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Search of human proteins with 22748617
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22748617 defensin, beta 105A precursor [Homo sapiens]
(78 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22748617 defensin, beta 105A precursor [Homo sapiens] 170 3e-43
gi|103485141 defensin, beta 105B precursor [Homo sapiens] 170 3e-43
gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens] 40 4e-04
gi|239748864 PREDICTED: defensin, beta 133 [Homo sapiens] 40 4e-04
gi|239742893 PREDICTED: beta-defensin 133 [Homo sapiens] 40 4e-04
gi|22748611 defensin, beta 106A precursor [Homo sapiens] 35 0.013
gi|82734219 beta-defensin 114 [Homo sapiens] 35 0.013
gi|103485143 defensin, beta 106B precursor [Homo sapiens] 35 0.013
gi|103485139 defensin, beta 104A precursor [Homo sapiens] 33 0.038
gi|103485137 defensin, beta 104B precursor [Homo sapiens] 33 0.038
gi|83582798 beta-defensin 115 [Homo sapiens] 33 0.064
gi|82734214 beta-defensin 111 [Homo sapiens] 33 0.064
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens] 32 0.14
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens] 32 0.14
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens] 32 0.14
gi|50344744 beta-defensin 108B [Homo sapiens] 32 0.14
gi|18250304 beta defensin 129 precursor [Homo sapiens] 30 0.32
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens] 29 0.71
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens] 28 1.2
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens] 28 1.2
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens] 28 1.2
gi|116517226 beta-defensin 135 [Homo sapiens] 28 1.2
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens] 28 1.2
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens] 28 2.1
gi|239749357 PREDICTED: hypothetical protein XP_002347009 [Homo ... 27 2.7
gi|103485147 defensin, beta 107B precursor [Homo sapiens] 27 3.5
gi|103485145 defensin, beta 107A precursor [Homo sapiens] 27 3.5
gi|239755437 PREDICTED: hypothetical protein [Homo sapiens] 27 4.6
gi|239749918 PREDICTED: hypothetical protein XP_002347213 [Homo ... 27 4.6
gi|239744221 PREDICTED: hypothetical protein XP_002343077 [Homo ... 27 4.6
>gi|22748617 defensin, beta 105A precursor [Homo sapiens]
Length = 78
Score = 170 bits (430), Expect = 3e-43
Identities = 78/78 (100%), Positives = 78/78 (100%)
Query: 1 MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLEN 60
MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLEN
Sbjct: 1 MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLEN 60
Query: 61 EKPDGNCRLNFLCCRQRI 78
EKPDGNCRLNFLCCRQRI
Sbjct: 61 EKPDGNCRLNFLCCRQRI 78
>gi|103485141 defensin, beta 105B precursor [Homo sapiens]
Length = 78
Score = 170 bits (430), Expect = 3e-43
Identities = 78/78 (100%), Positives = 78/78 (100%)
Query: 1 MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLEN 60
MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLEN
Sbjct: 1 MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLEN 60
Query: 61 EKPDGNCRLNFLCCRQRI 78
EKPDGNCRLNFLCCRQRI
Sbjct: 61 EKPDGNCRLNFLCCRQRI 78
>gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens]
Length = 61
Score = 40.0 bits (92), Expect = 4e-04
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 12/69 (17%)
Query: 6 KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65
