Search of human proteins with 228008291

Search of human proteins with 228008291

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 1 [Homo sapiens]
         (623 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ...  1289   0.0  
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ...  1198   0.0  
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ...  1133   0.0  
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ...  1129   0.0  
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [...  1056   0.0  
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1...  1051   0.0  
gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting ...  1038   0.0  
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ...   938   0.0  
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4...   922   0.0  
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3...   916   0.0  
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]    353   3e-97
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]    340   2e-93
gi|20357575 apobec-1 complementation factor isoform 2 [Homo sapi...   334   1e-91
gi|20357572 apobec-1 complementation factor isoform 1 [Homo sapi...   334   1e-91
gi|21450675 RNA binding motif protein 46 [Homo sapiens]               333   3e-91
gi|20357578 apobec-1 complementation factor isoform 3 [Homo sapi...   318   1e-86
gi|34740339 dead end homolog 1 [Homo sapiens]                         134   2e-31
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...   103   6e-22
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...    94   5e-19
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...    94   5e-19
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...    94   5e-19
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]      89   1e-17
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]      86   8e-17
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s...    86   1e-16
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b...    84   5e-16
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa...    82   1e-15
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...    80   4e-15
gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Hom...    78   3e-14
gi|58761496 heterogeneous nuclear ribonucleoprotein A1-like [Hom...    78   3e-14
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s...    77   4e-14

>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 1 [Homo sapiens]
          Length = 623

 Score = 1289 bits (3335), Expect = 0.0
 Identities = 623/623 (100%), Positives = 623/623 (100%)

Query: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
           MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60

Query: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
           AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120

Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
           EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180

Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
           LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240

Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
           ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300

Query: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
           QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ
Sbjct: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360

Query: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
           FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR
Sbjct: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420

Query: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480
           QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG
Sbjct: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480

Query: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540
           YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG
Sbjct: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540

Query: 541 GAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDH 600
           GAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDH
Sbjct: 541 GAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDH 600

Query: 601 SGNYGYKSENQEFYQDTFGQQWK 623
           SGNYGYKSENQEFYQDTFGQQWK
Sbjct: 601 SGNYGYKSENQEFYQDTFGQQWK 623


>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 4 [Homo sapiens]
          Length = 588

 Score = 1198 bits (3100), Expect = 0.0
 Identities = 588/623 (94%), Positives = 588/623 (94%), Gaps = 35/623 (5%)

Query: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
           MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60

Query: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
           AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120

Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
           EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180

Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
           LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240

Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
           ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300

Query: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
           Q                                   VKVLFVRNLANTVTEEILEKAFSQ
Sbjct: 301 Q-----------------------------------VKVLFVRNLANTVTEEILEKAFSQ 325

Query: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
           FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR
Sbjct: 326 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 385

Query: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480
           QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG
Sbjct: 386 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 445

Query: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540
           YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG
Sbjct: 446 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 505

Query: 541 GAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDH 600
           GAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDH
Sbjct: 506 GAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDH 565

Query: 601 SGNYGYKSENQEFYQDTFGQQWK 623
           SGNYGYKSENQEFYQDTFGQQWK
Sbjct: 566 SGNYGYKSENQEFYQDTFGQQWK 588


>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 5 [Homo sapiens]
          Length = 561

 Score = 1133 bits (2931), Expect = 0.0
 Identities = 551/556 (99%), Positives = 552/556 (99%)

Query: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
           MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60

Query: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
           AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120

Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
           EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180

Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
           LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240

Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
           ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300

Query: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
           QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ
Sbjct: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360

Query: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
           FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR
Sbjct: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420

Query: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480
           QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG
Sbjct: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480

Query: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540
           YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG
Sbjct: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540

Query: 541 GAQQQRGRGVRGARGG 556
           GAQQQRGRG +G   G
Sbjct: 541 GAQQQRGRGGKGVEAG 556


>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 6 [Homo sapiens]
          Length = 562

 Score = 1129 bits (2920), Expect = 0.0
 Identities = 549/549 (100%), Positives = 549/549 (100%)

Query: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
           MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60

Query: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
           AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120

Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
           EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180

Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
           LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240

Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
           ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300

Query: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
           QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ
Sbjct: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360

Query: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
           FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR
Sbjct: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420

Query: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480
           QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG
Sbjct: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480

Query: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540
           YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG
Sbjct: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540

Query: 541 GAQQQRGRG 549
           GAQQQRGRG
Sbjct: 541 GAQQQRGRG 549


>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
           [Homo sapiens]
          Length = 633

 Score = 1056 bits (2732), Expect = 0.0
 Identities = 520/631 (82%), Positives = 574/631 (90%), Gaps = 15/631 (2%)

Query: 6   VNGNGT-----EEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
           VNGN       EEPMDT+S V H+E+++TL++AGLPQKVAE+LDEI+  GLVA+ DLDER
Sbjct: 5   VNGNAVQLKEEEEPMDTSS-VTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDER 63

Query: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
           AI+AL+EFNE+GAL+VLQQFK+SDLSHVQNKSAFLCGVMKTYRQREKQG+KV +S+KGPD
Sbjct: 64  AIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPD 123

Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
           EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSG QP +GTE+FVGKIPRDL+EDELVP
Sbjct: 124 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 183

Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
           LFEKAGPIWDLRLMMDPL+G NRGYAF+TFC KEAAQEAVKL +++EIR GKH+GVCISV
Sbjct: 184 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 243

Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
           ANNRLFVGSIPK+KTKE ILEEFSKVTEGL DVILYHQPDDKKKNRGFCFLEYEDHK+AA
Sbjct: 244 ANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAA 303

Query: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
           QARRRLMSGKVKVWGNV TVEWADP+E+PDPEVMAKVKVLFVRNLA TVTEEILEK+FS+
Sbjct: 304 QARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSE 363

Query: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
           FGKLERVKKLKDYAF+HF++R  AVKAM+EMNGK++EGE IEIV AKPPD+KRKER+A R
Sbjct: 364 FGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAAR 423

Query: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGR-GGRGGYGYPPDYYGYEDYY-DYYGYDYHNYR 478
           QA+++  Y+DYYY+ PP MPPP RGRGR GGRGGYGYPPDYYGYEDYY DYYGYDYH+YR
Sbjct: 424 QASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYR 483

Query: 479 GGYEDPYYGYED-FQVGARGRGGRGARGA-APSRGRGAAPPRGRAGYSQRGGP-GSARGV 535
           GGYEDPYYGY+D + V  RG GGRG RGA  P RGRGA PPRGRAGYSQRG P G  RG 
Sbjct: 484 GGYEDPYYGYDDGYAVRGRG-GGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGS 542

Query: 536 RGARGG-AQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNN-QNWGSQPIAQQ 593
           RG RGG AQQQRGRG RG+RG RGGNVGGKRKADGYNQPDSKRRQTNN QNWGSQPIAQQ
Sbjct: 543 RGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQ 602

Query: 594 PL-QGGDHSGNYGYKSENQEFYQDTFGQQWK 623
           PL QGGD+SGNYGY ++NQEFYQDT+GQQWK
Sbjct: 603 PLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK 633


>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
           [Homo sapiens]
          Length = 636

 Score = 1051 bits (2718), Expect = 0.0
 Identities = 520/634 (82%), Positives = 574/634 (90%), Gaps = 18/634 (2%)

Query: 6   VNGNGT-----EEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
           VNGN       EEPMDT+S V H+E+++TL++AGLPQKVAE+LDEI+  GLVA+ DLDER
Sbjct: 5   VNGNAVQLKEEEEPMDTSS-VTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDER 63

Query: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
           AI+AL+EFNE+GAL+VLQQFK+SDLSHVQNKSAFLCGVMKTYRQREKQG+KV +S+KGPD
Sbjct: 64  AIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPD 123

Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
           EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSG QP +GTE+FVGKIPRDL+EDELVP
Sbjct: 124 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 183

Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
           LFEKAGPIWDLRLMMDPL+G NRGYAF+TFC KEAAQEAVKL +++EIR GKH+GVCISV
Sbjct: 184 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 243

Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKV---TEGLTDVILYHQPDDKKKNRGFCFLEYEDHK 297
           ANNRLFVGSIPK+KTKE ILEEFSKV   TEGL DVILYHQPDDKKKNRGFCFLEYEDHK
Sbjct: 244 ANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 303

