Search of human proteins with 226423903

Search of human proteins with 226423903

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226423903 splA/ryanodine receptor domain and SOCS box
containing 2 isoform 1 [Homo sapiens]
         (263 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226423903 splA/ryanodine receptor domain and SOCS box contain...   548   e-156
gi|14249178 splA/ryanodine receptor domain and SOCS box containi...   548   e-156
gi|226423905 splA/ryanodine receptor domain and SOCS box contain...   465   e-131
gi|18254460 splA/ryanodine receptor domain and SOCS box containi...   267   6e-72
gi|18141316 splA/ryanodine receptor domain and SOCS box containi...   258   3e-69
gi|157743247 F-box protein 45 [Homo sapiens]                          160   8e-40
gi|27552770 splA/ryanodine receptor domain and SOCS box containi...    54   1e-07
gi|94721248 ankyrin repeat and SOCS box-containing protein 1 [Ho...    41   0.001
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]     40   0.003
gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo sapi...    39   0.005
gi|22208951 ankyrin repeat and SOCS box-containing protein 3 iso...    39   0.006
gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isof...    39   0.006
gi|18252778 ankyrin repeat and SOCS box-containing protein 2 [Ho...    38   0.010
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]       38   0.010
gi|24586688 ankyrin repeat and SOCS box-containing protein 16 [H...    37   0.013
gi|18254474 ankyrin repeat and SOCS box-containing protein 11 is...    35   0.087
gi|60218887 ankyrin repeat and SOCS box-containing protein 11 is...    35   0.087
gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2...    35   0.087
gi|215598819 ankyrin repeat and SOCS box-containing 10 isoform 1...    35   0.087
gi|215598806 ankyrin repeat and SOCS box-containing 10 isoform 3...    35   0.087
gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]    34   0.15 
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...    33   0.25 
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...    33   0.25 
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...    33   0.25 
gi|7706379 ankyrin repeat and SOCS box-containing protein 4 isof...    33   0.33 
gi|218505706 ankyrin repeat and SOCS box-containing 14 isoform 1...    32   0.43 
gi|18390333 ankyrin repeat and SOCS box-containing 14 isoform 2 ...    32   0.43 
gi|239752719 PREDICTED: hypothetical protein [Homo sapiens]            31   0.96 
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]    31   0.96 
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             31   1.3  

>gi|226423903 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score =  548 bits (1412), Expect = e-156
 Identities = 263/263 (100%), Positives = 263/263 (100%)

Query: 1   MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK 60
           MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK
Sbjct: 1   MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK 60

Query: 61  EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY 120
           EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY
Sbjct: 61  EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY 120

Query: 121 AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY 180
           AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY
Sbjct: 121 AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY 180

Query: 181 AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLG 240
           AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLG
Sbjct: 181 AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLG 240

Query: 241 DTRLGQVSALPLPPAMKRYLLYQ 263
           DTRLGQVSALPLPPAMKRYLLYQ
Sbjct: 241 DTRLGQVSALPLPPAMKRYLLYQ 263


>gi|14249178 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score =  548 bits (1412), Expect = e-156
 Identities = 263/263 (100%), Positives = 263/263 (100%)

Query: 1   MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK 60
           MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK
Sbjct: 1   MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK 60

Query: 61  EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY 120
           EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY
Sbjct: 61  EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY 120

Query: 121 AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY 180
           AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY
Sbjct: 121 AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY 180

Query: 181 AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLG 240
           AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLG
Sbjct: 181 AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLG 240

Query: 241 DTRLGQVSALPLPPAMKRYLLYQ 263
           DTRLGQVSALPLPPAMKRYLLYQ
Sbjct: 241 DTRLGQVSALPLPPAMKRYLLYQ 263


>gi|226423905 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 2 [Homo sapiens]
          Length = 267

 Score =  465 bits (1196), Expect = e-131
 Identities = 222/223 (99%), Positives = 222/223 (99%)

Query: 1   MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK 60
           MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK
Sbjct: 1   MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVK 60

Query: 61  EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY 120
           EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY
Sbjct: 61  EGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHY 120

Query: 121 AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY 180
           AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY
Sbjct: 121 AALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY 180

Query: 181 AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAE 223
           AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERR E
Sbjct: 181 AIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRGE 223


>gi|18254460 splA/ryanodine receptor domain and SOCS box containing
           4 [Homo sapiens]
          Length = 273

 Score =  267 bits (683), Expect = 6e-72
 Identities = 134/240 (55%), Positives = 164/240 (68%), Gaps = 2/240 (0%)

