Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 23957702
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
(811 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 1692 0.0
gi|11415040 matriptase [Homo sapiens] 407 e-113
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 395 e-110
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 277 2e-74
gi|117956391 protease, serine, 33 [Homo sapiens] 222 9e-58
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 218 1e-56
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 216 7e-56
gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 215 1e-55
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 215 1e-55
gi|58218970 protease, serine, 36 [Homo sapiens] 215 2e-55
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 211 3e-54
gi|11545839 protease, serine, 22 [Homo sapiens] 209 6e-54
gi|13994276 marapsin [Homo sapiens] 208 1e-53
gi|4506153 prostasin preproprotein [Homo sapiens] 203 6e-52
gi|223942069 enterokinase precursor [Homo sapiens] 202 1e-51
gi|21614531 testisin isoform 2 [Homo sapiens] 197 4e-50
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 197 4e-50
gi|33695155 hepsin [Homo sapiens] 196 6e-50
gi|4504481 hepsin [Homo sapiens] 196 6e-50
gi|5803197 testisin isoform 1 [Homo sapiens] 195 2e-49
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 194 2e-49
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 194 3e-49
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 194 3e-49
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 194 4e-49
gi|4503627 coagulation factor XI precursor [Homo sapiens] 192 8e-49
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ... 191 2e-48
gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo ... 191 2e-48
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 191 3e-48
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 189 7e-48
gi|29244926 corin [Homo sapiens] 186 6e-47
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 1692 bits (4382), Expect = 0.0
Identities = 811/811 (100%), Positives = 811/811 (100%)
Query: 1 MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLL 60
MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLL
Sbjct: 1 MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLL 60
Query: 61 ALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQK 120
ALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQK
Sbjct: 61 ALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQK 120
Query: 121 MLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELL 180
MLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELL
Sbjct: 121 MLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELL 180
Query: 181 STVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDH 240
STVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDH
Sbjct: 181 STVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDH 240
Query: 241 LASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVE 300
LASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVE
Sbjct: 241 LASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVE 300
Query: 301 VLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYY 360
VLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYY
Sbjct: 301 VLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYY 360
Query: 361 SPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAE 420
SPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAE
Sbjct: 361 SPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAE 420
Query: 421 RIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDC 480
RIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDC
Sbjct: 421 RIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDC 480
Query: 481 PNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCED 540
PNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCED
Sbjct: 481 PNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCED 540
Query: 541 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRH 600
RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRH
Sbjct: 541 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRH 600
Query: 601 ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYH 660
ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYH
Sbjct: 601 ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYH 660
Query: 661 EEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNAL 720
EEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNAL
Sbjct: 661 EEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNAL 720
Query: 721 QKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGL 780
QKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGL
Sbjct: 721 QKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGL 780
Query: 781 VSWGLGCGRPNYFGVYTRITGVISWIQQVVT 811
VSWGLGCGRPNYFGVYTRITGVISWIQQVVT
Sbjct: 781 VSWGLGCGRPNYFGVYTRITGVISWIQQVVT 811
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 407 bits (1046), Expect = e-113
Identities = 260/811 (32%), Positives = 389/811 (47%), Gaps = 89/811 (10%)
Query: 62 LLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKM 121
LLVL G L+W+ L Y+ +V V +V++G +R+ N +F S+ F S +K +
Sbjct: 66 LLVLLGIGFLVWH-LQYR-DVRVQKVFNGYMRITNENFVDAYENSNSTEFVSLASKVKDA 123
Query: 122 LKELITSTR-LGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELL 180
LK L + LG Y+ S+V +F EG + ++W IP+H E + ++ EE +
Sbjct: 124 LKLLYSGVPFLGPYHKESAVTAFSEGSVIAYYWSEFSIPQHL-----VEEAERVMAEERV 178
Query: 181 STVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDH 240
+ A R+ +V K + C + +++R P
Sbjct: 179 VMLPPRA----RSLKSFVVTSVVAFPTDSKTVQRTQDN-SCSFGLHARGVELMRFTTPGF 233
Query: 241 LASS------CLWHLQGPKDLMLKLRLE-WTLAECRDR----LAMYDVAGPLEKRLITSV 289
S C W L+G D +L L + LA C +R + +Y+ P+E + +
Sbjct: 234 PDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHALVQL 293
Query: 290 YGCSRQEPVVEVLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQG 349
G + +S ++ + + F + FQ ++ +QG
Sbjct: 294 CGTYPPSYNLTFHSSQNVLLITLITNTERRHPGF----EATFFQLPRMSSCGGRLRKAQG 349
Query: 350 VLSTPYFPSYYSPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRL 409
++PY+P +Y P C+W++ VP+ + + Y L C + I +
Sbjct: 350 TFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEINGEKY 409
Query: 410 CGLRILQPYAERIPVVATAG---ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSV 466
CG ER V T+ IT+ F S S T G Y Y+ SDPCPG+F C
Sbjct: 410 CG--------ERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRT 461
