y    +  
Sbjct: 102 PKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEM 161

Query: 66  YQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTN- 124
           Y+G++ +E PPH+YAV   AY++M     D  I+ +GESGAGKTE +K ++QY+A V + 
Sbjct: 162 YRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS 221

Query: 125 ------PSQRAEVERV-----KDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFK 173
                 P   A V  V     +  LL++  +LEAFGNA+T +N NSSRFGK++ INFD  
Sbjct: 222 PKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVA 281

Query: 174 GDPIGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQ 233
           G  +G +I +YLLEKSR ++Q   E +FH FYQLL G+ ++   +L LE   + Y F   
Sbjct: 282 GYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE-PCSHYRFLTN 340

Query: 234 GAGLNMTVHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEG 293
           G        S+   + +  Q   E++RV+GFS EE+ S+ R+++A+L  GNI        
Sbjct: 341 GPS------SSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRER-- 392

Query: 294 GLQKEGLAVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARD 353
               +   + +      +  L         R+LL   +   GR+ ++K  T  +A +A +
Sbjct: 393 --NTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRI-KVGRDYVQKAQTKEQADFALE 449

Query: 354 ACAKAVYQRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCIN 413
           A AKA Y+RLF W+V R+N  ++   R PR+    + +G+LDI GFE+F +NSFEQ CIN
Sbjct: 450 ALAKATYERLFRWLVLRLNRALD---RSPRQGA--SFLGILDIAGFEIFQLNSFEQLCIN 504

Query: 414 YCNEKLQQLFIQLILKQEQEEYEREGITWQSVEY-FNNATIVDLVERPHR--GILAVLDE 470
           Y NEKLQQLF   +   EQEEY+REGI W  +++  +    +DL+ERP    G+LA+LDE
Sbjct: 505 YTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDE 564

Query: 471 ACSSAGTITDRIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEG 530
            C      TD+ F++ +      H  +         + +    DF + HYAG V Y    
Sbjct: 565 ECWFP-KATDKSFVEKVAQEQGGHPKF------QRPRHLRDQADFSVLHYAGKVDYKANE 617

Query: 531 FIDKNRDFLFQDFKRLLYNSTDPTLRAMWPD-----GQQDITEVTKRP----------LT 575
           ++ KN D L  +   LL+ STD     +W D     G + ++ +   P           T
Sbjct: 618 WLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRT 677

Query: 576 AGTLFKNSMVALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRR 635
            G L+K S+  L+  L++  P +VRCI PN +K AGKL+      Q+   G+LE +R+ R
Sbjct: 678 VGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICR 737

Query: 636 AGFASRQPYSRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQGDV-AFGHSKLFIR 694
            GF +R  +  F  RY++      P   +   K A   +++   L  ++   G SK+F R
Sbjct: 738 QGFPNRILFQEFRQRYEILTPNAIPKGFM-DGKQACEKMIQALELDPNLYRVGQSKIFFR 796

Query: 695 SPRTLVTLEQSRARLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRH 746
           +   L  LE+ R   +  I++  Q A RG LAR   ++ +   + +R  +R+
Sbjct: 797 A-GVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRN 847


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  405 bits (1040), Expect = e-112
 Identities = 265/781 (33%), Positives = 411/781 (52%), Gaps = 62/781 (7%)

Query: 10  GKPDFVLLDQVTMEDFMRNLQLRF-EKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68
           G+ D   L  +     + NL++RF E   IYTY G VLV++NPY++LP+YG + I  Y G
Sbjct: 70  GENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSG 129

Query: 69  RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128
           + + +  PH++AVA  AYK M    ++  I++SGESGAGKT ++K+ M+Y A V   +  
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASE 189

Query: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188
             +E   + +L S+ ++EA GNA+T RN NSSRFGKY+ I FD +   IG ++ +YLLEK
Sbjct: 190 TNIE---EKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEK 246

Query: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248
           SRV+ Q   ERN+H FYQL   +   +  EL L  +   + +T QG   ++      +  
Sbjct: 247 SRVVFQADDERNYHIFYQLCAAAGLPEFKELAL-TSAEDFFYTSQGGDTSIEGVDDAEDF 305

Query: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVA-EEAL 307
           E++ QA T    ++G       S+ +I+A+ILHLG++      +G    +  +++ ++  
Sbjct: 306 EKTRQAFT----LLGVKESHQMSIFKIIASILHLGSVAIQAERDG----DSCSISPQDVY 357

Query: 308 VDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWV 367
           + +   L       +   L  R + +   E   K  +  +   AR+A AK +Y +LF W+
Sbjct: 358 LSNFCRLLGVEHSQMEHWLCHRKLVTTS-ETYVKTMSLQQVINARNALAKHIYAQLFGWI 416

Query: 368 VNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLI 427
           V  IN  +    +      + + IGVLDIYGFE F VNSFEQFCINY NEKLQQ F   +
Sbjct: 417 VEHINKALHTSLK------QHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470

Query: 428 LKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTL 487
            K EQEEY +E I W  +++++N   +DL+E    GIL +LDE C      TD+ + Q L
Sbjct: 471 FKLEQEEYMKEQIPWTLIDFYDNQPCIDLIE-AKLGILDLLDEEC-KVPKGTDQNWAQKL 528

Query: 488 DMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL 547
              H    H+   ++  T         F I H+A  V Y  +GF++KNRD ++++   +L
Sbjct: 529 YDRHSSSQHFQKPRMSNT--------AFIIVHFADKVEYLSDGFLEKNRDTVYEEQINIL 580

Query: 548 YNSTDPTLRAMWPDGQQDITEVT-----------------------KRPLTAGTLFKNSM 584
             S  P +  ++ D +  +   T                       +   T G  F+ S+
Sbjct: 581 KASKFPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSL 640

Query: 585 VALVENLASKEPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPY 644
             L+E L +  P YVRCIKPN++K+    D      Q+   G+LE +R+  AG+ SR  Y
Sbjct: 641 HLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAY 700

Query: 645 SRFLLRYKMTCEYTWPNHLLGSDKAAVSALLEQHGLQ--GDVAFGHSKLFIRSPRTLVTL 702
             F  RY++  +      L  +DK A+   + ++ ++      FG +K+F R+ + +  L
Sbjct: 701 HDFFNRYRVLVK---KRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQ-VAYL 756

Query: 703 EQSRARLIPIIVLLLQKAWRGTLARWRCRRLR-AIYTIMRWFRRHKVRAHLAELQRRFQA 761
           E+ RA       +++QK  RG L + +  RL+ A  T+ R+ R H  R  LAE  RR +A
Sbjct: 757 EKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLAR-RLAEHLRRIRA 815

Query: 762 A 762
           A
Sbjct: 816 A 816


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,917,982
Number of Sequences: 37866
Number of extensions: 1725675
Number of successful extensions: 4281
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3829
Number of HSP's gapped (non-prelim): 119
length of query: 1018
length of database: 18,247,518
effective HSP length: 112
effective length of query: 906
effective length of database: 14,006,526
effective search space: 12689912556
effective search space used: 12689912556
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.