Guide to the Human Genome
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Search of human proteins with 23308693

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23308693 zinc finger and BTB domain containing 9 [Homo
sapiens]
         (473 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens]    986   0.0  
gi|223890203 zinc finger and BTB domain containing 22 [Homo sapi...   233   3e-61
gi|223890199 zinc finger and BTB domain containing 22 [Homo sapi...   233   3e-61
gi|209413766 zinc finger and BTB domain containing 43 [Homo sapi...   125   8e-29
gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]    125   8e-29
gi|32469509 zinc finger and BTB domain containing 12 [Homo sapiens]   118   1e-26
gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens]   112   6e-25
gi|149944640 zinc finger and BTB domain containing 34 [Homo sapi...   109   5e-24
gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi...   106   4e-23
gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein...   105   1e-22
gi|170650685 zinc finger and BTB domain containing 37 isoform a ...   101   2e-21
gi|14210530 zinc finger and BTB domain containing 37 isoform b [...   101   2e-21
gi|16418383 transcriptional repressor NAC1 [Homo sapiens]              97   2e-20
gi|212286156 zinc finger and BTB domain containing 42 [Homo sapi...    97   2e-20
gi|52694665 zinc finger and BTB domain containing 20 [Homo sapiens]    92   1e-18
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]     88   1e-17
gi|5803229 kaiso [Homo sapiens]                                        86   7e-17
gi|156415988 zinc finger and BTB domain containing 7B [Homo sapi...    82   1e-15
gi|239752951 PREDICTED: similar to kruppel-related zinc finger p...    82   1e-15
gi|239752949 PREDICTED: similar to kruppel-related zinc finger p...    82   1e-15
gi|239752947 PREDICTED: similar to kruppel-related zinc finger p...    82   1e-15
gi|18141299 zinc finger and BTB domain containing 26 [Homo sapiens]    81   2e-15
gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]     80   3e-15
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    80   5e-15
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]      78   2e-14
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]       78   2e-14
gi|139394599 hypermethylated in cancer 2 [Homo sapiens]                77   3e-14
gi|224591419 zinc finger and BTB domain containing 8B [Homo sapi...    77   4e-14
gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]           77   4e-14
gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]           77   4e-14

>gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens]
          Length = 473

 Score =  986 bits (2549), Expect = 0.0
 Identities = 473/473 (100%), Positives = 473/473 (100%)

Query: 1   METPTPLPPVPASPTCNPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELR 60
           METPTPLPPVPASPTCNPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELR
Sbjct: 1   METPTPLPPVPASPTCNPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELR 60

Query: 61  AHKAVLAAASPYFHDKLLLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLL 120
           AHKAVLAAASPYFHDKLLLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLL
Sbjct: 61  AHKAVLAAASPYFHDKLLLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLL 120

Query: 121 VASGLQMWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPV 180
           VASGLQMWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPV
Sbjct: 121 VASGLQMWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPV 180

Query: 181 QSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRV 240
           QSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRV
Sbjct: 181 QSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRV 240

Query: 241 SGVFPRPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSG 300
           SGVFPRPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSG
Sbjct: 241 SGVFPRPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSG 300

Query: 301 TQPGGAKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGP 360
           TQPGGAKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGP
Sbjct: 301 TQPGGAKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGP 360

Query: 361 GGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRF 420
           GGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRF
Sbjct: 361 GGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRF 420

Query: 421 KLKHHLTEHMKTHAGALHACPHCGRRFRVHACFLRHRDLCKGQGWATAHWTYK 473
           KLKHHLTEHMKTHAGALHACPHCGRRFRVHACFLRHRDLCKGQGWATAHWTYK
Sbjct: 421 KLKHHLTEHMKTHAGALHACPHCGRRFRVHACFLRHRDLCKGQGWATAHWTYK 473


>gi|223890203 zinc finger and BTB domain containing 22 [Homo
           sapiens]
          Length = 634

 Score =  233 bits (594), Expect = 3e-61
 Identities = 194/567 (34%), Positives = 256/567 (45%), Gaps = 125/567 (22%)

Query: 4   PTPLPPVPASPTCNPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHK 63
           P PL   P  P   PA   + + FP+ +S+LLESLN+ RL+G+ CDVS+ VQGRE RAH+
Sbjct: 14  PLPLSLAPP-PLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHR 72

Query: 64  AVLAAASPYFHDKLLLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVAS 123
           AVLAA+SPYFHD++LL     ++LPSV++  AFE +L   Y+GRL +    +   L V S
Sbjct: 73  AVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGS 132

Query: 124 GLQMWQVVDQCSEILRELETS----------------GGGI-SARGGNSYHALLSTTSST 166
            LQMW +VD+C+E+LRE   S                G G+ S  GG    A + +  S 
Sbjct: 133 VLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSH 192

Query: 167 GGWCIRSSPFQTPVQSS----------ASTESPASTESPVG-GEGSELGEVLQIQVEE-- 213
                R+S  Q+P  S+          +S+   A   S VG GE    G V    V    
Sbjct: 193 AS--SRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSG 250

Query: 214 ---------EEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPMTATPRK--- 261
                    E +E  DD  + +G+           V G   R   P   P +  P+K   
Sbjct: 251 GATSGKLLLEADELCDDGGDGRGAV----------VPGAGLR--RPTYTPPSIMPQKHWV 298

Query: 262 -LPEGESAPLELPAPPALPPKIFYIKQEPF------EPKEEISGSGTQP-GGAKEETKVF 313
            +  G + P   P  P  P      ++E        +  EE+ GS   P GG  E T   
Sbjct: 299 YVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSI 358

Query: 314 SG------------------------GDTEGNGELGFLLPSGPGPTSGGGGPSWK----- 344
           S                         G  EG G +  L  SG GPT     PS       
Sbjct: 359 SDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSG-GPTPSSYAPSHPPRPLL 417

Query: 345 PVDLHGNEIL--------SGGGGPG--GAGQAVHGPVKLGGT--------------PPAD 380
           P+D+ GN+IL        S    PG     QA HG V +GGT              P   
Sbjct: 418 PLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGT 477

Query: 381 G-----KRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAG 435
           G     K F C CGK F+ K  RDRH+ +  +LRPF C +CNK+FK+KHHLTEHMKTH G
Sbjct: 478 GSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTG 537

Query: 436 AL-HACPHCGRRFRVHACFLRHRDLCK 461
              + C  C ++F     F+RHR  C+
Sbjct: 538 LKPYECGVCAKKFMWRDSFMRHRGHCE 564


>gi|223890199 zinc finger and BTB domain containing 22 [Homo
           sapiens]
          Length = 634

 Score =  233 bits (594), Expect = 3e-61
 Identities = 194/567 (34%), Positives = 256/567 (45%), Gaps = 125/567 (22%)

Query: 4   PTPLPPVPASPTCNPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHK 63
           P PL   P  P   PA   + + FP+ +S+LLESLN+ RL+G+ CDVS+ VQGRE RAH+
Sbjct: 14  PLPLSLAPP-PLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHR 72

Query: 64  AVLAAASPYFHDKLLLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVAS 123
           AVLAA+SPYFHD++LL     ++LPSV++  AFE +L   Y+GRL +    +   L V S
Sbjct: 73  AVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGS 132

Query: 124 GLQMWQVVDQCSEILRELETS----------------GGGI-SARGGNSYHALLSTTSST 166
            LQMW +VD+C+E+LRE   S                G G+ S  GG    A + +  S 
Sbjct: 133 VLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSH 192

Query: 167 GGWCIRSSPFQTPVQSS----------ASTESPASTESPVG-GEGSELGEVLQIQVEE-- 213
                R+S  Q+P  S+          +S+   A   S VG GE    G V    V    
Sbjct: 193 AS--SRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSG 250

Query: 214 ---------EEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPMTATPRK--- 261
                    E +E  DD  + +G+           V G   R   P   P +  P+K   
Sbjct: 251 GATSGKLLLEADELCDDGGDGRGAV----------VPGAGLR--RPTYTPPSIMPQKHWV 298

Query: 262 -LPEGESAPLELPAPPALPPKIFYIKQEPF------EPKEEISGSGTQP-GGAKEETKVF 313
            +  G + P   P  P  P      ++E        +  EE+ GS   P GG  E T   
Sbjct: 299 YVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSI 358

Query: 314 SG------------------------GDTEGNGELGFLLPSGPGPTSGGGGPSWK----- 344
           S                         G  EG G +  L  SG GPT     PS       
Sbjct: 359 SDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSG-GPTPSSYAPSHPPRPLL 417

Query: 345 PVDLHGNEIL--------SGGGGPG--GAGQAVHGPVKLGGT--------------PPAD 380
           P+D+ GN+IL        S    PG     QA HG V +GGT              P   
Sbjct: 418 PLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGT 477

Query: 381 G-----KRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAG 435
           G     K F C CGK F+ K  RDRH+ +  +LRPF C +CNK+FK+KHHLTEHMKTH G
Sbjct: 478 GSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTG 537

Query: 436 AL-HACPHCGRRFRVHACFLRHRDLCK 461
              + C  C ++F     F+RHR  C+
Sbjct: 538 LKPYECGVCAKKFMWRDSFMRHRGHCE 564


>gi|209413766 zinc finger and BTB domain containing 43 [Homo
           sapiens]
          Length = 467

 Score =  125 bits (314), Expect = 8e-29
 Identities = 59/121 (48%), Positives = 86/121 (71%)

Query: 18  PAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKL 77
           P   + ++EFP  SS++L+ LN+ R +G+ CDVS++VQG   RAHKAVLAA+SPYF D++
Sbjct: 3   PGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQV 62