Query: 467 ------------------------------------NGLCVP---ACDGVKDCPNGLDER 487
N C P CD V DC + DE+
Sbjct: 462 GRCIRKELRCDGWADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQ 521
Query: 488 NCVCRA-TFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEG--VPCGTFTFQCEDRSCV 544
C C A TF+C + C+S + C+G+ DC +GSDE C + V C T++C + C+
Sbjct: 522 GCSCPAQTFRCS-NGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCL 580
Query: 545 KKPNPQCDGRPDCRDGSDEEHCDCGLQG--PSSRIVGGAVSSEGEWPWQASLQVRGR-HI 601
K NP+CDG+ DC DGSDE+ CDCGL+ +R+VGG + EGEWPWQ SL G+ HI
Sbjct: 581 SKGNPECDGKEDCSDGSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHI 640
Query: 602 CGGALIADRWVITAAHCFQEDS---MASTVLWTVFLGKVWQNSRW-PGEVSFKVSRLLLH 657
CG +LI+ W+++AAHC+ +D + WT FLG Q+ R PG ++ R++ H
Sbjct: 641 CGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISH 700
Query: 658 PYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPIS 717
P+ + + DYD+ALL+L+ P S+ VRP+CLP SH F G W+TGWG + GG +
Sbjct: 701 PFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGA 760
Query: 718 NALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFL 777
LQK ++++I Q C + Q+TPRM+C G+ G D+CQGDSGGPL GR F
Sbjct: 761 LILQKGEIRVINQTTCENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQ 820
Query: 778 AGLVSWGLGCGRPNYFGVYTRITGVISWIQQ 808
AG+VSWG GC + N GVYTR+ WI++
Sbjct: 821 AGVVSWGDGCAQRNKPGVYTRLPLFRDWIKE 851
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 395 bits (1016), Expect = e-110
Identities = 240/745 (32%), Positives = 368/745 (49%), Gaps = 61/745 (8%)
Query: 93 RVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITSTRLGTYYNSSSV--YSFGEGPLTC 150
R+ N F + ++ES F S + Q+++ + T++ +Y S V S +G L
Sbjct: 3 RITNIEFLPEYRQKESREFLSVSRTVQQVINLVYTTSAFSKFYEQSVVADVSNNKGGLLV 62
Query: 151 FFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAVPYRAEYEVDPEGLVILEASVK 210
FW + +P + + + V A+L + + +++ + +V VD + +V+ +
Sbjct: 63 HFWIVFVMPRAKGHIFCEDCVAAILKDSIQTSIINRTSVGSLQGLAVDMDSVVLNDK--- 119
Query: 211 DIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASS-----CLWHLQGPKDLMLKLRLEWTL 265
GC +Y Y + L L P ++++ C + L +++L ++
Sbjct: 120 ---------GCSQYFYA---EHLSLHYPLEISAASGRLMCHFKLVAIVGYLIRLSIKSIQ 167
Query: 266 AEC----RDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMAVVWKK------- 314
E D L +YD P+ ++ + C ++ +++ +M V +K
Sbjct: 168 IEADNCVTDSLTIYDSLLPIRSSILYRI--CEPTRTLMSFVSTNNLMLVTFKSPHIRRLS 225
Query: 315 GLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWHLTVPS 374
G+ +Y++ + Q CE + + + +G +S+PY+PSYY P+ C+W
Sbjct: 226 GIRAYFEV-------IPEQKCENTVLVKDITGFEGKISSPYYPSYYPPKCKCTWKFQTSL 278
Query: 375 LDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAGITINF 434
G+AL F Y++ ++ C G W I CG + R+P + + I
Sbjct: 279 STLGIALKFYNYSITKKSMK-GCEHGWWEINEHMYCGSYMDHQTIFRVP---SPLVHIQL 334
Query: 435 TSQISLTGPGVRVHYGLYNQSDPCP-GEFLCSVNGLCVPA---CDGVKDCPNGLDERNCV 490
L+ + YG YN S PCP G F CS +GLCVP CDGV DC + DE CV
Sbjct: 335 QCSSRLSDKPLLAEYGSYNISQPCPVGSFRCS-SGLCVPQAQRCDGVNDCFDESDELFCV 393
Query: 491 CRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQ 550
C S P +CDG DC NG DE+ C + +PC TF+C + C +K N +
Sbjct: 394 SPQP-ACNTSSFRQHGPLICDGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAK 452
Query: 551 CDGRPDCRDGSDEEHCDCGLQGPS-SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD 609
CDG DC DGSDEE C C + RI+GG + EG WPWQ SL G CG ++I+
Sbjct: 453 CDGTVDCPDGSDEEGCTCSRSSSALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISR 512
Query: 610 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV 669
W+++AAHCF + ++ WT LG Q + + V R+++H Y+ + DYD+
Sbjct: 513 EWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGN---AKFVSPVRRIVVHEYYNSQTFDYDI 569
Query: 670 ALLQLD--HPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREG-GPISNALQKVDVQ 726
ALLQL P ++P+C+P G CW+TGWG E S LQ+ +V+
Sbjct: 570 ALLQLSIAWPETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVE 629
Query: 727 LIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALS-GRWFLAGLVSWGL 785
LI Q LC Y +T RMLCAG GK+DAC+GDSGGPL C+ S G+W L G+VSWG
Sbjct: 630 LIDQTLCVSTYGI-ITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGH 688
Query: 786 GCGRPNYFGVYTRITGVISWIQQVV 810
G GRPN+ GVYTR++ + WI + V
Sbjct: 689 GSGRPNFPGVYTRVSNFVPWIHKYV 713
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 277 bits (709), Expect = 2e-74
Identities = 131/285 (45%), Positives = 179/285 (62%), Gaps = 6/285 (2%)
Query: 531 CGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGP---SSRIVGGAVSSEGE 587
C +F C + CV K NP+CD + DC DGSDE HC+CGLQ + RIVGG +S GE
Sbjct: 154 CPGNSFSCGNSQCVTKVNPECDDQEDCSDGSDEAHCECGLQPAWRMAGRIVGGMEASPGE 213
Query: 588 WPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEV 647
+PWQASL+ H CG A+I RW+++AAHCF E W ++G + + V
Sbjct: 214 FPWQASLRENKEHFCGAAIINARWLVSAAHCFNE--FQDPTKWVAYVGATYLSGSEASTV 271
Query: 648 SFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGW 707
+V +++ HP + D+ D+DVA+L+L P+ ++PVCLPA +H F P C I+GW
Sbjct: 272 RAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGW 331
Query: 708 GALREGGPIS-NALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPL 766
G L+E + LQK V+L+ Q LC+ +Y + +T RM+CAGY GK D+CQGDSGGPL
Sbjct: 332 GYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGKVDSCQGDSGGPL 391
Query: 767 VCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT 811
VC+ SGR+FLAG+VSWG+GC GVY R+T + WI + T
Sbjct: 392 VCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATT 436
Score = 238 bits (606), Expect = 2e-62
Identities = 117/244 (47%), Positives = 158/244 (64%), Gaps = 6/244 (2%)
Query: 567 DCGLQGPS-SRIVGGAVSSEGEWPWQASLQVRGR-HICGGALIADRWVITAAHCFQEDSM 624
DCGL + +RIVGG+ + GEWPWQ SL +R R H CG L+A+RW+++AAHCF D
Sbjct: 816 DCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCF--DVY 873
Query: 625 ASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAV 684
W FLG + + G++ +V+R+ HP++ + DYDVALL+L PV RS V
Sbjct: 874 GDPKQWAAFLGTPFLSGA-EGQLE-RVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLV 931
Query: 685 RPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTPR 744
RP+CLP + G C ITGWG++REGG ++ LQK V+L+ + C Y Q++ R
Sbjct: 932 RPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSR 991
Query: 745 MLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVIS 804
MLCAG+ +G D+C GD+GGPL C+ SGRW L G+ SWG GCGRP++ GVYTR+ V
Sbjct: 992 MLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRG 1051
Query: 805 WIQQ 808
WI Q
Sbjct: 1052 WIGQ 1055
Score = 201 bits (511), Expect = 2e-51
