Search of human proteins with 226528146

Search of human proteins with 226528146

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226528146 HRAS-like suppressor family, member 5 isoform 3
[Homo sapiens]
         (253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226528146 HRAS-like suppressor family, member 5 isoform 3 [Ho...   520   e-148
gi|16905367 HRAS-like suppressor family, member 5 isoform 1 [Hom...   475   e-134
gi|226491950 HRAS-like suppressor family, member 5 isoform 2 [Ho...   448   e-126
gi|149588791 retinoic acid receptor responder (tazarotene induce...   123   1e-28
gi|8923526 HRAS-like suppressor 2 [Homo sapiens]                      108   6e-24
gi|189571621 HRAS-like suppressor 3 [Homo sapiens]                    108   6e-24
gi|189571618 HRAS-like suppressor 3 [Homo sapiens]                    108   6e-24
gi|9966859 HRAS-like suppressor [Homo sapiens]                         99   3e-21
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       43   3e-04
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       43   3e-04
gi|46249410 lecithin retinol acyltransferase [Homo sapiens]            38   0.007
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    36   0.037
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s...    36   0.037
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         35   0.048
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]              35   0.082
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso...    34   0.14 
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso...    34   0.14 
gi|55741677 SET domain containing 1A [Homo sapiens]                    34   0.14 
gi|28557798 family with sequence similarity 84, member B [Homo s...    34   0.14 
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    33   0.18 
gi|7662302 TBK1 binding protein 1 [Homo sapiens]                       33   0.18 
gi|157785645 SPEG complex locus [Homo sapiens]                         33   0.18 
gi|122891864 zinc finger protein, subfamily 1A, 4 [Homo sapiens]       33   0.18 
gi|109715854 calcium-regulated heat-stable protein 1 [Homo sapiens]    33   0.18 
gi|109715858 calcium-regulated heat-stable protein 1 [Homo sapiens]    33   0.18 
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    33   0.24 
gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo ...    33   0.24 
gi|13375646 leucine rich repeat and fibronectin type III domain ...    33   0.24 
gi|33457316 pleckstrin homology domain containing, family O memb...    33   0.24 
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    33   0.31 

>gi|226528146 HRAS-like suppressor family, member 5 isoform 3 [Homo
           sapiens]
          Length = 253

 Score =  520 bits (1338), Expect = e-148
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELE 60
           MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELE
Sbjct: 1   MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELE 60

Query: 61  ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI 120
           ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI
Sbjct: 61  ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI 120

Query: 121 KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV 180
           KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV
Sbjct: 121 KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV 180

Query: 181 KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCRARPDGR 240
           KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCRARPDGR
Sbjct: 181 KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCRARPDGR 240

Query: 241 SEGCWSSYFSCSG 253
           SEGCWSSYFSCSG
Sbjct: 241 SEGCWSSYFSCSG 253


>gi|16905367 HRAS-like suppressor family, member 5 isoform 1 [Homo
           sapiens]
          Length = 279

 Score =  475 bits (1222), Expect = e-134
 Identities = 235/243 (96%), Positives = 236/243 (97%)

Query: 1   MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELE 60
           MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELE
Sbjct: 1   MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELE 60

Query: 61  ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI 120
           ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI
Sbjct: 61  ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI 120

Query: 121 KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV 180
           KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV
Sbjct: 121 KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV 180

Query: 181 KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCRARPDGR 240
           KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC    +G 
Sbjct: 181 KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGL 240

Query: 241 SEG 243
             G
Sbjct: 241 RYG 243


>gi|226491950 HRAS-like suppressor family, member 5 isoform 2 [Homo
           sapiens]
          Length = 269

 Score =  448 bits (1153), Expect = e-126
 Identities = 225/243 (92%), Positives = 226/243 (93%), Gaps = 10/243 (4%)

Query: 1   MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELE 60
           MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHS          E
Sbjct: 1   MGLSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHS----------E 50

Query: 61  ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI 120
           ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI
Sbjct: 51  ESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLI 110

