Search of human proteins with 226443007

Search of human proteins with 226443007

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
         (432 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]        852   0.0  
gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]        798   0.0  
gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]        798   0.0  
gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]        718   0.0  
gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]        647   0.0  
gi|60593095 GRAM domain containing 2 [Homo sapiens]                   140   2e-33
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]        106   5e-23
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]       105   1e-22
gi|144227752 GRAM domain containing 1B [Homo sapiens]                 100   3e-21
gi|187936935 GRAM domain containing 1C [Homo sapiens]                  97   2e-20
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho...    62   8e-10
gi|156231067 TBC1 domain family, member 8 [Homo sapiens]               54   2e-07
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso...    49   1e-05
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso...    49   1e-05
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso...    44   2e-04
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso...    44   2e-04
gi|67763814 death-inducing-protein [Homo sapiens]                      38   0.020
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    36   0.078
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              35   0.17 
gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo ...    33   0.38 
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]    33   0.38 
gi|4557509 cylicin 2 [Homo sapiens]                                    33   0.50 
gi|168229156 NFKB activating protein [Homo sapiens]                    33   0.50 
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    33   0.66 
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    33   0.66 
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]    33   0.66 
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    32   0.86 
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    32   0.86 
gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens]       32   0.86 
gi|39995071 exonuclease 1 isoform b [Homo sapiens]                     32   1.5  

>gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
          Length = 432

 Score =  852 bits (2201), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 1   MTELQQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPD 60
           MTELQQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPD
Sbjct: 1   MTELQQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPD 60

Query: 61  QKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVP 120
           QKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVP
Sbjct: 61  QKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVP 120

Query: 121 TEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTAL 180
           TEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTAL
Sbjct: 121 TEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTAL 180

Query: 181 LVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRP 240
           LVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRP
Sbjct: 181 LVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRP 240

Query: 241 SSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEA 300
           SSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEA
Sbjct: 241 SSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEA 300

Query: 301 KPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIIS 360
           KPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIIS
Sbjct: 301 KPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIIS 360

Query: 361 TFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKI 420
           TFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKI
Sbjct: 361 TFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKI 420

Query: 421 QNNLQKLLENGD 432
           QNNLQKLLENGD
Sbjct: 421 QNNLQKLLENGD 432


>gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
          Length = 416

 Score =  798 bits (2061), Expect = 0.0
 Identities = 404/404 (100%), Positives = 404/404 (100%)

Query: 29  SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 88
           SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE
Sbjct: 13  SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 72

Query: 89  SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 148
           SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN
Sbjct: 73  SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 132

Query: 149 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 208
           WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK
Sbjct: 133 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 192

Query: 209 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 268
           LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY
Sbjct: 193 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 252

Query: 269 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 328
           SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET
Sbjct: 253 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 312

Query: 329 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 388
           VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE
Sbjct: 313 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 372

Query: 389 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 432
           QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 373 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 416


>gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
          Length = 447

 Score =  798 bits (2061), Expect = 0.0
 Identities = 404/404 (100%), Positives = 404/404 (100%)

Query: 29  SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 88
           SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE
Sbjct: 44  SEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTE 103

Query: 89  SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 148
           SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN
Sbjct: 104 SKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSEN 163

Query: 149 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 208
           WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK
Sbjct: 164 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 223

Query: 209 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 268
           LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY
Sbjct: 224 LLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGY 283

Query: 269 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 328
           SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET
Sbjct: 284 SSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSET 343

Query: 329 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 388
           VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE
Sbjct: 344 VGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTE 403

Query: 389 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 432
           QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 404 QAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLLENGD 447


>gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
          Length = 440

 Score =  718 bits (1854), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 69  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 128
           SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS
Sbjct: 77  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQS 136

Query: 129 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 188
           FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII
Sbjct: 137 FTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALII 196

Query: 189 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 248
           ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN
Sbjct: 197 ATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRADRPSSLPLDFN 256

Query: 249 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 308
           DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH
Sbjct: 257 DEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFHATESQTVLNVSKGEAKPTRADAH 316