Identities = 97/238 (40%), Positives = 141/238 (59%), Gaps = 4/238 (1%)
Query: 575 SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFL 634
+R+VGG ++ GE PWQ SL+ RH CG ++ DRW+++AAHCF + L
Sbjct: 502 TRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQV---RAHL 558
Query: 635 GKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSH 694
G V + R++LHP + D+D+A+L+L P+ + ++PVCLP
Sbjct: 559 GTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQ 618
Query: 695 FFEPGLHCWITGWGALREGGPIS-NALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKG 753
F G C I+GWG +EG LQK V +I Q CS +Y + +T RM+CAG+ +G
Sbjct: 619 KFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEG 678
Query: 754 KKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT 811
K D+CQGDSGGPL C+ G ++LAG+VSWG+GC + GVYTRIT + WI ++++
Sbjct: 679 KVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMS 736
Score = 37.0 bits (84), Expect = 0.073
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
Query: 454 QSDPCPGEFLCSVNGLCV----PACDGVKDCPNGLDERNCVC 491
+S CPG N CV P CD +DC +G DE +C C
Sbjct: 150 KSGRCPGNSFSCGNSQCVTKVNPECDDQEDCSDGSDEAHCEC 191
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 222 bits (566), Expect = 9e-58
Identities = 124/255 (48%), Positives = 149/255 (58%), Gaps = 14/255 (5%)
Query: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627
CG SSRIVGG +GEWPWQAS+Q RG H+CGG+LIA +WV+TAAHCF ++ +
Sbjct: 28 CGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAE 87
Query: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPV 687
+ V LG + S P +S V R+LL P + ED D+ALLQL PV SA V+PV
Sbjct: 88 --YRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPV 145
Query: 688 CLPARSHFFEPGLHCWITGWGALREGGPIS--NALQKVDVQLIPQDLCSEVYRYQ----- 740
CLP PG C +TGWG+LR G P+ LQ V V L+ C +Y
Sbjct: 146 CLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQ 205
Query: 741 ----VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVY 796
V P LCAGY +G KDACQGDSGGPL C SG W L G+VSWG GC PN GVY
Sbjct: 206 AERIVLPGSLCAGYPQGHKDACQGDSGGPLTC-LQSGSWVLVGVVSWGKGCALPNRPGVY 264
Query: 797 TRITGVISWIQQVVT 811
T + WIQ V+
Sbjct: 265 TSVATYSPWIQARVS 279
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 218 bits (556), Expect = 1e-56
Identities = 115/306 (37%), Positives = 172/306 (56%), Gaps = 24/306 (7%)
Query: 522 EEQCQEGVPCGTFTFQ-----CEDRSCVKKPNPQCDGRP-------DCRDGSDEEHCDCG 569
+E C + + C FT+ C++ C DG P G C+ G
Sbjct: 319 QETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTG 378
Query: 570 LQG-----PSSRIVGGAVSSEGEWPWQASLQVR---GRHICGGALIADRWVITAAHCFQE 621
S+RIVGG SS GEWPWQ SLQV+ RH+CGG+LI +WV+TAAHCF
Sbjct: 379 DNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-- 436
Query: 622 DSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRS 681
D + +W ++ G + + ++ +++H ++ ++D+AL++L P+ +
Sbjct: 437 DGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYT 496
Query: 682 AAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYR-YQ 740
+P+CLP++ +CW+TGWG +E G I N LQKV++ L+ + C + Y+ Y+
Sbjct: 497 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK 556
Query: 741 VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRIT 800
+T RM+CAGY++G KDAC+GDSGGPLVCK +G W L G+ SWG GC R GVYT++
Sbjct: 557 ITQRMVCAGYKEGGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVA 615
Query: 801 GVISWI 806
+ WI
Sbjct: 616 EYMDWI 621
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 216 bits (550), Expect = 7e-56
Identities = 110/243 (45%), Positives = 143/243 (58%), Gaps = 5/243 (2%)
Query: 567 DCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAS 626
+CG + +SRIVGG + G WPWQAS+ + RH CGG+++A RWV+TAAHC +A
Sbjct: 208 ECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLAR 267
Query: 627 TVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRP 686
W V G V ++ P + + V R++ HP + +HDYDVALL+L + S V
Sbjct: 268 LSSWRVHAGLVSHSAVRPHQGAL-VERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGA 326
Query: 687 VCLPARSHFFEPGLHCWITGWGALREGGPI-SNALQKVDVQLIPQDLCSE--VYRYQVTP 743
VCLPA+ F G CW++GWG S+ LQ V L LC+ VY +TP
Sbjct: 327 VCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTP 386
Query: 744 RMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVI 803
RMLCAGY G+ DACQGDSGGPLVC W L G+VSWG GC PN+ GVY ++ +
Sbjct: 387 RMLCAGYLDGRADACQGDSGGPLVCPD-GDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFL 445
Query: 804 SWI 806
WI
Sbjct: 446 DWI 448
>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
Length = 423
Score = 215 bits (548), Expect = 1e-55
Identities = 114/249 (45%), Positives = 149/249 (59%), Gaps = 14/249 (5%)
Query: 565 HCDCGLQ-----GPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCF 619
HC CG + G S RIVGG EGEWPWQASLQ G H CG LI W+++AAHCF
Sbjct: 176 HC-CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCF 234
Query: 620 QEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVV 679
+ + WT G + P ++ + R+++H ++ SHDYD++L +L PV
Sbjct: 235 T--TYKNPARWTASFGVTIK----PSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVP 288
Query: 680 RSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRY 739
+ AV VCLP S+ F+PG ++TG+GAL+ G N L++ V LI C+E Y
Sbjct: 289 YTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY 348
Query: 740 Q--VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYT 797
+TPRMLCAG +GK DACQGDSGGPLV W+LAG+VSWG C +PN GVYT
Sbjct: 349 NDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYT 408
Query: 798 RITGVISWI 806
R+T + WI
Sbjct: 409 RVTALRDWI 417
>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
Length = 423
Score = 215 bits (548), Expect = 1e-55
Identities = 114/249 (45%), Positives = 149/249 (59%), Gaps = 14/249 (5%)
Query: 565 HCDCGLQ-----GPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCF 619
HC CG + G S RIVGG EGEWPWQASLQ G H CG LI W+++AAHCF
Sbjct: 176 HC-CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCF 234
Query: 620 QEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVV 679
+ + WT G + P ++ + R+++H ++ SHDYD++L +L PV
Sbjct: 235 T--TYKNPARWTASFGVTIK----PSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVP 288
Query: 680 RSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRY 739
+ AV VCLP S+ F+PG ++TG+GAL+ G N L++ V LI C+E Y
Sbjct: 289 YTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY 348
Query: 740 Q--VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYT 797
+TPRMLCAG +GK DACQGDSGGPLV W+LAG+VSWG C +PN GVYT
Sbjct: 349 NDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYT 408