Query: 121 KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV 180
           KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV
Sbjct: 111 KQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVV 170

Query: 181 KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCRARPDGR 240
           KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC    +G 
Sbjct: 171 KYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGL 230

Query: 241 SEG 243
             G
Sbjct: 231 RYG 233


>gi|149588791 retinoic acid receptor responder (tazarotene induced)
           3 [Homo sapiens]
          Length = 164

 Score =  123 bits (309), Expect = 1e-28
 Identities = 59/106 (55%), Positives = 76/106 (71%), Gaps = 2/106 (1%)

Query: 130 PRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGS--ITSIFSNRAVVKYSRLED 187
           P+PGDLIEIFR+GYEHWA+Y+ D  V+HLAPPSE    GS  + S+ SN A VK  RLED
Sbjct: 8   PKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEVKRERLED 67

Query: 188 VLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233
           V+ GC ++VNN LD  Y P PV+ II   K+MV + ++YS++  NC
Sbjct: 68  VVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNC 113


>gi|8923526 HRAS-like suppressor 2 [Homo sapiens]
          Length = 162

 Score =  108 bits (269), Expect = 6e-24
 Identities = 57/112 (50%), Positives = 73/112 (65%), Gaps = 2/112 (1%)

Query: 124 AEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRAVVK 181
           A  +PRPR GDLIEI R GY HWAIYV D  VVHLAP SE    G  S+ S  +N+A+VK
Sbjct: 2   ALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVK 61

Query: 182 YSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233
              L  V  G +++VNNK D  Y PLP +KI++R +++V + + YSL   NC
Sbjct: 62  KELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNC 113


>gi|189571621 HRAS-like suppressor 3 [Homo sapiens]
          Length = 162

 Score =  108 bits (269), Expect = 6e-24
 Identities = 57/108 (52%), Positives = 69/108 (63%), Gaps = 2/108 (1%)

Query: 128 PRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRAVVKYSRL 185
           P P+PGDLIEIFR  Y HWAIYV D  VVHLAPPSE    G  S+ S  +++A+VK   L
Sbjct: 6   PEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELL 65

Query: 186 EDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233
            DV     ++VNNK D  Y PLP  KIIQR +++V + V Y L   NC
Sbjct: 66  YDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENC 113


>gi|189571618 HRAS-like suppressor 3 [Homo sapiens]
          Length = 162

 Score =  108 bits (269), Expect = 6e-24
 Identities = 57/108 (52%), Positives = 69/108 (63%), Gaps = 2/108 (1%)

Query: 128 PRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRAVVKYSRL 185
           P P+PGDLIEIFR  Y HWAIYV D  VVHLAPPSE    G  S+ S  +++A+VK   L
Sbjct: 6   PEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELL 65

Query: 186 EDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233
            DV     ++VNNK D  Y PLP  KIIQR +++V + V Y L   NC
Sbjct: 66  YDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENC 113


>gi|9966859 HRAS-like suppressor [Homo sapiens]
          Length = 168

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 47/105 (44%), Positives = 74/105 (70%), Gaps = 1/105 (0%)

Query: 130 PRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSE-EFEVGSITSIFSNRAVVKYSRLEDV 188
           P PGDLIE+FR GY+HWA+Y+ D  V+++AP         S  S+FS++A+VK   L+DV
Sbjct: 15  PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKSVFSSKALVKMQLLKDV 74

Query: 189 LHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233
           +   ++++NNK D TY PLPV++II+R++ ++ + V Y+L+  NC
Sbjct: 75  VGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNC 119


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 14/122 (11%)

Query: 11  YALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQ 70
           +ALR  R  PP P P   ++ +GP  +PP L  S  P  G        L E  G +    
Sbjct: 777 FALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPG 836

Query: 71  LPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPRP 130
            PA   P    E+     +G        T PS+ +    +P  E     IKQ      RP
Sbjct: 837 PPAPAGPASDTEEEEPGPEG--------TPPSRGSSGEGLPFAEEGNLTIKQ------RP 882

