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Search of human proteins with 238859658
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238859658 LIM and senescent cell antigen-like domains 2
isoform 1 [Homo sapiens]
(363 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 796 0.0
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 743 0.0
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 742 0.0
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 739 0.0
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 639 0.0
gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo ... 320 2e-87
gi|239758027 PREDICTED: similar to LIM and senescent cell antige... 180 2e-45
gi|170932518 paxillin isoform 3 [Homo sapiens] 145 7e-35
gi|170932516 paxillin isoform 2 [Homo sapiens] 145 7e-35
gi|170932514 paxillin isoform 1 [Homo sapiens] 145 7e-35
gi|221316659 leupaxin isoform 1 [Homo sapiens] 136 3e-32
gi|4758670 leupaxin isoform 2 [Homo sapiens] 136 3e-32
gi|109638745 transforming growth factor beta 1 induced transcrip... 136 3e-32
gi|21361591 transforming growth factor beta 1 induced transcript... 136 3e-32
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 131 1e-30
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 131 1e-30
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 131 1e-30
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 131 1e-30
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 119 6e-27
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 119 6e-27
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 119 6e-27
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 119 6e-27
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 119 6e-27
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 117 2e-26
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 117 2e-26
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 117 2e-26
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 117 2e-26
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 115 8e-26
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 114 1e-25
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 114 1e-25
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 796 bits (2056), Expect = 0.0
Identities = 363/363 (100%), Positives = 363/363 (100%)
Query: 1 MTGRKRKWGETGTGSGAAPAAALRWSNMSDALANAVCQRCQARFSPAERIVNSNGELYHE 60
MTGRKRKWGETGTGSGAAPAAALRWSNMSDALANAVCQRCQARFSPAERIVNSNGELYHE
Sbjct: 1 MTGRKRKWGETGTGSGAAPAAALRWSNMSDALANAVCQRCQARFSPAERIVNSNGELYHE 60
Query: 61 HCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPG 120
HCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPG
Sbjct: 61 HCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPG 120
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDA 180
CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDA
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDA 180
Query: 181 YHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWH 240
YHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWH
Sbjct: 181 YHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWH 240
Query: 241 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCV 300
VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCV
Sbjct: 241 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCV 300
Query: 301 SCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKATDL 360
SCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKATDL
Sbjct: 301 SCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKATDL 360
Query: 361 NSA 363
NSA
Sbjct: 361 NSA 363
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 743 bits (1919), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 26 SNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKY 85
SNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKY
Sbjct: 4 SNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKY 63
Query: 86 CEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC 145
CEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC
Sbjct: 64 CEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC 123
Query: 146 RPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE 205
RPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE
Sbjct: 124 RPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE 183
Query: 206 LYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLA 265
LYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLA
Sbjct: 184 LYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLA 243
Query: 266 YCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKP 325
YCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKP
Sbjct: 244 YCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKP 303
Query: 326 VCKRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA 363
VCKRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA
Sbjct: 304 VCKRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA 341
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 742 bits (1915), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 27 NMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYC 86
NMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYC
Sbjct: 29 NMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYC 88
Query: 87 EHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 146
EHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR
Sbjct: 89 EHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 148
Query: 147 PCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL 206
PCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL
Sbjct: 149 PCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL 208
Query: 207 YCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAY 266
YCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAY
Sbjct: 209 YCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAY 268
Query: 267 CETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 326
CETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV
Sbjct: 269 CETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 328
Query: 327 CKRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA 363
CKRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA
Sbjct: 329 CKRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA 365
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 739 bits (1909), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 28 MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87
MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE
Sbjct: 1 MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 60
Query: 88 HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP
Sbjct: 61 HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 120
Query: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELY 207
CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELY
Sbjct: 121 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELY 180
Query: 208 CLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 267
CLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC
Sbjct: 181 CLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 240
Query: 268 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVC 327
ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVC
Sbjct: 241 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVC 300
Query: 328 KRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA 363
KRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA
Sbjct: 301 KRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA 336
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 639 bits (1648), Expect = 0.0
Identities = 278/325 (85%), Positives = 307/325 (94%)
Query: 28 MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87
M++ALA+A C+RC+ F+PAE+IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYCE
Sbjct: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
Query: 88 HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
HDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCRP
Sbjct: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
Query: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELY 207
CHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CGKELTA+ARELKGELY
Sbjct: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180
Query: 208 CLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 267
CLPCHDKMGVPICGACRRPIEGRVVNA+GKQWHVEHFVCAKCEKPFLGHRHYE+KGLAYC
Sbjct: 181 CLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
Query: 268 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVC 327
ETHYNQLFGDVC++C+ VIEGDVVSALNKAWCV+CF+CSTCN+KLTLKNKFVEFDMKPVC
Sbjct: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
Query: 328 KRCYEKFPLELKKRLKKLSELTSRK 352
K+CYEKFPLELKKRLKKL+E RK
Sbjct: 301 KKCYEKFPLELKKRLKKLAETLGRK 325
>gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo
sapiens]
Length = 248
Score = 320 bits (819), Expect = 2e-87
Identities = 135/168 (80%), Positives = 153/168 (91%)
Query: 27 NMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYC 86
NM++ALA+A C+RC+ F+PAE IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYC
Sbjct: 62 NMANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYC 121
