Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 116063556
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116063556 G-protein coupled receptor 88 [Homo sapiens]
(384 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116063556 G-protein coupled receptor 88 [Homo sapiens] 768 0.0
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 70 3e-12
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 69 7e-12
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 68 2e-11
gi|32261309 G protein-coupled receptor 135 [Homo sapiens] 62 7e-10
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 61 2e-09
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 58 1e-08
gi|5174595 melatonin receptor 1B [Homo sapiens] 55 8e-08
gi|4557865 somatostatin receptor 5 [Homo sapiens] 55 1e-07
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 54 2e-07
gi|149944554 somatostatin receptor 4 [Homo sapiens] 54 3e-07
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 53 5e-07
gi|28875799 cholecystokinin B receptor [Homo sapiens] 52 7e-07
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 52 9e-07
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 51 2e-06
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 51 2e-06
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 51 2e-06
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 51 2e-06
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 50 3e-06
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 50 3e-06
gi|89191863 dopamine receptor D3 isoform e [Homo sapiens] 49 8e-06
gi|9966839 G protein-coupled receptor 84 [Homo sapiens] 49 8e-06
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa... 49 1e-05
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 48 1e-05
gi|5174593 melatonin receptor 1A [Homo sapiens] 48 2e-05
gi|4503383 dopamine receptor D1 [Homo sapiens] 47 3e-05
gi|5921992 adenosine A2a receptor [Homo sapiens] 47 4e-05
gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 46 5e-05
gi|4503907 galanin receptor 3 [Homo sapiens] 46 5e-05
gi|4503905 galanin receptor 2 [Homo sapiens] 46 5e-05
>gi|116063556 G-protein coupled receptor 88 [Homo sapiens]
Length = 384
Score = 768 bits (1982), Expect = 0.0
Identities = 384/384 (100%), Positives = 384/384 (100%)
Query: 1 MTNSSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFR 60
MTNSSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFR
Sbjct: 1 MTNSSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFR 60
Query: 61 KLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLL 120
KLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLL
Sbjct: 61 KLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLL 120
Query: 121 GLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPWA 180
GLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPWA
Sbjct: 121 GLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPPWA 180
Query: 181 PRPGAAPPRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGC 240
PRPGAAPPRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGC
Sbjct: 181 PRPGAAPPRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGC 240
Query: 241 AAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPL 300
AAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPL
Sbjct: 241 AAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPL 300
Query: 301 VWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAA 360
VWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAA
Sbjct: 301 VWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAA 360
Query: 361 AVAATAVPAVSQAQLGTRAAGQHW 384
AVAATAVPAVSQAQLGTRAAGQHW
Sbjct: 361 AVAATAVPAVSQAQLGTRAAGQHW 384
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 70.1 bits (170), Expect = 3e-12
Identities = 111/399 (27%), Positives = 170/399 (42%), Gaps = 67/399 (16%)
Query: 24 EESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCAL 83
E + AG + +++L + +GG L +VI ++ +LQT +N F+ + AADL + L
Sbjct: 36 EAALAGALLALAVLAT---VGGNL---LVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLL 89
Query: 84 WMPQEAVLGLLPTGSAEPPADWD-GAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLI 142
+P A L L TG W GA G L + L +T S+ + C +A++RYL +
Sbjct: 90 VVPPAATLAL--TG------HWPLGATGCE--LWTSVDVLCVTASIETLCALAVDRYLAV 139
Query: 143 TRAPATYQALYQRRHTAGMLALSWAL--ALGLVLLLPPW--------------APRPGAA 186
T P Y AL +R + L W + A+ ++ W PR A
Sbjct: 140 TN-PLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRVGADAEAQRCHSNPRCCAF 198
Query: 187 PPRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAA 246
+ Y L ++ + ++L Y R V+ +++ +L L P + A
Sbjct: 199 ASNMPYVLLSSSVSFYLPLLVMLFVY---ARVFVVATRQLRLLRGELGRFPPEESPPA-- 253
Query: 247 FPGAQHAPGPGGAAHPAQAQPL----PPALHPRRAQRRLSGLSVLL----LCCV-FLLAT 297
P AP P G P + P P L P R R L L +++ LC + F LA
Sbjct: 254 -PSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLAN 312
Query: 298 QPLVWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVL------ 351
V +L +P P A +W L A SA NPL+Y R+ +FR + R +L