Query: 131 RP 132
           +P
Sbjct: 883 KP 884



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 21/53 (39%), Positives = 25/53 (47%)

Query: 12  ALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVG 64
           A RLP  P PL    SRT     ++ P  L  S +P  GL+  SP     SVG
Sbjct: 271 AARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVG 323


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 14/122 (11%)

Query: 11  YALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQ 70
           +ALR  R  PP P P   ++ +GP  +PP L  S  P  G        L E  G +    
Sbjct: 859 FALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPG 918

Query: 71  LPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPRP 130
            PA   P    E+     +G        T PS+ +    +P  E     IKQ      RP
Sbjct: 919 PPAPAGPASDTEEEEPGPEG--------TPPSRGSSGEGLPFAEEGNLTIKQ------RP 964

Query: 131 RP 132
           +P
Sbjct: 965 KP 966



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 21/53 (39%), Positives = 25/53 (47%)

Query: 12  ALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVG 64
           A RLP  P PL    SRT     ++ P  L  S +P  GL+  SP     SVG
Sbjct: 353 AARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVG 405


>gi|46249410 lecithin retinol acyltransferase [Homo sapiens]
          Length = 230

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 13/114 (11%)

Query: 133 GDLIEIFRIGYEHWAIYVEDDCVVHLAPP---SEEFEVGSITSIFSNR----------AV 179
           GD++E+ R    H+ IY+ D+ V H+ P    +   ++G    + SN+          A 
Sbjct: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107

Query: 180 VKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233
           ++   +ED  +G +  VN+  +       +++ + R  + +     YSL+  NC
Sbjct: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNC 161


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 35.8 bits (81), Expect = 0.037
 Identities = 38/114 (33%), Positives = 42/114 (36%), Gaps = 14/114 (12%)

Query: 4   SPGAEGEYALRLPRIP--PPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEE 61
           SP   G  A   PR P  P  PKP    A   P+  PP  R+ A P  G  S SPL    
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLATPS 308

Query: 62  SVGFA---------ALVQLPAKQPPPGTLEQGRSI-QQGEKAVVSLETTPSQKA 105
             G           A   LPA  PP   L     +      A  SL+T PS  A
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362


>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
           sapiens]
          Length = 486

 Score = 35.8 bits (81), Expect = 0.037
 Identities = 37/135 (27%), Positives = 55/135 (40%), Gaps = 26/135 (19%)

Query: 12  ALRLPRIPPPLPKPASRTA----GTGPKDQPPALRRS---AVPHSGLNSISPLELEESVG 64
           A+  P +P PLPK  S  A    GT P  +   +R S    VP   +    P + EE   
Sbjct: 284 AMEEPAVPAPLPKKISSEAWPPVGTPPSSESEPVRTSREHPVPLLPIRQTLPEDNEEPPA 343

Query: 65  FAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLIKQAA 124
                       PP TLE    +Q  E+ V   E  P  + +    P+PEN+ + +++  
Sbjct: 344 L-----------PPRTLE---GLQVEEEPVYEAEPEPEPEPE----PEPENDYEDVEEMD 385

Query: 125 EGKPRPRP-GDLIEI 138
             +    P GD  E+
Sbjct: 386 RHEQEDEPEGDYEEV 400


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 35.4 bits (80), Expect = 0.048
 Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 10/96 (10%)

Query: 19  PPPLPKPASRTAGTGPKDQPPA------LRRSAVPHSGLNSI----SPLELEESVGFAAL 68
           PPPLP   +  A  GP  QPP       L     P  G  ++    +P  L  S+  AA 
Sbjct: 269 PPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAA 328

Query: 69  VQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQK 104
                  PPP TL+  R   Q   A  S    PSQ+
Sbjct: 329 KAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQR 364



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 32/96 (33%), Positives = 39/96 (40%), Gaps = 11/96 (11%)