Query: 309 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 368
           VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI
Sbjct: 317 VNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHHILIFYAIVVCALIISTFYMRYRI 376

Query: 369 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 428
           NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL
Sbjct: 377 NTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEVLCQELTANIVKLEKIQNNLQKLL 436

Query: 429 ENGD 432
           ENGD
Sbjct: 437 ENGD 440


>gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]
          Length = 328

 Score =  647 bits (1669), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 106 YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 165
           YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI
Sbjct: 2   YKANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISI 61

Query: 166 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 225
           PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS
Sbjct: 62  PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTSVGNS 121

Query: 226 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 285
           PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH
Sbjct: 122 PNPSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH 181

Query: 286 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 345
           ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH
Sbjct: 182 ATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHKVKSQKCPMLHH 241

Query: 346 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 405
           ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV
Sbjct: 242 ILIFYAIVVCALIISTFYMRYRINTLEEQLGLLTSIVDTHNTEQAAPSGLRSQVQFNVEV 301

Query: 406 LCQELTANIVKLEKIQNNLQKLLENGD 432
           LCQELTANIVKLEKIQNNLQKLLENGD
Sbjct: 302 LCQELTANIVKLEKIQNNLQKLLENGD 328


>gi|60593095 GRAM domain containing 2 [Homo sapiens]
          Length = 354

 Score =  140 bits (354), Expect = 2e-33
 Identities = 99/281 (35%), Positives = 140/281 (49%), Gaps = 20/281 (7%)

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 166
           K N  +HKLF  VP EE + +  +CALQ++ L QG+L++S NW+CFH+ +FGKD K+ IP
Sbjct: 69  KYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKVVIP 128

Query: 167 AFSVTLIKKTKTALLVPNALIIATVT-DRYIFVSLLSRDSTYKLLKSVCGHLENTSVGN- 224
             SV +IKK K A L+PN L I T T  +YIFVSLLSRDS Y LL+ VC HL+ +S  + 
Sbjct: 129 VVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSKKSL 188

Query: 225 -----SPNPSS-----AENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQ 274
                S  P S      E  +R   PSS  L   D        +     D         +
Sbjct: 189 SVREFSGEPESLEVLIPEMKWRKVCPSSRSLSLPDNIP----CIPPSSVDSTDSFFPSRK 244

Query: 275 TPESENSRDFHATESQTVLNVSKGEAKPTRADAHVNRVPEGKAKSLPVQGLSETVGILHK 334
            P SE SR   A+E+            P       N  P  K        L E      +
Sbjct: 245 PPMSEKSRAQVASENGGRWAWPMPGWGPACPKKMPNCSPTAKNAVYEEDELEEEPRSTGE 304

Query: 335 VKSQKCPMLHHILIFYAIVVCALIISTFYMRYRINTLEEQL 375
           ++       + +L  + +++C L++S+ Y+ +RI+ LE+QL
Sbjct: 305 LRLWD----YRLLKVFFVLICFLVMSSSYLAFRISRLEQQL 341


>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
          Length = 724

 Score =  106 bits (264), Expect = 5e-23
 Identities = 60/164 (36%), Positives = 91/164 (55%), Gaps = 5/164 (3%)

Query: 52  PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSS-----SSSQY 106
           PS     P+   ++   S SS +   +    +     S+N  +  +K  S     S +  
Sbjct: 28  PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYK 87

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIP 166
           + N  F KLF  +P  E L   ++CALQ+EIL QG+L++SENWICF+S +F  +T ISI 
Sbjct: 88  QRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQ 147

Query: 167 AFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 210
              VT +KK KTA L+PNA+ I T ++++ F S  +RD  + L+
Sbjct: 148 LKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 191


>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
          Length = 713

 Score =  105 bits (261), Expect = 1e-22
 Identities = 59/159 (37%), Positives = 89/159 (55%), Gaps = 2/159 (1%)

Query: 52  PSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMH 111
           PS     P+   ++   S SS +   +    +     S+N  +  +  S +  Q   N  
Sbjct: 28  PSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKMLSPTYKQ--RNED 85

Query: 112 FHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVT 171
           F KLF  +P  E L   ++CALQ+EIL QG+L++SENWICF+S +F  +T ISI    VT
Sbjct: 86  FRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVT 145