Query: 78  LLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEI 137
           LL ++ R+ LP V+    FE +L   Y+GRL +P   + ++L  AS LQMW VVD+C+E+
Sbjct: 63  LLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEV 122

Query: 138 L 138
           L
Sbjct: 123 L 123



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 39/83 (46%), Positives = 49/83 (59%), Gaps = 1/83 (1%)

Query: 379 ADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL- 437
           A  K + C CGK F  K +RDRH+ +   LRP+GCG+C K+FK+KHHL  HMK H G   
Sbjct: 368 ATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTGIKP 427

Query: 438 HACPHCGRRFRVHACFLRHRDLC 460
           + C  C +RF     F RH   C
Sbjct: 428 YECNICAKRFMWRDSFHRHVTSC 450


>gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]
          Length = 467

 Score =  125 bits (314), Expect = 8e-29
 Identities = 59/121 (48%), Positives = 86/121 (71%)

Query: 18  PAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKL 77
           P   + ++EFP  SS++L+ LN+ R +G+ CDVS++VQG   RAHKAVLAA+SPYF D++
Sbjct: 3   PGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQV 62

Query: 78  LLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEI 137
           LL ++ R+ LP V+    FE +L   Y+GRL +P   + ++L  AS LQMW VVD+C+E+
Sbjct: 63  LLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEV 122

Query: 138 L 138
           L
Sbjct: 123 L 123



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 39/83 (46%), Positives = 49/83 (59%), Gaps = 1/83 (1%)

Query: 379 ADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL- 437
           A  K + C CGK F  K +RDRH+ +   LRP+GCG+C K+FK+KHHL  HMK H G   
Sbjct: 368 ATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTGIKP 427

Query: 438 HACPHCGRRFRVHACFLRHRDLC 460
           + C  C +RF     F RH   C
Sbjct: 428 YECNICAKRFMWRDSFHRHVTSC 450


>gi|32469509 zinc finger and BTB domain containing 12 [Homo sapiens]
          Length = 459

 Score =  118 bits (295), Expect = 1e-26
 Identities = 122/450 (27%), Positives = 184/450 (40%), Gaps = 40/450 (8%)

Query: 23  IQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDA 82
           ++ + P H ++ L ++N+ R E +FCDV+++    + R HK +LAA SP+  D+ LL  +
Sbjct: 8   LRFQLPGHEAATLRNMNQLRAEERFCDVTIVADSLKFRGHKVILAACSPFLRDQFLLNPS 67

Query: 83  PRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRELE 142
             L +  +  A     LL   Y+G L   +  +  +L  AS LQM  VV++C   L +  
Sbjct: 68  SELQVSLMHSARIVADLLLSCYTGALEFAVRDIVNYLTAASYLQMEHVVEKCRNALSQFI 127

Query: 143 TSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSASTESPASTESPVGGEGSE 202
               G+    G S  +L+S+ S+T        P +TP    A    P     P      +
Sbjct: 128 EPKIGLK-EDGVSEASLVSSISATKSLL---PPARTP--KPAPKPPPPPPLPPPLLRPVK 181

Query: 203 LGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPMTATPRKL 262
           L   L   +E + EEE++D+DED     + +      V+     P G             
Sbjct: 182 LEFPLDEDLELKAEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGLGGGLGIGGSVGG 241

Query: 263 PEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSGTQ--PGGAKEETKVFSGGDTEG 320
             GE A   +P     PP+   + +  +   E+  G G    PGG        S G T G
Sbjct: 242 HLGELAQSSVPPSTVAPPQ--GVVKACYSLSEDAEGEGLLLIPGGRA------SVGATSG 293

Query: 321 NGELG--FLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGPGG----------AGQAVH 368
             E     +   G G + G GG S  P+          GG  GG            +   
Sbjct: 294 LVEAAAVAMAARGAGGSLGAGG-SRGPLP---------GGFSGGNPLKNIKCTKCPEVFQ 343

Query: 369 GPVKLGGTPPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLT 427
           G  KL     A    F C  CGK+F      +RH+ +   ++   CGIC K F  K  L 
Sbjct: 344 GVEKLVFHMRAQHFIFMCPRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLH 403

Query: 428 EHMKTHAGAL-HACPHCGRRFRVHACFLRH 456
           +H+  H+GA  + C +C  RF       RH
Sbjct: 404 DHLNLHSGARPYRCSYCDVRFAHKPAIRRH 433


>gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens]
          Length = 511

 Score =  112 bits (281), Expect = 6e-25
 Identities = 124/474 (26%), Positives = 179/474 (37%), Gaps = 66/474 (13%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPR 84
           I     S SLLE+LN  RL G FCDV++ ++   LRAH+ VLAA SP+F DKLLLG +  
Sbjct: 10  IHLQNFSRSLLETLNGQRLGGHFCDVTVRIREASLRAHRCVLAAGSPFFQDKLLLGHS-E 68

Query: 85  LTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRELETS 144
           + +P V+ A     L++ +YSG L +        L  AS L++  V+D+C++I+      
Sbjct: 69  IRVPPVVPAQTVRQLVEFLYSGSLVVAQGEALQVLTAASVLRIQTVIDECTQIIARARAP 128

Query: 145 GGG-------------ISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQ-SSASTESPA 190
           G                 A+  +    LL+           S   + P +    +  +PA
Sbjct: 129 GTSAPTPLPTPVPPPLAPAQLRHRLRHLLAARPPGHPGAAHSRKQRQPARLQLPAPPTPA 188

Query: 191 STESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGP 250
             E P       L      + +E++EE +D+ D + G              G       P
Sbjct: 189 KAEGP--DADPSLSAAPDDRGDEDDEESDDETDGEDGE------------GGGPGEGQAP 234

Query: 251 HPLPMTATPRKLPEGESAPLELPAPPALPP-----KIFYI---KQEPFEPKEEIS----G 298
              P  A        +SA  E PAP  L       + F       E   P   +S     
Sbjct: 235 PSFPDCAAGFLTAAADSACEEPPAPTGLADYSGAGRDFLRGAGSAEDVFPDSYVSTWHDE 294

Query: 299 SGTQPGGAKEETKVFSGGDTEGNGELGFLLPSGP---------------GPTSGGGGPSW 343
            G  P G   ET V       G+   G   P  P                P S   GP+ 
Sbjct: 295 DGAVPEGCPTETPVQPDCILSGSRPPGVKTPGPPVALFPFHLGAPGPPAPPPSAPSGPAP 354

Query: 344 KP-----VDLHGNEILSGGGGPGGAGQAVHGPVKLG---GTPPADGKRFGCL-CGKRFAV 394
            P       L      S   G   A  A       G    TP A+   + C  C K F+ 
Sbjct: 355 APPPAFYPTLQPEAAPSTQLGEVPAPSAAPTTAPSGTPARTPGAEPPTYECSHCRKTFSS 414

Query: 395 KPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGA-LHACPHCGRRF 447
           +    +H+ +    +P  C +C + F L+ +L +HM TH G     C  C +RF
Sbjct: 415 RKNYTKHMFIHSGEKPHQCAVCWRSFSLRDYLLKHMVTHTGVRAFQCAVCAKRF 468



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 24/70 (34%), Positives = 36/70 (51%)

Query: 387 LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGALHACPHCGRR 446
           +C + F+++    +H++    +R F C +C KRF  K  L  HM+TH      CP CG+ 
Sbjct: 435 VCWRSFSLRDYLLKHMVTHTGVRAFQCAVCAKRFTQKSSLNVHMRTHRPERAPCPACGKV 494

Query: 447 FRVHACFLRH 456
           F   A   RH
Sbjct: 495 FSHRALLERH 504


>gi|149944640 zinc finger and BTB domain containing 34 [Homo
           sapiens]
          Length = 500

 Score =  109 bits (273), Expect = 5e-24
 Identities = 120/457 (26%), Positives = 189/457 (41%), Gaps = 54/457 (11%)

Query: 23  IQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDA 82
           IQ + P++SS++L  LN  RL+GK CD+ + +QG+  RAHKAVLAA+SPYF D   L   
Sbjct: 7   IQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTM 66

Query: 83  PRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRELE 142
             L++  +   + FE LL   Y+GR+ L L  + + L  AS LQM  V+D+C++I   LE
Sbjct: 67  SGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQI---LE 123

Query: 143 TSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSAS--TESPASTESPVGGEG 200
           +    IS    +S          +      SS F  PV+ S    ++    T S      
Sbjct: 124 SIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTASSDLRME 183

Query: 201 SELGEVLQIQVEEE------------EEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPH 248
           +   + L+ +++EE            E E + + D +QG   + ++ Q   V     +  
Sbjct: 184 TTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRES-QITEVKVKMEKSD 242

Query: 249 GPH-----PLPMTATPRKLPEGESA-PLELPAPPALPPKIFYIKQEPFEPKE--EISGSG 300
            P       L       ++ +GE    + + +  ++    +   Q   +P    E  GS 
Sbjct: 243 RPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVSEAFGSL 302

Query: 301 TQPGGAKEETKVFSGG--------------DTEG--NGELGFLLPSGPG----PTSGGGG 340
           +    ++     F GG              D +G   G     + + PG    P      
Sbjct: 303 SNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSPRERSAR 362

Query: 341 PSWKPVDLHGNEILSGGGGPGGAGQAVHGPVKLGGTPPADGKRFGC-LCGKRFAVKPKRD 399
             W P +     I  G           H  + +G TP      F C  CGK++  K + +
Sbjct: 363 GHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITP------FVCKFCGKKYTRKDQLE 416

Query: 400 RHIMLTFSLRPFGCGICNKRFKLKHHLTEHM-KTHAG 435
            HI      +PF C IC K F  +  L +H+ K H G
Sbjct: 417 YHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPG 453



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 2/77 (2%)

