BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens] (322 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens] 688 0.0 gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens] 642 0.0 gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo... 254 7e-68 gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo... 254 7e-68 gi|5032115 sprouty 2 [Homo sapiens] 241 8e-64 gi|27501452 sprouty homolog 3 [Homo sapiens] 229 3e-60 gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform... 59 8e-09 gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform... 59 8e-09 gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo sa... 57 3e-08 gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a... 55 1e-07 gi|93102379 low density lipoprotein-related protein 1B precursor... 38 0.014 gi|154759249 keratin associated protein 10-11 [Homo sapiens] 37 0.018 gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens] 37 0.031 gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ... 36 0.053 gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 34 0.15 gi|239753765 PREDICTED: hypothetical protein [Homo sapiens] 34 0.15 gi|113415439 PREDICTED: hypothetical protein [Homo sapiens] 34 0.15 gi|113414819 PREDICTED: hypothetical protein [Homo sapiens] 34 0.15 gi|33946327 nucleoporin 214kDa [Homo sapiens] 34 0.20 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 34 0.20 gi|55770876 notch4 preproprotein [Homo sapiens] 34 0.20 gi|60279697 keratin associated protein 5-7 [Homo sapiens] 33 0.26 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 33 0.34 gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 33 0.34 gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 33 0.44 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 33 0.44 gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 33 0.44 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 33 0.44 gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 33 0.44 gi|16554449 zonadhesin isoform 3 [Homo sapiens] 33 0.44 >gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens] Length = 322 Score = 688 bits (1776), Expect = 0.0 Identities = 322/322 (100%), Positives = 322/322 (100%) Query: 1 MLSPLPTGPLEACFSVQSRTSSPMEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTI 60 MLSPLPTGPLEACFSVQSRTSSPMEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTI Sbjct: 1 MLSPLPTGPLEACFSVQSRTSSPMEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTI 60 Query: 61 LPIDQVKTSHVENDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPS 120 LPIDQVKTSHVENDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPS Sbjct: 61 LPIDQVKTSHVENDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPS 120 Query: 121 SVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFL 180 SVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFL Sbjct: 121 SVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFL 180 Query: 181 LCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEG 240 LCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEG Sbjct: 181 LCEACGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEG 240 Query: 241 SCADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKH 300 SCADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKH Sbjct: 241 SCADHPCSCSRSNCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKH 300 Query: 301 TNSVICKAASGDAKTSRPDKPF 322 TNSVICKAASGDAKTSRPDKPF Sbjct: 301 TNSVICKAASGDAKTSRPDKPF 322 >gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens] Length = 299 Score = 642 bits (1657), Expect = 0.0 Identities = 299/299 (100%), Positives = 299/299 (100%) Query: 24 MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL 83 MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL Sbjct: 1 MEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPIDQVKTSHVENDYIDNPSLAL 60 Query: 84 TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV 143 TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV Sbjct: 61 TTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPV 120 Query: 144 ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW 203 ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW Sbjct: 121 ADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCW 180 Query: 204 VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA 263 VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA Sbjct: 181 VCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGA 240 Query: 264 LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF 322 LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF Sbjct: 241 LSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAASGDAKTSRPDKPF 299 >gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo sapiens] Length = 319 Score = 254 bits (649), Expect = 7e-68 Identities = 135/298 (45%), Positives = 186/298 (62%), Gaps = 29/298 (9%) Query: 39 VMVQPLLDSR--MSHSRLQHPLTILPIDQVKTSHVENDYIDNPSL----ALTTGPKRTRG 92 V+ QP LDSR + + R P IL +DQ+K N+Y + PS+ A T P++ + Sbjct: 15 VIQQPSLDSRQRLDYEREIQPTAILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKH 74 Query: 93 GAP-ELAPTPARCDQDVTH-----HWI-------------SFSGRPSSVSSSSSTSSDQR 133 E+ P + + H H + + +G +S S+SS SS+Q Sbjct: 75 ERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQG 134 Query: 134 LLDHMAPP-PVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKE 192 LL P PV S RA+R QPK + DLKG ++ +L +H +CE CGKCKC E Sbjct: 135 LLGRSPPTRPVPGHRSERAIRTQPKQLIVD--DLKG-SLKEDLTQHKFICEQCGKCKCGE 191 Query: 193 CASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRS 252 C +PRTLPSC CN++CLCSA+++V YGTCMCLV+GIFYHC+N+D+ S +D+PCSCS+S Sbjct: 192 CTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSCSQS 251 Query: 253 NCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAAS 310 +CC+R+ MGA+S+ LPCLLCY PA GC+KL +R YD + RPGCRCK++N+V CK S Sbjct: 252 HCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDWIHRPGCRCKNSNTVYCKLES 309 >gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo sapiens] Length = 319 Score = 254 bits (649), Expect = 7e-68 Identities = 135/298 (45%), Positives = 186/298 (62%), Gaps = 29/298 (9%) Query: 39 VMVQPLLDSR--MSHSRLQHPLTILPIDQVKTSHVENDYIDNPSL----ALTTGPKRTRG 92 V+ QP LDSR + + R P IL +DQ+K N+Y + PS+ A T P++ + Sbjct: 15 VIQQPSLDSRQRLDYEREIQPTAILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKH 74 Query: 93 GAP-ELAPTPARCDQDVTH-----HWI-------------SFSGRPSSVSSSSSTSSDQR 133 E+ P + + H H + + +G +S S+SS SS+Q Sbjct: 75 ERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQG 134 Query: 134 LLDHMAPP-PVADQASPRAVRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKE 192 LL P PV S RA+R QPK + DLKG ++ +L +H +CE CGKCKC E Sbjct: 135 LLGRSPPTRPVPGHRSERAIRTQPKQLIVD--DLKG-SLKEDLTQHKFICEQCGKCKCGE 191 Query: 193 CASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRS 252 C +PRTLPSC CN++CLCSA+++V YGTCMCLV+GIFYHC+N+D+ S +D+PCSCS+S Sbjct: 192 CTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSCSQS 251 Query: 253 NCCARWSFMGALSVVLPCLLCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICKAAS 