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Search of human proteins with 238624257
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238624257 insulin-like growth factor 2 mRNA binding protein
1 isoform 2 [Homo sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 861 0.0
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 601 e-172
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 459 e-129
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 433 e-121
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 400 e-112
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 72 8e-13
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 72 8e-13
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 71 2e-12
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 70 3e-12
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 70 3e-12
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 70 3e-12
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 70 3e-12
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 70 3e-12
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 70 3e-12
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 70 3e-12
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 69 6e-12
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 69 1e-11
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 67 2e-11
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 65 1e-10
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 65 1e-10
gi|17402900 far upstream element-binding protein [Homo sapiens] 64 3e-10
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 61 2e-09
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 59 7e-09
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 59 9e-09
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 59 9e-09
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 59 9e-09
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 59 1e-08
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 59 1e-08
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 59 1e-08
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 57 4e-08
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 861 bits (2225), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 121 VVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLT 180
VVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLT
Sbjct: 121 VVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLT 180
Query: 181 LYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPAS 240
LYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPAS
Sbjct: 181 LYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPAS 240
Query: 241 SSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASI 300
SSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASI
Sbjct: 241 SSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASI 300
Query: 301 KIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAA 360
KIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAA
Sbjct: 301 KIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAA 360
Query: 361 GRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQ 420
GRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQ
Sbjct: 361 GRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQ 420
Query: 421 VKQQHQKGQSNQAQARRK 438
VKQQHQKGQSNQAQARRK
Sbjct: 421 VKQQHQKGQSNQAQARRK 438
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 601 bits (1550), Expect = e-172
Identities = 314/360 (87%), Positives = 325/360 (90%), Gaps = 6/360 (1%)
Query: 85 IRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA------VVNVTYSNREQTRQADEV 138
IRNI Q + ++ G E V++ E ++ + + + T+ ADEV
Sbjct: 218 IRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEV 277
Query: 139 PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCC 198
PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCC
Sbjct: 278 PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCC 337
Query: 199 RAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYS 258
RAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYS
Sbjct: 338 RAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYS 397
Query: 259 SFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIIT 318
SFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIIT
Sbjct: 398 SFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIIT 457
Query: 319 GPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLT 378
GPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLT
Sbjct: 458 GPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLT 517
Query: 379 AAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 438
AAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK
Sbjct: 518 AAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 577
Score = 290 bits (741), Expect = 2e-78
Identities = 200/498 (40%), Positives = 263/498 (52%), Gaps = 112/498 (22%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 121 VVNVTYS---------------------------------------------NREQTRQA 135
VVNVTYS +R Q RQ
Sbjct: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQG 180
Query: 136 D-------------EVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLY 182
++PL++L +VG +IGKEG ++ + + T++KI + ++
Sbjct: 181 SPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGA- 239
Query: 183 NPERTITVKGAIENC---CRAEQEIM-KKVREAYENDVAAMSLQSH------LI--PGLN 230
E+ I+V E C C+ EIM K+ ++ D + + +H LI G N
Sbjct: 240 -AEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRN 298
Query: 231 LAAVGLFPASSSAVPP--------PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAII 282
L V + + P ++T + +A ++ M +V + A +
Sbjct: 299 LKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAM 358
Query: 283 GKK-----GQHIKQLSRFASASIKIAPPETPDSKVRMVIITG-PPEAQFKAQGRIYGKLK 336
+ G ++ + F ++S + PP P S +TG P + F
Sbjct: 359 SLQSHLIPGLNLAAVGLFPASSSAVPPP--PSS------VTGAAPYSSFMQ--------- 401
Query: 337 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQV 396
P++E+ + +PA A G +IGK G+ + +L +A + + +TPD ++
Sbjct: 402 -----APEQEM---VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRM 453
Query: 397 IVKIIGHFYASQMAQRKI 414
++ I G A AQ +I
Sbjct: 454 VI-ITGPPEAQFKAQGRI 470
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 459 bits (1181), Expect = e-129
Identities = 234/324 (72%), Positives = 274/324 (84%), Gaps = 8/324 (2%)
Query: 120 AVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDL 179
+++ + + + + +E+PLKILAHNNFVGRLIGKEGRNLKK+EQDT+TKITIS LQ+L
Sbjct: 259 SILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQEL 318
Query: 180 TLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPA 239
TLYNPERTITVKG +E C +AE+EIMKK+RE+YEND+A+M+LQ+HLIPGLNL A+GLFP
Sbjct: 319 TLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPP 378
Query: 240 SSSAVPP---PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFA 296
+S PP PPS++T PY F Q+ E E V +FIPA +VGAIIGK+GQHIKQLSRFA
Sbjct: 379 TSGMPPPTSGPPSAMT--PPYPQFEQS-ETETVHLFIPALSVGAIIGKQGQHIKQLSRFA 435
Query: 297 SASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVP 356
ASIKIAP E PD+KVRMVIITGPPEAQFKAQGRIYGK+KEENF PKEEVKLE HIRVP
Sbjct: 436 GASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVP 495
Query: 357 ASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRD 416
+ AAGRVIGKGGKTVNELQNL++AEVVVPRDQTPDENDQV+VKI GHFYA Q+AQRKI++
Sbjct: 496 SFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQE 555
Query: 417 ILAQVKQQHQKG--QSNQAQARRK 438
IL QVKQ Q+ QS Q+RRK
Sbjct: 556 ILTQVKQHQQQKALQSGPPQSRRK 579
Score = 229 bits (583), Expect = 5e-60
Identities = 157/485 (32%), Positives = 238/485 (49%), Gaps = 86/485 (17%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNL+E+ P+DLE +F + KI SG FLVK+GYAFVDCPDE WA+KAIE SGK
Sbjct: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
+EL GK +E+EHSVPK+QR RK+QIRNIPP L+WEVLDSLL QYG VE+CEQVNT+SETA
Sbjct: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
Query: 121 VVNVTYSNREQTRQADE----------------VPLKILAHNNFVGRLIGKEGRNLK-KV 163
VVNVTYS+++Q RQA + +P ++ A N + + G+ G +