Query: 87 EHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 146
EHDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCR
Sbjct: 122 EHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 181
Query: 147 PCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 194
PCHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CG+E
Sbjct: 182 PCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229
Score = 74.7 bits (182), Expect = 1e-13
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
Query: 231 VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV 290
+VN+ G+ +H + FVCA+C + F YE +G YCE + LF C+ C I G V
Sbjct: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144
Query: 291 VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+ A+N +W CF C C L FV+ + +C+ C+ +
Sbjct: 145 IKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 186
Score = 59.7 bits (143), Expect = 4e-09
Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 8/166 (4%)
Query: 154 AKGLGKYICQRCH--LVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLP 210
A L C+RC E + + YH F C C ++ E +G YC
Sbjct: 64 ANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEH 123
Query: 211 CHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 270
+ P C C I GRV+ A+ WH E F C C++ + G C
Sbjct: 124 DFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183
Query: 271 YNQ-----LFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSK 311
+N+ L +C C +I+ + N + F+C+ C +
Sbjct: 184 HNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229
Score = 34.3 bits (77), Expect = 0.18
Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 5/90 (5%)
Query: 49 RIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE--HDFQM---LFAPCCGSCGE 103
R++ + +H CF C C + F + GR C H+ + L C C
Sbjct: 143 RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 202
Query: 104 FIIGRVIKAMNNNWHPGCFRCELCDVELAD 133
I + + N+ +HP F C C E +D
Sbjct: 203 IIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232
>gi|239758027 PREDICTED: similar to LIM and senescent cell
antigen-like domains 1 [Homo sapiens]
Length = 116
Score = 180 bits (456), Expect = 2e-45
Identities = 74/91 (81%), Positives = 84/91 (92%)
Query: 102 GEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYI 161
GEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCRPCHNREKA+GLGKYI
Sbjct: 26 GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85
Query: 162 CQRCHLVIDEQPLMFRSDAYHPDHFNCTHCG 192
CQ+CH +IDEQPL+F++D YHPDHFNC +CG
Sbjct: 86 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
Score = 45.8 bits (107), Expect = 6e-05
Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 16/110 (14%)
Query: 147 PCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK--G 204
P ++ K LG++I R + ++++HP+ F C C +E+ A+ +K G
Sbjct: 15 PLPGFQRLKKLGEFIIGRV--------IKAMNNSWHPECFRCDLC-QEVLADIGFVKNAG 65
Query: 205 ELYCLPCHDK-----MGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKC 249
C PCH++ +G IC C I+ + + +H +HF CA C
Sbjct: 66 RHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 115
Score = 38.9 bits (89), Expect = 0.007
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 5/87 (5%)
Query: 227 IEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQ-----LFGDVCYN 281
I GRV+ A+ WH E F C C++ + G C +N+ L +C
Sbjct: 29 IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
Query: 282 CSHVIEGDVVSALNKAWCVSCFSCSTC 308
C +I+ + N + F+C+ C
Sbjct: 89 CHAIIDEQPLIFKNDPYHPDHFNCANC 115
Score = 32.3 bits (72), Expect = 0.68
Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 286 IEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
I G V+ A+N +W CF C C L FV+ + +C+ C+ +
Sbjct: 29 IIGRVIKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 75
Score = 32.3 bits (72), Expect = 0.68
Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 5/84 (5%)
Query: 49 RIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE--HDFQM---LFAPCCGSCGE 103
R++ + +H CF C C + F + GR C H+ + L C C
Sbjct: 32 RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
Query: 104 FIIGRVIKAMNNNWHPGCFRCELC 127
I + + N+ +HP F C C
Sbjct: 92 IIDEQPLIFKNDPYHPDHFNCANC 115
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 145 bits (365), Expect = 7e-35
Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 156
CG+C + I G+V+ AM WHP F C C E+ F + G+ C + HN +
Sbjct: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 249
Query: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 215
C C+ I ++ + +HP+HF C CG E E G+ YC + M
Sbjct: 250 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 304
Query: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
P CG C R I ++AL WH E FVC +C PF+ +E G YCE HY++
Sbjct: 305 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
Query: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
G +C C I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 365 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 421
Score = 130 bits (326), Expect = 2e-30
Identities = 84/283 (29%), Positives = 128/283 (45%), Gaps = 24/283 (8%)
Query: 9 GETGTGS--GAAPAAALRWSNMSDAL------------ANAVCQRCQARFSPAERIVNSN 54
G+TG+ S G P + +M +L A VC C+ A ++V +
Sbjct: 149 GKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPI--AGQVVTAM 206
Query: 55 GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 114
G+ +H FVC C F+E +G+ YCE D+ LF+P C C I+ +V+ A++
Sbjct: 207 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 266
Query: 115 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 174
WHP F C C GF + G+ CR + A C C I E +
Sbjct: 267 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGGCARAILENYI 321
Query: 175 MFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-LPCHDKMGVPICGACRRPIEGRVV 232
+ +HP+ F C C + E G+ YC + H++ G +C C++PI GR +
Sbjct: 322 SALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG-SLCSGCQKPITGRCI 380
Query: 233 NALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
A+ K++H EHFVCA C K E+ YC+ + +LF
Sbjct: 381 TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
Score = 118 bits (295), Expect = 9e-27
Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 215
+ K +C C I Q + +HP+HF CTHC +E+ + E G+ YC + +
Sbjct: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
Query: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
P C C PI +VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 246 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 305
Query: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
C C+ I + +SALN W CF C C + + F E D +P C+ Y +
Sbjct: 306 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 362
Score = 101 bits (251), Expect = 1e-21
Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)
Query: 192 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 246
G +L + L+ +L +K+GV +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 164 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 217
Query: 247 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 306
C++ +E+ G YCE Y+ LF CY C+ I VV+AL++ W F C+
Sbjct: 218 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 277
Query: 307 TCNSKLTLKNKFVEFDMKPVCKRCY 331
C + + F E D K C++ Y
Sbjct: 278 QCGAFFGPEG-FHEKDGKAYCRKDY 301
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 145 bits (365), Expect = 7e-35
Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 156
CG+C + I G+V+ AM WHP F C C E+ F + G+ C + HN +
Sbjct: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 382
Query: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 215
C C+ I ++ + +HP+HF C CG E E G+ YC + M
Sbjct: 383 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 437
Query: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
P CG C R I ++AL WH E FVC +C PF+ +E G YCE HY++
Sbjct: 438 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
Query: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
G +C C I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 498 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 554
Score = 130 bits (326), Expect = 2e-30
Identities = 84/283 (29%), Positives = 128/283 (45%), Gaps = 24/283 (8%)
Query: 9 GETGTGS--GAAPAAALRWSNMSDAL------------ANAVCQRCQARFSPAERIVNSN 54
G+TG+ S G P + +M +L A VC C+ A ++V +
Sbjct: 282 GKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPI--AGQVVTAM 339
Query: 55 GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 114
G+ +H FVC C F+E +G+ YCE D+ LF+P C C I+ +V+ A++
Sbjct: 340 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 399
Query: 115 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 174
WHP F C C GF + G+ CR + A C C I E +
Sbjct: 400 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGGCARAILENYI 454
Query: 175 MFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-LPCHDKMGVPICGACRRPIEGRVV 232
+ +HP+ F C C + E G+ YC + H++ G +C C++PI GR +
Sbjct: 455 SALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG-SLCSGCQKPITGRCI 513
Query: 233 NALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
A+ K++H EHFVCA C K E+ YC+ + +LF
Sbjct: 514 TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
Score = 118 bits (295), Expect = 9e-27
Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 215
+ K +C C I Q + +HP+HF CTHC +E+ + E G+ YC + +