Sbjct: 313 ---VLRALGGPSLVPGP-AFLALNW-LGYANSAFNPLIYC-RSPDFRSAFRRLLCRCGRR 366
Query: 352 --PGVGDAAAAAVAATAVPAV----SQAQLGTRAAGQHW 384
P AA A+ + VPA +Q +L R G W
Sbjct: 367 LPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASW 405
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 68.9 bits (167), Expect = 7e-12
Identities = 85/331 (25%), Positives = 137/331 (41%), Gaps = 43/331 (12%)
Query: 49 NGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGA 108
N +VI ++ +LQT +N FI++ +ADL + L +P A + + W+
Sbjct: 76 NVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVW--------GRWE-Y 126
Query: 109 GGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWAL 168
G + L + L +T S+ + C++AL+RYL IT +P YQ+L R G++ WA+
Sbjct: 127 GSFFCELWTSVDVLCVTASIETLCVIALDRYLAIT-SPFRYQSLLTRARARGLVCTVWAI 185
Query: 169 ALGLVLLLP---PWAPRPGAAPPRVH-------------YPALLAAAALLAQTALLLHCY 212
+ LV LP W R + Y + + ++ Y
Sbjct: 186 S-ALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVY 244
Query: 213 LGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPG-PGGAAHPAQAQPLPPA 271
L + R + VK++ L G A + P AP P G PA A P
Sbjct: 245 LRVFREAQKQVKKIDSCERRF---LGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAPL 301
Query: 272 LHPRRAQRRLSGLSVL----------LLCCVFLLATQPLVWVSLASGFSLP-VPWGVQAA 320
+ R +RR S L L ++ VF L P ++ F VP +
Sbjct: 302 ANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFVF 361
Query: 321 SWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
L A SA NP++Y R+ +FR++ + +L
Sbjct: 362 FNWLGYANSAFNPIIYC-RSPDFRKAFQGLL 391
>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
sapiens]
Length = 377
Score = 67.8 bits (164), Expect = 2e-11
Identities = 92/384 (23%), Positives = 150/384 (39%), Gaps = 50/384 (13%)
Query: 3 NSSSTSTSSTTGGSLLLLCEEEESWAGR-----RIPVSLLYSGLAIGGTLANGMVIYLVS 57
N S+ L E E+W R +I ++++ S + + L+N V+ +
Sbjct: 5 NQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTIL 64
Query: 58 SFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRG 117
RKL T +N I + DL V L MP + T W+ ++L
Sbjct: 65 LTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHT--------WNFG----QILCD 112
Query: 118 GLLGLGL---TVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVL 174
L + T S+L C++AL+RY IT A Y H A M+A+ WA++ + +
Sbjct: 113 IWLSSDITCCTASILHLCVIALDRYWAITDA-LEYSKRRTAGHAATMIAIVWAIS--ICI 169
Query: 175 LLPPWAPRPGAA----------PPRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVK 224
+PP R A ++ Y A + LL+ Y I R R +
Sbjct: 170 SIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRIL 229
Query: 225 RVSVL---NFHLLHQLPG------CAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPR 275
L F H + G C+ ++ G H+ G + + + AL +
Sbjct: 230 NPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERK 289
Query: 276 R--AQRRLSGLSVL-LLCCVFLLATQPLVWVSLASGFSLPVPWGVQAA----SWLLCCAL 328
R A R +L ++ F++ P VSL W A +W L
Sbjct: 290 RISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTW-LGYLN 348
Query: 329 SALNPLLYTWRNEEFRRSVRSVLP 352
S +NP++YT NEEFR++ + ++P
Sbjct: 349 SLINPIIYTVFNEEFRQAFQKIVP 372
>gi|32261309 G protein-coupled receptor 135 [Homo sapiens]
Length = 494
Score = 62.4 bits (150), Expect = 7e-10
Identities = 65/208 (31%), Positives = 91/208 (43%), Gaps = 33/208 (15%)
Query: 46 TLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPA-- 103
+L N V+ ++ R+L+T +NAFI++ +DL L +P + P G + P A
Sbjct: 118 SLGNCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAA 177
Query: 104 -DWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGML 162
W G + R G+ VS LS L++L+RY I R P + RR +L
Sbjct: 178 GPWRGFCAASRFF-SSCFGI---VSTLSVALISLDRYCAIVRPP---REKIGRRRALQLL 230
Query: 163 ALSWALALGLVLLLPPW----APRPGAAPPRVH--------YPALLAA--------AALL 202
A +W ALG L PW APR AA H PA L A A L
Sbjct: 231 AGAWLTALGFSL---PWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYL 287
Query: 203 AQTALLLHCYLGIVRRVRVSVKRVSVLN 230
L+ C+ I + VR+S RV +N
Sbjct: 288 LPFLLMCFCHYHICKTVRLSDVRVRPVN 315
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 60.8 bits (146), Expect = 2e-09
Identities = 89/335 (26%), Positives = 140/335 (41%), Gaps = 50/335 (14%)
Query: 41 LAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAE 100
+A+ G L +VI V+ R LQT +N FIVN ADL + A +P A + +L
Sbjct: 109 MAVAGNL---LVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVL------ 159
Query: 101 PPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAG 160
W G ++ + + L T S+LS C ++++RY+ + R Y A+ R A
Sbjct: 160 --GFW-AFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGV-RHSLKYPAIMTERKAAA 215
Query: 161 MLALSWALALGLVLLLPPWAPRPGAAPPRVHYPALLAAAA-----------LLAQTALLL 209
+LAL W +A LV+ + P PP + + A L +++
Sbjct: 216 ILALLWVVA--LVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVM 273
Query: 210 HCYLGIV-----RRVRVSVKRVS------VLNFHLLHQLPGCAAAAAAFPGAQHAPGPGG 258
+C + +V R + VKR VL H C AA GA G
Sbjct: 274 YCRVYVVARSTTRSLEAGVKRERGKASEVVLRIH-------CRGAATGADGAHGMRSAKG 326
Query: 259 AAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWV-SLASGF-SLPVPWG 316
H ++ L R ++ L++++ VF+L P +V L S F L G