K FLF +FF LV + + + + + SC + RGKCR EC + EKP G
Sbjct: 2 KIHVFLFVLFFFLVPIATRMKCAVKDTY-----------SCFIMRGKCRHECHDFEKPIG 50
Query: 66 NC-RLNFLC 73
C +LN C
Sbjct: 51 FCTKLNANC 59
>gi|239748864 PREDICTED: defensin, beta 133 [Homo sapiens]
Length = 61
Score = 40.0 bits (92), Expect = 4e-04
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 12/69 (17%)
Query: 6 KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65
K FLF +FF LV + + + + + SC + RGKCR EC + EKP G
Sbjct: 2 KIHVFLFVLFFFLVPIATRMKCAVKDTY-----------SCFIMRGKCRHECHDFEKPIG 50
Query: 66 NC-RLNFLC 73
C +LN C
Sbjct: 51 FCTKLNANC 59
>gi|239742893 PREDICTED: beta-defensin 133 [Homo sapiens]
Length = 61
Score = 40.0 bits (92), Expect = 4e-04
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 12/69 (17%)
Query: 6 KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65
K FLF +FF LV + + + + + SC + RGKCR EC + EKP G
Sbjct: 2 KIHVFLFVLFFFLVPIATRMKCAVKDTY-----------SCFIMRGKCRHECHDFEKPIG 50
Query: 66 NC-RLNFLC 73
C +LN C
Sbjct: 51 FCTKLNANC 59
>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
Length = 65
Score = 35.0 bits (79), Expect = 0.013
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 16/70 (22%)
Query: 6 KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65
+TF FLFA+ F L P+ E C +G C+ C +NE+
Sbjct: 2 RTFLFLFAVLFFLT----------------PAKNAFFDEKCNKLKGTCKNNCGKNEELIA 45
Query: 66 NCRLNFLCCR 75
C+ + CCR
Sbjct: 46 LCQKSLKCCR 55
>gi|82734219 beta-defensin 114 [Homo sapiens]
Length = 69
Score = 35.0 bits (79), Expect = 0.013
Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 14/74 (18%)
Query: 6 KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65
+ FY+L + ++ LP+ C + C G+C+++CLE+EK
Sbjct: 2 RIFYYLHFLCYVTFILPATCT-------------LVNADRCTKRYGRCKRDCLESEKQID 48
Query: 66 NCRL-NFLCCRQRI 78
C L +CC +++
Sbjct: 49 ICSLPRKICCTEKL 62
>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
Length = 65
Score = 35.0 bits (79), Expect = 0.013
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 16/70 (22%)
Query: 6 KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65
+TF FLFA+ F L P+ E C +G C+ C +NE+
Sbjct: 2 RTFLFLFAVLFFLT----------------PAKNAFFDEKCNKLKGTCKNNCGKNEELIA 45
Query: 66 NCRLNFLCCR 75
C+ + CCR
Sbjct: 46 LCQKSLKCCR 55
>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
Length = 72
Score = 33.5 bits (75), Expect = 0.038
Identities = 13/39 (33%), Positives = 19/39 (48%)
Query: 39 EFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQR 77
EF + C G +CRK+C E G C + CC ++
Sbjct: 23 EFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61
>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
Length = 72
Score = 33.5 bits (75), Expect = 0.038
Identities = 13/39 (33%), Positives = 19/39 (48%)
Query: 39 EFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQR 77
EF + C G +CRK+C E G C + CC ++
Sbjct: 23 EFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61
>gi|83582798 beta-defensin 115 [Homo sapiens]
Length = 88
Score = 32.7 bits (73), Expect = 0.064
Identities = 12/29 (41%), Positives = 15/29 (51%)
Query: 46 CKLGRGKCRKECLENEKPDGNCRLNFLCC 74
C G G+CRK C E E+ C +CC
Sbjct: 38 CYYGTGRCRKSCKEIERKKEKCGEKHICC 66
>gi|82734214 beta-defensin 111 [Homo sapiens]
Length = 67
Score = 32.7 bits (73), Expect = 0.064
Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 10/70 (14%)