Query: 298 TAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKA 357
           +AAQARRRLMSGKVKVWGNV TVEWADP+E+PDPEVMAKVKVLFVRNLA TVTEEILEK+
Sbjct: 304 SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS 363

Query: 358 FSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 417
           FS+FGKLERVKKLKDYAF+HF++R  AVKAM+EMNGK++EGE IEIV AKPPD+KRKER+
Sbjct: 364 FSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQ 423

Query: 418 AQRQAAKNQMYDDYYYYGPPHMPPPTRGRGR-GGRGGYGYPPDYYGYEDYY-DYYGYDYH 475
           A RQA+++  Y+DYYY+ PP MPPP RGRGR GGRGGYGYPPDYYGYEDYY DYYGYDYH
Sbjct: 424 AARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH 483

Query: 476 NYRGGYEDPYYGYED-FQVGARGRGGRGARGA-APSRGRGAAPPRGRAGYSQRGGP-GSA 532
           +YRGGYEDPYYGY+D + V  RG GGRG RGA  P RGRGA PPRGRAGYSQRG P G  
Sbjct: 484 DYRGGYEDPYYGYDDGYAVRGRG-GGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPP 542

Query: 533 RGVRGARGG-AQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNN-QNWGSQPI 590
           RG RG RGG AQQQRGRG RG+RG RGGNVGGKRKADGYNQPDSKRRQTNN QNWGSQPI
Sbjct: 543 RGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPI 602

Query: 591 AQQPL-QGGDHSGNYGYKSENQEFYQDTFGQQWK 623
           AQQPL QGGD+SGNYGY ++NQEFYQDT+GQQWK
Sbjct: 603 AQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK 636


>gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 3 [Homo sapiens]
          Length = 527

 Score = 1038 bits (2685), Expect = 0.0
 Identities = 514/549 (93%), Positives = 514/549 (93%), Gaps = 35/549 (6%)

Query: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60
           MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER
Sbjct: 1   MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDER 60

Query: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120
           AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD
Sbjct: 61  AIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPD 120

Query: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180
           EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP
Sbjct: 121 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVP 180

Query: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240
           LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV
Sbjct: 181 LFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISV 240

Query: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
           ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA
Sbjct: 241 ANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300

Query: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
           Q                                   VKVLFVRNLANTVTEEILEKAFSQ
Sbjct: 301 Q-----------------------------------VKVLFVRNLANTVTEEILEKAFSQ 325

Query: 361 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 420
           FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR
Sbjct: 326 FGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQR 385

Query: 421 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 480
           QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG
Sbjct: 386 QAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGG 445

Query: 481 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 540
           YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG
Sbjct: 446 YEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARG 505

Query: 541 GAQQQRGRG 549
           GAQQQRGRG
Sbjct: 506 GAQQQRGRG 514


>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 2 [Homo sapiens]
          Length = 464

 Score =  938 bits (2424), Expect = 0.0
 Identities = 451/451 (100%), Positives = 451/451 (100%)

Query: 99  MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP 158
           MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP
Sbjct: 1   MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP 60

Query: 159 SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 218
           SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE
Sbjct: 61  SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 120

Query: 219 AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQ 278
           AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQ
Sbjct: 121 AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQ 180

Query: 279 PDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVK 338
           PDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVK
Sbjct: 181 PDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVK 240

Query: 339 VLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEG 398
           VLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEG
Sbjct: 241 VLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEG 300

Query: 399 ENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPP 458
           ENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPP
Sbjct: 301 ENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPP 360

Query: 459 DYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPR 518
           DYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPR
Sbjct: 361 DYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPR 420

Query: 519 GRAGYSQRGGPGSARGVRGARGGAQQQRGRG 549
           GRAGYSQRGGPGSARGVRGARGGAQQQRGRG
Sbjct: 421 GRAGYSQRGGPGSARGVRGARGGAQQQRGRG 451


>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
           [Homo sapiens]
          Length = 532

 Score =  922 bits (2382), Expect = 0.0
 Identities = 449/533 (84%), Positives = 488/533 (91%), Gaps = 9/533 (1%)

Query: 99  MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP 158
           MKTYRQREKQG+KV +S+KGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSG QP
Sbjct: 1   MKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQP 60

Query: 159 SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 218
            +GTE+FVGKIPRDL+EDELVPLFEKAGPIWDLRLMMDPL+G NRGYAF+TFC KEAAQE
Sbjct: 61  GIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQE 120

Query: 219 AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQ 278
           AVKL +++EIR GKH+GVCISVANNRLFVGSIPK+KTKE ILEEFSKVTEGL DVILYHQ
Sbjct: 121 AVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQ 180

Query: 279 PDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVK 338
           PDDKKKNRGFCFLEYEDHK+AAQARRRLMSGKVKVWGNV TVEWADP+E+PDPEVMAKVK
Sbjct: 181 PDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVK 240

Query: 339 VLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEG 398
           VLFVRNLA TVTEEILEK+FS+FGKLERVKKLKDYAF+HF++R  AVKAM+EMNGK++EG
Sbjct: 241 VLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEG 300

Query: 399 ENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGR-GGRGGYGYP 457
           E IEIV AKPPD+KRKER+A RQA+++  Y+DYYY+ PP MPPP RGRGR GGRGGYGYP
Sbjct: 301 EEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYP 360

Query: 458 PDYYGYEDYY-DYYGYDYHNYRGGYEDPYYGYED-FQVGARGRGGRGARGA-APSRGRGA 514
           PDYYGYEDYY DYYGYDYH+YRGGYEDPYYGY+D + V  RG GGRG RGA  P RGRGA
Sbjct: 361 PDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRG-GGRGGRGAPPPPRGRGA 419

Query: 515 APPRGRAGYSQRGGP-GSARGVRGARGG-AQQQRGRGVRGARGGRGGNVGGKRKADGYNQ 572
            PPRGRAGYSQRG P G  RG RG RGG AQQQRGRG RG+RG RGGNVGGKRKADGYNQ
Sbjct: 420 PPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADGYNQ 479

Query: 573 PDSKRRQTNN-QNWGSQPIAQQPL-QGGDHSGNYGYKSENQEFYQDTFGQQWK 623
           PDSKRRQTNN QNWGSQPIAQQPL QGGD+SGNYGY ++NQEFYQDT+GQQWK
Sbjct: 480 PDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK 532


>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
           [Homo sapiens]
          Length = 535

 Score =  916 bits (2368), Expect = 0.0
 Identities = 449/536 (83%), Positives = 488/536 (91%), Gaps = 12/536 (2%)

Query: 99  MKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQP 158
           MKTYRQREKQG+KV +S+KGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSG QP
Sbjct: 1   MKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQP 60

Query: 159 SVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQE 218
            +GTE+FVGKIPRDL+EDELVPLFEKAGPIWDLRLMMDPL+G NRGYAF+TFC KEAAQE
Sbjct: 61  GIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQE 120

Query: 219 AVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVT---EGLTDVIL 275
           AVKL +++EIR GKH+GVCISVANNRLFVGSIPK+KTKE ILEEFSKVT   EGL DVIL
Sbjct: 121 AVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVIL 180

Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
           YHQPDDKKKNRGFCFLEYEDHK+AAQARRRLMSGKVKVWGNV TVEWADP+E+PDPEVMA
Sbjct: 181 YHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMA 240

Query: 336 KVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKD 395
           KVKVLFVRNLA TVTEEILEK+FS+FGKLERVKKLKDYAF+HF++R  AVKAM+EMNGK+
Sbjct: 241 KVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKE 300

Query: 396 LEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGR-GGRGGY 454
           +EGE IEIV AKPPD+KRKER+A RQA+++  Y+DYYY+ PP MPPP RGRGR GGRGGY
Sbjct: 301 IEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGY 360

Query: 455 GYPPDYYGYEDYY-DYYGYDYHNYRGGYEDPYYGYED-FQVGARGRGGRGARGA-APSRG 511
           GYPPDYYGYEDYY DYYGYDYH+YRGGYEDPYYGY+D + V  RG GGRG RGA  P RG
Sbjct: 361 GYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRG-GGRGGRGAPPPPRG 419

