Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 229608967
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|229608967 spermatogenic leucine zipper 1 [Homo sapiens]
(430 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|229608967 spermatogenic leucine zipper 1 [Homo sapiens] 848 0.0
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 144 1e-34
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 64 3e-10
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 62 1e-09
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 60 3e-09
gi|71061468 centromere protein E [Homo sapiens] 60 3e-09
gi|55770834 centromere protein F [Homo sapiens] 57 4e-08
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 56 6e-08
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 56 7e-08
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 56 7e-08
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 55 9e-08
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 55 1e-07
gi|151101140 coiled-coil domain containing 2 isoform a [Homo sap... 55 1e-07
gi|151105223 coiled-coil domain containing 2 isoform a [Homo sap... 55 1e-07
gi|151105229 coiled-coil domain containing 2 isoform a [Homo sap... 55 1e-07
gi|32698688 citron [Homo sapiens] 54 3e-07
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 54 4e-07
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 53 5e-07
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 53 5e-07
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 53 5e-07
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 53 5e-07
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 53 6e-07
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 53 6e-07
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 53 6e-07
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 52 8e-07
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 52 8e-07
gi|16262452 cingulin [Homo sapiens] 52 8e-07
gi|219803769 trichoplein [Homo sapiens] 52 1e-06
gi|14150056 trichoplein [Homo sapiens] 52 1e-06
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 52 1e-06
>gi|229608967 spermatogenic leucine zipper 1 [Homo sapiens]
Length = 430
Score = 848 bits (2191), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MASSAKSAEMPTISKTVNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQV 60
MASSAKSAEMPTISKTVNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQV
Sbjct: 1 MASSAKSAEMPTISKTVNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQV 60
Query: 61 TEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKIN 120
TEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKIN
Sbjct: 61 TEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKIN 120
Query: 121 EMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLA 180
EMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLA
Sbjct: 121 EMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLA 180
Query: 181 PEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEET 240
PEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEET
Sbjct: 181 PEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEET 240
Query: 241 MKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAK 300
MKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAK
Sbjct: 241 MKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAK 300
Query: 301 HELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQ 360
HELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQ
Sbjct: 301 HELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQ 360
Query: 361 DKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKACNTQFNIHVARKALR 420
DKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKACNTQFNIHVARKALR
Sbjct: 361 DKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKACNTQFNIHVARKALR 420
Query: 421 GKMRSASSLR 430
GKMRSASSLR
Sbjct: 421 GKMRSASSLR 430
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 144 bits (364), Expect = 1e-34
Identities = 127/473 (26%), Positives = 225/473 (47%), Gaps = 66/473 (13%)
Query: 12 TISKTVNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQVTEQQTAQKFNN 71
T+ V P PD + P A I S + W ++ +K+ +QVTEQQ ++K
Sbjct: 1163 TLPDDVQPGPDFYGLPWKPVFITAFLGIASFAIFLWRTVLVVKDRVYQVTEQQISEKLKT 1222
Query: 72 LLKEIKDILKNMAGFEEKITEAKELFEETN-----ITEDVSAHKENIRGLDKINEML--- 123
++KE ++++ ++ +E+KI E+K+ +ET ++++ +K+ I+ L+K E+L
Sbjct: 1223 IMKENTELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTLEKNQEILDDT 1282
Query: 124 STNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTN------LPV 177
+ NL V L E+E N K Q++I EN + ++K+ +++S N + +
Sbjct: 1283 AKNLRVMLESEREQNVKNQDLI------------SENKKSIEKLKDVISMNASEFSEVQI 1330
Query: 178 SLAPEKEDNEKKQ----QMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNR 233
+L K EK + ++ EN + + +++ + + L+E +S EK++
Sbjct: 1331 ALNEAKLSEEKVKSECHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQIKSFEKSQKD 1390
Query: 234 LNV-----QEETMKIRNNMEQLL-----QEAEHWSKQHTELSKL------------IKSY 271
L V + + N + QL E+E +K + +L +K+
Sbjct: 1391 LEVALTHKDDNINALTNCITQLNLLECESESEGQNKGGNDSDELANGEVGGDRNEKMKNQ 1450
Query: 272 QKSQKDISETLGNNGVG------FQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLE 325
K D+S T V Q + VS K LE+QVKKL D SLQ A LE
Sbjct: 1451 IKQMMDVSRTQTAISVVEEDLKLLQLKLRASVSTKCNLEDQVKKLEDDRNSLQAAKAGLE 1510
Query: 326 NECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQK--------PSEAKKVEMYK 377
+EC+ L+Q+VEIL EL+ QK+ LQ+K Q Y++ ++ + S A++V+ YK
Sbjct: 1511 DECKTLRQKVEILNELYQQKEMALQKKLSQEEYERQEREHRLSAADEKAVSAAEEVKTYK 1570
Query: 378 QNKQAMKGTFWKKDRSCRSLDVCLNKKACNTQFNIHVARKALRGKMRSASSLR 430
+ + M+ K +RS ++ KKA A +A+ + R A++LR
Sbjct: 1571 RRIEEMEDELQKTERSFKNQIATHEKKAHENWLKARAAERAIAEEKREAANLR 1623
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 63.9 bits (154), Expect = 3e-10
Identities = 82/334 (24%), Positives = 147/334 (44%), Gaps = 52/334 (15%)
Query: 100 TNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKE 159
T + E+++ K NI L + N L + + L ++ E + + ++ ++ +K
Sbjct: 270 TKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLE-----VTKVDVETELQTYKH 324
Query: 160 NIRGLDKI-NEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARD--------- 209
+ +GLD++ NE S + +NE Q+ M+++ E ++ +D
Sbjct: 325 SRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHE-IELAMKLLEKDIHEKQDTLI 383
Query: 210 -LVNRLEEKKVLN-----ETQQSQE--KAKNRL--NVQEETMKIRNNMEQLLQEAEHWSK 259
L +LEE K +N + Q S++ K KN + ++E+T KI M QL Q + K
Sbjct: 384 GLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQRLQQAEK 443
Query: 260 QHTE--------LSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKK-- 309
E L + + QK IS+ V +T E + L+E ++K
Sbjct: 444 AQMEAEDEDEKYLQECLSKSDSLQKQISQK-EKQLVQLETDLKIEKEWRQTLQEDLQKEK 502
Query: 310 --LSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKP 367
LSH Q + +L + E LQ + LK+++H+++ LQE K
Sbjct: 503 DALSHLRNETQQIISL-KKEFLNLQDENQQLKKIYHEQEQALQEL-----------GNKL 550
Query: 368 SEAK-KVEMYKQNKQAMKGTFWKKDRSCRSLDVC 400
SE+K K+E K+ +A++G W KD+ +C
Sbjct: 551 SESKLKIEDIKEANKALQGLVWLKDKEATHCKLC 584
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 61.6 bits (148), Expect = 1e-09
Identities = 87/394 (22%), Positives = 168/394 (42%), Gaps = 62/394 (15%)
Query: 61 TEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGL---- 116
T++QT + +K++ ++L++ G K TE E E T + H ++ L
Sbjct: 297 TQKQTLNARDESIKKLLEMLQSK-GLSAKATE--EDHERTRRLAEAEMHVHHLESLLEQK 353
Query: 117 DKINEMLSTNLPVSL--APEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTN 174
+K N ML + AP+ + Q +I + +S+ + +R L++ +ML +N
Sbjct: 354 EKENSMLREEMHRRFENAPDSAKTKALQTVIEMKD--SKISSMERGLRDLEEEIQMLKSN 411
Query: 175 LPVSLAPEKEDNEKKQQMI-------MENQNSENTAQVFARD------------LVNRLE 215
+L+ E+ + E KQ + M+N+ + ++ +D L N+
Sbjct: 412 --GALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFS 469
Query: 216 EKK----VLNETQQSQEKAKN---------RLNVQEETMKIRNNMEQLLQEAEHWSKQHT 262
+ K VL E+ ++E+ RL ++E+ + +Q+ AE Q
Sbjct: 470 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAG 529
Query: 263 ELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAA 322
E+ L ++ ++ L Q Q ++ L+E+VK L DT +
Sbjct: 530 EIHDLKDMLDVKERKVN-VLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 588
Query: 323 LLENECQILQQRVEILKELHHQKQGTLQEKPIQI-NYKQDKKNQK-----------PSEA 370
LE ++ +E LKE Q+ +EK +I NYK+D K+ K EA
Sbjct: 589 TLEEALAEKERTIERLKE---QRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEA 645
Query: 371 KKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKK 404
+++ K++ ++ + KKD ++L++ L +K
Sbjct: 646 SLLDL-KEHASSLASSGLKKDSRLKTLEIALEQK 678
Score = 42.4 bits (98), Expect = 8e-04
Identities = 50/297 (16%), Positives = 130/297 (43%), Gaps = 21/297 (7%)
Query: 62 EQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINE 121
E++ ++ +N K++KD+ + ++ + ++E +E ++ D+ H ++ +
Sbjct: 612 EREKQEEIDNYKKDLKDLKEKVSLLQGDLSE-----KEASLL-DLKEHASSLASSGLKKD 665
Query: 122 MLSTNLPVSLAPEKEDN-------EKKQEMILETNITEDVSAHKENIRGLDKINEMLSTN 174
L ++L +KE+ +K E LE + ++S + I+ L++ E+
Sbjct: 666 SRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS---DRIQHLER--EITRYK 720
Query: 175 LPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRL 234
S A + D + +EN+ ++ ++ + + + KKV N + Q + K
Sbjct: 721 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA 780
Query: 235 NVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPN 294
+ EE + +N+ Q+ + ++ + I+ +++ ++ + + + +
Sbjct: 781 QMLEEARRREDNLNDSSQQLQDSLRKKDD---RIEELEEALRESVQITAEREMVLAQEES 837
Query: 295 NEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQE 351
+A+ ++EE + + L+ M A L + Q L ++ L L +++ L+E
Sbjct: 838 ARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEE 894
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 60.5 bits (145), Expect = 3e-09
Identities = 63/329 (19%), Positives = 142/329 (43%), Gaps = 22/329 (6%)
Query: 65 TAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETN--ITEDVSAHKENIRGLDKINEM 122
T K NL +E+ + +N++ K+T+ K+ +E + +D+ ++ + GL KIN
Sbjct: 975 TENKVKNLSEEMTALEENIS----KLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAK 1030
Query: 123 LSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPE 182
L E++ ++ + + E + D+ K + G K+++ +L
Sbjct: 1031 L----------EQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI 1080
Query: 183 KEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKN--RLNVQEET 240
+E +KK+ + + Q + QV + +++E + E + + +A++ R ++++
Sbjct: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140
Query: 241 MKIRNNMEQL---LQEAEHWSKQHTELSKLIKS-YQKSQKDISETLGNNGVGFQTQPNNE 296
+ +E++ L+EA + E++K ++ +QK ++D+ E + T +
Sbjct: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200
Query: 297 VSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQI 356
+ EL EQ+ L L+ + L+ E + +E L + + T + Q
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260
Query: 357 NYKQDKKNQKPSEAKKVEMYKQNKQAMKG 385
+ + K Q+ + M K Q G
Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNG 1289
Score = 52.0 bits (123), Expect = 1e-06
Identities = 83/372 (22%), Positives = 166/372 (44%), Gaps = 55/372 (14%)
Query: 53 LKNSSHQVTEQ-QTAQKFN-NLLKEIKDILKNMAGFEEKITEA---KELFEETNITEDVS 107
++N+ +V +Q +T ++ N NL +EI D+ + +A + + EA K+L E+ D+
Sbjct: 1488 MRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEK--SDLQ 1545
Query: 108 AHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENI-RGLDK 166
E + G + E + + L+ K + ++K ++E + E++ K N R +
Sbjct: 1546 VALEEVEGSLEHEESKILRVQLELSQVKSELDRK---VIEKD--EEIEQLKRNSQRAAEA 1600
Query: 167 INEMLSTN-------LPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKV 219
+ +L L + E + NE + Q+ N+ T Q R + +L++ ++
Sbjct: 1601 LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET-QKHLRTVQGQLKDSQL 1659
Query: 220 -LNETQQSQEKAKNRLNVQE----------ETMKI---------RNNMEQLLQEAEHWSK 259
L++ +S E K +L + E E MK+ R + ++LL ++
Sbjct: 1660 HLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQL 1719
Query: 260 QHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHE------LEEQVKKLSHD 313
H++ + LI + +K + DI++ Q N E AK + E++KK
Sbjct: 1720 LHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDT 1779
Query: 314 TYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKV 373
+ L+ M LE + LQ R++ ++L K G Q + ++ N ++ +N+ E K+
Sbjct: 1780 SAHLERMKKNLEQTVKDLQHRLDEAEQL-ALKGGKKQIQKLE-NRVRELENELDVEQKR- 1836
Query: 374 EMYKQNKQAMKG 385
+A+KG
Sbjct: 1837 -----GAEALKG 1843
Score = 46.2 bits (108), Expect = 6e-05
Identities = 49/209 (23%), Positives = 94/209 (44%), Gaps = 18/209 (8%)
Query: 160 NIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNR--LEEK 217
NIR + NL + P + E +++M ++ E T + AR R LEEK
Sbjct: 821 NIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEK 880
Query: 218 KVL-----NETQ-QSQEKAKNRLNVQEET---MKIRNNMEQLLQEAEHWSKQHTELSKLI 268
V N+ Q Q Q + +N ++ +E +K + +E ++E ++ E++ +
Sbjct: 881 MVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSEL 940
Query: 269 KSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENEC 328
+ +++ +D +L + + KH E +VK LS + M AL EN
Sbjct: 941 VAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEE------MTALEENIS 994
Query: 329 QILQQRVEILKELHHQKQGTLQEKPIQIN 357
++ +++ + L+E H Q LQ + ++N
Sbjct: 995 KLTKEK-KSLQEAHQQTLDDLQVEEDKVN 1022
Score = 38.5 bits (88), Expect = 0.012
Identities = 57/262 (21%), Positives = 103/262 (39%), Gaps = 30/262 (11%)
Query: 66 AQKFNNLLKEIKDILKNMAGFE-EKITEAKELFEETNITEDVSAHKENIRGLDKINEMLS 124
A + N LKE I++ G E++ E K E+T T +S +E + D++ + S
Sbjct: 1664 ALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLS-EQELLDASDRVQLLHS 1722
Query: 125 TNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKE 184
N + N KK+ LE +I + A EN + E + A E
Sbjct: 1723 QNTSLI-------NTKKK---LEADIAQ-CQAEVENSIQESRNAEEKAKKAITDAAMMAE 1771
Query: 185 DNEKKQQMIMENQNSENTAQVFARDLVNRLEE---------KKVLNETQQSQEKAKNRLN 235
+ +K+Q + + + +DL +RL+E KK + + + + +N L+
Sbjct: 1772 ELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELD 1831
Query: 236 VQEE--------TMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGV 287
V+++ K ++++ +AE K L L+ Q K
Sbjct: 1832 VEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEE 1891
Query: 288 GFQTQPNNEVSAKHELEEQVKK 309