Query: 798 RITGVISWI 806
R+T + WI
Sbjct: 409 RVTALRDWI 417
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 215 bits (547), Expect = 2e-55
Identities = 112/260 (43%), Positives = 155/260 (59%), Gaps = 12/260 (4%)
Query: 562 DEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQE 621
+ E DCG PS+RIVGG+ + G WPWQ SL G HICGG+LIA WV++AAHCF
Sbjct: 32 EPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMT 91
Query: 622 D-SMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVR 680
+ ++ W+V LG Q+ G + V+ +++ + + D+ALL+L P
Sbjct: 92 NGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASL 151
Query: 681 SAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISN--ALQKVDVQLIPQDLCSEVY- 737
AV PVCLP SH F G CW TGWG ++E P+ LQ+V+++L+ + C +Y
Sbjct: 152 GPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYS 211
Query: 738 -------RYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRP 790
Q+ P MLCAGY +G++D CQGDSGGPLVC+ GRWF AG+ S+G GCGR
Sbjct: 212 QPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFGFGCGRR 270
Query: 791 NYFGVYTRITGVISWIQQVV 810
N GV+T + +WI++ V
Sbjct: 271 NRPGVFTAVATYEAWIREQV 290
Score = 113 bits (283), Expect = 6e-25
Identities = 77/223 (34%), Positives = 108/223 (48%), Gaps = 17/223 (7%)
Query: 580 GAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQ 639
G G WPW+A + V G C GAL+++ WV+ A CF + + + + + +V
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLL 385
Query: 640 NSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPG 699
SR E +V+RL+ H D+ D+ALLQL PV SAA RPVCLP H+F PG
Sbjct: 386 PSRPRAE---RVARLVQHENASWDNAS-DLALLQLRTPVNLSAASRPVCLPHPEHYFLPG 441
Query: 700 LHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVT--------PRMLCAGYR 751
C + WG G P ++ +L+ C +Y Q P LC Y+
Sbjct: 442 SRCRLARWG---RGEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQ 498
Query: 752 -KGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYF 793
K + +C DS L+C+ G WFLAG+ + GC RP F
Sbjct: 499 EKEEVGSCWNDSRWSLLCQE-EGTWFLAGIRDFPSGCLRPRAF 540
Score = 105 bits (262), Expect = 2e-22
Identities = 70/225 (31%), Positives = 109/225 (48%), Gaps = 24/225 (10%)
Query: 564 EHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDS 623
EH CGL+ ++ + G + WPW A + V G +C G L+A WV+ A HC
Sbjct: 584 EHGACGLRLEAAPV--GVL-----WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPG 636
Query: 624 MASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH---PYHEEDSHDYDVALLQLDHPVVR 680
+ V+LG+ +S G +VSRL++ P H +ALL+L V
Sbjct: 637 STTVPYIEVYLGRAGASSLPQGH---QVSRLVISIRLPQHL--GLRPPLALLELSSRVEP 691
Query: 681 SAAVRPVCL-PARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRY 739
S + P+CL PA PG CW+ GW ++ P++ A V ++ Q +C +Y+
Sbjct: 692 SPSALPICLHPAG---IPPGASCWVLGWKEPQDRVPVAAA-----VSILTQRICDCLYQG 743
Query: 740 QVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWG 784
+ P LC Y +G+++ C+ S PL+C+ G W L G+ G
Sbjct: 744 ILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQG 788
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 211 bits (536), Expect = 3e-54
Identities = 107/242 (44%), Positives = 149/242 (61%), Gaps = 7/242 (2%)
Query: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627
CGL+ + RIVGGA++S+ +WPWQ SL HICGG LI +WV+TAAHCF
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376
Query: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPV 687
W V+ G N E + ++ ++++ + ++ DYD+AL++L P+ SA + P
Sbjct: 377 EGWKVYAGT--SNLHQLPEAA-SIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433
Query: 688 CLPARSHFFEPGLHCWITGWGALRE-GGPISNALQKVDVQLIPQDLCSE--VYRYQVTPR 744
CLP F CWITG+G RE S L++V V LI C++ VY +TPR
Sbjct: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPR 493
Query: 745 MLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVIS 804
M+CAG +G +D+CQGDSGGPLVC+ + RW+LAG+ SWG GCG+ N GVYT++T V+
Sbjct: 494 MMCAGDLRGGRDSCQGDSGGPLVCEQ-NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLP 552
Query: 805 WI 806
WI
Sbjct: 553 WI 554
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 209 bits (533), Expect = 6e-54
Identities = 107/253 (42%), Positives = 156/253 (61%), Gaps = 14/253 (5%)
Query: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627
CG +R+VGG S++ EWPW S+Q G H C G+L+ RWVITAAHCF +D++
Sbjct: 41 CGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCF-KDNLNKP 99
Query: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHP---YHEEDSHDYDVALLQLDHPVVRSAAV 684
L++V LG WQ PG S KV + P Y ++ D+AL++L+ + S V
Sbjct: 100 YLFSVLLG-AWQLGN-PGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERV 157
Query: 685 RPVCLPARSHFFEPGLHCWITGWGALREGGPISN--ALQKVDVQLIPQDLCSEVY----- 737
P+CLP S P HCWI+GWG++++G P+ + LQK+ V +I ++CS +Y
Sbjct: 158 LPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAG 217
Query: 738 RYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYT 797
+ +T MLCAGY +G++DAC GDSGGPL+C+ + G W LAG++SWG GC N GVY
Sbjct: 218 QGPITEDMLCAGYLEGERDACLGDSGGPLMCQ-VDGAWLLAGIISWGEGCAERNRPGVYI 276
Query: 798 RITGVISWIQQVV 810
++ SW++++V
Sbjct: 277 SLSAHRSWVEKIV 289
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 208 bits (530), Expect = 1e-53
Identities = 110/254 (43%), Positives = 153/254 (60%), Gaps = 14/254 (5%)
Query: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627
CG +R+VGG + EGEWPWQ S+Q G H CGG+LIA++WV+TAAHCF+ S T
Sbjct: 26 CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTS--ET 83
Query: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPV 687
L+ V LG P + +V ++ +P ++ + DVAL++L+ PV + + PV
Sbjct: 84 SLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPV 143
Query: 688 CLPARSHFFEPGLHCWITGWGALREGG--PISNALQKVDVQLIPQDLCSEVYR------Y 739
CLP S FE G++CW+TGWG+ E P LQK+ V +I C+ +Y Y
Sbjct: 144 CLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGY 203
Query: 740 Q---VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVY 796
Q + MLCAG+ +GKKDAC+GDSGGPLVC + W AG++SWG GC R N GVY
Sbjct: 204 QPKTIKNDMLCAGFEEGKKDACKGDSGGPLVC-LVGQSWLQAGVISWGEGCARQNRPGVY 262
Query: 797 TRITGVISWIQQVV 810
R+T +WI +++
Sbjct: 263 IRVTAHHNWIHRII 276
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 203 bits (516), Expect = 6e-52
Identities = 104/262 (39%), Positives = 150/262 (57%), Gaps = 14/262 (5%)
Query: 560 GSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCF 619
G++ CG+ P +RI GG+ + G+WPWQ S+ G H+CGG+L++++WV++AAHCF
Sbjct: 29 GAEGAEAPCGV-APQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCF 87
Query: 620 QEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVV 679