Query: 172 LIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 210
            +KK KTA L+PNA+ I T ++++ F S  +RD  + L+
Sbjct: 146 CLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLI 184


>gi|144227752 GRAM domain containing 1B [Homo sapiens]
          Length = 738

 Score =  100 bits (248), Expect = 3e-21
 Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 13/173 (7%)

Query: 47  AQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKN---DCKTESKNDPKTERKKSSS- 102
           ++SPTP     + D   ++   S  S D +    ++     C ++S        KKS S 
Sbjct: 28  SRSPTPQ----NQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSW 83

Query: 103 ----SSQYKA-NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVF 157
               S  YK  N  F KLF  +P  E L   ++CALQ++IL QG+L++SENWICF+S +F
Sbjct: 84  YNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIF 143

Query: 158 GKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLL 210
             +T +++    +  + K KTA L+PNA+ + T ++++ F S  +RD TY ++
Sbjct: 144 RWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMM 196


>gi|187936935 GRAM domain containing 1C [Homo sapiens]
          Length = 662

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 1/107 (0%)

Query: 102 SSSQYK-ANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKD 160
           SSS YK  N  + + F  +P  E L   + CALQ++IL QG+L++SENW+CF+S +F  +
Sbjct: 60  SSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWE 119

Query: 161 TKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 207
           T ISI   ++T + K KTA L+PNA+ I T ++++ F S  +RD +Y
Sbjct: 120 TTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166


>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
           sapiens]
          Length = 1266

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 38/125 (30%), Positives = 73/125 (58%), Gaps = 10/125 (8%)

Query: 90  KNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSEN 148
           K D  TE+ K       +A + FH+LF  +P EE L   ++C+  K ++  QG +++S N
Sbjct: 133 KEDDDTEKFK-------EAIVKFHRLF-GMPEEEKLVNYYSCSYWKGKVPRQGWMYLSIN 184

Query: 149 WICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYK 208
            +CF+S + G++ K+ I    +T ++K  T LL+P+ + ++T +  + F   L+ + T+K
Sbjct: 185 HLCFYSFLMGREAKLVIRWVDITQLEKNAT-LLLPDVIKVSTRSSEHFFSVFLNINETFK 243

Query: 209 LLKSV 213
           L++ +
Sbjct: 244 LMEQL 248



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/244 (20%), Positives = 107/244 (43%), Gaps = 33/244 (13%)

Query: 62  KKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPT 121
           +++ ++  +   D      D++  K + K+  K    K    ++ K+  +  +    +P 
Sbjct: 246 EQLANIAMRQLLDNEGFEQDRSLPKLKRKSPKKVSALKRDLDARAKSERY--RALFRLPK 303

Query: 122 EEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 178
           +E L     C L     ++   G++FVS N+ICF SK     + I IP   VT+++K  +
Sbjct: 304 DEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLI-IPLREVTIVEKADS 362

Query: 179 ALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENTSVGNSPNPSSAENSFRA 237
           + ++P+ L I+T     ++F +L  RD    L++ +   L+ T+           +   +
Sbjct: 363 SSVLPSPLSISTRNRMTFLFANLKDRDF---LVQRISDFLQQTT-----------SKIYS 408

Query: 238 DRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYSSSGSQTPESENSRDFH------ATESQT 291
           D+      +F   ++  D  V  R   +   S   S + +++  R F+       T +QT
Sbjct: 409 DK------EFAGSYNSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQT 462

Query: 292 VLNV 295
           ++ +
Sbjct: 463 LMTM 466


>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
          Length = 1140

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 23/196 (11%)

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 163
           +A   F + F  +P +E L     C+L          G++F S+++ICF S+  G   KI
Sbjct: 281 RAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGC-CKI 339

Query: 164 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENTSV 222
            +P   V  I+K +   L+P+ +I++  +   + F+ L  RDS   L++++   L+    
Sbjct: 340 ILPLREVVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDS---LVEALLARLKQVHA 396

