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Search of human proteins with 239047271
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239047271 autophagy related 2A [Homo sapiens]
(1938 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239047271 autophagy related 2A [Homo sapiens] 3916 0.0
gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] 1457 0.0
gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens] 50 2e-05
gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens] 50 2e-05
gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens] 47 1e-04
gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens] 47 1e-04
gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens] 47 1e-04
gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens] 47 1e-04
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 42 0.004
gi|116268091 PHD finger protein 23 [Homo sapiens] 41 0.010
gi|18426904 Werner helicase interacting protein isoform 2 [Homo ... 40 0.022
gi|18426902 Werner helicase interacting protein isoform 1 [Homo ... 40 0.022
gi|190341107 N-acetyltransferase 12 [Homo sapiens] 39 0.049
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 39 0.064
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 39 0.064
gi|54860079 nadrin isoform 1 [Homo sapiens] 39 0.064
gi|54860105 nadrin isoform 2 [Homo sapiens] 39 0.064
gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ... 39 0.064
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 38 0.084
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 38 0.084
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 38 0.11
gi|95147333 phospholipase C, beta 2 [Homo sapiens] 37 0.14
gi|13699803 WAS protein family, member 3 [Homo sapiens] 37 0.14
gi|116517292 cut-like 2 [Homo sapiens] 37 0.19
gi|60460889 Myb protein P42POP [Homo sapiens] 37 0.19
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 37 0.24
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 37 0.24
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] 37 0.24
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 36 0.32
gi|27436925 synoviolin 1 isoform a [Homo sapiens] 36 0.42
>gi|239047271 autophagy related 2A [Homo sapiens]
Length = 1938
Score = 3916 bits (10155), Expect = 0.0
Identities = 1938/1938 (100%), Positives = 1938/1938 (100%)
Query: 1 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN 60
MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN
Sbjct: 1 MSRWLWPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVN 60
Query: 61 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS 120
EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS
Sbjct: 61 EVLESMESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQS 120
Query: 121 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH 180
WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH
Sbjct: 121 WASCMTTSLQLAQECLRDGLPEPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEH 180
Query: 181 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP 240
SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP
Sbjct: 181 SPGDGERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEELP 240
Query: 241 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL 300
AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL
Sbjct: 241 AQEEPPEPPLQIGSCSGYMELMVKLKQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQEL 300
Query: 301 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD 360
LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD
Sbjct: 301 LSAVSLTDHEGLADKLNKSRPLGAEDLWLIEQDLNQQLQAGAVAEPLSPDPLTNPLLNLD 360
Query: 361 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT 420
NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT
Sbjct: 361 NTDLFFSMAGLTSSVASALSELSLSDVDLASSVRSDMASRRLSAQAHPAGKMAPNPLLDT 420
Query: 421 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ 480
MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ
Sbjct: 421 MRPDSLLKMTLGGVTLTLLQTSAPSSGPPDLATHFFTEFDATKDGPFGSRDFHHLRPRFQ 480
Query: 481 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL 540
RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL
Sbjct: 481 RACPCSHVRLTGTAVQLSWELRTGSRGRRTTSMEVHFGQLEVLECLWPRGTSEPEYTEIL 540
Query: 541 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL 600
TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL
Sbjct: 541 TFPGTLGSQASARPCAHLRHTQILRRVPKSRPRRSVACHCHSELALDLANFQADVELGAL 600
Query: 601 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA 660
DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA
Sbjct: 601 DRLAALLRLATVPAEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPDPWA 660
Query: 661 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK 720
GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK
Sbjct: 661 GQAVRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIYEDGGKPPVPCLRVSK 720
Query: 721 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK 780
ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK
Sbjct: 721 ALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELREPEPSPFSSK 780
Query: 781 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND 840
RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND
Sbjct: 781 RTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEVYESIYNRINND 840
Query: 841 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH 900
LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH
Sbjct: 841 LLMWEPADLLPTPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFDLTPDSDSDDEDAH 900
Query: 901 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL 960
FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL
Sbjct: 901 FFSVGASGGPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKDEGGKRLEAVHGELVL 960
Query: 961 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT 1020
DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT
Sbjct: 961 DMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSHLDLPSFAPPAQLAPT 1020
Query: 1021 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL 1080
IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL
Sbjct: 1021 IYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHKNVKEFLVTLRLHKATLRHYMAL 1080
Query: 1081 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT 1140
PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT
Sbjct: 1081 PEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYRPLYLPVRVLITAETFT 1140
Query: 1141 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST 1200
LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST
Sbjct: 1141 LSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVLDVDLLELVIKTWKGST 1200
Query: 1201 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKL 1260
EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKL
Sbjct: 1201 EGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKL 1260
Query: 1261 SESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGER 1320
SESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGER
Sbjct: 1261 SESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLPQASPISVYLFPGER 1320
Query: 1321 SGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPV 1380
SGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPV
Sbjct: 1321 SGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPV 1380
Query: 1381 VTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHP 1440
VTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHP
Sbjct: 1381 VTQLHPGPIVVRDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHP 1440
Query: 1441 GHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP 1500
GHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP
Sbjct: 1441 GHRARTGLSGPRSSPSRCSGPNRPQNSWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP 1500
Query: 1501 ATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTI 1560
ATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTI
Sbjct: 1501 ATGPAAPSQELEERPLSRQVFIVQELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTI 1560
Query: 1561 KALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEA 1620
KALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEA
Sbjct: 1561 KALHVAPTTNLGGPECCLRVSLMPLRLNVDQDALFFLKDFFTSLVAGINPVVPGETSAEA 1620
Query: 1621 RPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYH 1680
RPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYH
Sbjct: 1621 RPETRAQPSSPLEGQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYH 1680
Query: 1681 GKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQ 1740
GKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQ
Sbjct: 1681 GKHVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQ 1740
Query: 1741 LPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALEL 1800
LPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALEL
Sbjct: 1741 LPGLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALEL 1800
Query: 1801 SNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVRE 1860
SNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVRE
Sbjct: 1801 SNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLRRGQQPADLREGVAKAYDTVRE 1860
Query: 1861 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV 1920
GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV
Sbjct: 1861 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV 1920
Query: 1921 PDAHKDHALKWRSDSAQD 1938
PDAHKDHALKWRSDSAQD
Sbjct: 1921 PDAHKDHALKWRSDSAQD 1938
>gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens]
Length = 2078
Score = 1457 bits (3771), Expect = 0.0
Identities = 891/2112 (42%), Positives = 1219/2112 (57%), Gaps = 225/2112 (10%)
Query: 6 WPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLES 65
WP+S +K+R CRYLL YLGHF QE LSL+QLSLDLY+G+ +L + L+ W +NE+LES
Sbjct: 3 WPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILES 62
Query: 66 MESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCM 125