TQ + +HELEE ++
Sbjct: 1892 QANTQLSRCRRVQHELEEAAER 1913
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 60.5 bits (145), Expect = 3e-09
Identities = 73/355 (20%), Positives = 160/355 (45%), Gaps = 34/355 (9%)
Query: 53 LKNSSHQVTEQQ--TAQKFNNLLKEIKDILKNMAGFEEKITE--AKELFEETNITEDVSA 108
LK+ H T ++ N L+ +K + + + KI+E ++ L E N E
Sbjct: 948 LKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDE 1007
Query: 109 HKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQE-----MILETN----ITEDVSAHKE 159
++ + G+DK ++ + N A K++ +Q+ +I E N + E V A KE
Sbjct: 1008 FQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKE 1067
Query: 160 NIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEE--K 217
++ K N ++ L ++ +K+Q+++ + +N + +RL E +
Sbjct: 1068 QLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEE 1127
Query: 218 KVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKD 277
K+ ++QQ QEK + LNVQEE + M++ + E E+ + ++ + + +
Sbjct: 1128 KLKEKSQQLQEKQQQLLNVQEE----MSEMQKKINEIENLKNELKNKELTLEHMETERLE 1183
Query: 278 ISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEI 337
+++ L N + ++ + ++ ++++K S +T L + E E LQ + E+
Sbjct: 1184 LAQKLNEN-----YEEVKSITKERKVLKELQK-SFETERDHLRGYIREIEATGLQTKEEL 1237
Query: 338 -LKELH---HQK-----QGTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAM 383
+ +H HQ+ + ++ EK QI QD + +++ + + ++ +
Sbjct: 1238 KIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELL 1292
Score = 57.8 bits (138), Expect = 2e-08
Identities = 92/355 (25%), Positives = 151/355 (42%), Gaps = 49/355 (13%)
Query: 55 NSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAH----- 109
N +TEQ T + L + + L+ F+E E K L +E + + +
Sbjct: 1306 NELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKH 1365
Query: 110 ---KENIR-GLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLD 165
KE+IR L KI E S SL +++DNE T I ++ K L
Sbjct: 1366 DQLKEHIRETLAKIQESQSKQ-EQSLNMKEKDNE-------TTKIVSEMEQFKPKDSALL 1417
Query: 166 KIN-EMLSTNLPV--------SLAPEKEDNEKKQQMIM--ENQNSENTAQVFARDLVNRL 214
+I EML + + S+A EK+D ++ Q+++ +Q EN ++ A+ L
Sbjct: 1418 RIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETE- 1476
Query: 215 EEKKVLNETQQSQEKAKN--RLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQ 272
EE KV + + QE+ N R+N+ E+ +I +QL EA + Q+ K Q
Sbjct: 1477 EELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQL--EAINDKLQNKIQEIYEKEEQ 1534
Query: 273 KSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQ 332
+ K ISE +V+ + +E K S++ L N Q Q
Sbjct: 1535 FNIKQISEV------------QEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQ 1582
Query: 333 QRVEI-LKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGT 386
+ ++I +KE K+ ++ +QI Q K+N K AK E ++ Q +K T
Sbjct: 1583 EEIQIMIKEKEEMKR---VQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMT 1634
Score = 57.0 bits (136), Expect = 3e-08
Identities = 96/407 (23%), Positives = 176/407 (43%), Gaps = 80/407 (19%)
Query: 58 HQVTEQ-QTAQKFNNLLKEIKDILKN-------MAGFEEKITEAKELFEETNIT------ 103
H TE+ + AQK N +E+K I K FE + + E T
Sbjct: 1176 HMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1235
Query: 104 EDVSAH---KENIRGLDKINEMLS--TNLPVSLAPEKEDNEKKQEMI--------LETNI 150
E AH KE+ +D++ +S T ++ ++ + K QE I L N+
Sbjct: 1236 ELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNV 1295
Query: 151 TEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDL 210
E VS +E + L+ + E +T +LA + + + + E+Q E + RD
Sbjct: 1296 KE-VSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQE-EIKSLTKERDN 1353
Query: 211 VNRLEE-------------KKVLNETQQSQEKAKNRLNVQE---ETMKIRNNMEQ----- 249
+ ++E ++ L + Q+SQ K + LN++E ET KI + MEQ
Sbjct: 1354 LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKD 1413
Query: 250 ---------LLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPN-NEVSA 299
+L ++ + H E+ + K Q+ + E L + Q + N E+ A
Sbjct: 1414 SALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQR-LQEVLQSE--SDQLKENIKEIVA 1470
Query: 300 KH-ELEEQVK------KLSHDTYS-LQLMAALLENECQILQQRVEILKELHHQKQGTLQE 351
KH E EE++K K +T + L++ + E E +Q+++E + + K + E
Sbjct: 1471 KHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYE 1530
Query: 352 KPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLD 398
K Q N KQ + Q+ + +++ +K++++A KD + +S++
Sbjct: 1531 KEEQFNIKQISEVQE--KVNELKQFKEHRKA-------KDSALQSIE 1568
Score = 45.1 bits (105), Expect = 1e-04
Identities = 74/372 (19%), Positives = 152/372 (40%), Gaps = 41/372 (11%)
Query: 54 KNSSHQVTEQQTAQKFNNLLKEIKDILKN----MAGFEEKITEAKELFEETNITEDVSA- 108
K + + Q+ N LK+ K+ K + E K+ E +E+ +
Sbjct: 1531 KEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIK 1590
Query: 109 HKENIRGLDKI----NEMLSTNLPVSLAPEKEDNEKKQEMILET-------------NIT 151
KE ++ + + + L N +A KE EK+ + + T ++
Sbjct: 1591 EKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLK 1650
Query: 152 EDVSAHKENIRGLD----KINEMLSTNLPV--SLAPEKEDNEKKQQMIM--ENQNSENTA 203
E K N+ ++ ++ ++L NL S+ E++D ++ + +Q EN
Sbjct: 1651 EQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLR 1710
Query: 204 QVFARDLVNRLEEKKVLNETQQSQEKA-KNRLNVQEETMKIRNNMEQLLQEAEHWSKQHT 262
+ RDL + E K V ++ QE K R V E+T +I N + L + Q
Sbjct: 1711 ETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDL 1770
Query: 263 ELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVS--------AKHELEEQVKKLSHDT 314
++ + ++ K+ ET+ + G ++ +++S + +L+E++++L +
Sbjct: 1771 KIQEELRIAHMHLKEQQETI-DKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANE 1829
Query: 315 YSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVE 374
+ L + + NE Q +E LK+ + TL + I+ K ++ E K V
Sbjct: 1830 HQLITLKKDV-NETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVM 1888
Query: 375 MYKQNKQAMKGT 386
+ N + ++ T
Sbjct: 1889 KERDNLRRVEET 1900
Score = 44.7 bits (104), Expect = 2e-04
Identities = 81/352 (23%), Positives = 152/352 (43%), Gaps = 51/352 (14%)
Query: 68 KFNNLLKEI-KDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEM-LST 125
K +L KE+ K++ +N A EE I L E ++ +V ++ I+ DK E+ + T
Sbjct: 721 KITDLQKELNKEVEENEALREEVIL----LSELKSLPSEVERLRKEIQ--DKSEELHIIT 774
Query: 126 NLPVSLAPEKEDNEKKQEMILET--NITEDVSAHKENIRGLDKINEMLST---NLPVSLA 180
+ L E E + + +LE +D++ + N + D+ + T +
Sbjct: 775 SEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYK 834
Query: 181 PEKEDNEKKQQMIMENQNSENTAQVFARDL----------VNRLEEK-----KVLNETQQ 225
E+NE+ Q I+ N AQ F L L+EK + LNE +Q
Sbjct: 835 MVLEENERMNQEIV---NLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQ 891
Query: 226 SQEKAKNR----LNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQ----KSQKD 277
+E+ +NR V+ E I ++Q L+E + +++ +L +L +S Q + + D
Sbjct: 892 LKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSD 951
Query: 278 ISETLGNNGVGFQTQPNNEVSAKHELEEQV----KKLSHD-TYSLQLMAALLENECQILQ 332
I +T+ N + Q Q N + + + +E + K+S + + +L + E + + Q
Sbjct: 952 IHDTV-NMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQ 1010
Query: 333 QRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMK 384
+ V I K+ L+ K Q K N+ + +K+ Q K ++
Sbjct: 1011 KMVGI------DKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ 1056
Score = 42.7 bits (99), Expect = 6e-04
Identities = 77/350 (22%), Positives = 157/350 (44%), Gaps = 49/350 (14%)
Query: 58 HQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVS-AH---KENI 113
H Q+T K ++ E + + NM E +A + ++ I E++ AH KE
Sbjct: 1729 HLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKA-QDLKIQEELRIAHMHLKEQQ 1787
Query: 114 RGLDKINEMLSTNLPVSLAPEKE---DNEKKQEMILETNITEDVSAHKENIRGLDK-INE 169
+DK+ ++S +K+ N K QE I +++ A++ + L K +NE
Sbjct: 1788 ETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKI------QELKANEHQLITLKKDVNE 1841
Query: 170 MLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEK 229
T VS + + K Q + + EN A+ L LEE K S K
Sbjct: 1842 ---TQKKVSEMEQLKKQIKDQSLTLSKLEIENLN--LAQKLHENLEEMK-------SVMK 1889
Query: 230 AKNRLNVQEETMKI-RNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLG--NNG 286
++ L EET+K+ R+ +++ LQE + + E+ + +K+ + K+ ET+
Sbjct: 1890 ERDNLRRVEETLKLERDQLKESLQETK---ARDLEIQQELKTARMLSKEHKETVDKLREK 1946
Query: 287 VGFQTQPNNEV-----SAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKEL 341
+ +T +++ +K EL++++++L LQL+ ++ + + +++ +++L
Sbjct: 1947 ISEKTIQISDIQKDLDKSKDELQKKIQELQKK--ELQLLR--VKEDVNMSHKKINEMEQL 2002
Query: 342 HHQ--KQGTLQEKPIQINYKQDKKNQKPSE-----AKKVEMYKQNKQAMK 384
Q Q + N++ KK + E AK+ + ++ K+++K
Sbjct: 2003 KKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLK 2052
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 56.6 bits (135), Expect = 4e-08
Identities = 75/350 (21%), Positives = 157/350 (44%), Gaps = 33/350 (9%)
Query: 53 LKNSSHQVTEQ-QTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKE 111
LK S+H + + + Q + L K + ++ ++ E +EL +E ++++A
Sbjct: 930 LKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKR--EIEELTQENGTLKEINASLN 987
Query: 112 NIRGLDKINEMLSTNLPVSLAPEKE-------DNEKKQEMIL-----ET-NITEDVSAHK 158
+K+N + + + E+E D K++++IL ET N ED+S
Sbjct: 988 Q----EKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKY 1043
Query: 159 ENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARD----LVNRL 214
+ + + E L K + E+ ++ + T FA + L+ L
Sbjct: 1044 KAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLEL 1103
Query: 215 E--EKKVLNETQQSQEKAKNRLN-VQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSY 271
E ++ + +E +Q +K+ +++E M ++ ++ +E +++ +L K++K+
Sbjct: 1104 ETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTK 1163
Query: 272 QKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQL--MAALLENECQ 329
+ Q SE + N V + N+ + K +++ +VK++S D+Y+ QL + A+L N+
Sbjct: 1164 HECQNLESEPI-RNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKEL 1222
Query: 330 ILQQRVEILKELHHQKQ---GTLQEKPIQINYKQDKKNQKPSEAKKVEMY 376
LQ+ + + L H+ Q G L+ +Q Q+ K E E Y
Sbjct: 1223 KLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKY 1272
Score = 44.3 bits (103), Expect = 2e-04
Identities = 66/289 (22%), Positives = 133/289 (46%), Gaps = 35/289 (12%)
Query: 72 LLKEIKDILKNMAGFE-EKITEAKEL----FEETNITEDVSAHKENIRGLDKINEMLSTN 126
L+KE + + ++ + EK+ +K L E+ +S+ +E + L + E L
Sbjct: 2068 LVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVR 2127
Query: 127 LPVSLAPEKEDNEKKQEMILET--NITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKE 184
+ E +EKKQ I E + + K+ + L++ +M N + + +
Sbjct: 2128 I--------EADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAEN 2179
Query: 185 DNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIR 244
+ + + + + + +VF DLV EK+ N T+Q QEK + +L+ E K+
Sbjct: 2180 SKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE--NLTKQIQEK-QGQLS---ELDKLL 2233
Query: 245 NNMEQLLQEAEHWSKQHTELSK-LIKSYQKSQKDISETL----GNNGVGFQTQPNNE--V 297
++ + LL+E E Q E SK ++ Q K+++E + G+ + T+ + + +
Sbjct: 2234 SSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPI 2293
Query: 298 SAKHELEEQVKKL-----SHDTYSLQLMAALLENE--CQILQQRVEILK 339
+H+L ++KL + + L ++ L E+E +L+ RVE L+
Sbjct: 2294 EEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLE 2342
Score = 43.9 bits (102), Expect = 3e-04
Identities = 66/336 (19%), Positives = 136/336 (40%), Gaps = 47/336 (13%)
Query: 55 NSSHQVTEQQTAQ-KFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENI 113
N H E + ++ + L +I+ + +++ G E + + E+ N+T ++ +E I
Sbjct: 2351 NQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRS--EKENLTNELQKEQERI 2408
Query: 114 RGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLST 173
L+ IN N+ EK ++K +E T+ + E + L E
Sbjct: 2409 SELEIINSSFE-NILQEKEQEKVQMKEKSSTAMEMLQTQ-LKELNERVAALHNDQEACKA 2466
Query: 174 NLP-VSLAPEKEDNEKKQ--QMIMENQNSENTAQVFARDLVNRLEE-KKVLNETQQSQEK 229
+S E + EK Q Q + E +N+ Q L+ +E+ K+ L + + +
Sbjct: 2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISR 2526
Query: 230 AKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGF 289
KN++ QE+ + + + Q+ E + W +Q+ EL L
Sbjct: 2527 LKNQIQDQEQLV---SKLSQVEGEHQLWKEQNLELRNLTV-------------------- 2563
Query: 290 QTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEIL---KELHHQKQ 346
ELE++++ L SLQ +L++ + L+ +E+ K +K
Sbjct: 2564 ------------ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2611
Query: 347 GTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQA 382
+ K ++ + + QK +E ++ ++N+ A
Sbjct: 2612 NKMTAKETELQREMHEMAQKTAELQEELSGEKNRLA 2647
Score = 43.1 bits (100), Expect = 5e-04
Identities = 74/344 (21%), Positives = 136/344 (39%), Gaps = 56/344 (16%)
Query: 54 KNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENI 113
K H + + ++ N+ LK+ + L+ E+ E L E N +V K I
Sbjct: 2133 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAE-NSKAEVETLKTQI 2191
Query: 114 RGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLST 173
+ + ++ +L V+L EKE N+T+ + + + LDK+ +
Sbjct: 2192 EEMARSLKVFELDL-VTLRSEKE------------NLTKQIQEKQGQLSELDKLLSSFKS 2238
Query: 174 NLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNR 233
L EK+Q I + S+ ++ L E L Q+ + +
Sbjct: 2239 LL----------EEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2288
Query: 234 LNVQ-EETMKIRNNMEQL-----------------LQEAEHWSKQHTELSKLIKSYQKSQ 275
L+ EE ++RN++E+L L+E+EH H +L K + +
Sbjct: 2289 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH----HADLLKGRVENLERE 2344
Query: 276 KDISETLGNNGVGFQTQPNNEVS---AKHE-LEEQVKKLSHDTYSLQLMAALLENECQIL 331
+I+ T + EV AK E + + ++ L D +++ L NE Q
Sbjct: 2345 LEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKE 2404
Query: 332 QQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVEM 375
Q+R+ L+ ++ + LQEK +Q+K K + +EM
Sbjct: 2405 QERISELEIINSSFENILQEK------EQEKVQMKEKSSTAMEM 2442
Score = 41.2 bits (95), Expect = 0.002
Identities = 90/433 (20%), Positives = 175/433 (40%), Gaps = 67/433 (15%)
Query: 38 EIGSHSPSSWGSLPFLKNSSH----QVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEA 93
E+ P++ + FL N Q+ ++T+ + LL I+D + + E + E
Sbjct: 1748 ELSFSGPNALVPMDFLGNQEDIHNLQLRVKETSNENLRLLHVIEDRDRKV---ESLLNEM 1804
Query: 94 KELFEETNITE-------DVSAHKENIRG-LDKINEMLSTNLPVSLAPEKEDNEKKQEMI 145
KEL + ++ E + E I G L K N LS L + E Q +
Sbjct: 1805 KELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSC---DHQELLQRVE 1861
Query: 146 LETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNS------ 199
