BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|226693407 TBC1 domain family, member 3H [Homo sapiens] (549 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 1153 0.0 gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 1151 0.0 gi|183583563 TBC1 domain family, member 3D [Homo sapiens] 1149 0.0 gi|90577185 TBC1 domain family member 3C [Homo sapiens] 1148 0.0 gi|183583565 TBC1 domain family, member 3 [Homo sapiens] 1148 0.0 gi|183583567 TBC1 domain family, member 3E [Homo sapiens] 1148 0.0 gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 1145 0.0 gi|149999613 TBC1 domain family, member 3B [Homo sapiens] 1142 0.0 gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 844 0.0 gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ... 495 e-140 gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 244 1e-64 gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 244 1e-64 gi|148235002 TBC1 domain family, member 26 [Homo sapiens] 236 4e-62 gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo ... 186 5e-47 gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens] 181 1e-45 gi|239756750 PREDICTED: similar to TBC1 domain family, member 28... 169 6e-42 gi|151108489 TBC1 domain family, member 28 [Homo sapiens] 169 6e-42 gi|239751314 PREDICTED: hypothetical protein XP_002347802 [Homo ... 154 2e-37 gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 130 3e-30 gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 130 4e-30 gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo sapi... 130 4e-30 gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 107 3e-23 gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 105 8e-23 gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 105 1e-22 gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 88 2e-17 gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 86 1e-16 gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 86 1e-16 gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 85 1e-16 gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 85 1e-16 gi|7661586 TBC1 domain family, member 29 [Homo sapiens] 84 4e-16 >gi|226693407 TBC1 domain family, member 3H [Homo sapiens] Length = 549 Score = 1153 bits (2982), Expect = 0.0 Identities = 549/549 (100%), Positives = 549/549 (100%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 Query: 541 ESSQFPPGF 549 ESSQFPPGF Sbjct: 541 ESSQFPPGF 549 >gi|157502205 TBC1 domain family, member 3G [Homo sapiens] Length = 549 Score = 1151 bits (2978), Expect = 0.0 Identities = 548/549 (99%), Positives = 549/549 (100%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEVAGSWWAQEREDIIMKYEKGH+AGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 Query: 541 ESSQFPPGF 549 ESSQFPPGF Sbjct: 541 ESSQFPPGF 549 >gi|183583563 TBC1 domain family, member 3D [Homo sapiens] Length = 549 Score = 1149 bits (2973), Expect = 0.0 Identities = 546/549 (99%), Positives = 549/549 (100%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEVAGSWWAQEREDIIMKYEKGH+AGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKEKGKRSSEHIQRIDRD+SGTLRKH+FFRDRYGTKQRELLHILLAYEEY Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 Query: 541 ESSQFPPGF 549 ESSQFPPGF Sbjct: 541 ESSQFPPGF 549 >gi|90577185 TBC1 domain family member 3C [Homo sapiens] Length = 549 Score = 1148 bits (2970), Expect = 0.0 Identities = 547/549 (99%), Positives = 548/549 (99%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEVAGSWWAQEREDIIMKYEKGH+AGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVVATSQ KTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI Sbjct: 241 HVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 Query: 541 ESSQFPPGF 549 ESSQFPPGF Sbjct: 541 ESSQFPPGF 549 >gi|183583565 TBC1 domain family, member 3 [Homo sapiens] Length = 549 Score = 1148 bits (2969), Expect = 0.0 Identities = 545/549 (99%), Positives = 549/549 (100%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEVAGSWWAQEREDIIMKYEKGH+AGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKEKGKRSSEHIQRIDRD+SGTLRKH+FFRDRYGTKQRELLHILLAYEEY Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRK+GDLPPP Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 Query: 541 ESSQFPPGF 549 ESSQFPPGF Sbjct: 541 ESSQFPPGF 549 >gi|183583567 TBC1 domain family, member 3E [Homo sapiens] Length = 549 Score = 1148 bits (2969), Expect = 0.0 Identities = 545/549 (99%), Positives = 549/549 (100%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEVAGSWWAQEREDIIMKYEKGH+AGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKEKGKRSSEHIQRIDRD+SGTLRKH+FFRDRYGTKQRELLHILLAYEEY Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRK+GDLPPP Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 Query: 541 ESSQFPPGF 549 ESSQFPPGF Sbjct: 541 ESSQFPPGF 549 >gi|14149985 TBC1 domain family, member 3F [Homo sapiens] Length = 549 Score = 1145 bits (2961), Expect = 0.0 Identities = 543/549 (98%), Positives = 548/549 (99%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEVAGSWWAQEREDIIMKYEKGH+AGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLN EEM Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEM 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKEKGK+SSEHIQRIDRD+SGTLRKH+FFRDRYGTKQRELLHILLAYEEY Sbjct: 121 KLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEY 180 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE Sbjct: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI Sbjct: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRK+GDLPPP Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPP 360 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 Query: 541 ESSQFPPGF 549 ESSQFPPGF Sbjct: 541 ESSQFPPGF 549 >gi|149999613 TBC1 domain family, member 3B [Homo sapiens] Length = 549 Score = 1142 bits (2955), Expect = 0.0 Identities = 545/549 (99%), Positives = 546/549 (99%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEVAGSWWAQEREDIIMKYEKGH+AGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL Sbjct: 1 MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM Sbjct: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHIAALFLLY PEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE Sbjct: 181 NPEVGYCRDLSHIAALFLLYFPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVVATSQ KTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI Sbjct: 241 HVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP Sbjct: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA Sbjct: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV Sbjct: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 Query: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHL 540 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQ APTSGPCLCGLHL Sbjct: 481 RAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQYAPTSGPCLCGLHL 540 Query: 541 ESSQFPPGF 549 ESSQFPPGF Sbjct: 541 ESSQFPPGF 549 >gi|109638751 ubiquitin specific protease 6 [Homo sapiens] Length = 1406 Score = 844 bits (2180), Expect = 0.0 Identities = 406/500 (81%), Positives = 440/500 (88%), Gaps = 1/500 (0%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MD+VE A S AQER+DI+MKY+KGH+AGLPEDKGP+P N+++D GI+HETELPP+ Sbjct: 1 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPV-GINSSIDRFGILHETELPPV 59 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TAREAK+IRRE++R SKW++MLG+WE YK S KLIDR YKG+PMNIRGP+WSVLLNI+E+ Sbjct: 60 TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEY 180 KLKNPGRYQIMKE+GKRSSEHI ID D+ TLR H+FFRDRYG KQREL +ILLAY EY Sbjct: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179 Query: 181 NPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQE 240 NPEVGYCRDLSHI ALFLLYLPEEDAFWALVQLLASERHSL GFHSPNGGTVQGLQDQQE Sbjct: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQE 239 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 HVV SQPKTM HQDK+ LCGQC+ LGCL+R LIDGISLGLTLRLWDVYLVEGEQ LMPI Sbjct: 240 HVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPI 299 Query: 301 TRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPP 360 T IA KVQQKRL KTSRCG WAR N+F DTWA ++DTVLKHLRAS KKLTRKQGDLPPP Sbjct: 300 TSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359 Query: 361 AKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGA 420 AK EQGS A RPVPASRGGKTLCKG RQAPPGPPA+F RPI SASPP A R STPCPGGA Sbjct: 360 AKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGA 419 Query: 421 VREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWV 480 VREDTYPVGTQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+ GPWF HYDF SCWV Sbjct: 420 VREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWV 479 Query: 481 RAISQEDQLAPCWQAEHPAE 500 RAISQEDQLA CWQAEH E Sbjct: 480 RAISQEDQLATCWQAEHCGE 499 >gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 [Homo sapiens] Length = 424 Score = 495 bits (1275), Expect = e-140 Identities = 230/240 (95%), Positives = 232/240 (96%) Query: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 369 KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA Sbjct: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244 Query: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429 SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG Sbjct: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304 Query: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV PWFR YDFRQSCWVRAISQEDQ Sbjct: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364 Query: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549 A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF Sbjct: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424 Score = 310 bits (794), Expect = 2e-84 Identities = 143/165 (86%), Positives = 157/165 (95%) Query: 1 MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60 MDVVEV GSWWAQEREDIIMKYEKGH+AGLPEDKGPKPF SYNNN+DH G+ HETELPPL Sbjct: 1 MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60 Query: 61 TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120 TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+ Sbjct: 61 TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120 Query: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGT 165 KLKNPGRYQIMKEKGKRSSEHIQ++D D+SGTLR+H+FFRDRYGT Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165 >gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] Length = 828 Score = 244 bits (623), Expect = 1e-64 Identities = 147/434 (33%), Positives = 217/434 (50%), Gaps = 25/434 (5%) Query: 12 AQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRRE 71 AQER +I+ KY++G + E + Y D G +HE ELP +Q E Sbjct: 12 AQERAEIVAKYDRGREGAEIEPWEDADYLVYKVT-DRFGFLHEEELPDHNVAVERQKHLE 70 Query: 72 ISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131 I R +KW+ ML WEKYK++ K R YKG+P+ +RG +W++LL I +MK + Y + Sbjct: 71 IERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKL 130 Query: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191 K + + S I++ID D++ T R H+ FRDRYG KQ+ L H+L AY YN EVGYC+ +S Sbjct: 131 KHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMS 190 Query: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251 I AL L+Y+ EEDAFWALV+L + +H++ GF + Q+ E ++ K Sbjct: 191 QITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLK 250 Query: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKR 311 H D +++ + + +D L LR+WD+Y+ EGE+ L ++ K+ +K Sbjct: 251 QHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKH 310 Query: 312 LTKTSRCGPWARFCNRFVDTWARD----EDTVLKHLRASMKKLTRKQGDLPPPAK----P 363 L K S F +T A+D +D V++ L+ SM +L R + DLP P K P Sbjct: 311 LMKLS----MEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYP 366 Query: 364 EQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVRE 423 ++ P S G L G R G P SP + R + P Sbjct: 367 KKPLGQLPPELQSWGVHHLSNGQRSV--GRP----------SPLASGRRESGAPHRRHEH 414 Query: 424 DTYPVGTQGVPSPA 437 +P G P A Sbjct: 415 SPHPQSRTGTPERA 428 >gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] Length = 845 Score = 244 bits (623), Expect = 1e-64 Identities = 147/434 (33%), Positives = 217/434 (50%), Gaps = 25/434 (5%) Query: 12 AQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRRE 71 AQER +I+ KY++G + E + Y D G +HE ELP +Q E Sbjct: 29 AQERAEIVAKYDRGREGAEIEPWEDADYLVYKVT-DRFGFLHEEELPDHNVAVERQKHLE 87 Query: 72 ISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131 I R +KW+ ML WEKYK++ K R YKG+P+ +RG +W++LL I +MK + Y + Sbjct: 88 IERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKL 147 Query: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191 K + + S I++ID D++ T R H+ FRDRYG KQ+ L H+L AY YN EVGYC+ +S Sbjct: 148 KHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMS 207 Query: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251 I AL L+Y+ EEDAFWALV+L + +H++ GF + Q+ E ++ K Sbjct: 208 QITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLK 267 Query: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKR 311 H D +++ + + +D L LR+WD+Y+ EGE+ L ++ K+ +K Sbjct: 268 QHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKH 327 Query: 312 LTKTSRCGPWARFCNRFVDTWARD----EDTVLKHLRASMKKLTRKQGDLPPPAK----P 363 L K S F +T A+D +D V++ L+ SM +L R + DLP P K P Sbjct: 328 LMKLS----MEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYP 383 Query: 364 EQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVRE 423 ++ P S G L G R G P SP + R + P Sbjct: 384 KKPLGQLPPELQSWGVHHLSNGQRSV--GRP----------SPLASGRRESGAPHRRHEH 431 Query: 