Query: 512 RGAAPPRGRAGYSQRGGP-GSARGVRGARGG-AQQQRGRGVRGARGGRGGNVGGKRKADG 569
           RGA PPRGRAGYSQRG P G  RG RG RGG AQQQRGRG RG+RG RGGNVGGKRKADG
Sbjct: 420 RGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADG 479

Query: 570 YNQPDSKRRQTNN-QNWGSQPIAQQPL-QGGDHSGNYGYKSENQEFYQDTFGQQWK 623
           YNQPDSKRRQTNN QNWGSQPIAQQPL QGGD+SGNYGY ++NQEFYQDT+GQQWK
Sbjct: 480 YNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK 535


>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
          Length = 593

 Score =  353 bits (905), Expect = 3e-97
 Identities = 210/445 (47%), Positives = 274/445 (61%), Gaps = 51/445 (11%)

Query: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
           KV +   G P+EA + AL+ERTGY++    GQRKYGGPPP   + G  P  G E+FVGKI
Sbjct: 21  KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78

Query: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
           PRD++EDELVP+FE  G I++LRLMMD   G NRGYAFV +C K  A+ AV+  NN+EIR
Sbjct: 79  PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137

Query: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
            G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y    DK KNRGF 
Sbjct: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197

Query: 290 FLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTV 349
           F+EYE H+ AA ARR+LM G++++WG+   V+WA+P  D D +VM  VK+L+VRNL    
Sbjct: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257

Query: 350 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
           TE+ ++K+F QF  G +ERVKK++DYAF+HF  R+ AV AM  +NG +LEG  +E+  AK
Sbjct: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317

Query: 408 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 466
           P D   KE+ ++ Q A                      RG G       P   Y  + Y 
Sbjct: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353

Query: 467 YDYYGYDYHNYRGGYEDPYYGYEDFQVGA-RGRGGRGARGAAPSRGRGAAPPRGRAGYSQ 525
             YYGY Y+   G   D +      + G+ RGRG    RGAA +R  G   PRG    S 
Sbjct: 354 LAYYGYPYNALIGPNRDYF-----VKAGSIRGRG----RGAAGNRAPG---PRG----SY 397

Query: 526 RGGPGSARGV--RGARG-GAQQQRG 547
            GG  + RG+  R   G G QQ++G
Sbjct: 398 LGGYSAGRGIYSRYHEGKGKQQEKG 422


>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
          Length = 524

 Score =  340 bits (873), Expect = 2e-93
 Identities = 187/390 (47%), Positives = 246/390 (63%), Gaps = 31/390 (7%)

Query: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
           KV +   G P+EA + AL+ERTGY++    GQRKYGGPPP   + G  P  G E+FVGKI
Sbjct: 21  KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78

Query: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
           PRD++EDELVP+FE  G I++LRLMMD   G NRGYAFV +C K  A+ AV+  NN+EIR
Sbjct: 79  PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137

Query: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
            G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y    DK KNRGF 
Sbjct: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197

Query: 290 FLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTV 349
           F+EYE H+ AA ARR+LM G++++WG+   V+WA+P  D D +VM  VK+L+VRNL    
Sbjct: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257

Query: 350 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
           TE+ ++K+F QF  G +ERVKK++DYAF+HF  R+ AV AM  +NG +LEG  +E+  AK
Sbjct: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317

Query: 408 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 466
           P D   KE+ ++ Q A                      RG G       P   Y  + Y 
Sbjct: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353

Query: 467 YDYYGYDYHNYRGGYEDPYYGYEDFQVGAR 496
             YYGY Y+   G   D +       +GA+
Sbjct: 354 LAYYGYPYNALIGPNRDYFVKVAIPAIGAQ 383


>gi|20357575 apobec-1 complementation factor isoform 2 [Homo
           sapiens]
          Length = 594

 Score =  334 bits (857), Expect = 1e-91
 Identities = 185/417 (44%), Positives = 253/417 (60%), Gaps = 24/417 (5%)

Query: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
           K G  ++ + K   EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G EIF+
Sbjct: 6   KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60

Query: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
           GK+PRDLFEDEL+PL EK G I+++R+MMD   G NRGYAFVTF  K  A+ A+K  NN+
Sbjct: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119

Query: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
           EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E  KVTEG+ DVI+Y    DK KNR
Sbjct: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179

Query: 287 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 346
           GF F+EYE H+ AA ARR+L+ G++++WG+   V+WA+P  + D + M+ VK+L+VRNL 
Sbjct: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239

Query: 347 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 404
            + +EE++EK F+    G +ERVKK++DYAF+HF  R+ AV+AM+ +NGK L+G  IE+ 
Sbjct: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299

Query: 405 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 464
            AKP D+    R  +    +  M    Y Y    +  PT          Y   P +Y  +
Sbjct: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351

Query: 465 DYYDYYGYDYHNYRGGYEDPYY--------GYEDFQVGARGRGGRGARGAAPSRGRG 513
            Y       +   +G   +            Y +  VGA G  G G RG     G G
Sbjct: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLG 408


>gi|20357572 apobec-1 complementation factor isoform 1 [Homo
           sapiens]
          Length = 586

 Score =  334 bits (857), Expect = 1e-91
 Identities = 183/409 (44%), Positives = 250/409 (61%), Gaps = 16/409 (3%)

Query: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
           K G  ++ + K   EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G EIF+
Sbjct: 6   KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60

Query: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
           GK+PRDLFEDEL+PL EK G I+++R+MMD   G NRGYAFVTF  K  A+ A+K  NN+
Sbjct: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119

Query: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
           EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E  KVTEG+ DVI+Y    DK KNR
Sbjct: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179

Query: 287 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 346
           GF F+EYE H+ AA ARR+L+ G++++WG+   V+WA+P  + D + M+ VK+L+VRNL 
Sbjct: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239

Query: 347 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 404
            + +EE++EK F+    G +ERVKK++DYAF+HF  R+ AV+AM+ +NGK L+G  IE+ 
Sbjct: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299

Query: 405 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 464
            AKP D+    R  +    +  M    Y Y    +  PT          Y   P +Y  +
Sbjct: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351

Query: 465 DYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRG 513
            Y       +   +G   +          GA G  G G RG     G G
Sbjct: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLG 400


>gi|21450675 RNA binding motif protein 46 [Homo sapiens]
          Length = 533

 Score =  333 bits (854), Expect = 3e-91
 Identities = 164/300 (54%), Positives = 222/300 (74%), Gaps = 5/300 (1%)

Query: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179
           +EA + AL+E+TGY +    GQRK+GGPPP   + G  P  G E+FVGKIPRD++EDELV
Sbjct: 21  NEAALLALMEKTGYNMVQENGQRKFGGPPPG--WEGPPPPRGCEVFVGKIPRDMYEDELV 78

Query: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239
           P+FE+AG I++ RLMM+  +G NRGYAFV + TKE AQ A+++ NN+EIR GK IGVC+S
Sbjct: 79  PVFERAGKIYEFRLMME-FSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137

Query: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299
           + N RLF+G+IPK K KE+IL+E  KVTEG+ DVI+Y    DK KNRGF F+EYE H+ A
Sbjct: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197

Query: 300 AQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFS 359
           A ARR+L+ G  ++WG+   V+WADP ++ D E M +VKVL+VRNL  + TEE ++  F+
Sbjct: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257

Query: 360 QF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERK 417
           +F  G +ERVKKL+DYAF+HF  R+ AV AM  MNGK ++G +IE+  AKP +++   R+
Sbjct: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQ 317


>gi|20357578 apobec-1 complementation factor isoform 3 [Homo
           sapiens]
          Length = 594

 Score =  318 bits (814), Expect = 1e-86
 Identities = 172/381 (45%), Positives = 232/381 (60%), Gaps = 13/381 (3%)

Query: 135 LDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 194
           L+   GQRKYGGPPP   +    P  G EIF+GK+PRDLFEDEL+PL EK G I+++R+M
Sbjct: 39  LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96

Query: 195 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSK 254
           MD   G NRGYAFVTF  K  A+ A+K  NN+EIR+G+ +GVC SV N RLFVG IPK+K
Sbjct: 97  MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155