Query: 223 GNSPN-PSSAENSFRADRPSSLPLDFNDEFSDLDGVVQQRRQDME--------------G 267
            +  +  +SA++   +    S  +  +  F DL+ +  Q  ++ E               
Sbjct: 397 NHPVHYDTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTA 456

Query: 268 YSSSGSQTPESENSRD 283
           +  SGSQ+P+S  SR+
Sbjct: 457 FQQSGSQSPDSRMSRE 472



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 32/139 (23%), Positives = 66/139 (47%), Gaps = 12/139 (8%)

Query: 76  ASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEPLKQSFTCALQK 135
           A +A + +    E + +P+  R+   +  +++A  +F       P  E L   ++C   K
Sbjct: 120 ALIAEETSSRLAEQEEEPEKFRE---ALVKFEARFNF-------PEAEKLVTYYSCCCWK 169

Query: 136 -EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDR 194
             +  QG L++S N +CF+S   GK+ K+ +P   +  +++T    L  + + I T    
Sbjct: 170 GRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLT-DTIRITTQNKE 228

Query: 195 YIFVSLLSRDSTYKLLKSV 213
             F   L+ D  +K+++ +
Sbjct: 229 RDFSMFLNLDEVFKVMEQL 247


>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 1233

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 36/155 (23%), Positives = 73/155 (47%), Gaps = 13/155 (8%)

Query: 60  DQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSV 119
           D ++ I+ + K    G  +A +  + + +   DP   ++         A +   K F  +
Sbjct: 102 DSEEDITTFVKGKIHGI-IAEENKNLQPQGDEDPGKFKE---------AELKMRKQF-GM 150

Query: 120 PTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 178
           P  E L   ++C+  K  +  QG L+++ N +CF+S + GK+  + +    +T ++K  T
Sbjct: 151 PEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDITRLEKNAT 210

Query: 179 ALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSV 213
            LL P ++ + T      F   L+   T+KL++ +
Sbjct: 211 -LLFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 33/210 (15%)

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKI 163
           +A    ++    +P +E L    +C L     ++   G++F+S N+ICF SK       +
Sbjct: 284 RAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKE-EDACHL 342

Query: 164 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENT-- 220
            IP   VT+++K  ++ ++P+ L I+T +   ++F +L  RD    L++ +   L+ T  
Sbjct: 343 IIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPS 399

Query: 221 ----SVGN----------SPNPSSAENSFRADRPSSLPLDFNDEF------SDLDGVVQ- 259
               S+G+            +P+  E S +   P+S PL     F      +   G+++ 
Sbjct: 400 KQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPAS-PLSSRQSFCAQEAPTASQGLLKL 458

Query: 260 -QRRQDMEGYSSSGSQTPESENSRDFHATE 288
            Q+   ME   + G++    E S   H  E
Sbjct: 459 FQKNSPMEDLGAKGAKEKMKEESWHIHFFE 488


>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1250

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 36/155 (23%), Positives = 73/155 (47%), Gaps = 13/155 (8%)

Query: 60  DQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSV 119
           D ++ I+ + K    G  +A +  + + +   DP   ++         A +   K F  +
Sbjct: 102 DSEEDITTFVKGKIHGI-IAEENKNLQPQGDEDPGKFKE---------AELKMRKQF-GM 150

Query: 120 PTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKT 178
           P  E L   ++C+  K  +  QG L+++ N +CF+S + GK+  + +    +T ++K  T
Sbjct: 151 PEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDITRLEKNAT 210

Query: 179 ALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSV 213
            LL P ++ + T      F   L+   T+KL++ +
Sbjct: 211 -LLFPESIRVDTRDQELFFSMFLNIGETFKLMEQL 244



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 33/210 (15%)

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQ---KEILYQGKLFVSENWICFHSKVFGKDTKI 163
           +A    ++    +P +E L    +C L     ++   G++F+S N+ICF SK       +
Sbjct: 284 RAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKE-EDACHL 342

Query: 164 SIPAFSVTLIKKTKTALLVPNALIIATVTD-RYIFVSLLSRDSTYKLLKSVCGHLENT-- 220
            IP   VT+++K  ++ ++P+ L I+T +   ++F +L  RD    L++ +   L+ T  
Sbjct: 343 IIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDF---LVQRISDFLQKTPS 399

