Search of human proteins with 226246554

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
         (7081 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226246554 hypothetical protein LOC643677 [Homo sapiens]           1.406e+04   0.0  
gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap...  8592   0.0  
gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sap...  8579   0.0  
gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sap...  8576   0.0  
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    85   3e-15
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    66   1e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    65   2e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     65   3e-09
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    63   9e-09
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    63   9e-09
gi|104526627 triadin [Homo sapiens]                                    62   2e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    60   6e-08
gi|71061468 centromere protein E [Homo sapiens]                        60   6e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       59   2e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               58   3e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     58   3e-07
gi|55770834 centromere protein F [Homo sapiens]                        58   3e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    58   4e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    57   7e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    57   7e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              57   7e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    56   1e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    56   1e-06
gi|148746195 trichohyalin [Homo sapiens]                               56   1e-06
gi|21735548 centrosomal protein 2 [Homo sapiens]                       55   2e-06
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  55   2e-06
gi|221219020 NYD-SP11 protein [Homo sapiens]                           55   3e-06
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       55   3e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    54   6e-06
gi|4557509 cylicin 2 [Homo sapiens]                                    54   7e-06

>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
          Length = 7081

 Score = 1.406e+04 bits (36499), Expect = 0.0
 Identities = 7081/7081 (100%), Positives = 7081/7081 (100%)

Query: 1    MSKQYYSFKKGVGSGLEDNTFMTLWDFLESWIIQNDWVAIFFIILLGIIFEIILMKACAS 60
            MSKQYYSFKKGVGSGLEDNTFMTLWDFLESWIIQNDWVAIFFIILLGIIFEIILMKACAS
Sbjct: 1    MSKQYYSFKKGVGSGLEDNTFMTLWDFLESWIIQNDWVAIFFIILLGIIFEIILMKACAS 60

Query: 61   FWKKPTLPEKGSSDVQETEDSCPKSRKLAPENWSVINSSSGERVGTFLEKRITSSLTSEE 120
            FWKKPTLPEKGSSDVQETEDSCPKSRKLAPENWSVINSSSGERVGTFLEKRITSSLTSEE
Sbjct: 61   FWKKPTLPEKGSSDVQETEDSCPKSRKLAPENWSVINSSSGERVGTFLEKRITSSLTSEE 120

Query: 121  KECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHT 180
            KECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHT
Sbjct: 121  KECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHT 180

Query: 181  EHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLF 240
            EHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLF
Sbjct: 181  EHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLF 240

Query: 241  LSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFP 300
            LSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFP
Sbjct: 241  LSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFP 300

Query: 301  GQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQ 360
            GQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQ
Sbjct: 301  GQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQ 360

Query: 361  SQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKN 420
            SQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKN
Sbjct: 361  SQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKN 420

Query: 421  AEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKT 480
            AEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKT
Sbjct: 421  AEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKT 480

Query: 481  PDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIA 540
            PDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIA
Sbjct: 481  PDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIA 540

Query: 541  LHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGIS 600
            LHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGIS
Sbjct: 541  LHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGIS 600

Query: 601  DITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSIT 660
            DITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSIT
Sbjct: 601  DITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSIT 660

Query: 661  QAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQ 720
            QAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQ
Sbjct: 661  QAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQ 720

Query: 721  SSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISPGSKMHKS 780
            SSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISPGSKMHKS
Sbjct: 721  SSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISPGSKMHKS 780

Query: 781  SEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDA 840
            SEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDA
Sbjct: 781  SEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDA 840

Query: 841  FHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCT 900
            FHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCT
Sbjct: 841  FHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCT 900

Query: 901  FKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQP 960
            FKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQP
Sbjct: 901  FKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQP 960

Query: 961  QTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIET 1020
            QTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIET
Sbjct: 961  QTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIET 1020

Query: 1021 TEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSET 1080
            TEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSET
Sbjct: 1021 TEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSET 1080

Query: 1081 KSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNV 1140
            KSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNV
Sbjct: 1081 KSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNV 1140

Query: 1141 IYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQD 1200
            IYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQD
Sbjct: 1141 IYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQD 1200

Query: 1201 EVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHA 1260
            EVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHA
Sbjct: 1201 EVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHA 1260

Query: 1261 ENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEE 1320
            ENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEE
Sbjct: 1261 ENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEE 1320

Query: 1321 KTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETV 1380
            KTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETV
Sbjct: 1321 KTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETV 1380

Query: 1381 SVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETAD 1440
            SVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETAD
Sbjct: 1381 SVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETAD 1440

Query: 1441 KTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVL 1500
            KTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVL
Sbjct: 1441 KTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVL 1500

Query: 1501 NCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPP 1560
            NCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPP
Sbjct: 1501 NCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPP 1560

Query: 1561 KALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLD 1620
            KALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLD
Sbjct: 1561 KALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLD 1620

Query: 1621 QFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSC 1680
            QFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSC
Sbjct: 1621 QFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSC 1680

Query: 1681 MPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLT 1740
            MPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLT
Sbjct: 1681 MPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLT 1740

Query: 1741 TKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSI 1800
            TKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSI
Sbjct: 1741 TKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSI 1800

Query: 1801 TSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFV 1860
            TSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFV
Sbjct: 1801 TSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFV 1860

Query: 1861 TKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGV 1920
            TKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGV
Sbjct: 1861 TKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGV 1920

Query: 1921 PTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMN 1980
            PTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMN
Sbjct: 1921 PTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMN 1980

Query: 1981 VQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQK 2040
            VQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQK
Sbjct: 1981 VQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQK 2040

Query: 2041 TKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDEN 2100
            TKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDEN
Sbjct: 2041 TKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDEN 2100

Query: 2101 PRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLK 2160
            PRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLK
Sbjct: 2101 PRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLK 2160

Query: 2161 AKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSM 2220
            AKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSM
Sbjct: 2161 AKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSM 2220

Query: 2221 IDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQR 2280
            IDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQR
Sbjct: 2221 IDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQR 2280

Query: 2281 NTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENH 2340
            NTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENH
Sbjct: 2281 NTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENH 2340

Query: 2341 GHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKP 2400
            GHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKP
Sbjct: 2341 GHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKP 2400

Query: 2401 PISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGF 2460
            PISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGF
Sbjct: 2401 PISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGF 2460

Query: 2461 QTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHL 2520
            QTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHL
Sbjct: 2461 QTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHL 2520

Query: 2521 TEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKE 2580
            TEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKE
Sbjct: 2521 TEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKE 2580

Query: 2581 SLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHS 2640
            SLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHS
Sbjct: 2581 SLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHS 2640

Query: 2641 PASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKT 2700
            PASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKT
Sbjct: 2641 PASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKT 2700

Query: 2701 EAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQ 2760
            EAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQ
Sbjct: 2701 EAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQ 2760

Query: 2761 QELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEYG 2820
            QELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEYG
Sbjct: 2761 QELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEYG 2820

Query: 2821 TASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTC 2880
            TASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTC
Sbjct: 2821 TASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTC 2880

Query: 2881 ILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRIS 2940
            ILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRIS
Sbjct: 2881 ILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRIS 2940

Query: 2941 SQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKG 3000
            SQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKG
Sbjct: 2941 SQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKG 3000

Query: 3001 QNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYIN 3060
            QNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYIN
Sbjct: 3001 QNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYIN 3060

Query: 3061 RKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSES 3120
            RKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSES
Sbjct: 3061 RKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSES 3120

Query: 3121 FLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKH 3180
            FLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKH
Sbjct: 3121 FLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKH 3180

Query: 3181 LSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQ 3240
            LSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQ
Sbjct: 3181 LSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQ 3240

Query: 3241 PPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTS 3300
            PPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTS
Sbjct: 3241 PPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTS 3300

Query: 3301 NTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTS 3360
            NTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTS
Sbjct: 3301 NTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTS 3360

Query: 3361 QTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLM 3420
            QTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLM
Sbjct: 3361 QTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLM 3420

Query: 3421 PQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSY 3480
            PQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSY
Sbjct: 3421 PQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSY 3480

Query: 3481 HKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITL 3540
            HKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITL
Sbjct: 3481 HKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITL 3540

Query: 3541 HSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLE 3600
            HSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLE
Sbjct: 3541 HSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLE 3600

Query: 3601 MQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQ 3660
            MQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQ
Sbjct: 3601 MQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQ 3660

Query: 3661 GKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMK 3720
            GKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMK
Sbjct: 3661 GKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMK 3720

Query: 3721 LTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLS 3780
            LTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLS
Sbjct: 3721 LTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLS 3780

Query: 3781 NVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMT 3840
            NVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMT
Sbjct: 3781 NVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMT 3840

Query: 3841 QEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQ 3900
            QEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQ
Sbjct: 3841 QEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQ 3900

Query: 3901 PIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKI 3960
            PIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKI
Sbjct: 3901 PIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKI 3960

Query: 3961 QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKC 4020
            QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKC
Sbjct: 3961 QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKC 4020

Query: 4021 ISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEP 4080
            ISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEP
Sbjct: 4021 ISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEP 4080

Query: 4081 SVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGD 4140
            SVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGD
Sbjct: 4081 SVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGD 4140

Query: 4141 ITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEA 4200
            ITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEA
Sbjct: 4141 ITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEA 4200

Query: 4201 QEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDK 4260
            QEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDK
Sbjct: 4201 QEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDK 4260

Query: 4261 NEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPS 4320
            NEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPS
Sbjct: 4261 NEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPS 4320

Query: 4321 EGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRD 4380
            EGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRD
Sbjct: 4321 EGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRD 4380

Query: 4381 GEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSL 4440
            GEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSL
Sbjct: 4381 GEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSL 4440

Query: 4441 TCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQ 4500
            TCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQ
Sbjct: 4441 TCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQ 4500

Query: 4501 KEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQER 4560
            KEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQER
Sbjct: 4501 KEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQER 4560

Query: 4561 KSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDI 4620
            KSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDI
Sbjct: 4561 KSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDI 4620

Query: 4621 TGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKA 4680
            TGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKA
Sbjct: 4621 TGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKA 4680

Query: 4681 QEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPT 4740
            QEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPT
Sbjct: 4681 QEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPT 4740

Query: 4741 KPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRK 4800
            KPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRK
Sbjct: 4741 KPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRK 4800

Query: 4801 EPQWGMKERAGQKQDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANS 4860
            EPQWGMKERAGQKQDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANS
Sbjct: 4801 EPQWGMKERAGQKQDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANS 4860

Query: 4861 NEGISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSL 4920
            NEGISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSL
Sbjct: 4861 NEGISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSL 4920

Query: 4921 HIEEQGEGVQESKKEPGVVPRKSASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQD 4980
            HIEEQGEGVQESKKEPGVVPRKSASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQD
Sbjct: 4921 HIEEQGEGVQESKKEPGVVPRKSASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQD 4980

Query: 4981 SSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLS 5040
            SSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLS
Sbjct: 4981 SSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLS 5040

Query: 5041 DILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKV 5100
            DILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKV
Sbjct: 5041 DILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKV 5100

Query: 5101 SLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKM 5160
            SLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKM
Sbjct: 5101 SLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKM 5160

Query: 5161 YLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQ 5220
            YLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQ
Sbjct: 5161 YLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQ 5220

Query: 5221 EESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSI 5280
            EESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSI
Sbjct: 5221 EESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSI 5280

Query: 5281 LIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHI 5340
            LIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHI
Sbjct: 5281 LIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHI 5340

Query: 5341 GETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTE 5400
            GETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTE
Sbjct: 5341 GETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTE 5400

Query: 5401 LHVNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVL 5460
            LHVNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVL
Sbjct: 5401 LHVNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVL 5460

Query: 5461 PLMPSALPDTEKTADAEARSGDVRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSH 5520
            PLMPSALPDTEKTADAEARSGDVRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSH
Sbjct: 5461 PLMPSALPDTEKTADAEARSGDVRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSH 5520

Query: 5521 ILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGS 5580
            ILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGS
Sbjct: 5521 ILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGS 5580

Query: 5581 SCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQP 5640
            SCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQP
Sbjct: 5581 SCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQP 5640

Query: 5641 SRVRSEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSY 5700
            SRVRSEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSY
Sbjct: 5641 SRVRSEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSY 5700

Query: 5701 PTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRKISKELYVTLGTPANSKGFSVSERY 5760
            PTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRKISKELYVTLGTPANSKGFSVSERY
Sbjct: 5701 PTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRKISKELYVTLGTPANSKGFSVSERY 5760

Query: 5761 AHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWN 5820
            AHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWN
Sbjct: 5761 AHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWN 5820

Query: 5821 APQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSL 5880
            APQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSL
Sbjct: 5821 APQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSL 5880

Query: 5881 QMLPGIHMDMTEIDPAKGGRKQALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQT 5940
            QMLPGIHMDMTEIDPAKGGRKQALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQT
Sbjct: 5881 QMLPGIHMDMTEIDPAKGGRKQALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQT 5940

Query: 5941 DANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRM 6000
            DANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRM
Sbjct: 5941 DANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRM 6000

Query: 6001 DTSSSAHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRN 6060
            DTSSSAHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRN
Sbjct: 6001 DTSSSAHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRN 6060

Query: 6061 VLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNR 6120
            VLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNR
Sbjct: 6061 VLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNR 6120

Query: 6121 KKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPN 6180
            KKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPN
Sbjct: 6121 KKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPN 6180

Query: 6181 TSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKA 6240
            TSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKA
Sbjct: 6181 TSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKA 6240

Query: 6241 QTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVW 6300
            QTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVW
Sbjct: 6241 QTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVW 6300

Query: 6301 DMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQ 6360
            DMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQ
Sbjct: 6301 DMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQ 6360

Query: 6361 DKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHL 6420
            DKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHL
Sbjct: 6361 DKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHL 6420

Query: 6421 ESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPN 6480
            ESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPN
Sbjct: 6421 ESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPN 6480

Query: 6481 SKHKHQKDSPLASNMKTLIVDVSSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQN 6540
            SKHKHQKDSPLASNMKTLIVDVSSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQN
Sbjct: 6481 SKHKHQKDSPLASNMKTLIVDVSSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQN 6540