+ + V LG +S + ++ HP + ++ D+ALLQL P+
Sbjct: 88 PSEHHKEA--YEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPIT 145
Query: 680 RSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPI--SNALQKVDVQLIPQDLCSEVY 737
S +RP+CLPA + F GLHC +TGWG + + LQ+++V LI ++ C+ +Y
Sbjct: 146 FSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLY 205
Query: 738 RYQVTPR--------MLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGR 789
P M+CAGY +G KDACQGDSGGPL C + G W+L G+VSWG CG
Sbjct: 206 NIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGA 264
Query: 790 PNYFGVYTRITGVISWIQQVVT 811
N GVYT + SWIQ VT
Sbjct: 265 RNRPGVYTLASSYASWIQSKVT 286
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 202 bits (513), Expect = 1e-51
Identities = 133/413 (32%), Positives = 194/413 (46%), Gaps = 47/413 (11%)
Query: 424 VVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPA---CDGVKDC 480
V+A G NFT+ L P +PC + NG CVP CDG C
Sbjct: 621 VLARGGFKANFTTGYHLGIP------------EPCKADHFQCKNGECVPLVNLCDGHLHC 668
Query: 481 PNGLDE------------RNCVCRATFQ------CKEDSTCISLPKVCDGQPDCLNGSDE 522
+G DE N + R Q C E+ T VC Q L +
Sbjct: 669 EDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVC--QLLGLGSGNS 726
Query: 523 EQCQEGVPCGTFTF--QCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCG----LQGPSSR 576
+ G F D + P+ QC D H CG Q + +
Sbjct: 727 SKPIFSTDGGPFVKLNTAPDGHLILTPSQQC--LQDSLIRLQCNHKSCGKKLAAQDITPK 784
Query: 577 IVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLG- 635
IVGG+ + EG WPW L GR +CG +L++ W+++AAHC ++ + WT LG
Sbjct: 785 IVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSK-WTAILGL 843
Query: 636 KVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHF 695
+ N P V + ++++P++ D D+A++ L+ V + ++P+CLP +
Sbjct: 844 HMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQV 903
Query: 696 FEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLC-SEVYRYQVTPRMLCAGYRKGK 754
F PG +C I GWG + G +N LQ+ DV L+ + C ++ Y +T M+CAGY +G
Sbjct: 904 FPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGG 963
Query: 755 KDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQ 807
D+CQGDSGGPL+C+ + RWFLAG+ S+G C PN GVY R++ WIQ
Sbjct: 964 IDSCQGDSGGPLMCQE-NNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQ 1015
Score = 32.0 bits (71), Expect = 2.4
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 4/43 (9%)
Query: 453 NQSDPC-PGEFLCSVNGLCVPA---CDGVKDCPNGLDERNCVC 491
N S C PG C+ C+ A CDG +CP+G DE N +C
Sbjct: 179 NVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMC 221
Score = 32.0 bits (71), Expect = 2.4
Identities = 12/27 (44%), Positives = 17/27 (62%)
Query: 497 CKEDSTCISLPKVCDGQPDCLNGSDEE 523
C + TCI CDG+ +C +GSDE+
Sbjct: 191 CTDALTCIKADLFCDGEVNCPDGSDED 217
Score = 30.0 bits (66), Expect = 9.0
Identities = 14/40 (35%), Positives = 20/40 (50%)
Query: 529 VPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDC 568
+ C + C D K + CDG +C DGSDE++ C
Sbjct: 182 IECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMC 221
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 197 bits (500), Expect = 4e-50
Identities = 104/254 (40%), Positives = 153/254 (60%), Gaps = 14/254 (5%)
Query: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627
CG + +SRIVGG + G WPWQ SL++ H+CG +L++ RW +TAAHCF+ D ++
Sbjct: 33 CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETD-LSDP 91
Query: 628 VLWTVFLGKVW-QNSRWPGEVSFK---VSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAA 683
W V G++ S W + + VS + L P + +S YD+AL++L PV +
Sbjct: 92 SGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNS-PYDIALVKLSAPVTYTKH 150
Query: 684 VRPVCLPARSHFFEPGLHCWITGWGALREGG--PISNALQKVDVQLIPQDLCSEV----- 736
++P+CL A + FE CW+TGWG ++E P + LQ+V V +I +C+ +
Sbjct: 151 IQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYS 210
Query: 737 YRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVY 796
+R + M+CAG +G KDAC GDSGGPL C +G W+ G+VSWG+GCGRPN GVY
Sbjct: 211 FRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNK-NGLWYQIGVVSWGVGCGRPNRPGVY 269
Query: 797 TRITGVISWIQQVV 810
T I+ WIQ+++
Sbjct: 270 TNISHHFEWIQKLM 283
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 197 bits (500), Expect = 4e-50
Identities = 114/293 (38%), Positives = 161/293 (54%), Gaps = 40/293 (13%)
Query: 531 CGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPW 590
CG ++ P C GRP D RIVGG + G WPW
Sbjct: 6 CGLLLLLAVPGVSLRTLQPGC-GRPQVSDAG-------------GRIVGGHAAPAGAWPW 51
Query: 591 QASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFK 650
QASL++R H+CGG+L++ +WV+TAAHCF +S + V LG++ E++
Sbjct: 52 QASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSD--YQVHLGEL--------EITLS 101
Query: 651 -----VSRLLLHPYHE-EDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWI 704
V +++LH + D+AL++L PV S+ + PVCLP S F PG+ CW+
Sbjct: 102 PHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWV 161
Query: 705 TGWGALREGGPI--SNALQKVDVQLIPQDLCSEVYRYQ----VTPRMLCAGYRKGKKDAC 758
TGWG REG P+ +L++V V ++ + C Y + P MLCA +G DAC
Sbjct: 162 TGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDAC 218
Query: 759 QGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT 811
Q DSGGPLVC+ ++G W AG+VSWG GCGRPN GVYTR+ ++WI++ +T
Sbjct: 219 QDDSGGPLVCQ-VNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHIT 270
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 196 bits (499), Expect = 6e-50
Identities = 106/256 (41%), Positives = 148/256 (57%), Gaps = 15/256 (5%)
Query: 567 DCGLQG-PSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMA 625
DCG + P RIVGG +S G WPWQ SL+ G H+CGG+L++ WV+TAAHCF E +
Sbjct: 152 DCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRV 211
Query: 626 STVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH----PYHEEDSHD--YDVALLQLDHPVV 679
+ W VF G V Q S P + V ++ H P+ + +S + D+AL+ L P+
Sbjct: 212 LS-RWRVFAGAVAQAS--PHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLP 268
Query: 680 RSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLC--SEVY 737
+ ++PVCLPA G C +TGWG + G + LQ+ V +I D+C ++ Y
Sbjct: 269 LTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFY 328
Query: 738 RYQVTPRMLCAGYRKGKKDACQGDSGGPLVCK---ALSGRWFLAGLVSWGLGCGRPNYFG 794
Q+ P+M CAGY +G DACQGDSGGP VC+ + + RW L G+VSWG GC G
Sbjct: 329 GNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPG 388
Query: 795 VYTRITGVISWIQQVV 810
VYT+++ WI Q +
Sbjct: 389 VYTKVSDFREWIFQAI 404
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 196 bits (499), Expect = 6e-50
