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Search of human proteins with 226528968
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226528968 coiled-coil domain containing 42 isoform 2 [Homo
sapiens]
(242 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226528968 coiled-coil domain containing 42 isoform 2 [Homo sa... 475 e-134
gi|226494053 coiled-coil domain containing 42 isoform 1 [Homo sa... 339 1e-93
gi|221554526 coiled-coil domain containing 42B [Homo sapiens] 93 2e-19
gi|217272874 coiled-coil domain containing 37 [Homo sapiens] 53 3e-07
gi|226491199 coiled-coil domain containing 38 [Homo sapiens] 47 2e-05
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 43 2e-04
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 43 2e-04
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 43 2e-04
gi|110611228 utrophin [Homo sapiens] 42 4e-04
gi|71061468 centromere protein E [Homo sapiens] 42 4e-04
gi|38044112 restin isoform b [Homo sapiens] 42 6e-04
gi|4506751 restin isoform a [Homo sapiens] 42 6e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 41 8e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 41 8e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 41 8e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 41 8e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 41 8e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 40 0.001
gi|16262452 cingulin [Homo sapiens] 40 0.002
gi|40538794 coiled-coil domain containing 21 [Homo sapiens] 40 0.002
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 40 0.002
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 40 0.002
gi|31982906 cingulin-like 1 [Homo sapiens] 40 0.002
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 40 0.002
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 40 0.002
gi|41349446 stromal interaction molecule 2 [Homo sapiens] 39 0.003
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 39 0.003
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 39 0.003
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 39 0.003
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 39 0.003
>gi|226528968 coiled-coil domain containing 42 isoform 2 [Homo
sapiens]
Length = 242
Score = 475 bits (1222), Expect = e-134
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MSLGIMEEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQ 60
MSLGIMEEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQ
Sbjct: 1 MSLGIMEEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQ 60
Query: 61 KKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQ 120
KKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQ
Sbjct: 61 KKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQ 120
Query: 121 HMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTL 180
HMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTL
Sbjct: 121 HMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTL 180
Query: 181 LLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRV 240
LLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRV
Sbjct: 181 LLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRV 240
Query: 241 RI 242
RI
Sbjct: 241 RI 242
>gi|226494053 coiled-coil domain containing 42 isoform 1 [Homo
sapiens]
Length = 316
Score = 339 bits (869), Expect = 1e-93
Identities = 201/317 (63%), Positives = 220/317 (69%), Gaps = 76/317 (23%)
Query: 1 MSLGIMEEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQ 60
MSLGIMEEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQ
Sbjct: 1 MSLGIMEEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQ 60
Query: 61 KKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRA------------- 107
KKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRA
Sbjct: 61 KKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQ 120
Query: 108 -MKKANKERE----LKCQHMQ----------------------------ELTKRKQEMVA 134
M++ K ++ L+ +H + E+ R + +V+
Sbjct: 121 HMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEFEEIHEVIARYKTLVS 180
Query: 135 LRLEH-----------QRLSAKLKDYYIFNKYLEKVVENSE------------------E 165
+R + +R A+L Y + K E + +N+E E
Sbjct: 181 MRHDLMQSAQEGQEKIERAKARLARY-MEEKDDEILQQNNELARLQMRFDRARSNVIFWE 239
Query: 166 SRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDR 225
SRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDR
Sbjct: 240 SRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDR 299
Query: 226 SDIWAEVKKKEQQRVRI 242
SDIWAEVKKKEQQRVRI
Sbjct: 300 SDIWAEVKKKEQQRVRI 316
>gi|221554526 coiled-coil domain containing 42B [Homo sapiens]
Length = 308
Score = 92.8 bits (229), Expect = 2e-19
Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 78/299 (26%)
Query: 13 EYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETL 72
EYFRL E+L KLP P + LLEK++E Q + +K++F+ + L
Sbjct: 7 EYFRLALQEKLST---KLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAAL 63
Query: 73 NLRWEELGVKEAQLKAHIQKSEQFIQEND------------------QKRIRAMKKANKE 114
RWE+L KE +LK + ++F+Q+++ ++ + A++ +
Sbjct: 64 KQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQL 123
Query: 115 RELKCQH--MQELTKRKQ--------------------EMVA-----------LRLEHQR 141
+EL+ +H +Q KR + E+VA LRL +
Sbjct: 124 QELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLRERE 183
Query: 142 LSAKLKD-----YYIFNKYLEKVVENSE-------------------ESRWAHIQNTAAK 177
A+L+ + + + ++V+ + ES+W IQNTAA+
Sbjct: 184 QLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAE 243
Query: 178 KTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKE 236
KTLLLG +MA LNLFQ+V +H + + +EDT QL+ ++ F+QD S + A + + E
Sbjct: 244 KTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKLFMQDLSAMLAGLGQAE 302
>gi|217272874 coiled-coil domain containing 37 [Homo sapiens]
Length = 611
Score = 52.8 bits (125), Expect = 3e-07
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 25/163 (15%)
Query: 22 RLLQMLQKLPNVEGASESP--------SIWLL----EKKKETEIMHQTMVQKKKMFQ--- 66
R LQ+ K ++E +E+ + W L EK E E M + QK++MF
Sbjct: 104 RQLQLEDKQEDLEARAEAEHQRAFRDYTTWKLTLTKEKNVEPENMSGYIKQKRQMFLLQY 163
Query: 67 ---------RRMETLNLRWE-ELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERE 116
+R+ETL + E L E L+ ++F++END ++AM+ A KE +
Sbjct: 164 ALDVKRREIQRLETLATKEEARLERAEKSLEKDAALFDEFVRENDCSSVQAMRAAEKETK 223
Query: 117 LKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKV 159
K + + E+ ++V ++ E R LK Y ++ +L K+
Sbjct: 224 AKIEKILEIRDLTTQIVNIKSEISRFEDTLKHYKVYKDFLYKL 266
>gi|226491199 coiled-coil domain containing 38 [Homo sapiens]
Length = 563
Score = 46.6 bits (109), Expect = 2e-05
Identities = 28/125 (22%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
Query: 33 VEGASESPSIW-LLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQ 91
+EG+ ++ + +++ ++ + K+ ++ + + +R +L E +L+
Sbjct: 100 IEGSDTKRTVHEFINDQRDRFLLEYALSTKRNTIKKFEKDIAMRERQLKKAEKKLQDDAL 159
Query: 92 KSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYYI 151
E+F++ENDQ+ + A+K A +E K Q EL K E+ A++ E + L++Y
Sbjct: 160 AFEEFLRENDQRSVDALKMAAQETINKLQMTAELKKASMEVQAVKSEIAKTEFLLREYMK 219
Query: 152 FNKYL 156
+ +L
Sbjct: 220 YGFFL 224
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 43.1 bits (100), Expect = 2e-04
Identities = 56/242 (23%), Positives = 104/242 (42%), Gaps = 46/242 (19%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEK------KKETEIMHQTMVQKKKMFQRRMETLNL 74