Sbjct: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
Query: 164 EQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQS 223
Q + ++ DL P R + + E ++ + + ++ + ++
Sbjct: 181 RQGSPGSVSKQKPCDL----PLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN 236
Query: 224 HLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEM-------VQVFIPAQ 276
G S + + P + M Q++ +++
Sbjct: 237 ----------AGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNN 286
Query: 277 AVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEAQFKAQGRIYGK 334
VG +IGK+G+++K++ + I I+P + T + R + + G E KA+ I K
Sbjct: 287 FVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKK 346
Query: 335 LKEE-----------------------NFFGPK---------------------EEVKLE 350
++E F P E+ + E
Sbjct: 347 IRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETE 406
Query: 351 T-HIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQM 409
T H+ +PA + G +IGK G+ + +L A + + + PD ++++ I G A
Sbjct: 407 TVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVI-ITGPPEAQFK 465
Query: 410 AQRKI 414
AQ +I
Sbjct: 466 AQGRI 470
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 433 bits (1113), Expect = e-121
Identities = 226/357 (63%), Positives = 267/357 (74%), Gaps = 24/357 (6%)
Query: 106 TVENCEQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQ 165
T+ + +E+ ++ + ++T+ A+E+PLKILAHN VGRLIGKEGRNLKK+E
Sbjct: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
Query: 166 DTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHL 225
+T TKITISSLQDL++YNPERTITVKG +E C AE EIMKK+REA+END+ A++ Q++L
Sbjct: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQANL 362
Query: 226 IPGLNLAAVGLFPASSSAVPPP--PSSVTGAAPYSSFM---------------------- 261
IPGLNL+A+G+F S + PP P AAPY F
Sbjct: 363 IPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHH 422
Query: 262 QAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPP 321
PEQE+V +FIP QAVGAIIGKKG HIKQL+RFA ASIKIAP E PD RMVIITGPP
Sbjct: 423 SYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPP 482
Query: 322 EAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 381
EAQFKAQGRI+GKLKEENFF PKEEVKLE HIRVP+S AGRVIGKGGKTVNELQNLT+AE
Sbjct: 483 EAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAE 542
Query: 382 VVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 438
V+VPRDQTPDEN++VIV+IIGHF+ASQ AQRKIR+I+ QVKQQ QK A R K
Sbjct: 543 VIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 599
Score = 216 bits (550), Expect = 3e-56
Identities = 169/513 (32%), Positives = 245/513 (47%), Gaps = 121/513 (23%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNL+ +VT DL ++F + K+ +GQ L+KSGYAFVD PD++WA++AIET SGK
Sbjct: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
VEL GK +E+++SV KK RSRKIQIRNIPP L+WEVLD LLAQYGTVEN EQVNT++ETA
Sbjct: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
Query: 121 VVNVTY-----------------------------------------------SNREQ-- 131
VVNVTY S+REQ
Sbjct: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGH 181
Query: 132 ----TRQADEV--PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPE 185
T QA ++ PL+IL FVG +IGKEG +K + + T++++ I ++ E
Sbjct: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA--AE 239
Query: 186 RTITVKGAIE---NCCRAEQEIMKKVREAYENDVAA---------MSLQSHLI--PGLNL 231
+ +T+ E CR EIM+K EA E +A L LI G NL
Sbjct: 240 KPVTIHATPEGTSEACRMILEIMQK--EADETKLAEEIPLKILAHNGLVGRLIGKEGRNL 297
Query: 232 --------AAVGLFPASSSAVPPPPSSVTGAAPYSS-----------FMQAPEQEMVQVF 272
+ + ++ P ++T + +A E +M+ V
Sbjct: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
Query: 273 IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEA---QFKAQG 329
A + G ++ L F++ ++PP P PP A F
Sbjct: 358 QQANLI------PGLNLSALGIFSTGLSVLSPPAGPRG--------APPAAPYHPFTTHS 403
Query: 330 RIYGKLKEENFFG--------PKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 381
+ L + FG P++E+ ++ +P A G +IGK G + +L A
Sbjct: 404 GYFSSLYPHHQFGPFPHHHSYPEQEI---VNLFIPTQAVGAIIGKKGAHIKQLARFAGAS 460
Query: 382 VVVPRDQTPDENDQVIVKIIGHFYASQMAQRKI 414
+ + + PD ++++++ I G A AQ +I
Sbjct: 461 IKIAPAEGPDVSERMVI-ITGPPEAQFKAQGRI 492
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 400 bits (1029), Expect = e-112
Identities = 213/333 (63%), Positives = 249/333 (74%), Gaps = 19/333 (5%)
Query: 106 TVENCEQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQ 165
T+ + +E+ ++ + ++T+ A+E+PLKILAHN VGRLIGKEGRNLKK+E
Sbjct: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
Query: 166 DTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHL 225
+T TKITISSLQDL++YNPERTITVKG +E C AE EIMKK+REA+END+ A++ S
Sbjct: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHS-- 360
Query: 226 IPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKK 285
G F SS P P+ PEQE+V +FIP QAVGAIIGKK
Sbjct: 361 ---------GYF---SSLYPHHQFG-----PFPHHHSYPEQEIVNLFIPTQAVGAIIGKK 403
Query: 286 GQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKE 345
G HIKQL+RFA ASIKIAP E PD RMVIITGPPEAQFKAQGRI+GKLKEENFF PKE
Sbjct: 404 GAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKE 463
Query: 346 EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFY 405
EVKLE HIRVP+S AGRVIGKGGKTVNELQNLT+AEV+VPRDQTPDEN++VIV+IIGHF+
Sbjct: 464 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 523
Query: 406 ASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 438
ASQ AQRKIR+I+ QVKQQ QK A R K
Sbjct: 524 ASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 556
Score = 219 bits (559), Expect = 3e-57
Identities = 169/503 (33%), Positives = 241/503 (47%), Gaps = 144/503 (28%)
Query: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
MNKLYIGNL+ +VT DL ++F + K+ +GQ L+KSGYAFVD PD++WA++AIET SGK
Sbjct: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
Query: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
VEL GK +E+++SV KK RSRKIQIRNIPP L+WEVLD LLAQYGTVEN EQVNT++ETA
Sbjct: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
Query: 121 VVNVTY-----------------------------------------------SNREQ-- 131
VVNVTY S+REQ
Sbjct: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGH 181
Query: 132 ----TRQADEV--PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPE 185
T QA ++ PL+IL FVG +IGKEG +K + + T++++ I ++ E
Sbjct: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA--AE 239
Query: 186 RTITVKGAIE---NCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSS 242
+ +T+ E CR EIM+K EA E +A IP LA GL
Sbjct: 240 KPVTIHATPEGTSEACRMILEIMQK--EADETKLA------EEIPLKILAHNGL------ 285
Query: 243 AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKI 302
VG +IGK+G+++K++ I I
Sbjct: 286 -----------------------------------VGRLIGKEGRNLKKIEHETGTKITI 310
Query: 303 APPETPD--SKVRMVIITGPPEAQFKAQGRIYGKLKE---------------------EN 339
+ + + R + + G EA A+ I KL+E +
Sbjct: 311 SSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHH 370
Query: 340 FFG--------PKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 391
FG P++E+ ++ +P A G +IGK G + +L A + + + PD
Sbjct: 371 QFGPFPHHHSYPEQEI---VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD 427
Query: 392 ENDQVIVKIIGHFYASQMAQRKI 414
++++++ I G A AQ +I
Sbjct: 428 VSERMVI-ITGPPEAQFKAQGRI 449
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 72.4 bits (176), Expect = 8e-13
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R+V ITGP +A FKA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 104
Query: 329 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I K +E+ + + + VPAS G +IGKGG + E++ T A+V
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ +
Sbjct: 165 VAGDMLPNSTERAV 178
Score = 61.6 bits (148), Expect = 1e-09
Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 45/184 (24%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G +KK+ +++ +I IS PER +T+ G + +
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN-----CPERIVTITGPTDAIFK 102
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I K E N + ++S A PP +
Sbjct: 103 AFAMIAYKFEEDIINSM----------------------SNSPATSKPPVT--------- 131
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