+ D+ H + D + + N D+ K++ + +EN+ S
Sbjct: 1862 TSEGLNSDLEMHADKSSREDIGDNVAKVN----------DSWKERFLDVENELSRIRSEK 1911
Query: 200 ---ENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEH 256
E+ A DL EK L + ++++K + ++EE + + QL E +
Sbjct: 1912 ASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVI--VCLEEELSVVTSERNQLRGELDT 1969
Query: 257 WSKQHTELSKLIKSYQKSQKDI----SETL-----GNNGVGFQTQPNNEVSA-------- 299
SK+ T L +L + ++ +++ SE L V +T+ +S+
Sbjct: 1970 MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKD 2029
Query: 300 KHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYK 359
K L+E+++ L D+ +L L LEN+ L + E+L + Q L E
Sbjct: 2030 KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSE-------- 2081
Query: 360 QDKKNQKPSEAKKVEMYKQNKQAMK--GTFWKKDRSCRSLDVCLNKKACNTQFNIHVARK 417
D + S+A + + ++ + A++ T + + R ++ + + + +H+A K
Sbjct: 2082 SDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEK 2141
Query: 418 ALRGKMRSASSLR 430
L+ + R SL+
Sbjct: 2142 -LKERERENDSLK 2153
Score = 39.7 bits (91), Expect = 0.005
Identities = 67/325 (20%), Positives = 141/325 (43%), Gaps = 57/325 (17%)
Query: 54 KNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKIT-----------EAKELFEET-N 101
KN+S Q T + + NL E++ + F EK+ E E+ ++T
Sbjct: 2575 KNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAE 2634
Query: 102 ITEDVSAHKENIRG-----LDKI----NEMLSTNLPVSLAPEKEDNEKKQEMILETNITE 152
+ E++S K + G L++I +++ L S + D K ++ E + E
Sbjct: 2635 LQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVRE 2694
Query: 153 DVSAHKENIRGLDKINE--MLSTN--LPVSLAPEKEDNEKKQQMIME------------- 195
+++ ++ + +K ++ +L TN V + +E K++ +
Sbjct: 2695 EIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKE 2754
Query: 196 --NQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQE 253
N + + T Q+ +++ K +N+ ++ E+A+ ++ + ++ K +++LQ+
Sbjct: 2755 ELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQK 2814
Query: 254 AEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSH- 312
ELS+L ++ Q+ QK + T+ + V T E+ K LEE+ K+
Sbjct: 2815 ---------ELSQL-QAAQEKQK--TGTVMDTKVDELTTEIKEL--KETLEEKTKEADEY 2860
Query: 313 -DTY-SLQLMAALLENECQILQQRV 335
D Y SL + LE ++L+ +V
Sbjct: 2861 LDKYCSLLISHEKLEKAKEMLETQV 2885
Score = 38.1 bits (87), Expect = 0.016
Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 26/137 (18%)
Query: 293 PNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVE---------------- 336
P + ELE Q+ KL + Q LE Q +Q+VE
Sbjct: 13 PTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRL 72
Query: 337 --ILKELHHQKQGT---LQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGTFWKKD 391
I + L KQ LQ K Q+N+++ + N S K++E +Q + K +
Sbjct: 73 MEICESLEKTKQKISHELQVKESQVNFQEGQLN---SGKKQIEKLEQELKRCKSELERSQ 129
Query: 392 RSCRSLDVCLNKKACNT 408
++ +S DV LN CNT
Sbjct: 130 QAAQSADVSLN--PCNT 144
Score = 35.4 bits (80), Expect = 0.10
Identities = 90/389 (23%), Positives = 148/389 (38%), Gaps = 101/389 (25%)
Query: 49 SLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFE---EKITEAKELF-----EET 100
S LK H + +Q K + KE K +L + + E++ E K LF E
Sbjct: 570 SQDLLKKREHHI--EQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENE 627
Query: 101 NITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKEN 160
+ + + KEN++ KIN L T L E NE+ + + ++ E++S N
Sbjct: 628 KLLTQMESEKENLQS--KINH-LETCLKTQQIKSHEYNERVRTLEMDR---ENLSVEIRN 681
Query: 161 IRGL--DKINEMLSTNLP-VSLAPEKEDNEKKQQMIMEN---QNSENTAQV--------- 205
+ + K E+ + L + L + E +++K Q +EN + S+ T QV
Sbjct: 682 LHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQL 741
Query: 206 --------------------FARDLVNRLEEKKVLNETQQ------SQEKAKNR--LNVQ 237
RDL+ + V NE Q Q+ A + N+
Sbjct: 742 LSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANII 801
Query: 238 EETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQ---KSQKDISETLGNNGVGFQTQPN 294
E + + + EA+ K L + S + +SQK ++ L Q Q
Sbjct: 802 GEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDL-------QKQCE 854
Query: 295 NEVSAKHELEE------------------QVKKLSHDTYSLQLMAA----LLEN---ECQ 329
V K E+EE ++ KL DT + Q + A LEN E Q
Sbjct: 855 ELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQ 914
Query: 330 ILQQRVEI-------LKELHHQKQGTLQE 351
+L +VE LK+ +H + +L+E
Sbjct: 915 LLNDKVETEQAEIQELKKSNHLLEDSLKE 943
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 56.2 bits (134), Expect = 6e-08
Identities = 88/389 (22%), Positives = 149/389 (38%), Gaps = 72/389 (18%)
Query: 59 QVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETN-ITEDVSAHKENIRGLD 117
Q+ Q A + + + ++KN E KI E E EE I +++A K + D
Sbjct: 891 QLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLE--D 948
Query: 118 KINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPV 177
+ +E+ + L K + EK N+TE+++ E I L K + L
Sbjct: 949 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQ 1008
Query: 178 SLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLE-EKKVLNETQQSQEKAKNRLNV 236
+L + + +K + E DL LE EKK+ + ++++ K + L +
Sbjct: 1009 TLDDLQAEEDKVNILTKAKTKLEQQVD----DLEGSLEQEKKLRMDLERAKRKLEGDLKL 1064
Query: 237 -QEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQ-------------------- 275
QE TM + N+ +QL ++ E K+ E+S LI + Q
Sbjct: 1065 AQESTMDMENDKQQLDEKLE---KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL 1121
Query: 276 -------------------------KDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKL 310
++ISE L G T E++ K E E Q KL
Sbjct: 1122 GEEIEAERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQVELNKKREAEFQ--KL 1177
Query: 311 SHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEA 370
D L A L++E V L++ H L E+ + + K ++ SE
Sbjct: 1178 RRD-----LEEATLQHEAM-----VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSEL 1227
Query: 371 K-KVEMYKQNKQAMKGTFWKKDRSCRSLD 398
K + + N +A+ ++ CRSL+
Sbjct: 1228 KMETDDLSSNAEAISKAKGNLEKMCRSLE 1256
Score = 50.8 bits (120), Expect = 2e-06
Identities = 76/363 (20%), Positives = 152/363 (41%), Gaps = 44/363 (12%)
Query: 63 QQTAQKFNNLLKEIKDILKNMAGFEEKITEA-KELFEETNITEDVSAHKENIRG-LDKIN 120
+++ + L +E K++ + ++ E+I E K++ E I + V K I+ L++
Sbjct: 1492 EESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAE 1551
Query: 121 EMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLA 180
L L + E N+ K E+ + I E + R ++ E + + L +
Sbjct: 1552 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIR 1609
Query: 181 PEKEDNEKKQQMIMENQNSE----NTAQVFARDLVNRLEEKKVLNETQ-------QSQEK 229
+ K++M + E + ++ A L N + +L ETQ + QE
Sbjct: 1610 SRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQED 1669
Query: 230 AKNRLNVQE------------------ETMKIRNNMEQ-LLQEAEHWSKQHTELSKLIKS 270
K +L + E +T + R EQ LL +E HT+ + LI +
Sbjct: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1729
Query: 271 YQKSQKDISETLGNNGVGFQTQPNNEVSAKHE------LEEQVKKLSHDTYSLQLMAALL 324
+K + D+S+ Q N E AK + E++KK + L+ M L
Sbjct: 1730 KKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNL 1789
Query: 325 ENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQ---DKKNQKPSEAKKVEMYKQNKQ 381
E + LQ R++ ++L K G Q + ++ ++ + +N++ A+ V+ +++++
Sbjct: 1790 EQTVKDLQHRLDEAEQL-ALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHER 1848
Query: 382 AMK 384
+K
Sbjct: 1849 RVK 1851
Score = 31.6 bits (70), Expect = 1.5
Identities = 41/200 (20%), Positives = 89/200 (44%), Gaps = 39/200 (19%)
Query: 193 IMENQNSENTAQVFARD------LVNRLEEKKVLNETQQS---QEKAKNRLNVQE-ETMK 242
++E E AQ+ R + R+E +K+L + Q + +NV+ MK
Sbjct: 775 LLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMK 834
Query: 243 IRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHE 302
+ ++ LL+ AE E++ + + +QK++ +++++ + + E
Sbjct: 835 LFFKIKPLLKSAE----TEKEMATMKEEFQKTKDELAKS---------------EAKRKE 875
Query: 303 LEEQVKKLSHDTYSLQLMA-------ALLENEC-QILQQRVEILKELHHQKQGTLQEKPI 354
LEE++ L + LQL A E C Q+++ ++++ ++ + +E+ I
Sbjct: 876 LEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEI 935
Query: 355 --QINYKQDKKNQKPSEAKK 372
++ K+ K + SE KK
Sbjct: 936 NAELTAKKRKLEDECSELKK 955
Score = 30.4 bits (67), Expect = 3.2
Identities = 45/267 (16%), Positives = 109/267 (40%), Gaps = 19/267 (7%)
Query: 73 LKEIKDILKNMAGF-EEKITEAKELFEETNITEDVSAHKENIRGLDKINEMLSTNLPVSL 131
LKE I++ A + +I E E+T + + A +E + +++ + + N +
Sbjct: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSRKI-AEQELLDASERVQLLHTQNTSLIN 1728
Query: 132 APEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQ 191
+K +N+ Q L++ + E + + R ++ + T+ + K++ +
Sbjct: 1729 TKKKLENDVSQ---LQSEVEEVI----QESRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1781
Query: 192 MIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLL 251
+ +N E T +DL +RL+E + L ++ K V+E ++ N ++
Sbjct: 1782 LERMKKNLEQTV----KDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNA 1837
Query: 252 QEAEHWSKQHTELSKLIKSYQKSQK------DISETLGNNGVGFQTQPNNEVSAKHELEE 305
+ + K + +L ++ +K D+ + L ++ Q +
Sbjct: 1838 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLS 1897
Query: 306 QVKKLSHDTYSLQLMAALLENECQILQ 332
+ +KL H+ + A + E++ L+
Sbjct: 1898 KFRKLQHELEEAEERADIAESQVNKLR 1924
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 55.8 bits (133), Expect = 7e-08
Identities = 69/339 (20%), Positives = 148/339 (43%), Gaps = 31/339 (9%)
Query: 53 LKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKEN 112
L+ V + Q L + ++I + + ++ T+ +EL E+ +E +
Sbjct: 358 LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAA----- 412
Query: 113 IRGLDKINEMLSTNLPVSLAPEKEDNEKKQEM--ILETNITEDVSAHKENIRGLDKINEM 170
+++ + LST A K E +++ I +T+ E +S +E R ++ ++
Sbjct: 413 ---FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDV 469
Query: 171 LSTNLPVSLAP-----EKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEK--KVLNET 223
+ + +A EKE K+Q++ + Q E Q + + + + + K+ E
Sbjct: 470 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEK 529
Query: 224 QQSQEKAKNRLNVQEETM--KIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISET 281
+Q + A L +Q++ + + N + L QEAE + + EL ++ + K+ S+
Sbjct: 530 EQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKD 589
Query: 282 LGNNGVGFQTQPNNEVSA---KHELEEQVKKLSHD---TYSLQLMAALLENECQILQQRV 335
L + + + N E++ KH+ E + K D T LQ++ + E + L+++
Sbjct: 590 LAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKC 649
Query: 336 EILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVE 374
E +K+ L++K I ++ N+K E V+
Sbjct: 650 E------QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682
Score = 54.3 bits (129), Expect = 2e-07
Identities = 81/379 (21%), Positives = 149/379 (39%), Gaps = 40/379 (10%)
Query: 63 QQTAQKFNNLLKEIKDILK-NMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINE 121
++ Q+ LLK+ + I + ++ EK E ++ ++T + S E ++ K+ E
Sbjct: 647 EKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDV-KQTELESLSSELSEVLKARHKLEE 705
Query: 122 MLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAP 181
LS +D K + LE + E + H++ + + K +E+ +L
Sbjct: 706 ELSV---------LKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKD 756
Query: 182 EKEDNE----KKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQ 237
+ E ++ + + E+Q + + L++ + QS + A +
Sbjct: 757 QINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATH----- 811
Query: 238 EETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEV 297
E+T + QL Q+ + L+K + + +KD+ L + + Q
Sbjct: 812 EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLE 871
Query: 298 SAKHELEEQVKKLSH---------DTYSLQLMAALLENECQILQQRVEILKELHHQKQG- 347
E+E++VK L+ + Q L+E E ILQ R KE+ Q
Sbjct: 872 KQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKL 931
Query: 348 TLQEKPIQI---NYKQDKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKK 404
+ +E I I Y+ KNQ+ KK+E KQ + M+ T KK + L K+
Sbjct: 932 SAKEDSIHILNEEYETKFKNQE----KKMEKVKQKAKEMQETLKKK---LLDQEAKLKKE 984
Query: 405 ACNTQFNIHVARKALRGKM 423
NT + K KM
Sbjct: 985 LENTALELSQKEKQFNAKM 1003
Score = 50.4 bits (119), Expect = 3e-06
Identities = 59/279 (21%), Positives = 124/279 (44%), Gaps = 26/279 (9%)
Query: 140 KKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNS 199
K+QE +L+ E + +HKE L E L L L ++ EK + + M +
Sbjct: 289 KRQENLLK-RCKETIQSHKEQCTLLTSEKEALQEQLDERL----QELEKIKDLHMAEKTK 343
Query: 200 ENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSK 259
T A++L+ +LE+ K + + ++ + +EE ++R+ ++Q+ + E +
Sbjct: 344 LITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELRE 403
Query: 260 QHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQL 319
Q +KS++ E L Q K E++EQ+K + + S +
Sbjct: 404 QK----------EKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTI--EKTSEEE 451
Query: 320 MAALLENECQILQQRVEILKELHHQKQGTLQE--------KPIQINYKQDKKNQKPSEAK 371
+L + ++ Q+ V+++K+ ++ LQ+ K ++ K + ++ E
Sbjct: 452 RISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQM 511
Query: 372 KVEMYKQNKQAMKGTFWKKDRSCRSL-DVCLNKKACNTQ 409
KV + K + +K + K+ + +L ++ L KKA T+
Sbjct: 512 KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTE 550
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/441 (19%), Positives = 185/441 (41%), Gaps = 77/441 (17%)
Query: 53 LKNSSHQVTEQQTA-----QKFNNLLKEIKDILKNM-AGFEEKITEAKELFEETNITEDV 106
L+ Q+TE+Q Q+ + L+E ++ +K+M A E +TE + L +E +
Sbjct: 1274 LEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQA 1333
Query: 107 SAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDK 166
++ KE+ + ++ + LS N+ ++E EKK E+ + D++ +N L +
Sbjct: 1334 ASEKESC--ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSE 1391
Query: 167 -------------------INEMLSTNLPV-SLAPEK---------------EDNEKKQQ 191
++++ + V +L+ EK E +K Q
Sbjct: 1392 KEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQS 1451
Query: 192 MIMENQNSENTAQVF----ARDLVNRLEEKKVLNETQQSQEKA-----------KNRLNV 236
++QN+ Q+ +++ + E+ +L E Q K K+++
Sbjct: 1452 RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEK 1511
Query: 237 QEETMK--IRNNMEQLLQEAEHWSKQHTE---LSKLIKSYQKSQKDIS-ETLGNNGVGFQ 290
+E ++ +++ ++++ +H +++ E L++++K+Y + QKDI + L FQ
Sbjct: 1512 KESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQ-QKDIEHKELVQKLQHFQ 1570
Query: 291 TQPNNEVSAKHELEEQVKKLSHDTYS----LQLMAALLENECQILQQRVEILKELHHQKQ 346
+ + E EE++ L + YS L+ LE+ ++ + E LK L + +
Sbjct: 1571 ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1630