Query: 26  PEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGG-LYFERRPVAQSTDGARGKRGY 84
           P  L++LL  P   L  Q RH WNP+D S N+ VK+   L F R PVAQSTDG RGK G+
Sbjct: 34  PARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGH 93

Query: 85  SRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKLYHQS 144
           +RGLHAW+I+WP  QRGTHAVVGVATA APL +  Y AL+GS++ESWGWD+GR +LYH  
Sbjct: 94  ARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGSDAESWGWDLGRSRLYHDG 153

Query: 145 KGPGAPQYPAGT-QGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAV 203
           K      YPA     E   +P+ LLVVLDM+EGTL + + G YLG AFRGLKG+ LYP V
Sbjct: 154 KNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVV 213

Query: 204 SAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ 263
           SAVWG C+V +RY+     EP  L+ L R  +R  LG  RL  +S+LPLP ++K YL YQ
Sbjct: 214 SAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ 273


>gi|18141316 splA/ryanodine receptor domain and SOCS box containing
           1 [Homo sapiens]
          Length = 273

 Score =  258 bits (660), Expect = 3e-69
 Identities = 131/244 (53%), Positives = 159/244 (65%), Gaps = 2/244 (0%)

Query: 22  DLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGG-LYFERRPVAQSTDGARG 80
           D   P  L+ LL  PP     Q  H WN  D S N+ VKE   L F R PVAQSTD  RG
Sbjct: 30  DYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRG 89

Query: 81  KRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKL 140
           K GY+RGLH W+I+W + QRGTHAVVGVATA APL +  Y  L+G+N ESWGWD+GR +L
Sbjct: 90  KVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTTLVGNNHESWGWDLGRNRL 149

Query: 141 YHQSKGPGAPQYPAGTQ-GEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTL 199
           YH  K   +  YPA  +  E   VP+  LV LDM++GTL + + G Y+G AFRGLKG+ L
Sbjct: 150 YHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMGVAFRGLKGKKL 209

Query: 200 YPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRY 259
           YP VSAVWG C++R+RYL     EP  L+ L R  VR  LG  RLG++  LPLP ++K Y
Sbjct: 210 YPVVSAVWGHCEIRMRYLNGLDPEPLPLMDLCRRSVRLALGRERLGEIHTLPLPASLKAY 269

Query: 260 LLYQ 263
           LLYQ
Sbjct: 270 LLYQ 273


>gi|157743247 F-box protein 45 [Homo sapiens]
          Length = 286

 Score =  160 bits (406), Expect = 8e-40
 Identities = 82/177 (46%), Positives = 113/177 (63%), Gaps = 7/177 (3%)

Query: 45  RHGWNPKDCSENIEVKEGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISW--PLEQRGT 102
           +H ++  DCS N+ +K+ G    R P+AQSTDGAR K G+S G HAWE+ W  PL   GT
Sbjct: 111 QHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPL---GT 167

Query: 103 HAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLE 162
            AV+G+AT  AP+Q   Y ALLGS+ +SWGW++    L H  +  G+  +P      + +
Sbjct: 168 VAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGS--FPQCNNAPKYQ 225

Query: 163 VPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGE 219
           + ER+ V+LDME+ TL +  G  +LG AFRGL    LYPAVSAV+G  +V + YLG+
Sbjct: 226 IGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGK 282


>gi|27552770 splA/ryanodine receptor domain and SOCS box containing
           3 [Homo sapiens]
          Length = 355

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 17/189 (8%)

Query: 75  TDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQ--TDHYAALLGSNSESWG 132
           T   RG +    G H WEI       GT  +VG+ T+   L      + +LLG + +SWG
Sbjct: 135 TAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWG 194

Query: 133 WDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFR 192
                G L+H  KG          QG  + V       LD   GTL +      +G A  
Sbjct: 195 LSY-TGLLHH--KGDKTSFSSRFGQGSIIGVH------LDTWHGTLTFFKNRKCIGVAAT 245

Query: 193 GLKGRTLYPAVSAVWGQCQVRI-RYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALP 251
            L+ +  YP V +   +  +++ R      +  +   H  R  +R + GDT    +  LP
Sbjct: 246 KLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQ-LRPDSGDT----LEGLP 300

Query: 252 LPPAMKRYL 260
           LPP +K+ L
Sbjct: 301 LPPGLKQVL 309


>gi|94721248 ankyrin repeat and SOCS box-containing protein 1 [Homo
           sapiens]
          Length = 335

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 20/45 (44%), Positives = 30/45 (66%)