+RLL++L+++ N E + I LE+ KK + H+ V+KKK Q +E
Sbjct: 759 DRLLEILKEVEN-EKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQM-LEEARR 816
Query: 75 RWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQ----------- 123
R + L QL+ ++K + I+E ++ +R + ERE+ +
Sbjct: 817 REDNLNDSSQQLQDSLRKKDDRIEELEE-ALRESVQITAEREMVLAQEESARTNAEKQVE 875
Query: 124 ------ELTKRKQEMVALRLEHQRLSAKLKDYYIFN------KYLEKVVENSEESRWAHI 171
E K++ E + +L + S K+ ++ N K+LE+V+E +E+ A I
Sbjct: 876 ELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAI 935
Query: 172 QNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVAL--EDTHKQLDMIQQFIQDRSDIW 229
K A + L ++ S K EVA + + + ++Q Q+R +
Sbjct: 936 SE------------KDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLM 983
Query: 230 AE 231
A+
Sbjct: 984 AD 985
Score = 39.7 bits (91), Expect = 0.002
Identities = 41/189 (21%), Positives = 83/189 (43%), Gaps = 18/189 (9%)
Query: 46 EKKKETEIMH---QTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQ 102
E+ K+ E+ + M K + + + + +WEEL K A L+A I + +Q + D
Sbjct: 421 EEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDT 480
Query: 103 KRIRAMKK----ANKERELKCQHM----QELTKRKQEMVALRLEHQRLSAKLKDYYIFNK 154
+ + K N+ + K QH+ + LT ++Q L+ E L +L++
Sbjct: 481 ELLALQTKLETLTNQFSDSK-QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLN 539
Query: 155 YLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQ 214
K +++ E + K +L +K +N+ Q ++L+E L D KQ
Sbjct: 540 KKTKQIQDMAEEKGTQAGEIHDLKDML--DVKERKVNVLQKKIENLQE----QLRDKEKQ 593
Query: 215 LDMIQQFIQ 223
+ +++ ++
Sbjct: 594 MSSLKERVK 602
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 43.1 bits (100), Expect = 2e-04
Identities = 56/242 (23%), Positives = 104/242 (42%), Gaps = 46/242 (19%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEK------KKETEIMHQTMVQKKKMFQRRMETLNL 74
+RLL++L+++ N E + I LE+ KK + H+ V+KKK Q +E
Sbjct: 731 DRLLEILKEVEN-EKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQM-LEEARR 788
Query: 75 RWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQ----------- 123
R + L QL+ ++K + I+E ++ +R + ERE+ +
Sbjct: 789 REDNLNDSSQQLQDSLRKKDDRIEELEE-ALRESVQITAEREMVLAQEESARTNAEKQVE 847
Query: 124 ------ELTKRKQEMVALRLEHQRLSAKLKDYYIFN------KYLEKVVENSEESRWAHI 171
E K++ E + +L + S K+ ++ N K+LE+V+E +E+ A I
Sbjct: 848 ELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAI 907
Query: 172 QNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVAL--EDTHKQLDMIQQFIQDRSDIW 229
K A + L ++ S K EVA + + + ++Q Q+R +
Sbjct: 908 SE------------KDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLM 955
Query: 230 AE 231
A+
Sbjct: 956 AD 957
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 43.1 bits (100), Expect = 2e-04
Identities = 56/227 (24%), Positives = 107/227 (47%), Gaps = 24/227 (10%)
Query: 28 QKLPNVEGASESPSIWLLEKKKETEIMHQTMVQK-KKMFQRRMETLNLRWE-ELGVKEAQ 85
QK +V G S L EK++E E H+ + K K+ Q+ M ++E E + A+
Sbjct: 820 QKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAE 879
Query: 86 LKAHI-----------QKSEQFIQENDQKRIRAMKKANKERELKCQHMQ-ELTKRKQEMV 133
L H+ ++ + +++ KR+ +++ ++E+E K Q ++ +L R +++
Sbjct: 880 LLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVK 939
Query: 134 A--LRLEHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKK--TLLLGTIKMAT 189
A LE Q +A+ + + + +V SEE+ H Q A+K T LL + +
Sbjct: 940 ARLALLEVQEETARREKQQLLD-VQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR 998
Query: 190 LNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKE 236
L ++ ++ LK ++V L QQ + S + AE +KK+
Sbjct: 999 EILDELQARKLKLESQVDLLQAQS-----QQLQKHFSSLEAEAQKKQ 1040
Score = 28.5 bits (62), Expect = 5.5
Identities = 40/184 (21%), Positives = 83/184 (45%), Gaps = 21/184 (11%)
Query: 8 EEDLAEYFRL-QYGERLLQMLQKLPNVEGASESPSIWLLEKKKE------TEIMHQTMVQ 60
+E+ E RL Q E+ L L++ ++ A E + E++ + ++ T
Sbjct: 627 QEEEEEILRLHQQKEQSLSSLRE--RLQKAIEEEEARMREEESQRLSWLRAQVQSSTQAD 684
Query: 61 KKKMFQRRMETLNLRWEELGVKEAQLKAHI-QKSEQFIQ------ENDQKRIRAMKKANK 113
+ ++ + +L EEL ++ +A + QK+ Q ++ E +K +A A K
Sbjct: 685 EDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK 744
Query: 114 ERELKCQHMQELTKRKQEMVALRLEH----QRLSAKLK-DYYIFNKYLEKVVENSEESRW 168
E+ L+ Q +RK+ + L EH +RL + L+ + L+K ++ +++
Sbjct: 745 EKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEE 804
Query: 169 AHIQ 172
A +Q
Sbjct: 805 AQLQ 808
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 42.4 bits (98), Expect = 4e-04
Identities = 44/202 (21%), Positives = 90/202 (44%), Gaps = 33/202 (16%)
Query: 60 QKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKC 119
++ M Q R++ +N RW +L K A ++AH++ S E + + ++++ K +K
Sbjct: 2524 EEATMLQHRLDDMNQRWNDLKAKSASIRAHLEAS----AEKWNRLLMSLEELIKWLNMKD 2579
Query: 120 QHMQELTKRKQEMVALRLEHQRLSA-----KLKDYYIFNK-------YLEKVVENSEESR 167
+ +++ ++ AL+L++ A K K+Y + N ++ +E EE R
Sbjct: 2580 EELKKQMPIGGDVPALQLQYDHCKALRRELKEKEYSVLNAVDQARVFLADQPIEAPEEPR 2639
Query: 168 WAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTE------VALEDTHKQLDMIQQF 221
+N +K L T + + + + K EV E + KQ+D +
Sbjct: 2640 ----RNLQSKTEL---TPEERAQKIAKAMRKQSSEVKEKWESLNAVTSNWQKQVDKALEK 2692
Query: 222 IQD----RSDIWAEVKKKEQQR 239
++D D+ A++K+ E R
Sbjct: 2693 LRDLQGAMDDLDADMKEAESVR 2714
Score = 36.2 bits (82), Expect = 0.026
Identities = 32/154 (20%), Positives = 75/154 (48%), Gaps = 17/154 (11%)
Query: 68 RMETLNLRWEELGVKEAQLKAHIQKSEQFIQE------NDQKR----IRAMKKANKEREL 117
R++ +N+ W+EL ++ LKA + + E+ + + DQK +R + ++ E+
Sbjct: 523 RLQEINILWQELLEEQCLLKAWLTEKEEALNKVQTSNFKDQKELSVSVRRLAILKEDMEM 582
Query: 118 KCQHMQELTKRKQEMVALRLEHQRLSAKL-KDYYIFNKYLEKVVENSEESRWAHIQNTAA 176
K Q + +L++ Q++ L L++ + S K+ D + + +V+ E+S N
Sbjct: 583 KRQTLDQLSEIGQDVGQL-LDNSKASKKINSDSEELTQRWDSLVQRLEDS-----SNQVT 636
Query: 177 KKTLLLGTIKMATLNLFQIVSKHLKEVTEVALED 210
+ LG ++ +L + V + +T+ + ++
Sbjct: 637 QAVAKLGMSQIPQKDLLETVRVREQAITKKSKQE 670
Score = 31.2 bits (69), Expect = 0.85
Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 5/116 (4%)
Query: 66 QRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQEL 125
Q +M LN RWE L V+ ++ + +Q+ +++ A +ER K + L
Sbjct: 391 QEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTEERIQKMETC-PL 449
Query: 126 TKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVV----ENSEESRWAHIQNTAAK 177
+ + L EH+ L + L+ + L +V ENS ES A +++ K
Sbjct: 450 DDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQK 505
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 42.4 bits (98), Expect = 4e-04
Identities = 47/215 (21%), Positives = 98/215 (45%), Gaps = 29/215 (13%)
Query: 45 LEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKR 104
+E+ + E ++ + K + + R + L E L VK QLK HI+++ IQE+ K+
Sbjct: 1328 MERLRLNEKFQESQEEIKSLTKER-DNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQ 1386
Query: 105 IRAMKKANKERELK--CQHMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNK-------- 154
+++ K+ E M++ + ++ + +E LS +L++ + K
Sbjct: 1387 EQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDD 1446
Query: 155 --YLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMA---------TLNLFQIVSKHLKEV 203
L++V+++ + +I+ AK +K+A T+N ++ +L E
Sbjct: 1447 LQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRV---NLSE- 1502
Query: 204 TEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQ 238