Query: 347 GTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKAC 406
K ++ K ++K + +M ++ +Q KGT S LN K
Sbjct: 1631 SESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGT--------ESHLSELNTKLQ 1682
Query: 407 NTQFNIHVARKALRGKMRSAS 427
+ +H+ + L+ S S
Sbjct: 1683 EREREVHILEEKLKSVESSQS 1703
Score = 42.7 bits (99), Expect = 6e-04
Identities = 68/333 (20%), Positives = 139/333 (41%), Gaps = 35/333 (10%)
Query: 81 KNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEMLS-----TNLPVSLAP-- 133
K+ E+K E K+L EE I D+ K K NE+++ TN +S
Sbjct: 1194 KSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHC 1253
Query: 134 EKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSL--APEKEDNEKKQQ 191
+ + K+ ++++T ++ A +R L + L+ + + EKE+ K +
Sbjct: 1254 QHRTTKVKEALLIKTCTVSELEAQ---LRQLTEEQNTLNISFQQATHQLEEKENQIKSMK 1310
Query: 192 MIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKN-------RLNVQEETMKIR 244
+E+ +E A + +K TQ +E ++N + ++E+ ++I
Sbjct: 1311 ADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1370
Query: 245 NNMEQL------LQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVS 298
+ +QL LQ + S++ +S L K Y + + ++ + + + T ++S
Sbjct: 1371 SLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKIS 1430
Query: 299 AKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINY 358
A ++++ K S Q +N + LQ ++E+ K EK QIN
Sbjct: 1431 ALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLEL-------KSKEAYEKDEQINL 1483
Query: 359 KQDKKNQKPSEAKKVEMYKQNKQAMKGTFWKKD 391
+++ +Q + K+ + K + K KK+
Sbjct: 1484 LKEELDQ---QNKRFDCLKGEMEDDKSKMEKKE 1513
Score = 42.0 bits (97), Expect = 0.001
Identities = 97/445 (21%), Positives = 187/445 (42%), Gaps = 75/445 (16%)
Query: 54 KNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKIT------EAKELFEETNITEDVS 107
K S + ++ KF N K+++ + + +E + EAK E N ++S
Sbjct: 934 KEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELS 993
Query: 108 AHKENIRGLDKINEMLSTNLP-VSLAPEK-EDNEKKQ-EMILETNITE--DVSAHKENIR 162
++ K+ EM N +S A + E N+K+Q E + E + E DV + E +
Sbjct: 994 QKEKQFNA--KMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWE--K 1049
Query: 163 GLDKINEMLSTNLPVSLAP-EKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLN 221
L++ E L + L E+E E KQ++++ E + +++ LN
Sbjct: 1050 KLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLN 1109
Query: 222 ETQQSQEKAKNRLN--VQEETMKIRNNMEQL-------LQEAEHWSKQHTELSKLIKSYQ 272
E Q+ ++ +N Q+ET K++ ++E+L L+E +Q EL L + +
Sbjct: 1110 ELQEQLKQKSAHVNSLAQDET-KLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDK 1168
Query: 273 KSQKDISETLGNNGVGFQTQPNNEVSAKHELEE---QVKKLSHDTYSLQL------MAAL 323
+ +++ L FQ+ ++ + LE+ + KKLS + ++QL AL
Sbjct: 1169 RKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE-LAIQLDICCKKTEAL 1227
Query: 324 LE---------------------NECQILQQRVE--------ILKELHHQ-KQGTLQEKP 353
LE + CQ +V+ + EL Q +Q T ++
Sbjct: 1228 LEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNT 1287
Query: 354 IQINYKQ------DKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLN--KKA 405
+ I+++Q +K+NQ S +E K+A++ + ++ + C+ KK
Sbjct: 1288 LNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1347
Query: 406 CNTQFN-IHVARKALRGKMRSASSL 429
+ N + + ++ L+ K SSL
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSL 1372
Score = 37.4 bits (85), Expect = 0.026
Identities = 70/348 (20%), Positives = 149/348 (42%), Gaps = 38/348 (10%)
Query: 63 QQTAQKFNNLLKEIKD---ILKNMA-GFEEKITEAKELFEETNITEDVSAHKENIRGLDK 118
Q+ ++ +N +KE ++ L+N + ++ K+ E N++ V + +E ++ L+
Sbjct: 1570 QELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLS--VKSKEEELKALE- 1626
Query: 119 INEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLP-- 176
+ L + LA K E+K I + +++ ++ +G + L+T L
Sbjct: 1627 --DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQER 1684
Query: 177 ---VSLAPEKEDNEKKQQM--IMENQNSENTA------QVFARDLVNRLEEKK--VLNET 223
V + EK + + Q ++ ++++N A + ++ V + E+K VL
Sbjct: 1685 EREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRN 1744
Query: 224 QQSQEKAKNRLNVQEET-----MKIRNNMEQLLQEAEHW-SKQHTELSK---LIKSYQKS 274
+EK R+ ++E ++R ++ L + EH +KQH + S L + ++
Sbjct: 1745 LTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEK 1804
Query: 275 QKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQR 334
K S + + + N + AK LE + +L +LE + + L
Sbjct: 1805 NKKYSLIVAQHVE--KEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSC 1862
Query: 335 VEILKELHHQKQGTLQEK--PIQINYKQDKKNQKPSEAKKVEMYKQNK 380
+ KE+H + L K +Q + D +N KP+E + +++K
Sbjct: 1863 LVRQKEVHRVEMEELTSKYEKLQALQQMDGRN-KPTELLEENTEEKSK 1909
Score = 36.6 bits (83), Expect = 0.045
Identities = 64/295 (21%), Positives = 111/295 (37%), Gaps = 55/295 (18%)
Query: 155 SAHKENIRGLDKINEMLSTNLPVSLAPEKED------NEKKQQMIMENQNSENTAQ---- 204
++ +E++ LD + S + P + E ED + K+Q+I + E +
Sbjct: 96 TSSRESLNRLDLDSSTASFDPPSDMDSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRG 155
Query: 205 -----VFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSK 259
V A ++ R E+KK+ QSQ+K+ R+ E +++ ++ LQ E +
Sbjct: 156 KYSELVTAYQMLQR-EKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQ--EEFDA 212
Query: 260 QHTELSKLIKSYQKSQKDISETLGNNGVGF-------QTQPNNEVSAKHE---------- 302
E + I Q + + L N + Q +P EV K E
Sbjct: 213 SLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVV 272
Query: 303 ------------------LEEQVKKLSHDTYSLQLMAALLENECQILQQRV-EILKELHH 343
E +K+ S + LL +E + LQ+++ E L+EL
Sbjct: 273 EDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEK 332
Query: 344 QKQGTLQEKPIQINYKQDKKNQ-KPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSL 397
K + EK I +D KN + E K + + K+ M T K+ L
Sbjct: 333 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL 387
Score = 32.7 bits (73), Expect = 0.65
Identities = 62/294 (21%), Positives = 119/294 (40%), Gaps = 49/294 (16%)
Query: 58 HQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLD 117
H+V ++ K+ L L+ M G + EL EE N E +H + L
Sbjct: 1870 HRVEMEELTSKYEKL-----QALQQMDGRNKPT----ELLEE-NTEEKSKSHLVQPKLLS 1919
Query: 118 KINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSA-HKENIRGLDKINEMLSTNLP 176
+ E +L LA + + +K + I+ + +D+ KE+ + L+ + +
Sbjct: 1920 NM-EAQHNDLEFKLAGAEREKQKLGKEIVR--LQKDLRMLRKEHQQELEILKKEYDQERE 1976
Query: 177 VSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQ-------QSQEK 229
+ E+ED E K ++ E Q+ ++ + K+ +N+ Q +S ++
Sbjct: 1977 EKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE 2036
Query: 230 AKNRL-----NVQEETMKIRNNMEQLL--QEAEHWSK---QHTELSKLIKSYQKSQKDIS 279
N+L ++ + E++L +E E +K T+L +L K YQ+ +
Sbjct: 2037 ETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ-E 2095
Query: 280 ETLGNNGV---GFQTQPNNEVS--------------AKHELEEQVKKLSHDTYS 316
E GN+ V QTQ + + H LE+++KK + Y+
Sbjct: 2096 ENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYA 2149
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 55.8 bits (133), Expect = 7e-08
Identities = 82/421 (19%), Positives = 181/421 (42%), Gaps = 59/421 (14%)
Query: 41 SHSPSSWGSLPFLKNSSHQVTEQQTAQ-KFNNLLKEIKDILKNMAGFEEKITEAKELF-- 97
S P+ S+P K+++ V++ ++ + NN L++I + + +AG EE+ + KE
Sbjct: 1806 STRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1865
Query: 98 ---EETNITEDVSAH-------KENIRGLDKINEMLSTNLP-----VSLAPEKEDNEKKQ 142
E+ + +S +E + ++ +N+ + L A E++D+ +++
Sbjct: 1866 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER 1925
Query: 143 EMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENT 202
M + + + +++ NE+L + + E E+KQQ++ E E+
Sbjct: 1926 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESE 1985
Query: 203 AQVFARDLVNRLEEKKVLNETQQSQEKAKNRLN---VQEETMKIRNNMEQLLQEAEHWSK 259
+ K+ L + Q +Q++ N+ + +QE + + ++QL ++ + +
Sbjct: 1986 IR------------KEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQE 2033
Query: 260 QHTELSKLIKSYQ----KSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTY 315
+ + L + +K+ + +SQKD+ T N + + A+ EL K L DT
Sbjct: 2034 KISALERTVKALEFVQTESQKDLEITKENLAQAVE----HRKKAQAEL-ASFKVLLDDTQ 2088
Query: 316 SLQLMAALLENECQILQQRVEILKELHHQKQGT---LQEKPIQINYKQDKKNQKPSEAKK 372
S ++L +++ KEL K+ +++K + + ++ +K + KK
Sbjct: 2089 S---------EAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKK 2139
Query: 373 VEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKK---ACNTQFNIHVARKALRGKMRSASSL 429
++ A++ + + + V LNKK Q N+ L +S SSL
Sbjct: 2140 --NMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL 2197
Query: 430 R 430
+
Sbjct: 2198 Q 2198
Score = 48.1 bits (113), Expect = 1e-05
Identities = 84/373 (22%), Positives = 160/373 (42%), Gaps = 98/373 (26%)
Query: 59 QVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEA---------KELFEETNIT-----E 104
Q + + T++ + + + I+ ++G EE I A KE+ E N+ E
Sbjct: 2364 QASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEE 2423
Query: 105 DVSAHKENIRGLDKINEMLST----------------NLPVSLAPEKED----------- 137
++ +EN + +DK N+++ T + S++ + D
Sbjct: 2424 NIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2483
Query: 138 NEKKQEMILETN-ITEDVSAH----KENIRGL-DKINEMLSTN--LPVSLAPEKED---- 185
E+ +ILE + + ++ +A KE IRGL ++++ S N L L +ED
Sbjct: 2484 EERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQV 2543
Query: 186 ---NEKKQQMIMENQNSENTAQVFARDLVN---RLEEKKVLNETQQSQEKAKNRLN-VQE 238
+ +Q+ ++E Q +N ++L N +LEEK L E++++ E + N +QE
Sbjct: 2544 ITIKDSQQKQLLEVQLQQN------KELENKYAKLEEK--LKESEEANEDLRRSFNALQE 2595
Query: 239 ETMKIRNNMEQLLQEAEHWSKQHT--------------------ELSKLIKSYQKSQKDI 278
E + +E L ++Q T E+ +L + SQK I
Sbjct: 2596 EKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRI 2655
Query: 279 SETLGNNGVGFQTQPNNEV-SAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRV-E 336
+E L V Q + +V + +L++++K L HD A ++ NE + ++RV E
Sbjct: 2656 AE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHD-------AGIMRNETETAEERVAE 2707
Query: 337 ILKELHHQKQGTL 349
+ ++L +Q L
Sbjct: 2708 LARDLVEMEQKLL 2720
Score = 47.4 bits (111), Expect = 3e-05
Identities = 66/314 (21%), Positives = 148/314 (47%), Gaps = 30/314 (9%)
Query: 49 SLPFLKNSSH---QVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEA-KELFEETNITE 104
+L F++ S ++T++ AQ + K ++ ++ +EA + L + + +
Sbjct: 2044 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKK 2103
Query: 105 DVSAHKENIRG-LDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSA-HKENIR 162
++ ++KE+++ + + +E L L A EK EKK N+ E + A +E +
Sbjct: 2104 ELQSNKESVKSQMKQKDEDLERRL--EQAEEKHLKEKK-------NMQEKLDALRREKVH 2154
Query: 163 GLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTA-QVFARDLVNRLEEK-KVL 220
+ I E + + K+D E +Q + EN +S T F + + + +++ +V+
Sbjct: 2155 LEETIGE-------IQVTLNKKDKEVQQ--LQENLDSTVTQLAAFTKSMSSLQDDRDRVI 2205
Query: 221 NETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISE 280
+E ++ + K + + +EE ++++ + +L++ H E K+ S + K I E
Sbjct: 2206 DEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE 2265
Query: 281 TLGNNGVGFQTQPNNEVSAKH-ELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILK 339
+ V Q + + + ++ EL Q+++ H +S Q A LE+E + L+ ++ L
Sbjct: 2266 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLS 2325
Query: 340 ---ELHHQKQGTLQ 350
E +++G L+
Sbjct: 2326 NSLEKCKEQKGNLE 2339
Score = 42.7 bits (99), Expect = 6e-04
Identities = 91/463 (19%), Positives = 185/463 (39%), Gaps = 59/463 (12%)
Query: 2 ASSAKSAEMPTISKTVNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQVT 61
A + K + T+ + N T + +E + I++ +I + SS + S V
Sbjct: 499 AENEKLSSQITLLEAQNRTGEADREVSE----ISIVDIANKRSSS------AEESGQDVL 548
Query: 62 EQQTAQKFNNL---LKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDK 118
E +QK L L E+K+ + +A + ++ + + + + + G+
Sbjct: 549 ENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAP 608
Query: 119 INEML---STNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLST-- 173
I + T L P +E + E E TE S E I D E+ ST
Sbjct: 609 IKMKVFLEDTGQDFPLMPNEESSLPAVEK--EQASTEHQSRTSEEISLNDAGVELKSTKQ 666
Query: 174 --NLPVSLAPE-----KEDNEKKQQMIMENQ-NSENTAQVFARDLVNRLEEKKVLNETQQ 225
+ +S P+ +++ E+ + I+E + N +++ ++L + +E LN Q
Sbjct: 667 DGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLN--QL 724
Query: 226 SQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNN 285
+E KN N + +QLL + + S TEL +K + + ++E
Sbjct: 725 IEEFKKNADNNSSAFTALSEERDQLLSQVKELSMV-TELRAQVKQLEMN---LAEAERQR 780
Query: 286 GVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQK 345
+ +++Q ++ + L EQ+ LS + S + +L+NE +Q + L
Sbjct: 781 RLDYESQTAHD----NLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSL 836
Query: 346 QGTLQEKPIQINYKQDK--------------KNQKPSEAKKVEMY----KQNKQAMKGTF 387
Q LQ K ++ ++ +QK E K++ K++ + ++ T
Sbjct: 837 QSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTI 896
Query: 388 WKKDRSCRSLDVCLNKKAC---NTQFNIHVARKALRGKMRSAS 427
+KD+ + + +K +F++ V K L+ ++ S
Sbjct: 897 EEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLS 939
Score = 42.4 bits (98), Expect = 8e-04
Identities = 58/295 (19%), Positives = 123/295 (41%), Gaps = 19/295 (6%)
Query: 57 SHQVTEQQTA-QKFNNLLKEIKDILKNM--------AGFEEKITEAK-ELFEETNITEDV 106
S Q++E++ A K + E +D++K + +E+I + + EL E E++
Sbjct: 1412 SGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEI 1471
Query: 107 SAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDK 166
E R +I L L KE+ ++E+ L E ++ ++
Sbjct: 1472 G---EESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS 1528
Query: 167 INEMLSTNLPVSLAPEKEDNEK----KQQMIMENQNSENTAQVFARDLVNRLEEKKVLNE 222
+ LA +E+ +K + ++ENQ+ ++ + L E+K+ L +
Sbjct: 1529 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVK 1588
Query: 223 TQQSQEKAK--NRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISE 280
+S + +K QE+ +++ E LLQ E+ S + + ++++ ++ ++++
Sbjct: 1589 EIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYG 1648
Query: 281 TLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRV 335
L + + A+ E+EE +K+ S Q LE E L+ V
Sbjct: 1649 KLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEV 1703
Score = 39.3 bits (90), Expect = 0.007
Identities = 71/328 (21%), Positives = 136/328 (41%), Gaps = 33/328 (10%)
Query: 70 NNLLKEIK----DILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEMLST 125
N ++E+K +L EE++++ + E + + HK L + E++ST
Sbjct: 108 NKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-----LQEKEELIST 162