310 +CC+R+ MGA+S+ LPCLLCY PA GC+KL +R YD + RPGCRCK++N+V CK S Sbjct: 252 HCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDWIHRPGCRCKNSNTVYCKLES 309 >gi|5032115 sprouty 2 [Homo sapiens] Length = 315 Score = 241 bits (614), Expect = 8e-64 Identities = 125/276 (45%), Positives = 169/276 (61%), Gaps = 29/276 (10%) Query: 54 LQHPLTILPIDQVKTSHVENDYIDNPSLALTTGPK-----------RTRGGAPELAPTP- 101 L + +L +DQ++ N+Y + P++ G K G PE P Sbjct: 34 LTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPR 93 Query: 102 ---------ARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLL-DHMAPPPVADQASPRA 151 AR + +S R S+ +S+SS+SS+QRLL + PVAD Sbjct: 94 LQHSQVHSSARAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPVADGI---- 149 Query: 152 VRIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQECLC 211 +R+QPK +P +LK P +L H CE CGKCKCKEC PR LPS W+C+++CLC Sbjct: 150 IRVQPKS-ELKPGELK-PLSKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLC 207 Query: 212 SAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGALSVVLPCL 271 SAQ +++YGTC+C V+G+FYHC+N DDE +CAD+PCSCS+S+CC RWS MG +S+ LPCL Sbjct: 208 SAQNVIDYGTCVCCVKGLFYHCSN-DDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCL 266 Query: 272 LCYLPATGCVKLAQRGYDRLRRPGCRCKHTNSVICK 307 CYLPA GC+KL Q YDR+ RPGCRCK++N+V CK Sbjct: 267 WCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCK 302 >gi|27501452 sprouty homolog 3 [Homo sapiens] Length = 288 Score = 229 bits (583), Expect = 3e-60 Identities = 124/285 (43%), Positives = 163/285 (57%), Gaps = 49/285 (17%) Query: 60 ILPIDQVKTSHVENDYIDNP----------------------SLA-LTTGPKRTRGGAPE 96 ILPI+Q++++H NDY++ P SLA + T R+ + Sbjct: 12 ILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQ 71 Query: 97 LAPTPARCDQDVTHHWISFSGRPSSVSSS---SSTSSDQRLLDHMAPPPVADQASPRAVR 153 L P P Q SS++SS S+T+SDQRLL + P P + +R Sbjct: 72 LQPLPQHLSQ-------------SSIASSMSHSTTASDQRLLASITPSP----SGQSIIR 114 Query: 154 IQPKVVHCQPLD--LKGPAVPP--ELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQEC 209 QP D LKG A +H +CE CG+CKC C + R LPSCW+CNQ C Sbjct: 115 TQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRC 174 Query: 210 LCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGALSVVLP 269 LCSA++L++YGTC+C V+G+FYHC+ DDE +CAD PCSC S+C RW+ M +S+ LP Sbjct: 175 LCSAESLLDYGTCLCCVKGLFYHCST-DDEDNCADEPCSCGPSSCFVRWAAMSLISLFLP 233 Query: 270 CLLCYLPATGCVKLAQRGYDRLRRPGCRCK-HTNSVICKAASGDA 313 CL CYLP GC+ L Q+GYD LRRPGCRCK HTN+V K +SG A Sbjct: 234 CLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSA 278 >gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform b [Homo sapiens] Length = 415 Score = 58.5 bits (140), Expect = 8e-09 Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 4/76 (5%) Query: 207 QECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGAL 264 Q+ S +T + +CM + YHC + D EG D PCSC S+ C RW + AL Sbjct: 324 QDAPDSVRTCIRRVSCMWCADSMLYHCMS-DPEGDYTD-PCSCDTSDEKFCLRWMALIAL 381 Query: 265 SVVLPCLLCYLPATGC 280 S + PC+ CYLP C Sbjct: 382 SFLAPCMCCYLPLRAC 397 >gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform a [Homo sapiens] Length = 418 Score = 58.5 bits (140), Expect = 8e-09 Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 4/76 (5%) Query: 207 QECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGAL 264 Q+ S +T + +CM + YHC + D EG D PCSC S+ C RW + AL Sbjct: 327 QDAPDSVRTCIRRVSCMWCADSMLYHCMS-DPEGDYTD-PCSCDTSDEKFCLRWMALIAL 384 Query: 265 SVVLPCLLCYLPATGC 280 S + PC+ CYLP C Sbjct: 385 SFLAPCMCCYLPLRAC 