++PLE+ EGF+ SI ++VPW +LL D+C + V GL++ +PR PA G+ + W+S M
Sbjct: 63 ADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGS-EPMYWSSFM 121
Query: 126 TTSLQLAQECLRDGLP-EPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGD 184
T+S+QLA+ECL L E E QP EGLE FA+TIETVLRR+KVTF+DTV+R+EH P +
Sbjct: 122 TSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPEN 181
Query: 185 GERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEEL----- 239
+ G A+E+R++R YCDE + S ++VHQP AF HKLLQL+GV L ++E
Sbjct: 182 SKTGTALEIRIERTVYCDETADESSG---INVHQPTAFAHKLLQLSGVSLFWDEFSASAK 238
Query: 240 --------PAQEEP--------------------------PEPPLQIGSCSGYMELMVKL 265
P + EP P P+QIG G +EL + L
Sbjct: 239 SSPVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTL 298
Query: 266 KQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHE---GLADKLNKSRPL 322
KQNE PG KL+V GQ+ S+HLLL+PRQ+ L ++L+A++ ++ GLA+K K+RP+
Sbjct: 299 KQNEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPM 358
Query: 323 GAEDLWLIEQDLNQ------QLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVA 376
ED + I+ +LN+ L G +E + T + ++FFSMA + S +
Sbjct: 359 QQEDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADMDMSHS 418
Query: 377 -SALSELSLS-----DVDLASSVRSDMASRRLSA---------------------QAHPA 409
S+L L ++ L S+ + A LSA P+
Sbjct: 419 LSSLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPS 478
Query: 410 GKMAPNPL-----------LDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPD-------- 450
+ P PL +D RP+ + ++ +G ++++L S PP+
Sbjct: 479 NLVHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLS--PPETSQNLNPL 536
Query: 451 --LATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGR 508
+A FFT + F + DF R F AC H+R GT +++S+E R S R
Sbjct: 537 TPMAVAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASR 596
Query: 509 RTTSMEVHFGQLEVLECLWPRG--TSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRR 566
S ++ GQ+E LECL+P + P YTE+LTF + + + C L + R
Sbjct: 597 YF-STDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENR 655
Query: 567 VPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALL---RLATVP---------- 613
P+ R + +EL + L ++++ +DRL +LL +LATV
Sbjct: 656 GPQGNQARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSY 715
Query: 614 --------AEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPD--PWAGQA 663
A L PA + +V +++ P L +RFPI DLR + + PW ++
Sbjct: 716 NKHISLHKAFTEVFLDDSHSPANCRISV-QVATPALNLSVRFPIPDLRSDQERGPWFKKS 774
Query: 664 VRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIY-EDGGKPPVPCLRVSKAL 722
++ E L L ++ +F++E G P LELT +L G + E+ G P + VS +
Sbjct: 775 LQKEILYLAFTDLEFKTEFIGG-STPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGV 833
Query: 723 DPKSTGRKYF-LPQVVVTVNPQSSSTQWE-VAPEKGEELE-----------LSVESPCEL 769
D +T F P++V+ +NP + + E +A E+ EE + S++ C+L
Sbjct: 834 DGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDL 893
Query: 770 REPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEV 829
R P PSPFSS+R M+E E+MV+PGDP EM FQ + ++ S LE+ LP++++ LP+K
Sbjct: 894 RRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSF 953
Query: 830 YESIYNRINNDLLMWEPADLLP--TPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFD 887
YE +YNRI NDLL+WEP P T + + G S + K SAFK A +D
Sbjct: 954 YEKLYNRIFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYD 1013
Query: 888 LTPDSDSDDEDAHFFSVGASG--GPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKD 945
+S S++E +FS + ++ + + QS S L+ + G I + K
Sbjct: 1014 --EESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQ 1071
Query: 946 EGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSH 1005
+ G LE HGE L+ G+LF V++Y G Y CL + +LYH+ V+ LP+
Sbjct: 1072 DNGDLLENKHGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTE 1131
Query: 1006 LDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHK-NVKEFL 1064
LPS P L PTIY SEE + +S G G +MLS AV+I D + N KEFL
Sbjct: 1132 TRLPSSTRPHWLEPTIYSSEEDGLSKTSSDGVG-GDSLNMLSVAVKILSDKSESNTKEFL 1190
Query: 1065 VTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYR 1124
+ + L ATL+H M SWH Q+L FL++ D+PVLGY PPT T H HL+SC++DYR
Sbjct: 1191 IAVGLKGATLQHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYR 1250
Query: 1125 PLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVL 1184
PLYLP+R L+T ETF++SS++ +D S+ LR ILD++AL+LSDKC T++L RDYV V+
Sbjct: 1251 PLYLPIRSLLTVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVM 1310
Query: 1185 DVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLH 1244
D+ LLEL I K ++G+ ++P FEL CS++VVH+ +C+DSCA L+NL+QY+ S GDL
Sbjct: 1311 DMGLLELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQ 1370
Query: 1245 PPPRPP---------SPTEIAGQKLSESPASLPSCPPVETALINQRDL-ADAL--LDTER 1292
P + S + +G+ S P P + ++ RDL +DA+ +D ++
Sbjct: 1371 TPNKADMKPGAFQRRSKVDSSGRSSSRGPV----LPEADQQML--RDLMSDAMEEIDMQQ 1424
Query: 1293 SLRELAQPSGGHLPQASPI------SVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKED 1346
+ + G L + S I ++LFP E S P + +