Query: 126 NLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKED 185
L + + +Q T + E V ++ L + E +ST L L+ + +
Sbjct: 163 -----LQAQLTQAQAEQPAQSSTEMEEFVMMKQQ----LQEKEEFIST-LQAQLSQTQAE 212
Query: 186 NEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRN 245
+Q + ++ E ++ +L+ + + V E QQ + +L EE++ R
Sbjct: 213 QAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRA 272
Query: 246 NMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEE 305
+ LLQ+ ++Q + I S Q Q + N V + + + + K ELE
Sbjct: 273 QVVDLLQQELTAAEQRNQ----ILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEV 328
Query: 306 QVKKLSHDTYSLQLMAALLENECQILQQRVEI---LKELHHQKQGTLQEKPIQI--NYKQ 360
+KLS + M LLE Q Q + E+ L + + ++EK I K
Sbjct: 329 AERKLSFHNLQ-EEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKT 387
Query: 361 DKKNQKPSEAKKVEMYK----QNKQAMK 384
++ Q +A K + K +N+QA++
Sbjct: 388 GQELQSACDALKDQNSKLLQDKNEQAVQ 415
Score = 38.5 bits (88), Expect = 0.012
Identities = 81/395 (20%), Positives = 155/395 (39%), Gaps = 74/395 (18%)
Query: 86 FEEKITE-AKELFEETNITEDVSAHKENIRGL-----DKINEMLSTNLPVSLAPEKEDNE 139
+E+ + E AKE+ + E+ + +N ++ +++LS +S+ E
Sbjct: 707 YEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQV 766
Query: 140 KKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPV----SLAPEKEDNEKKQQMIME 195
K+ EM L A E R LD ++ NL SL+ E + + K +++
Sbjct: 767 KQLEMNL---------AEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQN 817
Query: 196 N------QNSENTAQVFARDLVNRLEEK----------------KVLNETQQSQEKAKNR 233
Q SE + + R L ++L+ K KV +Q +K
Sbjct: 818 ELDDVQLQFSEQSTLI--RSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEI 875
Query: 234 LNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQP 293
+ + ++ + ++E L Q E +Q TE+S S + ++E + GV +T
Sbjct: 876 TKMDQLLLEKKRDVETLQQTIEEKDQQVTEIS---FSMTEKMVQLNEEKFSLGVEIKTLK 932
Query: 294 NN-------EVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQ 346
E + K ++EE + S + M+ + + LQ ++LK+ + Q++
Sbjct: 933 EQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRK 992
Query: 347 GTLQEKPIQ---------------INYKQDKKNQKP---SEAKKVEMYKQNKQAMKGTFW 388
LQ I N K + K + P +E +VE K+NK+ +
Sbjct: 993 RKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVT 1052
Query: 389 KKDRSCRSLDVCLNKKACNTQFNIHVARKALRGKM 423
K C+ +++ L + + + RK L K+
Sbjct: 1053 SK---CQEIEIYLKQTISEKEVELQHIRKDLEEKL 1084
Score = 36.2 bits (82), Expect = 0.059
Identities = 57/283 (20%), Positives = 117/283 (41%), Gaps = 47/283 (16%)
Query: 116 LDKINEMLSTNLPVSLAPEKED---NEKKQEMILETNITEDVSAHKENIRGLDKINEMLS 172
LD++ +L LA KE N ++ ++ ET + + S + ++ L+K+N+ L
Sbjct: 2754 LDELKRKYDASLK-ELAQLKEQGLLNRERDALLSETAFSMN-STEENSLSHLEKLNQQLL 2811
Query: 173 TNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVL-NETQQ--SQEK 229
+ +E+ + + ++S N Q F++ + + E+ L NE ++ E+
Sbjct: 2812 SK-----------DEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEE 2860
Query: 230 AKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGF 289
K R Q T Q L++A S + +L+K + Q+
Sbjct: 2861 GKQRSAAQPSTSPAE---VQSLKKA--MSSLQNDRDRLLKELKNLQQQY----------- 2904
Query: 290 QTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILK------ELHH 343
Q N E++ H L+ Q+++ T + Q+M L E Q + L+ E+H
Sbjct: 2905 -LQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHE 2963
Query: 344 QKQG-----TLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQ 381
++ + +K Q+++ Q+ + S + + + K Q
Sbjct: 2964 RRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQ 3006
Score = 34.7 bits (78), Expect = 0.17
Identities = 54/279 (19%), Positives = 113/279 (40%), Gaps = 30/279 (10%)
Query: 70 NNLLKEIKDILKNMAGFEEKITE----AKELFEETNITEDVSAHKENIR--GLDKINEML 123
+ LLKE+K++ + ++ITE +L E + T+ +E +R L +E+
Sbjct: 2891 DRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELH 2950
Query: 124 STNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLD---------KINEMLSTN 174
+ S E K+Q ++ ++ + +S + IR L K+ +
Sbjct: 2951 QLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQAS 3010
Query: 175 LPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRL 234
S +P+ N + ++ Q +++ ++ ++L R+++ LN + KN L
Sbjct: 3011 PETSASPDGSQNLVYETELLRTQLNDSLKEIHQKEL--RIQQ---LNSNFSQLLEEKNTL 3065
Query: 235 NVQ--EETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLG----NNGVG 288
++Q + + +R N + H + L K ++ Q +I G NGV
Sbjct: 3066 SIQLCDTSQSLRENQQHYGDLLNHCA----VLEKQVQELQAGPLNIDVAPGAPQEKNGVH 3121
Query: 289 FQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENE 327
++ P + E ++L + + + LLE E
Sbjct: 3122 RKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEE 3160
Score = 34.3 bits (77), Expect = 0.22
Identities = 61/293 (20%), Positives = 118/293 (40%), Gaps = 30/293 (10%)
Query: 109 HKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKIN 168
+KE + L++ + ++ E E K ++ +N E K N+ G+ +
Sbjct: 2286 NKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2345
Query: 169 E-----------MLSTNLPVS---LAPEKEDNEKKQQMIME-NQNSENTAQVFARDLVNR 213
E L T+L S + E+ K+Q I+ E QV +L +
Sbjct: 2346 EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQ 2405
Query: 214 LEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSK----QHTELSKLIK 269
+++ E SQE+ +N + ++EE K + QL++ + K Q +L +K
Sbjct: 2406 HDKEIKELENLLSQEEEEN-IVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVK 2464
Query: 270 SYQKSQKDISETLGN---------NGVGFQTQPNNEVSAK-HELEEQVKKLSHDTYSLQL 319
S Q D +G+ + + + Q E +A+ ++L+E+++ L L
Sbjct: 2465 SMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNS 2524
Query: 320 MAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKK 372
A L+ E ++ + + + +Q L E +Q N + + K K E K
Sbjct: 2525 ENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLK 2577
Score = 30.8 bits (68), Expect = 2.5
Identities = 68/354 (19%), Positives = 141/354 (39%), Gaps = 61/354 (17%)
Query: 67 QKFNNLLKEIKDILKNMAG----FEEKITEAKELFEETNITEDVSAHKENIRGLDKINEM 122
++F L+K++ L++ + +I+E + + ++ IT + A + L K +
Sbjct: 1088 EQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL-ITSNTDASDGDSVALVKETVV 1146
Query: 123 LS---TNLPVSLAPEKEDN----EKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNL 175
+S T PE E+ EK++E L+ + E +++ K ++ K E +L
Sbjct: 1147 ISPPCTGSSEHWKPELEEKILALEKEKEQ-LQKKLQEALTSRKAILK---KAQEK-ERHL 1201
Query: 176 PVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLN 235
L +K+D + Q+ E Q+ EN ++ ++L + ++ + ++S + +
Sbjct: 1202 REELKQQKDDYNRLQEQFDE-QSKEN------ENIGDQLRQLQI--QVRESIDGKLPSTD 1252
Query: 236 VQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNN 295
QE E L + E Q S L + +D S G V
Sbjct: 1253 QQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLK 1312
Query: 296 EVSAKH----------------------ELEEQVKKLSHDTYSLQLMAALLENECQILQQ 333
E+ A+ +L+EQ+ K + SL+ ++ E + LQQ
Sbjct: 1313 EIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQ 1372
Query: 334 RVEI----------LKELH---HQKQGTLQEKPIQINYKQDKKNQKPSEAKKVE 374
++E L+EL + Q + +K ++Y + ++K + K++
Sbjct: 1373 KLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQ 1426
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 55.5 bits (132), Expect = 9e-08
Identities = 82/372 (22%), Positives = 156/372 (41%), Gaps = 53/372 (14%)
Query: 67 QKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNIT---EDVSAHKENIRGLDKINEML 123
+K N++L+E + FE AK +T I +S+ + +R L++ +ML
Sbjct: 354 EKENSMLRE-----EMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQML 408
Query: 124 STNLPVSLAPEKEDNEKKQEMILETN---ITEDVSAHKENIRGLDKINEML---STNLPV 177
+N +L+ E+ + E KQ + ++ + V KE + + E L + L
Sbjct: 409 KSN--GALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQA 466
Query: 178 SLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKK----VLNETQQSQEKAKN- 232
+ K++ +K ++ Q T L N+ + K VL E+ ++E+
Sbjct: 467 EIGQVKQELSRKDTELLALQTKLET-------LTNQFSDSKQHIEVLKESLTAKEQRAAI 519
Query: 233 --------RLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGN 284
RL ++E+ + +Q+ AE Q E+ L ++ ++ L
Sbjct: 520 LQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVN-VLQK 578
Query: 285 NGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQ 344
Q Q ++ L+E+VK L DT + LE ++ +E LKE Q
Sbjct: 579 KIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKE---Q 635
Query: 345 KQGTLQEKPIQI-NYKQDKKNQK-----------PSEAKKVEMYKQNKQAMKGTFWKKDR 392
+ +EK +I NYK+D K+ K EA +++ K++ ++ + KKD
Sbjct: 636 RDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDL-KEHASSLASSGLKKDS 694
Query: 393 SCRSLDVCLNKK 404
++L++ L +K
Sbjct: 695 RLKTLEIALEQK 706
Score = 42.4 bits (98), Expect = 8e-04
Identities = 50/297 (16%), Positives = 130/297 (43%), Gaps = 21/297 (7%)
Query: 62 EQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINE 121
E++ ++ +N K++KD+ + ++ + ++E +E ++ D+ H ++ +
Sbjct: 640 EREKQEEIDNYKKDLKDLKEKVSLLQGDLSE-----KEASLL-DLKEHASSLASSGLKKD 693
Query: 122 MLSTNLPVSLAPEKEDN-------EKKQEMILETNITEDVSAHKENIRGLDKINEMLSTN 174
L ++L +KE+ +K E LE + ++S + I+ L++ E+
Sbjct: 694 SRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS---DRIQHLER--EITRYK 748
Query: 175 LPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRL 234
S A + D + +EN+ ++ ++ + + + KKV N + Q + K
Sbjct: 749 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA 808
Query: 235 NVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPN 294
+ EE + +N+ Q+ + ++ + I+ +++ ++ + + + +
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDD---RIEELEEALRESVQITAEREMVLAQEES 865
Query: 295 NEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQE 351
+A+ ++EE + + L+ M A L + Q L ++ L L +++ L+E
Sbjct: 866 ARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEE 922
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 55.1 bits (131), Expect = 1e-07
Identities = 65/333 (19%), Positives = 159/333 (47%), Gaps = 30/333 (9%)
Query: 60 VTEQQTAQKFNNLLKEIKDILKN---MAGFEEKITEAKELFEETN-ITEDVSAHKENIRG 115
+++Q+ + N +K +++ KN + ++ T KEL + N +TE+
Sbjct: 548 LSQQELVPELENTIKNLQE--KNGVYLLSLSQRDTMLKELEGKINSLTEEKD-------- 597
Query: 116 LDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNL 175
D IN++ +++ + +K + E++ + L + + + + E + K+NE L+ L
Sbjct: 598 -DFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQ---KVNE-LTGGL 652
Query: 176 PVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLN 235
+L + ++++K ++++++ + +V + ++ + EE L+ ++ +
Sbjct: 653 EETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFL 712
Query: 236 VQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNN 295
Q+E + ++ ++ QL ++ + ++ L+KL+++ Q + + L GF + +
Sbjct: 713 SQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQL----YGFLKEMGS 768
Query: 296 EVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQ 355
EVS E ++ V L SL A + E +C + QR E + EL + + +E +Q
Sbjct: 769 EVSEDSEEKDVVNVLQAVGESL---AKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQ 825
Query: 356 I----NYKQDKKNQKPSEAKKVEMYKQNKQAMK 384
+ +D + +K K++E + K+A++
Sbjct: 826 CEELKSLLRDYEQEKVLLRKELEEIQSEKEALQ 858
Score = 43.1 bits (100), Expect = 5e-04
Identities = 76/344 (22%), Positives = 142/344 (41%), Gaps = 56/344 (16%)
Query: 54 KNSSHQVTEQQTA---QKFNNLLKEIKDILKNMAGFEEKITEAKELFEET--NITEDVSA 108
KN+ + EQ+ QK L +EI + ++ +EEK T+ K+L +T + + A
Sbjct: 1179 KNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQA 1238
Query: 109 HKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKIN 168
+++ L SL E E ++++ E + + + E +++ K KI+
Sbjct: 1239 ETDHL------------ILQASLKGELEASQQQVE-VYKIQLAE-ITSEKH------KIH 1278
Query: 169 EMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQE 228
E L T+ E+ Q+ + Q Q R + E+ V +E + +
Sbjct: 1279 EHLKTSA-----------EQHQRTLSAYQQRVTALQEECR--AAKAEQATVTSEFESYKV 1325
Query: 229 KAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVG 288
+ N L Q+ + E QE EH L LI + +D L N
Sbjct: 1326 RVHNVLKQQKNKSMSQAETEGAKQEREH-------LEMLIDQLKIKLQDSQNNLQINVSE 1378
Query: 289 FQTQPNNEVSAKHE-LEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQ--K 345
QT + ++H+ L E+ K+ +T S + A L E C I + + ++K H Q
Sbjct: 1379 LQT-----LQSEHDTLLERHNKMLQETVSKE--AELREKLCSIQSENM-MMKSEHTQTVS 1430
Query: 346 QGTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGTFWK 389
Q T Q + ++ +++ ++ + K VE +Q M+ ++
Sbjct: 1431 QLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQ 1474
Score = 42.7 bits (99), Expect = 6e-04
Identities = 76/359 (21%), Positives = 146/359 (40%), Gaps = 84/359 (23%)
Query: 74 KEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAP 133
+E+K +L++ +EK+ KEL E++ + KE ++ S L + A
Sbjct: 827 EELKSLLRDYE--QEKVLLRKEL-------EEIQSEKEALQ---------SDLLEMKNAN 868
Query: 134 EKEDNEKKQEMILETNITEDVSA---HKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQ 190
EK E + +I +++ S H E + K +E L L +KE +++
Sbjct: 869 EKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKP-----LLEQKELRDRRA 923
Query: 191 QMIMENQNSENTAQVFARDL--VNRLEEK------------KVLNETQQSQEKAKNRLNV 236
++I+ + + V L V LEEK + +N+ + KAK L+
Sbjct: 924 ELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDS 983
Query: 237 -QEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSY---------QKSQKDISETLGNNG 286
++ET ++ +E L E + S +L + +SY Q Q D+ + NN
Sbjct: 984 SRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANN- 1042
Query: 287 VGFQTQPNNEVSAKHELEEQVKKLSHDTY-----------------SLQLMAALLENE-C 328
+H +E+ ++L + T +LQ A LLE +
Sbjct: 1043 ------------FEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQIL 1090
Query: 329 QILQQRVEILKELHH---QKQGTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMK 384
++ + + + KEL QK+ ++E +N ++ + Q E K+++ Q + +K
Sbjct: 1091 EVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVK 1149
Score = 33.1 bits (74), Expect = 0.50
Identities = 50/263 (19%), Positives = 110/263 (41%), Gaps = 25/263 (9%)
Query: 140 KKQEMILE------TNITEDVSA--HKENIRGLDKINEMLSTNLPVSLAPEKEDNE---- 187
KKQ M+++ T + +++ K G I + L+ L L + E +
Sbjct: 35 KKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQCLS 94
Query: 188 -KKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNN 246
KK+ + M+ + ++ ++ D LE+ + N ++ + + V+ + + + N
Sbjct: 95 LKKENIKMKQEVEDSVTKM--GDAHKELEQSHI-NYVKEIENLKNELMAVRSKYSEDKAN 151
Query: 247 MEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGF-------QTQPNNEVSA 299