Sbjct: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
Query: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
P C C PI +VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 379 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 438
Query: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
C C+ I + +SALN W CF C C + + F E D +P C+ Y +
Sbjct: 439 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 495
Score = 101 bits (251), Expect = 1e-21
Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)
Query: 192 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 246
G +L + L+ +L +K+GV +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 297 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 350
Query: 247 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 306
C++ +E+ G YCE Y+ LF CY C+ I VV+AL++ W F C+
Sbjct: 351 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 410
Query: 307 TCNSKLTLKNKFVEFDMKPVCKRCY 331
C + + F E D K C++ Y
Sbjct: 411 QCGAFFGPEG-FHEKDGKAYCRKDY 434
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 145 bits (365), Expect = 7e-35
Identities = 79/238 (33%), Positives = 113/238 (47%), Gaps = 9/238 (3%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLC-RPCHNREKAKG 156
CG+C + I G+V+ AM WHP F C C E+ F + G+ C + HN +
Sbjct: 358 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 416
Query: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKM 215
C C+ I ++ + +HP+HF C CG E E G+ YC + M
Sbjct: 417 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 471
Query: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
P CG C R I ++AL WH E FVC +C PF+ +E G YCE HY++
Sbjct: 472 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 531
Query: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
G +C C I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 532 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 588
Score = 130 bits (326), Expect = 2e-30
Identities = 84/283 (29%), Positives = 128/283 (45%), Gaps = 24/283 (8%)
Query: 9 GETGTGS--GAAPAAALRWSNMSDAL------------ANAVCQRCQARFSPAERIVNSN 54
G+TG+ S G P + +M +L A VC C+ A ++V +
Sbjct: 316 GKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPI--AGQVVTAM 373
Query: 55 GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 114
G+ +H FVC C F+E +G+ YCE D+ LF+P C C I+ +V+ A++
Sbjct: 374 GKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALD 433
Query: 115 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 174
WHP F C C GF + G+ CR + A C C I E +
Sbjct: 434 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK-----CGGCARAILENYI 488
Query: 175 MFRSDAYHPDHFNCTHCGKE-LTAEARELKGELYC-LPCHDKMGVPICGACRRPIEGRVV 232
+ +HP+ F C C + E G+ YC + H++ G +C C++PI GR +
Sbjct: 489 SALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRG-SLCSGCQKPITGRCI 547
Query: 233 NALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
A+ K++H EHFVCA C K E+ YC+ + +LF
Sbjct: 548 TAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
Score = 118 bits (295), Expect = 9e-27
Identities = 62/178 (34%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYCLPCHDKM 215
+ K +C C I Q + +HP+HF CTHC +E+ + E G+ YC + +
Sbjct: 353 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 412
Query: 216 GVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 275
P C C PI +VV AL + WH EHF CA+C F +EK G AYC Y +F
Sbjct: 413 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 472
Query: 276 GDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
C C+ I + +SALN W CF C C + + F E D +P C+ Y +
Sbjct: 473 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 529
Score = 101 bits (251), Expect = 1e-21
Identities = 53/145 (36%), Positives = 78/145 (53%), Gaps = 12/145 (8%)
Query: 192 GKELTAEARELKGELYCLPCHDKMGVP-----ICGACRRPIEGRVVNALGKQWHVEHFVC 246
G +L + L+ +L +K+GV +CGAC++PI G+VV A+GK WH EHFVC
Sbjct: 331 GSQLDSMLGSLQSDL------NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVC 384
Query: 247 AKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 306
C++ +E+ G YCE Y+ LF CY C+ I VV+AL++ W F C+
Sbjct: 385 THCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCA 444
Query: 307 TCNSKLTLKNKFVEFDMKPVCKRCY 331
C + + F E D K C++ Y
Sbjct: 445 QCGAFFGPEG-FHEKDGKAYCRKDY 468
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 136 bits (343), Expect = 3e-32
Identities = 79/241 (32%), Positives = 116/241 (48%), Gaps = 8/241 (3%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157
C SC + I G+VI A+ +WHP F C C E+ F + +G C +++ L
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 211
Query: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 216
C C I ++ L + +HP+HF C+HCG+ AE E + YC M
Sbjct: 212 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271
Query: 217 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 276
P CG C RP+ ++A+ WH E FVC C F +E G +CE HY+ G
Sbjct: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
Query: 277 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK-FP 335
+C+ C I G +SA+ + F C+ C ++L+ K F E + K C+ C+ K FP
Sbjct: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 390
Query: 336 L 336
L
Sbjct: 391 L 391
Score = 128 bits (321), Expect = 9e-30
Identities = 75/241 (31%), Positives = 110/241 (45%), Gaps = 10/241 (4%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C CQ A +++++ G+ +H FVC C F+E G YC +D+ LF+P
Sbjct: 157 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
Query: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
C C I+ +V+ AMN WHP F C C GF + + C R+
Sbjct: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLA 269
Query: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYC-LPCHDK 214
+ C C+ + E L +HP+ F C C T EL G +C L H +
Sbjct: 270 MFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHR 329
Query: 215 MGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQL 274
G +C C +PI GR ++A+G ++H EHFVCA C E+ YC+ +N+L
Sbjct: 330 RGT-LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 388
Query: 275 F 275
F
Sbjct: 389 F 389
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 136 bits (343), Expect = 3e-32
Identities = 79/241 (32%), Positives = 116/241 (48%), Gaps = 8/241 (3%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157
C SC + I G+VI A+ +WHP F C C E+ F + +G C +++ L
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 206
Query: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 216
C C I ++ L + +HP+HF C+HCG+ AE E + YC M
Sbjct: 207 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 266
Query: 217 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 276
P CG C RP+ ++A+ WH E FVC C F +E G +CE HY+ G
Sbjct: 267 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 326
Query: 277 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK-FP 335
+C+ C I G +SA+ + F C+ C ++L+ K F E + K C+ C+ K FP
Sbjct: 327 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 385
Query: 336 L 336
L
Sbjct: 386 L 386
Score = 128 bits (321), Expect = 9e-30
Identities = 75/241 (31%), Positives = 110/241 (45%), Gaps = 10/241 (4%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C CQ A +++++ G+ +H FVC C F+E G YC +D+ LF+P
Sbjct: 152 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209
Query: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
C C I+ +V+ AMN WHP F C C GF + + C R+
Sbjct: 210 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLA 264
Query: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYC-LPCHDK 214
+ C C+ + E L +HP+ F C C T EL G +C L H +
Sbjct: 265 MFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHR 324
Query: 215 MGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQL 274
G +C C +PI GR ++A+G ++H EHFVCA C E+ YC+ +N+L
Sbjct: 325 RGT-LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 383
Query: 275 F 275
F
Sbjct: 384 F 384
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 136 bits (343), Expect = 3e-32
Identities = 76/237 (32%), Positives = 109/237 (45%), Gaps = 7/237 (2%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157
CGSC + I G+V+ A+ WHP F C C L F + G C C+ +
Sbjct: 228 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 286
Query: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 216
C C+ I + + +HP+HF C CG+ E E +G YC ++
Sbjct: 287 ----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLF 342
Query: 217 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 276
P C C+ PI ++AL WH + FVC +C PF G +E +G CE H++ G
Sbjct: 343 APRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRG 402
Query: 277 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+C C + G VSAL + + F+C+ C LT K F E KP C+ C+ K
Sbjct: 403 SLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 458
Score = 120 bits (302), Expect = 1e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 33 ANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQM 92
A +C C A ++V + G +H FVC C F+E +G +C +
Sbjct: 224 AKGLCGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 281
Query: 93 LFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNRE 152
F+P CG C + I +++ A+ +WHP F C C D GF + GR C R
Sbjct: 282 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 336
Query: 153 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPC 211