Query: 255 TKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVW 314
            +E+IL E  KVTEG+ DVI+Y    DK KNRGF F+EYE H+ AA ARR+L+ G++++W
Sbjct: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215

Query: 315 GNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQF--GKLERVKKLKD 372
           G+   V+WA+P  + D + M+ VK+L+VRNL  + +EE++EK F+    G +ERVKK++D
Sbjct: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275

Query: 373 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYY 432
           YAF+HF  R+ AV+AM+ +NGK L+G  IE+  AKP D+    R  +    +  M    Y
Sbjct: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335

Query: 433 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQ 492
            Y    +  PT          Y   P +Y  + Y       +   +G   +         
Sbjct: 336 TYSLGQVYDPTT--------TYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSV 387

Query: 493 VGARGRGGRGARGAAPSRGRG 513
            GA G  G G RG     G G
Sbjct: 388 RGAAGVRGLGGRGYLAYTGLG 408


>gi|34740339 dead end homolog 1 [Homo sapiens]
          Length = 353

 Score =  134 bits (338), Expect = 2e-31
 Identities = 70/206 (33%), Positives = 114/206 (55%), Gaps = 5/206 (2%)

Query: 120 DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELV 179
           ++A ++A +  TG  L    GQRKYGGPPP  V  G  P  G+E+F+G++P+D++E +L+
Sbjct: 18  NKAALEAWVRETGIRLVQVNGQRKYGGPPPGWV--GSPPPAGSEVFIGRLPQDVYEHQLI 75

Query: 180 PLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCIS 239
           PLF++ G +++ RLMM   +GLNRG+A+  + ++  AQ A+   +NH +R    + VC S
Sbjct: 76  PLFQRVGRLYEFRLMM-TFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRS 134

Query: 240 VANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTA 299
                L V  +P + T+  +L     +  GL +  L   P           L++  H+ A
Sbjct: 135 TEKCELSVDGLPPNLTRSALLLALQPLGPGLQEARLLPSPGPAPGQ--IALLKFSSHRAA 192

Query: 300 AQARRRLMSGKVKVWGNVGTVEWADP 325
           A A++ L+ G+  + G    VEW  P
Sbjct: 193 AMAKKALVEGQSHLCGEQVAVEWLKP 218


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score =  103 bits (256), Expect = 6e-22
 Identities = 77/284 (27%), Positives = 141/284 (49%), Gaps = 33/284 (11%)

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           ++VG +  D+ ED L   F   GP+  +R+  D +T  + GYA+V F     AQ+A+   
Sbjct: 12  LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71

Query: 224 NNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
           N  +I  GK I +  S  +          +F+ ++ KS   + + E FS   + L+  ++
Sbjct: 72  N-FDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130

Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
                D + ++G+ F+ +++   A +A    M+GK+     V    + +  +D + E+ +
Sbjct: 131 ----SDDQGSKGYAFVHFQNQSAADRAIEE-MNGKLLKGCKVFVGRFKNR-KDREAELRS 184

Query: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVK-------KLKDYAFIHFDERDGAV 385
           K      ++++N    + +E L+  FS++GK   VK       K K + F+ FD  + A 
Sbjct: 185 KASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAK 244

Query: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYD 429
           KA+EEMNG+D+ G+ I +         R ++K +RQA   QM++
Sbjct: 245 KAVEEMNGRDINGQLIFV--------GRAQKKVERQAELKQMFE 280



 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 73/284 (25%), Positives = 121/284 (42%), Gaps = 55/284 (19%)

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           +F+  + + +    L   F   G I   ++M D     ++GYAFV F  + AA  A++  
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG--SKGYAFVHFQNQSAADRAIEEM 157

Query: 224 NNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILE----EFSKV----------TEG 269
           N      GK +  C      ++FVG     K +E  L     EF+ V           E 
Sbjct: 158 N------GKLLKGC------KVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDER 205

Query: 270 LTDVILYH--------QPDDKKKNRGFCFLEYEDHKTAAQARRRL----MSGKV------ 311
           L DV   +          D   K++GF F+ ++ H+ A +A   +    ++G++      
Sbjct: 206 LKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265

Query: 312 --KVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKK 369
             KV       +  + ++         VK L+++NL +T+ +E L   FS FG + RVK 
Sbjct: 266 QKKVERQAELKQMFEQLKRERIRGCQGVK-LYIKNLDDTIDDEKLRNEFSSFGSISRVKV 324

Query: 370 L------KDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
           +      K +  I F   + A KAM EMNG+ L  + + I  A+
Sbjct: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 74/286 (25%), Positives = 142/286 (49%), Gaps = 25/286 (8%)

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           ++VG +  D+ E  L   F  AGP+  +R+  D +T  + GYA+V F     A+ A+   
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 224 NNHEIRSGKHIGVCISVANNRL--------FVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
           N  ++  GK I +  S  +  L        F+ ++ KS   + + + FS     L+  ++
Sbjct: 73  N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
                D+  ++G+ F+ +E  + A +A  + M+G +     V    +    ++ + E+ A
Sbjct: 132 C----DENGSKGYAFVHFETQEAADKAIEK-MNGMLLNDRKVFVGRFKSR-KEREAELGA 185

Query: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAV 385
           K K    ++++N    V +E L++ FSQFGK   VK ++D       + F+ +++ + A 
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245

Query: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDY 431
           KA+EEMNGK++ G+ I +  A+   +++ E K + +  K +    Y
Sbjct: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRY 291



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 78/310 (25%), Positives = 144/310 (46%), Gaps = 49/310 (15%)

Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
           G P   ++S + PS+       +F+  + + +    L   F   G I   +++ D     
Sbjct: 79  GKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136

Query: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247
           ++GYAFV F T+EAA +A++     L N+ ++  G+          +G       N +++
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTN-VYI 195

Query: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLM 307
            +  +    E + E FS+  + L+  ++    D   K++GF F+ YE H+ A +A    M
Sbjct: 196 KNFGEEVDDESLKELFSQFGKTLSVKVMR---DPNGKSKGFGFVSYEKHEDANKAVEE-M 251

Query: 308 SGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVL-------------FVRNLANTVTEEIL 354
           +GK ++ G +  V  A    +   E+  K + L             +++NL +T+ +E L
Sbjct: 252 NGK-EISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKL 310

Query: 355 EKAFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKP 408
            K FS FG +   K      + K + F+ F   + A KA+ EMNG+ +  + + +  A  
Sbjct: 311 RKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA-- 368

Query: 409 PDQKRKERKA 418
             Q+++ERKA
Sbjct: 369 --QRKEERKA 376


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 74/286 (25%), Positives = 142/286 (49%), Gaps = 25/286 (8%)

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           ++VG +  D+ E  L   F  AGP+  +R+  D +T  + GYA+V F     A+ A+   
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 224 NNHEIRSGKHIGVCISVANNRL--------FVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
           N  ++  GK I +  S  +  L        F+ ++ KS   + + + FS     L+  ++
Sbjct: 73  N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
                D+  ++G+ F+ +E  + A +A  + M+G +     V    +    ++ + E+ A
Sbjct: 132 C----DENGSKGYAFVHFETQEAADKAIEK-MNGMLLNDRKVFVGRFKSR-KEREAELGA 185

Query: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAV 385
           K K    ++++N    V +E L++ FSQFGK   VK ++D       + F+ +++ + A 
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245

Query: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDY 431
           KA+EEMNGK++ G+ I +  A+   +++ E K + +  K +    Y
Sbjct: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRY 291



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 78/310 (25%), Positives = 144/310 (46%), Gaps = 49/310 (15%)

Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
           G P   ++S + PS+       +F+  + + +    L   F   G I   +++ D     
Sbjct: 79  GKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136

Query: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247
           ++GYAFV F T+EAA +A++     L N+ ++  G+          +G       N +++
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTN-VYI 195

Query: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLM 307
            +  +    E + E FS+  + L+  ++    D   K++GF F+ YE H+ A +A    M
Sbjct: 196 KNFGEEVDDESLKELFSQFGKTLSVKVMR---DPNGKSKGFGFVSYEKHEDANKAVEE-M 251