+++ +PA G++IGK G IK++ A +++A P+S R V I+G
Sbjct: 132 ---------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISG 182
Query: 320 PPEA 323
P+A
Sbjct: 183 TPDA 186
Score = 59.7 bits (143), Expect = 5e-09
Identities = 51/213 (23%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 138 VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENC 197
V L+++ + G LIGK G +K++ + T ++ ++ D+ + ER +T+ G +
Sbjct: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAI 187
Query: 198 CRAEQEIMKKVREAYE------------NDVAAMSLQSHLIPGLNLAAVGLFPASSSAVP 245
+ ++I + EAY + +++Q P L FP +
Sbjct: 188 IQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPA-FPGEKLPLH 246
Query: 246 PPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPP 305
+ S +P ++ IP +G IIG++G I ++ + + A IKIA
Sbjct: 247 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA-N 305
Query: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338
T S R + ITG P AQ I +L E
Sbjct: 306 ATEGSSERQITITGTPANISLAQYLINARLTSE 338
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 72.4 bits (176), Expect = 8e-13
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R+V ITGP +A FKA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 104
Query: 329 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I K +E+ + + + VPAS G +IGKGG + E++ T A+V
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ +
Sbjct: 165 VAGDMLPNSTERAV 178
Score = 61.6 bits (148), Expect = 1e-09
Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 45/184 (24%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G +KK+ +++ +I IS PER +T+ G + +
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNC-----PERIVTITGPTDAIFK 102
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I K E N ++ +S A PP ++
Sbjct: 103 AFAMIAYKFEEDIINSMS----------------------NSPATSKPPVTL-------- 132
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
++ +PA G++IGK G IK++ A +++A P+S R V I+G
Sbjct: 133 ----------RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISG 182
Query: 320 PPEA 323
P+A
Sbjct: 183 TPDA 186
Score = 50.4 bits (119), Expect = 3e-06
Identities = 57/238 (23%), Positives = 96/238 (40%), Gaps = 40/238 (16%)
Query: 138 VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENC 197
V L+++ + G LIGK G +K++ + T ++ ++ D+ + ER +T+ G +
Sbjct: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAI 187
Query: 198 CRAEQEIMKKVREA--------YENDVAAMSL-----QSHLIPGLNLAA-----VGLFPA 239
+ ++I + E+ Y A+ + Q++ I G L
Sbjct: 188 IQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQL 247
Query: 240 SSSAVPPPPSSVTGAA------PYSSFMQA-------------PEQEMVQVFIPAQAVGA 280
+ P PP T A P S +A P ++ IP +G
Sbjct: 248 AMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGC 307
Query: 281 IIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338
IIG++G I ++ + + A IKIA T S R + ITG P AQ I +L E
Sbjct: 308 IIGRQGTKINEIRQMSGAQIKIA-NATEGSSERQITITGTPANISLAQYLINARLTSE 364
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 71.2 bits (173), Expect = 2e-12
Identities = 44/136 (32%), Positives = 74/136 (54%), Gaps = 12/136 (8%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ +TGP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPE---RIITLTGPTNAIFKAF 72
Query: 329 GRIYGKLKEE-------NFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 381
I KL+E+ + + V L + VPA+ G +IGKGG + E++ T A+
Sbjct: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLR--LVVPATQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 382 VVVPRDQTPDENDQVI 397
V V D P+ ++ I
Sbjct: 131 VQVAGDMLPNSTERAI 146
Score = 60.5 bits (145), Expect = 3e-09
Identities = 54/230 (23%), Positives = 99/230 (43%), Gaps = 47/230 (20%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G ++K++ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNC-----PERIITLTGPTNAIFK 70
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I+ K+ E + + +S+A PP ++
Sbjct: 71 AFAMIIDKLEEDINSSMT----------------------NSTAASRPPVTL-------- 100
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 101 ----------RLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 320 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 369
P++ + +I + E P+ V + +PAS+ VI GG+
Sbjct: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSP--VICAGGQ 198
Score = 47.8 bits (112), Expect = 2e-05
Identities = 63/287 (21%), Positives = 109/287 (37%), Gaps = 64/287 (22%)
Query: 111 EQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 170
+++ + +++ N T ++R V L+++ G LIGK G +K++ + T +
Sbjct: 77 DKLEEDINSSMTNSTAASRPP------VTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 171 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE----------------- 213
+ ++ D+ + ER IT+ G ++ ++I + E
Sbjct: 131 VQVAG--DMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPA 188
Query: 214 -------------NDVA---------------AMSLQS-HLIPGLNLAAVGLFPASSS-- 242
+D A A S+Q H I L+LA + S
Sbjct: 189 SSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHF 248
Query: 243 -------AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRF 295
SS Y + + A Q ++ IP +G IIG++G +I ++ +
Sbjct: 249 AMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQM 308
Query: 296 ASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFG 342
+ A IKIA P S R V ITG + AQ I +L E G
Sbjct: 309 SGAQIKIANP-VEGSSGRQVTITGSAASISLAQYLINARLSSEKGMG 354
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 70.5 bits (171), Expect = 3e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I+ K+ E + + +S+A PP +
Sbjct: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 320 PPEA 323
P++
Sbjct: 151 IPQS 154
Score = 54.7 bits (130), Expect = 2e-07
Identities = 57/247 (23%), Positives = 105/247 (42%), Gaps = 31/247 (12%)
Query: 111 EQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 170
+++ + +++ N T ++R V L+++ + G LIGK G +K++ + T +
Sbjct: 77 DKLEEDISSSMTNSTAASRPP------VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 171 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA------------- 217
+ ++ D+ + ER IT+ G ++ ++I + E+ V
Sbjct: 131 VQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVI 188
Query: 218 -----AMSLQS-HLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQV 271
A ++Q + IP +L + S P + +A + Q E+
Sbjct: 189 FAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELT-- 246
Query: 272 FIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRI 331
IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ I
Sbjct: 247 -IPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQYLI 304
Query: 332 YGKLKEE 338
+L E
Sbjct: 305 NVRLSSE 311
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 70.5 bits (171), Expect = 3e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 59.3 bits (142), Expect = 7e-09
Identities = 53/230 (23%), Positives = 97/230 (42%), Gaps = 48/230 (20%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I+ K+ E + + +S+A PP +
Sbjct: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 320 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 369
P++ + +I + E P + V + P ++ VI GG+
Sbjct: 151 IPQSIIECVKQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
Score = 46.6 bits (109), Expect = 4e-05
Identities = 58/261 (22%), Positives = 108/261 (41%), Gaps = 42/261 (16%)
Query: 111 EQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 170
+++ + +++ N T ++R V L+++ + G LIGK G +K++ + T +
Sbjct: 77 DKLEEDISSSMTNSTAASRPP------VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 171 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA------------- 217
+ ++ D+ + ER IT+ G ++ ++I + E
Sbjct: 131 VQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSS 188
Query: 218 ---------AMSLQS-HLIPGLNLAAVGLFPASSSAVPPPP-----SSVTGAAP----YS 258
A ++Q + IP +L + S P S + ++P Y
Sbjct: 189 SPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW 248
Query: 259 SFMQAPEQEMV-QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVII 317
+ + A Q ++ IP +G IIG++G I ++ + + A IKIA P S R V I
Sbjct: 249 AGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTI 307
Query: 318 TGPPEAQFKAQGRIYGKLKEE 338
TG + AQ I +L E