Query: 219 ERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ 263
           E R+ P +LL L R+ VR  LG  RL  + +LPLP  +K++LL++
Sbjct: 291 EARSVPRTLLCLCRVAVRRALGKHRLHLIPSLPLPDPIKKFLLHE 335


>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
          Length = 740

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 51/199 (25%), Positives = 82/199 (41%), Gaps = 27/199 (13%)

Query: 9   GSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGW--NPKDCSENIEVKEGGLYF 66
           G+ S P  Q +Y  L   +  E          GA   + W  NP D      +   GL  
Sbjct: 54  GAFSIPVIQIVYETLKDQQ--EGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCC 111

Query: 67  ERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGS 126
           + R V +   G R  +G  +G H +E+S     +G    VG +T  A L        LG+
Sbjct: 112 QSREVKE-WHGCRATKGLMKGKHYYEVS--CHDQGL-CRVGWSTMQASLD-------LGT 160

Query: 127 NSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTY 186
           +   +G+  G GK  H  +            GE+  + + +   LD+++G + ++  G  
Sbjct: 161 DKFGFGFG-GTGKKSHNKQ--------FDNYGEEFTMHDTIGCYLDIDKGHVKFSKNGKD 211

Query: 187 LGPAFR---GLKGRTLYPA 202
           LG AF     +K + L+PA
Sbjct: 212 LGLAFEIPPHMKNQALFPA 230


>gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo
           sapiens]
          Length = 588

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 21/43 (48%), Positives = 29/43 (67%), Gaps = 3/43 (6%)

Query: 224 PHSLLHLSRLCVRHNLGDTRLGQ---VSALPLPPAMKRYLLYQ 263
           P SL HL RL +R  +G  +L Q   V  LPLPPA++RY+L++
Sbjct: 534 PCSLKHLCRLKIRRLMGLQKLCQPASVEKLPLPPAIQRYILFK 576


>gi|22208951 ankyrin repeat and SOCS box-containing protein 3
           isoform b [Homo sapiens]
          Length = 445

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 3/70 (4%)

Query: 197 RTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRL---GQVSALPLP 253
           +TL PAV  +          L +  A   SL HL RL +R +L   RL     +S LPLP
Sbjct: 359 KTLAPAVERMLSARASNAWILQQHIATVPSLTHLCRLEIRSSLKSERLRSDSYISQLPLP 418

Query: 254 PAMKRYLLYQ 263
            ++  YLLY+
Sbjct: 419 RSLHNYLLYE 428


>gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isoform
           a [Homo sapiens]
          Length = 518

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 3/70 (4%)

Query: 197 RTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRL---GQVSALPLP 253
           +TL PAV  +          L +  A   SL HL RL +R +L   RL     +S LPLP
Sbjct: 432 KTLAPAVERMLSARASNAWILQQHIATVPSLTHLCRLEIRSSLKSERLRSDSYISQLPLP 491

Query: 254 PAMKRYLLYQ 263
            ++  YLLY+
Sbjct: 492 RSLHNYLLYE 501


>gi|18252778 ankyrin repeat and SOCS box-containing protein 2 [Homo
           sapiens]
          Length = 587

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 19/45 (42%), Positives = 25/45 (55%)

Query: 219 ERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ 263
           E+   P  L HL RL VR  +G  R+  +  LPLP  + RYL Y+
Sbjct: 540 EKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYE 584


>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 14/127 (11%)

Query: 80  GKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGK 139
           GK G+S+G+H WE++  +++   H       A   +  D    +LG + ++W   +   +
Sbjct: 570 GKTGFSKGIHYWELT--VDRYDNHPDPAFGVARMDVMKD---VMLGKDDKAWAMYVDNNR 624

Query: 140 LYHQSKGPGAPQYPAG-TQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGP-AFRGLKGR 197
            +         +   G T+G  +       V+LD+    L + I     GP AF  ++G 
Sbjct: 625 SWFMHNNSHTNRTEGGITKGATIG------VLLDLNRKNLTFFINDEQQGPIAFDNVEG- 677

Query: 198 TLYPAVS 204
             +PAVS
Sbjct: 678 LFFPAVS 684


>gi|24586688 ankyrin repeat and SOCS box-containing protein 16 [Homo
           sapiens]
          Length = 453

 Score = 37.4 bits (85), Expect = 0.013
 Identities = 18/39 (46%), Positives = 23/39 (58%)

Query: 223 EPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLL 261
           +P  L HL+RL VR  LG       + LPLPP ++ YLL
Sbjct: 407 QPRQLQHLARLAVRARLGSRCRQGATRLPLPPLLRDYLL 445


>gi|18254474 ankyrin repeat and SOCS box-containing protein 11
           isoform a [Homo sapiens]
          Length = 323