L CQ C I + + S +HPD F C C + + E +G C
Sbjct: 337 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 396
Query: 212 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 271
+C C P+ GR V+ALG+++H +HF C C +P E+ G YC+ +
Sbjct: 397 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 456
Query: 272 NQLFG 276
+LFG
Sbjct: 457 LKLFG 461
Score = 115 bits (288), Expect = 6e-26
Identities = 61/177 (34%), Positives = 87/177 (49%), Gaps = 6/177 (3%)
Query: 153 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPC 211
+AKGL C C+ I Q + A+HP+HF C C L + E G +C C
Sbjct: 223 QAKGL----CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 278
Query: 212 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 271
+ + P CG C +PI ++V ALG WH EHF C C +PF +E++G YC +
Sbjct: 279 YFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDF 338
Query: 272 NQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 328
QLF C C I + +SAL+ W CF C C + + F E + +P+C+
Sbjct: 339 LQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 394
Score = 114 bits (284), Expect = 2e-25
Identities = 67/207 (32%), Positives = 93/207 (44%), Gaps = 16/207 (7%)
Query: 20 AAALRWSNMSDALANAVCQRCQ-ARFSPA---------ERIVNSNGELYHEHCFVCAQCF 69
+ AL S+ + C C RFSP ++V + G +H F C C
Sbjct: 258 STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG 317
Query: 70 RPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDV 129
PF + F+E EGR YC DF LFAP C C I+ I A++ WHP CF C C
Sbjct: 318 EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA 377
Query: 130 ELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCT 189
+ F ++ GR LC + + +C C L + + + +HPDHF CT
Sbjct: 378 PFSGGSFFEHEGRPLCENHFHARRGS-----LCATCGLPVTGRCVSALGRRFHPDHFTCT 432
Query: 190 HCGKELT-AEARELKGELYCLPCHDKM 215
C + LT +E G+ YC PC K+
Sbjct: 433 FCLRPLTKGSFQERAGKPYCQPCFLKL 459
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 136 bits (343), Expect = 3e-32
Identities = 76/237 (32%), Positives = 109/237 (45%), Gaps = 7/237 (2%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157
CGSC + I G+V+ A+ WHP F C C L F + G C C+ +
Sbjct: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 269
Query: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 216
C C+ I + + +HP+HF C CG+ E E +G YC ++
Sbjct: 270 ----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLF 325
Query: 217 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 276
P C C+ PI ++AL WH + FVC +C PF G +E +G CE H++ G
Sbjct: 326 APRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRG 385
Query: 277 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+C C + G VSAL + + F+C+ C LT K F E KP C+ C+ K
Sbjct: 386 SLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 441
Score = 120 bits (302), Expect = 1e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 33 ANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQM 92
A +C C A ++V + G +H FVC C F+E +G +C +
Sbjct: 207 AKGLCGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 264
Query: 93 LFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNRE 152
F+P CG C + I +++ A+ +WHP F C C D GF + GR C R
Sbjct: 265 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 319
Query: 153 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPC 211
L CQ C I + + S +HPD F C C + + E +G C
Sbjct: 320 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 379
Query: 212 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 271
+C C P+ GR V+ALG+++H +HF C C +P E+ G YC+ +
Sbjct: 380 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
Query: 272 NQLFG 276
+LFG
Sbjct: 440 LKLFG 444
Score = 115 bits (288), Expect = 6e-26
Identities = 61/177 (34%), Positives = 87/177 (49%), Gaps = 6/177 (3%)
Query: 153 KAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPC 211
+AKGL C C+ I Q + A+HP+HF C C L + E G +C C
Sbjct: 206 QAKGL----CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 261
Query: 212 HDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHY 271
+ + P CG C +PI ++V ALG WH EHF C C +PF +E++G YC +
Sbjct: 262 YFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDF 321
Query: 272 NQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 328
QLF C C I + +SAL+ W CF C C + + F E + +P+C+
Sbjct: 322 LQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 377
Score = 114 bits (284), Expect = 2e-25
Identities = 67/207 (32%), Positives = 93/207 (44%), Gaps = 16/207 (7%)
Query: 20 AAALRWSNMSDALANAVCQRCQ-ARFSPA---------ERIVNSNGELYHEHCFVCAQCF 69
+ AL S+ + C C RFSP ++V + G +H F C C
Sbjct: 241 STALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCG 300
Query: 70 RPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDV 129
PF + F+E EGR YC DF LFAP C C I+ I A++ WHP CF C C
Sbjct: 301 EPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFA 360
Query: 130 ELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCT 189
+ F ++ GR LC + + +C C L + + + +HPDHF CT
Sbjct: 361 PFSGGSFFEHEGRPLCENHFHARRGS-----LCATCGLPVTGRCVSALGRRFHPDHFTCT 415
Query: 190 HCGKELT-AEARELKGELYCLPCHDKM 215
C + LT +E G+ YC PC K+
Sbjct: 416 FCLRPLTKGSFQERAGKPYCQPCFLKL 442
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 131 bits (329), Expect = 1e-30
Identities = 69/172 (40%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
Query: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 219
+C C+ VI L+ ++HP+ FNC HC + E KG LYC C++K P
Sbjct: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
Query: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 279
CG C+R I G V++AL + WHV FVC C KP + + + G YCET Y LFG +C
Sbjct: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
Query: 280 YNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKR 329
+ C IE GD+ + AL W +CF CS C L + F + D KP+CK+
Sbjct: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 480
Score = 91.7 bits (226), Expect = 9e-19
Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 8/178 (4%)
Query: 96 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
P C C + I G + A+ +WHP F C C +A +GFV+ G C C+ + A
Sbjct: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
Query: 156 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDK 214
C RC I + + +H F C CGK + L+ GE YC +
Sbjct: 369 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 423
Query: 215 MGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 270
+ IC C PIE + ALG WH FVC+ C + G + KK C+ H
Sbjct: 424 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 481
Score = 90.9 bits (224), Expect = 2e-18
Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 218 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 277
P+C C + I G + ALGK WH E F CA C+ E+KG YCE Y + F
Sbjct: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
Query: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 331
C C I G+V+SAL + W VSCF C C + N F D +P C+ Y
Sbjct: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIR-NNVFHLEDGEPYCETDY 421
Score = 70.1 bits (170), Expect = 3e-12
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 6/113 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C RCQ + ++++ + +H CFVC C +P +F+ +G YCE D+ LF
Sbjct: 370 CGRCQRKI--LGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
Query: 97 CCGSCGEFII---GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 146
C C EF I ++A+ WH CF C +C L F + LC+
Sbjct: 428 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
Score = 69.7 bits (169), Expect = 4e-12
Identities = 43/146 (29%), Positives = 59/146 (40%), Gaps = 7/146 (4%)
Query: 55 GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 114
G+ +H F CA C F E +G YCE ++ FAP CG C I+G VI A+
Sbjct: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
Query: 115 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 174
WH CF C C + + F G C + L IC C I+ +
Sbjct: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 441
Query: 175 MFRSDAY--HPDHFNCTHCGKELTAE 198
+ Y H F C+ C + L +
Sbjct: 442 FLEALGYTWHDTCFVCSVCCESLEGQ 467
Score = 42.7 bits (99), Expect = 5e-04
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF 334
+C +C+ VI G + AL K+W F+C+ C + + FVE C+ CYEKF
Sbjct: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 365
Score = 34.7 bits (78), Expect = 0.14
Identities = 13/57 (22%), Positives = 25/57 (43%)
Query: 31 ALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87
AL +C C+ + + + G +H+ CFVC+ C F+ + + C+
Sbjct: 423 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 131 bits (329), Expect = 1e-30
Identities = 69/172 (40%), Positives = 94/172 (54%), Gaps = 4/172 (2%)
Query: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 219
+C C+ VI L+ ++HP+ FNC HC + E KG LYC C++K P
Sbjct: 419 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 478
Query: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 279
CG C+R I G V++AL + WHV FVC C KP + + + G YCET Y LFG +C
Sbjct: 479 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 538
Query: 280 YNCSHVIE-GDV-VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKR 329
+ C IE GD+ + AL W +CF CS C L + F + D KP+CK+
Sbjct: 539 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 589
Score = 91.7 bits (226), Expect = 9e-19
Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 8/178 (4%)
Query: 96 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