Query: 6541 HSVKEKGKLLMHFSVKTLEIQMKAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQN 6600
            HSVKEKGKLLMHFSVKTLEIQMKAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQN
Sbjct: 6541 HSVKEKGKLLMHFSVKTLEIQMKAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQN 6600

Query: 6601 RILLLSEEKSLHQIDLDLQYKYLRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGG 6660
            RILLLSEEKSLHQIDLDLQYKYLRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGG
Sbjct: 6601 RILLLSEEKSLHQIDLDLQYKYLRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGG 6660

Query: 6661 QSGSLSIDTELLEQHISFKKQSPHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSES 6720
            QSGSLSIDTELLEQHISFKKQSPHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSES
Sbjct: 6661 QSGSLSIDTELLEQHISFKKQSPHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSES 6720

Query: 6721 EFHVTPEKNKQYHVWFQERNTCESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPAD 6780
            EFHVTPEKNKQYHVWFQERNTCESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPAD
Sbjct: 6721 EFHVTPEKNKQYHVWFQERNTCESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPAD 6780

Query: 6781 LDECSCLEVSESEECVFLEANSYLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSG 6840
            LDECSCLEVSESEECVFLEANSYLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSG
Sbjct: 6781 LDECSCLEVSESEECVFLEANSYLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSG 6840

Query: 6841 SHCTRECRKETLIITPPSCKSHKSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSE 6900
            SHCTRECRKETLIITPPSCKSHKSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSE
Sbjct: 6841 SHCTRECRKETLIITPPSCKSHKSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSE 6900

Query: 6901 EKISWTTKSRTSYSSAPLTESNIKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDH 6960
            EKISWTTKSRTSYSSAPLTESNIKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDH
Sbjct: 6901 EKISWTTKSRTSYSSAPLTESNIKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDH 6960

Query: 6961 DYSCTHSKGKRDRKKRVYDYESERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACV 7020
            DYSCTHSKGKRDRKKRVYDYESERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACV
Sbjct: 6961 DYSCTHSKGKRDRKKRVYDYESERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACV 7020

Query: 7021 PADSLEVIPKTIRWTIPPETLRKRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFH 7080
            PADSLEVIPKTIRWTIPPETLRKRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFH
Sbjct: 7021 PADSLEVIPKTIRWTIPPETLRKRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFH 7080

Query: 7081 S 7081
            S
Sbjct: 7081 S 7081


>gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 8592 bits (22294), Expect = 0.0
 Identities = 4562/5549 (82%), Positives = 4771/5549 (85%), Gaps = 285/5549 (5%)

Query: 55   MKACASFWKKPTLPEKGSSDVQETEDSCPKSRKLAPENWSVINSSSGERVGTFL------ 108
            MKACASFWKKPTLPEKGSSDVQE +                       R+G  L      
Sbjct: 1    MKACASFWKKPTLPEKGSSDVQELQ-----------------------RIGQLLIHLQEK 37

Query: 109  EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF 168
            EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF
Sbjct: 38   EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF 97

Query: 169  YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED 228
            YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED
Sbjct: 98   YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED 157

Query: 229  LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG 288
            LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG
Sbjct: 158  LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG 217

Query: 289  MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK 348
            MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK
Sbjct: 218  MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK 277

Query: 349  KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK 408
            KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK
Sbjct: 278  KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK 337

Query: 409  YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL 468
            YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL
Sbjct: 338  YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL 397

Query: 469  STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK 528
            STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK
Sbjct: 398  STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK 457

Query: 529  ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI 588
            ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI
Sbjct: 458  ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI 517

Query: 589  NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN 648
            NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN
Sbjct: 518  NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN 577

Query: 649  GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME 708
            GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME
Sbjct: 578  GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME 637

Query: 709  SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 768
            SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG
Sbjct: 638  SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 697

Query: 769  LLISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI 828
            LLISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI
Sbjct: 698  LLISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI 757

Query: 829  TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE 888
            TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE
Sbjct: 758  TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE 817

Query: 889  TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS 948
            TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS
Sbjct: 818  TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS 877

Query: 949  SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP 1008
            SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP
Sbjct: 878  SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP 937

Query: 1009 ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF 1068
            ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF
Sbjct: 938  ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF 997

Query: 1069 KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL 1128
            KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL
Sbjct: 998  KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL 1057

Query: 1129 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN 1188
            QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN
Sbjct: 1058 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN 1117

Query: 1189 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE 1248
            ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE
Sbjct: 1118 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE 1177

Query: 1249 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS 1308
            SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS
Sbjct: 1178 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS 1237

Query: 1309 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN 1368
            DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN
Sbjct: 1238 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN 1297

Query: 1369 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1428
            TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL
Sbjct: 1298 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1357

Query: 1429 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ 1488
            PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ
Sbjct: 1358 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ 1417

Query: 1489 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND 1548
            MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND
Sbjct: 1418 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND 1477

Query: 1549 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ 1608
            IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ
Sbjct: 1478 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ 1537

Query: 1609 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG 1668
            TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG
Sbjct: 1538 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG 1597

Query: 1669 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG 1728
            TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG
Sbjct: 1598 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG 1657

Query: 1729 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ 1788
            PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ
Sbjct: 1658 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ 1717

Query: 1789 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHK 1848
            VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHK
Sbjct: 1718 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHK 1777

Query: 1849 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN 1908
            LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN
Sbjct: 1778 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN 1837

Query: 1909 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD 1968
            GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD
Sbjct: 1838 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD 1897

Query: 1969 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE 2028
            MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE
Sbjct: 1898 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE 1957

Query: 2029 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI 2088
            GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI
Sbjct: 1958 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI 2017

Query: 2089 GSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG 2148
            GSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG
Sbjct: 2018 GSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG 2077

Query: 2149 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA 2208
            KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA
Sbjct: 2078 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA 2137

Query: 2209 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF 2268
            TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF
Sbjct: 2138 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF 2197

Query: 2269 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL 2328
            FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL
Sbjct: 2198 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL 2257

Query: 2329 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL 2388
            KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL
Sbjct: 2258 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL 2317

Query: 2389 NPKCLTMKEKKPPISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2448
            NPKCLTMKEKKPPISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT
Sbjct: 2318 NPKCLTMKEKKPPISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2377

Query: 2449 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH 2508
            PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH
Sbjct: 2378 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH 2437

Query: 2509 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK 2568
            DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK
Sbjct: 2438 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK 2497

Query: 2569 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL 2628
            NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL
Sbjct: 2498 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL 2557

Query: 2629 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN 2688
            AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN
Sbjct: 2558 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN 2617

Query: 2689 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2748
            KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR
Sbjct: 2618 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2677

Query: 2749 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA 2808
            ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA
Sbjct: 2678 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA 2737

Query: 2809 KRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV 2868
            KRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV
Sbjct: 2738 KRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV 2797

Query: 2869 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED 2928
            KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED
Sbjct: 2798 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED 2857

Query: 2929 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG 2988
            ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG
Sbjct: 2858 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG 2917

Query: 2989 SKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENT 3048
            SKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENT
Sbjct: 2918 SKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENT 2977

Query: 3049 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP 3108
            GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP
Sbjct: 2978 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP 3037

Query: 3109 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ 3168
            DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ
Sbjct: 3038 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ 3097

Query: 3169 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE 3228
            KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE
Sbjct: 3098 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE 3157

Query: 3229 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA 3288
            KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA
Sbjct: 3158 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA 3217

Query: 3289 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD 3348
            LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD
Sbjct: 3218 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD 3277

Query: 3349 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC 3408
            AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC
Sbjct: 3278 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC 3337

Query: 3409 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM 3468
            PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM
Sbjct: 3338 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM 3397

Query: 3469 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE 3528
            KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE
Sbjct: 3398 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE 3457

Query: 3529 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN 3588
            KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN
Sbjct: 3458 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN 3517

Query: 3589 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS 3648
            TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS
Sbjct: 3518 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS 3577

Query: 3649 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG 3708
            SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG
Sbjct: 3578 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG 3637

Query: 3709 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV 3768
            KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV
Sbjct: 3638 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV 3697

Query: 3769 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKE 3828
            SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKE
Sbjct: 3698 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKE 3757

Query: 3829 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ 3888
            PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ
Sbjct: 3758 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ 3817

Query: 3889 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3948
            QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE
Sbjct: 3818 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3877

Query: 3949 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 4008
            LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE
Sbjct: 3878 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 3937

Query: 4009 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 4068
            SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE
Sbjct: 3938 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 3997

Query: 4069 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4128
            QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA
Sbjct: 3998 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4057

Query: 4129 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4188
            GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL
Sbjct: 4058 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4117

Query: 4189 NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG 4248
            NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG
Sbjct: 4118 NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG 4177

Query: 4249 VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS 4308
            VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS
Sbjct: 4178 VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS 4237

Query: 4309 SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQN 4368
            SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDE K      L  P +  L   +     
Sbjct: 4238 SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYE----- 4292

Query: 4369 LPLNPKEPGKRDGEG----------QEQGKEDGE-------GEEQGNRDGETEEQQ---- 4407
              LN ++ G+ D +G          Q++  + G+       G +  N     +E +    
Sbjct: 4293 --LNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKE 4350

Query: 4408 -------------QADGVGTEQEK-----------RDGHKSKQ----------------- 4426
                         Q +G   E E+             G K+++                 
Sbjct: 4351 VDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKS 4410

Query: 4427 ETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVD 4486
            E  +FL +P   SL+  +L+ R  G+++ QG+ +S        +S D GK+ +T S+  D
Sbjct: 4411 ELDVFLTIP---SLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLND 4467

Query: 4487 SSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREV 4546
             + D     +Y  Q + D+   +S   +M PE    +AE+  L H L        KT+E+
Sbjct: 4468 ITGDSNRT-KYMAQIQKDKA-NISEKSVMHPEYIAVKAEKSPLSHIL--------KTKEL 4517

Query: 4547 LTNIKEKLRHVQERKSELDVFLT-----IPSLSHCKLDKRTAGKKEEQG---VTRSFLPP 4598
              NI ++    QE + E+ V L+     + S +  +LD      KEE+G   +TRSF+P 
Sbjct: 4518 QVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELD----SIKEEEGEPRITRSFMP- 4572

Query: 4599 SWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKA--- 4655
              H+E  ++   + T       +      + + Q +     +S   +MHP     KA   
Sbjct: 4573 --HLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTS 4630

Query: 4656 ---------EKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLEL 4706
                     E SPLS   K KE Q  + ++  + Q+      V+L+KT PF        +
Sbjct: 4631 APPQVFSITEHSPLS---KRKEPQWGMKERAGQKQDRTGRPHVILTKTHPF--------M 4679

Query: 4707 DSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTK---PTESLVKKEKQLLPQKE--DRV 4761
             S+      P       P L I       + A +     +  ++ K  Q +P KE  DRV
Sbjct: 4680 PSLSHHRFSPS-----QPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRV 4734

Query: 4762 QTVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPH 4821
            +     G + P     +A+  A P          L   K     ++E+    Q+    P 
Sbjct: 4735 KIEGREGRILPKRIHLRAE--ALPLAL-------LCNGKNYSLHIEEQGEGVQESKKEPG 4785

Query: 4822 VILTKTHPFMP----------------SLSHHRFSPSQPKLPISSGAGKSRLANSNEG-- 4863
            V+  K+  F P                +L   +FS    K+  SS +GK     S  G  
Sbjct: 4786 VVPRKSASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYT 4845

Query: 4864 ISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIE 4923
            +S+ K  ++   Q    E K  ++I+  E ++LPK   L+A+ L L+ + N K      +
Sbjct: 4846 LSNSKGPVQPTAQ---GEEKGGLRID-MEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSK 4901

Query: 4924 EQGEGVQESK-KEPGVVPRKSASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSS 4982
            EQ   +QE K K+   +P  + S   PP YL  DT   + E  +   + S P  + ++SS
Sbjct: 4902 EQKRKIQEDKNKQVKGLPSINTSLLTPP-YLKFDTTEGQ-ENVIRIAKVSLPQSRSKESS 4959

Query: 4983 DSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRI-DMEDKMLPKCTDLKAKQLLLSD 5041
            D+G+ A  E+ HG   S+ K       Q EEK   ++ DM   + P    LKAK+  +  
Sbjct: 4960 DAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLH 5019

Query: 5042 ILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSI----NTSLLTPPYLKFDTTEGQENVIRI 5097
              +   LQWK++EQ    +E+K ++VK  P +    + S  +P +L  +T   +E++  +
Sbjct: 5020 THSFSDLQWKTREQ----EEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPIL 5075

Query: 5098 AKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDP 5157
             + S P  + + S D     C     G++   +++ K H+ Q +E+D  ++  +  ++ P
Sbjct: 5076 TRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGK-HVSQNKEEDDVQIVSI--LIFP 5132

Query: 5158 NKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPS--RSSPLHLNV 5215
                                      + +EEKVQ+ +  PGV+L+KS S    S L L+ 
Sbjct: 5133 --------------------------KHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDK 5166

Query: 5216 NTGFQEESI----PILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVSQNKE 5271
             T    E +    PIL R S       +       + +  I  D+     + +H+ Q +E
Sbjct: 5167 ETHLGNEMLRLKRPILRRIS------HIGETVHRESVVGDIPKDV---KNEKQHIPQKEE 5217

Query: 5272 EDDVQIV-----SILIFPK--------HQEE--------KVQECEGE---PGVVLTKST- 5306
             +  +I+      I +  K        H+ E          +E EG+   PG++  K   
Sbjct: 5218 RNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCI 5277

Query: 5307 --SLPSLSQLELDKETHLGNEMLRLKRPIL-----RRISHIGETVHRESVVGDIPKDVKN 5359
              S P  S L+L++ TH   E L  K   +       +    +T   E+  GD+ K    
Sbjct: 5278 LFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKG--- 5334

Query: 5360 EKQHIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKP 5419
             K H  QKE R++ K IDMR      +++ SP S +L+  EL +NI    +K H+ +D+ 
Sbjct: 5335 -KPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEA 5393

Query: 5420 PGMIQRKMCILFSKP---LPSNLKLERAT 5445
              ++ R    + S P   L S  K ++ T
Sbjct: 5394 CVVLSRTFLSIPSAPPLYLDSGNKTDKDT 5422



 Score = 5486 bits (14230), Expect = 0.0
 Identities = 2909/3639 (79%), Positives = 3054/3639 (83%), Gaps = 274/3639 (7%)