Query: 382 KRFGCL-CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHA-GALHA 439
           +R  C+ CGK F  K   DRH+ L   + PF C  C K++  K  L  H++ H       
Sbjct: 370 ERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFR 429

Query: 440 CPHCGRRFRVHACFLRH 456
           C  CG+ F       +H
Sbjct: 430 CEICGKCFPFQGTLNQH 446


>gi|167234429 zinc finger and BTB domain containing 17 [Homo
           sapiens]
          Length = 803

 Score =  106 bits (265), Expect = 4e-23
 Identities = 124/462 (26%), Positives = 181/462 (39%), Gaps = 70/462 (15%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPR 84
           ++FPQHS  +LE LN+ R  G  CD + +V G   +AHKAVLAA S YF  K+L  D   
Sbjct: 1   MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYF--KMLFVDQKD 58

Query: 85  LTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEI--LRELE 142
           +    +  A     +L+ +Y+ +L L  + +   L VA+ LQM  ++  C  +  L E  
Sbjct: 59  VVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSLAEPA 118

Query: 143 TSGGG----ISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSASTESPASTESPVGG 198
           TS GG    ++  GG+                 + +  +    S+ S    A   +P+G 
Sbjct: 119 TSPGGNAEALATEGGD-----------------KRAKEEKVATSTLSRLEQAGRSTPIGP 161

Query: 199 E---GSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPM 255
                 E G   Q      E+ E+ D   +     L    +P   SG            M
Sbjct: 162 SRDLKEERGGQAQSAASGAEQTEKADAPREPPPVEL----KPDPTSG------------M 205

Query: 256 TATPRKLPEGESAPLELPAPPALPPKIFYIKQE--------PFEPKEEISGSGTQPGGAK 307
            A   +    ES+  E+   PA   +    +QE        P E KEE  GS  + G A 
Sbjct: 206 AAAEAEAALSESSEQEMEVEPARKGEEEQKEQEEQEEEGAGPAEVKEE--GSQLENGEAP 263

Query: 308 EETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILS----GGGGPGGA 363
           EE +      T+   ELG       G  SG  G   +    +G+ I      G       
Sbjct: 264 EENENEESAGTDSGQELG---SEARGLRSGTYGDRTES-KAYGSVIHKCEDCGKEFTHTG 319

Query: 364 GQAVHGPVKLGGTPPADGKRFGCL-CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKL 422
               H  +  G  P      F C  C K F+       H      L+P+GC  C K ++L
Sbjct: 320 NFKRHIRIHTGEKP------FSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRL 373

Query: 423 KHHLTEHMKTHAG-ALHACPHCGRRFRVHACFLRHRDLCKGQ 463
              L  H K H+G A + C  CG+ F       RH+ +  G+
Sbjct: 374 ISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGE 415



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 1/61 (1%)

Query: 388 CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HACPHCGRR 446
           CGKRF    +   HI    ++RP  C +C+K F     L++H+  H G   + C  CGR 
Sbjct: 563 CGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRG 622

Query: 447 F 447
           F
Sbjct: 623 F 623



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 1/61 (1%)

Query: 388 CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTH-AGALHACPHCGRR 446
           CGK F       RH ++    +P+ C  C + F        H++TH     H CPHC ++
Sbjct: 395 CGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKK 454

Query: 447 F 447
           F
Sbjct: 455 F 455



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 382 KRFGCL-CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HA 439
           K + C+ C ++FA      RH+ +    +P  C +C K F     L  H++ H G   + 
Sbjct: 500 KPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYV 559

Query: 440 CPHCGRRF---RVHACFLRHRD 458
           C  CG+RF      A  +RH D
Sbjct: 560 CERCGKRFVQSSQLANHIRHHD 581



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 388 CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HACPHCGRR 446
           C K+F        H+ +  +  P  C  C K+F    +L  H++ H+G   + C HC R+
Sbjct: 451 CDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQ 510

Query: 447 FRVHACFLRHRDLCKGQ 463
           F       RH  +  G+
Sbjct: 511 FADPGALQRHVRIHTGE 527



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 1/79 (1%)

Query: 379 ADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGALH 438
           ADG      CGK+F       RH+ +    +P+ C  C ++F     L  H++ H G   
Sbjct: 470 ADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRHVRIHTGEKP 529

Query: 439 A-CPHCGRRFRVHACFLRH 456
             C  CG+ F   +  + H
Sbjct: 530 CQCVMCGKAFTQASSLIAH 548



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 388 CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTH-AGALHACPHCGRR 446
           CG+ F+    + RH+    + +   C  C+K+F    +L  H+K H A     C  CG++
Sbjct: 423 CGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQ 482

Query: 447 FRVHACFLRHRDLCKGQ 463
           F       RH  +  G+
Sbjct: 483 FTTSGNLKRHLRIHSGE 499



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 1/50 (2%)

Query: 387 LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKT-HAG 435
           +C K F       +HI++    +P+ C  C + F    +L  H+KT H G
Sbjct: 590 VCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQG 639


>gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein)
           [Homo sapiens]
          Length = 480

 Score =  105 bits (261), Expect = 1e-22
 Identities = 118/443 (26%), Positives = 168/443 (37%), Gaps = 55/443 (12%)

Query: 26  EFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDA--- 82
           EF +HSS +L +LN  RL G   DV+LLV G+ LRAHKAVL A S +F+  +  G A   
Sbjct: 16  EFTRHSSDVLGNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFY-SIFRGRAGVG 74

Query: 83  -PRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILREL 141
              L+LP   EA  F  LL  +Y+ RLRL     PA L  A+ LQM  VV  C   + + 
Sbjct: 75  VDVLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQACHRFI-QA 133

Query: 142 ETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSASTESPASTESP------ 195
                GIS R   +      T    G           P +S + ++ P S  SP      
Sbjct: 134 SYEPLGISLRPLEAEPPTPPTAPPPGSPRRSEGHPDPPTESRSCSQGPPSPASPDPKACN 193

Query: 196 --------VGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRP 247
                   +  + S+ G ++  +   +   +      D+ S++ S +       G  P P
Sbjct: 194 WKKYKYIVLNSQASQAGSLVGERSSGQPCPQARLPSGDEASSSSSSSSSSSSEEGPIPGP 253

Query: 248 HGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSGTQPGGAK 307
                       R  P   +   +  AP + P  +           ++ SGS ++     
Sbjct: 254 QS----------RLSPTAATVQFKCGAPASTPYLL-------TSQAQDTSGSPSERARPL 296

Query: 308 EETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAV 367
             ++ FS  + E       +     G  S   G   KP        L           A 
Sbjct: 297 PGSEFFSCQNCEA------VAGCSSGLDSLVPGDEDKPYKCQ----LCRSSFRYKGNLAS 346

Query: 368 HGPVKLGGTPPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHL 426
           H  V  G  P      + C +CG RF        H  +    +P+ C  C  RF    HL
Sbjct: 347 HRTVHTGEKP------YHCSICGARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHL 400

Query: 427 TEHMKTHAGAL-HACPHCGRRFR 448
             H+  H G   + CP CG RFR
Sbjct: 401 RAHVLIHTGEKPYPCPTCGTRFR 423


>gi|170650685 zinc finger and BTB domain containing 37 isoform a
           [Homo sapiens]
          Length = 503

 Score =  101 bits (251), Expect = 2e-21
 Identities = 49/116 (42%), Positives = 76/116 (65%)

Query: 23  IQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDA 82
           IQ+E P  S+S+L  LN+ R++G+ CD+ + VQG+  RAHK VLAA+SPYF D + L + 
Sbjct: 7   IQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEM 66

Query: 83  PRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEIL 138
             +++  +     FE LL   Y+GR+ L L  + ++L  AS LQM  ++D+C++IL
Sbjct: 67  STVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQIL 122



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 383 RFGCL-CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAG--ALHA 439
           R  C+ C K F  K   DRH+ L   + PF C +C K++  K  L  H++ H G    H 
Sbjct: 372 RLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFH- 430

Query: 440 CPHCGRRFRVHACFLRH 456
           C  CG+ F   A   +H
Sbjct: 431 CHVCGKSFPFQAILNQH 447



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)

Query: 368 HGPVKLGGTPPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHL 426
           H  + +G TP      F C +CGK++  K + + HI      +PF C +C K F  +  L
Sbjct: 391 HMRLHMGITP------FVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAIL 444

Query: 427 TEHM-KTHAGAL 437
            +H  K H G +
Sbjct: 445 NQHFRKNHPGCI 456


>gi|14210530 zinc finger and BTB domain containing 37 isoform b
           [Homo sapiens]
          Length = 361

 Score =  101 bits (251), Expect = 2e-21
 Identities = 49/116 (42%), Positives = 76/116 (65%)

Query: 23  IQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDA 82
           IQ+E P  S+S+L  LN+ R++G+ CD+ + VQG+  RAHK VLAA+SPYF D + L + 
Sbjct: 7   IQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEM 66

Query: 83  PRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEIL 138
             +++  +     FE LL   Y+GR+ L L  + ++L  AS LQM  ++D+C++IL
Sbjct: 67  STVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQIL 122


>gi|16418383 transcriptional repressor NAC1 [Homo sapiens]
          Length = 527

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 88/346 (25%), Positives = 147/346 (42%), Gaps = 60/346 (17%)

Query: 21  RTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLG 80
           +T+Q+E P   +S+LE LN  RL+G +CDVS++V+G   +AH+AVLAA+S YF D     
Sbjct: 3   QTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNNS 62

Query: 81  DAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRE 140
            +  + LP+ ++  +F+ +L   Y+GRL + +      +  A  LQ+ +++++ +E    
Sbjct: 63  RSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFF-- 120