P C C + I G + A+ +WHP F C C +A +GFV+ G C C+ + A
Sbjct: 418 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477
Query: 156 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDK 214
C RC I + + +H F C CGK + L+ GE YC +
Sbjct: 478 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 532
Query: 215 MGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 270
+ IC C PIE + ALG WH FVC+ C + G + KK C+ H
Sbjct: 533 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 590
Score = 90.9 bits (224), Expect = 2e-18
Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 218 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 277
P+C C + I G + ALGK WH E F CA C+ E+KG YCE Y + F
Sbjct: 418 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477
Query: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 331
C C I G+V+SAL + W VSCF C C + N F D +P C+ Y
Sbjct: 478 ECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIR-NNVFHLEDGEPYCETDY 530
Score = 70.1 bits (170), Expect = 3e-12
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 6/113 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C RCQ + ++++ + +H CFVC C +P +F+ +G YCE D+ LF
Sbjct: 479 CGRCQRKI--LGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 536
Query: 97 CCGSCGEFII---GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCR 146
C C EF I ++A+ WH CF C +C L F + LC+
Sbjct: 537 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588
Score = 69.7 bits (169), Expect = 4e-12
Identities = 43/146 (29%), Positives = 59/146 (40%), Gaps = 7/146 (4%)
Query: 55 GELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMN 114
G+ +H F CA C F E +G YCE ++ FAP CG C I+G VI A+
Sbjct: 436 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 495
Query: 115 NNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPL 174
WH CF C C + + F G C + L IC C I+ +
Sbjct: 496 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 550
Query: 175 MFRSDAY--HPDHFNCTHCGKELTAE 198
+ Y H F C+ C + L +
Sbjct: 551 FLEALGYTWHDTCFVCSVCCESLEGQ 576
Score = 42.7 bits (99), Expect = 5e-04
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF 334
+C +C+ VI G + AL K+W F+C+ C + + FVE C+ CYEKF
Sbjct: 419 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 474
Score = 34.7 bits (78), Expect = 0.14
Identities = 13/57 (22%), Positives = 25/57 (43%)
Query: 31 ALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87
AL +C C+ + + + G +H+ CFVC+ C F+ + + C+
Sbjct: 532 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 131 bits (329), Expect = 1e-30
Identities = 64/171 (37%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Query: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 219
+C +CH VI + L+ AYHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 247 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 306
Query: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 279
C C++ I G +++AL WHV F CA C+ P Y ++G+ YCE Y ++FG C
Sbjct: 307 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 366
Query: 280 YNCSHVIE-GD-VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 328
+ C I+ GD + AL +W +CF C+ C L K + + D +P+CK
Sbjct: 367 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 416
Score = 87.8 bits (216), Expect = 1e-17
Identities = 40/116 (34%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 218 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 277
P+C C + I GR + ALG +H E FVC++C K +E+KG +C Y+ +
Sbjct: 246 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
C C I G+++ AL W V CF+C+ C + + + ++E + P C+R YEK
Sbjct: 306 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 360
Score = 82.4 bits (202), Expect = 6e-16
Identities = 53/178 (29%), Positives = 76/178 (42%), Gaps = 8/178 (4%)
Query: 96 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
P C C + I GR + A+ + +HP F C C L + GF + G C PC++ A
Sbjct: 246 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 156 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL-KGELYCLPCHDK 214
C +C I + + +H F C C + A + +G YC ++K
Sbjct: 306 S-----CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEK 360
Query: 215 MGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 270
M C C I+ R + ALG WH FVCA C+ G Y KK C++H
Sbjct: 361 MFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 418
Score = 75.9 bits (185), Expect = 5e-14
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Query: 36 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 95
VC +C R + + G YH FVC+QC + EG F+E +G +C + + +A
Sbjct: 247 VCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304
Query: 96 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
P C C + I G ++ A+ WH CF C C + + F G C R+ K
Sbjct: 305 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYC----ERDYEK 360
Query: 156 GLGKYICQRCHLVID--EQPLMFRSDAYHPDHFNCTHC 191
G C C ID ++ L ++H F C C
Sbjct: 361 MFGTK-CHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC 397
Score = 35.0 bits (79), Expect = 0.10
Identities = 15/51 (29%), Positives = 23/51 (45%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87
C C + +R + + G +H+ CFVCA C FY + R C+
Sbjct: 366 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 416
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 131 bits (329), Expect = 1e-30
Identities = 64/171 (37%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Query: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 219
+C +CH VI + L+ AYHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
Query: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 279
C C++ I G +++AL WHV F CA C+ P Y ++G+ YCE Y ++FG C
Sbjct: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
Query: 280 YNCSHVIE-GD-VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 328
+ C I+ GD + AL +W +CF C+ C L K + + D +P+CK
Sbjct: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 450
Score = 87.8 bits (216), Expect = 1e-17
Identities = 40/116 (34%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 218 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 277
P+C C + I GR + ALG +H E FVC++C K +E+KG +C Y+ +
Sbjct: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
C C I G+++ AL W V CF+C+ C + + + ++E + P C+R YEK
Sbjct: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 394
Score = 82.4 bits (202), Expect = 6e-16
Identities = 53/178 (29%), Positives = 76/178 (42%), Gaps = 8/178 (4%)
Query: 96 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
P C C + I GR + A+ + +HP F C C L + GF + G C PC++ A
Sbjct: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 156 GLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL-KGELYCLPCHDK 214
C +C I + + +H F C C + A + +G YC ++K
Sbjct: 340 S-----CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEK 394
Query: 215 MGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETH 270
M C C I+ R + ALG WH FVCA C+ G Y KK C++H
Sbjct: 395 MFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
Score = 75.9 bits (185), Expect = 5e-14
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Query: 36 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 95
VC +C R + + G YH FVC+QC + EG F+E +G +C + + +A
Sbjct: 281 VCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
Query: 96 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
P C C + I G ++ A+ WH CF C C + + F G C R+ K
Sbjct: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYC----ERDYEK 394
Query: 156 GLGKYICQRCHLVID--EQPLMFRSDAYHPDHFNCTHC 191
G C C ID ++ L ++H F C C
Sbjct: 395 MFGTK-CHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC 431
Score = 35.0 bits (79), Expect = 0.10
Identities = 15/51 (29%), Positives = 23/51 (45%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87
C C + +R + + G +H+ CFVCA C FY + R C+
Sbjct: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 119 bits (297), Expect = 6e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C P + + +G C F A C C + I + + N WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 177
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
Query: 178 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 236
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 291
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 238
Query: 292 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 239 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 279
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 30 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 33 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
Query: 90 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
Query: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 206
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
Query: 207 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 261
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 208 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 267
Query: 262 KGLAYC 267
+ YC
Sbjct: 268 QEQVYC 273
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160
Query: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
Query: 157 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 210
C C I + + ++H F+C C L + E +YC
Sbjct: 221 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 211 CHDKM 215