Query: 3655 KQHISQGKN--DRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQE 3712
            K+ +S+G N   R   +D+      + I K R   +  ++S ++        KQ+  +  
Sbjct: 3353 KEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMK------KQDSMLPL 3406

Query: 3713 GKGKSSMKLTNLC----------TSLPSLSHSNSNSRTKAGKDKSGTLKG--------CL 3754
            G    ++K  +L             +  L  +NS+ + + GK K  T K         CL
Sbjct: 3407 GSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGK-KIETQKANEKVQKEVCL 3465

Query: 3755 PPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLK 3814
            P + L + S +  +       +DS+  VI       K++                  T K
Sbjct: 3466 P-ITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRR------------------TSK 3506

Query: 3815 GKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNV---------VQNKLCASILSPPHLE 3865
             KKS+F H+L+  +   S+ +LE      +  +NV         V  K+C SILS PH +
Sbjct: 3507 WKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFK 3566

Query: 3866 WNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKA--KHMPQKDKDRV 3923
             N                               ++ ID  +SS  K+  +H+ Q   DRV
Sbjct: 3567 LN-------------------------------KETIDGVISSNVKSTKQHISQGKNDRV 3595

Query: 3924 EKALEKIMHSKRIALEVKQPSIFQELE-------LNIKEKGGKIQEDKEVEIWSKPFASI 3976
            +    K + S  I L+ ++ S+   L        L+I ++ GK+QE K            
Sbjct: 3596 KAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCT 3655

Query: 3977 SFLPYSKVGTIEGEEAMRIK---MRSSFSQPNLQESSDTEKTAYEKCIS-DNISNSVKKA 4032
            S    S   +    +A + K   ++       LQ SS+  + +  + I+ D++SN ++  
Sbjct: 3656 SLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESK 3715

Query: 4033 LESILQKEQRQKMEKIRALKKMKSSISQGI-------------QLDIKEQEKRIEHIKGE 4079
                 +KE R+ +  ++ +  +K    +G              Q   K+ EK  +  +  
Sbjct: 3716 CFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESN 3775

Query: 4080 PSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKG 4139
             +V+    CASI SP HL+ + R ++  Y+  ITR+ L   + Q+ S+  EK +      
Sbjct: 3776 LNVVQNKLCASILSPPHLEWNPRIKEV-YMRGITRFCLSSSTQQELSDTMEKCEQPID-- 3832

Query: 4140 DITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKK-ALSQDLPLNTKEPGKMDQ 4198
            D    ++KAK +M QK+ D V+ + +K IMH +   L+ K+ ++ Q+L LN KE G   Q
Sbjct: 3833 DSLSSIEKAK-HMPQKDKDRVEKALEK-IMHSKRIALEVKQPSIFQELELNIKEKGGKIQ 3890

Query: 4199 EAQEQGKEDR----------------EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEV-- 4240
            E +E     +                EGEE  +   R +  +   +E  +  K  +E   
Sbjct: 3891 EDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCI 3950

Query: 4241 ------------------EEQQKADGV--------GIEQGKMDGDKNEQERVLFL----- 4269
                              E++QK + +         I QG     K +++R+  +     
Sbjct: 3951 SDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPS 4010

Query: 4270 YLPSNS-----SLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDS 4324
             L +N+     S +H  LDTR E  E    I R  + +  HQKSSE G+KA+GV S+GD 
Sbjct: 4011 VLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDI 4070

Query: 4325 ASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQ 4384
              +VQKAKDYMQQKE+DEVKISA+KD+MHPEDK LK KKALSQ+LPLN KEPGK D E Q
Sbjct: 4071 TIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQ 4130

Query: 4385 EQG----------------------------------------KEDGEGEEQGNRDGETE 4404
            EQG                                        K DG G EQG  DG+  
Sbjct: 4131 EQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKN 4190

Query: 4405 EQQ-------------------------------------------------QADGVGTE 4415
            EQ+                                                 +A+GV +E
Sbjct: 4191 EQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSE 4250

Query: 4416 -------------QEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA 4462
                          ++++  +SKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA
Sbjct: 4251 GDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA 4310

Query: 4463 TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF 4522
            TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF
Sbjct: 4311 TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF 4370

Query: 4523 EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT 4582
            EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT
Sbjct: 4371 EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT 4430

Query: 4583 AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE 4642
            AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE
Sbjct: 4431 AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE 4490

Query: 4643 KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA 4702
            KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA
Sbjct: 4491 KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA 4550

Query: 4703 FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ 4762
            FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ
Sbjct: 4551 FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ 4610

Query: 4763 TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV 4822
            TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV
Sbjct: 4611 TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV 4670

Query: 4823 ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA 4882
            ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA
Sbjct: 4671 ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA 4730

Query: 4883 KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK 4942
            KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK
Sbjct: 4731 KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK 4790

Query: 4943 SASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK 5002
            SASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK
Sbjct: 4791 SASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK 4850

Query: 5003 GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED 5062
            GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED
Sbjct: 4851 GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED 4910

Query: 5063 KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT 5122
            KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT
Sbjct: 4911 KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT 4970

Query: 5123 HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT 5182
            HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT
Sbjct: 4971 HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT 5030

Query: 5183 REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD 5242
            REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD
Sbjct: 5031 REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD 5090

Query: 5243 TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL 5302
            TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL
Sbjct: 5091 TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL 5150

Query: 5303 TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ 5362
            TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ
Sbjct: 5151 TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ 5210

Query: 5363 HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM 5422
            HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM
Sbjct: 5211 HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM 5270

Query: 5423 IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD 5482
            IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD
Sbjct: 5271 IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD 5330

Query: 5483 VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK 5542
            VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK
Sbjct: 5331 VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK 5390

Query: 5543 DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV 5602
            DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV
Sbjct: 5391 DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV 5450

Query: 5603 EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIY 5662
            EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIY
Sbjct: 5451 EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIY 5510

Query: 5663 FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN 5722
            FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN
Sbjct: 5511 FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN 5570

Query: 5723 HKISPKASVSLIRKISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDK 5782
            HKISPKASVSLIRKISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDK
Sbjct: 5571 HKISPKASVSLIRKISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDK 5630

Query: 5783 PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH 5842
            PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH
Sbjct: 5631 PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH 5690

Query: 5843 GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ 5902
            GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ
Sbjct: 5691 GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ 5750

Query: 5903 ALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN 5962
            ALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN
Sbjct: 5751 ALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN 5810

Query: 5963 QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKT 6022
            QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKT
Sbjct: 5811 QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKT 5870

Query: 6023 QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRL 6082
            QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRL
Sbjct: 5871 QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRL 5930

Query: 6083 TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI 6142
            TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI
Sbjct: 5931 TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI 5990

Query: 6143 FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT 6202
            FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT
Sbjct: 5991 FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT 6050

Query: 6203 VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR 6262
            VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR
Sbjct: 6051 VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR 6110

Query: 6263 IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ 6322
            IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ
Sbjct: 6111 IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ 6170

Query: 6323 VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP 6382
            VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP
Sbjct: 6171 VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP 6230

Query: 6383 PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM 6442
            PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM
Sbjct: 6231 PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM 6290

Query: 6443 FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV 6502
            FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV
Sbjct: 6291 FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV 6350

Query: 6503 SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM 6562
            SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM
Sbjct: 6351 SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM 6410

Query: 6563 KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY 6622
            KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY
Sbjct: 6411 KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY 6470

Query: 6623 LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS 6682
            LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS
Sbjct: 6471 LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS 6530

Query: 6683 PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC 6742
            PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC
Sbjct: 6531 PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC 6590

Query: 6743 ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS 6802
            ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS
Sbjct: 6591 ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS 6650

Query: 6803 YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH 6862
            YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH
Sbjct: 6651 YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH 6710

Query: 6863 KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN 6922
            KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN
Sbjct: 6711 KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN 6770

Query: 6923 IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES 6982
            IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES
Sbjct: 6771 IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES 6830

Query: 6983 ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR 7042
            ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR
Sbjct: 6831 ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR 6890

Query: 7043 KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS 7081
            KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS
Sbjct: 6891 KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929



 Score = 72.0 bits (175), Expect = 2e-11
 Identities = 161/711 (22%), Positives = 286/711 (40%), Gaps = 134/711 (18%)

Query: 3521 IETQKANEKVQKEVCLPITLHSLSASM-PILQESKGQKDSVEQVIRKGVICHKRRTSKWK 3579
            ++ Q +++  +K     +  ++LS S  P+   ++G++    ++  +  +  K    K K
Sbjct: 4824 LKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAK 4883

Query: 3580 KSVFSHILNTSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLN 3639
            + + S ILNT          ++QW   ++   ++   ++       I  S+L+ P+ K +
Sbjct: 4884 QLLLSDILNTK---------KLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFD 4934

Query: 3640 ---------------------KETID-----------GVISSNVKSTKQHISQGKN-DRV 3666
                                 KE+ D           G +SS+VK  K H+ Q +  DR 
Sbjct: 4935 TTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDRE 4994

Query: 3667 KAMDMKRIKSPN-IILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLC 3725
            K  DM  +  PN + LK +KS + H  S  +        ++E K+Q+ K    + L+   
Sbjct: 4995 KVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTRE-QEEEKVQKVKSGPGVMLSK-S 5052

Query: 3726 TSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIES 3785
             S  S  H N N+  +       T +   P +KLQ S +    +    I  D L  + + 
Sbjct: 5053 PSRSSPLHLNVNTGFQEESIPILT-RPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKG 5111

Query: 3786 KCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDES 3845
            K   Q K+ED   IV +                    L+  K         E+  QE E 
Sbjct: 5112 KHVSQNKEEDDVQIVSI--------------------LIFPKHQ-------EEKVQECEG 5144

Query: 3846 NLNVVQNKLCASILSPPHLEWNP---------RIKEVYMRGITRFCLSSSTQQELSDTME 3896
               VV  K   S+ S   LE +          R+K   +R I+           + +T+ 
Sbjct: 5145 EPGVVLTK-STSLPSLSQLELDKETHLGNEMLRLKRPILRRISH----------IGETVH 5193

Query: 3897 KCEQPIDDSLSSIEKAK-HMPQKDKDRVEKALEKIMHSKRIALEVKQPSIF-----QELE 3950
            + E  + D    ++  K H+PQK++   +K ++  M    I L+ K+          EL 
Sbjct: 5194 R-ESVVGDIPKDVKNEKQHIPQKEERNQKKIID--MRGTDITLKSKKSPRSCMLHRTELH 5250

Query: 3951 LNIKEKGGKIQEDKEVE----------IWSKPFASISFLPYSKVGTIEGEEAMRIKMRSS 4000
            +NI  +G K  E ++            ++SKP  S   L  +   T   EE  R+  ++S
Sbjct: 5251 VNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERA---THADEE--RLGGKTS 5305

Query: 4001 FSQPNLQES-SDTEKTAYEKCISDNISNSVKKALESILQKEQRQKME------KIRALKK 4053
            F  P +  +  DTEKTA     ++  S  V+K      QKE R +++      +I   + 
Sbjct: 5306 FVLPLMPSALPDTEKTAD----AEARSGDVRKGKPHRSQKENRHEVKTIDMRFRIHCQEA 5361

Query: 4054 MKSSIS-----QGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEY 4108
              S +S     + + L+I + EK++   K E  V+L+    SIPS   L LD+  +  + 
Sbjct: 5362 RISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKTDKD 5421

Query: 4109 VTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDE 4159
               IT    P+ +    S   +  +  + +G     V++A+ Y+ + E ++
Sbjct: 5422 TPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQ 5472



 Score = 52.8 bits (125), Expect = 1e-05
 Identities = 181/967 (18%), Positives = 356/967 (36%), Gaps = 113/967 (11%)

Query: 5511 QEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKT 5570
            Q  +I+    + N  EL    N  +K++H+ KD + + L    +S    P +   S  + 
Sbjct: 432  QVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLILPYVKNYSRKQL 491

Query: 5571 DKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVD-KNVVKQAEQYVPR--------PE 5621
             K  PG+       +  +   +T+KI     +E     ++ K+ ++Y           P+
Sbjct: 492  VKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDKENKRLKNISPK 551

Query: 5622 AEQQLTSNFMISVQQRNQPSRV-----RSEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPE 5676
               QL  +FM++  Q   P  +     +S+E L   +  ++   I  T F  + S K  +
Sbjct: 552  MLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKG--IGITEFHVLNSKKPFD 609

Query: 5677 WLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRK 5736
                  K    +  ++ +   +S P M++     ++ED +  +N + ++S          
Sbjct: 610  LHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN--------- 660

Query: 5737 ISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKM 5796
              +EL  +  TP   + F        +Q+   ++  EL+                 +  +
Sbjct: 661  -GEELPTS--TPKTQRCFP--RENTQKQKDFLELVLELSN----------------VGLL 699

Query: 5797 FSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFP 5856
             SP     ++   L+ I I  N  +    E + +++            +   NT  +   
Sbjct: 700  ISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITN 759

Query: 5857 LQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTE----IDPAKGGRKQALLISEQEEG 5912
            +   K+ + +       T + L       I     +    I  +    KQ  L  E+E  
Sbjct: 760  MHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQ 819

Query: 5913 VLEFLPKSLFPPWTFQFQSGDLEEKHQTDANT--------NINLEQK----KLEMDN--- 5957
              E++ KS     TF+       ++ + +AN+        +I+L+QK    K +M+    
Sbjct: 820  NAEYIDKSC----TFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISS 875

Query: 5958 -DSTVNQKEGKLKIGTNRALHLQEEKT--EMHKARTANLEKERGR-MDTSSSAHPHLLSL 6013
              S    KE +++  T     + E      M   +   +++   R  D  S+  P     
Sbjct: 876  GSSKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLT 935

Query: 6014 KAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSP 6073
              E   +   +I   E S       +K  ++  A++   +++      L SF +++   P
Sbjct: 936  MPENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLP 995

Query: 6074 KRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKL--EYDVKLKN 6131
              K Q+ +  + + K  LS KY+ MK++   I  M  I   GT ++RKK+   +++ +K 
Sbjct: 996  YFKRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQ 1055

Query: 6132 IASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLT 6191
            I    K  +G+ +  +   +   P+T   + L  E    +   QE+S    E      + 
Sbjct: 1056 ILQ-DKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFIN 1114

Query: 6192 IVKGEQNFTNTVPQD---------PQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQT 6242
                 QN  +   QD         P+    D   +    +++ E     EM++     +T
Sbjct: 1115 EGNESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTET 1174