424 DTYPVGTQGVPSPA 437 +P G P A Sbjct: 432 SPHPQSRTGTPERA 445 >gi|148235002 TBC1 domain family, member 26 [Homo sapiens] Length = 250 Score = 236 bits (602), Expect = 4e-62 Identities = 121/206 (58%), Positives = 148/206 (71%), Gaps = 5/206 (2%) Query: 18 IIMKYEKGHQAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75 II KYE+GH+AG D G + R Y NN LGIVHE ELP ++A E KQ R+E R Sbjct: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75 Query: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135 +KW ML DW KY+S++KL R YK +P+ +RG WS+LL+I+ +K +NPG+Y++MKEKG Sbjct: 76 NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135 Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195 KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNPEVGY RDLS I A Sbjct: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195 Query: 196 LFLLYLPEEDAFWALVQLLASERHSL 221 + LL LPEEDAFWAL QLLA ERHSL Sbjct: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221 >gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo sapiens] Length = 279 Score = 186 bits (472), Expect = 5e-47 Identities = 105/209 (50%), Positives = 122/209 (58%), Gaps = 22/209 (10%) Query: 279 LGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDT 338 +GL R + G PI + K L K SR G WARF ++F TWA D D Sbjct: 79 VGLPRRRSGLVSRAGHSDAEPIPHVTQMKVGKHLMKASRSGLWARFQDQFPQTWALDSDA 138 Query: 339 VLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASR-GGKTLCKGDRQAPPGPPARF 397 VL+HL+AS+ +KP+QGSSA RP AS G KTLCKG RQAPPGP A F Sbjct: 139 VLRHLQASVL------------SKPKQGSSAPRPELASPCGRKTLCKGSRQAPPGPQAHF 186 Query: 398 PRPIWSASPPRAPRSSTPCPGGAVREDTYPVG-TQGVPSPALAQGGPQGSWRFLQWNSMP 456 + IWSASPP P TPCP VG +QGVP A AQGGP+ SWR+LQWNS+P Sbjct: 187 QQCIWSASPPWVPLPFTPCP--------VLVGLSQGVPRLAPAQGGPRVSWRYLQWNSLP 238 Query: 457 RLPTDLDVEGPWFRHYDFRQSCWVRAISQ 485 +LP D DV PWF HYDF Q CW R S+ Sbjct: 239 QLPMDSDVVSPWFPHYDFEQGCWARVPSK 267 >gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens] Length = 167 Score = 181 bits (460), Expect = 1e-45 Identities = 97/174 (55%), Positives = 111/174 (63%), Gaps = 22/174 (12%) Query: 314 KTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPV 373 K SR G WARF ++F TWA D D VL+HL+AS+ +KP+QGSSA RP Sbjct: 2 KASRSGLWARFQDQFPQTWALDSDAVLRHLQASVL------------SKPKQGSSAPRPE 49 Query: 374 PASR-GGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG-TQ 431 AS G KTLCKG RQAPPGP A F + IWSASPP P TPCP VG +Q Sbjct: 50 LASPCGRKTLCKGSRQAPPGPQAHFQQRIWSASPPWVPLPFTPCP--------VLVGLSQ 101 Query: 432 GVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQ 485 GVP A AQGGP+ SWR+LQWNS+P+LP D DV PWF HYDF Q CW R S+ Sbjct: 102 GVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFEQGCWARVPSK 155 >gi|239756750 PREDICTED: similar to TBC1 domain family, member 28 [Homo sapiens] Length = 234 Score = 169 bits (428), Expect = 6e-42 Identities = 88/167 (52%), Positives = 115/167 (68%), Gaps = 5/167 (2%) Query: 18 IIMKYEKGHQAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75 II KYE+GH+AG D G + R Y NN LGIVHE ELP ++A E KQ R+E R Sbjct: 43 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPHVSALEVKQRRKESKRT 99 Query: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135 +KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG Sbjct: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159 Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182 KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNP Sbjct: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 206 >gi|151108489 TBC1 domain family, member 28 [Homo sapiens] Length = 210 Score = 169 bits (428), Expect = 6e-42 Identities = 88/167 (52%), Positives = 115/167 (68%), Gaps = 5/167 (2%) Query: 18 IIMKYEKGHQAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75 II KYE+GH+AG D G + R Y NN LGIVHE ELP ++A E KQ R+E R Sbjct: 19 IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75 Query: 76 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135 +KW ML DW KY+S++KL R K +P+ +RG S+LL+I+++K +NPG+Y++MKEKG Sbjct: 76 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135 Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNP 182 KRSS I I D+S TL+KHM F R+G KQ+EL IL+AY YNP Sbjct: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNP 182 >gi|239751314 PREDICTED: hypothetical protein XP_002347802 [Homo sapiens] Length = 179 Score = 154 bits (389), Expect = 2e-37 Identities = 93/190 (48%), Positives = 108/190 (56%), Gaps = 27/190 (14%) Query: 300 ITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDE--DTVLKHLRASMKKLTRKQGDL 357 + R AFKVQ+ + T C W + A+ + TV L +S Sbjct: 1 MARTAFKVQRSKST----CAQWGLGSSGVRPRLAQGQLPHTVPMFLCSS----------- 45 Query: 358 PPPAKPEQGSSASRPVPASR-GGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPC 416 P AKP+QGSSA RP AS G KTLCKG RQAPPGP A F + IWSASPP P TPC Sbjct: 46 PEEAKPKQGSSAPRPELASPCGRKTLCKGSRQAPPGPQAHFQQCIWSASPPWVPLPFTPC 105 Query: 417 PGGAVREDTYPVG-TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFR 475 P VG +QGVP A AQGGP+ SWR+LQWNS+P+LP D DV PWF HYDF Sbjct: 106 P--------VLVGLSQGVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFE 157 Query: 476 QSCWVRAISQ 485 Q CW R S+ Sbjct: 158 QGCWARVPSK 167 >gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo sapiens] Length = 339 Score = 130 bits (327), Expect = 3e-30 Identities = 91/217 (41%), Positives = 121/217 (55%), Gaps = 22/217 (10%) Query: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242 EVGY RDLS A+ LLYLPEEDAFW V A+ R PN ++ L QE V Sbjct: 56 EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104 Query: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302 + S PK M K+ LC + S L L++ +DG S GLTLRLWDV ++EGEQ L + Sbjct: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164 Query: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362 +FK+ ++ L K S W F R +WA ++++VL++L+ SMK+LT+K DLP P Sbjct: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223 Query: 363 PEQGSSASRPVPA----SRGGKTLC----KGDRQAPP 391 Q +A R A S+ GK C GD +A P Sbjct: 224 LLQ--NAHRCTIAWGLQSKAGKNSCTSRASGDFRAHP 258 >gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo sapiens] Length = 617 Score = 130 bits (326), Expect = 4e-30 Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%) Query: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242 EVGY RDLS A+ LLYLPEEDAFW V A+ R PN ++ L QE V Sbjct: 186 EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 234 Query: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302 + S PK M K+ LC + S L L++ +DG S GLTLRLWDV ++EGEQ L + Sbjct: 235 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 294 Query: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362 +FK+ ++ L K S W F R +WA ++++VL++L+ SMK+LT+K DLP P Sbjct: 295 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 353 Query: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391 Q + S+ GK C GD +A P Sbjct: 354 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 388 >gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo sapiens] Length = 339 Score = 130 bits (326), Expect = 4e-30 Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%) Query: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242 EVGY RDLS A+ LLYLPEEDAFW V A+ R PN ++ L QE V Sbjct: 56 EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104 Query: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302 + S PK M K+ LC + S L L++ +DG S GLTLRLWDV ++EGEQ L + Sbjct: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164 Query: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362 +FK+ ++ L K S W F R +WA ++++VL++L+ SMK+LT+K DLP P Sbjct: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223 Query: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391 Q + S+ GK C GD +A P Sbjct: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258 >gi|167614488 TBC1 domain family, member 10B [Homo sapiens] Length = 808 Score = 107 bits (267), Expect = 3e-23 Identities = 99/398 (24%), Positives = 167/398 (41%), Gaps = 36/398 (9%) Query: 74 RKSKWVDMLGDWEKYKSSR--KLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131 R+ KW+DM +W+K+ S R K+ R KG+P ++R W L N +E+ +NPG+++ + Sbjct: 331 RELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEEL 390 Query: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191 E+ + + I++D+ H F R G Q++L IL AY Y P+ GYC+ + Sbjct: 391 -ERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQA 449 Query: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251 +AA+ L+++P E AFW LVQ+ L G++S +Q + ++ + P Sbjct: 450 PVAAVLLMHMPAEQAFWCLVQICDK---YLPGYYSAGLEAIQLDGEIFFALLRRASPLAH 506 Query: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKR 311 H ++ + + I + LR+WD++ EG + + + + + Sbjct: 507 RHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGS 566 Query: 312 LTKTSRCGPWAR----------------FCNRFVDTWARDEDTVLKHLRASMKKLTRKQG 355 + K C F V E + + A +KK +G Sbjct: 567 VEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRG 626 Query: 356 DLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQ---APPGPPARFPRPIWSASPPRAP-- 410 +L +P + SR + R + G + PG +R R A P P Sbjct: 627 EL--QYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVR 684 Query: 411 -RSSTPCPGGAV-REDTYPVGTQGVPSPALAQGGPQGS 446 S+ P PG V E +P +PSP P GS Sbjct: 685 RASAGPAPGPVVTAEGLHP----SLPSPT-GNSTPLGS 717 >gi|13994322 TBC1 domain family, member 10A [Homo sapiens] Length = 508 Score = 105 bits (263), Expect = 8e-23 Identities = 70/239 (29%), Positives = 120/239 (50%), Gaps = 14/239 (5%) Query: 74 RKSKWVDMLGDWEKY--KSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM 131 R+SKW+DML +W+K+ K +K+ R KG+P ++RG W L + +NPG++ + Sbjct: 82 RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDEL 141 Query: 132 KEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLS 191 + + + I+RD+ H F R G Q++L +L AY Y PE GYC+ + Sbjct: 142 -DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQA 200 Query: 192 HIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTM 251 IAA+ L+++P E AFW LVQ+ E++ L G++S +Q + ++ P Sbjct: 201 PIAAVLLMHMPAEQAFWCLVQI--CEKY-LPGYYSEKLEAIQLDGEILFSLLQKVSPVAH 257 Query: 252 GHQDKKDLCGQCSPLGCLIRILIDGISLGL----TLRLWDVYLVEGEQALMPITRIAFK 306 H ++ + PL + + S L LR+WD++ EG + + + + K Sbjct: 258 KHLSRQKI----DPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312 >gi|38348348 TBC1 domain family, member 10C [Homo sapiens] Length = 446 Score = 105 bits (261), Expect = 1e-22 Identities = 78/286 (27%), Positives = 126/286 (44%), Gaps = 16/286 (5%) Query: 32 EDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSS 91 E GP P+R D G + + P + R+ R+ KWV+M WEK S Sbjct: 27 ELSGPGPYRQ----ADRYGFIGGSSAEPGPGHPPADLIRQ--REMKWVEMTSHWEKTMSR 80 Query: 92 R--KLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDI 149 R K+ + KG+P +R W +L + +PG YQ + E + ++ I RD+ Sbjct: 81 RYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELAE-APGDPQWMETIGRDL 139 Query: 150 SGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWA 209 H F G Q+ LL +L AY Y PE GYC+ +AA+ L++LP E+AFW Sbjct: 140 HRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWC 199 Query: 210 LVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCL 269 LVQ+ L G++ P+ V+ + ++ P H + + Sbjct: 200 LVQIC---EVYLPGYYGPHMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWF 256 Query: 270 IRILIDGISLGLTLRLWDVYLVEGEQAL----MPITRIAFKVQQKR 311 + + + LR+WD +L EG + L + + R+A ++R Sbjct: 257 LCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVRLALGTAEQR 302 >gi|68299759 ecotropic viral integration site 5 [Homo sapiens] Length = 810 Score = 88.2 bits (217), Expect = 2e-17 Identities = 59/249 (23%), Positives = 115/249 (46%), Gaps = 9/249 (3%) Query: 78 WVDMLGDWE--KYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135 W ++ +WE + K +++ + +KG+P + R +W +L + + M +K+ E Sbjct: 138 WGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQSMPIKDQ-----YSELL 192 Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195 K +S + I RDI+ T +H FF+++ Q L +++ AY + EVGYC+ + I Sbjct: 193 KMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVG 252 Query: 196 LFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQD 255 L L+ +PEE+AF V+L+ R L+ P+ + Q E ++ P+ H Sbjct: 253 LLLMQMPEEEAFCVFVKLMQDYR--LRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQ 310 Query: 256 KKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKT 315 + + I + L + R++D+++ EG + + + ++ Q L + Sbjct: 311 SQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQL 370 Query: 316 SRCGPWARF 324 G F Sbjct: 371 DMEGMLQHF 379 >gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] Length = 963 Score = 85.5 bits (210), Expect = 1e-16 Identities = 59/254 (23%), Positives = 122/254 (48%), Gaps = 14/254 (5%) Query: 70 REISRKSKWVDMLGDW--EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKN--- 124 +E+S KW + + S +L + G+P R +W ++ K K+ Sbjct: 629 QEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTE 688 Query: 125 PGRYQIMKEKG-KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPE 183 PG +Q + +K ++ + ++I+ D+ TL + + ++L ++LLA+ NP+ Sbjct: 689 PGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPD 748 Query: 184 VGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQ---E 240 +GYC+ L+ + A+ LLYL +EDAFW LV ++ E + +++ T+ G Q Q Sbjct: 749 IGYCQGLNRLVAVALLYLEQEDAFWCLVTIV--EVFMPRDYYTK---TLLGSQVDQRVFR 803 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 +++ P+ GH ++ + + + +D + + ++WD +L EG + + Sbjct: 804 DLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRF 863 Query: 301 TRIAFKVQQKRLTK 314 FK +++ + K Sbjct: 864 ALALFKYKEEEILK 877 >gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] Length = 914 Score = 85.5 bits (210), Expect = 1e-16 Identities = 59/254 (23%), Positives = 122/254 (48%), Gaps = 14/254 (5%) Query: 70 REISRKSKWVDMLGDW--EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKN--- 124 +E+S KW + + S +L + G+P R +W ++ K K+ Sbjct: 629 QEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTE 688 Query: 125 PGRYQIMKEKG-KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPE 183 PG +Q + +K ++ + ++I+ D+ TL + + ++L ++LLA+ NP+ Sbjct: 689 PGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPD 748 Query: 184 VGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQ---E 240 +GYC+ L+ + A+ LLYL +EDAFW LV ++ E + +++ T+ G Q Q Sbjct: 749 IGYCQGLNRLVAVALLYLEQEDAFWCLVTIV--EVFMPRDYYTK---TLLGSQVDQRVFR 803 Query: 241 HVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPI 300 +++ P+ GH ++ + + + +D + + ++WD +L EG + + Sbjct: 804 DLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRF 863 Query: 301 TRIAFKVQQKRLTK 314 FK +++ + K Sbjct: 864 ALALFKYKEEEILK 877 >gi|229577000 ecotropic viral integration site 5-like isoform 1 [Homo sapiens] Length = 805 Score = 85.1 bits (209), Expect = 1e-16 Identities = 58/237 (24%), Positives = 111/237 (46%), Gaps = 9/237 (3%) Query: 78 WVDMLGDWEKYKSSRK--LIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135 W + +WE+++ ++ L + KG+P + R +W +L + +M +KN E Sbjct: 90 WGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQ-----YSELL 144 Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195 K SS + I RDI+ T +H FF+ + Q L +++ AY + EVGYC+ + I Sbjct: 145 KMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVG 204 Query: 196 LFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQD 255 L L+ +PEE+AF V+L+ + + L+ P+ + Q E+++ P H Sbjct: 205 LLLMQMPEEEAFCVFVRLM--QEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFR 262 Query: 256 KKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRL 312 + + + + L + R++D+++ EG + + + +V Q L Sbjct: 263 SQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAEL 319 >gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo sapiens] Length = 794 Score = 85.1 bits (209), Expect = 1e-16 Identities = 58/237 (24%), Positives = 111/237 (46%), Gaps = 9/237 (3%) Query: 78 WVDMLGDWEKYKSSRK--LIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135 W + +WE+++ ++ L + KG+P + R +W +L + +M +KN E Sbjct: 90 WGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQ-----YSELL 144 Query: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195 K SS + I RDI+ T +H FF+ + Q L +++ AY + EVGYC+ + I Sbjct: 145 KMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVG 204 Query: 196 LFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQD 255 L L+ +PEE+AF V+L+ + + L+ P+ + Q E+++ P H Sbjct: 205 LLLMQMPEEEAFCVFVRLM--QEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFR 262 Query: 256 KKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRL 312 + + + + L + R++D+++ EG + + + +V Q L Sbjct: 263 SQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAEL 319 >gi|7661586 TBC1 domain family, member 29 [Homo sapiens] Length = 150 Score = 83.6 bits (205), Expect = 4e-16 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 10/137 (7%) Query: 251 MGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQK 310 MGH DK+ LC Q S L+R+L DGISLGLT LWD+YL+EGEQ LM IT IAFKVQ+ Sbjct: 1 MGHLDKEGLCTQGSSFSWLLRVLNDGISLGLTPCLWDMYLLEGEQMLMLITSIAFKVQRS 60 Query: 311 RLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSAS 370 +T++ W R + R + + L +S++ LT + +G S Sbjct: 61 LYEETNK-ETWGPATPRALKGTGRAR-PICESLHSSLQALTASES--------SRGPSLL 110 Query: 371 RPVPASRGGKTLCKGDR 387 + P G + L +GD+ Sbjct: 111 QTPPRVPGQQALSRGDK 127 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,933,054 Number of Sequences: 37866 Number of extensions: 1474346 Number of successful extensions: 8108 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 119 Number of HSP's successfully gapped in prelim test: 461 Number of HSP's that attempted gapping in prelim test: 6718 Number of HSP's gapped (non-prelim): 1557 length of query: 549 length of database: 18,247,518 effective HSP length: 107 effective length of query: 442 effective length of database: 14,195,856 effective search space: 6274568352 effective search space used: 6274568352 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.