 Score = 34.7 bits (78), Expect = 0.087
 Identities = 19/43 (44%), Positives = 24/43 (55%)

Query: 221 RAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ 263
           R  P +L  L RLCVR  LG      +  L LP  ++R+LLYQ
Sbjct: 281 REGPPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ 323


>gi|60218887 ankyrin repeat and SOCS box-containing protein 11
           isoform b [Homo sapiens]
          Length = 302

 Score = 34.7 bits (78), Expect = 0.087
 Identities = 19/43 (44%), Positives = 24/43 (55%)

Query: 221 RAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ 263
           R  P +L  L RLCVR  LG      +  L LP  ++R+LLYQ
Sbjct: 260 REGPPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ 302


>gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2
           [Homo sapiens]
          Length = 474

 Score = 34.7 bits (78), Expect = 0.087
 Identities = 17/38 (44%), Positives = 23/38 (60%)

Query: 223 EPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYL 260
           +P SL HLSR  +R +L  +    +  LPLPP + RYL
Sbjct: 428 QPRSLQHLSRCALRSHLEGSLPQALPRLPLPPRLLRYL 465


>gi|215598819 ankyrin repeat and SOCS box-containing 10 isoform 1
           [Homo sapiens]
          Length = 512

 Score = 34.7 bits (78), Expect = 0.087
 Identities = 17/38 (44%), Positives = 23/38 (60%)

Query: 223 EPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYL 260
           +P SL HLSR  +R +L  +    +  LPLPP + RYL
Sbjct: 466 QPRSLQHLSRCALRSHLEGSLPQALPRLPLPPRLLRYL 503


>gi|215598806 ankyrin repeat and SOCS box-containing 10 isoform 3
           [Homo sapiens]
          Length = 452

 Score = 34.7 bits (78), Expect = 0.087
 Identities = 17/38 (44%), Positives = 23/38 (60%)

Query: 223 EPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYL 260
           +P SL HLSR  +R +L  +    +  LPLPP + RYL
Sbjct: 406 QPRSLQHLSRCALRSHLEGSLPQALPRLPLPPRLLRYL 443


>gi|126131099 guanine nucleotide exchange factor p532 [Homo sapiens]
          Length = 4861

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 40/167 (23%), Positives = 62/167 (37%), Gaps = 20/167 (11%)

Query: 75   TDGARGK------RGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNS 128
            T G+ GK       G + G + W+     E RG      V  +  P+   ++     + S
Sbjct: 2052 THGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTC-VGVSRWPVHDFNHR----TTS 2106

Query: 129  ESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLG 188
            + W +    G LYH   G       + TQG+ +        VLDME  T+ +   G    
Sbjct: 2107 DMWLYRAYSGNLYHN--GEQTLTLSSFTQGDFITC------VLDMEARTISFGKNGEEPK 2158

Query: 189  PAFRGLKGRTLYPAVSAVWGQCQVRIRYLG-ERRAEPHSLLHLSRLC 234
             AF  +    LYP V         +++    + R  P  LL    +C
Sbjct: 2159 LAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPIC 2205


>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 33.1 bits (74), Expect = 0.25
 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 17/125 (13%)

Query: 84  YSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESW---GWDIGRGKL 140
           ++ G H WE+   +++ G    VG A A    +    AA LG N +SW    +D+     
Sbjct: 317 FATGRHYWEVD--VQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAF 374

Query: 141 YHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY--AIGGTYLGPAFRGLKGRT 198
           +   +    P+          +  +RL V LD E G L +    GG      FR      
Sbjct: 375 HDGQRSRLRPR----------DDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEP 424

Query: 199 LYPAV 203
           LYPA+
Sbjct: 425 LYPAL 429


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 33.1 bits (74), Expect = 0.25
 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 17/125 (13%)

Query: 84  YSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESW---GWDIGRGKL 140
           ++ G H WE+   +++ G    VG A A    +    AA LG N +SW    +D+     
Sbjct: 317 FATGRHYWEVD--VQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAF 374

Query: 141 YHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY--AIGGTYLGPAFRGLKGRT 198
           +   +    P+          +  +RL V LD E G L +    GG      FR      
Sbjct: 375 HDGQRSRLRPR----------DDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEP 424

Query: 199 LYPAV 203
           LYPA+
Sbjct: 425 LYPAL 429


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 33.1 bits (74), Expect = 0.25
 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 17/125 (13%)

Query: 84  YSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESW---GWDIGRGKL 140
           ++ G H WE+   +++ G    VG A A    +    AA LG N +SW    +D+     
Sbjct: 317 FATGRHYWEVD--VQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAF 374