Query: 308 SGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVL-------------FVRNLANTVTEEIL 354
           +GK ++ G +  V  A    +   E+  K + L             +++NL +T+ +E L
Sbjct: 252 NGK-EISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKL 310

Query: 355 EKAFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKP 408
            K FS FG +   K      + K + F+ F   + A KA+ EMNG+ +  + + +  A  
Sbjct: 311 RKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA-- 368

Query: 409 PDQKRKERKA 418
             Q+++ERKA
Sbjct: 369 --QRKEERKA 376


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 74/286 (25%), Positives = 142/286 (49%), Gaps = 25/286 (8%)

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           ++VG +  D+ E  L   F  AGP+  +R+  D +T  + GYA+V F     A+ A+   
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 224 NNHEIRSGKHIGVCISVANNRL--------FVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
           N  ++  GK I +  S  +  L        F+ ++ KS   + + + FS     L+  ++
Sbjct: 73  N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
                D+  ++G+ F+ +E  + A +A  + M+G +     V    +    ++ + E+ A
Sbjct: 132 C----DENGSKGYAFVHFETQEAADKAIEK-MNGMLLNDRKVFVGRFKSR-KEREAELGA 185

Query: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAV 385
           K K    ++++N    V +E L++ FSQFGK   VK ++D       + F+ +++ + A 
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245

Query: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDY 431
           KA+EEMNGK++ G+ I +  A+   +++ E K + +  K +    Y
Sbjct: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRY 291



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 78/310 (25%), Positives = 144/310 (46%), Gaps = 49/310 (15%)

Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
           G P   ++S + PS+       +F+  + + +    L   F   G I   +++ D     
Sbjct: 79  GKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136

Query: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247
           ++GYAFV F T+EAA +A++     L N+ ++  G+          +G       N +++
Sbjct: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTN-VYI 195

Query: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLM 307
            +  +    E + E FS+  + L+  ++    D   K++GF F+ YE H+ A +A    M
Sbjct: 196 KNFGEEVDDESLKELFSQFGKTLSVKVMR---DPNGKSKGFGFVSYEKHEDANKAVEE-M 251

Query: 308 SGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVL-------------FVRNLANTVTEEIL 354
           +GK ++ G +  V  A    +   E+  K + L             +++NL +T+ +E L
Sbjct: 252 NGK-EISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKL 310

Query: 355 EKAFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKP 408
            K FS FG +   K      + K + F+ F   + A KA+ EMNG+ +  + + +  A  
Sbjct: 311 RKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA-- 368

Query: 409 PDQKRKERKA 418
             Q+++ERKA
Sbjct: 369 --QRKEERKA 376


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 75/292 (25%), Positives = 142/292 (48%), Gaps = 30/292 (10%)

Query: 158 PSVGT-EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAA 216
           PS  T  ++VG +  D+ E  L   F  AGPI  +R+  D +T  +  YA+V F   + A
Sbjct: 6   PSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDA 65

Query: 217 QEAVKLYNNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTE 268
           + A+   N  ++  GK + +  S  +          +FV ++ KS   + + +  S    
Sbjct: 66  EHALDTMN-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS---- 120

Query: 269 GLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIED 328
              +++  +   D+  ++G+ F+ +E H+ A +A ++ M+G +     V   ++    ++
Sbjct: 121 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKK-MNGMLLNGRKVFVGQFKSR-KE 178

Query: 329 PDPEVMAKVKV---LFVRNLANTVTEEILEKAFSQFGKLERVK-------KLKDYAFIHF 378
            + E+ A+ K    ++++N    + +E L+  F +FG    VK       K K + F+ F
Sbjct: 179 REAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSF 238

Query: 379 DERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDD 430
           +  + A KA++EMNGK+L G+ I +  A    QK+ ER+ + +    QM  D
Sbjct: 239 ERHEDAQKAVDEMNGKELNGKQIYVGRA----QKKVERQTELKRTFEQMKQD 286



 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 86/326 (26%), Positives = 132/326 (40%), Gaps = 65/326 (19%)

Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
           G P   ++S + PS+       IFV  + + +    L       G I    ++ D     
Sbjct: 79  GKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NG 136

Query: 202 NRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQIL- 260
           ++GY FV F T EAA+ A+K  N   +   K            +FVG     K +E  L 
Sbjct: 137 SKGYGFVHFETHEAAERAIKKMNGMLLNGRK------------VFVGQFKSRKEREAELG 184

Query: 261 ---EEFSKV----------TEGLTDVILYHQP--------DDKKKNRGFCFLEYEDHKTA 299
              +EF  V           E L D+     P        D+  K++GF F+ +E H+ A
Sbjct: 185 ARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDA 244

Query: 300 AQARRRL----MSGKVKVWGNVGT-----VEWADPIEDPDPEVMAKVKV--LFVRNLANT 348
            +A   +    ++GK    G          E     E    + + + +V  L+V+NL + 
Sbjct: 245 QKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDG 304

Query: 349 VTEEILEKAFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIE 402
           + +E L KAFS FG +   K      + K + F+ F   + A KA+ EMNG+        
Sbjct: 305 IDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGR-------- 356

Query: 403 IVFAKPPDQKRKERKAQRQAAKNQMY 428
           IV  KP      +RK +RQA     Y
Sbjct: 357 IVATKPLYVALAQRKEERQAYLTNEY 382


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score = 86.3 bits (212), Expect = 8e-17
 Identities = 73/285 (25%), Positives = 137/285 (48%), Gaps = 29/285 (10%)

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           ++VG +  D+ E  L   F  AGPI  +R+  D +T  + GYA+V F     A+ A+   
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 224 NNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
           N  ++  GK + +  S  +          +F+ ++ KS   + + + FS     L+  ++
Sbjct: 73  N-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
                D+  ++G+ F+ +E  + A +A  + M+G +     V    +    ++ + E+ A
Sbjct: 132 C----DENGSKGYGFVHFETQEAAERAIEK-MNGMLLNDRKVFVGRFKSR-KEREAELGA 185

Query: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVK-------KLKDYAFIHFDERDGAV 385
           + K    ++++N    + +E L+  F +FG    VK       K K + F+ F+  + A 
Sbjct: 186 RAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQ 245

Query: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDD 430
           KA++EMNGK+L G+ I +  A    QK+ ER+ + +    QM  D
Sbjct: 246 KAVDEMNGKELNGKQIYVGRA----QKKVERQTELKRKFEQMKQD 286



 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 80/320 (25%), Positives = 140/320 (43%), Gaps = 53/320 (16%)

Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
           G P   ++S + PS+       IF+  + + +    L   F   G I   +++ D     
Sbjct: 79  GKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136

Query: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247
           ++GY FV F T+EAA+ A++     L N+ ++  G+          +G       N +++
Sbjct: 137 SKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTN-VYI 195

Query: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLM 307
            +  +    E++ + F K    L+  ++    D+  K++GF F+ +E H+ A +A    M
Sbjct: 196 KNFGEDMDDERLKDLFGKFGPALSVKVM---TDESGKSKGFGFVSFERHEDAQKAVDE-M 251

Query: 308 SGKVKVWGNVGTVEWADPIEDPDPEVMAKVKV-------------LFVRNLANTVTEEIL 354
           +GK ++ G    V  A    +   E+  K +              L+V+NL + + +E L
Sbjct: 252 NGK-ELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERL 310

Query: 355 EKAFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKP 408
            K FS FG +   K      + K + F+ F   + A KA+ EMNG+        IV  KP
Sbjct: 311 RKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGR--------IVATKP 362

Query: 409 PDQKRKERKAQRQAAKNQMY 428
                 +RK +RQA     Y
Sbjct: 363 LYVALAQRKEERQAHLTNQY 382


>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
           sapiens]
          Length = 614

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 77/285 (27%), Positives = 133/285 (46%), Gaps = 29/285 (10%)

Query: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
           ++VG +  D+ E  L   F  AGPI  +R+  D  T  + GYA++ F     A+ A+   
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72

Query: 224 NNHEIRSGKHIGVCISVAN--------NRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
            N E+  G+ I +  S  +          +F+ ++  S   + + + FS       +++ 
Sbjct: 73  -NFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFST----FGNILS 127

Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQA---RRRLMSGKVKVWGNVGTVEWADPIEDPDPE 332
                D+  +RGF F+ +E H+ A QA      ++    KV+  VG  +     E     
Sbjct: 128 CKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVF--VGHFKSRREREAELGA 185

Query: 333 VMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAV 385
              +   ++V+NL   V E+ L+  FSQFGK+  VK ++D       + F++F++ + A 
Sbjct: 186 RALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQ 245

Query: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDD 430
           KA+  MNGK++ G  +    A    QKR ER+ + +    QM  D
Sbjct: 246 KAVVHMNGKEVSGRLLYAGRA----QKRVERQNELKRRFEQMKQD 286



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 72/310 (23%), Positives = 135/310 (43%), Gaps = 49/310 (15%)

Query: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
           G P   ++S + P +       IF+  +   +    L   F   G I   ++  D     
Sbjct: 79  GQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG-- 136

Query: 202 NRGYAFVTFCTKEAAQEAVKLYNNHEIRSGK--------------HIGVCISVANNRLFV 247
           +RG+ FV F T EAAQ+A+   N   +   K               +G       N ++V
Sbjct: 137 SRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTN-IYV 195

Query: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLM 307
            ++P    ++ + + FS+  + L+  ++    D+   +R F F+ +E H+ A +A    M
Sbjct: 196 KNLPVDVDEQGLQDLFSQFGKMLSVKVMR---DNSGHSRCFGFVNFEKHEEAQKAVVH-M 251

Query: 308 SGKVKVWGNVGTVEWADPIEDPDPEVMAKVKV-------------LFVRNLANTVTEEIL 354
           +GK +V G +     A    +   E+  + +              L+V+NL +++ ++ L
Sbjct: 252 NGK-EVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKL 310

Query: 355 EKAFSQFGKLERVKKL------KDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKP 408
            K FS +G +   K +      K + F+ F   + A KA+ EMNG+ +  + + +  A  
Sbjct: 311 RKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALA-- 368

Query: 409 PDQKRKERKA 418
             Q+++ERKA
Sbjct: 369 --QRKEERKA 376


>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
           [Homo sapiens]
          Length = 372

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 101/381 (26%), Positives = 144/381 (37%), Gaps = 48/381 (12%)

Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQAR 303
           +LF+G +    T E +   F +    LTD ++   P+ K+ +RGF F+ Y    T  +  
Sbjct: 15  KLFIGGLSFETTDESLRSHFEQWGT-LTDCVVMRDPNTKR-SRGFGFVTYA---TVEEVD 69

Query: 304 RRLMSGKVKVWGNVGTVEWADPIEDPD-PEVMAKVKVLFVRNLANTVTEEILEKAFSQFG 362
             + +   KV G V   + A   ED   P     VK +FV  +     E  L   F Q+G
Sbjct: 70  AAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYG 129

Query: 363 KLERVKKLKD--------YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRK 414
           K+E ++ + D        +AF+ FD+ D   K + +     + G N E+  A    +   
Sbjct: 130 KIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKY-HTVNGHNCEVRKALSKQEMAS 188

Query: 415 ERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDY 474
              +QR  + +  +               RG G GG   +G   ++ G        G+  
Sbjct: 189 ASSSQRGRSGSGNFGG------------GRGGGFGGNDNFGRGGNFSGRG------GFGG 230

Query: 475 HNYRGGYEDPYYGYEDF-QVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSAR 533
               GGY     GY  F   G  G GG G  G   SRG G+    G  GY   G  GS  
Sbjct: 231 SRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGG--SRGYGS----GGQGY---GNQGSGY 281

Query: 534 GVRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQ 593
           G  G+        G G  G  G   G  G       YN   S        N+G +  +  
Sbjct: 282 GGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGR--SSG 339

Query: 594 PLQGGDHSGNYGYKSENQEFY 614
           P  GG   G Y  K  NQ  Y
Sbjct: 340 PYGGG---GQYFAKPRNQGGY 357



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 26/160 (16%)

Query: 154 SGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTK 213
           S ++P    ++F+G +  +  ++ L   FE+ G + D  +M DP T  +RG+ FVT+ T 
Sbjct: 6   SPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATV 65

Query: 214 EAAQEAVKLYNNHEI-----------------RSGKHIGVCISVANNRLFVGSIPKSKTK 256
           E    A+     H++                 R G H+ V       ++FVG I K  T+
Sbjct: 66  EEVDAAMNA-RPHKVDGRVVEPKRAVSREDSQRPGAHLTV------KKIFVGGI-KEDTE 117

Query: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDH 296
           E  L ++ +   G  +VI         K RGF F+ ++DH
Sbjct: 118 EHHLRDYFE-QYGKIEVIEIMTDRGSGKKRGFAFVTFDDH 156



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 73/306 (23%), Positives = 117/306 (38%), Gaps = 47/306 (15%)

Query: 331 PEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLE--------RVKKLKDYAFIHF---D 379
           P+   +++ LF+  L+   T+E L   F Q+G L           K+ + + F+ +   +
Sbjct: 7   PKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66

Query: 380 ERDGAVKAM-EEMNGKDLEGEN-IEIVFAKPPDQKRKERKA-----QRQAAKNQMYDDYY 432
           E D A+ A   +++G+ +E +  +    ++ P      +K      +    ++ + D + 
Sbjct: 67  EVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFE 126

Query: 433 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYD------YYGYDYHNYRGGYEDPYY 486
            YG   +      RG G + G+ +    +   D  D      Y+  + HN          
Sbjct: 127 QYGKIEVIEIMTDRGSGKKRGFAFVT--FDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQ 184

Query: 487 GYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAG-YSQRGGPGSARGVRGARGGAQQQ 545
                    RGR G G  G     G G     GR G +S RGG G +RG  G  G     
Sbjct: 185 EMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGY 244

Query: 546 RGRGVRGARGGRG-GNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNY 604
            G G  G  GG G G  GG R   GY         +  Q +G+        QG  + G+ 
Sbjct: 245 NGFGNDGGYGGGGPGYSGGSR---GYG--------SGGQGYGN--------QGSGYGGSG 285

Query: 605 GYKSEN 610
            Y S N
Sbjct: 286 SYDSYN 291



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 23/58 (39%), Positives = 32/58 (55%)

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAV 220
           +IFVG I  D  E  L   FE+ G I  + +M D  +G  RG+AFVTF   ++  + V
Sbjct: 106 KIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIV 163


>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 485

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 12/173 (6%)

Query: 145 GGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRG 204
           G  PP     G +     ++FVG+IPR L E +L PLFE+ G I++L ++ DP TG+++G
Sbjct: 28  GPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGMHKG 87

Query: 205 YAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANN--------RLFVGSIPKSKTK 256
            AF+T+C +++A +A    +  +   G    + +  A++        +LFVG + K +++
Sbjct: 88  CAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSE 147

Query: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSG 309
           E +L  F      + +  +   PD   K  G  F+++  H T AQA    + G
Sbjct: 148 EDVLRLFQPFGV-IDECTVLRGPDGSSK--GCAFVKFSSH-TEAQAAIHALHG 196



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/82 (26%), Positives = 41/82 (50%)

Query: 147 PPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYA 206
           PPP      ++   G  +F+  +P++  + EL  +F   G I   ++ MD  T  ++ + 
Sbjct: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444

Query: 207 FVTFCTKEAAQEAVKLYNNHEI 228
           FV+F    +AQ A++  N  +I
Sbjct: 445 FVSFDNPASAQAAIQAMNGFQI 466



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 8/125 (6%)

Query: 298 TAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKA 357
           T ++ARR+           VG+     P   PD         LFV  +   + E+ L+  
Sbjct: 5   TESEARRQQQQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPL 64

Query: 358 FSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP 409
           F QFG++  +  LKD         AF+ +  RD A+KA   ++ +         +  KP 
Sbjct: 65  FEQFGRIYELTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPA 124

Query: 410 DQKRK 414
           D + +
Sbjct: 125 DSESR 129



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 8/79 (10%)

Query: 340 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 391
           LF+ +L     +  L + F  FG +   K   D        + F+ FD    A  A++ M
Sbjct: 402 LFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNPASAQAAIQAM 461