Query: 141 LETSGGGISARGGNSYHALLSTTSS----TGGWCIRSSPFQTPVQSSASTESPASTESPV 196
           L+ S     ++G ++  A  S   S    T GW   S+P   P+ S   TE         
Sbjct: 121 LKVSSPSCDSQGLHAEEAPSSEPQSPVAQTSGWPACSTPL--PLVSRVKTEQ-------- 170

Query: 197 GGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPMT 256
             + S+  + + +     +  +++      GS  +++   P   +    RPH P      
Sbjct: 171 --QESDSVQCMPVAKRLWDSGQKEAGGGGNGSRKMAKFSTPDLAAN---RPHQP------ 219

Query: 257 ATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSGTQPGGAKEETKVFSGG 316
                 P  + AP+   A PA+                  +G+G   GG      V SG 
Sbjct: 220 ------PPPQQAPVVAAAQPAV-----------------AAGAGQPAGGVAAAGGVVSGP 256

Query: 317 DTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGPGG 362
            T           + PG +S     S  P   H  E     GG  G
Sbjct: 257 STSER--------TSPGTSSAYTSDS--PGSYHNEEDEEEDGGEEG 292


>gi|212286156 zinc finger and BTB domain containing 42 [Homo
           sapiens]
          Length = 422

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 120/446 (26%), Positives = 161/446 (36%), Gaps = 52/446 (11%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPR 84
           +EFP+H   LL  L + R  G  CD ++LV      AH+AVLAA S YFH  L   D P 
Sbjct: 1   MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFH--LFYRDRPA 58

Query: 85  LTLPSV------IEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEIL 138
            +  +V      + A AF  LL  +Y GRL L    +   L  AS L M+ +V  C   L
Sbjct: 59  GSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRL 118

Query: 139 RELETS-GGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSASTESPASTESPVG 197
           +E + S   G  A G             T   C  +   + P     +   P ++  P  
Sbjct: 119 QEKDRSLDPGNPAPGAEPAQPPCPWPVWTADLCPAARKAKLPPFGVKAALPPRASGPPPC 178

Query: 198 GEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPMTA 257
               E  + L + ++    +E            + QTP   +      R  G  PL    
Sbjct: 179 QVPEESDQALDLSLKSGPRQER------VHPPCVLQTPLCSQ------RQPGAQPLVKDE 226

Query: 258 TPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSGTQP---GGAKEETKVFS 314
                 + ES+    P  P  PP +         P  +    G QP    G         
Sbjct: 227 RDSLSEQEESSSSRSPHSPPKPPPV---------PAAKGLVVGLQPLPLSGEGSRELELG 277

Query: 315 GGDTEGNGELGFLLPSGP---GPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHGPV 371
            G      ELG   P GP    P      PS   + LH    LS       + +A   P 
Sbjct: 278 AGRLASEDELG---PGGPLCICPLCSKLFPSSHVLQLH----LSAHFRERDSTRARLSPD 330

Query: 372 KLGGTPPADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMK 431
            +  T P        LCGK F+      RH       +P+ C  C K F+  H+L+ H  
Sbjct: 331 GVAPTCP--------LCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTV 382

Query: 432 THAGAL-HACPHCGRRFRVHACFLRH 456
            H     HAC  C RRF       RH
Sbjct: 383 VHTREKPHACRWCERRFTQSGDLYRH 408



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 17/64 (26%), Positives = 22/64 (34%), Gaps = 13/64 (20%)

Query: 413 CGICNKRFKLKHHLTEHMKTHA-------------GALHACPHCGRRFRVHACFLRHRDL 459
           C +C+K F   H L  H+  H              G    CP CG+ F       RH   
Sbjct: 296 CPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCGKTFSCTYTLKRHERT 355

Query: 460 CKGQ 463
             G+
Sbjct: 356 HSGE 359


>gi|52694665 zinc finger and BTB domain containing 20 [Homo sapiens]
          Length = 668

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 50/120 (41%), Positives = 73/120 (60%), Gaps = 1/120 (0%)

Query: 21  RTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLG 80
           R   I     S+S+LE+LN  R  G FCDV++ + G  LRAH+ VLAA SP+F DKLLLG
Sbjct: 4   RIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLLG 63

Query: 81  DAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRE 140
            +  + +PSV+   + + L+  +YSG LR+        L  AS LQ+  V+D+C+ I+ +
Sbjct: 64  YSD-IEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQ 122



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 77/353 (21%), Positives = 131/353 (37%), Gaps = 47/353 (13%)

Query: 124 GLQMWQVVD--QCSEILRELETSGGGISARGGNSYHALLSTTSST---------GGWCIR 172
           G Q  Q+++  +  E   + + + G  S   G S+ + +S++  T         G    R
Sbjct: 268 GQQRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAAR 327

Query: 173 SSPFQTPVQSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLS 232
            S  + P Q   + E+PA      GG  +      Q++      E  ++ + D    T+S
Sbjct: 328 DSQAE-PTQPEQAAEAPAE-----GGPQTN-----QLETGASSPERSNEVEMDSTVITVS 376

Query: 233 QTPQPQRVSGVFPRPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEP 292
            +     +           PLP T    +  E  ++ L +P       ++       + P
Sbjct: 377 NSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLP 436

Query: 293 KEEISGSGTQPGGAKEETKVFSGGDTEGNGELGFLLPSGPG-PTSGGGGPSWKPVDLHGN 351
               +   TQP G+  +  +FS        +  F+  S PG  T     P+ +P      
Sbjct: 437 ----ALFTTQPAGSGPKPFLFSLPQPLAGQQTQFVTVSQPGLSTFTAQLPAPQP------ 486

Query: 352 EILSGGGGPGGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPF 411
            + S  G    +GQ    P +              LC K F  K    +H+ +    +P 
Sbjct: 487 -LASSAGHSTASGQGEKKPYEC------------TLCNKTFTAKQNYVKHMFVHTGEKPH 533

Query: 412 GCGICNKRFKLKHHLTEHMKTHAGA-LHACPHCGRRFRVHACFLRHRDLCKGQ 463
            C IC + F LK +L +HM TH G   + C  C +RF   +    H  L +G+
Sbjct: 534 QCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGE 586



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 16/50 (32%), Positives = 25/50 (50%)

Query: 387 LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGA 436
           +C KRF  K   + H+ L    + + C IC K+F  K  L  H+  H+ +
Sbjct: 565 ICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSAS 614


>gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]
          Length = 574

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 124/479 (25%), Positives = 174/479 (36%), Gaps = 67/479 (13%)

Query: 18  PAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKL 77
           P P    +EFP+HS  LL+SL   R +G  CD +++V   +  AH+AVLA+ SP+F    
Sbjct: 44  PFPSWGTMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFY 103

Query: 78  LLGDAPRLTL----PSVIEADAFEGLLQLIYSGRLRLPLDA-LPAHLLVASGLQMWQVVD 132
              +  +  L      ++ A AF  LL  +Y+G+L L  D  +   L  AS L M  +V 
Sbjct: 104 KERELDKRDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVK 163

Query: 133 QCSEIL--RELETSGGGISARGGNSYHALLSTTSST-------------------GGWCI 171
            C   L  R L  +         NS    L   SST                   G W  
Sbjct: 164 VCKRRLQARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKG 223

Query: 172 RSSPFQT-------PVQSSASTESPA-STESPVGGEGSELGEVLQIQVEEEEEEEEDDDD 223
            ++P  T       P+ S A T  P    ++P           + +       E    + 
Sbjct: 224 SAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNY 283

Query: 224 EDQGSATLSQTPQPQRVSG------VFPR-PHGPHP--LPMTATPRKLPEGESAPLELPA 274
              G + +S  P P    G      V P+ P GP     P  + P   P   SAP+   A
Sbjct: 284 FSSGISAVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQA 343

Query: 275 PPALPPKIFYIKQEPFE-PKEEISGSGTQPGGAKEETKVFSGGDTEG---NGELGFLLPS 330
           P     ++  +K E      EE   S  QP G   E    SGG   G   +    F  P 
Sbjct: 344 PAPAEAELVQVKVEAIVISDEETDVSDEQPQG--PERAFPSGGAVYGAQPSQPEAFEDPG 401

Query: 331 GPGPTSGGGGPSWKPVDLH-GNEILSGGG--------GPGGAGQAVHGPVKLGGTPPADG 381
             G    G    + P D H    +L G G         P  A  ++H P+ L     A  
Sbjct: 402 AAGLEEVGPSDHFLPTDPHLPYHLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYEAAP 461

Query: 382 KRFGCL---------CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMK 431
             FG           CGK F+      RH  +    RP+ C  C + +     L  H++
Sbjct: 462 GSFGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520


>gi|5803229 kaiso [Homo sapiens]
          Length = 672

 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 83/299 (27%), Positives = 129/299 (43%), Gaps = 42/299 (14%)

Query: 29  QHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPRLTLP 88
           Q+S SLL SLN  R  G FCDV+++V+ R+ RAHK +L+A+S YFH   L   A ++   
Sbjct: 13  QYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQ--LFSVAGQVVEL 70

Query: 89  SVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRELETSGGGI 148
           S I A+ F  +L  IYS ++      L   L+ +  L   + + +    L ++++  G  
Sbjct: 71  SFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISG-- 128

Query: 149 SARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSASTESPASTES-PVGGEGSELGEVL 207
           +A+ GN+    L   S      I+ S  +   Q + +T  P  TES  +  E  E+ +++
Sbjct: 129 TAQDGNT--EPLPPDSGDKNLVIQKS--KDEAQDNGATIMPIITESFSLSAEDYEMKKII 184