Sbjct: 308 TGSAASISLAQYLINVRLSSE 328
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 70.5 bits (171), Expect = 3e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I+ K+ E + + +S+A PP +
Sbjct: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 320 PPEA 323
P++
Sbjct: 151 IPQS 154
Score = 38.5 bits (88), Expect = 0.012
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
++ IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 287 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 345
Query: 330 RIYGKLKEE 338
I +L E
Sbjct: 346 LINVRLSSE 354
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 70.5 bits (171), Expect = 3e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 59.3 bits (142), Expect = 7e-09
Identities = 53/230 (23%), Positives = 97/230 (42%), Gaps = 48/230 (20%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I+ K+ E + + +S+A PP +
Sbjct: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 320 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 369
P++ + +I + E P + V + P ++ VI GG+
Sbjct: 151 IPQSIIECVKQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
Score = 38.5 bits (88), Expect = 0.012
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
++ IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 349
Query: 330 RIYGKLKEE 338
I +L E
Sbjct: 350 LINVRLSSE 358
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 70.5 bits (171), Expect = 3e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I+ K+ E + + +S+A PP +
Sbjct: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 320 PPEA 323
P++
Sbjct: 151 IPQS 154
Score = 38.5 bits (88), Expect = 0.012
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
++ IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 288 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 346
Query: 330 RIYGKLKEE 338
I +L E
Sbjct: 347 LINVRLSSE 355
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 70.5 bits (171), Expect = 3e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 59.3 bits (142), Expect = 7e-09
Identities = 53/230 (23%), Positives = 97/230 (42%), Gaps = 48/230 (20%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I+ K+ E + + +S+A PP +
Sbjct: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 320 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 369
P++ + +I + E P + V + P ++ VI GG+
Sbjct: 151 IPQSIIECVKQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
Score = 38.5 bits (88), Expect = 0.012
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
++ IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 292 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 350
Query: 330 RIYGKLKEE 338
I +L E
Sbjct: 351 LINVRLSSE 359
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 70.5 bits (171), Expect = 3e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
Query: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 45/184 (24%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
A I+ K+ E + + +S+A PP +
Sbjct: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
Query: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
Query: 320 PPEA 323
P++
Sbjct: 151 IPQS 154
Score = 49.7 bits (117), Expect = 5e-06
Identities = 59/257 (22%), Positives = 110/257 (42%), Gaps = 38/257 (14%)
Query: 111 EQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 170
+++ + +++ N T ++R V L+++ + G LIGK G +K++ + T +
Sbjct: 77 DKLEEDISSSMTNSTAASRPP------VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
Query: 171 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVA------------- 217
+ ++ D+ + ER IT+ G ++ ++I + E+ V
Sbjct: 131 VQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVI 188
Query: 218 -----AMSLQS-HLIPGLNLAAVGLFPASSSAVPPPP-----SSVTGAAP----YSSFMQ 262
A ++Q + IP +L + S P S + ++P Y + +
Sbjct: 189 FAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLD 248
Query: 263 APEQEMV-QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPP 321
A Q ++ IP +G IIG++G I ++ + + A IKIA P S R V ITG
Sbjct: 249 ASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSA 307
Query: 322 EAQFKAQGRIYGKLKEE 338
+ AQ I +L E
Sbjct: 308 ASISLAQYLINVRLSSE 324
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 69.3 bits (168), Expect = 6e-12
Identities = 53/185 (28%), Positives = 91/185 (49%), Gaps = 17/185 (9%)
Query: 264 PEQEMVQVF-IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPE 322
P M + + +P VG IIG+ G+ I ++ + + ++I+P ++ R V +TG PE
Sbjct: 141 PRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISP-DSGGLPERSVSLTGAPE 199
Query: 323 AQFKAQ-----------GRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTV 371
+ KA+ G G+ + G V+ I +PA AG VIGKGG+T+
Sbjct: 200 SVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQ---EIMIPAGKAGLVIGKGGETI 256
Query: 372 NELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSN 431
+LQ ++++ +D + + N ++IIG Y Q A + DIL + + Q G N
Sbjct: 257 KQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRE-RDQGGFGDRN 315
Query: 432 QAQAR 436
+ +R
Sbjct: 316 EYGSR 320
Score = 54.3 bits (129), Expect = 2e-07
Identities = 65/284 (22%), Positives = 117/284 (41%), Gaps = 49/284 (17%)
Query: 146 NNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIM 205
+ VG +IG+ G + K++QD+ K+ IS PER++++ GA E+ +A+ +
Sbjct: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL---PERSVSLTGAPESVQKAKMML- 208
Query: 206 KKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPE 265
+D+ S PP + +
Sbjct: 209 --------DDIV-----------------------SRGRGGPPGQF-----HDNANGGQN 232
Query: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKV-RMVIITGPPEAQ 324
+ ++ IPA G +IGK G+ IKQL A + + + ++ V + + I G P
Sbjct: 233 GTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKV 292
Query: 325 FKAQGRIYGKLKE--ENFFGPKEE----VKLETHIRVPASAAGRVIGKGGKTVNELQNLT 378
+A + L+E + FG + E + + VP + G VIG+ G+ + ++QN
Sbjct: 293 QQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQN-- 350
Query: 379 AAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVK 422
A V + Q + I I+G + A R I D+L ++
Sbjct: 351 DAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLR 394
Score = 43.9 bits (102), Expect = 3e-04
Identities = 44/183 (24%), Positives = 75/183 (40%), Gaps = 35/183 (19%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIK---------------IAPPETPDSKVR 313
+ V +P +VG +IG+ G+ IK++ A I+ + PP+ + R
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAAR 384
Query: 314 MV------IITGPPEAQ----FKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRV 363
++ + +GPP GR G+ + + +GP E +P G V
Sbjct: 385 IINDLLQSLRSGPPGPPGGPGMPPGGR--GRGRGQGNWGPPGG---EMTFSIPTHKCGLV 439
Query: 364 IGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHF-----YASQMAQRKIRDIL 418
IG+GG+ V + T A V + R P+ + + II +A Q+ + KI L
Sbjct: 440 IGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPL 499
Query: 419 AQV 421
V
Sbjct: 500 CPV 502
Score = 42.0 bits (97), Expect = 0.001
Identities = 50/197 (25%), Positives = 78/197 (39%), Gaps = 34/197 (17%)
Query: 149 VGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKV 208
VG +IG+ G +KK++ D +I D T PE+ + G + C A + I
Sbjct: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQ-DDGT--GPEKIAHIMGPPDRCEHAARII---- 386
Query: 209 REAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEM 268
ND+ SL+S P P P G P EM
Sbjct: 387 -----NDL-LQSLRSG-------------PPGPPGGPGMPPGGRGRGRGQGNWGPPGGEM 427
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAP--PETPDSKVRMVIITGPPEAQFK 326
IP G +IG+ G+++K +++ A ++I+ P D ++ II G P+
Sbjct: 428 T-FSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDH 486
Query: 327 AQGRIYGKLKEENFFGP 343
A+ +L EE GP
Sbjct: 487 AK-----QLIEEKIEGP 498
Score = 33.1 bits (74), Expect = 0.51
Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 343 PKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQ--TPDENDQVIVKI 400
P + RVP G +IG+GG+ +N++Q + +V + D P+ + V +
Sbjct: 139 PPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERS----VSL 194
Query: 401 IGHFYASQMAQRKIRDILAQ 420
G + Q A+ + DI+++
Sbjct: 195 TGAPESVQKAKMMLDDIVSR 214