E + KQL+ I +Q++ E+ +KE+Q
Sbjct: 1503 KETEISTIQKQLEAINDKLQNKIQ---EIYEKEEQ 1534
Score = 35.8 bits (81), Expect = 0.034
Identities = 69/278 (24%), Positives = 116/278 (41%), Gaps = 43/278 (15%)
Query: 2 SLGIMEEE------DLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMH 55
SLG ++ E +L E R + ERL +M Q +E + EK TE +
Sbjct: 860 SLGALKTELSYKTQELQEKTR-EVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQ 918
Query: 56 QTMVQKKKMFQRRMETLNLRWEELGVKEAQLKA--------HIQKSEQFIQ-----ENDQ 102
QT+ + K + Q + + L+ E L ++ QLK+ +I EQ + Q
Sbjct: 919 QTLEEVKTLTQEKDDLKQLQ-ESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQ 977
Query: 103 KRIRAMKKANKERELKCQHMQELT-----KRKQEMVALRLEH-------QRLSAKLKDYY 150
+ I +K E + HM+E T + +Q+MV + + Q L+A +KD
Sbjct: 978 ETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNE 1037
Query: 151 IF---NKYLEKVVENSEESRWAH--IQNTAAKKTLLLGTIKMATLNL--FQIVSKHLKEV 203
I K + E +E + I KT L I+M N +++ LK+
Sbjct: 1038 IIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQ 1097
Query: 204 TE-VALEDTH--KQLDMIQQFIQDRSDIWAEVKKKEQQ 238
E VA E H K+ + + +++ ++K+K QQ
Sbjct: 1098 QEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQ 1135
Score = 35.8 bits (81), Expect = 0.034
Identities = 39/193 (20%), Positives = 85/193 (44%), Gaps = 23/193 (11%)
Query: 49 KETEIMHQ-----TMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQK 103
K+ EI+ Q +++Q+K Q+ +E++ + KE QLK ++++ + EN ++
Sbjct: 1034 KDNEIIEQQRKIFSLIQEKNELQQMLESV------IAEKE-QLKTDLKENIEMTIENQEE 1086
Query: 104 RIRAMKKANKERELKCQHMQELTKRKQEM---------VALRLEHQRLSAKLKDYYIFNK 154
+ K++E+ Q K++ E+ V +L+ + + K + N
Sbjct: 1087 LRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNV 1146
Query: 155 YLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQ 214
E + + +++N K L L ++ L L Q ++++ +EV + E K
Sbjct: 1147 QEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKE--RKV 1204
Query: 215 LDMIQQFIQDRSD 227
L +Q+ + D
Sbjct: 1205 LKELQKSFETERD 1217
Score = 32.0 bits (71), Expect = 0.50
Identities = 44/215 (20%), Positives = 90/215 (41%), Gaps = 33/215 (15%)
Query: 29 KLPNVEGASESPSIWLLEKKKETEIM-HQTMVQKKKMFQRRMETLNLRWEELGVKEAQLK 87
KL N++ E+ + L EK +E + HQ + KK + + + + + QLK
Sbjct: 1803 KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEME---------QLK 1853
Query: 88 AHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLK 147
I+ + + + + + +K ++ E M+E ++ L+LE +L L+
Sbjct: 1854 KQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQ 1913
Query: 148 DYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVA 207
+ ++R IQ +L K L + +S+ +++++
Sbjct: 1914 E---------------TKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQ 1958
Query: 208 LEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRVRI 242
+D K D +Q+ IQ E++KKE Q +R+
Sbjct: 1959 -KDLDKSKDELQKKIQ-------ELQKKELQLLRV 1985
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 41.6 bits (96), Expect = 6e-04
Identities = 53/223 (23%), Positives = 102/223 (45%), Gaps = 37/223 (16%)
Query: 45 LEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVK--------EAQLKAHIQKSEQF 96
LEKK ET H + K ++R + EE+ E +LK +++
Sbjct: 965 LEKKMETS--HNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGL 1022
Query: 97 IQENDQKRIRAMK-KANKERELKCQHMQELTKRKQEMVALRLEHQRLSAK---------- 145
+QE ++ R +A K KA + E Q M+++TK K E +A + ++ +AK
Sbjct: 1023 LQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKE 1082
Query: 146 --LKDYYIFNKYLEKV-VENSEESRWAH----IQNTAAKKTLLLGTIKMATLNLFQIVSK 198
LK+ NK E + VEN + + ++ AA+K+ L ++ + L + + +
Sbjct: 1083 NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGR 1142
Query: 199 HLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRVR 241
EVT +H++L+ + + ++ E+KK+E + ++
Sbjct: 1143 SRDEVT------SHQKLEEERSVLNNQ---LLEMKKRESKFIK 1176
Score = 34.3 bits (77), Expect = 0.10
Identities = 24/110 (21%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 48 KKETEIMHQTMVQKKKM--FQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQK-- 103
+++ E+++Q +K+K+ Q R+E ++ +L V K+ I + E+ + Q+
Sbjct: 422 REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVA 481
Query: 104 RIRAMKKANK---ERELKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYY 150
+R ++NK + ++ +QE++ ++++ R +HQR LK+++
Sbjct: 482 ELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHF 531
Score = 33.1 bits (74), Expect = 0.22
Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 23/133 (17%)
Query: 30 LPNVEGASESPSIWLLEK------KKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKE 83
L NVE ++S + +E +KE E + Q QK + E EELG
Sbjct: 1085 LKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSR 1144
Query: 84 AQLKAHIQKSEQ-----------------FIQENDQKRIRAMKKANKERELKCQHMQELT 126
++ +H + E+ FI++ D+++ K + L + EL
Sbjct: 1145 DEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELE 1204
Query: 127 KRKQEMVALRLEH 139
K + E+ LR E+
Sbjct: 1205 KLRNEVTVLRGEN 1217
Score = 30.0 bits (66), Expect = 1.9
Identities = 47/214 (21%), Positives = 87/214 (40%), Gaps = 44/214 (20%)
Query: 54 MHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANK 113
M +++Q+ Q ++E + + LK H E+ Q+ + A +K +K
Sbjct: 498 MSLSLLQEISSLQEKLEVTRTDHQR---EITSLKEHFGAREETHQKEIKALYTATEKLSK 554
Query: 114 ERELKCQHMQELTKRKQEMVAL---RLE-----HQRLSAKLK------------DYYIFN 153
E E ++ K +++AL +LE HQ+ +LK ++
Sbjct: 555 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELK 614
Query: 154 KYLEKV----------VENSEES-RWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKE 202
+EK+ ++N ++S R AH + A + L+ IK +L I SK L +
Sbjct: 615 TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSK-LDK 673
Query: 203 VTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKE 236
+ L + L+ +Q+ AE+K KE
Sbjct: 674 AEDQHLVEMEDTLNKLQE---------AEIKVKE 698
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 41.6 bits (96), Expect = 6e-04
Identities = 53/223 (23%), Positives = 102/223 (45%), Gaps = 37/223 (16%)
Query: 45 LEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVK--------EAQLKAHIQKSEQF 96
LEKK ET H + K ++R + EE+ E +LK +++
Sbjct: 1000 LEKKMETS--HNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGL 1057
Query: 97 IQENDQKRIRAMK-KANKERELKCQHMQELTKRKQEMVALRLEHQRLSAK---------- 145
+QE ++ R +A K KA + E Q M+++TK K E +A + ++ +AK
Sbjct: 1058 LQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKE 1117
Query: 146 --LKDYYIFNKYLEKV-VENSEESRWAH----IQNTAAKKTLLLGTIKMATLNLFQIVSK 198
LK+ NK E + VEN + + ++ AA+K+ L ++ + L + + +
Sbjct: 1118 NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGR 1177
Query: 199 HLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRVR 241
EVT +H++L+ + + ++ E+KK+E + ++
Sbjct: 1178 SRDEVT------SHQKLEEERSVLNNQ---LLEMKKRESKFIK 1211
Score = 33.1 bits (74), Expect = 0.22
Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 23/133 (17%)
Query: 30 LPNVEGASESPSIWLLEK------KKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKE 83
L NVE ++S + +E +KE E + Q QK + E EELG
Sbjct: 1120 LKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSR 1179
Query: 84 AQLKAHIQKSEQ-----------------FIQENDQKRIRAMKKANKERELKCQHMQELT 126
++ +H + E+ FI++ D+++ K + L + EL
Sbjct: 1180 DEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELE 1239
Query: 127 KRKQEMVALRLEH 139
K + E+ LR E+
Sbjct: 1240 KLRNEVTVLRGEN 1252
Score = 32.0 bits (71), Expect = 0.50