C K+
Sbjct: 276 CAKKL 280
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 119 bits (297), Expect = 6e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C P + + +G C F A C C + I + + N WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 177
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
Query: 178 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 236
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 291
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 238
Query: 292 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 239 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 279
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 30 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 33 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
Query: 90 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
Query: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 206
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
Query: 207 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 261
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 208 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 267
Query: 262 KGLAYC 267
+ YC
Sbjct: 268 QEQVYC 273
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160
Query: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
Query: 157 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 210
C C I + + ++H F+C C L + E +YC
Sbjct: 221 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 211 CHDKM 215
C K+
Sbjct: 276 CAKKL 280
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 119 bits (297), Expect = 6e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C P + + +G C F A C C + I + + N WH
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 177
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 94 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 147
Query: 178 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 236
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 148 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 207
Query: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 291
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 208 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 267
Query: 292 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 268 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 308
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 30 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 62 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 121
Query: 90 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 122 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 181
Query: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 206
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 182 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 236
Query: 207 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 261
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 237 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 296
Query: 262 KGLAYC 267
+ YC
Sbjct: 297 QEQVYC 302
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 130 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 189
Query: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 190 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 249
Query: 157 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 210
C C I + + ++H F+C C L + E +YC
Sbjct: 250 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 304
Query: 211 CHDKM 215
C K+
Sbjct: 305 CAKKL 309
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 119 bits (297), Expect = 6e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C P + + +G C F A C C + I + + N WH
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 177
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 134
Query: 178 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 236
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
Query: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 291
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
Query: 292 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 255 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 295
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 30 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 49 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 108
Query: 90 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 109 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 168
Query: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 206
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 169 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 223
Query: 207 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 261
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 224 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 283
Query: 262 KGLAYC 267
+ YC
Sbjct: 284 QEQVYC 289
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 117 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 176
Query: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 236
Query: 157 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 210
C C I + + ++H F+C C L + E +YC
Sbjct: 237 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291
Query: 211 CHDKM 215
C K+
Sbjct: 292 CAKKL 296
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 119 bits (297), Expect = 6e-27
Identities = 80/282 (28%), Positives = 113/282 (40%), Gaps = 18/282 (6%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C P + + +G C F A C C + I + + N WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 177
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
Query: 178 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 236
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG-----DVV 291
+ WH + FVC C K G R + YC Y C C + I G VV
Sbjct: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 238
Query: 292 SALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 239 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 279
Score = 100 bits (249), Expect = 2e-21
Identities = 59/246 (23%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 30 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 33 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
Query: 90 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
Query: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 206
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
Query: 207 YCLPCHDKMGVPICGACRRPIEG-----RVVNALGKQWHVEHFVCAKCEKPFLGHRHYEK 261
YC+ C+ C C+ PI G VV G+ WH F C KC R
Sbjct: 208 YCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFH 267
Query: 262 KGLAYC 267
+ YC
Sbjct: 268 QEQVYC 273
Score = 67.8 bits (164), Expect = 1e-11
Identities = 45/185 (24%), Positives = 69/185 (37%), Gaps = 11/185 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C ++ V G ++H+ CF C+ C + G F+ YC + FA
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAK 160
Query: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
C C + I I + WH CF C C +LA F ++ C C+ AK
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
Query: 157 LGKYICQRCHLVI-----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLP 210
C C I + + ++H F+C C L + E +YC
Sbjct: 221 -----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
Query: 211 CHDKM 215
C K+
Sbjct: 276 CAKKL 280
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 117 bits (293), Expect = 2e-26
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C + E YC F+ LFA C CG+ I + + + +WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 178
CF C C L D F + LC C++ E + CQ C I + + ++
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
Query: 179 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 237
++H F C C + + ++ K + +C+PC++K C C++PI V +
Sbjct: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
Query: 238 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 293
WH E FVC C K G R + AYC + L+ C C++ I G +S
Sbjct: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
Query: 294 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 322
+ W CF+C C+ L + E D
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
Score = 98.2 bits (243), Expect = 1e-20
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C + ++ +HE CF C+QC + F E + C + ++
Sbjct: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
Query: 97 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154
C C + I+ R ++ ++WH CF C C + F+ ++ C PC+ ++ A
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Query: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 213
C +C I + +R +H + F CT C K+L+ + + + YCL C
Sbjct: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
Query: 214 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 255
+ C C PI G + ++ +QWH + F C KC +G
Sbjct: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
Score = 66.6 bits (161), Expect = 3e-11
Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)
Query: 184 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 240
+ F+C HC + L + L+ E YC+ C + + C C +PI + + ++ + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 241 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 298