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 68.6 bits (166), Expect = 1e-11
Identities = 55/213 (25%), Positives = 99/213 (46%), Gaps = 8/213 (3%)
Query: 127 SNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPER 186
+ R T + + LK+L + G +IGK G+ + +++++T I +S +D ER
Sbjct: 39 TKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 98
Query: 187 TITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPP 246
++G +E I +K+RE +N VA S L P + P P
Sbjct: 99 VCLIQGTVEALNAVHGFIAEKIREMPQN-VAKTEPVSILQPQTTVN-----PDRIKQTLP 152
Query: 247 PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA-PP 305
+ T ++P S M V++ +P G IIGK G +K + + A ++++ P
Sbjct: 153 SSPTTTKSSP-SDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 211
Query: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338
+ + + R+V ++G PE KA I K++E+
Sbjct: 212 DGINLQERVVTVSGEPEQNRKAVELIIQKIQED 244
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/203 (24%), Positives = 84/203 (41%), Gaps = 43/203 (21%)
Query: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 323
Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA
Sbjct: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Query: 324 QFKAQGRIYGKLKEE----------NFFGPKEEVKLE----------------------- 350
G I K++E + P+ V +
Sbjct: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTT 168
Query: 351 -----THIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFY 405
I VP S AG +IGKGG TV + + A V + + + +V + G
Sbjct: 169 SRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE-- 226
Query: 406 ASQMAQRKIRDILAQVKQQHQKG 428
+ ++ + I+ ++++ Q G
Sbjct: 227 -PEQNRKAVELIIQKIQEDPQSG 248
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEA 323
+++V++ +P VGAI+GK G+ + + A I+I+ P ++ R V ITG P A
Sbjct: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
Query: 324 QFKAQGRIYGKLKEE 338
AQ I ++ E
Sbjct: 481 TQAAQYLITQRITYE 495
Score = 38.5 bits (88), Expect = 0.012
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 14/83 (16%)
Query: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIG 365
+ PDS+ R + PPEA G K N E+ + + +P+ AAG +IG
Sbjct: 21 DPPDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQYFLKVLIPSYAAGSIIG 66
Query: 366 KGGKTVNELQNLTAAEVVVPRDQ 388
KGG+T+ +LQ T A + + + +
Sbjct: 67 KGGQTIVQLQKETGATIKLSKSK 89
Score = 37.0 bits (84), Expect = 0.035
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 337 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 394
E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P +
Sbjct: 414 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 469
Query: 395 QVIVKIIGHFYASQMAQ 411
+ V I G A+Q AQ
Sbjct: 470 RK-VTITGTPAATQAAQ 485
Score = 33.9 bits (76), Expect = 0.30
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189
E++ + ++I N VG ++GK G+ L + ++ T +I IS + R +T
Sbjct: 414 EKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 473
Query: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 222
+ G A+ I +++ YE V A + Q
Sbjct: 474 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 504
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 67.4 bits (163), Expect = 2e-11
Identities = 46/169 (27%), Positives = 87/169 (51%), Gaps = 7/169 (4%)
Query: 273 IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIY 332
+P + VG IIG+ G+ I ++ + I+IA E+ R ++TG PE+ +A+ R+
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIAS-ESSGIPERPCVLTGTPESIEQAK-RLL 141
Query: 333 GKLKEENFFGPKEEVKLETH-----IRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 387
G++ + GP ++++ I +PAS G VIG+GG+T+ +LQ T ++V+ +D
Sbjct: 142 GQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201
Query: 388 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQAR 436
++I G + Q A+ + +I+ + Q +G +R
Sbjct: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSR 250
Score = 52.4 bits (124), Expect = 8e-07
Identities = 74/321 (23%), Positives = 123/321 (38%), Gaps = 80/321 (24%)
Query: 146 NNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKG---AIENCCRAEQ 202
+ VG +IG+ G + +++ ++ KI I+S PER + G +IE R
Sbjct: 86 DKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI---PERPCVLTGTPESIEQAKRLLG 142
Query: 203 EIMKKVREA--YENDVAAMS-LQSHLIPGLNLAAV---------------GLFPASSSAV 244
+I+ + R + ND+ + S +Q LIP + V G+
Sbjct: 143 QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDG 202
Query: 245 PPP-----PSSVTGAAPYSSFMQAPEQEM--------------------------VQVFI 273
P P P +TG A QA E + ++V +
Sbjct: 203 PLPTGADKPLRITGDA--FKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSV 260
Query: 274 PAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYG 333
P AVG +IG+ G+ IK++ A I+ P + S R + GPP+ + + I
Sbjct: 261 PRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGI-SPERAAQVMGPPD-RCQHAAHIIS 318
Query: 334 KL----KEENFFGPKEEVK-----------------LETHIRVPASAAGRVIGKGGKTVN 372
+L +E + FG + E VPA G VIGKGG+ +
Sbjct: 319 ELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIK 378
Query: 373 ELQNLTAAEVVVPRDQTPDEN 393
+ + A V + R+ P+ +
Sbjct: 379 SINQQSGAHVELQRNPPPNSD 399
Score = 32.3 bits (72), Expect = 0.87
Identities = 29/110 (26%), Positives = 40/110 (36%), Gaps = 18/110 (16%)
Query: 150 GRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVR 209
G +IGK G N+K + Q + + + R T++G + A Q I +KV
Sbjct: 367 GLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVG 426
Query: 210 EAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
G NL A G F S + PP P P SS
Sbjct: 427 ------------------GTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSS 458
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 65.1 bits (157), Expect = 1e-10
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ +SA I I+ P+ R+ ITG A F A
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGSTAAVFHAV 76
Query: 329 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL E+ P + + +PAS G +IGK G + E++ T A+V
Sbjct: 77 SMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQ 136
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ +
Sbjct: 137 VAGDLLPNSTERAV 150
Score = 61.6 bits (148), Expect = 1e-09
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 45/194 (23%)
Query: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189
E+ + + L++L H VG +IGK+G +K++ + + +ITIS PER T
Sbjct: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITT 64
Query: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPS 249
+ G+ A I K+ E D+ A PA+ V PP
Sbjct: 65 ITGSTAAVFHAVSMIAFKLDE----DLCAA------------------PANGGNVSRPPV 102
Query: 250 SVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPD 309
+ +++ IPA G++IGK G IK++ A +++A P+
Sbjct: 103 T------------------LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPN 144
Query: 310 SKVRMVIITGPPEA 323
S R V ++G P+A
Sbjct: 145 STERAVTVSGVPDA 158
Score = 52.4 bits (124), Expect = 8e-07
Identities = 56/210 (26%), Positives = 95/210 (45%), Gaps = 28/210 (13%)
Query: 138 VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENC 197
V L+++ + G LIGK G +K++ + T ++ ++ DL + ER +TV G +
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAI 159
Query: 198 CRAEQEIMKKVREAYENDVA-----AMSLQSHLIPGLNLAAV-----GLFPA-------- 239
++I + E+ ++SL + L+ +V + PA
Sbjct: 160 ILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQL 219
Query: 240 SSSAVP-PPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASA 298
SS AVP PS V G P + Q QE + +P +G +IG++G I ++ + + A
Sbjct: 220 SSHAVPFATPSVVPGLDPGT---QTSSQEFL---VPNDLIGCVIGRQGSKISEIRQMSGA 273
Query: 299 SIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
IKI + + R V ITG P + AQ
Sbjct: 274 HIKIG-NQAEGAGERHVTITGSPVSIALAQ 302
Score = 32.7 bits (73), Expect = 0.67
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 333 GKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDE 392
G L+EE P+ + L + + G +IGK G+TV ++ ++A + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
Query: 393 NDQVIVKIIGHFYASQMAQRKIRDIL 418
+ F+A M K+ + L
Sbjct: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 65.1 bits (157), Expect = 1e-10
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 8/134 (5%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