Identities = 27/149 (18%), Positives = 76/149 (51%), Gaps = 8/149 (5%)
Query: 10 DLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTM--VQKKKMFQR 67
+ A+ +++ +L + +K+ +++ E SI + + +T++ H + +++ +F++
Sbjct: 418 EAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEK 477
Query: 68 -RMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQK--RIRAMKKANK---ERELKCQH 121
+ + L E+ V K+ I + E+ + Q+ +R ++NK + ++
Sbjct: 478 TKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSL 537
Query: 122 MQELTKRKQEMVALRLEHQRLSAKLKDYY 150
+QE++ ++++ R +HQR LK+++
Sbjct: 538 LQEISSLQEKLEVTRTDHQREITSLKEHF 566
Score = 30.0 bits (66), Expect = 1.9
Identities = 47/214 (21%), Positives = 87/214 (40%), Gaps = 44/214 (20%)
Query: 54 MHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANK 113
M +++Q+ Q ++E + + LK H E+ Q+ + A +K +K
Sbjct: 533 MSLSLLQEISSLQEKLEVTRTDHQR---EITSLKEHFGAREETHQKEIKALYTATEKLSK 589
Query: 114 ERELKCQHMQELTKRKQEMVAL---RLE-----HQRLSAKLK------------DYYIFN 153
E E ++ K +++AL +LE HQ+ +LK ++
Sbjct: 590 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELK 649
Query: 154 KYLEKV----------VENSEES-RWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKE 202
+EK+ ++N ++S R AH + A + L+ IK +L I SK L +
Sbjct: 650 TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSK-LDK 708
Query: 203 VTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKE 236
+ L + L+ +Q+ AE+K KE
Sbjct: 709 AEDQHLVEMEDTLNKLQE---------AEIKVKE 733
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 41.2 bits (95), Expect = 8e-04
Identities = 45/202 (22%), Positives = 92/202 (45%), Gaps = 14/202 (6%)
Query: 46 EKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKE----AQLKAHIQKSEQFIQEND 101
EKKK E Q++K+ + ET + EEL ++E AQ K + + E+ +
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEE--ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR 1802
Query: 102 QKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVE 161
++ I K ++RE M+ELTK K + + + L+ + K+ + EK+ +
Sbjct: 1803 EQLIEKKMKLAQKRERWINSMEELTKNKM----ILYQKKNLAQEKKN---LAQEKEKLAQ 1855
Query: 162 NSEESRWAHIQNTAAKKTLLLGTIKMATLN-LFQIVSKHLKEVTEVALEDTHKQLDMIQQ 220
E + + T +KK L+ K+ N + V + L + E ++ K + ++
Sbjct: 1856 RKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKK 1915
Query: 221 FIQDRSDIWAEVKKKEQQRVRI 242
+Q + + +K Q+++++
Sbjct: 1916 LVQVEDSLAKKQEKLAQEKMKL 1937
Score = 32.7 bits (73), Expect = 0.29
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Query: 12 AEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMET 71
AE R Q +L Q +KL E L + + + M Q + F ++ ET
Sbjct: 1584 AEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEET 1643
Query: 72 LNLRWEELGV---KEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKR 128
L R E+L K AQ + + K + + ++K + K + + + Q ++EL +R
Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQR 1703
Query: 129 KQEM 132
+Q +
Sbjct: 1704 EQNL 1707
Score = 29.6 bits (65), Expect = 2.5
Identities = 23/104 (22%), Positives = 46/104 (44%)
Query: 7 EEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQ 66
EEE E R + ER + + VE E EKKKE + + ++K+
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 67 RRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKK 110
ET +L EE + L+ + + ++ +++ Q +++ ++
Sbjct: 2314 SEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRR 2357
Score = 28.5 bits (62), Expect = 5.5
Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 4/126 (3%)
Query: 43 WLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQ 102
W +E E +HQ + + E L+WEE + + K +Q+ D+
Sbjct: 1485 WEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQY---KDE 1541
Query: 103 KRIRAMKKANKERELKCQHMQELTKR-KQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVE 161
+ + ++ ++E E K Q + E + ++E R+ +R A+ K K ++ +
Sbjct: 1542 EEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK 1601
Query: 162 NSEESR 167
++E R
Sbjct: 1602 LAQEER 1607
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 41.2 bits (95), Expect = 8e-04
Identities = 48/201 (23%), Positives = 87/201 (43%), Gaps = 30/201 (14%)
Query: 46 EKKKETEIMHQTMVQKKKMFQRR-METLNLRWEELGVKEAQLKAHIQK---SEQFIQEND 101
E++++ E + + ++++ +RR E L + EE K A+ + Q+ + E +
Sbjct: 806 ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEE 865
Query: 102 QKRIRAMKKANKERELKCQHMQELTK-RKQEMVAL-RLEHQRLSAKLKDYYIFNKYLEKV 159
R+R ++ K +EL+ Q +EL + R+Q+ AL RL+ Q+ +L
Sbjct: 866 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQ----------- 914
Query: 160 VENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIV------SKHLKEVTEVALEDTHK 213
++ S W NT A ++ ATL+L +I + L+E + K
Sbjct: 915 MKLPSSSTWGQQSNTTACQS-------QATLSLAEIQKLEEERERQLREEQRRQQRELMK 967
Query: 214 QLDMIQQFIQDRSDIWAEVKK 234
L QQ Q + W V K
Sbjct: 968 ALQQQQQQQQQKLSGWGNVSK 988
Score = 35.4 bits (80), Expect = 0.045
Identities = 21/86 (24%), Positives = 44/86 (51%)
Query: 82 KEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQR 141
+EA+++A ++ E+ QE +++ + + +E E K + +EL +RKQE R Q
Sbjct: 736 REAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQE 795
Query: 142 LSAKLKDYYIFNKYLEKVVENSEESR 167
++ + + + E+ + EE R
Sbjct: 796 IALRRQREEEERQQQEEALRRLEERR 821
Score = 28.1 bits (61), Expect = 7.2
Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 5/162 (3%)
Query: 24 LQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMV--QKKKMFQRRMETLNLRWEE--L 79
LQ L+K + E + K++E E Q + Q++++ +R+ E R EE L
Sbjct: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 779
Query: 80 GVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEH 139
++ + Q+ ++ ++ ++ R L+ + +E +RKQE + + E
Sbjct: 780 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 839
Query: 140 QRLSAKLKDYYIFNKYLEKVVENSEE-SRWAHIQNTAAKKTL 180
+ ++ + E + EE +R H + +K L
Sbjct: 840 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 881
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 41.2 bits (95), Expect = 8e-04
Identities = 48/201 (23%), Positives = 87/201 (43%), Gaps = 30/201 (14%)
Query: 46 EKKKETEIMHQTMVQKKKMFQRR-METLNLRWEELGVKEAQLKAHIQK---SEQFIQEND 101
E++++ E + + ++++ +RR E L + EE K A+ + Q+ + E +
Sbjct: 833 ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEE 892
Query: 102 QKRIRAMKKANKERELKCQHMQELTK-RKQEMVAL-RLEHQRLSAKLKDYYIFNKYLEKV 159
R+R ++ K +EL+ Q +EL + R+Q+ AL RL+ Q+ +L
Sbjct: 893 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQ----------- 941
Query: 160 VENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIV------SKHLKEVTEVALEDTHK 213
++ S W NT A ++ ATL+L +I + L+E + K
Sbjct: 942 MKLPSSSTWGQQSNTTACQS-------QATLSLAEIQKLEEERERQLREEQRRQQRELMK 994
Query: 214 QLDMIQQFIQDRSDIWAEVKK 234
L QQ Q + W V K
Sbjct: 995 ALQQQQQQQQQKLSGWGNVSK 1015
Score = 35.4 bits (80), Expect = 0.045
Identities = 21/86 (24%), Positives = 44/86 (51%)
Query: 82 KEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQR 141
+EA+++A ++ E+ QE +++ + + +E E K + +EL +RKQE R Q
Sbjct: 763 REAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQE 822
Query: 142 LSAKLKDYYIFNKYLEKVVENSEESR 167
++ + + + E+ + EE R
Sbjct: 823 IALRRQREEEERQQQEEALRRLEERR 848
Score = 28.1 bits (61), Expect = 7.2
Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 5/162 (3%)
Query: 24 LQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMV--QKKKMFQRRMETLNLRWEE--L 79
LQ L+K + E + K++E E Q + Q++++ +R+ E R EE L