+++ L+EA + + +E K + + + K + E + GF Q Q +
Sbjct: 152 LQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDE 211
Query: 300 KHELEEQVKKL--SHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQIN 357
K E Q++ + ++ + + + +L E Q+ E +KEL Q + + +E +IN
Sbjct: 212 KKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEIN 271
Query: 358 YKQDKKNQKPSEAKKVEMYKQNK 380
+ K + + E Q K
Sbjct: 272 KLNELKENLVKQCEASEKNIQKK 294
>gi|151101140 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/286 (21%), Positives = 129/286 (45%), Gaps = 26/286 (9%)
Query: 72 LLKEIKDILKNMAGFEEKITEAKE-----LFEETNITEDVSAHK----ENIRGLDKINEM 122
LLK+IKD + +A E ++T+ KE + E + D+ H+ + + L K E
Sbjct: 308 LLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYKELKKREEH 367
Query: 123 LSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPE 182
+ T + E ++ E K++ +E NI + NI +++I+ + + L +
Sbjct: 368 MDTF--IETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQISSITNQELKMM---- 421
Query: 183 KEDNEKKQQMIMENQNSENTAQVFARDLVNRLE---EKKVLNETQQSQEK--AKNRLNVQ 237
++D K E Q S++TAQ D + RL+ +K L E++ ++E+ K+++
Sbjct: 422 QDDLNFKS---TEVQKSQSTAQNLTSD-IQRLQLDLQKMELLESKMTEEQHSLKSKIKQM 477
Query: 238 EETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISE--TLGNNGVGFQTQPNN 295
++I N++ L E K+ + ++ +++ + K I E + + Q Q N
Sbjct: 478 TTDLEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIMEKQNIEYEALKTQLQENE 537
Query: 296 EVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKEL 341
S LE + + L + ++++ A E + + K++
Sbjct: 538 THSQLTNLERKWQHLEQNNFAMKEFIATKSQESDYQPIKKNVTKQI 583
>gi|151105223 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/286 (21%), Positives = 129/286 (45%), Gaps = 26/286 (9%)
Query: 72 LLKEIKDILKNMAGFEEKITEAKE-----LFEETNITEDVSAHK----ENIRGLDKINEM 122
LLK+IKD + +A E ++T+ KE + E + D+ H+ + + L K E
Sbjct: 308 LLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYKELKKREEH 367
Query: 123 LSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPE 182
+ T + E ++ E K++ +E NI + NI +++I+ + + L +
Sbjct: 368 MDTF--IETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQISSITNQELKMM---- 421
Query: 183 KEDNEKKQQMIMENQNSENTAQVFARDLVNRLE---EKKVLNETQQSQEK--AKNRLNVQ 237
++D K E Q S++TAQ D + RL+ +K L E++ ++E+ K+++
Sbjct: 422 QDDLNFKS---TEVQKSQSTAQNLTSD-IQRLQLDLQKMELLESKMTEEQHSLKSKIKQM 477
Query: 238 EETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISE--TLGNNGVGFQTQPNN 295
++I N++ L E K+ + ++ +++ + K I E + + Q Q N
Sbjct: 478 TTDLEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIMEKQNIEYEALKTQLQENE 537
Query: 296 EVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKEL 341
S LE + + L + ++++ A E + + K++
Sbjct: 538 THSQLTNLERKWQHLEQNNFAMKEFIATKSQESDYQPIKKNVTKQI 583
>gi|151105229 coiled-coil domain containing 2 isoform a [Homo
sapiens]
Length = 600
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/286 (21%), Positives = 129/286 (45%), Gaps = 26/286 (9%)
Query: 72 LLKEIKDILKNMAGFEEKITEAKE-----LFEETNITEDVSAHK----ENIRGLDKINEM 122
LLK+IKD + +A E ++T+ KE + E + D+ H+ + + L K E
Sbjct: 308 LLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYKELKKREEH 367
Query: 123 LSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPE 182
+ T + E ++ E K++ +E NI + NI +++I+ + + L +
Sbjct: 368 MDTF--IETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQISSITNQELKMM---- 421
Query: 183 KEDNEKKQQMIMENQNSENTAQVFARDLVNRLE---EKKVLNETQQSQEK--AKNRLNVQ 237
++D K E Q S++TAQ D + RL+ +K L E++ ++E+ K+++
Sbjct: 422 QDDLNFKS---TEVQKSQSTAQNLTSD-IQRLQLDLQKMELLESKMTEEQHSLKSKIKQM 477
Query: 238 EETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISE--TLGNNGVGFQTQPNN 295
++I N++ L E K+ + ++ +++ + K I E + + Q Q N
Sbjct: 478 TTDLEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIMEKQNIEYEALKTQLQENE 537
Query: 296 EVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKEL 341
S LE + + L + ++++ A E + + K++
Sbjct: 538 THSQLTNLERKWQHLEQNNFAMKEFIATKSQESDYQPIKKNVTKQI 583
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 53.9 bits (128), Expect = 3e-07
Identities = 72/358 (20%), Positives = 152/358 (42%), Gaps = 37/358 (10%)
Query: 53 LKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHK-- 110
+K +Q ++ N L +++ + +E ++ E++ EE HK
Sbjct: 552 IKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLL 611
Query: 111 -ENIRGLDKINEM-----LSTNLPVSLAPEKEDNEKKQEMILE-TNITEDVSAHKENI-R 162
+G ++ E ++ + + +E EK + E T + +++ KE R
Sbjct: 612 KAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAER 671
Query: 163 GLDKIN--EMLSTNLPVSLAPEKEDNEKKQQ-----------MIMENQNSENTAQVFARD 209
L+K+ E S + L +E EK ++ + + Q+ E +V
Sbjct: 672 ELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQ 731
Query: 210 LVNRLEEKKVL-NETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLI 268
+ L +K+ L N Q+ +E+A + + E + N M+ ++ E + +E +KL
Sbjct: 732 IKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLA 791
Query: 269 KSYQ-------KSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYS----- 316
+ K+Q+++ L +TQ + +LEEQ++K+SH +S
Sbjct: 792 ANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRL 851
Query: 317 LQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVE 374
L+L L E + +Q++E+ ++L + Q +LQE+ Q+ Q + S+ ++ +
Sbjct: 852 LELETRLREVSLEHEEQKLELKRQL-TELQLSLQERESQLTALQAARAALESQLRQAK 908
Score = 37.0 bits (84), Expect = 0.035
Identities = 60/285 (21%), Positives = 117/285 (41%), Gaps = 42/285 (14%)
Query: 84 AGFEEKITEAKELFEETNITED-----VSAHKENI-RGLDKINEMLS--TNLPVSLAPEK 135
A E ++ +AK EET + ++AH++ I R D + + T+L L
Sbjct: 898 AALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLT 957
Query: 136 EDNEK--KQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMI 193
EDN + Q L + E A+ E ++ +++ + +E E++ Q+
Sbjct: 958 EDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHL-----------RREITEREMQLT 1006
Query: 194 MENQNSE---NTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQL 250
+ Q E T + +++ L E ++ E ++ L ++ + R Q
Sbjct: 1007 SQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQR 1066
Query: 251 LQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKK- 309
+ + E S+ + ++ +S Q + + E ++ + L+EQ K
Sbjct: 1067 MLDTEKQSRARAD-QRITESRQVVELAVKE-----------HKAEILALQQALKEQKLKA 1114
Query: 310 --LSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEK 352
LS L+ A+LE + LQQ++E +EL KQ L+E+
Sbjct: 1115 ESLSDKLNDLEKKHAMLEMNARSLQQKLETEREL---KQRLLEEQ 1156
Score = 33.1 bits (74), Expect = 0.50
Identities = 41/216 (18%), Positives = 91/216 (42%), Gaps = 24/216 (11%)
Query: 61 TEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFE--ETNITEDVSAHKENIRGLDK 118
+++QT + +++ + ++ +++ E + +E + + ++ S + +R L +
Sbjct: 1007 SQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQR 1066
Query: 119 INEMLSTNLPVSLAPEKEDNEKKQEMILETNITED--VSAHKENIRGLDKINEMLSTNLP 176
ML T EK+ + + I E+ + V HK I L + +
Sbjct: 1067 ---MLDT--------EKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAE 1115
Query: 177 VSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNV 236
SL+ + D EKK M+ N S R+L RL E++ + QQ + KN +
Sbjct: 1116 -SLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQA--KLQQQMDLQKNHI-- 1170
Query: 237 QEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQ 272
++ +++ L A+ + ++L +++ Q
Sbjct: 1171 ----FRLTQGLQEALDRADLLKTERSDLEYQLENIQ 1202
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 53.5 bits (127), Expect = 4e-07
Identities = 81/358 (22%), Positives = 153/358 (42%), Gaps = 51/358 (14%)
Query: 63 QQTAQKFNNLLKEIKDILKNMAGFEEKITEA-KELFEETNITEDVSAHKENIRG-LDKIN 120
+++ + L +E K++ + ++ E+I E K + E I + V K ++ L++
Sbjct: 1493 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAE 1552
Query: 121 EMLSTNLPVSLAPEKEDNEKKQEM---ILETNITEDVSAHKEN-IRGLDKIN-----EML 171
L L + E N+ K E+ I E + E++ K N IR ++ + E+
Sbjct: 1553 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKD--EEIDQMKRNHIRIVESMQSTLDAEIR 1610
Query: 172 STNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQ------- 224
S N + L + E + + ++ + + N ++ A L N + +L +TQ
Sbjct: 1611 SRNDAIRLKKKMEGDLNEMEIQLNHAN-----RMAAEALRNYRNTQAILKDTQLHLDDAL 1665
Query: 225 QSQEKAKNRLNV--------QEETMKIRNNMEQ-----------LLQEAEHWSKQHTELS 265
+SQE K +L + Q E ++R +EQ LL +E HT+ +
Sbjct: 1666 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT 1725
Query: 266 KLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHE------LEEQVKKLSHDTYSLQL 319
LI + +K + DIS+ G Q N E AK + E++KK + L+
Sbjct: 1726 SLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1785
Query: 320 MAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVEMYK 377
M LE + LQ R++ ++L K G Q + ++ ++ + + + + VE K
Sbjct: 1786 MKKNLEQTVKDLQHRLDEAEQL-ALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVK 1842
Score = 48.5 bits (114), Expect = 1e-05
Identities = 83/384 (21%), Positives = 153/384 (39%), Gaps = 62/384 (16%)
Query: 59 QVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFE-ETNITEDVSAHKENIRGLD 117
Q+ Q A + + ++K E KI E E E E I +++A K + D
Sbjct: 892 QLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLE--D 949
Query: 118 KINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVS------------------AHKE 159
+ +E+ + L K + EK N+TE+++ AH++
Sbjct: 950 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Query: 160 NIRGL----DKINEMLSTNLPVSLAPEKED------NEKKQQMIMENQNSE-----NTAQ 204
+ L DK+N + T + L + +D EKK +M +E + AQ
Sbjct: 1010 TLDDLQAEEDKVNTL--TKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067
Query: 205 VFARDLVN---RLEEKKVLNETQQS--QEKAKNR----LNVQEETMKIRNNMEQLLQEAE 255
D+ N +L+EK E + S Q K ++ + +Q++ +++ +E+L +E E
Sbjct: 1068 ESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127
Query: 256 HWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTY 315
+ K + ++ISE L G T E++ K E E Q K+ D
Sbjct: 1128 AERASRAKAEKQRSDLSRELEEISERL--EEAGGATSAQIEMNKKREAEFQ--KMRRD-- 1181
Query: 316 SLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAK-KVE 374
L A L++E L++ H L E+ + + K ++ SE K +++
Sbjct: 1182 ---LEEATLQHEA-----TAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233
Query: 375 MYKQNKQAMKGTFWKKDRSCRSLD 398
N + + ++ CR+L+
Sbjct: 1234 DLASNMETVSKAKGNLEKMCRALE 1257
Score = 37.4 bits (85), Expect = 0.026
Identities = 50/233 (21%), Positives = 102/233 (43%), Gaps = 52/233 (22%)
Query: 54 KNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEK----ITEAKELFEETNITEDVSAH 109
+N+S T+++ + + E++DI++ EEK IT+A + EE +D SAH
Sbjct: 1723 QNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAH 1782
Query: 110 KENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLD-KIN 168
E ++ NL ++ + ++ +++ L+ K+ I+ L+ ++
Sbjct: 1783 LERMK----------KNLEQTVKDLQHRLDEAEQLALKGG--------KKQIQKLEARVR 1824
Query: 169 EMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQE 228
E L E E +K+ ++ R E+KV T Q++E
Sbjct: 1825 E---------LEGEVESEQKRNVEAVKGL---------------RKHERKVKELTYQTEE 1860
Query: 229 KAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQ-HTELSKLIKSYQKSQKDISE 280
KN L +Q+ K++ ++ ++AE +Q + LSK +++ Q ++ E
Sbjct: 1861 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSK----FRRIQHELEE 1909
Score = 32.0 bits (71), Expect = 1.1
Identities = 42/205 (20%), Positives = 91/205 (44%), Gaps = 40/205 (19%)
Query: 182 EKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQS---QEKAKNRLNVQE 238
E+ +EK Q+I Q R + R+E +K++ + Q + +NV+
Sbjct: 778 EEMRDEKLAQLITRTQ-------AMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKH 830
Query: 239 -ETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEV 297
MK+ ++ LL+ AE E++ + + ++K+++++++T
Sbjct: 831 WPWMKLYFKIKPLLKSAE----TEKEMANMKEEFEKTKEELAKT---------------E 871
Query: 298 SAKHELEEQVKKLSHDTYSLQLMA-------ALLENEC-QILQQRVEILKELHHQKQGTL 349
+ + ELEE++ L + LQL A E C Q+++ ++++ ++ +
Sbjct: 872 AKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAE 931
Query: 350 QEKPI--QINYKQDKKNQKPSEAKK 372
E+ I ++ K+ K + SE KK
Sbjct: 932 DEEEINAELTAKKRKLEDECSELKK 956
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 53.1 bits (126), Expect = 5e-07
Identities = 87/417 (20%), Positives = 178/417 (42%), Gaps = 74/417 (17%)
Query: 47 WGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDV 106
W S +++ + E++ A + L++E +L+ + +++ E +E + +D
Sbjct: 60 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEY----EGYEVESSLKDA 115
Query: 107 SAHKE--NIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMI-LETNITEDVSAHKENIRG 163
S KE + L+ E L+ + ++E + E++ LE + E+ S H E
Sbjct: 116 SFEKEATEAQSLEATCEKLN----------RSNSELEDEILCLEKELKEEKSKHSEQDEL 165
Query: 164 LDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVN---RLEE--KK 218
+ I++ + + S + + + E K + N E ++ +D +N +L+E K+
Sbjct: 166 MADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL-KIAIKDALNENSQLQESQKQ 224
Query: 219 VLNETQQSQEKAKNRLNVQEETMK-IRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQ-K 276
+L E + +E+ + LN Q+ T + + + EQ+L + E K TE +K + +
Sbjct: 225 LLQEAEVWKEQV-SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGE 283
Query: 277 DISE---------TLGNNGVGFQTQPNNEVS----------------------------- 298
DI++ + NG P +
Sbjct: 284 DITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEV 343
Query: 299 --AKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEK-PIQ 355
K EL E +K L + SLQ ENE Q LQQ+++++ EL+ + + L K ++
Sbjct: 344 DKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE 403
Query: 356 INYKQDKK------NQKPSEA-KKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKA 405
NY+ +K+ ++K S A +++E Y++ + ++ + S + + KKA
Sbjct: 404 ENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKA 460
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 53.1 bits (126), Expect = 5e-07
Identities = 87/417 (20%), Positives = 178/417 (42%), Gaps = 74/417 (17%)
Query: 47 WGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDV 106
W S +++ + E++ A + L++E +L+ + +++ E +E + +D
Sbjct: 60 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEY----EGYEVESSLKDA 115
Query: 107 SAHKE--NIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMI-LETNITEDVSAHKENIRG 163
S KE + L+ E L+ + ++E + E++ LE + E+ S H E
Sbjct: 116 SFEKEATEAQSLEATCEKLN----------RSNSELEDEILCLEKELKEEKSKHSEQDEL 165
Query: 164 LDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVN---RLEE--KK 218