+++ + + VG+IIGKKG+ +K++ +SA I I+ P+ R+ ITG A F A
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE---RITTITGSTAAVFHAV 76
Query: 329 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
I KL E+ P + + +PAS G +IGK G + E++ T A+V
Sbjct: 77 SMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQ 136
Query: 384 VPRDQTPDENDQVI 397
V D P+ ++ +
Sbjct: 137 VAGDLLPNSTERAV 150
Score = 61.6 bits (148), Expect = 1e-09
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 45/194 (23%)
Query: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189
E+ + + L++L H VG +IGK+G +K++ + + +ITIS PER T
Sbjct: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITT 64
Query: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPS 249
+ G+ A I K+ E D+ A PA+ V PP
Sbjct: 65 ITGSTAAVFHAVSMIAFKLDE----DLCAA------------------PANGGNVSRPPV 102
Query: 250 SVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPD 309
+ +++ IPA G++IGK G IK++ A +++A P+
Sbjct: 103 T------------------LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPN 144
Query: 310 SKVRMVIITGPPEA 323
S R V ++G P+A
Sbjct: 145 STERAVTVSGVPDA 158
Score = 52.4 bits (124), Expect = 8e-07
Identities = 56/210 (26%), Positives = 95/210 (45%), Gaps = 28/210 (13%)
Query: 138 VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENC 197
V L+++ + G LIGK G +K++ + T ++ ++ DL + ER +TV G +
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAI 159
Query: 198 CRAEQEIMKKVREAYENDVA-----AMSLQSHLIPGLNLAAV-----GLFPA-------- 239
++I + E+ ++SL + L+ +V + PA
Sbjct: 160 ILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQL 219
Query: 240 SSSAVP-PPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASA 298
SS AVP PS V G P + Q QE + +P +G +IG++G I ++ + + A
Sbjct: 220 SSHAVPFATPSVVPGLDPGT---QTSSQEFL---VPNDLIGCVIGRQGSKISEIRQMSGA 273
Query: 299 SIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
IKI + + R V ITG P + AQ
Sbjct: 274 HIKIG-NQAEGAGERHVTITGSPVSIALAQ 302
Score = 32.7 bits (73), Expect = 0.67
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Query: 333 GKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDE 392
G L+EE P+ + L + + G +IGK G+TV ++ ++A + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPER 61
Query: 393 NDQVIVKIIGHFYASQMAQRKIRDIL 418
+ F+A M K+ + L
Sbjct: 62 ITTITGSTAAVFHAVSMIAFKLDEDL 87
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 63.9 bits (154), Expect = 3e-10
Identities = 45/154 (29%), Positives = 81/154 (52%), Gaps = 13/154 (8%)
Query: 273 IPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIY 332
+P VG IIG+ G+ I ++ + + I+IAP ++ R ++TG PE+ A+ R+
Sbjct: 107 VPDGMVGFIIGRGGEQISRIQQESGCKIQIAP-DSGGLPERSCMLTGTPESVQSAK-RLL 164
Query: 333 GKLKEE--------NFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVV 384
++ E+ + GP V+ I +PAS AG VIGKGG+T+ +LQ ++V+
Sbjct: 165 DQIVEKGRPAPGFHHGDGPGNAVQ---EIMIPASKAGLVIGKGGETIKQLQERAGVKMVM 221
Query: 385 PRDQTPDENDQVIVKIIGHFYASQMAQRKIRDIL 418
+D + ++I G Y Q A+ + +++
Sbjct: 222 IQDGPQNTGADKPLRITGDPYKVQQAKEMVLELI 255
Score = 60.8 bits (146), Expect = 2e-09
Identities = 87/391 (22%), Positives = 160/391 (40%), Gaps = 94/391 (24%)
Query: 105 GTVENCEQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVE 164
G + ++V ++++ + +++Q+R K+ + VG +IG+ G + +++
Sbjct: 70 GDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKV--PDGMVGFIIGRGGEQISRIQ 127
Query: 165 QDTETKITISSLQDLTLYNPERTITVKG---AIENCCRAEQEIMKKVREA---YENDVAA 218
Q++ KI I+ PER+ + G ++++ R +I++K R A + D
Sbjct: 128 QESGCKIQIAPDSGGL---PERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPG 184
Query: 219 MSLQSHLIP----------------------GLNLAAVGLFPASSSAVPPPPSSVTGAAP 256
++Q +IP G+ + + P ++ A P +TG P
Sbjct: 185 NAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA--DKPLRITGD-P 241
Query: 257 YSSFMQAPEQ-------------------------EMVQVFIPAQAVGAIIGKKGQHIKQ 291
Y QA E E + V IP AVG +IG+ G+ IK+
Sbjct: 242 YK-VQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKK 300
Query: 292 LSRFASASIKIAPPE--TPDSKVRMVIITGPPE-AQFKAQ-------------------- 328
+ A I+ P + TP+ R+ ITGPP+ Q A+
Sbjct: 301 IQNDAGVRIQFKPDDGTTPE---RIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPG 357
Query: 329 GRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQ 388
GR G+ + GP ++ E + VP G +IGKGG+T+ + + A + + R+
Sbjct: 358 GRGRGRGQGNWNMGPPGGLQ-EFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNP 416
Query: 389 TPDENDQVIVKIIGHF-----YASQMAQRKI 414
P+ + + + I YA Q+ + KI
Sbjct: 417 PPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 19/179 (10%)
Query: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 323
Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA
Sbjct: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Query: 324 QFKAQGRIYGKLKE----------ENFFGPKEEVK----LETHIRVPASAAGRVIGKGGK 369
G I K++E + P+ V + I VP S AG +IGKGG
Sbjct: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
Query: 370 TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG 428
TV + + A V + + + +V + G + ++ + I+ ++++ Q G
Sbjct: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQSG 224
Score = 57.0 bits (136), Expect = 3e-08
Identities = 49/213 (23%), Positives = 92/213 (43%), Gaps = 32/213 (15%)
Query: 127 SNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPER 186
+ R T + + LK+L + G +IGK G+ + +++++T I +S +D ER
Sbjct: 39 TKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 98
Query: 187 TITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPP 246
++G +E I +K+RE +N VA S L P
Sbjct: 99 VCLIQGTVEALNAVHGFIAEKIREMPQN-VAKTEPVSILQP------------------- 138
Query: 247 PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA-PP 305
+ + + V++ +P G IIGK G +K + + A ++++ P
Sbjct: 139 -----------QTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187
Query: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338
+ + + R+V ++G PE KA I K++E+
Sbjct: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQED 220
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEA 323
+++V++ +P VGAI+GK G+ + + A I+I+ P ++ R V ITG P A
Sbjct: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
Query: 324 QFKAQGRIYGKLKEE 338
AQ I ++ E
Sbjct: 457 TQAAQYLITQRITYE 471
Score = 37.0 bits (84), Expect = 0.035
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 337 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 394
E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P +
Sbjct: 390 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
Query: 395 QVIVKIIGHFYASQMAQ 411
+ V I G A+Q AQ
Sbjct: 446 RK-VTITGTPAATQAAQ 461
Score = 33.9 bits (76), Expect = 0.30
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189
E++ + ++I N VG ++GK G+ L + ++ T +I IS + R +T
Sbjct: 390 EKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 449
Query: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 222
+ G A+ I +++ YE V A + Q
Sbjct: 450 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 480
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 59.3 bits (142), Expect = 7e-09
Identities = 53/216 (24%), Positives = 90/216 (41%), Gaps = 32/216 (14%)
Query: 124 VTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYN 183
V + R T + E LK+L + G +IGK G+ + +++++T I +S +D
Sbjct: 19 VVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGT 78
Query: 184 PERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSA 243
ER V+G E I +KVRE IP A
Sbjct: 79 TERVCLVQGTAEALNAVHSFIAEKVRE---------------IP--------------QA 109
Query: 244 VPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA 303
+ P V + M + ++ +P G IIGK G +K + + A ++++
Sbjct: 110 MTKP--EVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS 167
Query: 304 -PPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338
PE + + R+V ++G PE KA I K++E+
Sbjct: 168 QKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQED 203
Score = 55.8 bits (133), Expect = 7e-08
Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 19/174 (10%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEAQFK 326
++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ ++ G EA