400 >gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo sapiens] Length = 444 Score = 56.6 bits (135), Expect = 3e-08 Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 4/62 (6%) Query: 221 TCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSN--CCARWSFMGALSVVLPCLLCYLPAT 278 +CM + + YHC + D EG +D PCSC S+ C RW + ALS ++PC+ CY+P Sbjct: 367 SCMLCAESMLYHCMS-DSEGDFSD-PCSCDTSDDKFCLRWLALVALSFIVPCMCCYVPLR 424 Query: 279 GC 280 C Sbjct: 425 MC 426 >gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a [Homo sapiens] Length = 410 Score = 54.7 bits (130), Expect = 1e-07 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Query: 216 LVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNC--CARWSFMGALSVVLPCLLC 273 LV +C+ + + YHC + D EG +D PC+C + ARW+ + ALS+ +PCL C Sbjct: 325 LVRRLSCLWCAESLLYHCLS-DAEGDFSD-PCACEPGHPRPAARWAALAALSLAVPCLCC 382 Query: 274 YLPATGCVKLAQR 286 Y P C +A R Sbjct: 383 YAPLRACHWVAAR 395 >gi|93102379 low density lipoprotein-related protein 1B precursor [Homo sapiens] Length = 4599 Score = 37.7 bits (86), Expect = 0.014 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 23/85 (27%) Query: 193 CASPRTLPSCWVCNQECLCSAQT----LVNYGTCMCLVQGIF---------YHCTNEDDE 239 C + R +P W+C++E C QT + TC L Q + +HC ++DD Sbjct: 934 CGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDC 993 Query: 240 G----------SCADHPCSCSRSNC 254 G SC D+ CS C Sbjct: 994 GDGSDEVGCVHSCFDNQFRCSSGRC 1018 Score = 28.9 bits (63), Expect = 6.4 Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 17/78 (21%) Query: 192 ECASPRTLPSCWVCN--QEC---------LCSAQTL----VNYGTCMCLVQGIFYHCTNE 236 +C + R +P W+C+ +C C+A+T + G C+ + + C E Sbjct: 892 KCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRA--WLCDRE 949 Query: 237 DDEGSCADHPCSCSRSNC 254 DD G D SC C Sbjct: 950 DDCGDQTDEMASCEFPTC 967 >gi|154759249 keratin associated protein 10-11 [Homo sapiens] Length = 298 Score = 37.4 bits (85), Expect = 0.018 Identities = 54/237 (22%), Positives = 80/237 (33%), Gaps = 53/237 (22%) Query: 97 LAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVADQASPR----AV 152 L TP C V+ + PS+ S ++S + P +SP V Sbjct: 45 LVCTPVSC---VSSPCCQAACEPSACQSGCTSSCTPSCCQQSSCQPACCTSSPCQQACCV 101 Query: 153 RIQPKVVHCQPLDLKGPAVPPELDKHFLLCEACGKCKCKE-------CASPRTLPSCWV- 204 + K V C+P+ VP + C A C C++ CAS P+C V Sbjct: 102 PVCCKTVCCKPVC----CVP-------VCCGAASSC-CRQSSCQPACCASSSCQPACCVP 149 Query: 205 --CNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMG 262 C C S TC +ED C C + CC S+ Sbjct: 150 VCCKPVCCVS--------TC------------SEDSSSCCQQSSCQPA---CCTSSSYQQ 186 Query: 263 ALSVVLPCLLCYLPATGCVKLAQR-GYDRLRRPGCRCKHTNSVICKAASGDAKTSRP 318 A V + C Y CV + R R ++P C+ + C+ +S + P Sbjct: 187 ACCVPVCCKTVYCKPICCVPVCSRASSSRCQQPSCQPACCTTSCCRPSSSVSLLCHP 243 >gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens] Length = 474 Score = 36.6 bits (83), Expect = 0.031 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 61 LPIDQVKTSHVENDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWIS-FSGRP 119 LP+++ HV + NP ++ G KR + E +P + VT +S FS Sbjct: 26 LPVEE----HVGSQTFVNPHVSSFQGSKRGLNSSFETSPKKVKWSSTVTSPRLSLFSDGD 81 Query: 120 SSVSSSSSTSSDQRLLDHMAPP-----PVADQASPRAVRIQPKVVHCQP 163 SS S + +SS++ PP P + SP+ R P+ C P Sbjct: 82 SSESEDTLSSSERSKGSGSRPPTPKSSPQKTRKSPQVTRGSPQKTSCSP 130 >gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) [Homo sapiens] Length = 494 Score = 35.8 bits (81), Expect = 0.053 Identities = 29/100 (29%), Positives = 38/100 (38%), Gaps = 26/100 (26%) Query: 