+ I++ + + S + + + E K + N E ++ +D +N +L+E K+
Sbjct: 166 MADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL-KIAIKDALNENSQLQESQKQ 224
Query: 219 VLNETQQSQEKAKNRLNVQEETMK-IRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQ-K 276
+L E + +E+ + LN Q+ T + + + EQ+L + E K TE +K + +
Sbjct: 225 LLQEAEVWKEQV-SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGE 283
Query: 277 DISE---------TLGNNGVGFQTQPNNEVS----------------------------- 298
DI++ + NG P +
Sbjct: 284 DITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEV 343
Query: 299 --AKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEK-PIQ 355
K EL E +K L + SLQ ENE Q LQQ+++++ EL+ + + L K ++
Sbjct: 344 DKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE 403
Query: 356 INYKQDKK------NQKPSEA-KKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKA 405
NY+ +K+ ++K S A +++E Y++ + ++ + S + + KKA
Sbjct: 404 ENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKA 460
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 53.1 bits (126), Expect = 5e-07
Identities = 87/417 (20%), Positives = 178/417 (42%), Gaps = 74/417 (17%)
Query: 47 WGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDV 106
W S +++ + E++ A + L++E +L+ + +++ E +E + +D
Sbjct: 31 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEY----EGYEVESSLKDA 86
Query: 107 SAHKE--NIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMI-LETNITEDVSAHKENIRG 163
S KE + L+ E L+ + ++E + E++ LE + E+ S H E
Sbjct: 87 SFEKEATEAQSLEATCEKLN----------RSNSELEDEILCLEKELKEEKSKHSEQDEL 136
Query: 164 LDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVN---RLEE--KK 218
+ I++ + + S + + + E K + N E ++ +D +N +L+E K+
Sbjct: 137 MADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL-KIAIKDALNENSQLQESQKQ 195
Query: 219 VLNETQQSQEKAKNRLNVQEETMK-IRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQ-K 276
+L E + +E+ + LN Q+ T + + + EQ+L + E K TE +K + +
Sbjct: 196 LLQEAEVWKEQV-SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGE 254
Query: 277 DISE---------TLGNNGVGFQTQPNNEVS----------------------------- 298
DI++ + NG P +
Sbjct: 255 DITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEV 314
Query: 299 --AKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEK-PIQ 355
K EL E +K L + SLQ ENE Q LQQ+++++ EL+ + + L K ++
Sbjct: 315 DKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE 374
Query: 356 INYKQDKK------NQKPSEA-KKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKA 405
NY+ +K+ ++K S A +++E Y++ + ++ + S + + KKA
Sbjct: 375 ENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKA 431
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 53.1 bits (126), Expect = 5e-07
Identities = 87/417 (20%), Positives = 178/417 (42%), Gaps = 74/417 (17%)
Query: 47 WGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDV 106
W S +++ + E++ A + L++E +L+ + +++ E +E + +D
Sbjct: 48 WRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEY----EGYEVESSLKDA 103
Query: 107 SAHKE--NIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMI-LETNITEDVSAHKENIRG 163
S KE + L+ E L+ + ++E + E++ LE + E+ S H E
Sbjct: 104 SFEKEATEAQSLEATCEKLN----------RSNSELEDEILCLEKELKEEKSKHSEQDEL 153
Query: 164 LDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVN---RLEE--KK 218
+ I++ + + S + + + E K + N E ++ +D +N +L+E K+
Sbjct: 154 MADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERL-KIAIKDALNENSQLQESQKQ 212
Query: 219 VLNETQQSQEKAKNRLNVQEETMK-IRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQ-K 276
+L E + +E+ + LN Q+ T + + + EQ+L + E K TE +K + +
Sbjct: 213 LLQEAEVWKEQV-SELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGE 271
Query: 277 DISE---------TLGNNGVGFQTQPNNEVS----------------------------- 298
DI++ + NG P +
Sbjct: 272 DITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEV 331
Query: 299 --AKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEK-PIQ 355
K EL E +K L + SLQ ENE Q LQQ+++++ EL+ + + L K ++
Sbjct: 332 DKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVE 391
Query: 356 INYKQDKK------NQKPSEA-KKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKA 405
NY+ +K+ ++K S A +++E Y++ + ++ + S + + KKA
Sbjct: 392 ENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKA 448
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 52.8 bits (125), Expect = 6e-07
Identities = 71/287 (24%), Positives = 130/287 (45%), Gaps = 35/287 (12%)
Query: 59 QVTE--QQTAQKFNNLLKEIKDILKNMAGFEEKI----TEAKELFEETNITEDVSAHKEN 112
QVTE +Q + + K IK A ++E++ EA+ L EE D+ +E
Sbjct: 217 QVTESLKQVQLERDEYAKHIKG---ERARWQERMWKMSVEARTLKEEKK--RDIHRIQEL 271
Query: 113 IRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAH-KENIRGLD-KINEM 170
R L ++ ++ P SLAP + +Q +D + H ++ + GL+ K+
Sbjct: 272 ERSLSELKNQMAK--PPSLAPPAVTSVVEQ--------LQDEAKHLRQEVEGLEGKLQSQ 321
Query: 171 LSTNLPVSLAP--EKEDNEKKQQMIMENQNSENTAQVFARDLVNRL-EEKKVLNETQQSQ 227
+ N +SL +K+ +++++M+ E + Q + RL E++K L E +
Sbjct: 322 VENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERL 381
Query: 228 EKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGV 287
K + RL QEE ++R E+L ++ + Q L K + QK ++ ++ + +
Sbjct: 382 RKQEQRLRKQEE--RLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439
Query: 288 GFQTQP-------NNEVSAKHELEEQVKKLSHDTYSLQLMAALLENE 327
+P NNE + +LE+QVK+L L AA +N+
Sbjct: 440 KQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQ 486
Score = 39.7 bits (91), Expect = 0.005
Identities = 78/387 (20%), Positives = 151/387 (39%), Gaps = 63/387 (16%)
Query: 40 GSHSP--SSWGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELF 97
G HSP S + L SS VT Q + +L ++ K + E ++ EAK+
Sbjct: 62 GGHSPGDSQYQELAVALESS-SVTISQLNENIESLKQQKKQV-------EHQLEEAKKTN 113
Query: 98 EETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAH 157
E + + NI L+K + L T L + + E+ +++ +
Sbjct: 114 NEIHKAQMERLETINILTLEKAD--LKTTLYHTKRAARHFEEESKDLAGRLQYS------ 165
Query: 158 KENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEK 217
L +I E+ VS ++ED + + ++ + T + R L+N +
Sbjct: 166 ------LQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRLQQTIK--ERALLNAHVTQ 217
Query: 218 KVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKD 277
+ Q E+ + +++ E + + M ++ EA + E + I Q+ ++
Sbjct: 218 VTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKE---EKKRDIHRIQELERS 274
Query: 278 ISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSL-----------QLMAALLEN 326
+SE P S +L+++ K L + L Q ++ L +
Sbjct: 275 LSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKE 334
Query: 327 ECQILQQRVEILKELHHQK-----------------QGTLQEKPIQINYKQDKKNQKPSE 369
+ Q LQ++ E+L+E Q+ Q TLQE+ ++ KQ+++ +K E
Sbjct: 335 QKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLR-KQEQRLRKQEE 393
Query: 370 AKKVEMYKQNKQA-----MKGTFWKKD 391
+ E + KQ + WKK+
Sbjct: 394 RLRKEEERLQKQEKRLWDQEERLWKKE 420
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 52.8 bits (125), Expect = 6e-07
Identities = 69/326 (21%), Positives = 139/326 (42%), Gaps = 39/326 (11%)
Query: 120 NEMLSTNLPVSLA----PEKEDNEKKQEMILETN----ITEDVSAHKENIRGLDKINEML 171
++M S++ PV EK + ++Q L T +T+ S H E + K++ +
Sbjct: 218 DKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLE 277
Query: 172 STNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAK 231
S + P I+E Q A+V A+D V R E K+ + EK +
Sbjct: 278 SAQQQAASVP-----------ILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQ 326
Query: 232 NRLNVQEETMKIRNNMEQLLQEAEHWSKQHTE----LSKLIKSYQKSQKDISETLGNNGV 287
+ +EE +K++ ++ + ++ + +Q E +L K++Q+ +K ++E L
Sbjct: 327 SLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKL----- 381
Query: 288 GFQTQPNNEVSAKHE-LEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQ 346
+V A+ E LE + + LQ L ++E +IL++++ LKE ++ +
Sbjct: 382 -------EKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGK 434
Query: 347 GTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAM---KGTFWKKDRSCRSLDVCLNK 403
L+ ++ + + + K+E +NK + K + ++R + N+
Sbjct: 435 EKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNE 494
Query: 404 KACNTQFNIHVARKALRGKMRSASSL 429
+ Q I +R LR + S L
Sbjct: 495 RLDLCQQEIESSRVELRSLEKIISQL 520
Score = 51.6 bits (122), Expect = 1e-06
Identities = 74/342 (21%), Positives = 141/342 (41%), Gaps = 65/342 (19%)
Query: 56 SSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRG 115
SS + Q+ ++I+ + N+ EKI A E ++ ++ + HKE +
Sbjct: 714 SSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQ----HKEMEKQ 769
Query: 116 LDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNL 175
++++ L EK+D + K++ + + +D+ + ++ LD++ L
Sbjct: 770 IERLEAQL----------EKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRL-------L 812
Query: 176 PVSLAPEKEDNEKKQQMI--MENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNR 233
S K++N KK + + ++NQ SE T +V D +
Sbjct: 813 TESKGEMKKENMKKDEALKALQNQVSEETIKVRQLD----------------------SA 850
Query: 234 LNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQP 293
L + +E + + N QL E + KQ + S+ + QK K + +L Q
Sbjct: 851 LEICKEELVLHLN--QLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSL-------QETS 901
Query: 294 NNEVSAKHELEEQVKKLSHDTY---SLQLMAALLENECQILQQRVEILKELHHQKQGTLQ 350
V +H L++Q + L +T L+ LE + L+Q ++ +E +K ++
Sbjct: 902 EQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKME 961
Query: 351 EKPIQINYKQDKKNQKPSEAK------KVEM--YKQNKQAMK 384
EK ++ D K QK E K+EM YK+ M+
Sbjct: 962 EKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKME 1003
Score = 50.8 bits (120), Expect = 2e-06
Identities = 70/360 (19%), Positives = 160/360 (44%), Gaps = 18/360 (5%)
Query: 53 LKNSSHQVTEQQTAQKFNNLLKEI-KDILKNMAGFEEKITEAKELFEETNITEDVSAHKE 111
+K HQV E Q + + K+ K+ + + G EE T+ ++ E + + AH+
Sbjct: 609 VKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRT 668
Query: 112 NIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMI-LETNITEDVSAHKENIRGLDKINEM 170
+ L I E L S E E +K +++ LE + E + A+ ++ +
Sbjct: 669 SQFQL--IQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQE 726
Query: 171 LSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLE--EKKVLNETQQSQE 228
L + E N + +++ + + ++ +++ ++E E ++ + QQ +E
Sbjct: 727 LMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKE 786
Query: 229 KAKNRLNVQEETMKIRNNME---QLLQEAE-HWSKQHTELSKLIKSYQK--SQKDISETL 282
+ K +Q++ + ++++E +LL E++ K++ + + +K+ Q S++ I
Sbjct: 787 QEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQ 846
Query: 283 GNNGVGFQTQP-----NNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEI 337
++ + + N K + E+Q+KK S + Y LQ + + Q ++ I
Sbjct: 847 LDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVI 906
Query: 338 LKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVEM-YKQNKQAMKGTFWKKDRSCRS 396
L+ Q+Q LQ++ I+ +D + + + K+E ++ +++ K + C S
Sbjct: 907 LQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCES 966
Score = 42.7 bits (99), Expect = 6e-04
Identities = 63/323 (19%), Positives = 131/323 (40%), Gaps = 47/323 (14%)
Query: 59 QVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDK 118
++ Q ++ + + KEI + ++ +++ + ++T ++ ++ L+K
Sbjct: 989 KIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKT--ELEKKTNAVKELEK 1046
Query: 119 INEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLST----- 173
+ T L +L +K+E +LET + K +R L ++ ++L
Sbjct: 1047 LQHSTETELTEAL--------QKRE-VLETELQNAHGELKSTLRQLQELRDVLQKAQLSL 1097
Query: 174 --------NLPVSLAPEKEDNEKKQQMIMENQNS---------ENTAQVFARDLVNR--- 213
+L L K + E K+Q ++E + + AQV D+ R
Sbjct: 1098 EEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHR 1157
Query: 214 --LEEKKV-LNETQQSQEKAKNRLNVQEETM--KIRNNMEQLLQEAEHWSKQHTELSKLI 268
+E+K + L T + E N Q E++ K++N EQL ++ + E+S+L
Sbjct: 1158 GEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLK 1217
Query: 269 KSYQKSQ---KDISETLGNNGVGFQTQPNNEVSAKHEL---EEQVKKLSHDTYSLQLMAA 322
K +++Q K++ + TQ + EL EQV+ + +
Sbjct: 1218 KEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQV 1277
Query: 323 LLENECQILQQRVEILKELHHQK 345
+ E + L +E +K+L +K
Sbjct: 1278 QAQREIERLSSELEDMKQLSKEK 1300
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 52.8 bits (125), Expect = 6e-07
Identities = 71/287 (24%), Positives = 130/287 (45%), Gaps = 35/287 (12%)
Query: 59 QVTE--QQTAQKFNNLLKEIKDILKNMAGFEEKI----TEAKELFEETNITEDVSAHKEN 112
QVTE +Q + + K IK A ++E++ EA+ L EE D+ +E
Sbjct: 217 QVTESLKQVQLERDEYAKHIKG---ERARWQERMWKMSVEARTLKEEKK--RDIHRIQEL 271
Query: 113 IRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAH-KENIRGLD-KINEM 170
R L ++ ++ P SLAP + +Q +D + H ++ + GL+ K+
Sbjct: 272 ERSLSELKNQMAE--PPSLAPPAVTSVVEQ--------LQDEAKHLRQEVEGLEGKLQSQ 321
Query: 171 LSTNLPVSLAP--EKEDNEKKQQMIMENQNSENTAQVFARDLVNRL-EEKKVLNETQQSQ 227
+ N +SL +K+ +++++M+ E + Q + RL E++K L E +
Sbjct: 322 VENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERL 381
Query: 228 EKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGV 287
K + RL QEE ++R E+L ++ + Q L K + QK ++ ++ + +
Sbjct: 382 RKQEQRLRKQEE--RLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439
Query: 288 GFQTQP-------NNEVSAKHELEEQVKKLSHDTYSLQLMAALLENE 327
+P NNE + +LE+QVK+L L AA +N+
Sbjct: 440 KQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQ 486
Score = 38.5 bits (88), Expect = 0.012
Identities = 81/393 (20%), Positives = 150/393 (38%), Gaps = 75/393 (19%)
Query: 40 GSHSP--SSWGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELF 97
G HSP S + L SS VT Q + +L ++ K + E ++ EAK+
Sbjct: 62 GCHSPGDSQYQELAVALESS-SVTISQLNENIESLKQQKKQV-------EHQLEEAKKTN 113
Query: 98 EETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAH 157
E + + NI L+K + L T L + + E+ +++ +
Sbjct: 114 NEIHKAQMERLETINILTLEKAD--LKTTLYHTKRAARHFEEESKDLAGRLQYS------ 165
Query: 158 KENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEK 217
L +I E+ VS ++ED ++S V R L ++E+
Sbjct: 166 ------LQRIQELERALCAVSTQQQEED-----------RSSSCREAVLQRWLQQTIKER 208
Query: 218 KVLNE--TQQSQEKAKNRLNVQEETMKIRNN----MEQLLQEAEHWSKQHTELSKLIKSY 271
+LN TQ ++ + +L E I+ E++ + + E + I
Sbjct: 209 ALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRI 268
Query: 272 QKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSL-----------QLM 320
Q+ ++ +SE P S +L+++ K L + L Q +