Sbjct: 327 --HTFRSSLSVRLLKFSREKKAAKTLAIVV--GVFVLCWFPFFFVLPLGSLFPQLKPSEG 382
Query: 317 VQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
V + L S +NPL+Y + EF+R+ +L
Sbjct: 383 VFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLL 417
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 58.2 bits (139), Expect = 1e-08
Identities = 79/323 (24%), Positives = 135/323 (41%), Gaps = 47/323 (14%)
Query: 48 ANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDG 107
AN ++I L+ + L+ TSN F+V+ +DL V + M PPA +
Sbjct: 43 ANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVM---------------PPAMLNA 87
Query: 108 AGGSYRLLRGGLL------GLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGM 161
G + L RG L + + S+L+ CL++L+RYLLI +P Y+ +
Sbjct: 88 LYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLIL-SPLRYKLRMTPLRALAL 146
Query: 162 LALSWALA--LGLVLLLPPW-------APRPGAAPPRVHYPALLAAAAL--LAQTALLLH 210
+ +W+LA + LL W P PG P +L A+ L + +
Sbjct: 147 VLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICF 206
Query: 211 CYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPP 270
Y I+ R +V+ L G A+ A+ P PG A ++ L
Sbjct: 207 TYCRILLAARKQAVQVASLT-------TGMASQASETLQVPRTPRPG--VESADSRRL-A 256
Query: 271 ALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGFSLPVPWGV-QAASWLLCCALS 329
H R+A + + L++ +L +F + P ++ + G+ +WL C S
Sbjct: 257 TKHSRKALK--ASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCN-S 313
Query: 330 ALNPLLYTWRNEEFRRSVRSVLP 352
+NP++Y +F+R++ LP
Sbjct: 314 TMNPIIYPLFMRDFKRALGRFLP 336
>gi|5174595 melatonin receptor 1B [Homo sapiens]
Length = 362
Score = 55.5 bits (132), Expect = 8e-08
Identities = 74/312 (23%), Positives = 125/312 (40%), Gaps = 51/312 (16%)
Query: 47 LANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWD 106
+ N +VI V RKL+ N F+V+ ADL V + P +L + +D
Sbjct: 56 VGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVA--FYPYPLILVAI---------FYD 104
Query: 107 G--AGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLAL 164
G G + ++GL + S+ + +A+NRY I + A Y +Y+R HT + L
Sbjct: 105 GWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMA-YHRIYRRWHTPLHICL 163
Query: 165 SWALALGLVLLLPPWAPRPGAAPPRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVK 224
W L +V LLP + PR++ + A+ A+++ +L + V
Sbjct: 164 IWLLT--VVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYL 221
Query: 225 RVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGL 284
R+ VL + A P L P+ S L
Sbjct: 222 RIWVLVLQARRK-----------------------AKPESRLCLKPS-------DLRSFL 251
Query: 285 SVLLLCCVFLLATQPLVWVSLA-----SGFSLPVPWGVQAASWLLCCALSALNPLLYTWR 339
++ ++ +F + PL + LA + +P G+ S+LL S LN ++Y
Sbjct: 252 TMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLL 311
Query: 340 NEEFRRSVRSVL 351
N+ FRR + +L
Sbjct: 312 NQNFRREYKRIL 323
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 54.7 bits (130), Expect = 1e-07
Identities = 89/364 (24%), Positives = 150/364 (41%), Gaps = 73/364 (20%)
Query: 4 SSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQ 63
++S+ +++ GG L S R + V +LY + G N +VIY+V F K++
Sbjct: 13 NASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMK 72
Query: 64 TTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLG 123
T +N +I+N AD+ L+M LGL + + W RL+ L G+
Sbjct: 73 TVTNIYILNLAVADV----LYM-----LGLPFLATQNAASFWPFGPVLCRLVM-TLDGVN 122
Query: 124 LTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGML-ALSWALAL--GLVLLLPPWA 180
S+ +++++RYL + ++ A ++R A + A +W L+L L LL+
Sbjct: 123 QFTSVFCLTVMSVDRYLAVVHPLSS--ARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV 180
Query: 181 PRPGAAPPRVHYPALLAAAALLAQTALL---------LHCYLGIVRRVRVSVKRVSVLNF 231
G P L A + TA+L CYL IV +VR + RV
Sbjct: 181 QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRV----- 235
Query: 232 HLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCC 291
GC RR++R+++ + VL++
Sbjct: 236 -------GCVR--------------------------------RRSERKVTRM-VLVVVL 255
Query: 292 VFLLATQPLVWVSLAS-GFSL---PVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSV 347
VF P V++ + +L P G+ +L A S NP+LY + ++ FR+S
Sbjct: 256 VFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSF 315
Query: 348 RSVL 351
+ VL
Sbjct: 316 QKVL 319
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 54.3 bits (129), Expect = 2e-07
Identities = 79/352 (22%), Positives = 134/352 (38%), Gaps = 47/352 (13%)
Query: 31 RIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMP---Q 87
++ + +L + + + TL+N VI V RKL T +N I + DL V L MP
Sbjct: 49 KVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTM 108
Query: 88 EAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPA 147
V G G W + + T S+L C++AL+RY IT A
Sbjct: 109 YTVTGRWTLGQVVCDF-WLSSDITC-----------CTASILHLCVIALDRYWAITDA-V 155
Query: 148 TYQALYQRRHTAGMLALSWALALGLVLLLPPWAPRPGAAPPRVH----------YPALLA 197
Y A + A M+AL W ++ + L PP+ R A V Y
Sbjct: 156 EYSAKRTPKRAAVMIALVWVFSISISL--PPFFWRQAKAEEEVSECVVNTDHILYTVYST 213
Query: 198 AAALLAQTALLLHCYLGIVRRVRVSVKRVS-------VLNFHLLHQLPGCAAAAAAF--- 247
A T LL+ Y I R + + + + L+ PG ++ +