F C++C + K+ C Y+ + C C I + +W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 299 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+CF C C + K+ F+ D + C CYEK
Sbjct: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
Score = 55.8 bits (133), Expect = 6e-08
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 58 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 113
+H+ CFVC C + F + YC + F L+A C C I G + I
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 114 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 148
WH CF C+ C + L GF+ LC C
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 48.9 bits (115), Expect = 7e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 242 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 299
E F C C + G ++ ++ YC + LF + C C I D +S ++ W
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 300 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 358
+CF CS C + L K F + + +C CY + KK +RK + K +
Sbjct: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 117 bits (293), Expect = 2e-26
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C + E YC F+ LFA C CG+ I + + + +WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 178
CF C C L D F + LC C++ E + CQ C I + + ++
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
Query: 179 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 237
++H F C C + + ++ K + +C+PC++K C C++PI V +
Sbjct: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
Query: 238 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 293
WH E FVC C K G R + AYC + L+ C C++ I G +S
Sbjct: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
Query: 294 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 322
+ W CF+C C+ L + E D
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
Score = 98.2 bits (243), Expect = 1e-20
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C + ++ +HE CF C+QC + F E + C + ++
Sbjct: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
Query: 97 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154
C C + I+ R ++ ++WH CF C C + F+ ++ C PC+ ++ A
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Query: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 213
C +C I + +R +H + F CT C K+L+ + + + YCL C
Sbjct: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
Query: 214 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 255
+ C C PI G + ++ +QWH + F C KC +G
Sbjct: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
Score = 66.6 bits (161), Expect = 3e-11
Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)
Query: 184 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 240
+ F+C HC + L + L+ E YC+ C + + C C +PI + + ++ + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 241 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 298
F C++C + K+ C Y+ + C C I + +W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 299 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+CF C C + K+ F+ D + C CYEK
Sbjct: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
Score = 55.8 bits (133), Expect = 6e-08
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 58 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 113
+H+ CFVC C + F + YC + F L+A C C I G + I
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 114 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 148
WH CF C+ C + L GF+ LC C
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 48.9 bits (115), Expect = 7e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 242 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 299
E F C C + G ++ ++ YC + LF + C C I D +S ++ W
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 300 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 358
+CF CS C + L K F + + +C CY + KK +RK + K +
Sbjct: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 117 bits (293), Expect = 2e-26
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C + E YC F+ LFA C CG+ I + + + +WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 178
CF C C L D F + LC C++ E + CQ C I + + ++
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
Query: 179 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 237
++H F C C + + ++ K + +C+PC++K C C++PI V +
Sbjct: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
Query: 238 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 293
WH E FVC C K G R + AYC + L+ C C++ I G +S
Sbjct: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
Query: 294 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 322
+ W CF+C C+ L + E D
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
Score = 98.2 bits (243), Expect = 1e-20
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C + ++ +HE CF C+QC + F E + C + ++
Sbjct: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
Query: 97 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154
C C + I+ R ++ ++WH CF C C + F+ ++ C PC+ ++ A
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Query: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 213
C +C I + +R +H + F CT C K+L+ + + + YCL C
Sbjct: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
Query: 214 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 255
+ C C PI G + ++ +QWH + F C KC +G
Sbjct: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
Score = 66.6 bits (161), Expect = 3e-11
Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)
Query: 184 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 240
+ F+C HC + L + L+ E YC+ C + + C C +PI + + ++ + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 241 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 298
F C++C + K+ C Y+ + C C I + +W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 299 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+CF C C + K+ F+ D + C CYEK
Sbjct: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
Score = 55.8 bits (133), Expect = 6e-08
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 58 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 113
+H+ CFVC C + F + YC + F L+A C C I G + I
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 114 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 148
WH CF C+ C + L GF+ LC C
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 48.9 bits (115), Expect = 7e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 242 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 299
E F C C + G ++ ++ YC + LF + C C I D +S ++ W
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 300 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 358
+CF CS C + L K F + + +C CY + KK +RK + K +
Sbjct: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 117 bits (293), Expect = 2e-26
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F C C + E YC F+ LFA C CG+ I + + + +WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 178
CF C C L D F + LC C++ E + CQ C I + + ++
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
Query: 179 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 237
++H F C C + + ++ K + +C+PC++K C C++PI V +
Sbjct: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
Query: 238 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 293
WH E FVC C K G R + AYC + L+ C C++ I G +S
Sbjct: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
Query: 294 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 322
+ W CF+C C+ L + E D
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
Score = 98.2 bits (243), Expect = 1e-20
Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C+ C + ++ +HE CF C+QC + F E + C + ++
Sbjct: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
Query: 97 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154
C C + I+ R ++ ++WH CF C C + F+ ++ C PC+ ++ A
Sbjct: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Query: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 213
C +C I + +R +H + F CT C K+L+ + + + YCL C
Sbjct: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
Query: 214 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 255
+ C C PI G + ++ +QWH + F C KC +G
Sbjct: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
Score = 66.6 bits (161), Expect = 3e-11
Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)
Query: 184 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 240
+ F+C HC + L + L+ E YC+ C + + C C +PI + + ++ + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 241 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 298
F C++C + K+ C Y+ + C C I + +W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 299 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
+CF C C + K+ F+ D + C CYEK
Sbjct: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
Score = 55.8 bits (133), Expect = 6e-08
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)
Query: 58 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 113
+H+ CFVC C + F + YC + F L+A C C I G + I
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 114 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 148
WH CF C+ C + L GF+ LC C
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 48.9 bits (115), Expect = 7e-06