Sbjct: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 806
Query: 80 GVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEH 139
++ + Q+ ++ ++ ++ R L+ + +E +RKQE + + E
Sbjct: 807 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 866
Query: 140 QRLSAKLKDYYIFNKYLEKVVENSEE-SRWAHIQNTAAKKTL 180
+ ++ + E + EE +R H + +K L
Sbjct: 867 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 908
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 41.2 bits (95), Expect = 8e-04
Identities = 48/201 (23%), Positives = 87/201 (43%), Gaps = 30/201 (14%)
Query: 46 EKKKETEIMHQTMVQKKKMFQRR-METLNLRWEELGVKEAQLKAHIQK---SEQFIQEND 101
E++++ E + + ++++ +RR E L + EE K A+ + Q+ + E +
Sbjct: 812 ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEE 871
Query: 102 QKRIRAMKKANKERELKCQHMQELTK-RKQEMVAL-RLEHQRLSAKLKDYYIFNKYLEKV 159
R+R ++ K +EL+ Q +EL + R+Q+ AL RL+ Q+ +L
Sbjct: 872 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQ----------- 920
Query: 160 VENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIV------SKHLKEVTEVALEDTHK 213
++ S W NT A ++ ATL+L +I + L+E + K
Sbjct: 921 MKLPSSSTWGQQSNTTACQS-------QATLSLAEIQKLEEERERQLREEQRRQQRELMK 973
Query: 214 QLDMIQQFIQDRSDIWAEVKK 234
L QQ Q + W V K
Sbjct: 974 ALQQQQQQQQQKLSGWGNVSK 994
Score = 35.4 bits (80), Expect = 0.045
Identities = 21/86 (24%), Positives = 44/86 (51%)
Query: 82 KEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQR 141
+EA+++A ++ E+ QE +++ + + +E E K + +EL +RKQE R Q
Sbjct: 742 REAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQE 801
Query: 142 LSAKLKDYYIFNKYLEKVVENSEESR 167
++ + + + E+ + EE R
Sbjct: 802 IALRRQREEEERQQQEEALRRLEERR 827
Score = 28.1 bits (61), Expect = 7.2
Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 5/162 (3%)
Query: 24 LQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMV--QKKKMFQRRMETLNLRWEE--L 79
LQ L+K + E + K++E E Q + Q++++ +R+ E R EE L
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 80 GVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEH 139
++ + Q+ ++ ++ ++ R L+ + +E +RKQE + + E
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845
Query: 140 QRLSAKLKDYYIFNKYLEKVVENSEE-SRWAHIQNTAAKKTL 180
+ ++ + E + EE +R H + +K L
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 41.2 bits (95), Expect = 8e-04
Identities = 48/201 (23%), Positives = 87/201 (43%), Gaps = 30/201 (14%)
Query: 46 EKKKETEIMHQTMVQKKKMFQRR-METLNLRWEELGVKEAQLKAHIQK---SEQFIQEND 101
E++++ E + + ++++ +RR E L + EE K A+ + Q+ + E +
Sbjct: 812 ERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEE 871
Query: 102 QKRIRAMKKANKERELKCQHMQELTK-RKQEMVAL-RLEHQRLSAKLKDYYIFNKYLEKV 159
R+R ++ K +EL+ Q +EL + R+Q+ AL RL+ Q+ +L
Sbjct: 872 AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQ----------- 920
Query: 160 VENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIV------SKHLKEVTEVALEDTHK 213
++ S W NT A ++ ATL+L +I + L+E + K
Sbjct: 921 MKLPSSSTWGQQSNTTACQS-------QATLSLAEIQKLEEERERQLREEQRRQQRELMK 973
Query: 214 QLDMIQQFIQDRSDIWAEVKK 234
L QQ Q + W V K
Sbjct: 974 ALQQQQQQQQQKLSGWGNVSK 994
Score = 35.4 bits (80), Expect = 0.045
Identities = 21/86 (24%), Positives = 44/86 (51%)
Query: 82 KEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQR 141
+EA+++A ++ E+ QE +++ + + +E E K + +EL +RKQE R Q
Sbjct: 742 REAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQE 801
Query: 142 LSAKLKDYYIFNKYLEKVVENSEESR 167
++ + + + E+ + EE R
Sbjct: 802 IALRRQREEEERQQQEEALRRLEERR 827
Score = 28.1 bits (61), Expect = 7.2
Identities = 32/162 (19%), Positives = 68/162 (41%), Gaps = 5/162 (3%)
Query: 24 LQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMV--QKKKMFQRRMETLNLRWEE--L 79
LQ L+K + E + K++E E Q + Q++++ +R+ E R EE L
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 80 GVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEH 139
++ + Q+ ++ ++ ++ R L+ + +E +RKQE + + E
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845
Query: 140 QRLSAKLKDYYIFNKYLEKVVENSEE-SRWAHIQNTAAKKTL 180
+ ++ + E + EE +R H + +K L
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 40.4 bits (93), Expect = 0.001
Identities = 39/225 (17%), Positives = 98/225 (43%), Gaps = 15/225 (6%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWE-EL 79
E++ + +K+ E + EK+++ + M +K++ +R+ E + WE E
Sbjct: 382 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM---WEKEE 438
Query: 80 GVKEAQLKAHIQKS--EQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRL 137
++E + K H Q+ EQ + ++++IR +K +E+E K +E + ++E + R
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKI--RE 495
Query: 138 EHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVS 197
+ +++ + + + K E+ +E W + ++ + K+
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI------HEQE 549
Query: 198 KHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRVRI 242
+ +++ E K D ++ + +W + +K +Q +I
Sbjct: 550 EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI 594
Score = 32.3 bits (72), Expect = 0.38
Identities = 35/164 (21%), Positives = 77/164 (46%), Gaps = 27/164 (16%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELG 80
E+ ++ +KL VE SE I L K+ + ++ ++ ++ Q + L +EL
Sbjct: 282 EKNAKLQEKLQLVE--SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG---KELQ 336
Query: 81 VKEAQLKAHIQKSEQFIQENDQK----------------RIRAMKKANKERELKCQHMQE 124
A+L+A ++++E + + N Q+ +I+ ++ +E+E K + +E
Sbjct: 337 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 396
Query: 125 LTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEESRW 168
+R++EM+ + E R ++ ++ K E+ + EE W
Sbjct: 397 KMRRQEEMMWEKEEKMRRQEEM----MWEK--EEKMRRQEEMMW 434
Score = 32.3 bits (72), Expect = 0.38
Identities = 27/117 (23%), Positives = 58/117 (49%), Gaps = 13/117 (11%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELG 80
E + +K+ E E +W E+K + + QK+K+ ++ + +R +E
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ--EEIWRQKEKIHEQEEK---IRKQEEK 558
Query: 81 VKEAQLKAHIQKSEQFIQENDQK------RIRAMKKANKERELKCQHMQELTKRKQE 131
+ + K H Q E+ I+E ++K +IR ++ +E+E K + +E+T+ ++E
Sbjct: 559 MWRQEEKMHDQ--EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Score = 30.0 bits (66), Expect = 1.9
Identities = 22/99 (22%), Positives = 55/99 (55%), Gaps = 10/99 (10%)
Query: 38 ESPSIWLLEKK---KETEIMHQT--MVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQK 92
+ +W E+K +E +I Q + ++++M Q + E + + E++ +E ++ Q+
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM----QE 631
Query: 93 SEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQE 131
E+ ++ ++K IR +K +E+E K + +E+ + ++E
Sbjct: 632 QEEKMRRQEEK-IREQEKKIREQEEKIREQEEMMQEQEE 669
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 40.0 bits (92), Expect = 0.002
Identities = 48/232 (20%), Positives = 101/232 (43%), Gaps = 25/232 (10%)
Query: 10 DLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRM 69
D E R +++++ KL +V+G + + L + + E++ + + K+++
Sbjct: 432 DQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVE---- 487
Query: 70 ETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRK 129
E+L ++E +L A ++ + DQ+ ++ ++ E + MQ+ T
Sbjct: 488 -------EQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDAT--- 537
Query: 130 QEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMAT 189
Q+ L E Q++SA ++ ++ E SEE+ H Q+ K L K