Identities = 106/256 (41%), Positives = 148/256 (57%), Gaps = 15/256 (5%)
Query: 567 DCGLQG-PSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMA 625
DCG + P RIVGG +S G WPWQ SL+ G H+CGG+L++ WV+TAAHCF E +
Sbjct: 152 DCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRV 211
Query: 626 STVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH----PYHEEDSHD--YDVALLQLDHPVV 679
+ W VF G V Q S P + V ++ H P+ + +S + D+AL+ L P+
Sbjct: 212 LS-RWRVFAGAVAQAS--PHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLP 268
Query: 680 RSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLC--SEVY 737
+ ++PVCLPA G C +TGWG + G + LQ+ V +I D+C ++ Y
Sbjct: 269 LTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFY 328
Query: 738 RYQVTPRMLCAGYRKGKKDACQGDSGGPLVCK---ALSGRWFLAGLVSWGLGCGRPNYFG 794
Q+ P+M CAGY +G DACQGDSGGP VC+ + + RW L G+VSWG GC G
Sbjct: 329 GNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPG 388
Query: 795 VYTRITGVISWIQQVV 810
VYT+++ WI Q +
Sbjct: 389 VYTKVSDFREWIFQAI 404
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 195 bits (495), Expect = 2e-49
Identities = 104/255 (40%), Positives = 153/255 (60%), Gaps = 14/255 (5%)
Query: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDS-MAS 626
CG + +SRIVGG + G WPWQ SL++ H+CG +L++ RW +TAAHCF+ S ++
Sbjct: 33 CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92
Query: 627 TVLWTVFLGKVW-QNSRWPGEVSFK---VSRLLLHPYHEEDSHDYDVALLQLDHPVVRSA 682
W V G++ S W + + VS + L P + +S YD+AL++L PV +
Sbjct: 93 PSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNS-PYDIALVKLSAPVTYTK 151
Query: 683 AVRPVCLPARSHFFEPGLHCWITGWGALREGG--PISNALQKVDVQLIPQDLCSEV---- 736
++P+CL A + FE CW+TGWG ++E P + LQ+V V +I +C+ +
Sbjct: 152 HIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 211
Query: 737 -YRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGV 795
+R + M+CAG +G KDAC GDSGGPL C +G W+ G+VSWG+GCGRPN GV
Sbjct: 212 SFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNK-NGLWYQIGVVSWGVGCGRPNRPGV 270
Query: 796 YTRITGVISWIQQVV 810
YT I+ WIQ+++
Sbjct: 271 YTNISHHFEWIQKLM 285
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 194 bits (494), Expect = 2e-49
Identities = 129/383 (33%), Positives = 190/383 (49%), Gaps = 47/383 (12%)
Query: 462 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVC---------------RATFQCKEDSTC 503
FLC +P CDG DCP G DE +CV R+T Q + +T
Sbjct: 62 FLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATG 121
Query: 504 ISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQC------EDRSCVKKPNPQCDGRP-- 555
D + L E C++ TF+ +D V+ + R
Sbjct: 122 NWFSACFDNFTEALA---ETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRN 178
Query: 556 ---DCRDGSDEE-HC-DCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADR 610
C GS HC CG + R+VGG +S WPWQ S+Q +H+CGG+++
Sbjct: 179 SSGPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPH 238
Query: 611 WVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEV-SFKVSRLLLHPYHEEDSHDYDV 669
WV+TAAHCF++ + VF KV S G S V+++++ ++ D D+
Sbjct: 239 WVLTAAHCFRKHT-------DVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDI 291
Query: 670 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALRE-GGPISNALQKVDVQLI 728
AL++L P+ S VRP+CLP P WI GWG ++ GG +S+ L + VQ+I
Sbjct: 292 ALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVI 351
Query: 729 PQDLCS--EVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLG 786
C+ + Y+ +VT +M+CAG +G D CQGDSGGPL+ + S +W + G+VSWG G
Sbjct: 352 DSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQ--SDQWHVVGIVSWGYG 409
Query: 787 CGRPNYFGVYTRITGVISWIQQV 809
CG P+ GVYT+++ ++WI V
Sbjct: 410 CGGPSTPGVYTKVSAYLNWIYNV 432
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 194 bits (493), Expect = 3e-49
Identities = 125/371 (33%), Positives = 171/371 (46%), Gaps = 65/371 (17%)
Query: 496 QCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCD--- 552
+C TCI+ CDG C G DE +C + F Q S K +P C
Sbjct: 156 ECDSSGTCINPSNWCDGVSHCPGGEDENRCVR-LYGPNFILQVYS-SQRKSWHPVCQDDW 213
Query: 553 ----GRPDCRD-----------------GSDE-----------------EHCD------- 567
GR CRD GS H D
Sbjct: 214 NENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAV 273
Query: 568 -------CGLQGPSSR---IVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAH 617
CG+ SSR IVGG + G WPWQ SL V+ H+CGG++I W++TAAH
Sbjct: 274 VSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAH 333
Query: 618 CFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHP 677
C E + + WT F G + Q+ + G ++V +++ HP ++ + + D+AL++L P
Sbjct: 334 CV-EKPLNNPWHWTAFAGILRQSFMFYG-AGYQVEKVISHPNYDSKTKNNDIALMKLQKP 391
Query: 678 VVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVY 737
+ + V+PVCLP +P CWI+GWGA E G S L V LI C+ Y
Sbjct: 392 LTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRY 451
Query: 738 RYQ--VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGV 795
Y +TP M+CAG+ +G D+CQGDSGGPLV + + W+L G SWG GC + GV
Sbjct: 452 VYDNLITPAMICAGFLQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGV 510
Query: 796 YTRITGVISWI 806
Y + WI
Sbjct: 511 YGNVMVFTDWI 521
Score = 33.5 bits (75), Expect = 0.81
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 3/30 (10%)
Query: 464 CSVNGLCVPA---CDGVKDCPNGLDERNCV 490
C +G C+ CDGV CP G DE CV
Sbjct: 157 CDSSGTCINPSNWCDGVSHCPGGEDENRCV 186
Score = 31.2 bits (69), Expect = 4.0
Identities = 15/47 (31%), Positives = 19/47 (40%), Gaps = 1/47 (2%)
Query: 528 GVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPS 574
G C +C+ P+ CDG C G DE C L GP+
Sbjct: 147 GSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRC-VRLYGPN 192
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 194 bits (493), Expect = 3e-49
Identities = 125/371 (33%), Positives = 171/371 (46%), Gaps = 65/371 (17%)
Query: 496 QCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCD--- 552
+C TCI+ CDG C G DE +C + F Q S K +P C
Sbjct: 119 ECDSSGTCINPSNWCDGVSHCPGGEDENRCVR-LYGPNFILQVYS-SQRKSWHPVCQDDW 176
Query: 553 ----GRPDCRD-----------------GSDE-----------------EHCD------- 567
GR CRD GS H D
Sbjct: 177 NENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAV 236
Query: 568 -------CGLQGPSSR---IVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAH 617
CG+ SSR IVGG + G WPWQ SL V+ H+CGG++I W++TAAH
Sbjct: 237 VSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAH 296
Query: 618 CFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHP 677
C E + + WT F G + Q+ + G ++V +++ HP ++ + + D+AL++L P