Sbjct: 214 VGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSR 273
Query: 248 -PGAQHAPGPGGAAHPAQAQPLPPALHPRR---AQRRLSGLSVLLLCCVFLLATQPLVWV 303
P G + + + L ++ A+ R + ++ ++ F++ P +
Sbjct: 274 VPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFII 333
Query: 304 SLASGFSLPVPWGVQAA----SWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
SL W A +WL S +NP++YT NE+F+++ ++
Sbjct: 334 SLVMPICKDACWFHLAIFDFFTWLGYLN-SLINPIIYTMSNEDFKQAFHKLI 384
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 53.5 bits (127), Expect = 3e-07
Identities = 81/366 (22%), Positives = 147/366 (40%), Gaps = 79/366 (21%)
Query: 5 SSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQT 64
S+ + SS + + ++ A + + +Y+ + + G + N +VI+++ + K++T
Sbjct: 21 SAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKT 80
Query: 65 TSNAFIVNGCAAD--LSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLL-- 120
+N +++N AD + ++ A L P GS L R L
Sbjct: 81 ATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSV--------------LCRAVLSVD 126
Query: 121 GLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALS-WALALGLVLLLPPW 179
GL + S+ +++++RY+ + A Y+R A ++ L W +L + L + +
Sbjct: 127 GLNMFTSVFCLTVLSVDRYVAVVHPLRA--ATYRRPSVAKLINLGVWLASLLVTLPIAIF 184
Query: 180 AP-RPG----AAPPRVHYPALLAAAALLAQTALLLH---------CYLGIVRRVRVSVKR 225
A RP A + +P +A + T LL CYL IV ++R
Sbjct: 185 ADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMR----- 239
Query: 226 VSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLS 285
A A G Q RR++++++ L
Sbjct: 240 -----------------AVALRAGWQQR---------------------RRSEKKITRL- 260
Query: 286 VLLLCCVFLLATQPLVWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRR 345
VL++ VF+L P V L + F + V S +L A S NP+LY + ++ FRR
Sbjct: 261 VLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRR 320
Query: 346 SVRSVL 351
+ VL
Sbjct: 321 FFQRVL 326
>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
Length = 430
Score = 52.8 bits (125), Expect = 5e-07
Identities = 78/328 (23%), Positives = 125/328 (38%), Gaps = 69/328 (21%)
Query: 47 LANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWD 106
+ N +V ++V R + T +N FI+N +DL V MP V L+ TG W
Sbjct: 59 VGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLI-TG-------WP 110
Query: 107 GAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSW 166
+ ++ G + G+ ++ S+ + +A+ R+ I ++ R +A+ W
Sbjct: 111 FDNATCKM-SGLVQGMSVSASVFTLVAIAVERFRCIVHP---FREKLTLRKALVTIAVIW 166
Query: 167 ALALGLVLLLPPWAPRPGAAPPRVH---------YPALLAAAAL-------LAQTALLLH 210
ALAL L++ P A H YP A + T L H
Sbjct: 167 ALAL---LIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSH 223
Query: 211 CYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPP 270
YL + + V R++ L Q PG P PGG
Sbjct: 224 IYLAPLALIVVMYARIA----RKLCQAPG--------------PAPGGEE---------- 255
Query: 271 ALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSL---------ASGFSLPVPWGVQAAS 321
A PR ++RR + +L++ +F + +W L A L + A
Sbjct: 256 AADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAH 315
Query: 322 WLLCCALSALNPLLYTWRNEEFRRSVRS 349
WL SA NP++Y + NE FRR ++
Sbjct: 316 WLAFFNSSA-NPIIYGYFNENFRRGFQA 342
>gi|28875799 cholecystokinin B receptor [Homo sapiens]
Length = 447
Score = 52.4 bits (124), Expect = 7e-07
Identities = 85/356 (23%), Positives = 136/356 (38%), Gaps = 72/356 (20%)
Query: 41 LAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPT---G 97
+++GG N ++I ++ R+L+T +NAF+++ +DL + MP + L+ T G
Sbjct: 67 MSVGG---NMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFG 123
Query: 98 SAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRH 157
+ A SY L+G+ ++VS LS +AL RY I R P + R H
Sbjct: 124 TVICKA------VSY------LMGVSVSVSTLSLVAIALERYSAICR-PLQARVWQTRSH 170
Query: 158 TAGMLALSWALALGLVLLLPPWAPRPGAAPPRV-----HYPALLAAAALLAQTALLLHCY 212
A ++ +W L+ GL+++ P PRV +P+ LLL
Sbjct: 171 AARVIVATWLLS-GLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFI 229
Query: 213 LGIVRRVRVS-VKRVSVLNFHL---------------------LHQLPGCAAAAAAFP-- 248
G+V V + R L +HQ C A
Sbjct: 230 PGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGED 289
Query: 249 -----------------GAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCC 291
A APGPG + P QA+ L +R R L + VL C
Sbjct: 290 SDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAK----LLAKKRVVRMLLVIVVLFFLC 345
Query: 292 VFLLATQPLVWVSL-ASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRS 346
+L W + G + + LL A + +NPL+Y + + FR++
Sbjct: 346 -WLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQA 400
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 52.0 bits (123), Expect = 9e-07
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 28/196 (14%)
Query: 41 LAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAE 100
+ + G L N VIY R L+T +N FI+N +D + P + T S
Sbjct: 80 VGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAP------VFFTSSLY 133
Query: 101 PPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAG 160
+ G + G L G+ ++L + +AL+RYL+ITR AT+ +RR
Sbjct: 134 KQWLFGETGCEFYAFCGALFGISSMITLTA---IALDRYLVITRPLATFGVASKRRAAFV 190