Query: 208 QIQVEEEEEEEEDDDD---------------EDQGSATLSQTPQPQRVSGVFPRPHGPHP 252
                   + ++DDDD                +   A +   P P  +S V P      P
Sbjct: 185 ------VTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSP 238

Query: 253 LPMTATP-RKLP-----------EGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGS 299
                TP +KLP           +G    L   AP  L P I  + Q P      +S S
Sbjct: 239 PLTNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSS 297



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 5/67 (7%)

Query: 171 IRSSPFQTP--VQSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGS 228
           +  +P  TP  V SS     P+S    V  + +    +L      EEEEEE  DD+D   
Sbjct: 283 LNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDD-- 340

Query: 229 ATLSQTP 235
            T+S +P
Sbjct: 341 -TISSSP 346



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 1/62 (1%)

Query: 387 LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAG-ALHACPHCGR 445
           +C + +       RH  +    + + C  C K F L  + T+H   H G   + C  CG+
Sbjct: 498 VCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGK 557

Query: 446 RF 447
            F
Sbjct: 558 SF 559


>gi|156415988 zinc finger and BTB domain containing 7B [Homo
           sapiens]
          Length = 539

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 126/501 (25%), Positives = 170/501 (33%), Gaps = 110/501 (21%)

Query: 17  NPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDK 76
           +P    I I FP HSS LL  LN  R  G  CD+++  QG E R H+AVLAA S YF  K
Sbjct: 3   SPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYF-KK 61

Query: 77  LLL-------------GDAPRLTLPSVIEAD-----AFEGLLQLIYSGRLRLPLDALPAH 118
           L               G A       V E D     A   LL+  Y+  L      +PA 
Sbjct: 62  LFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAV 121

Query: 119 LLVASGLQMWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQT 178
           L  A  L++  V+  C EIL+     G G+ A             S     C R+  +  
Sbjct: 122 LQAARLLEIPCVIAACMEILQ-----GSGLEA------------PSPDEDDCERARQYLE 164

Query: 179 PVQSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQ 238
              ++ ++  P   +SP                                     Q P P 
Sbjct: 165 AFATATASGVPNGEDSP------------------------------------PQVPLPP 188

Query: 239 RVSGVFPRPHGPHPLP-MTATPRKL---PEGESAPLELPAPPALPPKIFYIKQEPFEPKE 294
                 P P  P P+   +  PRK     +G  A   +P  P +P      ++E    + 
Sbjct: 189 ------PPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEEEVAGRV 242

Query: 295 EISGSGTQPGG--------AKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPV 346
             SG G+ PG         A       S    EG  E   L+       + GGGP   P 
Sbjct: 243 GSSG-GSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYPPAYGLAQGGGPPLSPE 301

Query: 347 DLHGNE-------------ILSGGGGPGGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFA 393
           +L  +E             +      PG   Q      KL     +   +   +C K   
Sbjct: 302 ELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQD-----KLVRKRRSQMPQECPVCHKIIH 356

Query: 394 VKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HACPHCGRRFRVHAC 452
              K  RH+      +PF C +C  RF     L  HM+ H G   ++CPHC  RF     
Sbjct: 357 GAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYD 416

Query: 453 FLRHRDLCKGQGWATAHWTYK 473
              H  L  G      H  +K
Sbjct: 417 LKNHMHLHTGDRPYECHLCHK 437



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 97/410 (23%), Positives = 132/410 (32%), Gaps = 84/410 (20%)

Query: 130 VVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSA----- 184
           V+  CS   ++L T GGG +  G         T +   G  +    F  P    A     
Sbjct: 51  VLAACSHYFKKLFTEGGGGAVMGAGGS----GTATGGAGAGVCELDFVGPEALGALLEFA 106

Query: 185 --STESPASTESPVGGEGSEL----------GEVLQIQVEEEEEEEEDDDD------EDQ 226
             +T + +S   P   + + L           E+LQ    E    +EDD +      E  
Sbjct: 107 YTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAF 166

Query: 227 GSATLSQTPQPQRVSGVFPRPHGPHPLPMTAT-----PRKL---PEGESAPLELPAPPAL 278
            +AT S  P  +      P P  P P P         PRK     +G  A   +P  P +
Sbjct: 167 ATATASGVPNGEDSPPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTV 226

Query: 279 PPKIFYIKQEPFEPKEEISGSGTQPGG--------AKEETKVFSGGDTEGNGELGFLLPS 330
           P      ++E    +   SG G+ PG         A       S    EG  E   L+  
Sbjct: 227 PAHPLTYEEEEVAGRVGSSG-GSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYP 285

Query: 331 GPGPTSGGGGPSWKPVDLHGNE-------------ILSGGGGPGGAGQ------------ 365
                + GGGP   P +L  +E             +      PG   Q            
Sbjct: 286 PAYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQDKLVRKRRSQMP 345

Query: 366 --------AVHGPVKLGG--TPPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCG 414
                    +HG  KL          K F C +CG RF    K   H+      RP+ C 
Sbjct: 346 QECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCP 405

Query: 415 ICNKRFKLKHHLTEHMKTHAG-ALHACPHCGRRFRVHACFLRHRDLCKGQ 463
            C  RF   + L  HM  H G   + C  C + F       RH    KGQ
Sbjct: 406 HCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRH---LKGQ 452


>gi|239752951 PREDICTED: similar to kruppel-related zinc finger
           protein hcKrox isoform 3 [Homo sapiens]
          Length = 573

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 126/501 (25%), Positives = 170/501 (33%), Gaps = 110/501 (21%)

Query: 17  NPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDK 76
           +P    I I FP HSS LL  LN  R  G  CD+++  QG E R H+AVLAA S YF  K
Sbjct: 37  SPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYF-KK 95

Query: 77  LLL-------------GDAPRLTLPSVIEAD-----AFEGLLQLIYSGRLRLPLDALPAH 118
           L               G A       V E D     A   LL+  Y+  L      +PA 
Sbjct: 96  LFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAV 155

Query: 119 LLVASGLQMWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQT 178
           L  A  L++  V+  C EIL+     G G+ A             S     C R+  +  
Sbjct: 156 LQAARLLEIPCVIAACMEILQ-----GSGLEA------------PSPDEDDCERARQYLE 198

Query: 179 PVQSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQ 238
              ++ ++  P   +SP                                     Q P P 
Sbjct: 199 AFATATASGVPNGEDSP------------------------------------PQVPLPP 222

Query: 239 RVSGVFPRPHGPHPLP-MTATPRKL---PEGESAPLELPAPPALPPKIFYIKQEPFEPKE 294
                 P P  P P+   +  PRK     +G  A   +P  P +P      ++E    + 
Sbjct: 223 ------PPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEEEVAGRV 276

Query: 295 EISGSGTQPGG--------AKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPV 346
             SG G+ PG         A       S    EG  E   L+       + GGGP   P 
Sbjct: 277 GSSG-GSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYPPAYGLAQGGGPPLSPE 335

Query: 347 DLHGNE-------------ILSGGGGPGGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFA 393
           +L  +E             +      PG   Q      KL     +   +   +C K   
Sbjct: 336 ELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQD-----KLVRKRRSQMPQECPVCHKIIH 390

Query: 394 VKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HACPHCGRRFRVHAC 452
              K  RH+      +PF C +C  RF     L  HM+ H G   ++CPHC  RF     
Sbjct: 391 GAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYD 450

Query: 453 FLRHRDLCKGQGWATAHWTYK 473
              H  L  G      H  +K
Sbjct: 451 LKNHMHLHTGDRPYECHLCHK 471



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 97/410 (23%), Positives = 132/410 (32%), Gaps = 84/410 (20%)

Query: 130 VVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSA----- 184
           V+  CS   ++L T GGG +  G         T +   G  +    F  P    A     
Sbjct: 85  VLAACSHYFKKLFTEGGGGAVMGAGGS----GTATGGAGAGVCELDFVGPEALGALLEFA 140

Query: 185 --STESPASTESPVGGEGSEL----------GEVLQIQVEEEEEEEEDDDD------EDQ 226
             +T + +S   P   + + L           E+LQ    E    +EDD +      E  
Sbjct: 141 YTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAF 200

Query: 227 GSATLSQTPQPQRVSGVFPRPHGPHPLPMTAT-----PRKL---PEGESAPLELPAPPAL 278
            +AT S  P  +      P P  P P P         PRK     +G  A   +P  P +
Sbjct: 201 ATATASGVPNGEDSPPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTV 260

Query: 279 PPKIFYIKQEPFEPKEEISGSGTQPGG--------AKEETKVFSGGDTEGNGELGFLLPS 330
           P      ++E    +   SG G+ PG         A       S    EG  E   L+  
Sbjct: 261 PAHPLTYEEEEVAGRVGSSG-GSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYP 319

Query: 331 GPGPTSGGGGPSWKPVDLHGNE-------------ILSGGGGPGGAGQ------------ 365
                + GGGP   P +L  +E             +      PG   Q            
Sbjct: 320 PAYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQDKLVRKRRSQMP 379

Query: 366 --------AVHGPVKLGG--TPPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCG 414
                    +HG  KL          K F C +CG RF    K   H+      RP+ C 
Sbjct: 380 QECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCP 439

Query: 415 ICNKRFKLKHHLTEHMKTHAG-ALHACPHCGRRFRVHACFLRHRDLCKGQ 463
            C  RF   + L  HM  H G   + C  C + F       RH    KGQ
Sbjct: 440 HCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRH---LKGQ 486


>gi|239752949 PREDICTED: similar to kruppel-related zinc finger
           protein hcKrox isoform 1 [Homo sapiens]
          Length = 539

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 126/501 (25%), Positives = 170/501 (33%), Gaps = 110/501 (21%)

Query: 17  NPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDK 76
           +P    I I FP HSS LL  LN  R  G  CD+++  QG E R H+AVLAA S YF  K
Sbjct: 3   SPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYF-KK 61