Sbjct: 297 CV-EKPLNNPWHWTAFAGILRQSFMFYG-AGYQVEKVISHPNYDSKTKNNDIALMKLQKP 354
Query: 678 VVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVY 737
+ + V+PVCLP +P CWI+GWGA E G S L V LI C+ Y
Sbjct: 355 LTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRY 414
Query: 738 RYQ--VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGV 795
Y +TP M+CAG+ +G D+CQGDSGGPLV + + W+L G SWG GC + GV
Sbjct: 415 VYDNLITPAMICAGFLQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGV 473
Query: 796 YTRITGVISWI 806
Y + WI
Sbjct: 474 YGNVMVFTDWI 484
Score = 33.5 bits (75), Expect = 0.81
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 3/30 (10%)
Query: 464 CSVNGLCVPA---CDGVKDCPNGLDERNCV 490
C +G C+ CDGV CP G DE CV
Sbjct: 120 CDSSGTCINPSNWCDGVSHCPGGEDENRCV 149
Score = 31.2 bits (69), Expect = 4.0
Identities = 15/47 (31%), Positives = 19/47 (40%), Gaps = 1/47 (2%)
Query: 528 GVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPS 574
G C +C+ P+ CDG C G DE C L GP+
Sbjct: 110 GSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRC-VRLYGPN 155
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 194 bits (492), Expect = 4e-49
Identities = 128/378 (33%), Positives = 188/378 (49%), Gaps = 42/378 (11%)
Query: 462 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVC---------------RATFQCKEDSTC 503
FLC +P CDG DCP G DE +CV R+T Q + +T
Sbjct: 62 FLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATG 121
Query: 504 ISLPKVCDGQPDCLNGSDEEQCQE-GVPCGTFTFQCEDRSCVKKPNPQCDGRP-----DC 557
D + L E C++ G +D V+ + R C
Sbjct: 122 NWFSACFDNFTEALA---ETACRQMGYSRAVEIGPDQDLDVVEITENSQELRMRNSSGPC 178
Query: 558 RDGSDEE-HC-DCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITA 615
GS HC CG + R+VGG +S WPWQ S+Q +H+CGG+++ WV+TA
Sbjct: 179 LSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTA 238
Query: 616 AHCFQEDSMASTVLWTVFLGKVWQNSRWPGEV-SFKVSRLLLHPYHEEDSHDYDVALLQL 674
AHCF++ + VF KV S G S V+++++ ++ D D+AL++L
Sbjct: 239 AHCFRKHT-------DVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKL 291
Query: 675 DHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALRE-GGPISNALQKVDVQLIPQDLC 733
P+ S VRP+CLP P WI GWG ++ GG +S+ L + VQ+I C
Sbjct: 292 QFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRC 351
Query: 734 S--EVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPN 791
+ + Y+ +VT +M+CAG +G D CQGDSGGPL+ + S +W + G+VSWG GCG P+
Sbjct: 352 NADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQ--SDQWHVVGIVSWGYGCGGPS 409
Query: 792 YFGVYTRITGVISWIQQV 809
GVYT+++ ++WI V
Sbjct: 410 TPGVYTKVSAYLNWIYNV 427
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 192 bits (489), Expect = 8e-49
Identities = 95/235 (40%), Positives = 139/235 (59%), Gaps = 7/235 (2%)
Query: 576 RIVGGAVSSEGEWPWQASLQVRG---RHICGGALIADRWVITAAHCFQEDSMASTVLWTV 632
RIVGG S GEWPWQ +L RH+CGG++I ++W++TAAHCF + S + V
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFY--GVESPKILRV 444
Query: 633 FLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPAR 692
+ G + Q+ F V +++H ++ YD+ALL+L+ V + + RP+CLP++
Sbjct: 445 YSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSK 504
Query: 693 SHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYR-YQVTPRMLCAGYR 751
CW+TGWG + I N LQK + L+ + C + YR +++T +M+CAGYR
Sbjct: 505 GDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYR 564
Query: 752 KGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWI 806
+G KDAC+GDSGGPL CK + W L G+ SWG GC + GVYT + + WI
Sbjct: 565 EGGKDACKGDSGGPLSCKH-NEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 618
>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
sapiens]
Length = 418
Score = 191 bits (485), Expect = 2e-48
Identities = 97/234 (41%), Positives = 138/234 (58%), Gaps = 8/234 (3%)
Query: 575 SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFL 634
+RI G ++ + WPWQASLQ H CG LI++ W++TAAHCFQ+ + WTV
Sbjct: 185 NRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQK--YKNPHQWTVSF 242
Query: 635 GKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSH 694
G P + V R ++H + + +YD+A++Q+ V S +R +CLP S
Sbjct: 243 GTKIN----PPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEASA 298
Query: 695 FFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSE--VYRYQVTPRMLCAGYRK 752
F+P L ITG+GAL GG N L++ V++I D+C + VY + P M CAGY +
Sbjct: 299 SFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAGYME 358
Query: 753 GKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWI 806
G DAC+GDSGGPLV + L W+L G+VSWG CG+ + GVYT++T +WI
Sbjct: 359 GIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWI 412
>gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo
sapiens]
Length = 421
Score = 191 bits (485), Expect = 2e-48
Identities = 97/234 (41%), Positives = 138/234 (58%), Gaps = 8/234 (3%)
Query: 575 SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFL 634
+RI G ++ + WPWQASLQ H CG LI++ W++TAAHCFQ+ + WTV
Sbjct: 188 NRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQK--YKNPHQWTVSF 245
Query: 635 GKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSH 694
G P + V R ++H + + +YD+A++Q+ V S +R +CLP S
Sbjct: 246 GTKIN----PPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEASA 301
Query: 695 FFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSE--VYRYQVTPRMLCAGYRK 752
F+P L ITG+GAL GG N L++ V++I D+C + VY + P M CAGY +
Sbjct: 302 SFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAGYME 361
Query: 753 GKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWI 806
G DAC+GDSGGPLV + L W+L G+VSWG CG+ + GVYT++T +WI
Sbjct: 362 GIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWI 415
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 191 bits (484), Expect = 3e-48
Identities = 93/235 (39%), Positives = 139/235 (59%), Gaps = 8/235 (3%)
Query: 576 RIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLG 635
RI+GG + EG WPWQ SL++ H CGG+LI + W++TAAHCF+ +S + T +
Sbjct: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGIS 245
Query: 636 KVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHF 695
+ R +V +L+H ++ +H+ D+AL++L++ V + + VCLPA +
Sbjct: 246 TTFPKLR------MRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQN 299
Query: 696 FEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQ--VTPRMLCAGYRKG 753
PG ++TGWGA G L++ V++I D+C+ + Y + MLCAG +G
Sbjct: 300 IPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQG 359
Query: 754 KKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQ 808
DACQGDSGGPLV + WF+ G+VSWG CG P+ GVYTR+T + WI+Q