Query: 6243 KERIVPEHDVSRIIKKPDLRIIEQEEKIL--------KRILTPTECPSMLEDP------- 6287
                + E  VS I++      ++  +K              +P    S++ DP       
Sbjct: 1175 ----IIESVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRES 1230

Query: 6288 KLPKQ-RDQSEPVWDMTTQKVQQQKAFPGTVP-----IPPQVKSSEV--KIVADSTNAEH 6339
             +P    D  E  +    +K +  K  P T P       P +  S+V  K V  +     
Sbjct: 1231 YIPSNGSDTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTST 1290

Query: 6340 LLPICEATKAISESQVKNM-IQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPK 6398
              P C  TKA+  S  + + +       +LD    +K  +      PE  +T+ + ++ +
Sbjct: 1291 AKPKCVNTKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSR 1350

Query: 6399 TQHKSLL 6405
             Q +  L
Sbjct: 1351 LQREFCL 1357



 Score = 52.8 bits (125), Expect = 1e-05
 Identities = 181/967 (18%), Positives = 356/967 (36%), Gaps = 113/967 (11%)

Query: 503  QVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLILPYVKNYSRKQL 562
            Q  +I+    + N  EL    N  +K++H+ KD + + L    +S    P +   S  + 
Sbjct: 5359 QEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKT 5418

Query: 563  VKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDKENKRLKNISPK 622
             K  PG+       +  +   +T+KI     +E     ++ K+ ++Y           P+
Sbjct: 5419 DKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVD-KNVVKQAEQYVPR--------PE 5469

Query: 623  MLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKG--IGITEFHVLNSKKPFD 680
               QL  +FM++  Q   P  +     +S+E L   +  ++   I  T F  + S K  +
Sbjct: 5470 AEQQLTSNFMISVQQRNQPSRV-----RSEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPE 5524

Query: 681  LHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN--------- 731
                  K    +  ++ +   +S P M++     ++ED +  +N + ++S          
Sbjct: 5525 WLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRK 5584

Query: 732  -GEELPTS--TPKTQRCFP--RENTQKQKDFLELVLELSN----------------VGLL 770
              +EL  +  TP   + F        +Q+   ++  EL+                 +  +
Sbjct: 5585 ISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKM 5644

Query: 771  ISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITN 830
             SP     ++   L+ I I  N  +    E + +++            +   NT  +   
Sbjct: 5645 FSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFP 5704

Query: 831  MHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQ 890
            +   K+ + +       T + L       I     +    I  +    KQ  L  E+E  
Sbjct: 5705 LQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTE----IDPAKGGRKQALLISEQEEG 5760

Query: 891  NAEYIDKSC----TFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISS 946
              E++ KS     TF+       ++ + +AN+        +I+L+QK    K +M+    
Sbjct: 5761 VLEFLPKSLFPPWTFQFQSGDLEEKHQTDANT--------NINLEQK----KLEMDN--- 5805

Query: 947  GSSKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLT 1006
              S    KE +++  T     + E      M   +   +++   R  D  S+  P     
Sbjct: 5806 -DSTVNQKEGKLKIGTNRALHLQEEKT--EMHKARTANLEKERGR-MDTSSSAHPHLLSL 5861

Query: 1007 MPENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLP 1066
              E   +   +I   E S       +K  ++  A++   +++      L SF +++   P
Sbjct: 5862 KAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSP 5921

Query: 1067 YFKRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQ 1126
              K Q+ +  + + K  LS KY+ MK++   I  M  I   GT ++RKK+   +++ +K 
Sbjct: 5922 KRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKL--EYDVKLKN 5979

Query: 1127 ILQ-DKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFIN 1185
            I    K  +G+ +  +   +   P+T   + L  E    +   QE+S    E      + 
Sbjct: 5980 IASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLT 6039

Query: 1186 EGNESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTET 1245
                 QN  +   QD         P+    D   +    +++ E     EM++     +T
Sbjct: 6040 IVKGEQNFTNTVPQD---------PQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQT 6090

Query: 1246 ----IIESVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRES 1301
                + E  VS I++      ++  +K              +P    S++ DP       
Sbjct: 6091 KERIVPEHDVSRIIKKPDLRIIEQEEKIL--------KRILTPTECPSMLEDP------- 6135

Query: 1302 YIPSNGSDTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTST 1361
             +P    D  E  +    +K +  K  P T P       P +  S+V  K V  +     
Sbjct: 6136 KLPKQ-RDQSEPVWDMTTQKVQQQKAFPGTVP-----IPPQVKSSEV--KIVADSTNAEH 6187

Query: 1362 AKPKCVNTKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSR 1421
              P C  TKA+  S  + + +       +LD    +K  +      PE  +T+ + ++ +
Sbjct: 6188 LLPICEATKAISESQVKNM-IQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPK 6246

Query: 1422 LQREFCL 1428
             Q +  L
Sbjct: 6247 TQHKSLL 6253



 Score = 48.5 bits (114), Expect = 2e-04
 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 12/152 (7%)

Query: 6011 LSLKAEESQMKTQVITHRENSRLIMQKQKKELEA-SNAK----------QSIQLQKLFQR 6059
            L++K ++S +      +RE++R   +K K  L+  SN K          +  ++Q+    
Sbjct: 2226 LTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPA 2285

Query: 6060 NVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSN 6119
              L     ++P+    K+Q   + + + K  L+ K LTMK +  PI Q+  I+G+ T  +
Sbjct: 2286 TFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISGQFTTKH 2345

Query: 6120 RKKLEYDVKLKNIASW-SKDVSGIFIRSLSIS 6150
            RKKLE ++K K  A W  ++V+  F  + S +
Sbjct: 2346 RKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2377



 Score = 48.5 bits (114), Expect = 2e-04
 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 12/152 (7%)

Query: 2297 LTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPA 2356
            L++K ++S +      +RE++R   +K K  L+  SN K          +  ++Q+    
Sbjct: 5859 LSLKAEESQMKTQVITHRENSRLIMQKQKKELEA-SNAK----------QSIQLQKLFQR 5907

Query: 2357 TFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISGQFTTKH 2416
              L     ++P+    K+Q   + + + K  L+ K LTMK +  PI Q+  I+G+ T  +
Sbjct: 5908 NVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSN 5967

Query: 2417 RKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2448
            RKKLE ++K K  A W  ++V+  F  + S +
Sbjct: 5968 RKKLEYDVKLKNIASW-SKDVSGIFIRSLSIS 5998



 Score = 40.0 bits (92), Expect = 0.082
 Identities = 117/595 (19%), Positives = 222/595 (37%), Gaps = 92/595 (15%)

Query: 6006 AHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSF 6065
            +H     LK+ E+++   +   RE         +KE      K+   +           F
Sbjct: 1558 SHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAI-----------F 1606

Query: 6066 YSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEY 6125
             S +P     K  +      D+K  ++ K   +K +   I  MLNI     P  RK+L  
Sbjct: 1607 GSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSC 1666

Query: 6126 DV--KLKNIASWSKDVSGIF-IRSLSISIMRSPHTDPKTNLEREKRICLPKF-QEKSPNT 6181
            ++  K+K +    K V   +   +++  I +    + + +  REKR+   +  Q+ SP+ 
Sbjct: 1667 NLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHE 1726

Query: 6182 SEMSKRDTL-TIVKGEQN-------FTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEM 6233
              ++ RD   T+++ E+            +PQ  Q F     Q + L   K E N  S  
Sbjct: 1727 DSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLE-NQGSRK 1785

Query: 6234 NKKYLKAQTKERIVPEHDVSRIIKKPDLRI--------------IEQEEKILKRILT--- 6276
                 K    +++ P   + R   K  L+               ++ E+ +   +LT   
Sbjct: 1786 ILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAI 1845

Query: 6277 ----PTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6332
                PT+   M E     K  +++E   D+    ++ QK+  G        K++   + +
Sbjct: 1846 KRGVPTDRKCMGEQHNSGK-GEKAEFNKDLQATVLELQKSPHG----GEAQKANLTDMES 1900

Query: 6333 DSTNAEHLLPICEATKAISESQVKNMIQDKV----SSDKLDNIQAYKPDDLKS---PPFP 6385
             S+NA ++           +  ++ M+ + V       +    Q   PD  KS   P  P
Sbjct: 1901 GSSNAMNM----NVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSP 1956

Query: 6386 EGPDTISTAIYPKTQHKSLLEQFTPKEKN----KLTSHLES--KALEIQLNLIPEMARKS 6439
            EG     + I  KT+ ++   +   +  +    K + H++   K +E      P+  +  
Sbjct: 1957 EGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSK 2016

Query: 6440 LQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLI 6499
            +        G+I +D  W    R K  + +S    +    N K+      PL  +  +L 
Sbjct: 2017 I--------GSIPRDTPWDENPRRKWDSSIS----EKTAWNQKNLQTVLKPL--DFSSL- 2061

Query: 6500 VDVSSDSEETITKLQSINKLENGTSAVTSASEML--------LPHTLQNHSVKEK 6546
              +SS+ E     L+ I K       VT  ++ L        + ++ +NH  K++
Sbjct: 2062 --MSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQ 2114



 Score = 40.0 bits (92), Expect = 0.082
 Identities = 117/595 (19%), Positives = 222/595 (37%), Gaps = 92/595 (15%)

Query: 1629 SHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAI-----------F 1677
            +H     LK+ E+++   +   RE         +KE      K+   +           F
Sbjct: 5854 AHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSF 5913

Query: 1678 GSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSC 1737
             S +P     K  +      D+K  ++ K   +K +   I  MLNI     P  RK+L  
Sbjct: 5914 YSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEY 5973

Query: 1738 NLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHE 1797
            ++  K+K +    K V   +   +++  I +    + + +  REKR+   +  Q+ SP+ 
Sbjct: 5974 DV--KLKNIASWSKDVSGIF-IRSLSISIMRSPHTDPKTNLEREKRICLPKF-QEKSPNT 6029

Query: 1798 DSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLE-NQGSRK 1856
              ++ RD   T+++ E+            +PQ  Q F     Q + L   K E N  S  
Sbjct: 6030 SEMSKRDTL-TIVKGEQN-------FTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEM 6081

Query: 1857 ILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAI 1916
                 K    +++ P   + R   K  L+               ++ E+ +   +LT   
Sbjct: 6082 NKKYLKAQTKERIVPEHDVSRIIKKPDLRI--------------IEQEEKILKRILT--- 6124

Query: 1917 KRGVPTDRKCMGEQHNSGK-GEKAEFNKDLQATVLELQKSPHG----GEAQKANLTDMES 1971
                PT+   M E     K  +++E   D+    ++ QK+  G        K++   + +
Sbjct: 6125 ----PTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180

Query: 1972 GSSNAMNM----NVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSP 2027
             S+NA ++           +  ++ M+ + V       +    Q   PD  KS   P  P
Sbjct: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKV----SSDKLDNIQAYKPDDLKS---PPFP 6233

Query: 2028 EGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSK 2087
            EG     + I  KT+ ++   +   +  +    K + H++   K +E      P+  +  
Sbjct: 6234 EGPDTISTAIYPKTQHKSLLEQFTPKEKN----KLTSHLES--KALEIQLNLIPEMARKS 6287

Query: 2088 I--------GSIPRDTPWDENPRRKWDSSIS----EKTAWNQKNLQTVLKPL--DFSSL- 2132
            +        G+I +D  W    R K  + +S    +    N K+      PL  +  +L 
Sbjct: 6288 LQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLI 6347

Query: 2133 --MSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQ 2185
              +SS+ E     L+ I K       VT  ++ L        + ++ +NH  K++
Sbjct: 6348 VDVSSDSEETITKLQSINKLENGTSAVTSASEML--------LPHTLQNHSVKEK 6394


>gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 8579 bits (22262), Expect = 0.0
 Identities = 4557/5549 (82%), Positives = 4766/5549 (85%), Gaps = 285/5549 (5%)

Query: 55   MKACASFWKKPTLPEKGSSDVQETEDSCPKSRKLAPENWSVINSSSGERVGTFL------ 108
            MKACASFWKKPTLPEKGSSDVQE +                       R+G  L      
Sbjct: 1    MKACASFWKKPTLPEKGSSDVQELQ-----------------------RIGQLLIHLQEK 37

Query: 109  EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF 168
            EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF
Sbjct: 38   EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF 97

Query: 169  YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED 228
            YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED
Sbjct: 98   YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED 157

Query: 229  LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG 288
            LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG
Sbjct: 158  LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG 217

Query: 289  MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK 348
            MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK
Sbjct: 218  MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK 277

Query: 349  KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK 408
            KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK
Sbjct: 278  KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK 337

Query: 409  YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL 468
            YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL
Sbjct: 338  YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL 397

Query: 469  STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK 528
            STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK
Sbjct: 398  STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK 457

Query: 529  ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI 588
            ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI
Sbjct: 458  ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI 517

Query: 589  NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN 648
            NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN
Sbjct: 518  NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN 577

Query: 649  GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME 708
            GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME
Sbjct: 578  GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME 637

Query: 709  SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 768
            SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG
Sbjct: 638  SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 697

Query: 769  LLISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI 828
            LLIS GSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI
Sbjct: 698  LLISLGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI 757

Query: 829  TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE 888
            TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE
Sbjct: 758  TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE 817

Query: 889  TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS 948
            TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS
Sbjct: 818  TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS 877

Query: 949  SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP 1008
            SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP
Sbjct: 878  SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP 937

Query: 1009 ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF 1068
            ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF
Sbjct: 938  ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF 997

Query: 1069 KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL 1128
            KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL
Sbjct: 998  KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL 1057

Query: 1129 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN 1188
            QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN
Sbjct: 1058 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN 1117

Query: 1189 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE 1248
            ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE
Sbjct: 1118 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE 1177

Query: 1249 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS 1308
            SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS
Sbjct: 1178 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS 1237

Query: 1309 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN 1368
            DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN
Sbjct: 1238 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN 1297

Query: 1369 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1428
            TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL
Sbjct: 1298 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1357

Query: 1429 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ 1488
            PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ
Sbjct: 1358 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ 1417

Query: 1489 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND 1548
            MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND
Sbjct: 1418 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND 1477

Query: 1549 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ 1608
            IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ
Sbjct: 1478 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ 1537