Query: 141 YHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGY--AIGGTYLGPAFRGLKGRT 198
           +   +    P+          +  +RL V LD E G L +    GG      FR      
Sbjct: 375 HDGQRSRLRPR----------DDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEP 424

Query: 199 LYPAV 203
           LYPA+
Sbjct: 425 LYPAL 429


>gi|7706379 ankyrin repeat and SOCS box-containing protein 4 isoform
           a [Homo sapiens]
          Length = 426

 Score = 32.7 bits (73), Expect = 0.33
 Identities = 15/40 (37%), Positives = 24/40 (60%)

Query: 224 PHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ 263
           P +L+HLSR  +R  L +     +  L LP ++K+YLL +
Sbjct: 381 PRTLMHLSRCAIRRTLHNRCHRAIPLLSLPLSLKKYLLLE 420


>gi|218505706 ankyrin repeat and SOCS box-containing 14 isoform 1
           [Homo sapiens]
          Length = 423

 Score = 32.3 bits (72), Expect = 0.43
 Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 3/43 (6%)

Query: 224 PHSLLHLSRLCVRHNLGDTRLGQ---VSALPLPPAMKRYLLYQ 263
           P SL HL RL +R  +G   L     +S LPLP  +K Y+LY+
Sbjct: 367 PRSLKHLCRLKIRKCMGRLHLRCPVFMSFLPLPNRLKAYVLYK 409


>gi|18390333 ankyrin repeat and SOCS box-containing 14 isoform 2
           [Homo sapiens]
          Length = 302

 Score = 32.3 bits (72), Expect = 0.43
 Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 3/43 (6%)

Query: 224 PHSLLHLSRLCVRHNLGDTRLGQ---VSALPLPPAMKRYLLYQ 263
           P SL HL RL +R  +G   L     +S LPLP  +K Y+LY+
Sbjct: 246 PRSLKHLCRLKIRKCMGRLHLRCPVFMSFLPLPNRLKAYVLYK 288


>gi|239752719 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 158

 Score = 31.2 bits (69), Expect = 0.96
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 18/97 (18%)

Query: 89  HAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNS--ESWGWDIGRGKLYHQSKG 146
           H+W  SWP E R        ++ L P        LLG  +    WG +I  G L    K 
Sbjct: 26  HSWAASWPTEGR------QCSSGLLP------KPLLGLRTVGSGWGLNISFGLLTQSMKQ 73

Query: 147 PGAPQYPAGTQGEQLE--VPER--LLVVLDMEEGTLG 179
              P+  AG  G  LE  +P+    L + +++ G LG
Sbjct: 74  DHGPERGAGFLGAGLESSLPQMGWALTLRELQMGELG 110


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score = 31.2 bits (69), Expect = 0.96
 Identities = 33/125 (26%), Positives = 47/125 (37%), Gaps = 33/125 (26%)

Query: 80  GKRGYSRGLHAWEISWPLEQRGTHA-VVGVATALAPLQTDHYAALLGSNSESWG-WDIGR 137
           G +G+  G H WE+    E  G     VG A      ++ H+   +G    S G  D   
Sbjct: 477 GAQGFRSGRHYWEV----EVGGRRGWAVGAAR-----ESTHHKEKVGPGGSSVGSGDASS 527

Query: 138 GKLYHQSKGPGAPQYP--------AGTQGEQL--------------EVPERLLVVLDMEE 175
            + +H+ +    PQ P         GT G++               E P R  V LD E 
Sbjct: 528 SRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEA 587

Query: 176 GTLGY 180
           G LG+
Sbjct: 588 GRLGF 592


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 14/127 (11%)

Query: 80  GKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGK 139
           G   +S+G+H WE+   +++   H       A A +  D    +LG + ++W   +   +
Sbjct: 642 GTAAFSKGVHYWELH--VDRYDNHPDPAFGVARASVVKD---MMLGKDDKAWAMYVDNNR 696

Query: 140 LYHQSKGPGAPQYPAGT-QGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGP-AFRGLKGR 197
            +         +   G  +G  +       V+LD+ + TL + I G   GP AF  + G 
Sbjct: 697 SWFMHCNSHTNRTEGGVCKGATVG------VLLDLNKHTLTFFINGQQQGPTAFSHVDG- 749

Query: 198 TLYPAVS 204
              PA+S
Sbjct: 750 VFMPALS 756


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,110,276
Number of Sequences: 37866
Number of extensions: 611410
Number of successful extensions: 1755
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1718
Number of HSP's gapped (non-prelim): 47
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.