Sbjct: 1425 GTSSVKPQANGVLDEKSQIQEPCCSDLFLFPDESGNVSQESGP---------TYASFSHH 1475
Query: 1347 EREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLL 1406
+ G ++D+FCIL AP + ++ EPV+ + IV+RD YFS P+ TD
Sbjct: 1476 FISDAMTGVPTENDDFCILFAPKAAMQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTS 1535
Query: 1407 RAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQN 1466
+AP HFP+P R V++EVSLVWHLYGG+DFG P P SSPS P R
Sbjct: 1536 KAPLHFPIPVIRYVVKEVSLVWHLYGGKDFGTVPPTSPAKSYISPHSSPSHT--PTRHGR 1593
Query: 1467 SWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAP--SQELEERPLSRQVFIVQ 1524
+ GG GR H LMEIQLSKV FQHEVYP P P L E P+SRQVFIVQ
Sbjct: 1594 N-TVCGGKGRNHDFLMEIQLSKVKFQHEVYP------PCKPDCDSSLSEHPVSRQVFIVQ 1646
Query: 1525 ELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMP 1584
+LE+RDRLA+SQ+NKFLYL+ S+ MPR+AHSNMLT+KALHV P + ECCLRVSLMP
Sbjct: 1647 DLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNMLTVKALHVCPESGRSPQECCLRVSLMP 1706
Query: 1585 LRLNVDQDALFFLKDFFTSLVAGI------NPVV------------PGETSAEARPETRA 1626
LRLN+DQDALFFLKDFFTSL A + +P V P S P
Sbjct: 1707 LRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEVKKSPGADVTCSLPRHLSTSKEPNLVI 1766
Query: 1627 QPSSPLE----GQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGK 1682
S P + A VE E + QP++FREFRFTSEVPI LDYHGK
Sbjct: 1767 SFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEASFRDQPVFFREFRFTSEVPIRLDYHGK 1826
Query: 1683 HVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLP 1742
HV+MDQ GT AG+LIGLAQLNCSELKLKRL RHGLLGVDK+ YA+ EWL DI+KNQLP
Sbjct: 1827 HVSMDQ-GTLAGILIGLAQLNCSELKLKRLSYRHGLLGVDKLFSYAITEWLNDIKKNQLP 1885
Query: 1743 GLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSN 1802
G+LGGVGPMHS+VQL QG +DL+WLPIEQYRKDGR++RG QRGAASFG+STA AALEL+N
Sbjct: 1886 GILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTN 1945
Query: 1803 RLVQAIQATAETVYDILSPAAPVSRSLQDKRSAR--RLRRGQQPADLREGVAKAYDTVRE 1860
R+VQ IQA AET YD++SP + S++ K++ R R QP DLREGVAKAY V+E
Sbjct: 1946 RMVQTIQAAAETAYDMVSPG---TLSIEPKKTKRFPHHRLAHQPVDLREGVAKAYSVVKE 2002
Query: 1861 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV 1920
GI DTAQTI + A+R HE +G+TGAVG V+RQ+PP VVKPLI+ATEATS++LGGMRNQI
Sbjct: 2003 GITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVKPLIVATEATSNVLGGMRNQIR 2062
Query: 1921 PDAHKDHALKWR 1932
PD +D + KWR
Sbjct: 2063 PDVRQDESQKWR 2074
>gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens]
Length = 4363
Score = 50.4 bits (119), Expect = 2e-05
Identities = 29/96 (30%), Positives = 53/96 (55%), Gaps = 5/96 (5%)
Query: 14 ERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELV 73
E + ++L+ YLG + +L+ DQLS+ L KG+V L ++ L+ + L+ +E P E+
Sbjct: 3 EGLVAWVLNTYLGKYVN-NLNTDQLSVALLKGAVELENLPLK----KDALKELELPFEVK 57
Query: 74 EGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRR 109
GF+G + + +P+ D + +S L L P +
Sbjct: 58 AGFIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEK 93
>gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens]
Length = 4388
Score = 50.4 bits (119), Expect = 2e-05
Identities = 29/96 (30%), Positives = 53/96 (55%), Gaps = 5/96 (5%)
Query: 14 ERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELV 73
E + ++L+ YLG + +L+ DQLS+ L KG+V L ++ L+ + L+ +E P E+
Sbjct: 3 EGLVAWVLNTYLGKYVN-NLNTDQLSVALLKGAVELENLPLK----KDALKELELPFEVK 57
Query: 74 EGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRR 109
GF+G + + +P+ D + +S L L P +
Sbjct: 58 AGFIGKVTLQIPFYRPHVDPWVISISSLHLIGAPEK 93
>gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]
Length = 3095
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/189 (20%), Positives = 88/189 (46%), Gaps = 10/189 (5%)
Query: 12 VKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLE 71
V E V +L+ +LG + + L QLSL ++KG+VAL+++ ++ L ++ P +
Sbjct: 2 VFESVVVDVLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIK----ENALSQLDVPFK 56
Query: 72 LVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP-RRGPAPGAADSQSWASCMTTSLQ 130
+ G +G++++ +PW L T + + L + P R + + L+
Sbjct: 57 VKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELK 116
Query: 131 LAQECLRDGLPEPSEPPQPLEGLEMFAQTIET-VLRRIKVTFLDTVVRVEHSPGDGERGV 189
+E + + + P E + FA+ + T +++ ++V +R E + ++ +
Sbjct: 117 RIEEAKQKVVDQEQHLP---EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPL 173
Query: 190 AVEVRVQRL 198
+ + +Q L
Sbjct: 174 SFGISLQNL 182
Score = 35.4 bits (80), Expect = 0.55
Identities = 29/137 (21%), Positives = 50/137 (36%)
Query: 1780 RGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLR 1839
+G +G F A L V + A + ++ +D + RR
Sbjct: 2889 QGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREA 2948
Query: 1840 RGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVK 1899
+QPA REG+ + + G + I +G ++ G G GV + L V +
Sbjct: 2949 MNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVAR 3008
Query: 1900 PLILATEATSSLLGGMR 1916
P + SS G++
Sbjct: 3009 PTGGIIDMASSTFQGIK 3025
>gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]
Length = 3069
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/189 (20%), Positives = 88/189 (46%), Gaps = 10/189 (5%)
Query: 12 VKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLE 71
V E V +L+ +LG + + L QLSL ++KG+VAL+++ ++ L ++ P +
Sbjct: 2 VFESVVVDVLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIK----ENALSQLDVPFK 56
Query: 72 LVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP-RRGPAPGAADSQSWASCMTTSLQ 130
+ G +G++++ +PW L T + + L + P R + + L+
Sbjct: 57 VKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELK 116
Query: 131 LAQECLRDGLPEPSEPPQPLEGLEMFAQTIET-VLRRIKVTFLDTVVRVEHSPGDGERGV 189
+E + + + P E + FA+ + T +++ ++V +R E + ++ +
Sbjct: 117 RIEEAKQKVVDQEQHLP---EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPL 173
Query: 190 AVEVRVQRL 198
+ + +Q L
Sbjct: 174 SFGISLQNL 182
Score = 35.4 bits (80), Expect = 0.55
Identities = 29/137 (21%), Positives = 50/137 (36%)
Query: 1780 RGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLR 1839
+G +G F A L V + A + ++ +D + RR
Sbjct: 2889 QGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREA 2948
Query: 1840 RGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVK 1899
+QPA REG+ + + G + I +G ++ G G GV + L V +
Sbjct: 2949 MNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVAR 3008
Query: 1900 PLILATEATSSLLGGMR 1916
P + SS G++
Sbjct: 3009 PTGGIIDMASSTFQGIK 3025
>gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]
Length = 3174
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/189 (20%), Positives = 88/189 (46%), Gaps = 10/189 (5%)
Query: 12 VKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLE 71
V E V +L+ +LG + + L QLSL ++KG+VAL+++ ++ L ++ P +
Sbjct: 2 VFESVVVDVLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIK----ENALSQLDVPFK 56
Query: 72 LVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP-RRGPAPGAADSQSWASCMTTSLQ 130
+ G +G++++ +PW L T + + L + P R + + L+
Sbjct: 57 VKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELK 116
Query: 131 LAQECLRDGLPEPSEPPQPLEGLEMFAQTIET-VLRRIKVTFLDTVVRVEHSPGDGERGV 189
+E + + + P E + FA+ + T +++ ++V +R E + ++ +
Sbjct: 117 RIEEAKQKVVDQEQHLP---EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPL 173
Query: 190 AVEVRVQRL 198
+ + +Q L
Sbjct: 174 SFGISLQNL 182
Score = 35.4 bits (80), Expect = 0.55
Identities = 29/137 (21%), Positives = 50/137 (36%)
Query: 1780 RGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLR 1839
+G +G F A L V + A + ++ +D + RR
Sbjct: 2889 QGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREA 2948
Query: 1840 RGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVK 1899
+QPA REG+ + + G + I +G ++ G G GV + L V +
Sbjct: 2949 MNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVAR 3008
Query: 1900 PLILATEATSSLLGGMR 1916
P + SS G++
Sbjct: 3009 PTGGIIDMASSTFQGIK 3025
>gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]
Length = 3135
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/189 (20%), Positives = 88/189 (46%), Gaps = 10/189 (5%)
Query: 12 VKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLE 71
V E V +L+ +LG + + L QLSL ++KG+VAL+++ ++ L ++ P +
Sbjct: 2 VFESVVVDVLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIK----ENALSQLDVPFK 56
Query: 72 LVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP-RRGPAPGAADSQSWASCMTTSLQ 130
+ G +G++++ +PW L T + + L + P R + + L+
Sbjct: 57 VKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELK 116
Query: 131 LAQECLRDGLPEPSEPPQPLEGLEMFAQTIET-VLRRIKVTFLDTVVRVEHSPGDGERGV 189
+E + + + P E + FA+ + T +++ ++V +R E + ++ +
Sbjct: 117 RIEEAKQKVVDQEQHLP---EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPL 173
Query: 190 AVEVRVQRL 198
+ + +Q L
Sbjct: 174 SFGISLQNL 182
Score = 35.4 bits (80), Expect = 0.55
Identities = 29/137 (21%), Positives = 50/137 (36%)
Query: 1780 RGLQRGAASFGSSTASAALELSNRLVQAIQATAETVYDILSPAAPVSRSLQDKRSARRLR 1839
+G +G F A L V + A + ++ +D + RR
Sbjct: 2850 QGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREA 2909
Query: 1840 RGQQPADLREGVAKAYDTVREGILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVK 1899
+QPA REG+ + + G + I +G ++ G G GV + L V +
Sbjct: 2910 MNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVAR 2969
Query: 1900 PLILATEATSSLLGGMR 1916
P + SS G++
Sbjct: 2970 PTGGIIDMASSTFQGIK 2986
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 42.4 bits (98), Expect = 0.004
Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 36/135 (26%)
Query: 1238 MSTGDLHPPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDLADALLDTERSLREL 1297
+ TGD P P PP+P+ + +S PS PP
Sbjct: 177 LGTGDGGPAP-PPAPSSASSSPSPSPSSSSPSPPPPPP---------------------- 213
Query: 1298 AQPSGGHLPQASPISVY--LFPGERSGAPPPSP--------PVGG-PAGSLGSCSEEKED 1346
P P A +Y P + + +PPP+P P G P+ S G+ S E+E+
Sbjct: 214 --PPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEE 271
Query: 1347 EREEEGDGDTLDSDE 1361