Query: 77  LLL-------------GDAPRLTLPSVIEAD-----AFEGLLQLIYSGRLRLPLDALPAH 118
           L               G A       V E D     A   LL+  Y+  L      +PA 
Sbjct: 62  LFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAV 121

Query: 119 LLVASGLQMWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQT 178
           L  A  L++  V+  C EIL+     G G+ A             S     C R+  +  
Sbjct: 122 LQAARLLEIPCVIAACMEILQ-----GSGLEA------------PSPDEDDCERARQYLE 164

Query: 179 PVQSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQ 238
              ++ ++  P   +SP                                     Q P P 
Sbjct: 165 AFATATASGVPNGEDSP------------------------------------PQVPLPP 188

Query: 239 RVSGVFPRPHGPHPLP-MTATPRKL---PEGESAPLELPAPPALPPKIFYIKQEPFEPKE 294
                 P P  P P+   +  PRK     +G  A   +P  P +P      ++E    + 
Sbjct: 189 ------PPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEEEVAGRV 242

Query: 295 EISGSGTQPGG--------AKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPV 346
             SG G+ PG         A       S    EG  E   L+       + GGGP   P 
Sbjct: 243 GSSG-GSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYPPAYGLAQGGGPPLSPE 301

Query: 347 DLHGNE-------------ILSGGGGPGGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFA 393
           +L  +E             +      PG   Q      KL     +   +   +C K   
Sbjct: 302 ELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQD-----KLVRKRRSQMPQECPVCHKIIH 356

Query: 394 VKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HACPHCGRRFRVHAC 452
              K  RH+      +PF C +C  RF     L  HM+ H G   ++CPHC  RF     
Sbjct: 357 GAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYD 416

Query: 453 FLRHRDLCKGQGWATAHWTYK 473
              H  L  G      H  +K
Sbjct: 417 LKNHMHLHTGDRPYECHLCHK 437



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 97/410 (23%), Positives = 132/410 (32%), Gaps = 84/410 (20%)

Query: 130 VVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSA----- 184
           V+  CS   ++L T GGG +  G         T +   G  +    F  P    A     
Sbjct: 51  VLAACSHYFKKLFTEGGGGAVMGAGGS----GTATGGAGAGVCELDFVGPEALGALLEFA 106

Query: 185 --STESPASTESPVGGEGSEL----------GEVLQIQVEEEEEEEEDDDD------EDQ 226
             +T + +S   P   + + L           E+LQ    E    +EDD +      E  
Sbjct: 107 YTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAF 166

Query: 227 GSATLSQTPQPQRVSGVFPRPHGPHPLPMTAT-----PRKL---PEGESAPLELPAPPAL 278
            +AT S  P  +      P P  P P P         PRK     +G  A   +P  P +
Sbjct: 167 ATATASGVPNGEDSPPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTV 226

Query: 279 PPKIFYIKQEPFEPKEEISGSGTQPGG--------AKEETKVFSGGDTEGNGELGFLLPS 330
           P      ++E    +   SG G+ PG         A       S    EG  E   L+  
Sbjct: 227 PAHPLTYEEEEVAGRVGSSG-GSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYP 285

Query: 331 GPGPTSGGGGPSWKPVDLHGNE-------------ILSGGGGPGGAGQ------------ 365
                + GGGP   P +L  +E             +      PG   Q            
Sbjct: 286 PAYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQDKLVRKRRSQMP 345

Query: 366 --------AVHGPVKLGG--TPPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCG 414
                    +HG  KL          K F C +CG RF    K   H+      RP+ C 
Sbjct: 346 QECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCP 405

Query: 415 ICNKRFKLKHHLTEHMKTHAG-ALHACPHCGRRFRVHACFLRHRDLCKGQ 463
            C  RF   + L  HM  H G   + C  C + F       RH    KGQ
Sbjct: 406 HCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRH---LKGQ 452


>gi|239752947 PREDICTED: similar to kruppel-related zinc finger
           protein hcKrox isoform 2 [Homo sapiens]
          Length = 539

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 126/501 (25%), Positives = 170/501 (33%), Gaps = 110/501 (21%)

Query: 17  NPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDK 76
           +P    I I FP HSS LL  LN  R  G  CD+++  QG E R H+AVLAA S YF  K
Sbjct: 3   SPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYF-KK 61

Query: 77  LLL-------------GDAPRLTLPSVIEAD-----AFEGLLQLIYSGRLRLPLDALPAH 118
           L               G A       V E D     A   LL+  Y+  L      +PA 
Sbjct: 62  LFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAV 121

Query: 119 LLVASGLQMWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQT 178
           L  A  L++  V+  C EIL+     G G+ A             S     C R+  +  
Sbjct: 122 LQAARLLEIPCVIAACMEILQ-----GSGLEA------------PSPDEDDCERARQYLE 164

Query: 179 PVQSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQ 238
              ++ ++  P   +SP                                     Q P P 
Sbjct: 165 AFATATASGVPNGEDSP------------------------------------PQVPLPP 188

Query: 239 RVSGVFPRPHGPHPLP-MTATPRKL---PEGESAPLELPAPPALPPKIFYIKQEPFEPKE 294
                 P P  P P+   +  PRK     +G  A   +P  P +P      ++E    + 
Sbjct: 189 ------PPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEEEVAGRV 242

Query: 295 EISGSGTQPGG--------AKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPV 346
             SG G+ PG         A       S    EG  E   L+       + GGGP   P 
Sbjct: 243 GSSG-GSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYPPAYGLAQGGGPPLSPE 301

Query: 347 DLHGNE-------------ILSGGGGPGGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFA 393
           +L  +E             +      PG   Q      KL     +   +   +C K   
Sbjct: 302 ELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQD-----KLVRKRRSQMPQECPVCHKIIH 356

Query: 394 VKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HACPHCGRRFRVHAC 452
              K  RH+      +PF C +C  RF     L  HM+ H G   ++CPHC  RF     
Sbjct: 357 GAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYD 416

Query: 453 FLRHRDLCKGQGWATAHWTYK 473
              H  L  G      H  +K
Sbjct: 417 LKNHMHLHTGDRPYECHLCHK 437



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 97/410 (23%), Positives = 132/410 (32%), Gaps = 84/410 (20%)

Query: 130 VVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSA----- 184
           V+  CS   ++L T GGG +  G         T +   G  +    F  P    A     
Sbjct: 51  VLAACSHYFKKLFTEGGGGAVMGAGGS----GTATGGAGAGVCELDFVGPEALGALLEFA 106

Query: 185 --STESPASTESPVGGEGSEL----------GEVLQIQVEEEEEEEEDDDD------EDQ 226
             +T + +S   P   + + L           E+LQ    E    +EDD +      E  
Sbjct: 107 YTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAF 166

Query: 227 GSATLSQTPQPQRVSGVFPRPHGPHPLPMTAT-----PRKL---PEGESAPLELPAPPAL 278
            +AT S  P  +      P P  P P P         PRK     +G  A   +P  P +
Sbjct: 167 ATATASGVPNGEDSPPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTV 226

Query: 279 PPKIFYIKQEPFEPKEEISGSGTQPGG--------AKEETKVFSGGDTEGNGELGFLLPS 330
           P      ++E    +   SG G+ PG         A       S    EG  E   L+  
Sbjct: 227 PAHPLTYEEEEVAGRVGSSG-GSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYP 285

Query: 331 GPGPTSGGGGPSWKPVDLHGNE-------------ILSGGGGPGGAGQ------------ 365
                + GGGP   P +L  +E             +      PG   Q            
Sbjct: 286 PAYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQDKLVRKRRSQMP 345

Query: 366 --------AVHGPVKLGG--TPPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCG 414
                    +HG  KL          K F C +CG RF    K   H+      RP+ C 
Sbjct: 346 QECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCP 405

Query: 415 ICNKRFKLKHHLTEHMKTHAG-ALHACPHCGRRFRVHACFLRHRDLCKGQ 463
            C  RF   + L  HM  H G   + C  C + F       RH    KGQ
Sbjct: 406 HCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRH---LKGQ 452


>gi|18141299 zinc finger and BTB domain containing 26 [Homo sapiens]
          Length = 441

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 41/116 (35%), Positives = 67/116 (57%)

Query: 23  IQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDA 82
           +  +F  +  S+L+ +N+ R E KFCDV++L+   E++ HK V AA SP+  D+ LL D+
Sbjct: 8   LHFKFENYGDSMLQKMNKLREENKFCDVTVLIDDIEVQGHKIVFAAGSPFLRDQFLLNDS 67

Query: 83  PRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEIL 138
             + +  +  ++    LL   YSG L  P   L  +L  AS LQM  +V++C++ L
Sbjct: 68  REVKISILQSSEVGRQLLLSCYSGVLEFPEMELVNYLTAASFLQMSHIVERCTQAL 123



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 2/77 (2%)

Query: 382 KRFGCL-CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAG-ALHA 439
           K F CL CGK F  K    RH+ +   ++PF C IC K F  K  L +H+  H+G   H 
Sbjct: 296 KLFMCLLCGKTFTQKGNLHRHMRVHAGIKPFQCKICGKTFSQKCSLQDHLNLHSGDKPHK 355

Query: 440 CPHCGRRFRVHACFLRH 456
           C +C   F       +H
Sbjct: 356 CNYCDMVFAHKPVLRKH 372


>gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]
          Length = 584

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 107/462 (23%), Positives = 160/462 (34%), Gaps = 60/462 (12%)

Query: 23  IQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLG-- 80
           I I FP HSS +L  LN  R +G  CDV +LV+GRE   H++VLAA S YF      G  
Sbjct: 9   IGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAV 68