Sbjct: 538 QDHAVLEAERQKMSALVRGLQ------RELEETSEET--GHWQSMFQKNKEDLRATKQEL 589
Query: 190 LNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRVR 241
L L ++ + ++E +E ++L+ + D + EV KKE R +
Sbjct: 590 LQL-RMEKEEMEEELGEKIEVLQRELEQARASAGDTRQV--EVLKKELLRTQ 638
>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
Length = 762
Score = 40.0 bits (92), Expect = 0.002
Identities = 47/218 (21%), Positives = 90/218 (41%), Gaps = 27/218 (12%)
Query: 44 LLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWE----ELGVKEAQLKAHIQKSEQFIQE 99
L E ++E + QK + R L + E+ + LK +QK + +++
Sbjct: 384 LQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKK 443
Query: 100 NDQKRIRAMKKANKERELKCQHMQELTKRKQEMV----------ALRLEHQRLSAKLKDY 149
++ R++ K + KCQ E + KQ+ + +HQ+ S +LKD
Sbjct: 444 QEE-RVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDS 502
Query: 150 YIFNKYL-EKVVENSEESRWAHIQNTAAKKTLLLGTIKMA---------TLNLFQIVSKH 199
+ + L EKV E ES Q +K + L +++ +L Q V +
Sbjct: 503 ELKSTELQEKVTE--LESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEET 560
Query: 200 LKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQ 237
E EV +E K+ D +Q+ ++ + +++ + Q
Sbjct: 561 SGEGPEVEMESWQKRYDSLQKIVEKQQQKMDQLRSQVQ 598
Score = 30.4 bits (67), Expect = 1.4
Identities = 33/144 (22%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Query: 5 IMEEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKM 64
+ E E L E + E+ +Q L+ L E S L +K+ E + + +
Sbjct: 513 VTELESLLEETQAICREKEIQ-LESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMES 571
Query: 65 FQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHM-- 122
+Q+R ++L E+ K QL++ +Q EQ + + ++ +A+++ + R+ Q +
Sbjct: 572 WQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQ-EEGTSQALREEAQRRDSALQQLRT 630
Query: 123 --QELTKRKQEMVALRL---EHQR 141
+EL+ + Q+++ L EH R
Sbjct: 631 AVKELSVQNQDLIEKNLTLQEHLR 654
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 39.7 bits (91), Expect = 0.002
Identities = 67/273 (24%), Positives = 127/273 (46%), Gaps = 49/273 (17%)
Query: 3 LGIMEEE--DLAEYFRLQYG----ERLLQMLQK-------LPNVEGASESPSIWL---LE 46
+GI++ E DLA QYG +++L+ LQ+ P E E P L +E
Sbjct: 90 IGILKAEKMDLA-LLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVE 148
Query: 47 KKKET--EIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFI----QEN 100
K KE+ I+ Q +V +K RR L L E+ KE +++KS++FI QE
Sbjct: 149 KHKESYRRILGQLLVAEKS---RRQTILELEEEKRKHKE-----YMEKSDEFICLLEQEC 200
Query: 101 DQ------KRIRAMKKANKERELKCQHM-QELTKRKQEMVALRLEHQRLSAKLKDYYIFN 153
++ + I++ ++ +E+E + + +ELTK K + + E QRL+A+L +
Sbjct: 201 ERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLT---LQR 257
Query: 154 KYLEKVVENSEESRW------AHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVA 207
+ ++++ N++E+ A +Q K T L ++ T Q + ++T
Sbjct: 258 QKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNED 317
Query: 208 LEDTHKQ--LDMIQQFIQDRSDIWAEVKKKEQQ 238
++ Q L + + I + + ++K E++
Sbjct: 318 SQNRQLQQKLAALSRQIDELEETNRSLRKAEEE 350
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 39.7 bits (91), Expect = 0.002
Identities = 67/273 (24%), Positives = 127/273 (46%), Gaps = 49/273 (17%)
Query: 3 LGIMEEE--DLAEYFRLQYG----ERLLQMLQK-------LPNVEGASESPSIWL---LE 46
+GI++ E DLA QYG +++L+ LQ+ P E E P L +E
Sbjct: 90 IGILKAEKMDLA-LLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVE 148
Query: 47 KKKET--EIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFI----QEN 100
K KE+ I+ Q +V +K RR L L E+ KE +++KS++FI QE
Sbjct: 149 KHKESYRRILGQLLVAEKS---RRQTILELEEEKRKHKE-----YMEKSDEFICLLEQEC 200
Query: 101 DQ------KRIRAMKKANKERELKCQHM-QELTKRKQEMVALRLEHQRLSAKLKDYYIFN 153
++ + I++ ++ +E+E + + +ELTK K + + E QRL+A+L +
Sbjct: 201 ERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLT---LQR 257
Query: 154 KYLEKVVENSEESRW------AHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVA 207
+ ++++ N++E+ A +Q K T L ++ T Q + ++T
Sbjct: 258 QKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNED 317
Query: 208 LEDTHKQ--LDMIQQFIQDRSDIWAEVKKKEQQ 238
++ Q L + + I + + ++K E++
Sbjct: 318 SQNRQLQQKLAALSRQIDELEETNRSLRKAEEE 350
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 39.7 bits (91), Expect = 0.002
Identities = 42/199 (21%), Positives = 85/199 (42%), Gaps = 6/199 (3%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELG 80
E + ++ L + SE + K + ++ + + + +RR+ L + E+L
Sbjct: 797 EEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLK 856
Query: 81 VKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQ 140
EA+ K ++K E I++ ++ + A K+ + + EL + + E +
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQK 916
Query: 141 RLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLLGTI----KMATLNLFQIV 196
+LS KLK+ + L ++ E RW H+ T K + I + +TL L +
Sbjct: 917 QLSEKLKEESEQKEQLRRLKNEMENERW-HLGKTIEKLQKEMADIVEASRTSTLELQNQL 975
Query: 197 SKHLKEVTEVALEDTHKQL 215
++ KE L + +QL
Sbjct: 976 DEY-KEKNRRELAEMQRQL 993
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 39.7 bits (91), Expect = 0.002
Identities = 54/244 (22%), Positives = 102/244 (41%), Gaps = 63/244 (25%)
Query: 44 LLEKKKETEIMHQTMVQKKKM-------FQRRMETLNLRWEELGVKEAQLKAHIQ----- 91
LLEKK++ E + QT+ +K + +M LN LGV+ LK +
Sbjct: 882 LLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRA 941
Query: 92 ---KSEQFIQEND-----------------------QKRIRAMKKANKERELKCQH---- 121
K EQ ++N+ Q +KK N++R+ K Q
Sbjct: 942 EEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALIN 1001
Query: 122 ----MQELTKRKQEMVALRLEHQR---LS----AKLKDYYIFNKYLEKVVENSEESRWAH 170
+Q +++ ++E+ L+ E ++ LS ++++ +Y EK V + + +
Sbjct: 1002 RKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY 1061
Query: 171 IQNTAAKKTLLLGTI------KMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQD 224
++ T ++K + L I K+A FQ + K + + L+D Q+D++Q I +
Sbjct: 1062 LKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQ----TLQDKTNQIDLLQAEISE 1117
Query: 225 RSDI 228
I
Sbjct: 1118 NQAI 1121
Score = 33.9 bits (76), Expect = 0.13
Identities = 29/157 (18%), Positives = 73/157 (46%), Gaps = 8/157 (5%)
Query: 28 QKLPNVEGASESPSIWLLEKKKETEIMHQTM---VQKKKMFQRRMETLNLRWEELGVKEA 84
+K+ +E ++ E +K+ EI + + V+ +K Q + + + ++ + A
Sbjct: 2033 EKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAA 2092
Query: 85 QLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQ-----HMQELTKRKQEMVALRLEH 139
++ A K ++ +Q N + MK+ +++ E + + H++E ++++ ALR E
Sbjct: 2093 RVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREK 2152
Query: 140 QRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAA 176
L + + + +K V+ +E+ + + AA
Sbjct: 2153 VHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAA 2189
Score = 33.1 bits (74), Expect = 0.22
Identities = 52/268 (19%), Positives = 115/268 (42%), Gaps = 39/268 (14%)
Query: 5 IMEEEDLAEYFRLQ-------YGERLLQM------LQKLPNVEGASESPSIWLLEKKKET 51
I+E+EDL + Q + ER+ Q+ +++ P G + K +
Sbjct: 1429 IIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAA 1488
Query: 52 EIMHQTMVQKKKMFQRRME----TLNLRWEELGVKEAQLKAHIQKSEQ------FIQEND 101
I + +++ K Q + T+ + L E+Q+ A ++ + +QE
Sbjct: 1489 LISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEER 1548
Query: 102 QKRIRAMKKA---NKERELKCQHM----QELTKRKQEMVALRLEHQRLS--AKLKDYYIF 152
K I M ++ N+ C+ + + LT+ K+++V +E + S A+ ++
Sbjct: 1549 DKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVK-EIESLKSSKIAESTEWQEK 1607