Sbjct: 360 GVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQ 414
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 189 bits (481), Expect = 7e-48
Identities = 103/245 (42%), Positives = 142/245 (57%), Gaps = 9/245 (3%)
Query: 568 CG-LQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAS 626
CG +G SSRIVGG +S +WPWQASLQ +G H+CGG++I W+ITAAHC + +
Sbjct: 207 CGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPK 266
Query: 627 TVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRP 686
+ WT+ +G V S V +++ H ++ D+AL++L P+ + ++P
Sbjct: 267 S--WTIQVGLVSLLDN--PAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQP 322
Query: 687 VCLPARSHFFEPGLHCWITGWGALREG-GPISNALQKVDVQLIPQDLCS--EVYRYQVTP 743
VCLP F G CW +GWGA +G G S L V LI +C+ +VY ++P
Sbjct: 323 VCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISP 382
Query: 744 RMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVI 803
MLCAGY G D+CQGDSGGPLVC+ W L G S+G+GC N GVYTR+T +
Sbjct: 383 SMLCAGYLTGGVDSCQGDSGGPLVCQE-RRLWKLVGATSFGIGCAEVNKPGVYTRVTSFL 441
Query: 804 SWIQQ 808
WI +
Sbjct: 442 DWIHE 446
Score = 37.7 bits (86), Expect = 0.043
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 491 CRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQC 525
C ++C+ CI L CDG DC +G DE +C
Sbjct: 73 CSGKYRCRSSFKCIELIARCDGVSDCKDGEDEYRC 107
Score = 36.2 bits (82), Expect = 0.13
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 10/64 (15%)
Query: 430 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPA---CDGVKDCPNGLDE 486
I I + I G+ +H+ C G++ C + C+ CDGV DC +G DE
Sbjct: 52 IVIGIIALILALAIGLGIHFD-------CSGKYRCRSSFKCIELIARCDGVSDCKDGEDE 104
Query: 487 RNCV 490
CV
Sbjct: 105 YRCV 108
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 186 bits (473), Expect = 6e-47
Identities = 133/411 (32%), Positives = 187/411 (45%), Gaps = 89/411 (21%)
Query: 458 CPGEFLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPK------ 508
C + L N CV CDG DC + DE +CV T +S+ +
Sbjct: 655 CQDDELECANHACVSRDLWCDGEADCSDSSDEWDCV---TLSINVNSSSFLMVHRAATEH 711
Query: 509 -VC-DGQPDCLNGSDEEQCQEGVPCGTFTFQ----------------------------- 537
VC DG + L+ +Q G P T Q
Sbjct: 712 HVCADGWQEILSQLACKQMGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVN 771
Query: 538 ---CEDRS-----CVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWP 589
CE RS C K+ C RP R + RI+GG S G WP
Sbjct: 772 GQSCESRSKISLLCTKQ---DCGRRPAAR--------------MNKRILGGRTSRPGRWP 814
Query: 590 WQASLQVR-GRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLG-------KVWQNS 641
WQ SLQ HICG LIA +WV+T AHCF+ A+ +W V LG V+ +
Sbjct: 815 WQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAA--VWKVVLGINNLDHPSVFMQT 872
Query: 642 RWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLH 701
R+ V ++LHP + DYD+++++L + + VRPVCLP + EP +
Sbjct: 873 RF-------VKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLPNPEQWLEPDTY 925
Query: 702 CWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQ-VTPRMLCAGYRKGKKDACQG 760
C+ITGWG + G + LQ+ +V++I + C + + +T RM+CAGY G D+C G
Sbjct: 926 CYITGWGHM--GNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVDSCMG 983
Query: 761 DSGGPLVCKALSGRWFLAGLVSWGLGC-GRPNYFGVYTRITGVISWIQQVV 810
DSGGPLVC+ GRW L GL SWG C + GVY+ ++ + WI++ +
Sbjct: 984 DSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQI 1034
Score = 79.3 bits (194), Expect = 1e-14
Identities = 51/149 (34%), Positives = 72/149 (48%), Gaps = 23/149 (15%)
Query: 433 NFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVN--------GLCVP---ACDGVKDCP 481
NF + PG ++ YN D E C+ + G C+ CDG DC
Sbjct: 274 NFLCASGICIPG-KLQCNGYNDCDDWSDEAHCNCSENLFHCHTGKCLNYSLVCDGYDDCG 332
Query: 482 NGLDERNCVCRATFQCK-EDSTCISLPKVCDGQPDCLNGSDEEQCQ---EGVPCGTFTFQ 537
+ DE+NC C T + + D CI++ VCDG DC++ SDE C +G+ +
Sbjct: 333 DLSDEQNCDCNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHSQGL------VE 386
Query: 538 CEDRSCVKKPNPQCDGRPDCRDGSDEEHC 566
C + C+ QCDG DC+DGSDEE+C
Sbjct: 387 CRNGQCIPSTF-QCDGDEDCKDGSDEENC 414
Score = 79.0 bits (193), Expect = 2e-14
Identities = 43/113 (38%), Positives = 57/113 (50%), Gaps = 10/113 (8%)
Query: 459 PGEFLCSVNGLCVPA---CDGVKDCPNGLDERNCVC--RATFQCKEDSTCISLPKVCDGQ 513
P F C +G CV A CDG DC + DE NC C R ++C + C+ +CDG
Sbjct: 582 PSHFKCR-SGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDGF 640
Query: 514 PDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHC 566
PDC + DE+ C C +C + +CV + + CDG DC D SDE C
Sbjct: 641 PDCPDYMDEKNCSF---CQDDELECANHACVSR-DLWCDGEADCSDSSDEWDC 689
Score = 75.5 bits (184), Expect = 2e-13
Identities = 43/115 (37%), Positives = 57/115 (49%), Gaps = 10/115 (8%)
Query: 462 FLCSVNGLCVPA---CDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLN 518
FLC+ +G+C+P C+G DC + DE +C C C++ VCDG DC +
Sbjct: 275 FLCA-SGICIPGKLQCNGYNDCDDWSDEAHCNCSENLFHCHTGKCLNYSLVCDGYDDCGD 333
Query: 519 GSDEEQCQEGVPCG-TFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQG 572
SDE+ C C T +C D C+ CDG DC D SDE +C C QG
Sbjct: 334 LSDEQNCD----CNPTTEHRCGDGRCIAM-EWVCDGDHDCVDKSDEVNCSCHSQG 383
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 10/107 (9%)
Query: 464 CSVN-GLCVPACDGVKDCPNGLDERNCVCRAT-FQCKEDSTCISLPKVCDGQPDCLNGSD 521
C VN G +P C + C + + V Q ED+ C P+ CL
Sbjct: 518 CDVNTGEHIPPCRAL--CEHSKERCESVLGIVGLQWPEDTDCSQFPEENSDNQTCL--MP 573
Query: 522 EEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDC 568
+E +E C F+C CV +CDG+ DC D SDEE+C C
Sbjct: 574 DEYVEE---CSPSHFKCRSGQCVLASR-RCDGQADCDDDSDEENCGC 616
Score = 41.2 bits (95), Expect = 0.004
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 5/69 (7%)
Query: 467 NGLCVPA---CDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPKV--CDGQPDCLNGSD 521
NG C+P+ CDG +DC +G DE NC T + D C+ P + C G C +
Sbjct: 389 NGQCIPSTFQCDGDEDCKDGSDEENCSVIQTSCQEGDQRCLYNPCLDSCGGSSLCDPNNS 448
Query: 522 EEQCQEGVP 530
C + P
Sbjct: 449 LNNCSQCEP 457
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,385,768
Number of Sequences: 37866
Number of extensions: 1698383
Number of successful extensions: 5563
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 219
Number of HSP's successfully gapped in prelim test: 120
Number of HSP's that attempted gapping in prelim test: 3651
Number of HSP's gapped (non-prelim): 938
length of query: 811
length of database: 18,247,518
effective HSP length: 111
effective length of query: 700
effective length of database: 14,044,392
effective search space: 9831074400
effective search space used: 9831074400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.