Query: 221 ----SVGN----------SPNPSSAENSFRADRPSSLPLDFNDEF------SDLDGVVQ- 259
               S+G+            +P+  E S +   P+S PL     F      +   G+++ 
Sbjct: 400 KQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPAS-PLSSRQSFCAQEAPTASQGLLKL 458

Query: 260 -QRRQDMEGYSSSGSQTPESENSRDFHATE 288
            Q+   ME   + G++    E S   H  E
Sbjct: 459 FQKNSPMEDLGAKGAKEKMKEESWHIHFFE 488


>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 632

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 3/111 (2%)

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 165
           +A + F K F  +P +E L   ++C+  K  +  QG L++S N++ F+S + G + K+ I
Sbjct: 142 EALLKFEKCF-GLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLII 200

Query: 166 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGH 216
               V+ ++KT   +L   ++ + +  + + F   L  + TY L++ +  +
Sbjct: 201 SWDEVSKLEKTSNVILT-ESIHVCSQGENHYFSMFLHINQTYLLMEQLANY 250



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 163
           +A+      F  +P  E LK+   C L     +    GK+ +SEN+ICF S+  G    +
Sbjct: 281 RAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQ-DGNQCSV 339

Query: 164 SIPAFSVTLIKKT 176
            IP   V  I KT
Sbjct: 340 IIPLREVLAIDKT 352


>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1120

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 3/111 (2%)

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQK-EILYQGKLFVSENWICFHSKVFGKDTKISI 165
           +A + F K F  +P +E L   ++C+  K  +  QG L++S N++ F+S + G + K+ I
Sbjct: 142 EALLKFEKCF-GLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLII 200

Query: 166 PAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGH 216
               V+ ++KT   +L   ++ + +  + + F   L  + TY L++ +  +
Sbjct: 201 SWDEVSKLEKTSNVILT-ESIHVCSQGENHYFSMFLHINQTYLLMEQLANY 250



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)

Query: 107 KANMHFHKLFLSVPTEEPLKQSFTCALQKEILY---QGKLFVSENWICFHSKVFGKDTKI 163
           +A+      F  +P  E LK+   C L     +    GK+ +SEN+ICF S+  G    +
Sbjct: 281 RAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQ-DGNQCSV 339

Query: 164 SIPAFSVTLIKKT 176
            IP   V  I KT
Sbjct: 340 IIPLREVLAIDKT 352


>gi|67763814 death-inducing-protein [Homo sapiens]
          Length = 578

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 18/119 (15%)

Query: 111 HFHKLFLSVPTEEPL---KQSFTCAL-------QKEILYQGKLFVSENWICFHSKVFG-- 158
           +FH++F     E PL   +  + C L         + +  G L+V+EN++CF S   G  
Sbjct: 446 NFHEIFNLTENERPLAVCENGWRCCLINRDRKMPTDYIRNGVLYVTENYLCFESSKSGSS 505

Query: 159 KDTKISIPAFSVTLIKKTKTALLVPNA---LIIATVTDR--YIFVSLLSRDSTYKLLKS 212
           K  K+ I    +T I+K K   ++P +   + ++T + +   +F +++ RD  ++ + S
Sbjct: 506 KRNKV-IKLVDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETILS 563


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 35.8 bits (81), Expect = 0.078
 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 12/99 (12%)

Query: 19  KRESKLGSAHSEAENGVEEKKKACR------SPTAQSPTPSVEADSPDQKKIIS----LW 68
           K E K  + H  + N    K+ A +      SP    P+   + +   +K+ IS    L 
Sbjct: 783 KTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLK 842

Query: 69  SKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYK 107
           S S+ +  +  S KN   T  +   KTE K SSSS + K
Sbjct: 843 SSSNSNKETSGSSKNSSSTSKQK--KTEGKTSSSSKEVK 879


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 35/140 (25%), Positives = 59/140 (42%), Gaps = 22/140 (15%)