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 327 AQGRIYGKLKEENFFGPKEEV--------------KLETHIRVPASAAGRVIGKGGKTVN 372
I K++E K EV + + VP S AG +IGKGG TV
Sbjct: 95 VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
Query: 373 ELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQ 426
+ + A V + + + +V + G + + + I+ +V++ Q
Sbjct: 155 AVMEQSGAWVQLSQKPEGINLQERVVTVSGE---PEQVHKAVSAIVQKVQEDPQ 205
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEA 323
+E+V++ +P VGAI+GK G+ + + A I+I+ P ++ R V ITG P A
Sbjct: 406 KELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAA 465
Query: 324 QFKAQ 328
AQ
Sbjct: 466 TQAAQ 470
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 319 GPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLT 378
GP A A G G L E E K I VP + G ++GKGGKT+ E Q LT
Sbjct: 379 GPLVAAAAAAGAAGGFLTAEKLAA--ESAKELVEIAVPENLVGAILGKGGKTLVEYQELT 436
Query: 379 AAEVVVPR 386
A + + +
Sbjct: 437 GARIQISK 444
Score = 38.1 bits (87), Expect = 0.016
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 14/84 (16%)
Query: 305 PETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVI 364
PE PDS+ R + PPE + EE + + +P+ AAG +I
Sbjct: 3 PEAPDSRKRP--LETPPEVVCTKRSNT------------GEEGEYFLKVLIPSYAAGSII 48
Query: 365 GKGGKTVNELQNLTAAEVVVPRDQ 388
GKGG+T+ +LQ T A + + + +
Sbjct: 49 GKGGQTIVQLQKETGATIKLSKSK 72
Score = 33.5 bits (75), Expect = 0.39
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
++I N VG ++GK G+ L + ++ T +I IS + R +T+ G+
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 200 AEQEIMKKVREAYENDVAAMSLQ 222
A+ I ++V YE V A + Q
Sbjct: 469 AQYLISQRV--TYEQGVRASNPQ 489
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 58.9 bits (141), Expect = 9e-09
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 28/194 (14%)
Query: 130 EQTRQADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 188
+++R DE V L+IL + G +IGK G+N+K + D +++ PER +
Sbjct: 34 KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
Query: 189 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 248
++ IE EI+KK+ E GL L + P ++S +P
Sbjct: 89 SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
Query: 249 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 308
+V Y + + +++ I G IIG KG IK+L +IK+ P
Sbjct: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
Query: 309 DSKVRMVIITGPPE 322
S R+V+I G P+
Sbjct: 187 HSTDRVVLIGGKPD 200
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
QV IP G+IIGK GQ IKQ+ + ASIKI P S+ R++ ITG + AQ
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
Query: 330 RIYGKLKE 337
+ +K+
Sbjct: 450 LLQNSVKQ 457
Score = 35.4 bits (80), Expect = 0.10
Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 408
+ T + +P AG +IGKGG+ + ++++ + A + + D+ + ++ I+ I G Q
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
Query: 409 MAQRKIRDILAQ 420
AQ +++ + Q
Sbjct: 446 NAQYLLQNSVKQ 457
Score = 32.3 bits (72), Expect = 0.87
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 391
+E I + + AG VIGKGGK + L+ A V VP P+
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 58.9 bits (141), Expect = 9e-09
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 28/194 (14%)
Query: 130 EQTRQADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 188
+++R DE V L+IL + G +IGK G+N+K + D +++ PER +
Sbjct: 34 KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
Query: 189 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 248
++ IE EI+KK+ E GL L + P ++S +P
Sbjct: 89 SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
Query: 249 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 308
+V Y + + +++ I G IIG KG IK+L +IK+ P
Sbjct: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
Query: 309 DSKVRMVIITGPPE 322
S R+V+I G P+
Sbjct: 187 HSTDRVVLIGGKPD 200
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
QV IP G+IIGK GQ IKQ+ + ASIKI P S+ R++ ITG + AQ
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
Query: 330 RIYGKLKE 337
+ +K+
Sbjct: 450 LLQNSVKQ 457
Score = 35.4 bits (80), Expect = 0.10
Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 408
+ T + +P AG +IGKGG+ + ++++ + A + + D+ + ++ I+ I G Q
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
Query: 409 MAQRKIRDILAQ 420
AQ +++ + Q
Sbjct: 446 NAQYLLQNSVKQ 457
Score = 32.3 bits (72), Expect = 0.87
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 391
+E I + + AG VIGKGGK + L+ A V VP P+
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 58.9 bits (141), Expect = 9e-09
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 28/194 (14%)
Query: 130 EQTRQADE-VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTI 188
+++R DE V L+IL + G +IGK G+N+K + D +++ PER +
Sbjct: 34 KRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERIL 88
Query: 189 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 248
++ IE EI+KK+ E GL L + P ++S +P
Sbjct: 89 SISADIETI----GEILKKIIPTLEE-------------GLQLPS----PTATSQLPLES 127
Query: 249 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 308
+V Y + + +++ I G IIG KG IK+L +IK+ P
Sbjct: 128 DAVE-CLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP 186
Query: 309 DSKVRMVIITGPPE 322
S R+V+I G P+
Sbjct: 187 HSTDRVVLIGGKPD 200
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
QV IP G+IIGK GQ IKQ+ + ASIKI P S+ R++ ITG + AQ
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEP-LEGSEDRIITITGTQDQIQNAQY 449
Query: 330 RIYGKLKE 337
+ +K+
Sbjct: 450 LLQNSVKQ 457
Score = 35.4 bits (80), Expect = 0.10
Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQ 408
+ T + +P AG +IGKGG+ + ++++ + A + + D+ + ++ I+ I G Q
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
Query: 409 MAQRKIRDILAQ 420
AQ +++ + Q
Sbjct: 446 NAQYLLQNSVKQ 457
Score = 32.3 bits (72), Expect = 0.87
Identities = 17/43 (39%), Positives = 23/43 (53%)
Query: 349 LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 391
+E I + + AG VIGKGGK + L+ A V VP P+
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPE 85
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 58.5 bits (140), Expect = 1e-08
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)
Query: 247 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 297
P S+ Y + ++ E+ + +++ +P +AV IIG++G +IKQL +
Sbjct: 24 PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
Query: 298 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 357
A I + + D R+++I+G P KA+ I+ L E + + VP
Sbjct: 84 ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
Query: 358 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 402
+ GR+IG+GG+T+ + + A++ ++ ++KI G
Sbjct: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/75 (22%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 136 DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE 195
D++ +++ V +IG++G N+K++ + T +I + D ER + + G
Sbjct: 51 DDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFPV 106
Query: 196 NCCRAEQEIMKKVRE 210
C+A+ I + + E
Sbjct: 107 QVCKAKAAIHQILTE 121
Score = 31.6 bits (70), Expect = 1.5
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 149 VGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKV 208
VGR+IG+ G ++ + + + KIT + TL R I + G + A+ I++KV
Sbjct: 136 VGRIIGRGGETIRSICKASGAKITCDKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKV 194
Query: 209 REAYE 213
E E
Sbjct: 195 SEDEE 199
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 58.5 bits (140), Expect = 1e-08
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)
Query: 247 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 297
P S+ Y + ++ E+ + +++ +P +AV IIG++G +IKQL +
Sbjct: 24 PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
Query: 298 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 357
A I + + D R+++I+G P KA+ I+ L E + + VP
Sbjct: 84 ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
Query: 358 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 402
+ GR+IG+GG+T+ + + A++ ++ ++KI G
Sbjct: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/75 (22%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 136 DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE 195