Query: 1609 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG 1668
            TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG
Sbjct: 1538 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG 1597

Query: 1669 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG 1728
            TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG
Sbjct: 1598 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG 1657

Query: 1729 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ 1788
            PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ
Sbjct: 1658 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ 1717

Query: 1789 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHK 1848
            VKQDTSPHEDSITSRDIKETLLQDEEQEERKQE LLKVIPQHLQHFMFRSGQGKDLDFHK
Sbjct: 1718 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHK 1777

Query: 1849 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN 1908
            LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN
Sbjct: 1778 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN 1837

Query: 1909 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD 1968
            GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD
Sbjct: 1838 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD 1897

Query: 1969 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE 2028
            MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE
Sbjct: 1898 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE 1957

Query: 2029 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI 2088
            GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI
Sbjct: 1958 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI 2017

Query: 2089 GSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG 2148
            GSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG
Sbjct: 2018 GSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG 2077

Query: 2149 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA 2208
            KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA
Sbjct: 2078 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA 2137

Query: 2209 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF 2268
            TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF
Sbjct: 2138 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF 2197

Query: 2269 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL 2328
            FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL
Sbjct: 2198 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL 2257

Query: 2329 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL 2388
            KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL
Sbjct: 2258 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL 2317

Query: 2389 NPKCLTMKEKKPPISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2448
            NPKCLTMKEKKPPISQIHKIS QFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT
Sbjct: 2318 NPKCLTMKEKKPPISQIHKISRQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2377

Query: 2449 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH 2508
            PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH
Sbjct: 2378 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH 2437

Query: 2509 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK 2568
            DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK
Sbjct: 2438 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK 2497

Query: 2569 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL 2628
            NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL
Sbjct: 2498 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL 2557

Query: 2629 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN 2688
            AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN
Sbjct: 2558 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN 2617

Query: 2689 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2748
            KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR
Sbjct: 2618 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2677

Query: 2749 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA 2808
            ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA
Sbjct: 2678 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA 2737

Query: 2809 KRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV 2868
            KRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV
Sbjct: 2738 KRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV 2797

Query: 2869 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED 2928
            KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED
Sbjct: 2798 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED 2857

Query: 2929 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG 2988
            ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG
Sbjct: 2858 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG 2917

Query: 2989 SKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENT 3048
            SKRLDIPLNSKGQNIFFTELDTSQQK CQEQELLKQEDISMTNLGSMACPIMEPLHLENT
Sbjct: 2918 SKRLDIPLNSKGQNIFFTELDTSQQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENT 2977

Query: 3049 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP 3108
            GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP
Sbjct: 2978 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP 3037

Query: 3109 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ 3168
            DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ
Sbjct: 3038 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ 3097

Query: 3169 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE 3228
            KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE
Sbjct: 3098 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE 3157

Query: 3229 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA 3288
            KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA
Sbjct: 3158 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA 3217

Query: 3289 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD 3348
            LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD
Sbjct: 3218 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD 3277

Query: 3349 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC 3408
            AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC
Sbjct: 3278 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC 3337

Query: 3409 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM 3468
            PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM
Sbjct: 3338 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM 3397

Query: 3469 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE 3528
            KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE
Sbjct: 3398 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE 3457

Query: 3529 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN 3588
            KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN
Sbjct: 3458 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN 3517

Query: 3589 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS 3648
            TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS
Sbjct: 3518 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS 3577

Query: 3649 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG 3708
            SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG
Sbjct: 3578 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG 3637

Query: 3709 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV 3768
            KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV
Sbjct: 3638 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV 3697

Query: 3769 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKE 3828
            SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKD+MGLKCITLKGKKSLFRHLLHGKE
Sbjct: 3698 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKE 3757

Query: 3829 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ 3888
            PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ
Sbjct: 3758 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ 3817

Query: 3889 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3948
            QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE
Sbjct: 3818 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3877

Query: 3949 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 4008
            LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE
Sbjct: 3878 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 3937

Query: 4009 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 4068
            SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE
Sbjct: 3938 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 3997

Query: 4069 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4128
            QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA
Sbjct: 3998 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4057

Query: 4129 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4188
            GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL
Sbjct: 4058 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4117

Query: 4189 NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG 4248
            NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG
Sbjct: 4118 NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG 4177

Query: 4249 VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS 4308
            VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS
Sbjct: 4178 VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS 4237

Query: 4309 SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQN 4368
            SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDE K      L  P +  L   +     
Sbjct: 4238 SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYE----- 4292

Query: 4369 LPLNPKEPGKRDGEG----------QEQGKEDGE-------GEEQGNRDGETEEQQ---- 4407
              LN ++ G+ D +G          Q++  + G+       G +  N     +E +    
Sbjct: 4293 --LNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKE 4350

Query: 4408 -------------QADGVGTEQEK-----------RDGHKSKQ----------------- 4426
                         Q +G   E E+             G K+++                 
Sbjct: 4351 VDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKS 4410

Query: 4427 ETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVD 4486
            E  +FL +P   SL+  +L+ R  G+++ QG+ +S        +S D GK+ +T S+  D
Sbjct: 4411 ELDVFLTIP---SLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLND 4467

Query: 4487 SSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREV 4546
             + D     +Y  Q + D+   +S   +M PE    +AE+  L H L        KT+E+
Sbjct: 4468 ITGDSNRT-KYMAQIQKDKA-NISEKSVMHPEYIAVKAEKSPLSHIL--------KTKEL 4517

Query: 4547 LTNIKEKLRHVQERKSELDVFLT-----IPSLSHCKLDKRTAGKKEEQG---VTRSFLPP 4598
              NI ++    QE + E+ V L+     + S +  +LD      KEE+G   +TRSF+P 
Sbjct: 4518 QVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELD----SIKEEEGEPRITRSFMP- 4572

Query: 4599 SWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKA--- 4655
              H+E  ++   + T       +      + + Q +     +S   +MHP     KA   
Sbjct: 4573 --HLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTS 4630

Query: 4656 ---------EKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLEL 4706
                     E SPLS   K KE Q  + ++  + Q+      V+L+KT PF        +
Sbjct: 4631 APPQVFSITEHSPLS---KRKEPQWGMKERAGQKQDRTGRPHVILTKTHPF--------M 4679

Query: 4707 DSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTK---PTESLVKKEKQLLPQKE--DRV 4761
             S+      P       P L I       + A +     +  ++ K  Q +P KE  DRV
Sbjct: 4680 PSLSHHRFSPS-----QPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRV 4734

Query: 4762 QTVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPH 4821
            +     G + P     +A+  A P          L   K     ++E+    Q+    P 
Sbjct: 4735 KIEGREGRILPKRIHLRAE--ALPLAL-------LCNGKNYSLHIEEQGEGVQESKKEPG 4785

Query: 4822 VILTKTHPFMP----------------SLSHHRFSPSQPKLPISSGAGKSRLANSNEG-- 4863
            V+  K   F P                +L   +FS    K+  SS +GK     S  G  
Sbjct: 4786 VVPRKPASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYT 4845

Query: 4864 ISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIE 4923
            +S+ K  ++   Q    E K  ++I+  E ++LPK   L+A+ L L+ + N K      +
Sbjct: 4846 LSNSKGPVQPTAQ---GEEKGGLRID-MEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSK 4901

Query: 4924 EQGEGVQESK-KEPGVVPRKSASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSS 4982
            EQ   +QE K K+   +P  + S   PP YL  DT   + E  +   + S P  + ++SS
Sbjct: 4902 EQKRKIQEDKNKQVKGLPSINTSLLTPP-YLKFDTTEGQ-ENVIRIAKVSLPQSRSKESS 4959

Query: 4983 DSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRI-DMEDKMLPKCTDLKAKQLLLSD 5041
            D+G+ A  E+ HG   S+ K       Q EEK   ++ DM   + P    LKAK+  +  
Sbjct: 4960 DAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLH 5019

Query: 5042 ILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSI----NTSLLTPPYLKFDTTEGQENVIRI 5097
              +   LQWK++EQ    +E+K ++VK  P +    + S  +P +L  +T   +E++  +
Sbjct: 5020 THSFSDLQWKTREQ----EEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPIL 5075

Query: 5098 AKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDP 5157
             + S P  + + S D     C     G++   +++ K H+ Q +E+D  ++  +  ++ P
Sbjct: 5076 TRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGK-HVSQNKEEDDVQIVSI--LIFP 5132

Query: 5158 NKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPS--RSSPLHLNV 5215
                                      + +EEKVQ+ +  PGV+L+KS S    S L L+ 
Sbjct: 5133 --------------------------KHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDK 5166

Query: 5216 NTGFQEESI----PILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVSQNKE 5271
             T    E +    PIL R S       +       + +  I  D+     + +H+ Q +E
Sbjct: 5167 ETHLGNEMLRLKRPILRRIS------HIGETVHRESVVGDIPKDV---KNEKQHIPQKEE 5217

Query: 5272 EDDVQIV-----SILIFPK--------HQEE--------KVQECEGE---PGVVLTKST- 5306
             +  +I+      I +  K        H+ E          +E EG+   PG++  K   
Sbjct: 5218 RNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCI 5277

Query: 5307 --SLPSLSQLELDKETHLGNEMLRLKRPIL-----RRISHIGETVHRESVVGDIPKDVKN 5359
              S P  S L+L++ TH   E L  K   +       +    +T   E+  GD+ K    
Sbjct: 5278 LFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKG--- 5334

Query: 5360 EKQHIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKP 5419
             K H  QKE R++ K IDMR      +++ SP S +L+  EL +NI    +K H+ +D+ 
Sbjct: 5335 -KPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEA 5393

Query: 5420 PGMIQRKMCILFSKP---LPSNLKLERAT 5445
              ++ R    + S P   L S  K ++ T
Sbjct: 5394 CVVLSRTFLSIPSAPPLYLDSGNKTDKDT 5422



 Score = 5480 bits (14215), Expect = 0.0
 Identities = 2906/3639 (79%), Positives = 3052/3639 (83%), Gaps = 274/3639 (7%)

Query: 3655 KQHISQGKN--DRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQE 3712
            K+ +S+G N   R   +D+      + I K R   +  ++S ++        KQ+  +  
Sbjct: 3353 KEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMK------KQDSMLPL 3406

Query: 3713 GKGKSSMKLTNLC----------TSLPSLSHSNSNSRTKAGKDKSGTLKG--------CL 3754
            G    ++K  +L             +  L  +NS+ + + GK K  T K         CL
Sbjct: 3407 GSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGK-KIETQKANEKVQKEVCL 3465

Query: 3755 PPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLK 3814
            P + L + S +  +       +DS+  VI       K++                  T K
Sbjct: 3466 P-ITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRR------------------TSK 3506

Query: 3815 GKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNV---------VQNKLCASILSPPHLE 3865
             KKS+F H+L+  +   S+ +LE      +  +NV         V  K+C SILS PH +
Sbjct: 3507 WKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFK 3566

Query: 3866 WNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKA--KHMPQKDKDRV 3923
             N                               ++ ID  +SS  K+  +H+ Q   DRV
Sbjct: 3567 LN-------------------------------KETIDGVISSNVKSTKQHISQGKNDRV 3595

Query: 3924 EKALEKIMHSKRIALEVKQPSIFQELE-------LNIKEKGGKIQEDKEVEIWSKPFASI 3976
            +    K + S  I L+ ++ S+   L        L+I ++ GK+QE K            
Sbjct: 3596 KAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCT 3655

Query: 3977 SFLPYSKVGTIEGEEAMRIK---MRSSFSQPNLQESSDTEKTAYEKCIS-DNISNSVKKA 4032
            S    S   +    +A + K   ++       LQ SS+  + +  + I+ D++SN ++  
Sbjct: 3656 SLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESK 3715

Query: 4033 LESILQKEQRQKMEKIRALKKMKSSISQGI-------------QLDIKEQEKRIEHIKGE 4079
                 +KE R+ +  ++ +  +K    +G              Q   K+ EK  +  +  
Sbjct: 3716 CFPQKKKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESN 3775

Query: 4080 PSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKG 4139
             +V+    CASI SP HL+ + R ++  Y+  ITR+ L   + Q+ S+  EK +      
Sbjct: 3776 LNVVQNKLCASILSPPHLEWNPRIKEV-YMRGITRFCLSSSTQQELSDTMEKCEQPID-- 3832

Query: 4140 DITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKK-ALSQDLPLNTKEPGKMDQ 4198
            D    ++KAK +M QK+ D V+ + +K IMH +   L+ K+ ++ Q+L LN KE G   Q
Sbjct: 3833 DSLSSIEKAK-HMPQKDKDRVEKALEK-IMHSKRIALEVKQPSIFQELELNIKEKGGKIQ 3890

Query: 4199 EAQEQGKEDR----------------EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEV-- 4240
            E +E     +                EGEE  +   R +  +   +E  +  K  +E   
Sbjct: 3891 EDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCI 3950

Query: 4241 ------------------EEQQKADGV--------GIEQGKMDGDKNEQERVLFL----- 4269
                              E++QK + +         I QG     K +++R+  +     
Sbjct: 3951 SDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPS 4010

Query: 4270 YLPSNS-----SLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDS 4324
             L +N+     S +H  LDTR E  E    I R  + +  HQKSSE G+KA+GV S+GD 
Sbjct: 4011 VLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDI 4070

Query: 4325 ASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQ 4384
              +VQKAKDYMQQKE+DEVKISA+KD+MHPEDK LK KKALSQ+LPLN KEPGK D E Q
Sbjct: 4071 TIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQ 4130

Query: 4385 EQG----------------------------------------KEDGEGEEQGNRDGETE 4404
            EQG                                        K DG G EQG  DG+  
Sbjct: 4131 EQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKN 4190

Query: 4405 EQQ-------------------------------------------------QADGVGTE 4415
            EQ+                                                 +A+GV +E
Sbjct: 4191 EQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSE 4250

Query: 4416 -------------QEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA 4462
                          ++++  +SKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA
Sbjct: 4251 GDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA 4310

Query: 4463 TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF 4522
            TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF
Sbjct: 4311 TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF 4370

Query: 4523 EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT 4582
            EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT
Sbjct: 4371 EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT 4430

Query: 4583 AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE 4642
            AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE
Sbjct: 4431 AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE 4490

Query: 4643 KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA 4702
            KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA
Sbjct: 4491 KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA 4550

Query: 4703 FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ 4762
            FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ
Sbjct: 4551 FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ 4610