Query: 1   MTELQQDVEDTKPAKVLGKRESKLG---SAHSEAENGVEEKKKACRSPTAQSPTPSVEA- 56
           + E ++ + +    ++   RE  L    S+  + E   + KKK+CRS ++ S + S  + 
Sbjct: 58  LAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSS 117

Query: 57  -DSPDQ----------KKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQ 105
            DS D+          KK  S  S  S    S +  K   K + K+  +TE++K   S  
Sbjct: 118 SDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLS 177

Query: 106 YKANMHFHKLFLSVPTEEPL 125
            K          S P ++PL
Sbjct: 178 KKRKK-------SYPDDKPL 190



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 9/108 (8%)

Query: 3   ELQQDVEDTKP-AKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQ 61
           E+++ +E+ K  +K L + E K+       EN  +E +K+     + + + S + +   +
Sbjct: 43  EVKKQLENKKTGSKALAEFEEKMN------ENWKKELEKSREKLLSGNESSSKKRERKKK 96

Query: 62  KKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKAN 109
           +K  S  S SS   +  +S  +D + E K   K  R+K   +  YK++
Sbjct: 97  RKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGK--RRKKKKNRSYKSS 142


>gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
           sapiens]
          Length = 1045

 Score = 33.5 bits (75), Expect = 0.38
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 11/105 (10%)

Query: 11  TKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSP---TPSVEAD---SP----D 60
           + P  VLGK E ++   H ++   ++ KK+  RS +  SP     SV  D   SP     
Sbjct: 533 SSPHSVLGKDE-QINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRH 591

Query: 61  QKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQ 105
           +K+  S  S S     S    KN  K   K   K++R +S  SS+
Sbjct: 592 RKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSR 636


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score = 33.5 bits (75), Expect = 0.38
 Identities = 19/85 (22%), Positives = 38/85 (44%), Gaps = 5/85 (5%)

Query: 26  SAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLASDKNDC 85
           +    A+     ++K C SP    P+P    D P  +     +S +   G+S ++  + C
Sbjct: 637 ACRDSAKERASSRRKGCSSPPPPEPSPQA-PDGPSLQLPAQTFSSAPVPGSSSSTLPSSC 695

Query: 86  ----KTESKNDPKTERKKSSSSSQY 106
               + E+ +DP+TE   +   S++
Sbjct: 696 EQSRQAETPSDPQTETLSAMDVSEF 720


>gi|4557509 cylicin 2 [Homo sapiens]
          Length = 348

 Score = 33.1 bits (74), Expect = 0.50
 Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 7/96 (7%)

Query: 18  GKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADS------PDQKKIISLWSKS 71
           GK+++  G    +A+   +E KK  +     S T S   D        D  K     +K 
Sbjct: 247 GKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKK 306

Query: 72  SFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYK 107
             +  S A  K D K  +K D K + KK++   + K
Sbjct: 307 DTEKES-ADSKKDAKKNAKKDAKKDAKKNAKKDEKK 341



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 21/117 (17%)

Query: 2   TELQQDVEDTKPAKVLGKRESKLG-----------SAHSEAENGVEEKKKACRSPTAQSP 50
           TE + +   T+     GK++SK G           +   + E+G ++  K   S  A+  
Sbjct: 204 TESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD 263

Query: 51  TPSVEADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYK 107
              ++    D+KK       SS D  S    K+D K ESK D   + KK +     K
Sbjct: 264 AKEIKKGKKDKKK------PSSTDSDS----KDDVKKESKKDATKDAKKVAKKDTEK 310


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 33.1 bits (74), Expect = 0.50
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 12/100 (12%)

Query: 8   VEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISL 67
           VED +P K           + + A    EEKKK       +S     +  S  + K  S 
Sbjct: 163 VEDEEPKK-----------STTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSE 211

Query: 68  WSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYK 107
            S S  D  + +SD+ D K  +K   K E+KK   S +YK
Sbjct: 212 DSDSDSDSETDSSDE-DNKRRAKKAKKKEKKKKHRSKKYK 250


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 32.7 bits (73), Expect = 0.66
 Identities = 22/84 (26%), Positives = 38/84 (45%)

Query: 21  ESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLAS 80
           +S   S+ S++ N  +    +  S +++S   S  +DS       S  S SS   +S +S
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732