Query: 81  -DAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEIL- 138
            D   +     + A+A   L+   Y+  L +    +   L  A  L++  V   C+++L 
Sbjct: 69  VDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLD 128

Query: 139 RELETSGGGISAR-----------------------GGNSYHALLSTTSSTGGWCIRSSP 175
           R++  +  G  A                          N  ++L    ++       S+ 
Sbjct: 129 RQILAADAGADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMNSLPPAAAAAAASFPWSAF 188

Query: 176 FQTPVQSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTP 235
             +     A+ E+ A+  + V        +        E     D D+ D       +  
Sbjct: 189 GASDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPAERPPTGDGDEGDSNPGLWPERD 248

Query: 236 QPQRVSGVFPRPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEE 295
           +     G+FP P  P          +  E E+A L   AP            EP +    
Sbjct: 249 EDAPTGGLFPPPVAPPAATQNGHYGRGGEEEAASLSEAAP------------EPGDSPGF 296

Query: 296 ISGSGTQPGGAKEETKVFSGGDTEGNGELGFL--LPSGPGPTSGGGGPSWKPVDLHGNEI 353
           +SG+     G         G D +G      L  + S  G      G S +        +
Sbjct: 297 LSGAAEGEDG--------DGPDVDGLAASTLLQQMMSSVGRAGAAAGDSDEESRADDKGV 348

Query: 354 LS------GGGGPGGAGQAVHGPVKLGGTPPADGKRFGC-LCGKRFAVKPKRDRHIMLTF 406
           +        G   G    A    V+      A  K   C +C K      K  RHI    
Sbjct: 349 MDYYLKYFSGAHDGDVYPAWSQKVEKKIRAKAFQK---CPICEKVIQGAGKLPRHIRTHT 405

Query: 407 SLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HACPHCGRRF 447
             +P+ C IC  RF  +  L  HM+ H G   + C  CG  F
Sbjct: 406 GEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAF 447



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 4/85 (4%)

Query: 382 KRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HA 439
           K + C +C  RF  + K   H+      +P+ C  C   F   + L  HM+ H G   + 
Sbjct: 408 KPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQ 467

Query: 440 CPHCGRRFRVHACFLRH--RDLCKG 462
           C  C + F       RH  +D C G
Sbjct: 468 CDSCCKTFVRSDHLHRHLKKDGCNG 492


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 66/228 (28%), Positives = 91/228 (39%), Gaps = 49/228 (21%)

Query: 17  NPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDK 76
           N     I I FP HSS +L SLN  R +G  CDV L+VQ +E R H++VLAA S YF   
Sbjct: 3   NDIDELIGIPFPNHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSVLAACSKYFKKL 62

Query: 77  LLLG---DAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQ 133
              G     P +     ++ +A   +L+  Y+  L +    +   L  A  L++  +V+ 
Sbjct: 63  FTAGTLASQPYVYEIDFVQPEALAAILEFAYTSTLTITAGNVKHILNAARMLEIQCIVNV 122

Query: 134 CSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSASTESPASTE 193
           C EI   +E  G G                                       E     +
Sbjct: 123 CLEI---MEPGGDG-------------------------------------GEEDDKEDD 142

Query: 194 SPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVS 241
                +  E  E      EEEEEEEEDDDD+ +  A     P PQ +S
Sbjct: 143 DDDEDDDDEEDE------EEEEEEEEDDDDDTEDFADQENLPDPQDIS 184



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 54/226 (23%), Positives = 76/226 (33%), Gaps = 35/226 (15%)

Query: 246 RPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSGTQPGG 305
           +P    PL +    RK+ E E   L  P PP  P   F   ++ F            PGG
Sbjct: 273 QPMDSGPLDLVIKNRKIKEEEKEELPPPPPPPFPNDFF---KDMFPDL---------PGG 320

Query: 306 AKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQ 365
                     G  +   + G  L        GG  P W  V+    +  +    P     
Sbjct: 321 PL--------GPIKAENDYGAYLNFLSATHLGGLFPPWPLVEERKLKPKASQQCP----- 367

Query: 366 AVHGPVKLGGTPP------ADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNK 418
             H  +   G  P         K + C +C  RF  + K   H+      RP+ C  CN 
Sbjct: 368 ICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPYLCIHCNA 427

Query: 419 RFKLKHHLTEHMKTHAGAL-HACPHCGRRFRVHACFLRH--RDLCK 461
           +F   + L  HM+ H G   + C  C + F       RH  R  C+
Sbjct: 428 KFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCR 473


>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
          Length = 733

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 138/547 (25%), Positives = 187/547 (34%), Gaps = 132/547 (24%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYF-----HDKLLL 79
           +E P HS  LL  LN  R +G  CDV ++VQ    RAHK VLAA+S Y      HD LL 
Sbjct: 24  MEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLN 83

Query: 80  GDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDA-------------LPAHLLVASGLQ 126
            D        ++    F  +L  IY+GRL    +A             L A L  AS LQ
Sbjct: 84  LD------HDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQ 137

Query: 127 MWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSP-----FQTPV- 180
           +  +V  C    + L+  G     RGG       +     G     ++P     + +PV 
Sbjct: 138 IPDLVALCK---KRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVG 194

Query: 181 -QSSASTESPASTESPVGGEGSEL-----GEVLQIQVEEEEEEEEDDDDEDQGSATLSQT 234
                + E P+  E+ V    +EL     G    +   E         D  + S   S  
Sbjct: 195 PPPPPAAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAA 254

Query: 235 PQ-PQRVSGVFPRPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPK 293
           P+ P     + PRP      P +A P    E    PL LP+ P LP +       P +P 
Sbjct: 255 PERPLAERELPPRPDS----PPSAGPAAYKE---PPLALPSLPPLPFQKLEEAAPPSDPF 307

Query: 294 EEISGS-GTQPGG-----------AKEETKVFSGGD------------TEGNGELGFLLP 329
              SGS G +P G            K E  + S GD             E  G    + P
Sbjct: 308 RGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAVSP 367

Query: 330 SGP---------------GPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHGPVKLG 374
            GP               GP +GG G  +K               PGG  +    P    
Sbjct: 368 GGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGS-SEDPSPPGGHLEGYPCPHLAY 426

Query: 375 GTPPADGKR-FGCL-CGKRFAVKPKRDRHIMLTFSLR---------------------PF 411
           G P + G   + C+ CGK F    + + H+                            PF
Sbjct: 427 GEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPF 486

Query: 412 G---------------------CGICNKRFKLKHHLTEHMKTH-AGALHACPHCGRRFRV 449
           G                     C  C+K +K    L +H KTH     + C  CG++F  
Sbjct: 487 GGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQ 546

Query: 450 HACFLRH 456
                RH
Sbjct: 547 RGTMTRH 553



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 41/144 (28%), Positives = 60/144 (41%), Gaps = 31/144 (21%)

Query: 330 SGPGPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHGPVKLGGTP-----PADGKR- 383
           +G GP  GGGG                 G PGG G+ +  P +          PA  ++ 
Sbjct: 480 AGLGPPFGGGGDKV-------------AGAPGGLGELLR-PYRCASCDKSYKDPATLRQH 525

Query: 384 ---------FGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTH 433
                    + C +CGK+F  +    RH+     L+PF C  C  RF  ++ LTEHM+ H
Sbjct: 526 EKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIH 585

Query: 434 AGAL-HACPHCGRRFRVHACFLRH 456
           +G   + C  CG +F      + H
Sbjct: 586 SGEKPYECQVCGGKFAQQRNLISH 609



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 382 KRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHA 434
           K F C  CG RF  + +   H+ +    +P+ C +C  +F  + +L  HMK HA
Sbjct: 561 KPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHA 614


>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
          Length = 714

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 138/547 (25%), Positives = 187/547 (34%), Gaps = 132/547 (24%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYF-----HDKLLL 79
           +E P HS  LL  LN  R +G  CDV ++VQ    RAHK VLAA+S Y      HD LL 
Sbjct: 5   MEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLN 64

Query: 80  GDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDA-------------LPAHLLVASGLQ 126
            D        ++    F  +L  IY+GRL    +A             L A L  AS LQ
Sbjct: 65  LD------HDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQ 118

Query: 127 MWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSP-----FQTPV- 180
           +  +V  C    + L+  G     RGG       +     G     ++P     + +PV 
Sbjct: 119 IPDLVALCK---KRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVG 175

Query: 181 -QSSASTESPASTESPVGGEGSEL-----GEVLQIQVEEEEEEEEDDDDEDQGSATLSQT 234
                + E P+  E+ V    +EL     G    +   E         D  + S   S  
Sbjct: 176 PPPPPAAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAA 235

Query: 235 PQ-PQRVSGVFPRPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPK 293
           P+ P     + PRP      P +A P    E    PL LP+ P LP +       P +P 
Sbjct: 236 PERPLAERELPPRPDS----PPSAGPAAYKE---PPLALPSLPPLPFQKLEEAAPPSDPF 288

Query: 294 EEISGS-GTQPGG-----------AKEETKVFSGGD------------TEGNGELGFLLP 329
              SGS G +P G            K E  + S GD             E  G    + P
Sbjct: 289 RGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAVSP 348

Query: 330 SGP---------------GPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHGPVKLG 374
            GP               GP +GG G  +K               PGG  +    P    
Sbjct: 349 GGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGS-SEDPSPPGGHLEGYPCPHLAY 407

Query: 375 GTPPADGKR-FGCL-CGKRFAVKPKRDRHIMLTFSLR---------------------PF 411
           G P + G   + C+ CGK F    + + H+                            PF
Sbjct: 408 GEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAAGLGPPF 467