Query: 10 FLFAMFFILVQLPSGCQAGLDFSQPFPS-GEFAVCESCKLGRGKCRKECLENEKPDGNC- 67
F F + F + LP+ + +P G + C++G G+C+ +C ENE C
Sbjct: 6 FFFILHFWVTILPA--------KKKYPEYGSLDLRRECRIGNGQCKNQCHENEIRIAYCI 57
Query: 68 RLNFLCCRQR 77
R CC Q+
Sbjct: 58 RPGTHCCLQQ 67
>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 31.6 bits (70), Expect = 0.14
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 16/65 (24%)
Query: 11 LFAMFFILVQLPSGCQAGLDFSQPFPS-GEFAVCESCKLGRGKCRKECLENEKPDGNCRL 69
LFA+FF + SQ P+ G+F E C+ G CR CLE E G C
Sbjct: 17 LFAIFFFM-------------SQVLPARGKFK--EICERPNGSCRDFCLETEIHVGRCLN 61
Query: 70 NFLCC 74
+ CC
Sbjct: 62 SRPCC 66
>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 31.6 bits (70), Expect = 0.14
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 16/65 (24%)
Query: 11 LFAMFFILVQLPSGCQAGLDFSQPFPS-GEFAVCESCKLGRGKCRKECLENEKPDGNCRL 69
LFA+FF + SQ P+ G+F E C+ G CR CLE E G C
Sbjct: 17 LFAIFFFM-------------SQVLPARGKFK--EICERPNGSCRDFCLETEIHVGRCLN 61
Query: 70 NFLCC 74
+ CC
Sbjct: 62 SRPCC 66
>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
Length = 73
Score = 31.6 bits (70), Expect = 0.14
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 16/65 (24%)
Query: 11 LFAMFFILVQLPSGCQAGLDFSQPFPS-GEFAVCESCKLGRGKCRKECLENEKPDGNCRL 69
LFA+FF + SQ P+ G+F E C+ G CR CLE E G C
Sbjct: 7 LFAIFFFM-------------SQVLPARGKFK--EICERPNGSCRDFCLETEIHVGRCLN 51
Query: 70 NFLCC 74
+ CC
Sbjct: 52 SRPCC 56
>gi|50344744 beta-defensin 108B [Homo sapiens]
Length = 73
Score = 31.6 bits (70), Expect = 0.14
Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 16/65 (24%)
Query: 11 LFAMFFILVQLPSGCQAGLDFSQPFPS-GEFAVCESCKLGRGKCRKECLENEKPDGNCRL 69
LFA+FF + SQ P+ G+F E C+ G CR CLE E G C
Sbjct: 7 LFAIFFFM-------------SQVLPARGKFK--EICERPNGSCRDFCLETEIHVGRCLN 51
Query: 70 NFLCC 74
+ CC
Sbjct: 52 SQPCC 56
>gi|18250304 beta defensin 129 precursor [Homo sapiens]
Length = 183
Score = 30.4 bits (67), Expect = 0.32
Identities = 12/40 (30%), Positives = 19/40 (47%)
Query: 39 EFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI 78
EF C +G G+CR C +EK C++ C ++
Sbjct: 20 EFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPKV 59
>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
Length = 84
Score = 29.3 bits (64), Expect = 0.71
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 1/48 (2%)
Query: 29 LDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQ 76
L +P SG+ + C G CR C +NE+P CR CC Q
Sbjct: 12 LAIEEPVISGKRHILR-CMGNSGICRASCKKNEQPYLYCRNCQSCCLQ 58
>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/31 (35%), Positives = 16/31 (51%)
Query: 44 ESCKLGRGKCRKECLENEKPDGNCRLNFLCC 74
+SC + +G CRK C E+ C+ CC
Sbjct: 16 KSCWIIKGHCRKNCKPGEQVKKPCKNGDYCC 46
>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/31 (35%), Positives = 16/31 (51%)
Query: 44 ESCKLGRGKCRKECLENEKPDGNCRLNFLCC 74
+SC + +G CRK C E+ C+ CC
Sbjct: 16 KSCWIIKGHCRKNCKPGEQVKKPCKNGDYCC 46
>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/31 (35%), Positives = 16/31 (51%)
Query: 44 ESCKLGRGKCRKECLENEKPDGNCRLNFLCC 74
+SC + +G CRK C E+ C+ CC
Sbjct: 16 KSCWIIKGHCRKNCKPGEQVKKPCKNGDYCC 46
>gi|116517226 beta-defensin 135 [Homo sapiens]
Length = 77
Score = 28.5 bits (62), Expect = 1.2
Identities = 13/30 (43%), Positives = 17/30 (56%)
Query: 45 SCKLGRGKCRKECLENEKPDGNCRLNFLCC 74
SC +G CR +CL+NE+ C LCC