185 CGKCKCKE------CASPRTL-----PSCWVC--NQECLCSAQTLVNYGTCMC------- 224 CGKCKC + C P S +C +Q+ +CS + G C C Sbjct: 112 CGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSG 171 Query: 225 LVQGIF-----YHCTNEDDEGSCADH-PCSCSRSNCCARW 258 LV G F C +++ E C H C C C A W Sbjct: 172 LVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGW 211 >gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens] Length = 4544 Score = 34.3 bits (77), Expect = 0.15 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 18/80 (22%) Query: 193 CASPRTLPSCWVCNQECLCSAQT----LVNYGTCMCLVQ---------GIFYHCTNEDDE 239 CAS R +P W C+ + C ++ Y TC L Q I + C N++D Sbjct: 943 CASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDC 1002 Query: 240 GSCAD-----HPCSCSRSNC 254 G +D H CS ++ C Sbjct: 1003 GDNSDEAGCSHSCSSTQFKC 1022 Score = 29.6 bits (65), Expect = 3.8 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 17/78 (21%) Query: 192 ECASPRTLPSCWVCN-----------QECLCSAQTL-VNYGTC---MCLVQGIFYHCTNE 236 +C + R +P+ W+C+ CSA+T N +C C+ I + C + Sbjct: 901 KCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCI--PISWTCDLD 958 Query: 237 DDEGSCADHPCSCSRSNC 254 DD G +D SC+ C Sbjct: 959 DDCGDRSDESASCAYPTC 976 Score = 29.3 bits (64), Expect = 4.9 Identities = 22/90 (24%), Positives = 30/90 (33%), Gaps = 32/90 (35%) Query: 183 EACGKCKCK----ECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDD 238 E C + C+ C + R +P W C+ + C + D Sbjct: 3529 EECDERTCEPYQFRCKNNRCVPGRWQCDYD----------------------NDCGDNSD 3566 Query: 239 EGSCADHPC-----SCSRSNCCA-RWSFMG 262 E SC PC SC+ C A RW G Sbjct: 3567 EESCTPRPCSESEFSCANGRCIAGRWKCDG 3596 >gi|239753765 PREDICTED: hypothetical protein [Homo sapiens] Length = 192 Score = 34.3 bits (77), Expect = 0.15 Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 11/126 (8%) Query: 15 SVQSRTSSPMEPPIPQSAPLTPNSV-MVQPLLDSRMSHSRLQHPLTILPIDQVKT-SHVE 72 S+ S P++P LT SV M+Q + H L LT + ++T SH Sbjct: 64 SMIQTVSHPIQPHPHLDQFLTTQSVSMIQTVSHPIQPHPHLDQFLTTQSVSMIQTVSHPT 123 Query: 73 NDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISF------SGRPSSVSSSS 126 ++D T + + + P P D +T+H ISF S P+S SSSS Sbjct: 124 QPHLDQ--FLTTQSVSMIQTVSHPIQPHP-HLDPFLTNHPISFNDPDCQSPHPASASSSS 180 Query: 127 STSSDQ 132 SDQ Sbjct: 181 GPVSDQ 186 >gi|113415439 PREDICTED: hypothetical protein [Homo sapiens] Length = 206 Score = 34.3 bits (77), Expect = 0.15 Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 11/126 (8%) Query: 15 SVQSRTSSPMEPPIPQSAPLTPNSV-MVQPLLDSRMSHSRLQHPLTILPIDQVKT-SHVE 72 S+ S P++P LT SV M+Q + H L LT + ++T SH Sbjct: 78 SMIQTVSHPIQPHPHLDQFLTTQSVSMIQTVSHPIQPHPHLDQFLTTQSVSMIQTVSHPT 137 Query: 73 NDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISF------SGRPSSVSSSS 126 ++D T + + + P P D +T+H ISF S P+S SSSS Sbjct: 138 QPHLDQ--FLTTQSVSMIQTVSHPIQPHP-HLDPFLTNHPISFNDPDCQSPHPASASSSS 194 Query: 127 STSSDQ 132 SDQ Sbjct: 195 GPVSDQ 200 >gi|113414819 PREDICTED: hypothetical protein [Homo sapiens] Length = 206 Score = 34.3 bits (77), Expect = 0.15 Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 11/126 (8%) Query: 15 SVQSRTSSPMEPPIPQSAPLTPNSV-MVQPLLDSRMSHSRLQHPLTILPIDQVKT-SHVE 72 S+ S P++P LT SV M+Q + H L LT + ++T SH Sbjct: 78 SMIQTVSHPIQPHPHLDQFLTTQSVSMIQTVSHPIQPHPHLDQFLTTQSVSMIQTVSHPT 137 Query: 73 NDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISF------SGRPSSVSSSS 126 ++D T + + + P P D +T+H ISF S P+S SSSS Sbjct: 138 QPHLDQ--FLTTQSVSMIQTVSHPIQPHP-HLDPFLTNHPISFNDPDCQSPHPASASSSS 194 Query: 127 STSSDQ 132 SDQ Sbjct: 195 GPVSDQ 