Query: 81  DKNDCKTESKNDPKTERKKSSSSS 104
           D +D    S +   ++   SS SS
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSS 756



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 21/97 (21%), Positives = 38/97 (39%)

Query: 7   DVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIIS 66
           D  D+  +      +S   S  S++ N  +  + +  S  + S   S  +DS D     +
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952

Query: 67  LWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSS 103
               S+   +S +SD +D  +   +D       S SS
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 21/84 (25%), Positives = 35/84 (41%)

Query: 21   ESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLAS 80
            +S   S  SE+ +  +    +  S ++ S   S  +DS D        + S    +S +S
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133

Query: 81   DKNDCKTESKNDPKTERKKSSSSS 104
            D +D    S +   +E   SS SS
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSS 1157



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 20/84 (23%), Positives = 36/84 (42%)

Query: 21   ESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLAS 80
            +S   S  S++ N  +    +  S ++ S   S  +DS D          S+   +S +S
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064

Query: 81   DKNDCKTESKNDPKTERKKSSSSS 104
            D +D    S +   ++  +SS SS
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSS 1088



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 20/84 (23%), Positives = 36/84 (42%)

Query: 21   ESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLAS 80
            +S   S  S++ N  +    +  S ++ S   S  +DS D     +    S    +S +S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070

Query: 81   DKNDCKTESKNDPKTERKKSSSSS 104
            D +D    S +   ++   SS+SS
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSS 1094



 Score = 29.3 bits (64), Expect = 7.3
 Identities = 20/84 (23%), Positives = 35/84 (41%)

Query: 21   ESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLAS 80
            +S   S  S++ N  +    +  S ++ S   S  +DS D          S    +S +S
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1226

Query: 81   DKNDCKTESKNDPKTERKKSSSSS 104
            D +D    S +   ++   SS+SS
Sbjct: 1227 DSSDSNESSDSSDSSDSSDSSNSS 1250



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 19/84 (22%), Positives = 36/84 (42%)

Query: 21  ESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLAS 80
           +S   S  S++ +  +    +  S ++ S   S  +DS D        + S  + +S +S
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792

Query: 81  DKNDCKTESKNDPKTERKKSSSSS 104
           D +D    S +   ++   SS SS
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSS 816



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 19/85 (22%), Positives = 35/85 (41%)

Query: 21   ESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLAS 80
            +S   S  S++ +  +    +  S ++ S   S  +DS D          S    +S +S
Sbjct: 999  DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058

Query: 81   DKNDCKTESKNDPKTERKKSSSSSQ 105
            D +D    S +   ++   SS SS+
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSE 1083



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 20/84 (23%), Positives = 35/84 (41%)

Query: 21   ESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKIISLWSKSSFDGASLAS 80
            +S   S  S++ N  +    +  S ++ S   S  +DS D          S+   +S +S
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187

Query: 81   DKNDCKTESKNDPKTERKKSSSSS 104
            D +D    S +   ++   SS SS
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSS 1211


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 32.7 bits (73), Expect = 0.66
 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 6/120 (5%)

Query: 5   QQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPDQKKI 64
           +  ++++ P ++    E+   S   E E  V    +  R P A+     V A S   K  
Sbjct: 641 EPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKV--DVIAGSSKMKGF 698

Query: 65  ISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYKANMHFHKLFLSVPTEEP 124
            S  S+SS + +S  SD  D +TE    PK+++K      Q K + H H+     P   P
Sbjct: 699 SSSESESSSESSS--SDSEDSETEMA--PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVP 754


>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
          Length = 910

 Score = 32.7 bits (73), Expect = 0.66
 Identities = 29/144 (20%), Positives = 64/144 (44%), Gaps = 19/144 (13%)

Query: 154 SKVFGKDTKISIPAF--SVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSR----DSTY 207
           S + G  T+ ++ +F  ++++I +   +  V N   + ++      +SL S     +ST 
Sbjct: 312 SMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTM 371

Query: 208 KLLKSVCGHLENTSVGNSPNPSSAENSFRADR-------------PSSLPLDFNDEFSDL 254
           + + S+  ++ N++   +      E  + + R             P++LPL+F+ +F D 
Sbjct: 372 EDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDW 431