Query: 16  PRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQ 75
           PR P P+P+P S      P+   P L  S +   GL +  P     S G   L+   A  
Sbjct: 389 PRAPAPVPQPFSL-----PEPSQPIL-PSVLSLLGLPTPGP---SHSDGSFNLLGSDAHL 439

Query: 76  PPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIP 111
           PPP TL  G   Q       SL  T S     SS+P
Sbjct: 440 PPPPTLSSGSPPQPRHPIQPSLPGTTS--GSLSSVP 473



 Score = 28.1 bits (61), Expect = 7.7
 Identities = 41/145 (28%), Positives = 53/145 (36%), Gaps = 29/145 (20%)

Query: 3   LSPGA-EGEYALRLPRIPPP----LPKPASR----------------TAGTGPKDQPPAL 41
           L+PG  EG   L    +PPP    LP P++                 TAG G      A 
Sbjct: 587 LAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAG 646

Query: 42  RRSAVPHSGLNSISPLELEESVGFAALVQLPAK------QPPPGTLEQGRSIQQGEKA-V 94
             S  P SGL  +SPL          L+ L +        PP GT  Q   +   +    
Sbjct: 647 GPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPP 706

Query: 95  VSLETTPSQKADWSSIPK-PENEGK 118
            S  TT +     SS+ K P N G+
Sbjct: 707 TSSVTTATTDPGASSLGKAPSNSGR 731


>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
          Length = 1543

 Score = 34.7 bits (78), Expect = 0.082
 Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 6/59 (10%)

Query: 4    SPGAEGEYALRLPRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEES 62
            S G  G    +LP  PPP     S+ +GTGP  QP A    ++ H+   S SPL  + S
Sbjct: 1015 SKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGA----SLAHTA--SASPLASQSS 1067


>gi|225543215 antigen identified by monoclonal antibody Ki-67 isoform
            2 [Homo sapiens]
          Length = 2896

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 13/89 (14%)

Query: 55   SPLELEESVGFAALVQLPAKQPPPGTLEQGRSIQQGEK------------AVVSLETTPS 102
            +P   EES+      ++P K PPP   +   S ++  K            AV  L  T  
Sbjct: 2208 APGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSG 2267

Query: 103  QKADWSSIPKPENEG-KLIKQAAEGKPRP 130
            Q       P   +EG K++KQ A+ KP P
Sbjct: 2268 QSTHTHKEPASGDEGIKVLKQRAKKKPNP 2296


>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
            1 [Homo sapiens]
          Length = 3256

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 13/89 (14%)

Query: 55   SPLELEESVGFAALVQLPAKQPPPGTLEQGRSIQQGEK------------AVVSLETTPS 102
            +P   EES+      ++P K PPP   +   S ++  K            AV  L  T  
Sbjct: 2568 APGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSG 2627

Query: 103  QKADWSSIPKPENEG-KLIKQAAEGKPRP 130
            Q       P   +EG K++KQ A+ KP P
Sbjct: 2628 QSTHTHKEPASGDEGIKVLKQRAKKKPNP 2656


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 17/67 (25%)

Query: 19   PPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQPPP 78
            P P P+P  R +   P   PP  RR                 ++V F+A+  +PA +PPP
Sbjct: 1141 PAPAPRPDERPSSPIPLLPPPKKRR-----------------KTVSFSAIEVVPAPEPPP 1183

Query: 79   GTLEQGR 85
             T  Q +
Sbjct: 1184 ATPPQAK 1190



 Score = 28.5 bits (62), Expect = 5.9
 Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 2/50 (4%)

Query: 19  PPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPL--ELEESVGFA 66
           PP  P+P     G GP  +   +R S  P S   S SP      ESV FA
Sbjct: 434 PPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFA 483


>gi|28557798 family with sequence similarity 84, member B [Homo
           sapiens]
          Length = 310

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 15/29 (51%), Positives = 21/29 (72%), Gaps = 1/29 (3%)