Query: 153 NKYLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTH 212
+K L+K E +S + ++ N A + ++ ++ L+ + TE ++T
Sbjct: 1608 HKELQKEYEILLQS-YENVSNEAERIQHVVEAVRQEKQELYGKLRS-----TEANKKETE 1661
Query: 213 KQLDMIQQFIQDRSDIWAEVKKKEQQRV 240
KQL +Q +++ + + K +QQ++
Sbjct: 1662 KQLQEAEQEMEEMKEKMRKFAKSKQQKI 1689
Score = 31.6 bits (70), Expect = 0.65
Identities = 33/167 (19%), Positives = 71/167 (42%), Gaps = 5/167 (2%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELG 80
E LLQ + + N + + ++K+E ++ KK +++++ EE+
Sbjct: 1616 EILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMK 1675
Query: 81 VKEAQL-KAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEH 139
K + K+ QK + +END+ R + +E + K+E+ +++E+
Sbjct: 1676 EKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEY 1735
Query: 140 QRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLLGTIK 186
+ LS K + L + V++ + I+ +K+ L T K
Sbjct: 1736 ETLSKKFQSLMSEKDSLSEEVQDLKH----QIEGNVSKQANLEATEK 1778
Score = 29.3 bits (64), Expect = 3.2
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Query: 46 EKKKETEIM---HQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQ 102
E +KE EI+ ++ + + + Q +E + +EL K +A+ +++E+ +QE +Q
Sbjct: 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQ 1669
Query: 103 KRIRAMKKANKERELKCQHMQELTKRKQEMVA 134
+ +K K + K Q + EL + + A
Sbjct: 1670 EMEEMKEKMRKFAKSKQQKILELEEENDRLRA 1701
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 39.7 bits (91), Expect = 0.002
Identities = 42/165 (25%), Positives = 75/165 (45%), Gaps = 15/165 (9%)
Query: 85 QLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSA 144
QL+ Q+ EQ QE + R A K+ EL + +QE ++ K+E+ A+RL H++
Sbjct: 404 QLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVL 463
Query: 145 KLKDYYIFN-KYLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIV------- 196
++ Y + L + + EE I+ A +T L T++ L V
Sbjct: 464 GVRARYERELRELHEDKKRQEEELRGQIREEKA-RTRELETLQQTVEELQAQVHSMDGAK 522
Query: 197 ---SKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQ 238
+ LKE E + +Q + ++Q + + AE+K KE++
Sbjct: 523 GWFERRLKEAEESLQQQQQEQEEALKQCREQHA---AELKGKEEE 564
Score = 35.8 bits (81), Expect = 0.034
Identities = 40/195 (20%), Positives = 84/195 (43%), Gaps = 50/195 (25%)
Query: 44 LLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVK-------EAQLKAHIQKSEQF 96
L E KK E + ++++K R +ETL EEL + + + ++++E+
Sbjct: 476 LHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEES 535
Query: 97 IQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYL 156
+Q+ Q++ A+K+ + QH EL +++E+ +R +
Sbjct: 536 LQQQQQEQEEALKQCRE------QHAAELKGKEEELQDVRDQ------------------ 571
Query: 157 EKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQL- 215
+E ++E R H++ ++ K + T+ + L++ AL+D +QL
Sbjct: 572 ---LEQAQEERDCHLKTISSLKQEVKDTVDGQRI---------LEKKGSAALKDLKRQLH 619
Query: 216 ------DMIQQFIQD 224
D +Q+ +QD
Sbjct: 620 LERKRADKLQERLQD 634
>gi|41349446 stromal interaction molecule 2 [Homo sapiens]
Length = 833
Score = 39.3 bits (90), Expect = 0.003
Identities = 47/216 (21%), Positives = 95/216 (43%), Gaps = 21/216 (9%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEEL- 79
E + +M++ L +++ A +S +K E V+K+ + ++ M+ +N EE
Sbjct: 330 EHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEAC 389
Query: 80 GVKEAQLKAHIQKSEQFIQENDQKRIR-AMKKANKERELKCQHMQELTKRKQEMVALRLE 138
++E + A + S + E + +++R A+KKA KE EL+ +K + +E
Sbjct: 390 RLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVE 449
Query: 139 HQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSK 198
Q + K + N ++ + E + K++ + GT+ +A S
Sbjct: 450 VQYYNIKRQ-----NAEMQLAIAKDE------AEKIKKKRSTVFGTLHVAH-------SS 491
Query: 199 HLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKK 234
L EV LE K L + +++R W +++K
Sbjct: 492 SLDEVDHKILE-AKKALSELTTCLRERLFRWQQIEK 526
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 39.3 bits (90), Expect = 0.003
Identities = 54/258 (20%), Positives = 112/258 (43%), Gaps = 38/258 (14%)
Query: 11 LAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRME 70
+A++ + G+ +Q Q L NV + L EK+ +I+ Q + + R+ E
Sbjct: 1812 VAQHVEKEGGKNNIQAKQNLENVFDDVQKT---LQEKELTCQILEQKIKELDSCLVRQKE 1868
Query: 71 TLNLRWEELGVKEAQLKAHIQ-----KSEQFIQENDQKRIRA------------------ 107
+ EEL K +L+A Q K + ++EN +++ ++
Sbjct: 1869 VHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDL 1928
Query: 108 -MKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEES 166
K A ERE K + +E+ + ++++ LR EHQ+ LK Y + EK+ + E+
Sbjct: 1929 EFKLAGAERE-KQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQERE-EKIKQEQEDL 1986
Query: 167 RWAHIQNTAAKKTLLLGTIKMA------TLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQ 220
H N+ K+ + ++A + + + ++K +EV LE ++ + + +
Sbjct: 1987 ELKH--NSTLKQLMREFNTQLAQKEQELEMTIKETINK-AQEVEAELLESHQEETNQLLK 2043
Query: 221 FIQDRSDIWAEVKKKEQQ 238
I ++ D K+ ++
Sbjct: 2044 KIAEKDDDLKRTAKRYEE 2061
Score = 38.5 bits (88), Expect = 0.005
Identities = 48/227 (21%), Positives = 108/227 (47%), Gaps = 19/227 (8%)
Query: 19 YGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEE 78
Y E+L Q+ QKL ++E + I L ++ E E + + + + +++ L + E+
Sbjct: 817 YEEQLAQLQQKLLDLE----TERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 872
Query: 79 LGVK-EAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRL 137
+ E ++K+ Q E +++ ++++ + K+ E+E M+E K++ E++
Sbjct: 873 QNSEMEQKVKSLTQVYESKLEDGNKEQEQT-KQILVEKENMILQMREGQKKEIEILT--- 928
Query: 138 EHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVS 197
Q+LSAK +I N+ E +N E+ ++ K + T+K L+ +
Sbjct: 929 --QKLSAKEDSIHILNEEYETKFKNQEKK----MEKVKQKAKEMQETLKKKLLDQEAKLK 982
Query: 198 KHLK----EVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRV 240
K L+ E+++ + K L+M Q SD + ++ +++++
Sbjct: 983 KELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQI 1029
Score = 37.0 bits (84), Expect = 0.015
Identities = 48/240 (20%), Positives = 103/240 (42%), Gaps = 33/240 (13%)
Query: 21 ERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMF----QRRM-ETLNLR 75
E+L + LQ+L ++ + L+ + ++ + + + + Q K M +R+M ETL ++
Sbjct: 321 EQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK 380
Query: 76 WEELG----------VKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQEL 125
EE+ + +L+ +KSE+ E +K + +K + R M E
Sbjct: 381 EEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 440
Query: 126 TK-----RKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTL 180
K ++E ++L+ E R+ ++ D V++ S E + A +Q K+
Sbjct: 441 IKTIEKTSEEERISLQQELSRVKQEVVD----------VMKKSSEEQIAKLQKLHEKE-- 488
Query: 181 LLGTIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAEVKKKEQQRV 240
L + Q + +E +VALE + + I Q + + + E + +++ +
Sbjct: 489 -LARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAI 547
Score = 33.5 bits (75), Expect = 0.17
Identities = 48/188 (25%), Positives = 79/188 (42%), Gaps = 42/188 (22%)
Query: 28 QKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLK 87
QK +E +E L ++ +I H+ +VQK + FQ E + R VKEA+ K
Sbjct: 1536 QKTIEIESLNEV----LKNYNQQKDIEHKELVQKLQHFQELGEEKDNR-----VKEAEEK 1586
Query: 88 AHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLK 147
EN ++A EL +K+E LEH LS K K
Sbjct: 1587 I-------LTLENQVYSMKA----------------ELETKKKE-----LEHVNLSVKSK 1618
Query: 148 DYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVA 207