Query: 161 MLALSWALALGLVLLLPPWAPRPGAAP---------------PRVH-YPALLAAAALLAQ 204
+L + W A L LPP+ P P V Y LL
Sbjct: 191 LLGV-WLYA--LAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLP 247
Query: 205 TALLLHCYLGIVRRVR 220
++++CY+ I R +R
Sbjct: 248 LLIIIYCYIFIFRAIR 263
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 50.8 bits (120), Expect = 2e-06
Identities = 79/333 (23%), Positives = 140/333 (42%), Gaps = 27/333 (8%)
Query: 30 RRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEA 89
+ I + ++ GL + G L N +VI V+ R L + ++ +IVN ADL + + +P A
Sbjct: 25 KAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSA 84
Query: 90 VLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATY 149
+ +L + G + + + L T S++ C+++++RY+ ++ P Y
Sbjct: 85 IFEVL---------GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVS-YPLRY 134
Query: 150 QALYQRRHTAGMLALSWALALGLVLLLPP---W---APRPGAAPPRVHYPALLAAAALLA 203
+ +R G++AL AL LV+ + P W AP P + +A L
Sbjct: 135 PTIVTQRR--GLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSA-LG 191
Query: 204 QTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAP--GPGGAAH 261
L L L + RV V KR S L + ++AP G G A+
Sbjct: 192 SFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251
Query: 262 PAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGF---SLPVPWGVQ 318
+ L R ++ L +++ C F+L P V F P +
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGC--FVLCWLPFFLVMPIGSFFPDFKPSETVFK 309
Query: 319 AASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
W L S +NP++Y ++EF+++ ++VL
Sbjct: 310 IVFW-LGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 50.8 bits (120), Expect = 2e-06
Identities = 79/333 (23%), Positives = 140/333 (42%), Gaps = 27/333 (8%)
Query: 30 RRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEA 89
+ I + ++ GL + G L N +VI V+ R L + ++ +IVN ADL + + +P A
Sbjct: 25 KAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSA 84
Query: 90 VLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATY 149
+ +L + G + + + L T S++ C+++++RY+ ++ P Y
Sbjct: 85 IFEVL---------GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVS-YPLRY 134
Query: 150 QALYQRRHTAGMLALSWALALGLVLLLPP---W---APRPGAAPPRVHYPALLAAAALLA 203
+ +R G++AL AL LV+ + P W AP P + +A L
Sbjct: 135 PTIVTQRR--GLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSA-LG 191
Query: 204 QTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAP--GPGGAAH 261
L L L + RV V KR S L + ++AP G G A+
Sbjct: 192 SFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251
Query: 262 PAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGF---SLPVPWGVQ 318
+ L R ++ L +++ C F+L P V F P +
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGC--FVLCWLPFFLVMPIGSFFPDFKPSETVFK 309
Query: 319 AASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
W L S +NP++Y ++EF+++ ++VL
Sbjct: 310 IVFW-LGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 50.8 bits (120), Expect = 2e-06
Identities = 79/333 (23%), Positives = 140/333 (42%), Gaps = 27/333 (8%)
Query: 30 RRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEA 89
+ I + ++ GL + G L N +VI V+ R L + ++ +IVN ADL + + +P A
Sbjct: 25 KAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSA 84
Query: 90 VLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATY 149
+ +L + G + + + L T S++ C+++++RY+ ++ P Y
Sbjct: 85 IFEVL---------GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVS-YPLRY 134
Query: 150 QALYQRRHTAGMLALSWALALGLVLLLPP---W---APRPGAAPPRVHYPALLAAAALLA 203
+ +R G++AL AL LV+ + P W AP P + +A L
Sbjct: 135 PTIVTQRR--GLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSA-LG 191
Query: 204 QTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAP--GPGGAAH 261
L L L + RV V KR S L + ++AP G G A+
Sbjct: 192 SFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251
Query: 262 PAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGF---SLPVPWGVQ 318
+ L R ++ L +++ C F+L P V F P +
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGC--FVLCWLPFFLVMPIGSFFPDFKPSETVFK 309
Query: 319 AASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
W L S +NP++Y ++EF+++ ++VL
Sbjct: 310 IVFW-LGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 50.8 bits (120), Expect = 2e-06
Identities = 79/333 (23%), Positives = 140/333 (42%), Gaps = 27/333 (8%)
Query: 30 RRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEA 89
+ I + ++ GL + G L N +VI V+ R L + ++ +IVN ADL + + +P A
Sbjct: 25 KAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSA 84
Query: 90 VLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATY 149
+ +L + G + + + L T S++ C+++++RY+ ++ P Y
Sbjct: 85 IFEVL---------GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVS-YPLRY 134
Query: 150 QALYQRRHTAGMLALSWALALGLVLLLPP---W---APRPGAAPPRVHYPALLAAAALLA 203
+ +R G++AL AL LV+ + P W AP P + +A L
Sbjct: 135 PTIVTQRR--GLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSA-LG 191
Query: 204 QTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAP--GPGGAAH 261
L L L + RV V KR S L + ++AP G G A+