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 242 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 299
E F C C + G ++ ++ YC + LF + C C I D +S ++ W
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 300 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 358
+CF CS C + L K F + + +C CY + KK +RK + K +
Sbjct: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 115 bits (287), Expect = 8e-26
Identities = 68/257 (26%), Positives = 107/257 (41%), Gaps = 20/257 (7%)
Query: 6 RKWGETGTGSGAAPAAALRWSNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVC 65
RK+ +T +G P ++N C CQ R + +HE CF C
Sbjct: 17 RKYIQTDSGPYCVPCYDNTFAN--------TCAECQQLIGHDSRELFYEDRHFHEGCFRC 68
Query: 66 AQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFII--GRVIKAMNNNWHPGCFR 123
+C R + F + C + F+ C +CGE ++ R ++ WH CF
Sbjct: 69 CRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFL 128
Query: 124 CELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHP 183
C C+ L FV + G H C PC+ + A C RC + + + +R +H
Sbjct: 129 CSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPR-----CARCSKTLTQGGVTYRDQPWHR 183
Query: 184 DHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPI----EGRVVNALGKQ 238
+ CT C L + + E YC+ C ++ P C +C+RPI G+ V+ +
Sbjct: 184 ECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRH 243
Query: 239 WHVEHFVCAKCEKPFLG 255
WH F CA+C +G
Sbjct: 244 WHHNCFSCARCSTSLVG 260
Score = 112 bits (281), Expect = 4e-25
Identities = 74/282 (26%), Positives = 117/282 (41%), Gaps = 15/282 (5%)
Query: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
F CA+C + + + YC + FA C C + I R + + ++H G
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 178
CFRC C LAD F LC C+ + C C + + L +
Sbjct: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQ-----CSACGETVMPGSRKLEYGG 119
Query: 179 DAYHPDHFNCTHCGKELTAEAREL-KGELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 237
+H F C+ C + L + + KG YC+PC++ P C C + + V +
Sbjct: 120 QTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQ 179
Query: 238 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVI----EGDVVSA 293
WH E VC C+ P G + + YC + +LF C +C I G VS
Sbjct: 180 PWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSF 239
Query: 294 LNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFP 335
++ W +CFSC+ C++ L + FV + +C+ C + P
Sbjct: 240 EDRHWHHNCFSCARCSTSL-VGQGFVPDGDQVLCQGCSQAGP 280
Score = 73.6 bits (179), Expect = 3e-13
Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 10/180 (5%)
Query: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96
C C P R + G+ +HEHCF+C+ C +P F +G YC ++ FAP
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
Query: 97 CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156
C C + + + + WH C C C LA F C C A
Sbjct: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
Query: 157 LGKYICQRCHLVI----DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKG-ELYCLPC 211
C C I + + F +H + F+C C L + G ++ C C
Sbjct: 221 -----CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
Score = 45.8 bits (107), Expect = 6e-05
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 242 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSAL--NKAWC 299
E F CAKC + G ++ + YC Y+ F + C C +I D ++ +
Sbjct: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
Query: 300 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 331
CF C C L F D + +C CY
Sbjct: 63 EGCFRCCRCQRSLA-DEPFTCQDSELLCNDCY 93
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 114 bits (285), Expect = 1e-25
Identities = 72/227 (31%), Positives = 97/227 (42%), Gaps = 17/227 (7%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157
C CGE G V++ ++H CF C++C +LA GF G +LC + R
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR- 97
Query: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLPC 211
C C ++ + + YHP+ F CT C G +T R+ +L P
Sbjct: 98 ----CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPM 153
Query: 212 HDKMGVPI----CGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAY 266
C C R I+ G+ + AL KQWH+ F C C K G + K G Y
Sbjct: 154 SSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPY 212
Query: 267 CETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLT 313
CE Y LFG C C I G V+ A +K + SC CS CN T
Sbjct: 213 CEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFT 259
Score = 98.2 bits (243), Expect = 1e-20
Identities = 58/201 (28%), Positives = 84/201 (41%), Gaps = 5/201 (2%)
Query: 58 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNW 117
+H CF C C +G F+ G C D+Q ++ C CGEF+ G V+ A+ +
Sbjct: 58 FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTY 117
Query: 118 HPGCFRCELCDVELADLGFVKNAGRH-LCRPCHNREKAKGLGKYICQRC----HLVIDEQ 172
HP CF C +C V GR LC+ C + C + + Q
Sbjct: 118 HPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQ 177
Query: 173 PLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVV 232
L+ +H F C CGK LT E G YC + + C AC + I G+V+
Sbjct: 178 ALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVL 237
Query: 233 NALGKQWHVEHFVCAKCEKPF 253
A K +H C++C + F
Sbjct: 238 EAGDKHYHPSCARCSRCNQMF 258
Score = 78.6 bits (192), Expect = 8e-15
Identities = 47/157 (29%), Positives = 68/157 (43%), Gaps = 16/157 (10%)
Query: 50 IVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGR----KYCEHDF-----QMLFAPCCGS 100
+V + G+ YH +CF C C RPFP G F GR + C + F+ C
Sbjct: 109 VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAG 168
Query: 101 CGEFI-IGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGK 159
CG I G+ + A++ WH GCF+C+ C L ++ G C + +GL
Sbjct: 169 CGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTG-EYISKDGAPYC-----EKDYQGLFG 222
Query: 160 YICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELT 196
C+ CH I + L YHP C+ C + T
Sbjct: 223 VKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFT 259
Score = 32.0 bits (71), Expect = 0.89
Identities = 11/42 (26%), Positives = 20/42 (47%)
Query: 279 CYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVE 320
C+ C +G+V+ K + + CF+C C L F++
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIK 80
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 114 bits (285), Expect = 1e-25
Identities = 72/227 (31%), Positives = 97/227 (42%), Gaps = 17/227 (7%)
Query: 98 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157
C CGE G V++ ++H CF C++C +LA GF G +LC + R
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR- 97
Query: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLPC 211
C C ++ + + YHP+ F CT C G +T R+ +L P
Sbjct: 98 ----CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPM 153
Query: 212 HDKMGVPI----CGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAY 266
C C R I+ G+ + AL KQWH+ F C C K G + K G Y
Sbjct: 154 SSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPY 212
Query: 267 CETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLT 313
CE Y LFG C C I G V+ A +K + SC CS CN T
Sbjct: 213 CEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFT 259
Score = 98.2 bits (243), Expect = 1e-20
Identities = 58/201 (28%), Positives = 84/201 (41%), Gaps = 5/201 (2%)
Query: 58 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNW 117
+H CF C C +G F+ G C D+Q ++ C CGEF+ G V+ A+ +
Sbjct: 58 FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTY 117
Query: 118 HPGCFRCELCDVELADLGFVKNAGRH-LCRPCHNREKAKGLGKYICQRC----HLVIDEQ 172
HP CF C +C V GR LC+ C + C + + Q
Sbjct: 118 HPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQ 177
Query: 173 PLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVV 232
L+ +H F C CGK LT E G YC + + C AC + I G+V+
Sbjct: 178 ALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVL 237
Query: 233 NALGKQWHVEHFVCAKCEKPF 253
A K +H C++C + F
Sbjct: 238 EAGDKHYHPSCARCSRCNQMF 258
Score = 78.6 bits (192), Expect = 8e-15
Identities = 47/157 (29%), Positives = 68/157 (43%), Gaps = 16/157 (10%)
Query: 50 IVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGR----KYCEHDF-----QMLFAPCCGS 100
+V + G+ YH +CF C C RPFP G F GR + C + F+ C
Sbjct: 109 VVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAG 168
Query: 101 CGEFI-IGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGK 159
CG I G+ + A++ WH GCF+C+ C L ++ G C + +GL
Sbjct: 169 CGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTG-EYISKDGAPYC-----EKDYQGLFG 222
Query: 160 YICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELT 196
C+ CH I + L YHP C+ C + T
Sbjct: 223 VKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFT 259
Score = 32.0 bits (71), Expect = 0.89
Identities = 11/42 (26%), Positives = 20/42 (47%)
Query: 279 CYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVE 320
C+ C +G+V+ K + + CF+C C L F++
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIK 80
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.477
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,902,549
Number of Sequences: 37866
Number of extensions: 794288
Number of successful extensions: 4892
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 209
Number of HSP's that attempted gapping in prelim test: 3161
Number of HSP's gapped (non-prelim): 1074
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.