Query: 4763 TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV 4822
            TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV
Sbjct: 4611 TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV 4670

Query: 4823 ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA 4882
            ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA
Sbjct: 4671 ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA 4730

Query: 4883 KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK 4942
            KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK
Sbjct: 4731 KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK 4790

Query: 4943 SASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK 5002
             ASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK
Sbjct: 4791 PASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK 4850

Query: 5003 GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED 5062
            GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED
Sbjct: 4851 GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED 4910

Query: 5063 KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT 5122
            KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT
Sbjct: 4911 KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT 4970

Query: 5123 HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT 5182
            HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT
Sbjct: 4971 HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT 5030

Query: 5183 REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD 5242
            REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD
Sbjct: 5031 REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD 5090

Query: 5243 TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL 5302
            TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL
Sbjct: 5091 TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL 5150

Query: 5303 TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ 5362
            TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ
Sbjct: 5151 TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ 5210

Query: 5363 HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM 5422
            HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM
Sbjct: 5211 HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM 5270

Query: 5423 IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD 5482
            IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD
Sbjct: 5271 IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD 5330

Query: 5483 VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK 5542
            VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK
Sbjct: 5331 VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK 5390

Query: 5543 DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV 5602
            DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV
Sbjct: 5391 DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV 5450

Query: 5603 EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIY 5662
            EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRV SEEDLNQLVLNSRDEDIY
Sbjct: 5451 EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIY 5510

Query: 5663 FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN 5722
            FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN
Sbjct: 5511 FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN 5570

Query: 5723 HKISPKASVSLIRKISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDK 5782
            HKISPKASVSLIRKISKELYVTLGTPA+SKGFSVSERYAHQQETSSKVSPELAGSCKFDK
Sbjct: 5571 HKISPKASVSLIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDK 5630

Query: 5783 PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH 5842
            PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH
Sbjct: 5631 PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH 5690

Query: 5843 GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ 5902
            GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ
Sbjct: 5691 GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ 5750

Query: 5903 ALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN 5962
            ALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN
Sbjct: 5751 ALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN 5810

Query: 5963 QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKT 6022
            QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKT
Sbjct: 5811 QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKT 5870

Query: 6023 QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRL 6082
            QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRL
Sbjct: 5871 QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRL 5930

Query: 6083 TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI 6142
            TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI
Sbjct: 5931 TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI 5990

Query: 6143 FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT 6202
            FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT
Sbjct: 5991 FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT 6050

Query: 6203 VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR 6262
            VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR
Sbjct: 6051 VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR 6110

Query: 6263 IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ 6322
            IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ
Sbjct: 6111 IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ 6170

Query: 6323 VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP 6382
            VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP
Sbjct: 6171 VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP 6230

Query: 6383 PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM 6442
            PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM
Sbjct: 6231 PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM 6290

Query: 6443 FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV 6502
            FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV
Sbjct: 6291 FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV 6350

Query: 6503 SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM 6562
            SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM
Sbjct: 6351 SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM 6410

Query: 6563 KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY 6622
            KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY
Sbjct: 6411 KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY 6470

Query: 6623 LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS 6682
            LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS
Sbjct: 6471 LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS 6530

Query: 6683 PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC 6742
            PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC
Sbjct: 6531 PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC 6590

Query: 6743 ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS 6802
            ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS
Sbjct: 6591 ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS 6650

Query: 6803 YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH 6862
            YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH
Sbjct: 6651 YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH 6710

Query: 6863 KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN 6922
            KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN
Sbjct: 6711 KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN 6770

Query: 6923 IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES 6982
            IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES
Sbjct: 6771 IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES 6830

Query: 6983 ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR 7042
            ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR
Sbjct: 6831 ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR 6890

Query: 7043 KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS 7081
            KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS
Sbjct: 6891 KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929



 Score = 72.0 bits (175), Expect = 2e-11
 Identities = 161/711 (22%), Positives = 286/711 (40%), Gaps = 134/711 (18%)

Query: 3521 IETQKANEKVQKEVCLPITLHSLSASM-PILQESKGQKDSVEQVIRKGVICHKRRTSKWK 3579
            ++ Q +++  +K     +  ++LS S  P+   ++G++    ++  +  +  K    K K
Sbjct: 4824 LKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAK 4883

Query: 3580 KSVFSHILNTSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLN 3639
            + + S ILNT          ++QW   ++   ++   ++       I  S+L+ P+ K +
Sbjct: 4884 QLLLSDILNTK---------KLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFD 4934

Query: 3640 ---------------------KETID-----------GVISSNVKSTKQHISQGKN-DRV 3666
                                 KE+ D           G +SS+VK  K H+ Q +  DR 
Sbjct: 4935 TTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDRE 4994

Query: 3667 KAMDMKRIKSPN-IILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLC 3725
            K  DM  +  PN + LK +KS + H  S  +        ++E K+Q+ K    + L+   
Sbjct: 4995 KVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTRE-QEEEKVQKVKSGPGVMLSK-S 5052

Query: 3726 TSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIES 3785
             S  S  H N N+  +       T +   P +KLQ S +    +    I  D L  + + 
Sbjct: 5053 PSRSSPLHLNVNTGFQEESIPILT-RPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKG 5111

Query: 3786 KCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDES 3845
            K   Q K+ED   IV +                    L+  K         E+  QE E 
Sbjct: 5112 KHVSQNKEEDDVQIVSI--------------------LIFPKHQ-------EEKVQECEG 5144

Query: 3846 NLNVVQNKLCASILSPPHLEWNP---------RIKEVYMRGITRFCLSSSTQQELSDTME 3896
               VV  K   S+ S   LE +          R+K   +R I+           + +T+ 
Sbjct: 5145 EPGVVLTK-STSLPSLSQLELDKETHLGNEMLRLKRPILRRISH----------IGETVH 5193

Query: 3897 KCEQPIDDSLSSIEKAK-HMPQKDKDRVEKALEKIMHSKRIALEVKQPSIF-----QELE 3950
            + E  + D    ++  K H+PQK++   +K ++  M    I L+ K+          EL 
Sbjct: 5194 R-ESVVGDIPKDVKNEKQHIPQKEERNQKKIID--MRGTDITLKSKKSPRSCMLHRTELH 5250

Query: 3951 LNIKEKGGKIQEDKEVE----------IWSKPFASISFLPYSKVGTIEGEEAMRIKMRSS 4000
            +NI  +G K  E ++            ++SKP  S   L  +   T   EE  R+  ++S
Sbjct: 5251 VNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERA---THADEE--RLGGKTS 5305

Query: 4001 FSQPNLQES-SDTEKTAYEKCISDNISNSVKKALESILQKEQRQKME------KIRALKK 4053
            F  P +  +  DTEKTA     ++  S  V+K      QKE R +++      +I   + 
Sbjct: 5306 FVLPLMPSALPDTEKTAD----AEARSGDVRKGKPHRSQKENRHEVKTIDMRFRIHCQEA 5361

Query: 4054 MKSSIS-----QGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEY 4108
              S +S     + + L+I + EK++   K E  V+L+    SIPS   L LD+  +  + 
Sbjct: 5362 RISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKTDKD 5421

Query: 4109 VTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDE 4159
               IT    P+ +    S   +  +  + +G     V++A+ Y+ + E ++
Sbjct: 5422 TPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQ 5472



 Score = 52.4 bits (124), Expect = 2e-05
 Identities = 181/967 (18%), Positives = 356/967 (36%), Gaps = 113/967 (11%)

Query: 503  QVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLILPYVKNYSRKQL 562
            Q  +I+    + N  EL    N  +K++H+ KD + + L    +S    P +   S  + 
Sbjct: 5359 QEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKT 5418

Query: 563  VKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDKENKRLKNISPK 622
             K  PG+       +  +   +T+KI     +E     ++ K+ ++Y           P+
Sbjct: 5419 DKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVD-KNVVKQAEQYVPR--------PE 5469

Query: 623  MLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKG--IGITEFHVLNSKKPFD 680
               QL  +FM++  Q   P  +      S+E L   +  ++   I  T F  + S K  +
Sbjct: 5470 AEQQLTSNFMISVQQRNQPSRVT-----SEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPE 5524

Query: 681  LHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN--------- 731
                  K    +  ++ +   +S P M++     ++ED +  +N + ++S          
Sbjct: 5525 WLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRK 5584

Query: 732  -GEELPTS--TPKTQRCFP--RENTQKQKDFLELVLELSN----------------VGLL 770
              +EL  +  TP + + F        +Q+   ++  EL+                 +  +
Sbjct: 5585 ISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKM 5644

Query: 771  ISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITN 830
             SP     ++   L+ I I  N  +    E + +++            +   NT  +   
Sbjct: 5645 FSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFP 5704

Query: 831  MHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQ 890
            +   K+ + +       T + L       I     +    I  +    KQ  L  E+E  
Sbjct: 5705 LQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTE----IDPAKGGRKQALLISEQEEG 5760

Query: 891  NAEYIDKSC----TFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISS 946
              E++ KS     TF+       ++ + +AN+        +I+L+QK    K +M+    
Sbjct: 5761 VLEFLPKSLFPPWTFQFQSGDLEEKHQTDANT--------NINLEQK----KLEMDN--- 5805

Query: 947  GSSKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLT 1006
              S    KE +++  T     + E      M   +   +++   R  D  S+  P     
Sbjct: 5806 -DSTVNQKEGKLKIGTNRALHLQEEKT--EMHKARTANLEKERGR-MDTSSSAHPHLLSL 5861

Query: 1007 MPENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLP 1066
              E   +   +I   E S       +K  ++  A++   +++      L SF +++   P
Sbjct: 5862 KAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSP 5921

Query: 1067 YFKRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQ 1126
              K Q+ +  + + K  LS KY+ MK++   I  M  I   GT ++RKK+   +++ +K 
Sbjct: 5922 KRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKL--EYDVKLKN 5979

Query: 1127 ILQ-DKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFIN 1185
            I    K  +G+ +  +   +   P+T   + L  E    +   QE+S    E      + 
Sbjct: 5980 IASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLT 6039

Query: 1186 EGNESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTET 1245
                 QN  +   QD         P+    D   +    +++ E     EM++     +T
Sbjct: 6040 IVKGEQNFTNTVPQD---------PQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQT 6090

Query: 1246 ----IIESVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRES 1301
                + E  VS I++      ++  +K              +P    S++ DP       
Sbjct: 6091 KERIVPEHDVSRIIKKPDLRIIEQEEKIL--------KRILTPTECPSMLEDP------- 6135

Query: 1302 YIPSNGSDTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTST 1361
             +P    D  E  +    +K +  K  P T P       P +  S+V  K V  +     
Sbjct: 6136 KLPKQ-RDQSEPVWDMTTQKVQQQKAFPGTVP-----IPPQVKSSEV--KIVADSTNAEH 6187

Query: 1362 AKPKCVNTKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSR 1421
              P C  TKA+  S  + + +       +LD    +K  +      PE  +T+ + ++ +
Sbjct: 6188 LLPICEATKAISESQVKNM-IQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPK 6246

Query: 1422 LQREFCL 1428
             Q +  L
Sbjct: 6247 TQHKSLL 6253



 Score = 48.5 bits (114), Expect = 2e-04
 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 12/152 (7%)

Query: 2297 LTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPA 2356
            L++K ++S +      +RE++R   +K K  L+  SN K          +  ++Q+    
Sbjct: 5859 LSLKAEESQMKTQVITHRENSRLIMQKQKKELEA-SNAK----------QSIQLQKLFQR 5907

Query: 2357 TFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISGQFTTKH 2416
              L     ++P+    K+Q   + + + K  L+ K LTMK +  PI Q+  I+G+ T  +
Sbjct: 5908 NVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSN 5967

Query: 2417 RKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2448
            RKKLE ++K K  A W  ++V+  F  + S +
Sbjct: 5968 RKKLEYDVKLKNIASW-SKDVSGIFIRSLSIS 5998



 Score = 45.4 bits (106), Expect = 0.002
 Identities = 41/152 (26%), Positives = 75/152 (49%), Gaps = 12/152 (7%)

Query: 6011 LSLKAEESQMKTQVITHRENSRLIMQKQKKELEA-SNAK----------QSIQLQKLFQR 6059
            L++K ++S +      +RE++R   +K K  L+  SN K          +  ++Q+    
Sbjct: 2226 LTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPA 2285

Query: 6060 NVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSN 6119
              L     ++P+    K+Q   + + + K  L+ K LTMK +  PI Q+  I+ + T  +
Sbjct: 2286 TFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQFTTKH 2345

Query: 6120 RKKLEYDVKLKNIASW-SKDVSGIFIRSLSIS 6150
            RKKLE ++K K  A W  ++V+  F  + S +
Sbjct: 2346 RKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2377



 Score = 44.3 bits (103), Expect = 0.004
 Identities = 81/402 (20%), Positives = 155/402 (38%), Gaps = 40/402 (9%)

Query: 6039 KKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTM 6098
            +K  ++  A++   +++      L SF +++   P  K Q+ +  + + K  LS KY+ M
Sbjct: 961  QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM 1020

Query: 6099 KIQNHPIPQMLNITGRGTPSNRKKL--EYDVKLKNIASWSKDVSGIFIRSLSISIMRSPH 6156
            K++   I  M  I   GT ++RKK+   +++ +K I    K  +G+ +  +   +   P+
Sbjct: 1021 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQ-DKIAAGMLLNVIYPPMSILPN 1079

Query: 6157 TDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQD---------P 6207
            T   + L  E    +   QE+S    E      +      QN  +   QD         P
Sbjct: 1080 TRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLP 1139

Query: 6208 QPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQE 6267
            +    D   +    +++ E     EM++     +T    + E  VS I++      ++  
Sbjct: 1140 KAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTET----IIESVVSPIMELSHAENVKST 1195

Query: 6268 EKIL--------KRILTPTECPSMLEDP-------KLPKQ-RDQSEPVWDMTTQKVQQQK 6311
            +K              +P    S++ DP        +P    D  E  +    +K +  K
Sbjct: 1196 QKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPK 1255

Query: 6312 AFPGTVP-----IPPQVKSSEV--KIVADSTNAEHLLPICEATKAISESQVKNM-IQDKV 6363
              P T P       P +  S+V  K V  +       P C  TKA+  S  + + +    
Sbjct: 1256 DLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHR 1315