Query: 392 NGKDLEGENIEIVFAKPPD 410
           NG  +  + +++   +P D
Sbjct: 462 NGFQIGMKRLKVQLKRPKD 480


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 103/379 (27%), Positives = 150/379 (39%), Gaps = 81/379 (21%)

Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEY---EDHKTAA 300
           +LF+G +    T + + E F K    LTD ++   P  K+ +RGF F+ Y   E+   A 
Sbjct: 36  KLFIGGLSFETTDDSLREHFEKWGT-LTDCVVMRDPQTKR-SRGFGFVTYSCVEEVDAAM 93

Query: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPD---PEVMAKVKVLFVRNLANTVTEEILEKA 357
            AR   + G+V        VE    +   D   P     VK +FV  +     E  L   
Sbjct: 94  CARPHKVDGRV--------VEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDY 145

Query: 358 FSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPP 409
           F ++GK+E ++ ++D        +AF+ FD+ D   K + +     + G N E+      
Sbjct: 146 FEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKY-HTINGHNCEV------ 198

Query: 410 DQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDY 469
             K+   K + Q+A +Q                   RGRGG  G     ++ G    +  
Sbjct: 199 --KKALSKQEMQSAGSQ-------------------RGRGGGSG-----NFMGRGGNFGG 232

Query: 470 YGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGP 529
            G ++   RGG      GY        G GG G+RG+    G G     G  G +  GGP
Sbjct: 233 GGGNFG--RGGNFGGRGGY--------GGGGGGSRGSY-GGGDGGYNGFGGDGGNYGGGP 281

Query: 530 G-SARGVRGARGGAQQQRGRGVRGARG----GRGGNVGGKRKADGYNQPDSKRRQTNNQ- 583
           G S+RG  G  G     +G G  G  G      GGN GG     G N  D        Q 
Sbjct: 282 GYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQS 341

Query: 584 NWGSQPIAQQPLQGGDHSG 602
           N+G       P++GG   G
Sbjct: 342 NYG-------PMKGGSFGG 353



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 34/180 (18%)

Query: 145 GGPPPDSV----------YSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 194
           G P PDS           +  ++P    ++F+G +  +  +D L   FEK G + D  +M
Sbjct: 8   GRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVM 67

Query: 195 MDPLTGLNRGYAFVTFCTKEAAQEAV----------------KLYNNHEIRSGKHIGVCI 238
            DP T  +RG+ FVT+   E    A+                 +     ++ G H+ V  
Sbjct: 68  RDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTV-- 125

Query: 239 SVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKT 298
                ++FVG I +   +  + + F K   G  + I   +     K RGF F+ ++DH T
Sbjct: 126 ----KKIFVGGIKEDTEEYNLRDYFEKY--GKIETIEVMEDRQSGKKRGFAFVTFDDHDT 179



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 29/71 (40%), Positives = 37/71 (52%), Gaps = 1/71 (1%)

Query: 150 DSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVT 209
           DSV  G   +V  +IFVG I  D  E  L   FEK G I  + +M D  +G  RG+AFVT
Sbjct: 115 DSVKPGAHLTV-KKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVT 173

Query: 210 FCTKEAAQEAV 220
           F   +   + V
Sbjct: 174 FDDHDTVDKIV 184



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 66/309 (21%), Positives = 117/309 (37%), Gaps = 42/309 (13%)

Query: 327 EDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKL--------ERVKKLKDYAFIHF 378
           E  DP+   +++ LF+  L+   T++ L + F ++G L         + K+ + + F+ +
Sbjct: 24  EGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTY 83

Query: 379 ---DERDGAVKAM-EEMNGKDLEGEN-IEIVFAKPPDQKRKERK-----AQRQAAKNQMY 428
              +E D A+ A   +++G+ +E +  +    +  P      +K      +    +  + 
Sbjct: 84  SCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLR 143

Query: 429 DDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGY 488
           D +  YG          R  G + G+ +   +  ++         YH   G   +     
Sbjct: 144 DYFEKYGKIETIEVMEDRQSGKKRGFAF-VTFDDHDTVDKIVVQKYHTINGHNCEVKKAL 202

Query: 489 EDFQV----GARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQ 544
              ++      RGRGG    G+    GRG     G   + + G  G   G  G  GG++ 
Sbjct: 203 SKQEMQSAGSQRGRGG----GSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRG 258

Query: 545 QRGRGVRGAR--GGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSG 602
             G G  G    GG GGN GG     GY+             +G+        QGG + G
Sbjct: 259 SYGGGDGGYNGFGGDGGNYGG---GPGYSSRGG--YGGGGPGYGN--------QGGGYGG 305

Query: 603 NYGYKSENQ 611
             GY   N+
Sbjct: 306 GGGYDGYNE 314


>gi|58761498 heterogeneous nuclear ribonucleoprotein A1-like [Homo
           sapiens]
          Length = 320

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 85/310 (27%), Positives = 127/310 (40%), Gaps = 26/310 (8%)

Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQAR 303
           +LF+G +    T E +   F +    LTD ++   P+ K+ +RGF F+ Y    T  +  
Sbjct: 15  KLFIGGLSFETTDESLRSHFEQWGT-LTDCVVMRDPNTKR-SRGFGFVTYA---TVEEVD 69

Query: 304 RRLMSGKVKVWGNVGTVEWADPIEDPD-PEVMAKVKVLFVRNLANTVTEEILEKAFSQFG 362
             + +   KV G V   + A   ED   P     VK +FV  +     E  L   F Q+G
Sbjct: 70  AAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYG 129

Query: 363 KLERVK--------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRK 414
           K+E ++        K + +AF+ FD+ D   K + +     ++G N E+  A P  +   
Sbjct: 130 KIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQ-KYHTVKGHNCEVRKALPKQEMAS 188

Query: 415 ERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYP---PDYYGYEDYYDYYG 471
              +QR    +  +      G        RG    GRGG+G       Y G  D Y+ +G
Sbjct: 189 ASSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSGDGYNGFG 248

Query: 472 YDYHNYRGG--YED-PYYGYEDFQVGARGRGGRGARGAAPSRGRGA--APPRGRAGY--- 523
            D  N+ GG  Y D   Y  +    G    G  G R + P  G G   A P+ + GY   
Sbjct: 249 NDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPQNQGGYGVS 308

Query: 524 SQRGGPGSAR 533
           S     GS R
Sbjct: 309 SSSSSYGSGR 318



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 26/160 (16%)

Query: 154 SGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTK 213
           S ++P    ++F+G +  +  ++ L   FE+ G + D  +M DP T  +RG+ FVT+ T 
Sbjct: 6   SPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATV 65

Query: 214 EAAQEAVKLYNNHEI-----------------RSGKHIGVCISVANNRLFVGSIPKSKTK 256
           E    A+     H++                 R G H+ V       ++FVG I K  T+
Sbjct: 66  EEVDAAMNT-TPHKVDGRVVEPKRAVSREDSQRPGAHLTV------KKIFVGGI-KEDTE 117

Query: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDH 296
           E  L ++ +   G  +VI         K RGF F+ ++DH
Sbjct: 118 EHHLRDYFE-QYGKIEVIEIMTDRGSGKKRGFAFVTFDDH 156



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 35/309 (11%)

Query: 331 PEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLE--------RVKKLKDYAFIHF---D 379
           P+   +++ LF+  L+   T+E L   F Q+G L           K+ + + F+ +   +
Sbjct: 7   PKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66

Query: 380 ERDGAVKAM-EEMNGKDLEGEN-IEIVFAKPPDQKRKERKA-----QRQAAKNQMYDDYY 432
           E D A+     +++G+ +E +  +    ++ P      +K      +    ++ + D + 
Sbjct: 67  EVDAAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFE 126

Query: 433 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYD------YYGYDYHNYRGGYEDPYY 486
            YG   +      RG G + G+ +    +   D  D      Y+    HN       P  
Sbjct: 127 QYGKIEVIEIMTDRGSGKKRGFAFVT--FDDHDSVDKIVIQKYHTVKGHNCEVRKALPKQ 184

Query: 487 GYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAG-YSQRGGPGSARGVRGARGGAQQQ 545
                    RGR G G  G     G G     GR G +S RGG G + G  G  G     
Sbjct: 185 EMASASSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSGDGY 244