Query: 131 RPGDLIE-IFRIGYEHWAIYVEDDCVVHL 158
           +PGDL+E + +  Y HWA+YV +  VVHL
Sbjct: 117 KPGDLVEFVSQAQYPHWAVYVGNFQVVHL 145


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)

Query: 14  RLPRIPPPLPKPASRTAGTGPKDQPPALRRS-----AVPHSGLNSISPL---ELEESVGF 65
           RL R PPP P PA+ + G  P   PP    S       P+ GL + +PL    L      
Sbjct: 756 RLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPA-APLAGPALPARRLS 814

Query: 66  AALVQLPAKQP--PPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLIKQA 123
            A   L A QP  P G      S +    +   L  TP+ +A   + P P+        A
Sbjct: 815 RASRPLSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARA---AAPSPDRRDSASPGA 871

Query: 124 AEG 126
           A G
Sbjct: 872 AGG 874


>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
          Length = 615

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 58/211 (27%), Positives = 76/211 (36%), Gaps = 40/211 (18%)

Query: 20  PPLPKPASRTAGTGPK-DQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQPPP 78
           PP P P  R +   P    P   RRS VP S  +              A    P   PPP
Sbjct: 375 PPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPP 434

Query: 79  G--TLE----------------QGRS--IQQGEKAVVSLETTPSQKADWSSIPKPENEGK 118
           G  TL                 QGR    +  E A  +  + P  +A+ +++PKP   G 
Sbjct: 435 GERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGS 494

Query: 119 LIKQAAEGKPRP-RPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSIT------ 171
            +     G  RP  P    E  R+ +E      ED+  V  +PPS   EVG+I       
Sbjct: 495 EL----YGPGRPLSPRRAFEGIRLRFEKQP-SEEDEWAVPTSPPSP--EVGTIRCASFCA 547

Query: 172 --SIFSNRAVVKYSRLEDVLHGCSWKVNNKL 200
              I  + A   Y+  E   H  SW   N L
Sbjct: 548 GFPIPESPAATAYAHAE---HAQSWPSINLL 575


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 3/77 (3%)

Query: 19   PPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQ-PP 77
            P  LP P    A  G   +   LRR +   S L    P EL   +  AA V+LP ++ P 
Sbjct: 1989 PEALPSPGQEPAA-GASPRRGELRRGSSAESALPRAGPRELGRGLHKAASVELPQRRSPS 2047

Query: 78   PGTLEQGR-SIQQGEKA 93
            PG     R  + +GE A
Sbjct: 2048 PGATRLARGGLGEGEYA 2064


>gi|122891864 zinc finger protein, subfamily 1A, 4 [Homo sapiens]
          Length = 585

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 29/96 (30%), Positives = 37/96 (38%), Gaps = 14/96 (14%)

Query: 3   LSPGAEGEYALRLPRIPPPLPKPASRTAGTGPKD-----------QPPALRRSAVPHSGL 51
           L+P     Y    P +P  L  P SR AG GP+D           + P     A P +G 
Sbjct: 395 LTPVISSVYTQMQP-LPGRLELPGSREAGEGPEDLADGGPLLYRPRGPLTDPGASPSNGC 453

Query: 52  NSISPLELEESVGFAALVQLPAKQP--PPGTLEQGR 85
              +  E       A +V LP   P  PP T+  GR
Sbjct: 454 QDSTDTESNHEDRVAGVVSLPQGPPPQPPPTIVVGR 489


>gi|109715854 calcium-regulated heat-stable protein 1 [Homo
          sapiens]
          Length = 147

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 19 PPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQPP 77
          PPP P+P +  A  G  D P +  RS  P  G    SPL    +  F+A V+  A Q P
Sbjct: 5  PPPPPQPPTHQASVGLLDTPRSRERSPSPLRGNVVPSPLPTRRTRTFSATVR--ASQGP 61


>gi|109715858 calcium-regulated heat-stable protein 1 [Homo
          sapiens]
          Length = 147