E EEE + + D +E
Sbjct: 272 EEEEEEEEEEEDEEE 286
Score = 35.0 bits (79), Expect = 0.71
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 10/93 (10%)
Query: 1273 VETALINQRDLADALLDTERSLRELAQP--SGGHLPQASPISVYLFPGERSGAPPPSPPV 1330
+E A + R A L+ + +P S G P P S+ L PG S P S P+
Sbjct: 1113 MEEANLASRAKAQELIQATNQILSHRKPPSSLGMTPAPVPTSLGLPPGPSSYLLPGSLPL 1172
Query: 1331 GG-------PAGSLGSCSEEKEDEREEEGDGDT 1356
GG P G L + S+++E EG GDT
Sbjct: 1173 GGCGSTPPTPTG-LAATSDKREGSSSSEGRGDT 1204
>gi|116268091 PHD finger protein 23 [Homo sapiens]
Length = 403
Score = 41.2 bits (95), Expect = 0.010
Identities = 57/201 (28%), Positives = 81/201 (40%), Gaps = 34/201 (16%)
Query: 1224 ADSCALLVNLLQYVMSTGDLHPPP--RPPSPTEIAGQKLSESPASLPSCPPVETALINQR 1281
A A L+ ++ S DL P P SPT + S PA+L P ++Q
Sbjct: 121 APDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLT--HTSRPPAALTPVP------LSQG 172
Query: 1282 DLADALLDTERSLRELAQPSGGHL-----PQASP------------ISVYLFPGERSGA- 1323
DL+ +R R+L +G P+ +P L ER
Sbjct: 173 DLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRL 232
Query: 1324 PPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQ 1383
PPP PP P+ + S EE+E+E EEE + T+ E P L PP P T
Sbjct: 233 PPPGPPQAPPSDT-DSEEEEEEEEEEEEEEMATVVGGE---APVPVLPTPPEAPRPPAT- 287
Query: 1384 LHPGPIVVRDGYFSRPIGSTD 1404
+HP + D S+ +GST+
Sbjct: 288 VHPEGVPPADSE-SKEVGSTE 307
>gi|18426904 Werner helicase interacting protein isoform 2 [Homo
sapiens]
Length = 640
Score = 40.0 bits (92), Expect = 0.022
Identities = 41/143 (28%), Positives = 57/143 (39%), Gaps = 6/143 (4%)
Query: 1219 HVHSCADSCALLVNLLQYVMSTGDLHPPPRP--PSPTEIAGQKLSESPA-SLPSCPPVET 1275
H++S D C LL + G R PSP ++LSES A P+ P
Sbjct: 31 HINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAE 90
Query: 1276 ALINQRDLADALLDTE--RSLRELAQPSGGHLPQASPISVYLFPGER-SGAPPPSPPVGG 1332
+ + + D +TE S PSG L P++ PG + SG P + G
Sbjct: 91 SSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAG 150
Query: 1333 PAGSLGSCSEEKEDEREEEGDGD 1355
A E ++E E GDGD
Sbjct: 151 SASPRSWDEAEAQEEEEAVGDGD 173
>gi|18426902 Werner helicase interacting protein isoform 1 [Homo
sapiens]
Length = 665
Score = 40.0 bits (92), Expect = 0.022
Identities = 41/143 (28%), Positives = 57/143 (39%), Gaps = 6/143 (4%)
Query: 1219 HVHSCADSCALLVNLLQYVMSTGDLHPPPRP--PSPTEIAGQKLSESPA-SLPSCPPVET 1275
H++S D C LL + G R PSP ++LSES A P+ P
Sbjct: 31 HINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAE 90
Query: 1276 ALINQRDLADALLDTE--RSLRELAQPSGGHLPQASPISVYLFPGER-SGAPPPSPPVGG 1332
+ + + D +TE S PSG L P++ PG + SG P + G
Sbjct: 91 SSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAG 150
Query: 1333 PAGSLGSCSEEKEDEREEEGDGD 1355
A E ++E E GDGD
Sbjct: 151 SASPRSWDEAEAQEEEEAVGDGD 173
>gi|190341107 N-acetyltransferase 12 [Homo sapiens]
Length = 362
Score = 38.9 bits (89), Expect = 0.049
Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 9/47 (19%)
Query: 1317 PGERSGAPPPSPPVGG--------PAGS-LGSCSEEKEDEREEEGDG 1354
PG S PPP+PP PAG+ L CSE++ED+ E EG G
Sbjct: 6 PGPSSLLPPPAPPAPAAVEPRCPFPAGAALACCSEDEEDDEEHEGGG 52
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 38.5 bits (88), Expect = 0.064
Identities = 35/105 (33%), Positives = 44/105 (41%), Gaps = 18/105 (17%)
Query: 1239 STGDLHPPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDLA-DALLDTERSLRE- 1296
ST PPP PP P + G SP SLP TA+ L+ DA + L E
Sbjct: 596 STTPPPPPPPPPPPPPLPGGVCISSPPSLPG----GTAISPPPPLSGDATIPPPPPLPEG 651
Query: 1297 ------LAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAG 1335
+ P G +P P+ PG + PPP PP+ G AG
Sbjct: 652 VGIPSPSSLPGGTAIPPPPPL-----PGS-ARIPPPPPPLPGSAG 690
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 38.5 bits (88), Expect = 0.064
Identities = 35/105 (33%), Positives = 44/105 (41%), Gaps = 18/105 (17%)
Query: 1239 STGDLHPPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDLA-DALLDTERSLRE- 1296
ST PPP PP P + G SP SLP TA+ L+ DA + L E
Sbjct: 605 STTPPPPPPPPPPPPPLPGGVCISSPPSLPG----GTAISPPPPLSGDATIPPPPPLPEG 660
Query: 1297 ------LAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAG 1335
+ P G +P P+ PG + PPP PP+ G AG
Sbjct: 661 VGIPSPSSLPGGTAIPPPPPL-----PGS-ARIPPPPPPLPGSAG 699
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 38.5 bits (88), Expect = 0.064
Identities = 31/109 (28%), Positives = 40/109 (36%), Gaps = 25/109 (22%)
Query: 1244 HPPPRPPS---------------------PTEIAGQKLSESPASLPSCPPVETALINQRD 1282
HPPP+PP+ P+E ++ S +P P+ PP L Q
Sbjct: 713 HPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPT-PPSTPPLGKQNP 771
Query: 1283 LADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVG 1331
A E AQP G LP+ P+ P R PPP P G
Sbjct: 772 SLPAPQTLAGGNPETAQPHAGTLPRPRPVPK---PRNRPSVPPPPQPPG 817
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 38.5 bits (88), Expect = 0.064
Identities = 31/109 (28%), Positives = 40/109 (36%), Gaps = 25/109 (22%)
Query: 1244 HPPPRPPS---------------------PTEIAGQKLSESPASLPSCPPVETALINQRD 1282