Query: 6364 SSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLL 6405
               +LD    +K  +      PE  +T+ + ++ + Q +  L
Sbjct: 1316 KKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1357



 Score = 40.0 bits (92), Expect = 0.082
 Identities = 117/595 (19%), Positives = 222/595 (37%), Gaps = 92/595 (15%)

Query: 6006 AHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSF 6065
            +H     LK+ E+++   +   RE         +KE      K+   +           F
Sbjct: 1558 SHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAI-----------F 1606

Query: 6066 YSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEY 6125
             S +P     K  +      D+K  ++ K   +K +   I  MLNI     P  RK+L  
Sbjct: 1607 GSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSC 1666

Query: 6126 DV--KLKNIASWSKDVSGIF-IRSLSISIMRSPHTDPKTNLEREKRICLPKF-QEKSPNT 6181
            ++  K+K +    K V   +   +++  I +    + + +  REKR+   +  Q+ SP+ 
Sbjct: 1667 NLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHE 1726

Query: 6182 SEMSKRDTL-TIVKGEQN-------FTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEM 6233
              ++ RD   T+++ E+            +PQ  Q F     Q + L   K E N  S  
Sbjct: 1727 DSITSRDIKETLLQDEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLE-NQGSRK 1785

Query: 6234 NKKYLKAQTKERIVPEHDVSRIIKKPDLRI--------------IEQEEKILKRILT--- 6276
                 K    +++ P   + R   K  L+               ++ E+ +   +LT   
Sbjct: 1786 ILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAI 1845

Query: 6277 ----PTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6332
                PT+   M E     K  +++E   D+    ++ QK+  G        K++   + +
Sbjct: 1846 KRGVPTDRKCMGEQHNSGK-GEKAEFNKDLQATVLELQKSPHG----GEAQKANLTDMES 1900

Query: 6333 DSTNAEHLLPICEATKAISESQVKNMIQDKV----SSDKLDNIQAYKPDDLKS---PPFP 6385
             S+NA ++           +  ++ M+ + V       +    Q   PD  KS   P  P
Sbjct: 1901 GSSNAMNM----NVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSP 1956

Query: 6386 EGPDTISTAIYPKTQHKSLLEQFTPKEKN----KLTSHLES--KALEIQLNLIPEMARKS 6439
            EG     + I  KT+ ++   +   +  +    K + H++   K +E      P+  +  
Sbjct: 1957 EGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSK 2016

Query: 6440 LQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLI 6499
            +        G+I +D  W    R K  + +S    +    N K+      PL  +  +L 
Sbjct: 2017 I--------GSIPRDTPWDENPRRKWDSSIS----EKTAWNQKNLQTVLKPL--DFSSL- 2061

Query: 6500 VDVSSDSEETITKLQSINKLENGTSAVTSASEML--------LPHTLQNHSVKEK 6546
              +SS+ E     L+ I K       VT  ++ L        + ++ +NH  K++
Sbjct: 2062 --MSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQ 2114



 Score = 40.0 bits (92), Expect = 0.082
 Identities = 117/595 (19%), Positives = 222/595 (37%), Gaps = 92/595 (15%)

Query: 1629 SHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAI-----------F 1677
            +H     LK+ E+++   +   RE         +KE      K+   +           F
Sbjct: 5854 AHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSF 5913

Query: 1678 GSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSC 1737
             S +P     K  +      D+K  ++ K   +K +   I  MLNI     P  RK+L  
Sbjct: 5914 YSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEY 5973

Query: 1738 NLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHE 1797
            ++  K+K +    K V   +   +++  I +    + + +  REKR+   +  Q+ SP+ 
Sbjct: 5974 DV--KLKNIASWSKDVSGIF-IRSLSISIMRSPHTDPKTNLEREKRICLPKF-QEKSPNT 6029

Query: 1798 DSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLE-NQGSRK 1856
              ++ RD   T+++ E+            +PQ  Q F     Q + L   K E N  S  
Sbjct: 6030 SEMSKRDTL-TIVKGEQN-------FTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEM 6081

Query: 1857 ILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAI 1916
                 K    +++ P   + R   K  L+               ++ E+ +   +LT   
Sbjct: 6082 NKKYLKAQTKERIVPEHDVSRIIKKPDLRI--------------IEQEEKILKRILT--- 6124

Query: 1917 KRGVPTDRKCMGEQHNSGK-GEKAEFNKDLQATVLELQKSPHG----GEAQKANLTDMES 1971
                PT+   M E     K  +++E   D+    ++ QK+  G        K++   + +
Sbjct: 6125 ----PTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180

Query: 1972 GSSNAMNM----NVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSP 2027
             S+NA ++           +  ++ M+ + V       +    Q   PD  KS   P  P
Sbjct: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKV----SSDKLDNIQAYKPDDLKS---PPFP 6233

Query: 2028 EGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSK 2087
            EG     + I  KT+ ++   +   +  +    K + H++   K +E      P+  +  
Sbjct: 6234 EGPDTISTAIYPKTQHKSLLEQFTPKEKN----KLTSHLES--KALEIQLNLIPEMARKS 6287

Query: 2088 I--------GSIPRDTPWDENPRRKWDSSIS----EKTAWNQKNLQTVLKPL--DFSSL- 2132
            +        G+I +D  W    R K  + +S    +    N K+      PL  +  +L 
Sbjct: 6288 LQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLI 6347

Query: 2133 --MSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQ 2185
              +SS+ E     L+ I K       VT  ++ L        + ++ +NH  K++
Sbjct: 6348 VDVSSDSEETITKLQSINKLENGTSAVTSASEML--------LPHTLQNHSVKEK 6394



 Score = 33.5 bits (75), Expect = 7.7
 Identities = 84/401 (20%), Positives = 155/401 (38%), Gaps = 57/401 (14%)

Query: 6068 YVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDV 6127
            Y  +SPK    K +    D++  + TK + +K +   + Q+L     GT SN+K+L  ++
Sbjct: 2705 YTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEY---GTASNKKELRGNI 2761

Query: 6128 KLKNIASWSKD-----VSGIFIRSLSISIMRSPHTDPKTNLEREK-RICL---PKFQE-- 6176
            + +     SK+     +  ++     +S ++   T+ K   ++ K R C+   PK ++  
Sbjct: 2762 QQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKK-LTEVKMEKDKPKDRTCILPQPKLEKPL 2820

Query: 6177 KSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLP-NVKSE--------- 6226
            K    S     D  +I++ ++       Q  Q  + D  Q    P  + S+         
Sbjct: 2821 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA 2880

Query: 6227 ANLRSEMNKKYL---KAQTKERIVPEHDVS-----RIIKKPDLRIIEQEEKILKRILTPT 6278
              +R++   ++L   +A+ K+  + +H VS        K+ D+ +  + + I    L  T
Sbjct: 2881 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTEL-DT 2939

Query: 6279 ECPSMLEDPKLPKQRDQS------------EPVWDMTTQKVQQQKAFPGTVPIPPQVKS- 6325
                + ++ +L KQ D S            EP+    T KV +++       I   V   
Sbjct: 2940 SQQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGK 2999

Query: 6326 ---SEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP 6382
                E  I   S   + L    E    +   Q + +  D V    LD+      D L   
Sbjct: 3000 EGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHL- 3058

Query: 6383 PFPEGPDTISTAIYPK-TQHKSLLEQFTPKEKNKLTSHLES 6422
                    ++TA     T  +S  E    KE++KL   L+S
Sbjct: 3059 -----KQAVNTARKENVTISESFNENLWGKEQSKLDITLKS 3094


>gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 8576 bits (22253), Expect = 0.0
 Identities = 4555/5549 (82%), Positives = 4765/5549 (85%), Gaps = 285/5549 (5%)

Query: 55   MKACASFWKKPTLPEKGSSDVQETEDSCPKSRKLAPENWSVINSSSGERVGTFL------ 108
            MKACASFWKKPTLPEKGSSDVQE +                       R+G  L      
Sbjct: 1    MKACASFWKKPTLPEKGSSDVQELQ-----------------------RIGQLLIHLQEK 37

Query: 109  EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF 168
            EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF
Sbjct: 38   EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF 97

Query: 169  YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED 228
            YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED
Sbjct: 98   YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED 157

Query: 229  LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG 288
            LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG
Sbjct: 158  LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG 217

Query: 289  MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK 348
            MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK
Sbjct: 218  MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK 277

Query: 349  KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK 408
            KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK
Sbjct: 278  KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK 337

Query: 409  YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL 468
            YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL
Sbjct: 338  YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL 397

Query: 469  STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK 528
            STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK
Sbjct: 398  STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK 457

Query: 529  ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI 588
            ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI
Sbjct: 458  ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI 517

Query: 589  NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN 648
            NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN
Sbjct: 518  NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN 577

Query: 649  GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME 708
            GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME
Sbjct: 578  GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME 637

Query: 709  SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 768
            SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG
Sbjct: 638  SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 697

Query: 769  LLISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI 828
            LLIS GSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI
Sbjct: 698  LLISLGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI 757

Query: 829  TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE 888
            TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE
Sbjct: 758  TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE 817

Query: 889  TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS 948
            TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS
Sbjct: 818  TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS 877

Query: 949  SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP 1008
            SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP
Sbjct: 878  SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP 937

Query: 1009 ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF 1068
            ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF
Sbjct: 938  ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF 997

Query: 1069 KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL 1128
            KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL
Sbjct: 998  KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL 1057

Query: 1129 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN 1188
            QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN
Sbjct: 1058 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN 1117

Query: 1189 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE 1248
            ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE
Sbjct: 1118 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE 1177

Query: 1249 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS 1308
            SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS
Sbjct: 1178 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS 1237

Query: 1309 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN 1368
            DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN
Sbjct: 1238 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN 1297

Query: 1369 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1428
            TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL
Sbjct: 1298 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1357

Query: 1429 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ 1488
            PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ
Sbjct: 1358 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ 1417

Query: 1489 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND 1548
            MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND
Sbjct: 1418 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND 1477

Query: 1549 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ 1608
            IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ
Sbjct: 1478 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ 1537

Query: 1609 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG 1668
            TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG
Sbjct: 1538 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG 1597

Query: 1669 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG 1728
            TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG
Sbjct: 1598 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG 1657

Query: 1729 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ 1788
            PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ
Sbjct: 1658 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ 1717

Query: 1789 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHK 1848
            VKQDTSPHEDSITSRDIKETLLQDEEQEERKQE LLKVIPQHLQHFMFRSGQGKDLDFHK
Sbjct: 1718 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHK 1777

Query: 1849 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN 1908
            LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN
Sbjct: 1778 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN 1837

Query: 1909 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD 1968
            GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD
Sbjct: 1838 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD 1897

Query: 1969 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE 2028
            MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE
Sbjct: 1898 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE 1957

Query: 2029 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI 2088
            GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI
Sbjct: 1958 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI 2017

Query: 2089 GSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG 2148
            GSIPRDTPWDENPRRKWDSSIS+KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG
Sbjct: 2018 GSIPRDTPWDENPRRKWDSSISQKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG 2077

Query: 2149 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA 2208
            KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA
Sbjct: 2078 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA 2137

Query: 2209 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF 2268
            TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF
Sbjct: 2138 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF 2197

Query: 2269 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL 2328
            FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL
Sbjct: 2198 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL 2257

Query: 2329 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL 2388
            KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL
Sbjct: 2258 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL 2317

Query: 2389 NPKCLTMKEKKPPISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2448
            NPKCLTMKEKKPPISQIHKIS QFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT
Sbjct: 2318 NPKCLTMKEKKPPISQIHKISRQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2377

Query: 2449 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH 2508
            PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH
Sbjct: 2378 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH 2437

Query: 2509 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK 2568
            DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK
Sbjct: 2438 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK 2497

Query: 2569 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL 2628
            NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL
Sbjct: 2498 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL 2557

Query: 2629 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN 2688
            AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN
Sbjct: 2558 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN 2617

Query: 2689 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2748
            KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR
Sbjct: 2618 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2677

Query: 2749 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA 2808
            ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA
Sbjct: 2678 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA 2737

Query: 2809 KRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV 2868
            KRI VSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV
Sbjct: 2738 KRIPVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV 2797

Query: 2869 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED 2928
            KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED
Sbjct: 2798 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED 2857

Query: 2929 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG 2988
            ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG
Sbjct: 2858 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG 2917

Query: 2989 SKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENT 3048
            SKRLDIPLNSKGQNIFFTELDTSQQK CQEQELLKQEDISMTNLGSMACPIMEPLHLENT
Sbjct: 2918 SKRLDIPLNSKGQNIFFTELDTSQQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENT 2977

Query: 3049 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP 3108
            GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP
Sbjct: 2978 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP 3037

Query: 3109 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ 3168
            DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ
Sbjct: 3038 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ 3097

Query: 3169 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE 3228
            KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE
Sbjct: 3098 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE 3157

Query: 3229 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA 3288
            KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA
Sbjct: 3158 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA 3217

Query: 3289 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD 3348
            LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD
Sbjct: 3218 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD 3277

Query: 3349 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC 3408
            AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC
Sbjct: 3278 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC 3337

Query: 3409 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM 3468
            PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM
Sbjct: 3338 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM 3397

Query: 3469 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE 3528
            KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE
Sbjct: 3398 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE 3457

Query: 3529 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN 3588
            KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN
Sbjct: 3458 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN 3517

Query: 3589 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS 3648
            TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS
Sbjct: 3518 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS 3577

Query: 3649 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG 3708
            SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG
Sbjct: 3578 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG 3637

Query: 3709 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV 3768
            KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV
Sbjct: 3638 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV 3697

Query: 3769 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKE 3828
            SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKD+MGLKCITLKGKKSLFRHLLHGKE
Sbjct: 3698 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKE 3757

Query: 3829 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ 3888
            PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ
Sbjct: 3758 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ 3817

Query: 3889 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3948
            QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE
Sbjct: 3818 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3877

Query: 3949 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 4008
            LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE
Sbjct: 3878 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 3937

Query: 4009 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 4068
            SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE
Sbjct: 3938 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 3997

Query: 4069 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4128
            QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA
Sbjct: 3998 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4057

Query: 4129 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4188
            GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL
Sbjct: 4058 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4117

Query: 4189 NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG 4248
            NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG
Sbjct: 4118 NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG 4177

Query: 4249 VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS 4308
            VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS
Sbjct: 4178 VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS 4237

Query: 4309 SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQN 4368
            SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDE K      L  P +  L   +     
Sbjct: 4238 SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYE----- 4292