Query: 546 RGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYG 605
            G G  G+  G GG+         YN   S        N+G +  +  P  GG   G Y 
Sbjct: 245 NGFGNDGSNFGGGGSY---NDFGNYNNQSSNFGPMKGGNFGGR--SSGPYGGG---GQYF 296

Query: 606 YKSENQEFY 614
            K +NQ  Y
Sbjct: 297 AKPQNQGGY 305



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 1/98 (1%)

Query: 123 KIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLF 182
           ++ A +  T + +D    + K      DS   G   +V  +IFVG I  D  E  L   F
Sbjct: 67  EVDAAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTV-KKIFVGGIKEDTEEHHLRDYF 125

Query: 183 EKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAV 220
           E+ G I  + +M D  +G  RG+AFVTF   ++  + V
Sbjct: 126 EQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIV 163


>gi|58761496 heterogeneous nuclear ribonucleoprotein A1-like [Homo
           sapiens]
          Length = 320

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 85/310 (27%), Positives = 127/310 (40%), Gaps = 26/310 (8%)

Query: 244 RLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQAR 303
           +LF+G +    T E +   F +    LTD ++   P+ K+ +RGF F+ Y    T  +  
Sbjct: 15  KLFIGGLSFETTDESLRSHFEQWGT-LTDCVVMRDPNTKR-SRGFGFVTYA---TVEEVD 69

Query: 304 RRLMSGKVKVWGNVGTVEWADPIEDPD-PEVMAKVKVLFVRNLANTVTEEILEKAFSQFG 362
             + +   KV G V   + A   ED   P     VK +FV  +     E  L   F Q+G
Sbjct: 70  AAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYG 129

Query: 363 KLERVK--------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRK 414
           K+E ++        K + +AF+ FD+ D   K + +     ++G N E+  A P  +   
Sbjct: 130 KIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQ-KYHTVKGHNCEVRKALPKQEMAS 188

Query: 415 ERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYP---PDYYGYEDYYDYYG 471
              +QR    +  +      G        RG    GRGG+G       Y G  D Y+ +G
Sbjct: 189 ASSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSGDGYNGFG 248

Query: 472 YDYHNYRGG--YED-PYYGYEDFQVGARGRGGRGARGAAPSRGRGA--APPRGRAGY--- 523
            D  N+ GG  Y D   Y  +    G    G  G R + P  G G   A P+ + GY   
Sbjct: 249 NDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPQNQGGYGVS 308

Query: 524 SQRGGPGSAR 533
           S     GS R
Sbjct: 309 SSSSSYGSGR 318



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 44/160 (27%), Positives = 73/160 (45%), Gaps = 26/160 (16%)

Query: 154 SGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTK 213
           S ++P    ++F+G +  +  ++ L   FE+ G + D  +M DP T  +RG+ FVT+ T 
Sbjct: 6   SPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATV 65

Query: 214 EAAQEAVKLYNNHEI-----------------RSGKHIGVCISVANNRLFVGSIPKSKTK 256
           E    A+     H++                 R G H+ V       ++FVG I K  T+
Sbjct: 66  EEVDAAMNT-TPHKVDGRVVEPKRAVSREDSQRPGAHLTV------KKIFVGGI-KEDTE 117

Query: 257 EQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDH 296
           E  L ++ +   G  +VI         K RGF F+ ++DH
Sbjct: 118 EHHLRDYFE-QYGKIEVIEIMTDRGSGKKRGFAFVTFDDH 156



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 35/309 (11%)

Query: 331 PEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLE--------RVKKLKDYAFIHF---D 379
           P+   +++ LF+  L+   T+E L   F Q+G L           K+ + + F+ +   +
Sbjct: 7   PKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66

Query: 380 ERDGAVKAM-EEMNGKDLEGEN-IEIVFAKPPDQKRKERKA-----QRQAAKNQMYDDYY 432
           E D A+     +++G+ +E +  +    ++ P      +K      +    ++ + D + 
Sbjct: 67  EVDAAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFE 126

Query: 433 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYD------YYGYDYHNYRGGYEDPYY 486
            YG   +      RG G + G+ +    +   D  D      Y+    HN       P  
Sbjct: 127 QYGKIEVIEIMTDRGSGKKRGFAFVT--FDDHDSVDKIVIQKYHTVKGHNCEVRKALPKQ 184

Query: 487 GYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAG-YSQRGGPGSARGVRGARGGAQQQ 545
                    RGR G G  G     G G     GR G +S RGG G + G  G  G     
Sbjct: 185 EMASASSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGSGDGY 244

Query: 546 RGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYG 605
            G G  G+  G GG+         YN   S        N+G +  +  P  GG   G Y 
Sbjct: 245 NGFGNDGSNFGGGGSY---NDFGNYNNQSSNFGPMKGGNFGGR--SSGPYGGG---GQYF 296

Query: 606 YKSENQEFY 614
            K +NQ  Y
Sbjct: 297 AKPQNQGGY 305



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 1/98 (1%)

Query: 123 KIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLF 182
           ++ A +  T + +D    + K      DS   G   +V  +IFVG I  D  E  L   F
Sbjct: 67  EVDAAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTV-KKIFVGGIKEDTEEHHLRDYF 125

Query: 183 EKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAV 220
           E+ G I  + +M D  +G  RG+AFVTF   ++  + V
Sbjct: 126 EQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIV 163


>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
           sapiens]
          Length = 448

 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 43/147 (29%), Positives = 82/147 (55%), Gaps = 10/147 (6%)

Query: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
           ++F+G+IPR+L E +L PLFE+ G I++L ++ D  TG+++G AF+T+C +E+A +A   
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 223 YNNHEIRSGKHIGVCISVANN-------RLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
            +  +   G +  + +  A++       +LFVG + K ++++ +   F +    + +  +
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLF-EAFGNIEECTI 173

Query: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQA 302
              PD   K  G  F++Y  H  A  A
Sbjct: 174 LRGPDGNSK--GCAFVKYSSHAEAQAA 198



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 46/198 (23%), Positives = 87/198 (43%), Gaps = 22/198 (11%)

Query: 244 RLFVGSIPKS---KTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
           +LF+G IP++   K  + + EEF K+ E     +   +      ++G  FL Y + ++A 
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYE-----LTVLKDRFTGMHKGCAFLTYCERESAL 109

Query: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
           +A+  L   K     N         ++  D E   + + LFV  L    +E+ + + F  
Sbjct: 110 KAQSALHEQKTLPGMNRPI-----QVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEA 164

Query: 361 FGKLERVKKL-------KDYAFIHFDERDGAVKAMEEMNG-KDLEGENIEIVFA-KPPDQ 411
           FG +E    L       K  AF+ +     A  A+  ++G + + G +  +V      D+
Sbjct: 165 FGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDK 224

Query: 412 KRKERKAQRQAAKNQMYD 429
           +R  R+ Q+ A +  M++
Sbjct: 225 ERTMRRMQQMAGQMGMFN 242



 Score = 36.6 bits (83), Expect = 0.071
 Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 20/117 (17%)

Query: 307 MSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLER 366
           M+G     GN  T+    P++D D      +K LF+  +   + E+ L+  F +FGK+  
Sbjct: 33  MNGLSHSPGNPSTI----PMKDHDA-----IK-LFIGQIPRNLDEKDLKPLFEEFGKIYE 82

Query: 367 VKKLKD--------YAFIHFDERDGAVKAMEEMN-GKDLEGENIEIVFAKPPDQKRK 414
           +  LKD         AF+ + ER+ A+KA   ++  K L G N  I   KP D + +
Sbjct: 83  LTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQ-VKPADSESR 138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,075,068
Number of Sequences: 37866
Number of extensions: 1553802
Number of successful extensions: 13832
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 397
Number of HSP's successfully gapped in prelim test: 448
Number of HSP's that attempted gapping in prelim test: 6365
Number of HSP's gapped (non-prelim): 4256
length of query: 623
length of database: 18,247,518
effective HSP length: 108
effective length of query: 515
effective length of database: 14,157,990
effective search space: 7291364850
effective search space used: 7291364850
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.