HPPP+PP+ P+E ++ S +P P+ PP L Q
Sbjct: 635 HPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPT-PPSTPPLGKQNP 693
Query: 1283 LADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVG 1331
A E AQP G LP+ P+ P R PPP P G
Sbjct: 694 SLPAPQTLAGGNPETAQPHAGTLPRPRPVPK---PRNRPSVPPPPQPPG 739
>gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 [Homo
sapiens]
Length = 1461
Score = 38.5 bits (88), Expect = 0.064
Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 8/93 (8%)
Query: 1249 PPSPTEIAG--QKLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQPSGGHLP 1306
PPSP E Q+ P+S P PP + I RD L + S + + H
Sbjct: 1195 PPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAA 1254
Query: 1307 QASPISVYLFPGERSGAPPPSPPVGGPAGSLGS 1339
P PGE SG P P+PP P G S
Sbjct: 1255 PPPP------PGEHSGIPFPTPPPPPPPGEHSS 1281
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 38.1 bits (87), Expect = 0.084
Identities = 72/289 (24%), Positives = 102/289 (35%), Gaps = 68/289 (23%)
Query: 1245 PPPRPPSPTEIAGQKLS-----ESPASLPS----CPPVETALINQRDLADALLDTERSLR 1295
PP R PS I + E PA PS PP E R+L + TER +
Sbjct: 609 PPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQE------RNLPEG---TERPPK 659
Query: 1296 ELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGP------AGSLGSCSEEKEDERE 1349
+ G Q P V+++P +P P PP G P AG + + +R
Sbjct: 660 LCSSLPG----QGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRR 715
Query: 1350 EEGDGDTLDSDEFCILDAPGLGIPPRDGE---PVVTQLHPGPIVVRDGYFSRPIGSTDLL 1406
L PG +GE PV + L + R RP S +
Sbjct: 716 SHS------------LSRPGPTEGDAEGEAEGPVGSTLGSYATLTR-----RPGRSALVR 758
Query: 1407 RAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQN 1466
+P+ P P+ R R S L R P P + + +SGP P P ++
Sbjct: 759 TSPSVTPTPA-RGTPRSQSFA--LRARRKGPPPPPPKRLSSVSGPSPEP-----PPLDES 810
Query: 1467 SWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP--ATGPAAPSQELEE 1513
+G +G + L E P+EP PA P+ + EE
Sbjct: 811 PGPKEGATGPRRRTLSE----------PAGPSEPPGPPAPAGPASDTEE 849
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 38.1 bits (87), Expect = 0.084
Identities = 72/289 (24%), Positives = 102/289 (35%), Gaps = 68/289 (23%)
Query: 1245 PPPRPPSPTEIAGQKLS-----ESPASLPS----CPPVETALINQRDLADALLDTERSLR 1295
PP R PS I + E PA PS PP E R+L + TER +
Sbjct: 691 PPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQE------RNLPEG---TERPPK 741
Query: 1296 ELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGP------AGSLGSCSEEKEDERE 1349
+ G Q P V+++P +P P PP G P AG + + +R
Sbjct: 742 LCSSLPG----QGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRR 797
Query: 1350 EEGDGDTLDSDEFCILDAPGLGIPPRDGE---PVVTQLHPGPIVVRDGYFSRPIGSTDLL 1406
L PG +GE PV + L + R RP S +
Sbjct: 798 SHS------------LSRPGPTEGDAEGEAEGPVGSTLGSYATLTR-----RPGRSALVR 840
Query: 1407 RAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQN 1466
+P+ P P+ R R S L R P P + + +SGP P P ++
Sbjct: 841 TSPSVTPTPA-RGTPRSQSFA--LRARRKGPPPPPPKRLSSVSGPSPEP-----PPLDES 892
Query: 1467 SWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEP--ATGPAAPSQELEE 1513
+G +G + L E P+EP PA P+ + EE
Sbjct: 893 PGPKEGATGPRRRTLSE----------PAGPSEPPGPPAPAGPASDTEE 931
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 37.7 bits (86), Expect = 0.11
Identities = 60/227 (26%), Positives = 86/227 (37%), Gaps = 47/227 (20%)
Query: 1236 YVMSTGDLHPPPRPPSPTEIAGQKLSESP--ASLPSCPPVETALINQRDLADALLDTE-- 1291
+V +T PPP P P E ++L +P A P E + R D L +
Sbjct: 1166 WVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGD 1225
Query: 1292 ------------RSLRELAQPSGG------HLPQAS----PISVYLFPGERSGAPP---- 1325
R +L P G L + S P+++ FPG PP
Sbjct: 1226 PPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGA 1285
Query: 1326 PSPPVGGPAGSLGS---CSEEKEDEREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVT 1382
+ GG AG G+ E+ EDE E+E + DE APG PR P
Sbjct: 1286 DAGAAGGEAGGAGAPGPAEEDGEDEDEDE------EEDEEAA--APGAAAGPRG--PGRA 1335
Query: 1383 QLHPGPIVV--RDGYFSRPIGSTDLLRAPAHFPVPSTRVVLREVSLV 1427
+ P P+VV D +RP+ LL++P P + R+ +V
Sbjct: 1336 RAAPVPVVVSSADADAARPL--RGLLKSPRGADEPEDSELERKRKMV 1380
>gi|95147333 phospholipase C, beta 2 [Homo sapiens]
Length = 1185
Score = 37.4 bits (85), Expect = 0.14
Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 1318 GERSGAPPPSPPVGGP---AGSLGSCSEEKEDEREEEGDGDTLDSDE 1361
GE G+ PPS P G AG G+ EE+E E EEE + LD +E
Sbjct: 479 GEAEGSSPPSAPAGEGTVWAGEEGTELEEEEVEEEEEEESGNLDEEE 525
>gi|13699803 WAS protein family, member 3 [Homo sapiens]
Length = 502
Score = 37.4 bits (85), Expect = 0.14
Identities = 33/116 (28%), Positives = 41/116 (35%), Gaps = 24/116 (20%)
Query: 1224 ADSCALLVNLLQYVMSTGDLHPPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDL 1283
AD L +++Y +G PPP PP P + Q SP +P PP +
Sbjct: 325 ADYGMLPAQIIEYYNPSG---PPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASA------ 375
Query: 1284 ADALLDTERSLRELAQPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGS 1339
+ PS G L A P G PPP P GP SL S