Sbjct: 36 SCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
Length = 99
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/25 (44%), Positives = 13/25 (52%)
Query: 50 RGKCRKECLENEKPDGNCRLNFLCC 74
+G CRK C NE P+ C CC
Sbjct: 30 QGHCRKICRVNEVPEALCENGRYCC 54
>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
Length = 156
Score = 27.7 bits (60), Expect = 2.1
Identities = 13/37 (35%), Positives = 17/37 (45%)
Query: 38 GEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCC 74
G F + K G CR+ CL+ E+ CR CC
Sbjct: 20 GSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCC 56
>gi|239749357 PREDICTED: hypothetical protein XP_002347009 [Homo
sapiens]
Length = 111
Score = 27.3 bits (59), Expect = 2.7
Identities = 12/31 (38%), Positives = 15/31 (48%)
Query: 44 ESCKLGRGKCRKECLENEKPDGNCRLNFLCC 74
E C+ G C+ CLE E G C + CC
Sbjct: 64 EICERPNGSCQDFCLETEIHVGRCLNSRPCC 94
>gi|103485147 defensin, beta 107B precursor [Homo sapiens]
Length = 70
Score = 26.9 bits (58), Expect = 3.5
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 14/74 (18%)
Query: 6 KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65
K F F+ A +L Q+ QA + S K G C ECL E G
Sbjct: 6 KIFVFILAALILLAQI---FQARTAIHRALIS---------KRMEGHCEAECLTFEVKIG 53
Query: 66 NCRLNF--LCCRQR 77
CR CC+ R
Sbjct: 54 GCRAELAPFCCKNR 67
>gi|103485145 defensin, beta 107A precursor [Homo sapiens]
Length = 70
Score = 26.9 bits (58), Expect = 3.5
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 14/74 (18%)
Query: 6 KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65
K F F+ A +L Q+ QA + S K G C ECL E G
Sbjct: 6 KIFVFILAALILLAQI---FQARTAIHRALIS---------KRMEGHCEAECLTFEVKIG 53
Query: 66 NCRLNF--LCCRQR 77
CR CC+ R
Sbjct: 54 GCRAELAPFCCKNR 67
>gi|239755437 PREDICTED: hypothetical protein [Homo sapiens]
Length = 199
Score = 26.6 bits (57), Expect = 4.6
Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 15 FFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGN 66
FF+ V LP G +G DFS G F + G G C + + P G+
Sbjct: 138 FFVAVSLPGGGGSGADFSL---LGAFLGLVALLGGLGSCGRRSHSSPGPAGS 186
>gi|239749918 PREDICTED: hypothetical protein XP_002347213 [Homo
sapiens]
Length = 122
Score = 26.6 bits (57), Expect = 4.6
Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 15 FFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGN 66
FF+ V LP G +G DFS G F + G G C + + P G+
Sbjct: 61 FFVAVSLPGGGGSGADFSL---LGAFLGLVALLGGLGSCGRRSHSSPGPAGS 109
>gi|239744221 PREDICTED: hypothetical protein XP_002343077 [Homo
sapiens]
Length = 199
Score = 26.6 bits (57), Expect = 4.6
Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 15 FFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGN 66
FF+ V LP G +G DFS G F + G G C + + P G+
Sbjct: 138 FFVAVSLPGGGGSGADFSL---LGAFLGLVALLGGLGSCGRRSHSSPGPAGS 186
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.333 0.147 0.495
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,616,987
Number of Sequences: 37866
Number of extensions: 159198
Number of successful extensions: 361
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 328
Number of HSP's gapped (non-prelim): 37
length of query: 78
length of database: 18,247,518
effective HSP length: 50
effective length of query: 28
effective length of database: 16,354,218
effective search space: 457918104
effective search space used: 457918104
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.