200 >gi|33946327 nucleoporin 214kDa [Homo sapiens] Length = 2090 Score = 33.9 bits (76), Expect = 0.20 Identities = 45/177 (25%), Positives = 69/177 (38%), Gaps = 22/177 (12%) Query: 8 GPLEACFSVQSRTS---SPMEPPI-PQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPI 63 GP F S+ S +P P+ P +A + S +P L+S S + + P Sbjct: 516 GPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPS 575 Query: 64 DQVKTSHVENDYIDNPSLALTTGPKRTRGGAPELAPTPARCDQDVT---HHWISFSGRPS 120 TS V+ + + + A T+ P + AP ++P + + H S PS Sbjct: 576 FPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPS 635 Query: 121 SVSSSSS------------TSSDQRLLDHMAP---PPVADQASPRAVRIQPKVVHCQ 162 SV SS +SS + +P PP A SP+A +QP V Q Sbjct: 636 SVPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQ 692 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 33.9 bits (76), Expect = 0.20 Identities = 48/193 (24%), Positives = 69/193 (35%), Gaps = 25/193 (12%) Query: 5 LPTGPL-EACFSVQSRTSSPMEPPIPQSAPLT--PNSVMVQPLLDSRMS-------HSRL 54 LP PL EA + SP+ PP P+ +PL+ P S PL +S +S L Sbjct: 474 LPASPLPEALHLSRPLEESPLSPP-PEESPLSPPPESSPFSPLEESPLSPPEESPPSPAL 532 Query: 55 QHPLTILPIDQVKTSHVENDYIDNPSLALTTGP---KRTRGGAPELAP-------TPARC 104 + PL+ P + E + P L T P PE +P +P Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592 Query: 105 DQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVADQASP----RAVRIQPKVVH 160 + + + F P S S S ++PPP SP + P+V Sbjct: 593 PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652 Query: 161 CQPLDLKGPAVPP 173 PL + PP Sbjct: 653 LSPLPVVSRLSPP 665 >gi|55770876 notch4 preproprotein [Homo sapiens] Length = 2003 Score = 33.9 bits (76), Expect = 0.20 Identities = 26/87 (29%), Positives = 30/87 (34%), Gaps = 15/87 (17%) Query: 182 CEACGKCKCKECASPRTLPSC---WV---CNQECLCSAQTLVNYGTCMCLVQGIFYHC-- 233 C G+C + AS R SC W C CSA VN G C+ I HC Sbjct: 127 CSKRGRCHIQ--ASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPP 184 Query: 234 -----TNEDDEGSCADHPCSCSRSNCC 255 E D C P C + C Sbjct: 185 GFEGHACERDVNECFQDPGPCPKGTSC 211 >gi|60279697 keratin associated protein 5-7 [Homo sapiens] Length = 165 Score = 33.5 bits (75), Expect = 0.26 Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 7/74 (9%) Query: 185 CGKCKCKECASPRTLPSCWVCNQECLCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCAD 244 CG C C +C+ + P C C+ C S C C C + SC Sbjct: 87 CGSCGCSQCSCYK--PCC--CSSGCGSSCCQSSCCKPCCCQSSCCKPCCCSSGCGSSCCQ 142 Query: 245 HPC---SCSRSNCC 255 C CS+S+CC Sbjct: 143 SSCCNPCCSQSSCC 156 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 33.1 bits (74), Expect = 0.34 Identities = 44/182 (24%), Positives = 72/182 (39%), Gaps = 23/182 (12%) Query: 2 LSPLPTGPLEACFSVQSRTSSPMEPP---IPQSAPLTPNSVMVQPLLDSRMSHSRLQHPL 58 +SPL P +A ++ + + P P AP +P++ + L + + P+ Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP---PV 834 Query: 59 TILPIDQVKTSHVENDYIDNPSLALTTGPKRTRGG-------APELAPTPARCDQDVTHH 111 P+ QV S + + P T GP + G AP P P+R Sbjct: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS---- 890 Query: 112 WISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRIQPKVVHCQPLD-LKGPA 170 + SG + SSS+TS+ + L + + P ASP ++ C P +GPA Sbjct: 891 --TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP---DAELAACHPAAWSRGPA 945 Query: 171 VP 172 P Sbjct: 946 PP 947 Score = 28.9 bits (63), Expect = 6.4 Identities = 51/198 (25%), Positives = 72/198 (36%), Gaps = 38/198 (19%) Query: 3 SPLPTGPLEACFSVQSRT-----SSPMEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHP 57 SPL PL+A S+ S + SS + PP+ + L