Sbjct: 376 ------SSTHAAPPHPPSTGLLVTAPP---------PPGPPPPPPGPPGPGSSLSS 416
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 37.0 bits (84), Expect = 0.19
Identities = 32/127 (25%), Positives = 47/127 (37%), Gaps = 11/127 (8%)
Query: 1237 VMSTGDLHPPPRPPSP-TEIAGQKLSESPASLPSCPPVETALINQRDLADALLDTERSLR 1295
++ G HP P P SP +E QK + L P + + +D A + E+ +
Sbjct: 1246 ILPPGHSHPDPTPQSPDSETEDQKPTVKELELQEGPEENSTPLTTQDKAQVRIKQEQ-ME 1304
Query: 1296 ELAQPSGGHLPQAS---------PISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKED 1346
E A+ G PQ S P + P G P +P P GS C
Sbjct: 1305 EDAEEEAGSQPQDSGELDKGQGPPKEEHPDPPGNDGLPKVAPGPLLPGGSTPDCPSLHPQ 1364
Query: 1347 EREEEGD 1353
+ E G+
Sbjct: 1365 QESEAGE 1371
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 37.0 bits (84), Expect = 0.19
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 7/96 (7%)
Query: 1245 PPPRPPSPTEIAGQKLSESPAS---LPSCPPVETALINQRDLADALLDTERSLRELA--- 1298
PPP PP P +++ SP S P PP +A D A +T ++RELA
Sbjct: 221 PPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTL 280
Query: 1299 QPSGGHLPQASPISVYLFPGER-SGAPPPSPPVGGP 1333
+ L +A + L PG PPP PP P
Sbjct: 281 RQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPP 316
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 36.6 bits (83), Expect = 0.24
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 7/119 (5%)
Query: 1234 LQYVMSTGDLHPPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDLADALLDTERS 1293
LQ DL PP PT A + E P+ L + E + L D S
Sbjct: 391 LQGAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQLFTLGASEHS-----PLKTPYFDAGAS 445
Query: 1294 LRELAQPSGGHLPQASPISVYLFPGERS-GAPPPSPPVGGPAGSLGSCSEEKEDEREEE 1351
E P LP S L PG S G+P P PP G PA S E E+ EEE
Sbjct: 446 CTEQEMPRYHELPTLEERSGPLHPGATSLGSPIPVPP-GPPAVEDVSLDLEDEEGEEEE 503
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 36.6 bits (83), Expect = 0.24
Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 17/110 (15%)
Query: 1244 HPPPRPPSPTEI-----AGQKLSESPASLPSCPPVETALINQRDLADALLDTERSL---- 1294
HPPP P E+ + + +E P P+ PP ++DL+ A
Sbjct: 738 HPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSV 797
Query: 1295 --RELAQPSGG----HLPQASPISVYLFPGERSGAP--PPSPPVGGPAGS 1336
E A PSG P AS S + G+P PP+PP PA S
Sbjct: 798 ASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASS 847
>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
Length = 659
Score = 36.6 bits (83), Expect = 0.24
Identities = 37/123 (30%), Positives = 52/123 (42%), Gaps = 25/123 (20%)
Query: 1245 PPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDLADALLDTERS------LRELA 1298
PPP PP P G +L + L+ +R A L D + LR A
Sbjct: 26 PPPPPPLPPPSGGPELEG-----------DGLLLRERLAALGLDDPSPAEPGAPALRAPA 74
Query: 1299 QPSGGHLPQASPISVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKEDEREEEGDGDTLD 1358
+ G +A+ +S P ER APP P G P + E++E+ E E DGD L+
Sbjct: 75 AAAQGQARRAAELS----PEER--APPGRP--GAPEAAELELEEDEEEGEEAELDGDLLE 126
Query: 1359 SDE 1361
+E
Sbjct: 127 EEE 129
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 36.2 bits (82), Expect = 0.32
Identities = 54/184 (29%), Positives = 72/184 (39%), Gaps = 42/184 (22%)
Query: 606 LLRLATVPAEPP--------AGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPD 657
LL +AT P PP + +P+P E +TV ++ PRA L P+ +RP P
Sbjct: 974 LLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLG---PV-PVRPPPG 1029
Query: 658 PWAGQAVRAEQLRLELSEPQFRSELSSGPGPPV-PTHLELTCSDLHGIYEDGGKPPVPCL 716
P ELS ++ + GP P V P L ++ S +PP P L
Sbjct: 1030 P-------------ELS-----AQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVL 1071
Query: 717 RVSKALDPKSTGRKYFLPQVVVTVNPQSSSTQWEVAPEKGEELELSVESPCELR-EPEPS 775
L P S LPQV+ + S T P L L P +R P P
Sbjct: 1072 --LPPLQPNSGS----LPQVLPSPLGVLSGTSRPPTP----TLSLKPTPPAPVRLSPAPP 1121
Query: 776 PFSS 779
P SS
Sbjct: 1122 PGSS 1125
>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
Length = 616
Score = 35.8 bits (81), Expect = 0.42
Identities = 33/109 (30%), Positives = 38/109 (34%), Gaps = 16/109 (14%)
Query: 1241 GDLHPPPRPPSPTEIAGQKLSESPASLPSCPPVETALINQRDLADALLDTERSLRELAQP 1300
G P P PPS E + + S PS TA A A + P
Sbjct: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATA---------SGP 439
Query: 1301 SGGHLPQASPISVYLFPGERSGAPPPSP------PVGGPAGSLGSCSEE 1343
G P+A P + FP G P P P PV PAG G EE
Sbjct: 440 GSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPV-PPAGFAGLTPEE 487
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,316,672
Number of Sequences: 37866
Number of extensions: 4766377
Number of successful extensions: 23067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 184
Number of HSP's that attempted gapping in prelim test: 21794
Number of HSP's gapped (non-prelim): 1375
length of query: 1938
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1821
effective length of database: 13,817,196
effective search space: 25161113916
effective search space used: 25161113916
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.