Sbjct: 192 SFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251
Query: 262 PAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGF---SLPVPWGVQ 318
+ L R ++ L +++ C F+L P V F P +
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGC--FVLCWLPFFLVMPIGSFFPDFKPSETVFK 309
Query: 319 AASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
W L S +NP++Y ++EF+++ ++VL
Sbjct: 310 IVFW-LGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 50.4 bits (119), Expect = 3e-06
Identities = 95/420 (22%), Positives = 153/420 (36%), Gaps = 86/420 (20%)
Query: 3 NSSSTSTSSTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKL 62
N++S TGG+ + + S+ ++ SLL L L N V+ ++ R L
Sbjct: 11 NTTSPPAPFETGGNTTGISDVTVSY---QVITSLLLGTLIFCAVLGNACVVAAIALERSL 67
Query: 63 QTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGL 122
Q +N I + DL V L +P A+ +L + G L L L
Sbjct: 68 QNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTL---------GQVTCDLFIALDVL 118
Query: 123 GLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSWALALGLVLLLPP---W 179
T S+L C +AL+RY IT P Y R A +++L+W +G ++ +PP W
Sbjct: 119 CCTSSILHLCAIALDRYWAIT-DPIDYVNKRTPRRAAALISLTW--LIGFLISIPPMLGW 175
Query: 180 APRPGAAPPRV-------HYPALLAAAALLAQTALLLHCYLGIVR----RVRVSVKRVSV 228
+ P Y A L+L Y I R R+R +VK+V
Sbjct: 176 RTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEK 235
Query: 229 LNFHLLH-----------------------QLPGCAAAAAAFPGAQHAPGPGGAAH---- 261
H + A A GA G A
Sbjct: 236 TGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEV 295
Query: 262 ------------PAQAQPLP--PALHPRR-------------AQRRLSGLSVLLLCCVFL 294
P++A P P PA R+ A+ R + ++ ++ F+
Sbjct: 296 HRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFI 355
Query: 295 LATQPLVWVSLASGF---SLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
L P V+L F S +P + A L + S LNP++Y + N++F+ + + ++
Sbjct: 356 LCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKII 415
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 50.1 bits (118), Expect = 3e-06
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 16/157 (10%)
Query: 22 EEEESWA-GRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSV 80
+ +E W G I +SL+ + G N +VI ++ F +LQT +N FI + ADL +
Sbjct: 27 QRDEVWVVGMGIVMSLIVLAIVFG----NVLVITAIAKFERLQTVTNYFITSLACADLVM 82
Query: 81 CALWMPQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYL 140
L ++P G+A G + + L +T S+ + C++A++RY
Sbjct: 83 ---------GLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYF 133
Query: 141 LITRAPATYQALYQRRHTAGMLALSWALALGLVLLLP 177
IT +P YQ+L + ++ + W ++ GL LP
Sbjct: 134 AIT-SPFKYQSLLTKNKARVIILMVWIVS-GLTSFLP 168
>gi|89191863 dopamine receptor D3 isoform e [Homo sapiens]
Length = 367
Score = 48.9 bits (115), Expect = 8e-06
Identities = 87/350 (24%), Positives = 128/350 (36%), Gaps = 50/350 (14%)
Query: 35 SLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLL 94
+L Y L + NG+V V R LQTT+N +V+ ADL V L MP V+ L
Sbjct: 33 ALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPW--VVYLE 90
Query: 95 PTGSAEPPADWDGAGGSYRLLRGGLLGLGL---TVSLLSHCLVALNRYLLITRAPATYQ- 150
TG G R+ + L + T S+L+ C ++++RY + P YQ
Sbjct: 91 VTG---------GVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVV-MPVHYQH 140
Query: 151 --ALYQRRHTAGMLALSWALALGLVLLLPPWAPRPG-------AAPPRVHYPALLAAAAL 201
R A M+ W LA + L G + P V Y ++++
Sbjct: 141 GTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLP 200
Query: 202 LAQTALL---LHCYLGIVRRVRVSVKRVSVLN-----------------FHLLHQLPGCA 241
T L+ ++ L RR R+ ++ S N L C
Sbjct: 201 FGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQ 260
Query: 242 AAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLV 301
A PG Q G + L P + Q L ++C + T L
Sbjct: 261 DTALGGPGFQERGGELKREEKTR-NSLMPLREKKATQMVAIVLGAFIVCWLPFFLTHVLN 319
Query: 302 WVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
S P A +W L SALNP++YT N EFR++ +L
Sbjct: 320 THCQTCHVS---PELYSATTW-LGYVNSALNPVIYTTFNIEFRKAFLKIL 365
>gi|9966839 G protein-coupled receptor 84 [Homo sapiens]
Length = 396
Score = 48.9 bits (115), Expect = 8e-06
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 12/139 (8%)
Query: 41 LAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAE 100
+A+ GT+ N + + ++ KL+T N I N ADL C L P L
Sbjct: 30 VAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYL------- 82
Query: 101 PPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAG 160
W G ++ + G LL +VS+L+ CL+AL RYLLI P + ++ +
Sbjct: 83 -HLHW-RTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAH-PKLFPQVFSAKGIVL 139
Query: 161 MLALSWALALGLVLLLPPW 179
L +W +G+ P W
Sbjct: 140 ALVSTW--VVGVASFAPLW 156
>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
sapiens]
Length = 384
Score = 48.5 bits (114), Expect = 1e-05
Identities = 87/354 (24%), Positives = 133/354 (37%), Gaps = 79/354 (22%)
Query: 47 LANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWD 106
L N +V+ ++S + + +VN +DL A ++ + G A PA W
Sbjct: 62 LENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLA--PAQW- 118
Query: 107 GAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSW 166