Query: 255 DGVVQQRRQDMEGYSSSGSQTPES 278
            G+   + Q   GYS      P++
Sbjct: 432 KGIPVNKSQLKRGYSYQIKMCPQN 455


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 32.3 bits (72), Expect = 0.86
 Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 1   MTELQQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPD 60
           M+E + D +D+    +  K++SK G+   +   G+ +K+K     +   P  S      +
Sbjct: 137 MSETESDSKDS----LKKKKKSKDGTEKEKDIKGLSKKRKMY---SEDKPLSSESLSESE 189

Query: 61  QKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSS 104
             + +    K S +    A++K   K + K   K ++KK++SSS
Sbjct: 190 YIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSS 233



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 6/113 (5%)

Query: 1   MTELQQDVEDTKPAKVLGKRESKLGSAHSEA---ENGVEEKKKACR---SPTAQSPTPSV 54
           + E ++ + +    ++   RE  L  + S +   +   +EKKK+ R   S ++ S + S 
Sbjct: 48  LAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSS 107

Query: 55  EADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYK 107
            +DS D+ K      K   + +  +S+ +  +TES +    ++KK S     K
Sbjct: 108 SSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEK 160


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 32.3 bits (72), Expect = 0.86
 Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 1   MTELQQDVEDTKPAKVLGKRESKLGSAHSEAENGVEEKKKACRSPTAQSPTPSVEADSPD 60
           M+E + D +D+    +  K++SK G+   +   G+ +K+K     +   P  S      +
Sbjct: 147 MSETESDSKDS----LKKKKKSKDGTEKEKDIKGLSKKRKMY---SEDKPLSSESLSESE 199

Query: 61  QKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSS 104
             + +    K S +    A++K   K + K   K ++KK++SSS
Sbjct: 200 YIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSS 243



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 6/113 (5%)

Query: 1   MTELQQDVEDTKPAKVLGKRESKLGSAHSEA---ENGVEEKKKACR---SPTAQSPTPSV 54
           + E ++ + +    ++   RE  L  + S +   +   +EKKK+ R   S ++ S + S 
Sbjct: 58  LAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSS 117

Query: 55  EADSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKKSSSSSQYK 107
            +DS D+ K      K   + +  +S+ +  +TES +    ++KK S     K
Sbjct: 118 SSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEK 170


>gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens]
          Length = 170

 Score = 32.3 bits (72), Expect = 0.86
 Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 7/103 (6%)

Query: 4   LQQDVEDTKPAKVLGKRESKL-------GSAHSEAENGVEEKKKACRSPTAQSPTPSVEA 56
           LQQ + +T   +   K+ SK         S  S +++  E ++ +  S +  S T    +
Sbjct: 65  LQQSIGETNVERKAKKKRSKSVTSSSSSSSDSSASDSSSESEETSTSSSSEDSDTDESSS 124

Query: 57  DSPDQKKIISLWSKSSFDGASLASDKNDCKTESKNDPKTERKK 99
            S       +  S S  D  S +S  +   T+S +D +  +KK
Sbjct: 125 SSSSSASSTTSSSSSDSDSDSSSSSSSSTSTDSSSDDEPPKKK 167


>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 7/95 (7%)

Query: 215 GHLENTSVGNSPNPSSAENSFR--ADRPSSLPLDFNDEFSDLDGVVQQRRQDMEGYS-SS 271
           G L + S   SP+PS+A   FR  +D P+SLP    +  SD+  +  +   D E +    
Sbjct: 613 GGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP---ENNMSDVSQLKSEESSDDESHPLRE 669

Query: 272 GSQTPESENSRDFHATESQTVLNVSKGEAKPTRAD 306
           G+ + +S+ S +F + +S     +S+  +K + ++
Sbjct: 670 GACSSQSQESGEF-SLQSSNASKLSQCSSKDSDSE 703


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,039,865
Number of Sequences: 37866
Number of extensions: 708834
Number of successful extensions: 2554
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 2370
Number of HSP's gapped (non-prelim): 253
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.