Sbjct: 269 QELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQAL 328
Query: 321 AALLENECQILQQRVEILKELHHQK-----------------QGTLQEKPIQINYKQDKK 363
+ L + + Q LQ++ E+L+E Q+ Q TLQE+ ++ KQ+++
Sbjct: 329 SLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR-KQEQR 387
Query: 364 NQKPSEAKKVEMYKQNKQA-----MKGTFWKKD 391
+K E + E + KQ + WKK+
Sbjct: 388 LRKQEERLRKEEERLQKQEKRLWDQEERLWKKE 420
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 52.4 bits (124), Expect = 8e-07
Identities = 71/287 (24%), Positives = 129/287 (44%), Gaps = 35/287 (12%)
Query: 59 QVTE--QQTAQKFNNLLKEIKDILKNMAGFEEKI----TEAKELFEETNITEDVSAHKEN 112
QVTE +Q + + K IK A ++E++ EA+ L EE D+ +E
Sbjct: 217 QVTESLKQVQLERDEYAKHIKG---ERARWQERMWKMSVEARTLKEEKK--RDIHRIQEL 271
Query: 113 IRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAH-KENIRGLD-KINEM 170
R L ++ ++ P SLAP + +Q +D + H ++ + GL+ K+
Sbjct: 272 ERSLSELKNQMAE--PPSLAPPAVTSVVEQ--------LQDEAKHLRQEVEGLEGKLQSQ 321
Query: 171 LSTNLPVSLAP--EKEDNEKKQQMIMENQNSENTAQVFARDLVNRL-EEKKVLNETQQSQ 227
+ N +SL +K+ +++++M+ E + Q + RL E++K L E +
Sbjct: 322 VENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERL 381
Query: 228 EKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGV 287
K + RL QEE ++R E+L ++ + Q L K + QK ++ ++ + +
Sbjct: 382 RKQEQRLRKQEE--RLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439
Query: 288 GFQTQP-------NNEVSAKHELEEQVKKLSHDTYSLQLMAALLENE 327
+P NNE + +LE+QVK+L L AA N+
Sbjct: 440 KQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQ 486
Score = 38.9 bits (89), Expect = 0.009
Identities = 75/388 (19%), Positives = 149/388 (38%), Gaps = 65/388 (16%)
Query: 40 GSHSPSSWGSLPFLKNSSHQ---VTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKEL 96
G HSP +S +Q V + ++ N L + I+ + + E ++ EAK+
Sbjct: 62 GGHSPG---------DSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKT 112
Query: 97 FEETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSA 156
E + + NI L+K + L T L + + E+ +++ +
Sbjct: 113 NNEIHKAQMEQLETINILTLEKAD--LKTTLYHTKRAARHFEEESKDLAGRLQYS----- 165
Query: 157 HKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEE 216
L I E+ VS ++ED + + + + T + R L+N
Sbjct: 166 -------LQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRLQQTIK--ERALLNAHVT 216
Query: 217 KKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQK 276
+ + Q E+ + +++ E + + M ++ EA + E + I Q+ ++
Sbjct: 217 QVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKE---EKKRDIHRIQELER 273
Query: 277 DISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSL-----------QLMAALLE 325
+SE P S +L+++ K L + L Q ++ L +
Sbjct: 274 SLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSK 333
Query: 326 NECQILQQRVEILKELHHQK-----------------QGTLQEKPIQINYKQDKKNQKPS 368
+ Q LQ++ E+L+E Q+ Q TLQE+ ++ KQ+++ +K
Sbjct: 334 EQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR-KQEQRLRKQE 392
Query: 369 EAKKVEMYKQNKQA-----MKGTFWKKD 391
E + E + KQ + WKK+
Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKE 420
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 52.4 bits (124), Expect = 8e-07
Identities = 71/287 (24%), Positives = 129/287 (44%), Gaps = 35/287 (12%)
Query: 59 QVTE--QQTAQKFNNLLKEIKDILKNMAGFEEKI----TEAKELFEETNITEDVSAHKEN 112
QVTE +Q + + K IK A ++E++ EA+ L EE D+ +E
Sbjct: 217 QVTESLKQVQLERDEYAKHIKG---ERARWQERMWKMSVEARTLKEEKK--RDIHRIQEL 271
Query: 113 IRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAH-KENIRGLD-KINEM 170
R L ++ ++ P SLAP + +Q +D + H ++ + GL+ K+
Sbjct: 272 ERSLSELKNQMAE--PPSLAPPAVTSVVEQ--------LQDEAKHLRQEVEGLEGKLQSQ 321
Query: 171 LSTNLPVSLAP--EKEDNEKKQQMIMENQNSENTAQVFARDLVNRL-EEKKVLNETQQSQ 227
+ N +SL +K+ +++++M+ E + Q + RL E++K L E +
Sbjct: 322 VENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERL 381
Query: 228 EKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGV 287
K + RL QEE ++R E+L ++ + Q L K + QK ++ ++ + +
Sbjct: 382 RKQEQRLRKQEE--RLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439
Query: 288 GFQTQP-------NNEVSAKHELEEQVKKLSHDTYSLQLMAALLENE 327
+P NNE + +LE+QVK+L L AA N+
Sbjct: 440 KQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQ 486
Score = 39.7 bits (91), Expect = 0.005
Identities = 75/388 (19%), Positives = 150/388 (38%), Gaps = 65/388 (16%)
Query: 40 GSHSPSSWGSLPFLKNSSHQ---VTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKEL 96
G HSP +S +Q V + ++ N L + I+ + + E ++ EAK+
Sbjct: 62 GGHSPG---------DSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKT 112
Query: 97 FEETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSA 156
E + + NI L+K + L T L + + E+ +++ +
Sbjct: 113 NNEIHKAQMEQLETINILTLEKAD--LKTTLYHTKRAARHFEEESKDLAGRLQYS----- 165
Query: 157 HKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEE 216
L +I E+ VS ++ED + + + + T + R L+N
Sbjct: 166 -------LQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQQTIK--ERALLNAHVT 216
Query: 217 KKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQK 276
+ + Q E+ + +++ E + + M ++ EA + E + I Q+ ++
Sbjct: 217 QVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKE---EKKRDIHRIQELER 273
Query: 277 DISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSL-----------QLMAALLE 325
+SE P S +L+++ K L + L Q ++ L +
Sbjct: 274 SLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSK 333
Query: 326 NECQILQQRVEILKELHHQK-----------------QGTLQEKPIQINYKQDKKNQKPS 368
+ Q LQ++ E+L+E Q+ Q TLQE+ ++ KQ+++ +K
Sbjct: 334 EQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLR-KQEQRLRKQE 392
Query: 369 EAKKVEMYKQNKQA-----MKGTFWKKD 391
E + E + KQ + WKK+
Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKE 420
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 52.4 bits (124), Expect = 8e-07
Identities = 64/272 (23%), Positives = 113/272 (41%), Gaps = 50/272 (18%)
Query: 63 QQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEM 122
Q Q+ N + D + + G EEK++ + +E T ++ + N RG D+++++
Sbjct: 944 QGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVN-RGRDQVDQL 1002
Query: 123 LSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPE 182
+ E++ E + +D+ K + L++ N+ L T L S +
Sbjct: 1003 ------------------RTELMQERSARQDLECDKIS---LERQNKDLKTRLASSEGFQ 1041
Query: 183 KEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMK 242
K Q +E+QN Q+ L EK VL T + E+ L++Q E
Sbjct: 1042 KPSASLSQ---LESQN-----QLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIE--- 1090
Query: 243 IRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHE 302
E +H + Q +LS +K+ K Q D +E G + + EV +HE
Sbjct: 1091 ---------DERQHVNDQKDQLSLRVKAL-KRQVDEAEEEIERLDGLRKKAQREVEEQHE 1140
Query: 303 LEEQ----VKKLSHDTY---SLQLMAALLENE 327
+ EQ +K L D++ S + L+NE
Sbjct: 1141 VNEQLQARIKSLEKDSWRKASRSAAESALKNE 1172
Score = 33.1 bits (74), Expect = 0.50
Identities = 60/314 (19%), Positives = 125/314 (39%), Gaps = 48/314 (15%)
Query: 75 EIKDILKNMAGFEE-KITEAKELFEETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAP 133
E+++ LK++ G E K K+L E + E+V K+ + ++ E T L +L
Sbjct: 447 ELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKE 506
Query: 134 EKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMI 193
E +++ E ++ + E +R + + +
Sbjct: 507 EVASRDQEVE-----HVRQQYQRDTEQLR-------------------RSMQDATQDHAV 542
Query: 194 MENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQE 253
+E + + +A V R L LEE S+E + Q+ +R ++LLQ
Sbjct: 543 LEAERQKMSALV--RGLQRELEE--------TSEETGHWQSMFQKNKEDLRATKQELLQL 592
Query: 254 AEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHEL--EEQVKKLS 311
+ EL + I+ Q+ + + G+ EV K L +E++K+L
Sbjct: 593 RMEKEEMEEELGEKIEVLQRELEQARASAGDT-------RQVEVLKKELLRTQEELKELQ 645
Query: 312 HDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAK 371
+ S ++ + E L++++ +L+ + + L+E+ +Q+ + Q EA
Sbjct: 646 AERQSQEVAGRHRDRE---LEKQLAVLR-VEADRGRELEEQNLQLQKTLQQLRQDCEEAS 701
Query: 372 KVEMYKQNKQAMKG 385
K +M + + + G
Sbjct: 702 KAKMVAEAEATVLG 715
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 52.0 bits (123), Expect = 1e-06
Identities = 63/285 (22%), Positives = 119/285 (41%), Gaps = 31/285 (10%)
Query: 62 EQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINE 121
EQ+ K L+ +++ K M F +K + L + N + R +I E
Sbjct: 240 EQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNA--------QLSRRTQQIQE 291
Query: 122 MLSTNLPVSLAP-EKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLA 180
L + + A EKED ++ + + DV+ K+ I ++ L + L
Sbjct: 292 ELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLR 351
Query: 181 PEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEET 240
E ++ +K++ + S ARD RL + + QQ QEK + QEE+
Sbjct: 352 EEAKEMWEKREAEWARERS-------ARD---RLMSEVLTGRQQQIQEKIEQNRRAQEES 401
Query: 241 MKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAK 300
+K R + + L+E +++ E S+ +KS +K + + ++ ++ E
Sbjct: 402 LKHREQLIRNLEEVRELARREKEESEKLKSARKQELE-AQVAERRLQAWEADQQEE---- 456
Query: 301 HELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQK 345
E EE+ +++ QL ALL+ E + + ++ K H K
Sbjct: 457 -EEEEEARRVE------QLSDALLQQEAETMAEQGYRPKPYGHPK 494
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 52.0 bits (123), Expect = 1e-06
Identities = 63/285 (22%), Positives = 119/285 (41%), Gaps = 31/285 (10%)
Query: 62 EQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINE 121
EQ+ K L+ +++ K M F +K + L + N + R +I E
Sbjct: 240 EQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNA--------QLSRRTQQIQE 291
Query: 122 MLSTNLPVSLAP-EKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLA 180
L + + A EKED ++ + + DV+ K+ I ++ L + L
Sbjct: 292 ELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLR 351
Query: 181 PEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEET 240
E ++ +K++ + S ARD RL + + QQ QEK + QEE+
Sbjct: 352 EEAKEMWEKREAEWARERS-------ARD---RLMSEVLTGRQQQIQEKIEQNRRAQEES 401
Query: 241 MKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAK 300
+K R + + L+E +++ E S+ +KS +K + + ++ ++ E
Sbjct: 402 LKHREQLIRNLEEVRELARREKEESEKLKSARKQELE-AQVAERRLQAWEADQQEE---- 456
Query: 301 HELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQK 345
E EE+ +++ QL ALL+ E + + ++ K H K
Sbjct: 457 -EEEEEARRVE------QLSDALLQQEAETMAEQGYRPKPYGHPK 494
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 51.6 bits (122), Expect = 1e-06
Identities = 79/395 (20%), Positives = 157/395 (39%), Gaps = 63/395 (15%)
Query: 53 LKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKE-LFEETN--ITEDVSAH 109
LK H +++ K +N +K + K M ++ E E +F+ T+ + + H
Sbjct: 116 LKEIEHNLSK---IMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNH 172
Query: 110 KENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITE-DVSAHKENIRGLDKIN 168
+ +R ++ L + N++K E+++E + H+E+IR D +
Sbjct: 173 QRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLI 232
Query: 169 EMLSTNLPVSLAPEKEDNEKK----QQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQ 224
+ L+T L + +E++ +++ E Q E A L+N EK+ L + Q
Sbjct: 233 QSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKT---ANQLMNDFAEKETLKQKQ 289
Query: 225 QSQ-------------------EKAKNRL-NVQEETMKIRNNMEQLLQEAEHWSKQHTEL 264
+ K +N L NV+ E ++ + +++L+ + K EL
Sbjct: 290 IDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAEREL 349
Query: 265 SKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALL 324
SK K+ ETL + Q + + +L++++++L+H T + M L
Sbjct: 350 SKAEKNSN------VETLKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLT 403
Query: 325 ENECQILQQRVEILKELH--------------HQKQGTLQEKPIQINYKQDKKNQKPSEA 370
+++ +++ +K H Q + L K +IN +D+ + E
Sbjct: 404 KDKAD-KDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL 462
Query: 371 KKVEMYKQNKQAMKGTFWKKDRSCRS-----LDVC 400
E QNK + +K+ S DVC
Sbjct: 463 ASSE---QNKNHINNELKRKEEQLSSYEDKLFDVC 494
Score = 42.0 bits (97), Expect = 0.001
Identities = 68/342 (19%), Positives = 153/342 (44%), Gaps = 37/342 (10%)
Query: 53 LKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFE-ETNITEDVSAHKE 111
LK+ ++ +Q + +L + ++ + + + K+ E + +D +
Sbjct: 663 LKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQ 722
Query: 112 NIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEML 171
+++ NE+ S L +S ++ ++Q + L T + S ++E + E +
Sbjct: 723 HLKSTT--NELKSEKLQISTNLQRRQQLEEQTVELSTEVQ---SLYRE----IKDAKEQV 773
Query: 172 STNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEK-----KVLNETQQS 226
S P+ EK EK++ + N +NT+ A+D +N ++EK + + +
Sbjct: 774 S---PLETTLEKFQQEKEELI-----NKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENY 825
Query: 227 QEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNG 286
+ K+ Q+ET N + L E E ++ E +L++ +QK L +N
Sbjct: 826 IQDGKDDYKKQKETE--LNKVIAQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDN- 882
Query: 287 VGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQ 346
+ NE E+EE+ K+ + +Q++ +++E Q L++ ++ +K H+
Sbjct: 883 --LTLRKRNE--ELKEVEEERKQHLKEMGQMQVLQ--MKSEHQKLEENIDNIKRNHNLAL 936
Query: 347 GTLQ--EKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGT 386
G + E+ I I++K++ + + +A+ E Y++ M+ T
Sbjct: 937 GRQKGYEEEI-IHFKKELREPQFRDAE--EKYREMMIVMRTT 975
Score = 29.6 bits (65), Expect = 5.5
Identities = 34/149 (22%), Positives = 67/149 (44%), Gaps = 23/149 (15%)
Query: 211 VNRLEEKKVLNETQ-----QSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELS 265
+ LE + + +TQ + Q + K +E+ +IR+ + +EA Q T
Sbjct: 47 IKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITS--KEA-----QLTSSK 99
Query: 266 KLIKSYQKSQKDISETLGN--NGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAAL 323
+++KSY+ + L + + + +NE+ A L+ + K++ D L+
Sbjct: 100 EIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKA---LDSRKKQMEKDNSELE----- 151
Query: 324 LENECQILQQRVEILKELHHQKQGTLQEK 352
E ++ Q E L +L+H Q T++EK
Sbjct: 152 -EKMEKVFQGTDEQLNDLYHNHQRTVREK 179
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.123 0.330
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,031,349
Number of Sequences: 37866
Number of extensions: 677770
Number of successful extensions: 5405
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 770
Number of HSP's that attempted gapping in prelim test: 3658
Number of HSP's gapped (non-prelim): 1944
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.