LR GLL L S S A R+ + R P + G + L W
Sbjct: 119 -------FLREGLLFTALAASTFSLLFTAGERFATMVR-PVAESGATKTSRVYGFIGLCW 170
Query: 167 ALA--LGLVLLLPPWA-----PRPGAAPPRVHYPALLAAAALLAQT-ALLLHCYLGIVRR 218
LA LG++ LL W R + P +L + A A ++ Y I R
Sbjct: 171 LLAALLGMLPLLG-WNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRL 229
Query: 219 VRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLPPALHPRRAQ 278
V+ S Q AP P R+A+
Sbjct: 230 VQAS---------------------------GQKAPRPAAR---------------RKAR 247
Query: 279 RRLSGLSVLLLCCVFLLATQPLVWVSLASGFSLPVPWG---VQAASWLLCCAL--SALNP 333
R L +VL++ FL+ PL + LA F + W ++ W+L A+ SA+NP
Sbjct: 248 RLLK--TVLMILLAFLVCWGPLFGLLLADVFGSNL-WAQEYLRGMDWILALAVLNSAVNP 304
Query: 334 LLYTWRNEEFRRSVRSVL---------PGVGDAAAAAVAATAVPAVSQAQLGTR 378
++Y++R+ E R+V S L G GD A AV A + + + + L R
Sbjct: 305 IIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPR 358
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 48.1 bits (113), Expect = 1e-05
Identities = 74/327 (22%), Positives = 129/327 (39%), Gaps = 48/327 (14%)
Query: 34 VSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGL 93
+ LLYS + + G + N +++ +++ R+L +N I N +D+ +C +P
Sbjct: 63 IVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVP------- 115
Query: 94 LPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALY 153
L A P W GG L+ L + + VS+ + +A++RY+++ +L
Sbjct: 116 LTLAYAFEPRGWVFGGGLCHLV-FFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISL- 173
Query: 154 QRRHTAGMLALSWALALGLVLLLPPWAPRPGAAPPRV----HYPALLAAAALLAQTALLL 209
R +A + WAL+ L L P V + L LLL
Sbjct: 174 --RLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLL 231
Query: 210 HCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQAQPLP 269
YL + + +S RVSV + + +PGC + A
Sbjct: 232 VTYLLPLLVILLSYVRVSVKLRNRV--VPGCVTQSQA----------------------- 266
Query: 270 PALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGFSL----PVPWG-VQAASWLL 324
RA+RR + ++++ VF + PL +L P +G VQ L
Sbjct: 267 ---DWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWL 323
Query: 325 CCALSALNPLLYTWRNEEFRRSVRSVL 351
+ + NP +Y W ++ FR +R +L
Sbjct: 324 AMSSACYNPFIYAWLHDSFREELRKLL 350
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 47.8 bits (112), Expect = 2e-05
Identities = 74/345 (21%), Positives = 132/345 (38%), Gaps = 77/345 (22%)
Query: 26 SWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWM 85
SW + L+++ + L N +VI V +KL+ N F+V+ ADL V A++
Sbjct: 24 SWLASALACVLIFT--IVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADL-VVAIYP 80
Query: 86 PQEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRA 145
++ + G W+ G + + G L+GL + S+ + +A+NRY I +
Sbjct: 81 YPLVLMSIFNNG-------WN-LGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHS 132
Query: 146 PATYQALYQRRHTAGMLALSWALALGLVLLLPPWAPRPGAAPPRVH-----------YPA 194
Y LY +++ + L W L L V LP PR++ Y
Sbjct: 133 -LKYDKLYSSKNSLCYVLLIWLLTLAAV--LPNLRAGTLQYDPRIYSCTFAQSVSSAYTI 189
Query: 195 LLAAAALLAQTALLLHCYLGI---VRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQ 251
+ L +++ CYL I V +VR VK
Sbjct: 190 AVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVK--------------------------- 222
Query: 252 HAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLA----- 306
P + L P Q + +++ ++ +F + PL ++ LA
Sbjct: 223 ----------PDRKPKLKP-------QDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDP 265
Query: 307 SGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
+ +P + AS+ + S LN ++Y N+ FR+ R ++
Sbjct: 266 ASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRII 310
>gi|4503383 dopamine receptor D1 [Homo sapiens]
Length = 446
Score = 47.0 bits (110), Expect = 3e-05
Identities = 83/359 (23%), Positives = 149/359 (41%), Gaps = 74/359 (20%)
Query: 31 RIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQT-TSNAFIVNGCAADLSVCALWMPQEA 89
RI + S L + L N +V V FR L++ +N F+++ +DL V L MP +A
Sbjct: 23 RILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKA 82
Query: 90 VLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATY 149
V AE W GS+ + + T S+L+ C+++++RY I+ +P Y
Sbjct: 83 V--------AEIAGFW--PFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAIS-SPFRY 131
Query: 150 QALYQRRHTAGMLALSWALALGLVLLLP---------PWAPRPGAAPPRVH--------- 191
+ + +++++W L++ L+ +P P +P G A
Sbjct: 132 ERKMTPKAAFILISVAWTLSV-LISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSL 190
Query: 192 ---YPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFP 248
Y + + A+++ Y I R + ++R++ L AA
Sbjct: 191 SRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALE-----------RAAVHAK 239
Query: 249 GAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRLSGLSVLL---LCC---VFLL------- 295
Q G G +Q + + +R + L LSV++ +CC F+L
Sbjct: 240 NCQTTTGNGKPVECSQPES-SFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFC 298
Query: 296 ---ATQPLVWVSLASGFSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSVL 351
TQP S + F + V +G W A S+LNP++Y + N +FR++ ++L
Sbjct: 299 GSGETQPFCIDS--NTFDVFVWFG-----W----ANSSLNPIIYAF-NADFRKAFSTLL 345
>gi|5921992 adenosine A2a receptor [Homo sapiens]