P S+ P + ++ L++ Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP---ASLTTPPLENL 538 Query: 58 LTILP------IDQVKTSHVEND------YIDNPSLALTTGPKRTRGG---APELAPTPA 102 ++ P + T H+E + P LTT P T P AP PA Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP-PA 597 Query: 103 RCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRIQPKVVHCQ 162 + G PS S +T Q +A PP+ SP P Sbjct: 598 LASPPL-------QGLPSPPLSPLATPPPQ-APPXLALPPLQAPPSP------PASPPLS 643 Query: 163 PLDLKGPAVPPELDKHFL 180 PL P P L H L Sbjct: 644 PLATPSPQAPNALAVHLL 661 Score = 28.5 bits (62), Expect = 8.4 Identities = 40/165 (24%), Positives = 62/165 (37%), Gaps = 36/165 (21%) Query: 23 PMEPPIPQSAPLTPNSVMVQPLLDS--------------RMSHSRLQHPLTILPIDQVKT 68 P PP+ PL P S P L + M+ +Q P ++ I ++ Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV 391 Query: 69 SH-VENDYIDNP--SLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSS 125 H + + + P LAL++ T G+P L TH +++ S R + S + Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTL---------QATHSFLTMSPRQTQASLT 442 Query: 126 S-----STSSD----QRLLDHMAPPPVADQASPRAVRI-QPKVVH 160 S ST D Q L A PP+ SP + P +H Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487 >gi|150170722 G protein-coupled receptor 50 [Homo sapiens] Length = 617 Score = 33.1 bits (74), Expect = 0.34 Identities = 35/141 (24%), Positives = 49/141 (34%), Gaps = 10/141 (7%) Query: 29 PQSAPLTPNSVMVQPLLDSRMS---HSR------LQHPLTILPIDQVKTSHVENDYIDNP 79 P S P S +P+ +S HS+ HP + TSH E D P Sbjct: 462 PDSVHFKPASSNPKPITGHHVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYP 521 Query: 80 SLALTTGPKRTRGGAPELAPTPARCDQDVTHHWISFSGRPSSVSSSSSTSSDQRLLDHMA 139 A T+ PK T PEL+ + + H S P S +SS + + + Sbjct: 522 KPATTSHPKPTAADNPELSASHCPEIPAIAHPVSDDSDLPES-ASSPAAGPTKPAASQLE 580 Query: 140 PPPVADQASPRAVRIQPKVVH 160 +AD P V H Sbjct: 581 SDTIADLPDPTVVTTSTNDYH 601 >gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein [Homo sapiens] Length = 1403 Score = 32.7 bits (73), Expect = 0.44 Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 8/78 (10%) Query: 178 HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 231 H+ LC C ++P S C + C+C A T V G C CL G +Y Sbjct: 744 HYELCGDSCPVSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYY 801 Query: 232 HCTNEDDEGSCADHPCSC 249 G + C C Sbjct: 802 PLGEVFYPGPECERRCEC 819 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 32.7 bits (73), Expect = 0.44 Identities = 48/176 (27%), Positives = 69/176 (39%), Gaps = 28/176 (15%) Query: 5 LPTGPLEACFSVQSRTSSPMEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPID 64 L T PL+A S + S P + P SA L P S + P + P+ P+ Sbjct: 523 LATPPLQALPSPPA--SFPGQAPFSPSASL-PMSPLATPPPQAP--------PVLAAPLL 571 Query: 65 QVKTSHVENDYIDNPSLALTTGPKRTRGG-------APELAPTPARCDQDVTHHWISFSG 117 QV S + + P T GP + G AP P P+R + SG Sbjct: 572 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS------TLSG 625 Query: 118 RPSSVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRIQPKVVHCQPLD-LKGPAVP 172 + SSS+TS+ + L + + P ASP ++ C P +GPA P Sbjct: 626 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP---DAELAACHPAAWSRGPAPP 678 >gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo sapiens] Length = 3003 Score = 32.7 bits (73), Expect = 0.44 Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 8/78 (10%) Query: 178 HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 231 H+ LC C ++P S C + C+C A T V G C CL G +Y Sbjct: 2344 HYELCGDSCPVSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYY 2401 Query: 232 