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 19 PPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQPP 77
          PPP P+P +  A  G  D P +  RS  P  G    SPL    +  F+A V+  A Q P
Sbjct: 5  PPPPPQPPTHQASVGLLDTPRSRERSPSPLRGNVVPSPLPTRRTRTFSATVR--ASQGP 61


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 33/112 (29%), Positives = 41/112 (36%), Gaps = 7/112 (6%)

Query: 4   SPGAEGEYALRLPRIP--PPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEE 61
           SP   G  A   PR P  P  PKP    A   P+  PP  R+ A P  G  S SPL    
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLATPS 308

Query: 62  SVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKP 113
               +A +Q  A    P T        Q    +     +PS      ++P P
Sbjct: 309 P---SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357


>gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo
           sapiens]
          Length = 398

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 38/142 (26%), Positives = 54/142 (38%), Gaps = 25/142 (17%)

Query: 17  RIPPPLPKPASRTAGTGPKDQPPALR--------RSAVPHSGLNSISPLELEESVGFAA- 67
           ++PPPLP   SR     P    P LR        R A+P  G  + S      S   A  
Sbjct: 217 KLPPPLPLCRSRWVLAPPPPVRPRLRVLTPPLALRCALPERGSRTPSTRSAVLSGRVAGL 276

Query: 68  ---LVQLPAKQPPPGTLEQGRSIQQG-EKAVVSLETTPSQKADWSSIPKPENEGKLIKQ- 122
              L   P+ +   G+       Q    +A  S +  P   +   S+P P+ +G+ ++Q 
Sbjct: 277 GTELTLTPSSRRAHGSHALSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQP 336

Query: 123 ------AAEGKPR-----PRPG 133
                  A G PR     PRPG
Sbjct: 337 RLLRAALARGAPRGRTPSPRPG 358


>gi|13375646 leucine rich repeat and fibronectin type III domain
           containing 3 [Homo sapiens]
          Length = 628

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 8/80 (10%)

Query: 8   EGEYALRLPRIPPPLPKPASRTAGTGPKDQPP--------ALRRSAVPHSGLNSISPLEL 59
           E   A+ L   PPP P+ A+ T+   P+D  P        A   + V  +G  +   +++
Sbjct: 374 EATAAVELTVGPPPPPQLANSTSCDPPRDGDPDALTPPSAASASAKVADTGPPTDRGVQV 433

Query: 60  EESVGFAALVQLPAKQPPPG 79
            E    AALVQ P ++P PG
Sbjct: 434 TEHGATAALVQWPDQRPIPG 453


>gi|33457316 pleckstrin homology domain containing, family O member
           2 [Homo sapiens]
          Length = 490

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 11/114 (9%)

Query: 16  PRIPPPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQ 75
           P +PP  P  A  T   G + + P   R+  P S  + +SP E +E     A     ++Q
Sbjct: 202 PLMPPTKPFLAPETTSPGDRVETPVGERAPTPVSASSEVSP-ESQEDSETPAEEDSGSEQ 260

Query: 76  PPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPR 129
           PP   L         +K  VS E    Q+A  +   +P        + +E  PR
Sbjct: 261 PPNSVLP--------DKLKVSWENPSPQEAPAAESAEPSQAP--CSETSEAAPR 304


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 32.7 bits (73), Expect = 0.31
 Identities = 34/116 (29%), Positives = 43/116 (37%), Gaps = 18/116 (15%)

Query: 4   SPGAEGEYALRLPRIP--PPLPKPASRTAGTGPKDQPPALRRSAVPHSGLNSISPLELEE 61
           SP   G  A   PR P  P  PKP    A   P+  PP  R+ A P  G  S SPL    
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLATPS 299

Query: 62  SVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETT----PSQKADWSSIPKP 113
                     P+  P P      +++        S  TT    P+ +A  S +P P
Sbjct: 300 ----------PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,719,333
Number of Sequences: 37866
Number of extensions: 699998
Number of successful extensions: 3384
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 171
Number of HSP's that attempted gapping in prelim test: 3145
Number of HSP's gapped (non-prelim): 384
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.