Length = 412
Score = 46.6 bits (109), Expect = 4e-05
Identities = 83/351 (23%), Positives = 132/351 (37%), Gaps = 88/351 (25%)
Query: 32 IPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVL 91
I V L + LAI L N +V + V LQ +N F+V+ AAD++V L +P +
Sbjct: 10 ITVELAIAVLAI---LGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITI 66
Query: 92 GLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLT-VSLLSHCLVALNRYLLITRAPATYQ 150
TG + L L LT S+ S +A++RY+ I R P Y
Sbjct: 67 S---TGF---------CAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAI-RIPLRYN 113
Query: 151 ALYQRRHTAGMLALSWAL--ALGLVLLLPPW----APRPGA-----------------AP 187
L G++A+ W L A+GL +L W P+ G
Sbjct: 114 GLVTGTRAKGIIAICWVLSFAIGLTPML-GWNNCGQPKEGKNHSQGCGEGQVACLFEDVV 172
Query: 188 PRVHYPALLAAAALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAF 247
P + A +L L+L YL I R +K++
Sbjct: 173 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQM--------------------- 211
Query: 248 PGAQHAPGPGGAAHPAQAQPLPPALHPRRAQRRL-SGLSVLLLCCVFLLATQPLVWVSLA 306
++QPLP Q+ + + S+ ++ +F L PL +
Sbjct: 212 ----------------ESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPL---HII 252
Query: 307 SGFSLPVPWGVQAASWLLCCAL------SALNPLLYTWRNEEFRRSVRSVL 351
+ F+ P A WL+ A+ S +NP +Y +R EFR++ R ++
Sbjct: 253 NCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKII 303
>gi|150170722 G protein-coupled receptor 50 [Homo sapiens]
Length = 617
Score = 46.2 bits (108), Expect = 5e-05
Identities = 34/128 (26%), Positives = 63/128 (49%), Gaps = 10/128 (7%)
Query: 47 LANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPTGSAEPPADWD 106
+ N MVI V+ +KL+ + N F+V+ AD+ V P +L + G WD
Sbjct: 44 IGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAI--YPYPLMLHAMSIGG------WD 95
Query: 107 GAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQRRHTAGMLALSW 166
+ +++ G + GL + S+ + +A+NRY I + Y+ ++ R+T L ++W
Sbjct: 96 LSQLQCQMV-GFITGLSVVGSIFNIVAIAINRYCYICHS-LQYERIFSVRNTCIYLVITW 153
Query: 167 ALALGLVL 174
+ + VL
Sbjct: 154 IMTVLAVL 161
>gi|4503907 galanin receptor 3 [Homo sapiens]
Length = 368
Score = 46.2 bits (108), Expect = 5e-05
Identities = 79/333 (23%), Positives = 133/333 (39%), Gaps = 55/333 (16%)
Query: 32 IPVSLLYSGLAIGGTLANGMVIYLV-----SSFRKLQTTSNAFIVNGCAADLSVCALWMP 86
+ V ++++ + + GT+ NG+V+ ++ S++++ +T++ FI+N ADL +P
Sbjct: 18 VAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVP 77
Query: 87 QEAVLGLLPTGSAEPPADWDGAGGSYRLLRGGLLGLGLTVSLLSHCLVALNRYLLITRAP 146
+A + L W + + L+ L + S + V+++RYL + R P
Sbjct: 78 FQATIYTLDA--------WLFGALVCKAVH-LLIYLTMYASSFTLAAVSVDRYLAV-RHP 127
Query: 147 ATYQALYQRRHTAGMLALSWALALGLVLLLPPWAPRPGAAPPRVHYPALLAAAALLAQTA 206
+AL R+ + L W LA L P+ G V Y AL
Sbjct: 128 LRSRALRTPRNARAAVGLVWLLA---ALFSAPYLSYYGT----VRYGAL----------E 170
Query: 207 LLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAA---AFPGAQHAPGPGGAAHPA 263
L + + RR + V F + LP + A A GP GAA
Sbjct: 171 LCVPAWEDARRRA------LDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAA--- 221
Query: 264 QAQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQP---LVWVSLASGFSL-PVPWGVQA 319
A RR +G ++L + ++ L P L+ F+ P + +
Sbjct: 222 -------AAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRL 274
Query: 320 ASWLLCCALSALNPLLYTWRNEEFRRSVRSVLP 352
AS L A S LNPL+Y + FR R + P
Sbjct: 275 ASHCLAYANSCLNPLVYALASRHFRARFRRLWP 307
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 46.2 bits (108), Expect = 5e-05
Identities = 75/334 (22%), Positives = 132/334 (39%), Gaps = 50/334 (14%)
Query: 27 WAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMP 86
W + V LL++ + + GT+ N +V+ ++ + +T+N FI+N ADL +P
Sbjct: 21 WHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVP 80
Query: 87 QEAVLGLLPTGSAEPPADWDGAGGSYRLLRG--GLLGLGLTVSLLSHCLVALNRYLLITR 144
+A + L DG L + L+ L + S + V+L+RYL I R
Sbjct: 81 FQATIYTL-----------DGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAI-R 128
Query: 145 APATYQALYQRRHTAGMLALSWALALGLVLLLPPWAPRPGAAPPRVHYPALLAAAALLAQ 204
P + L R+ + L W L+L + + A V +PA A
Sbjct: 129 YPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMD 188
Query: 205 TALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPGAQHAPGPGGAAHPAQ 264
+ YL V + ++ R L L AA GA
Sbjct: 189 ICTFVFSYLLPVLVLGLTYART-------LRYLWRAVDPVAAGSGA-------------- 227
Query: 265 AQPLPPALHPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGFS----LPVPWGVQAA 320
RRA+R+++ + +L++ +F L P + L F + ++
Sbjct: 228 ----------RRAKRKVTRM-ILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRIL 276
Query: 321 SWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGV 354
S L+ A S +NP++Y ++ FR+ R++ G+
Sbjct: 277 SHLVSYANSCVNPIVYALVSKHFRKGFRTICAGL 310
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,158,819
Number of Sequences: 37866
Number of extensions: 795932
Number of successful extensions: 6382
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 147
Number of HSP's that attempted gapping in prelim test: 5963
Number of HSP's gapped (non-prelim): 524
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.