HCTNEDDEGSCADHPCSC 249 G + C C Sbjct: 2402 PLGEVFYPGPECERRCEC 2419 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 32.7 bits (73), Expect = 0.44 Identities = 48/176 (27%), Positives = 69/176 (39%), Gaps = 28/176 (15%) Query: 5 LPTGPLEACFSVQSRTSSPMEPPIPQSAPLTPNSVMVQPLLDSRMSHSRLQHPLTILPID 64 L T PL+A S + S P + P SA L P S + P + P+ P+ Sbjct: 484 LATPPLQALPSPPA--SFPGQAPFSPSASL-PMSPLATPPPQAP--------PVLAAPLL 532 Query: 65 QVKTSHVENDYIDNPSLALTTGPKRTRGG-------APELAPTPARCDQDVTHHWISFSG 117 QV S + + P T GP + G AP P P+R + SG Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS------TLSG 586 Query: 118 RPSSVSSSSSTSSDQRLLDHMAPPPVADQASPRAVRIQPKVVHCQPLD-LKGPAVP 172 + SSS+TS+ + L + + P ASP ++ C P +GPA P Sbjct: 587 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP---DAELAACHPAAWSRGPAPP 639 >gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] Length = 5405 Score = 32.7 bits (73), Expect = 0.44 Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 8/78 (10%) Query: 178 HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 231 H+ LC C ++P S C + C+C A T V G C CL G +Y Sbjct: 4744 HYELCGDSCPVSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYY 4801 Query: 232 HCTNEDDEGSCADHPCSC 249 G + C C Sbjct: 4802 PLGEVFYPGPECERRCEC 4819 Score = 30.4 bits (67), Expect = 2.2 Identities = 21/78 (26%), Positives = 27/78 (34%), Gaps = 8/78 (10%) Query: 178 HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 231 H+ LC C ++P S C + C+C A T V G C CL +Y Sbjct: 2342 HYELCGDSCPGSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYY 2399 Query: 232 HCTNEDDEGSCADHPCSC 249 G D C C Sbjct: 2400 PLGQTFYPGPGCDSLCRC 2417 Score = 30.4 bits (67), Expect = 2.2 Identities = 21/78 (26%), Positives = 27/78 (34%), Gaps = 8/78 (10%) Query: 178 HFLLCEACGKCKCKECASPRTLPSCWVCNQECLCSA------QTLVNYGTCMCLVQGIFY 231 H+ LC C ++P S C + C+C A T V G C CL +Y Sbjct: 3543 HYELCGDSCPGSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYY 3600 Query: 232 HCTNEDDEGSCADHPCSC 249 G D C C Sbjct: 3601 PLGQTFYPGPGCDSLCRC 3618 >gi|16554449 zonadhesin isoform 3 [Homo sapiens] Length = 2812 Score = 32.7 bits (73), Expect = 0.44 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 14/78 (17%) Query: 188 CKCK-ECASPRTLPSCW-VCNQECLCSAQTL------VNYGTCMCLVQGIFYHCTNEDDE 239 C C C SPR PSC +C + C+C+ L + +C C +Y E Sbjct: 1053 CACPASCKSPR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFS 1110 Query: 240 GSCADHPCSC---SRSNC 254 +C +H C C SR C Sbjct: 1111 PNCTEH-CRCWPGSRVEC 1127 Score = 30.0 bits (66), Expect = 2.9 Identities = 21/72 (29%), Positives = 26/72 (36%), Gaps = 9/72 (12%) Query: 190 CKECASPRTLPSCWVCNQECLC------SAQTLVNYGTCMCLVQGIFYHCTNED--DEGS 241 C +PR P C + C C S + V G C C YH E E + Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888 Query: 242 CADHPCSCSRSN 253 C C+CS N Sbjct: 1889 CT-RLCTCSVHN 1899 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.133 0.441 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,894,827 Number of Sequences: 37866 Number of extensions: 866569 Number of successful extensions: 3934 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 111 Number of HSP's that attempted gapping in prelim test: 3677 Number of HSP's gapped (non-prelim): 332 length of query: 322 length of database: 18,247,518 effective HSP length: 102 effective length of query: 220 effective length of database: 14,385,186 effective search space: 3164740920 effective search space used: 3164740920 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.