+ + K LE +E+ ++ A ++ A +K + IK L+ + + K+ TE
Sbjct: 1619 EEEL--KALEDRLESESAAKLAELKRKAEQK---IAAIKKQLLSQMEEKEEQYKKGTESH 1673
Query: 208 LEDTHKQL 215
L + + +L
Sbjct: 1674 LSELNTKL 1681
Score = 32.7 bits (73), Expect = 0.29
Identities = 48/228 (21%), Positives = 99/228 (43%), Gaps = 48/228 (21%)
Query: 9 EDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRR 68
E +E R+ + L ++ Q++ +V S I L+K E E + +K++ ++
Sbjct: 445 EKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKE-----LARKEQELTKK 499
Query: 69 METLNLRWEELGVKEAQLKAHIQKSE----QFIQENDQKRIRAMKKANKERELKCQHMQE 124
++T ++E Q+K ++KS+ + QE +Q+ A++ EL+ Q
Sbjct: 500 LQTREREFQE------QMKVALEKSQSEYLKISQEKEQQESLALE------ELELQKKAI 547
Query: 125 LTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEK-VVENSEESRWAHIQNTAAKKTLLLG 183
LT+ + ++ L+ E + ++ + LEK + EN +S+ + A K
Sbjct: 548 LTESENKLRDLQQEAETYRTRILE---LESSLEKSLQENKNQSKDLAVHLEAEK------ 598
Query: 184 TIKMATLNLFQIVSKHLKEVTEVALEDTHKQLDMIQQFIQDRSDIWAE 231
+KH KE+T V +E +L+ ++ + +W E
Sbjct: 599 -------------NKHNKEIT-VMVEKHKTELESLK---HQQDALWTE 629
Score = 31.2 bits (69), Expect = 0.85
Identities = 57/278 (20%), Positives = 120/278 (43%), Gaps = 58/278 (20%)
Query: 7 EEEDLAEYFRLQYGER---LLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKK 63
+ E+L E +Q E+ + ++ QK+ E + + K+E T+ + ++
Sbjct: 1054 QAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQE 1113
Query: 64 MFQRRMETLNLRWEELGVKEAQLKAHIQKSE----QFIQEND--QKRIRAMKKANKEREL 117
+++ +N L E +LKAH++K E + ++EN Q+++ +K +E +
Sbjct: 1114 QLKQKSAHVN----SLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKR 1169
Query: 118 KCQHM-QELTKRKQEMVALRLEHQRLSAKLKDYYI-FNKYLEKVV--------------- 160
K + +L +E +L+ H++ + L+D + F K E++
Sbjct: 1170 KVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLE 1229
Query: 161 -------------ENSEESRWAHIQN--TAAKKTLLLGTIKMATLNLFQIVSKHLKEVTE 205
N+ SR +H Q+ T K+ LL+ T ++ L L+++TE
Sbjct: 1230 AKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSEL------EAQLRQLTE 1283
Query: 206 ------VALEDTHKQLDMIQQFIQD-RSDIWAEVKKKE 236
++ + QL+ + I+ ++DI + V +KE
Sbjct: 1284 EQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKE 1321
Score = 29.3 bits (64), Expect = 3.2
Identities = 48/268 (17%), Positives = 116/268 (43%), Gaps = 51/268 (19%)
Query: 16 RLQYGERLLQMLQKLPNVEGASE------------SPSIWLLEKKKETEIMHQTMVQKKK 63
RL+ G + +L+ LP +E +E P + K E + Q + +++
Sbjct: 234 RLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQEN 293
Query: 64 MFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQ-KRIRAMKKANKERELK-CQH 121
+ +R ET+ E+ + ++ +A ++ ++ +QE ++ K + +K +L+ ++
Sbjct: 294 LLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKN 353
Query: 122 MQELTKRKQEMVALRLEHQ-------------RLSAKLKDYYIFNKYLEKVVENSEESRW 168
+ E ++ + MV + Q +L +++K + L + E SE + +
Sbjct: 354 LIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAF 413
Query: 169 AHIQN--TAAKKT----------------LLLGTIKMATLNLFQIVSKHLKEVTEVALED 210
++ + A+KT + T + ++L Q +S+ +EV +V +
Sbjct: 414 EELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKS 473
Query: 211 THKQLDMIQQFIQDRSDIWAEVKKKEQQ 238
+ +Q+ +Q+ + E+ +KEQ+
Sbjct: 474 SEEQIAKLQKLHE------KELARKEQE 495
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 39.3 bits (90), Expect = 0.003
Identities = 40/144 (27%), Positives = 72/144 (50%), Gaps = 14/144 (9%)
Query: 22 RLLQMLQKLPNVEGASESP---SIWLLEKKKETEIMHQTMVQK---KKMFQRRMETLNLR 75
+LL+ LQK A E+ +I E+K++ + + M Q+ K++ Q RME LR
Sbjct: 902 KLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEK-ELR 960
Query: 76 WEEL-----GVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQ 130
+++ KE A + ++E+ I+E + +R +A+ ++ERE + QHM + +
Sbjct: 961 AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHM--MLMKAM 1018
Query: 131 EMVALRLEHQRLSAKLKDYYIFNK 154
E E +RL + +D NK
Sbjct: 1019 EARKKAEEKERLKQEKRDEKRLNK 1042
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 39.3 bits (90), Expect = 0.003
Identities = 61/250 (24%), Positives = 110/250 (44%), Gaps = 33/250 (13%)
Query: 12 AEYFRLQYGERLLQMLQKLPNVEGAS-ESPSIWLLEKKKETEIMHQTMVQK-KKMFQRRM 69
AE +L +R + L KL E A ES + L E ++ Q V + ++ F+ +
Sbjct: 329 AEQEQLSLSQRQAKEL-KLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQ 387
Query: 70 ETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKAN----KERELKCQHMQEL 125
E L +E+ A+LK ++E+ + ++ ++++ + KE E +H++E
Sbjct: 388 EQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEES 447
Query: 126 TKRKQEMVALRLEHQRLS----------AKLKDYYIFNKYLEKVVENS---EESRWAHIQ 172
K QE V RLE RLS A L + + L K + E+ R AH++
Sbjct: 448 EKAMQERVQ-RLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLE 506
Query: 173 NTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTEVAL--EDTHKQLDMIQQFIQDRSDIWA 230
+ + A L Q+V++ V+++ L E ++L+ +QQ
Sbjct: 507 DKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQ---------- 556
Query: 231 EVKKKEQQRV 240
E+ K+Q+RV
Sbjct: 557 ELSLKDQERV 566
Score = 28.5 bits (62), Expect = 5.5
Identities = 37/168 (22%), Positives = 71/168 (42%), Gaps = 22/168 (13%)
Query: 26 MLQKLPNVEGASESPSIWLLEKKKETEIMHQTMV----QKKKMFQRRMETLNLRWEELGV 81
+L+ + G S+ E + T ++ + + +K K F MET++ + EE+
Sbjct: 216 VLRAVEQAMGHSQDRLTTFQENQARTHVLSKEVQHLREEKSKQFLDLMETIDKQREEMAK 275
Query: 82 KEAQLKAHIQKSEQFIQEND------QKRIRAMKKANKERELKCQHMQE-LTKRKQEMVA 134
A + + ++ + E + +++ + A E K Q + E L +QE ++
Sbjct: 276 SSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLS 335
Query: 135 LRLEHQRLSAKLKDYYIFNKYLEKVVENSEESRWAHIQNTAAKKTLLL 182
L QR + +LK LE+ ES+ + A +K LLL
Sbjct: 336 L---SQRQAKELK--------LEQQEAAERESKLLRDLSAANEKNLLL 372
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 39.3 bits (90), Expect = 0.003
Identities = 38/158 (24%), Positives = 75/158 (47%), Gaps = 11/158 (6%)
Query: 7 EEEDLAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQ 66
EE + E + E+L ++ +KL +E I E++KE E + ++++ +
Sbjct: 469 EERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQERE 528
Query: 67 RRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELT 126
+ E R +E KE +L+ +K + +E Q++ + +++ KE+E + Q M+E
Sbjct: 529 KEREKDRERQQE---KEKELEKEQEKQREMEKERKQEKEKELER-QKEKEKELQKMKEQE 584
Query: 127 KRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSE 164
K + L E ++L K++ LE +VE E
Sbjct: 585 KECE----LEKEREKLEEKIEPR---EPNLEPMVEKQE 615
Score = 30.8 bits (68), Expect = 1.1
Identities = 33/157 (21%), Positives = 71/157 (45%), Gaps = 25/157 (15%)
Query: 31 PNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQ--RRMET---------LNLRWEEL 79
P+ + ++ IW +++++EI +K+ + RRME L E+L
Sbjct: 433 PSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKL 492
Query: 80 GV----------KEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRK 129
G+ +E + + ++ ++ +E +Q+R K+ K+RE + + +EL K +
Sbjct: 493 GILEKQPSPEEIREREREKEREREKELEKEQEQER---EKEREKDRERQQEKEKELEKEQ 549
Query: 130 QEMVALRLEH-QRLSAKLKDYYIFNKYLEKVVENSEE 165
++ + E Q +L+ K L+K+ E +E
Sbjct: 550 EKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,926,012
Number of Sequences: 37866
Number of extensions: 323328
Number of successful extensions: 3153
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 439
Number of HSP's that attempted gapping in prelim test: 2295
Number of HSP's gapped (non-prelim): 1217
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.