Query: 412 G---------------------CGICNKRFKLKHHLTEHMKTH-AGALHACPHCGRRFRV 449
           G                     C  C+K +K    L +H KTH     + C  CG++F  
Sbjct: 468 GGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQ 527

Query: 450 HACFLRH 456
                RH
Sbjct: 528 RGTMTRH 534



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 41/144 (28%), Positives = 60/144 (41%), Gaps = 31/144 (21%)

Query: 330 SGPGPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHGPVKLGGTP-----PADGKR- 383
           +G GP  GGGG                 G PGG G+ +  P +          PA  ++ 
Sbjct: 461 AGLGPPFGGGGDKV-------------AGAPGGLGELLR-PYRCASCDKSYKDPATLRQH 506

Query: 384 ---------FGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTH 433
                    + C +CGK+F  +    RH+     L+PF C  C  RF  ++ LTEHM+ H
Sbjct: 507 EKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIH 566

Query: 434 AGAL-HACPHCGRRFRVHACFLRH 456
           +G   + C  CG +F      + H
Sbjct: 567 SGEKPYECQVCGGKFAQQRNLISH 590



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 382 KRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHA 434
           K F C  CG RF  + +   H+ +    +P+ C +C  +F  + +L  HMK HA
Sbjct: 542 KPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHA 595


>gi|139394599 hypermethylated in cancer 2 [Homo sapiens]
          Length = 615

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 137/547 (25%), Positives = 190/547 (34%), Gaps = 133/547 (24%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYF-----HDKLLL 79
           +E P HS  LL  LN+ R +G  CDV ++V+    RAHK VLAA+S YF     HD L+ 
Sbjct: 23  MELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHDNLIN 82

Query: 80  GDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAH------LLVASGLQMWQVVDQ 133
            D        ++ +  F+ +L  IY+G+L LP D  PA       L  AS LQ+ ++   
Sbjct: 83  LDT------DMVSSTVFQQILDFIYTGKL-LPSDQ-PAEPNFSTLLTAASYLQLPELAAL 134

Query: 134 CSEILRELETSGG----GISARGGNSYHALLSTTS------------STGGWCIRSSP-- 175
           C   L+      G    G +  G       LST S              G    +  P  
Sbjct: 135 CRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVDGRKGAHAPQELPQA 194

Query: 176 ------------FQTPVQSSASTESPASTESPVGG-----EGSELGEVLQIQVEEEEEEE 218
                        Q  VQ       PA  E+ +GG      GS  G       E+E   +
Sbjct: 195 KGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG------CEQELGLD 248

Query: 219 EDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHP---LPMTATPRKLPEGESAPLE---- 271
                     AT      P   + +    HG  P    P  A      E    P E    
Sbjct: 249 LSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGGTPDEPMDL 308

Query: 272 ----------LPAPPALPPKIF--YIKQEPFEPKEEISGSGTQ-----PGGAKEETKVFS 314
                     L AP   P K      +++ +  KE ++GS  +     P G     +   
Sbjct: 309 EGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGPCPGEEGEG 368

Query: 315 GGDTEGNGELGFLLPSGPGPTSGGGGPSW--KPVDLHG---NEILSGGGGPGGAGQA-VH 368
            GD   NG    +L SG GP+   G P +  K  + +G   +E  +  G  GG+G A  H
Sbjct: 369 VGDRVPNG----ILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGHASAH 424

Query: 369 GPVKLGG--TPPADGKRFGCL-CGKRFAVKPKRDRHI----------------------- 402
              +  G  T       + C+ C K F    + + H+                       
Sbjct: 425 YMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETGSGGA 484

Query: 403 ------------MLTFSLRPFGCGICNKRFKLKHHLTEHMKTH-AGALHACPHCGRRFRV 449
                         T   RPF C +C K +K    L +H KTH       C  CG+ F  
Sbjct: 485 EEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQ 544

Query: 450 HACFLRH 456
                RH
Sbjct: 545 RGTMTRH 551



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 384 FGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGAL-HACP 441
           F C +CGK F  +    RH+     L+PF C  C  RF  ++ LTEHM+ H+G   + C 
Sbjct: 533 FPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQ 592

Query: 442 HCGRRFRVHACFLRH 456
            CG +F      + H
Sbjct: 593 LCGGKFTQQRNLISH 607



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 2/107 (1%)

Query: 359 GPGGAGQAVHGPVKLGGTPPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICN 417
           G GGA +             A+ + F C +C K +       +H    +  RPF C IC 
Sbjct: 480 GSGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICG 539

Query: 418 KRFKLKHHLTEHMKTHAGAL-HACPHCGRRFRVHACFLRHRDLCKGQ 463
           K F  +  +T HM++H G    AC  CG RF        H  +  G+
Sbjct: 540 KMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGE 586



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 15/53 (28%), Positives = 27/53 (50%), Gaps = 1/53 (1%)

Query: 382 KRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTH 433
           K F C  CG RF  + +   H+ +    +P+ C +C  +F  + +L  H++ H
Sbjct: 559 KPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMH 611


>gi|224591419 zinc finger and BTB domain containing 8B [Homo
           sapiens]
          Length = 495

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 119/477 (24%), Positives = 180/477 (37%), Gaps = 97/477 (20%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLL--LGDA 82
           +E   + + LL  LN  R    FCD S++V+GR  +AH+ +L A S YF   L+  + D+
Sbjct: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60

Query: 83  PRLTLPS--VIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCS----- 135
            R +  S  ++ +DAF  +L  +YSG+L L  + +   +  AS LQM  VV+ C      
Sbjct: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120

Query: 136 --EILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSASTESPASTE 193
             +I R++E      +A    +  A  +  ++                    +ESP+S  
Sbjct: 121 SLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAA---------------HQVDSESPSS-- 163

Query: 194 SPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPL 253
              G EG+  G    +    E E+  +          L ++P      G     H     
Sbjct: 164 ---GREGTSCGTKSLVSSPAEGEKSVE---------CLRESP-----CGDCGDCH----- 201

Query: 254 PMTATPRKLPEGESAPLELPAPP-ALPPKI-FYIKQEPFEPKEEISGSGTQPGGAKEETK 311
           P+    R    G SA   L  PP  + PK+ F   +   +  E++         A  E  
Sbjct: 202 PLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEVDVGEQLQQYAAPLNLAHVEEA 261

Query: 312 VFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHG-- 369
           + SG   +       +             PS    D H +  L   G P GAG A+    
Sbjct: 262 LPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLE--GRPEGAGVAMSSMM 319

Query: 370 -----------------PVKLGGTP--PADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRP 410
                            P+KL   P  P   K+ G L            RHI      RP
Sbjct: 320 DVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGIL-----------KRHIRSHTGERP 368

Query: 411 FGCGICNKRFKLKHHLTEHMKTHAGALH------ACPHCGRRFRVH-ACFLRHRDLC 460
           + C  C KRF  +    EH+++HA ++H       C  C R F  H +  LR   LC
Sbjct: 369 YPCETCGKRFTRQ----EHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGLC 421


>gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]
          Length = 522

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 47/124 (37%), Positives = 69/124 (55%), Gaps = 5/124 (4%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFH----DKLLLG 80
           +EFP HS  LL+ L+  R +G  CD ++LV   + RAH+AVLA+ S YFH    D+L   
Sbjct: 1   MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR 60

Query: 81  DAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRE 140
           D   L    ++ A AF  LL+ +Y G+L+     +   L  AS L M+ +V  C + L+E
Sbjct: 61  DIVHLN-SDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKE 119

Query: 141 LETS 144
             T+
Sbjct: 120 KATT 123



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 29/82 (35%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 377 PPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAG 435
           P AD     C LCGK F+      RH       +P+ C  C K F+  H+L+ H   H  
Sbjct: 403 PAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTR 462

Query: 436 AL-HACPHCGRRFRVHACFLRH 456
              HAC  C RRF       RH
Sbjct: 463 EKPHACKWCERRFTQSGDLYRH 484



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 13/44 (29%), Positives = 19/44 (43%)

Query: 388 CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMK 431
           CGK F       RH ++    +P  C  C +RF     L  H++
Sbjct: 443 CGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIR 486


>gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]
          Length = 531

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 47/124 (37%), Positives = 69/124 (55%), Gaps = 5/124 (4%)

Query: 25  IEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFH----DKLLLG 80
           +EFP HS  LL+ L+  R +G  CD ++LV   + RAH+AVLA+ S YFH    D+L   
Sbjct: 10  MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR 69

Query: 81  DAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRE 140
           D   L    ++ A AF  LL+ +Y G+L+     +   L  AS L M+ +V  C + L+E
Sbjct: 70  DIVHLN-SDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKE 128

Query: 141 LETS 144
             T+
Sbjct: 129 KATT 132



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 29/82 (35%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 377 PPADGKRFGC-LCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAG 435
           P AD     C LCGK F+      RH       +P+ C  C K F+  H+L+ H   H  
Sbjct: 412 PAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTR 471

Query: 436 AL-HACPHCGRRFRVHACFLRH 456
              HAC  C RRF       RH
Sbjct: 472 EKPHACKWCERRFTQSGDLYRH 493



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 13/44 (29%), Positives = 19/44 (43%)

Query: 388 CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMK 431
           CGK F       RH ++    +P  C  C +RF     L  H++
Sbjct: 452 CGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIR 495


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.136    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,986,380
Number of Sequences: 37866
Number of extensions: 1655586
Number of successful extensions: 29977
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1321
Number of HSP's successfully gapped in prelim test: 685
Number of HSP's that attempted gapping in prelim test: 11596
Number of HSP's gapped (non-prelim): 12551
length of query: 473
length of database: 18,247,518
effective HSP length: 106
effective length of query: 367
effective length of database: 14,233,722
effective search space: 5223775974
effective search space used: 5223775974
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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