D++ +++ V +IG++G N+K++ + T +I + D ER + + G
Sbjct: 51 DDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFPV 106
Query: 196 NCCRAEQEIMKKVRE 210
C+A+ I + + E
Sbjct: 107 QVCKAKAAIHQILTE 121
Score = 31.6 bits (70), Expect = 1.5
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 149 VGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKV 208
VGR+IG+ G ++ + + + KIT + TL R I + G + A+ I++KV
Sbjct: 136 VGRIIGRGGETIRSICKASGAKITCDKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKV 194
Query: 209 REAYE 213
E E
Sbjct: 195 SEDEE 199
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 58.5 bits (140), Expect = 1e-08
Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 19/165 (11%)
Query: 247 PPSSVTGAAPYSSFMQAPEQEM---------VQVFIPAQAVGAIIGKKGQHIKQLSRFAS 297
P S+ Y + ++ E+ + +++ +P +AV IIG++G +IKQL +
Sbjct: 24 PASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTG 83
Query: 298 ASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPA 357
A I + + D R+++I+G P KA+ I+ L E + + VP
Sbjct: 84 ARIDVDTEDVGDE--RVLLISGFPVQVCKAKAAIHQIL--------TENTPVSEQLSVPQ 133
Query: 358 SAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIG 402
+ GR+IG+GG+T+ + + A++ ++ ++KI G
Sbjct: 134 RSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/75 (22%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 136 DEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE 195
D++ +++ V +IG++G N+K++ + T +I + D ER + + G
Sbjct: 51 DDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDVGDERVLLISGFPV 106
Query: 196 NCCRAEQEIMKKVRE 210
C+A+ I + + E
Sbjct: 107 QVCKAKAAIHQILTE 121
Score = 31.6 bits (70), Expect = 1.5
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 149 VGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKV 208
VGR+IG+ G ++ + + + KIT + TL R I + G + A+ I++KV
Sbjct: 136 VGRIIGRGGETIRSICKASGAKITCDKESEGTLL-LSRLIKISGTQKEVAAAKHLILEKV 194
Query: 209 REAYE 213
E E
Sbjct: 195 SEDEE 199
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 56.6 bits (135), Expect = 4e-08
Identities = 83/350 (23%), Positives = 133/350 (38%), Gaps = 88/350 (25%)
Query: 76 KKQRSRKIQ------IRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETAVVNVTYSNR 129
K +R R+I+ I N P + + L VE C + + +V +YS
Sbjct: 526 KGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSI- 584
Query: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNP-ERTI 188
VP+ H N +IGK G N+KK+ +++ TKI DL N TI
Sbjct: 585 -------SVPIFKQFHKN----IIGKGGANIKKIREESNTKI------DLPAENSNSETI 627
Query: 189 TVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPP 248
+ G NC A I +S+Q L N+A
Sbjct: 628 IITGKRANCEAARSRI--------------LSIQKDL---ANIAE--------------- 655
Query: 249 SSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETP 308
V+V IPA+ ++IG KG+ I+ + P E
Sbjct: 656 --------------------VEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGS 695
Query: 309 DSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGG 368
S V+I GP KA+ ++ +E K+ IR +IGKGG
Sbjct: 696 GSDT--VVIRGPSSDVEKAKKQLLHLAEE------KQTKSFTVDIRAKPEYHKFLIGKGG 747
Query: 369 KTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDIL 418
+ ++++ T A V+ P ++ DQ ++ IIG A + AQ+++ ++
Sbjct: 748 GKIRKVRDSTGARVIFP---AAEDKDQDLITIIGKEDAVREAQKELEALI 794
Score = 43.1 bits (100), Expect = 5e-04
Identities = 51/211 (24%), Positives = 83/211 (39%), Gaps = 32/211 (15%)
Query: 145 HNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEI 204
H+ FV IGK G L+ +E T TKI I D P I + G E +A E+
Sbjct: 161 HHRFV---IGKNGEKLQDLELKTATKIQIPRPDD-----PSNQIKITGTKEGIEKARHEV 212
Query: 205 MKKVREAYENDVAAMSLQSHLIPGL----NLAAVGLFPASSSAVPPPPSSV-------TG 253
+ E + V + ++ P + N + + + + PP SV TG
Sbjct: 213 LLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTG 272
Query: 254 -----AAPYSSFMQAPEQE-----MVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA 303
A + + E++ + V + +IG KG ++++ S++I
Sbjct: 273 EKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIP 332
Query: 304 PPETPDSKVRMVIITGPPEAQFKAQGRIYGK 334
P DS VI+ G PE +A +Y K
Sbjct: 333 P---SDSISETVILRGEPEKLGQALTEVYAK 360
Score = 42.0 bits (97), Expect = 0.001
Identities = 76/343 (22%), Positives = 138/343 (40%), Gaps = 52/343 (15%)
Query: 105 GTVENCEQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVE 164
GT E E+ E V + EQ ++A E ++ F + G R + ++
Sbjct: 200 GTKEGIEKARHE-------VLLISAEQDKRAVE---RLEVEKAFHPFIAGPYNRLVGEIM 249
Query: 165 QDTETKITISSLQDLTLYNPERT-ITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ- 222
Q+T T+I I + RT I G E +A I KK+ E + ++++
Sbjct: 250 QETGTRINIPPP------SVNRTEIVFTGEKEQLAQAVARI-KKIYEEKKKKTTTIAVEV 302
Query: 223 -----SHLI-PGLNLAAVGLFPASSSAVPPPPSSVT------------GAAPYSSFMQAP 264
++I P N L S PP S++ G A + +A
Sbjct: 303 KKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKAN 362
Query: 265 EQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQ 324
+ V P+ IIGKKGQ++ ++++ + I E D + + GP E
Sbjct: 363 SFTVSSVAAPSWLHRFIIGKKGQNLAKITQ-QMPKVHIEFTEGEDK----ITLEGPTEDV 417
Query: 325 FKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVV 384
AQ +I G +K+ + V+ I + +IGK G +N +++ V +
Sbjct: 418 NVAQEQIEGMVKD--LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRI 471
Query: 385 PRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQK 427
P PD +++I G Q A+R++ ++ ++++ + K
Sbjct: 472 P----PDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTK 510
Score = 35.0 bits (79), Expect = 0.13
Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 13/116 (11%)
Query: 281 IIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG---PPEAQFKAQGRIYGKLKE 337
IIG+KG I Q+ +I+ + + + ITG EA A RI G+L++
Sbjct: 1067 IIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
Query: 338 ENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDEN 393
E+V L+ + R+IG GK + ++ + ++ P+ PD N
Sbjct: 1127 M----VSEDVPLDHRVHA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1172
Score = 34.7 bits (78), Expect = 0.18
Identities = 31/159 (19%), Positives = 64/159 (40%), Gaps = 14/159 (8%)
Query: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQF 325
Q V IP + +IGK G+ ++ L + I+I P+ P ++++ ITG E
Sbjct: 150 QASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIK---ITGTKEGIE 206
Query: 326 KAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVP 385
KA+ + +++ + + V + + G + V E+ T + +P
Sbjct: 207 KARHEVL-------LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIP 259
Query: 386 RDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQ 424
P ++ + G A +I+ I + K++
Sbjct: 260 ----PPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKK 294
Score = 33.5 bits (75), Expect = 0.39
Identities = 24/106 (22%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Query: 315 VIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNEL 374
++++G +A KA+ I +L + + + +P VIGK G+ + +L
Sbjct: 127 IMVSGKLDAVMKARKDIVARL----------QTQASATVAIPKEHHRFVIGKNGEKLQDL 176
Query: 375 QNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQ 420
+ TA ++ +PR P +KI G + A+ ++ I A+
Sbjct: 177 ELKTATKIQIPRPDDPSNQ----IKITGTKEGIEKARHEVLLISAE 218
Score = 30.8 bits (68), Expect = 2.5
Identities = 29/156 (18%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
++V +P +IG+KG I+++ +I + PE ++ ITG +A+
Sbjct: 975 IEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD---IIAITGLAANLDRAK 1031
Query: 329 GRIYGKLKEENFFGPKEEVK-LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRD 387
+ ++KE ++ + + V ++IG+ G + +++ + P D
Sbjct: 1032 AGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFP-D 1090
Query: 388 QTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQ 423
+ Q + I G+ ++ A+ I I+ +++Q
Sbjct: 1091 KDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQ 1126
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,415,841
Number of Sequences: 37866
Number of extensions: 735356
Number of successful extensions: 3015
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 119
Number of HSP's that attempted gapping in prelim test: 2572
Number of HSP's gapped (non-prelim): 423
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.