Query: 4369 LPLNPKEPGKRDGEG----------QEQGKEDGE-------GEEQGNRDGETEEQQ---- 4407
              LN ++ G+ D +G          Q++  + G+       G +  N     +E +    
Sbjct: 4293 --LNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKE 4350

Query: 4408 -------------QADGVGTEQEK-----------RDGHKSKQ----------------- 4426
                         Q +G   E E+             G K+++                 
Sbjct: 4351 VDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKS 4410

Query: 4427 ETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVD 4486
            E  +FL +P   SL+  +L+ R  G+++ QG+ +S        +S D GK+ +T S+  D
Sbjct: 4411 ELDVFLTIP---SLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLND 4467

Query: 4487 SSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREV 4546
             + D     +Y  Q + D+   +S   +M PE    +AE+  L H L        KT+E+
Sbjct: 4468 ITGDSNRT-KYMAQIQKDKA-NISEKSVMHPEYIAVKAEKSPLSHIL--------KTKEL 4517

Query: 4547 LTNIKEKLRHVQERKSELDVFLT-----IPSLSHCKLDKRTAGKKEEQG---VTRSFLPP 4598
              NI ++    QE + E+ V L+     + S +  +LD      KEE+G   +TRSF+P 
Sbjct: 4518 QVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELD----SIKEEEGEPRITRSFMP- 4572

Query: 4599 SWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKA--- 4655
              H+E  ++   + T       +      + + Q +     +S   +MHP     KA   
Sbjct: 4573 --HLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTS 4630

Query: 4656 ---------EKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLEL 4706
                     E SPLS   K KE Q  + ++  + Q+      V+L+KT PF        +
Sbjct: 4631 APPQVFSITEHSPLS---KRKEPQWGMKERAGQKQDRTGRPHVILTKTHPF--------M 4679

Query: 4707 DSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTK---PTESLVKKEKQLLPQKE--DRV 4761
             S+      P       P L I       + A +     +  ++ K  Q +P KE  DRV
Sbjct: 4680 PSLSHHRFSPS-----QPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRV 4734

Query: 4762 QTVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPH 4821
            +     G + P     +A+  A P          L   K     ++E+    Q+    P 
Sbjct: 4735 KIEGREGRILPKRIHLRAE--ALPLAL-------LCNGKNYSLHIEEQGEGVQESKKEPG 4785

Query: 4822 VILTKTHPFMP----------------SLSHHRFSPSQPKLPISSGAGKSRLANSNEG-- 4863
            V+  K   F P                +L   +FS    K+  SS +GK     S  G  
Sbjct: 4786 VVPRKPASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYT 4845

Query: 4864 ISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIE 4923
            +S+ K  ++   Q    E K  ++I+  E ++LPK   L+A+ L L+ + N K      +
Sbjct: 4846 LSNSKGPVQPTAQ---GEEKGGLRID-MEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSK 4901

Query: 4924 EQGEGVQESK-KEPGVVPRKSASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSS 4982
            EQ   +QE K K+   +P  + S   PP YL  DT   + E  +   + S P  + ++SS
Sbjct: 4902 EQKRKIQEDKNKQVKGLPSINTSLLTPP-YLKFDTTEGQ-ENVIRIAKVSLPQSRSKESS 4959

Query: 4983 DSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRI-DMEDKMLPKCTDLKAKQLLLSD 5041
            D+G+ A  E+ HG   S+ K       Q EEK   ++ DM   + P    LKAK+  +  
Sbjct: 4960 DAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLH 5019

Query: 5042 ILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSI----NTSLLTPPYLKFDTTEGQENVIRI 5097
              +   LQWK++EQ    +E+K ++VK  P +    + S  +P +L  +T   +E++  +
Sbjct: 5020 THSFSDLQWKTREQ----EEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPIL 5075

Query: 5098 AKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDP 5157
             + S P  + + S D     C     G++   +++ K H+ Q +E+D  ++  +  ++ P
Sbjct: 5076 TRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGK-HVSQNKEEDDVQIVSI--LIFP 5132

Query: 5158 NKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPS--RSSPLHLNV 5215
                                      + +EEKVQ+ +  PGV+L+KS S    S L L+ 
Sbjct: 5133 --------------------------KHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDK 5166

Query: 5216 NTGFQEESI----PILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVSQNKE 5271
             T    E +    PIL R S       +       + +  I  D+     + +H+ Q +E
Sbjct: 5167 ETHLGNEMLRLKRPILRRIS------HIGETVHRESVVGDIPKDV---KNEKQHIPQKEE 5217

Query: 5272 EDDVQIV-----SILIFPK--------HQEE--------KVQECEGE---PGVVLTKST- 5306
             +  +I+      I +  K        H+ E          +E EG+   PG++  K   
Sbjct: 5218 RNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCI 5277

Query: 5307 --SLPSLSQLELDKETHLGNEMLRLKRPIL-----RRISHIGETVHRESVVGDIPKDVKN 5359
              S P  S L+L++ TH   E L  K   +       +    +T   E+  GD+ K    
Sbjct: 5278 LFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKG--- 5334

Query: 5360 EKQHIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKP 5419
             K H  QKE R++ K IDMR      +++ SP S +L+  EL +NI    +K H+ +D+ 
Sbjct: 5335 -KPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEA 5393

Query: 5420 PGMIQRKMCILFSKP---LPSNLKLERAT 5445
              ++ R    + S P   L S  K ++ T
Sbjct: 5394 CVVLSRTFLSIPSAPPLYLDSGNKTDKDT 5422



 Score = 5472 bits (14194), Expect = 0.0
 Identities = 2903/3639 (79%), Positives = 3049/3639 (83%), Gaps = 274/3639 (7%)

Query: 3655 KQHISQGKN--DRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQE 3712
            K+ +S+G N   R   +D+      + I K R   +  ++S ++        KQ+  +  
Sbjct: 3353 KEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMK------KQDSMLPL 3406

Query: 3713 GKGKSSMKLTNLC----------TSLPSLSHSNSNSRTKAGKDKSGTLKG--------CL 3754
            G    ++K  +L             +  L  +NS+ + + GK K  T K         CL
Sbjct: 3407 GSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGK-KIETQKANEKVQKEVCL 3465

Query: 3755 PPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLK 3814
            P + L + S +  +       +DS+  VI       K++                  T K
Sbjct: 3466 P-ITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRR------------------TSK 3506

Query: 3815 GKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNV---------VQNKLCASILSPPHLE 3865
             KKS+F H+L+  +   S+ +LE      +  +NV         V  K+C SILS PH +
Sbjct: 3507 WKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFK 3566

Query: 3866 WNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKA--KHMPQKDKDRV 3923
             N                               ++ ID  +SS  K+  +H+ Q   DRV
Sbjct: 3567 LN-------------------------------KETIDGVISSNVKSTKQHISQGKNDRV 3595

Query: 3924 EKALEKIMHSKRIALEVKQPSIFQELE-------LNIKEKGGKIQEDKEVEIWSKPFASI 3976
            +    K + S  I L+ ++ S+   L        L+I ++ GK+QE K            
Sbjct: 3596 KAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCT 3655

Query: 3977 SFLPYSKVGTIEGEEAMRIK---MRSSFSQPNLQESSDTEKTAYEKCIS-DNISNSVKKA 4032
            S    S   +    +A + K   ++       LQ SS+  + +  + I+ D++SN ++  
Sbjct: 3656 SLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESK 3715

Query: 4033 LESILQKEQRQKMEKIRALKKMKSSISQGI-------------QLDIKEQEKRIEHIKGE 4079
                 +KE R+ +  ++ +  +K    +G              Q   K+ EK  +  +  
Sbjct: 3716 CFPQKKKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESN 3775

Query: 4080 PSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKG 4139
             +V+    CASI SP HL+ + R ++  Y+  ITR+ L   + Q+ S+  EK +      
Sbjct: 3776 LNVVQNKLCASILSPPHLEWNPRIKEV-YMRGITRFCLSSSTQQELSDTMEKCEQPID-- 3832

Query: 4140 DITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKK-ALSQDLPLNTKEPGKMDQ 4198
            D    ++KAK +M QK+ D V+ + +K IMH +   L+ K+ ++ Q+L LN KE G   Q
Sbjct: 3833 DSLSSIEKAK-HMPQKDKDRVEKALEK-IMHSKRIALEVKQPSIFQELELNIKEKGGKIQ 3890

Query: 4199 EAQEQGKEDR----------------EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEV-- 4240
            E +E     +                EGEE  +   R +  +   +E  +  K  +E   
Sbjct: 3891 EDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCI 3950

Query: 4241 ------------------EEQQKADGV--------GIEQGKMDGDKNEQERVLFL----- 4269
                              E++QK + +         I QG     K +++R+  +     
Sbjct: 3951 SDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPS 4010

Query: 4270 YLPSNS-----SLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDS 4324
             L +N+     S +H  LDTR E  E    I R  + +  HQKSSE G+KA+GV S+GD 
Sbjct: 4011 VLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDI 4070

Query: 4325 ASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQ 4384
              +VQKAKDYMQQKE+DEVKISA+KD+MHPEDK LK KKALSQ+LPLN KEPGK D E Q
Sbjct: 4071 TIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQ 4130

Query: 4385 EQG----------------------------------------KEDGEGEEQGNRDGETE 4404
            EQG                                        K DG G EQG  DG+  
Sbjct: 4131 EQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKN 4190

Query: 4405 EQQ-------------------------------------------------QADGVGTE 4415
            EQ+                                                 +A+GV +E
Sbjct: 4191 EQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSE 4250

Query: 4416 -------------QEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA 4462
                          ++++  +SKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA
Sbjct: 4251 GDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSA 4310

Query: 4463 TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF 4522
            TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF
Sbjct: 4311 TLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIF 4370

Query: 4523 EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT 4582
            EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT
Sbjct: 4371 EAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRT 4430

Query: 4583 AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE 4642
            AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE
Sbjct: 4431 AGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISE 4490

Query: 4643 KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA 4702
            KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA
Sbjct: 4491 KSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSA 4550

Query: 4703 FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ 4762
            FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ
Sbjct: 4551 FLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQ 4610

Query: 4763 TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV 4822
            TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV
Sbjct: 4611 TVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHV 4670

Query: 4823 ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA 4882
            ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA
Sbjct: 4671 ILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEA 4730

Query: 4883 KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK 4942
            KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK
Sbjct: 4731 KDRVKIEGREGRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK 4790

Query: 4943 SASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK 5002
             ASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK
Sbjct: 4791 PASFPPPPFYLNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSK 4850

Query: 5003 GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED 5062
            GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED
Sbjct: 4851 GPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQED 4910

Query: 5063 KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT 5122
            KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT
Sbjct: 4911 KNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEAT 4970

Query: 5123 HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT 5182
            HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT
Sbjct: 4971 HGELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKT 5030

Query: 5183 REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD 5242
            REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD
Sbjct: 5031 REQEEEKVQKVKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPD 5090

Query: 5243 TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL 5302
            TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL
Sbjct: 5091 TEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVL 5150

Query: 5303 TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ 5362
            TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ
Sbjct: 5151 TKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQ 5210

Query: 5363 HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM 5422
            HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM
Sbjct: 5211 HIPQKEERNQKKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGM 5270

Query: 5423 IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD 5482
            IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD
Sbjct: 5271 IQRKMCILFSKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGD 5330

Query: 5483 VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK 5542
            VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK
Sbjct: 5331 VRKGKPHRSQKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDK 5390

Query: 5543 DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV 5602
            DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV
Sbjct: 5391 DEACVVLSRTFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSV 5450

Query: 5603 EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIY 5662
            EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRV SEEDLNQLVLNSRDEDIY
Sbjct: 5451 EGVDKNVVKQAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIY 5510

Query: 5663 FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN 5722
            FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN
Sbjct: 5511 FTGFGTIRSGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLN 5570

Query: 5723 HKISPKASVSLIRKISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDK 5782
            HKISPKASVSLIRKISKELYVTLGTPA+SKGFSVSERYAHQQETSSKVSPELAGSCKFDK
Sbjct: 5571 HKISPKASVSLIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDK 5630

Query: 5783 PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH 5842
            PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH
Sbjct: 5631 PKEDGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEH 5690

Query: 5843 GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ 5902
            GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ
Sbjct: 5691 GHKTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ 5750

Query: 5903 ALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN 5962
            ALLISEQEEGVLE LPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN
Sbjct: 5751 ALLISEQEEGVLELLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVN 5810

Query: 5963 QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKT 6022
            QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHL SLKAEESQMKT
Sbjct: 5811 QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLPSLKAEESQMKT 5870

Query: 6023 QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRL 6082
            QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPK KDQKGRL
Sbjct: 5871 QVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRL 5930

Query: 6083 TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI 6142
            TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI
Sbjct: 5931 TIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGI 5990

Query: 6143 FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT 6202
            FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT
Sbjct: 5991 FIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNT 6050

Query: 6203 VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR 6262
            VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR
Sbjct: 6051 VPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLR 6110

Query: 6263 IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ 6322
            IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ
Sbjct: 6111 IIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQ 6170

Query: 6323 VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP 6382
            VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP
Sbjct: 6171 VKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP 6230

Query: 6383 PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM 6442
            PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM
Sbjct: 6231 PFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQM 6290

Query: 6443 FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV 6502
            FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV
Sbjct: 6291 FNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDV 6350

Query: 6503 SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM 6562
            SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM
Sbjct: 6351 SSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQM 6410

Query: 6563 KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY 6622
            KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY
Sbjct: 6411 KAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKY 6470

Query: 6623 LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS 6682
            LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS
Sbjct: 6471 LRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQS 6530

Query: 6683 PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC 6742
            PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC
Sbjct: 6531 PHENSSLIRKFPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTC 6590

Query: 6743 ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS 6802
            ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS
Sbjct: 6591 ESVDLRTQRNATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANS 6650

Query: 6803 YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH 6862
            YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH
Sbjct: 6651 YLSQESENILFELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSH 6710

Query: 6863 KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN 6922
            KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN
Sbjct: 6711 KSRKYRSSSKMKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESN 6770

Query: 6923 IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES 6982
            IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES
Sbjct: 6771 IKSHLAKNQGKSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYES 6830

Query: 6983 ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR 7042
            ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR
Sbjct: 6831 ERLDCFQSKHKSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLR 6890

Query: 7043 KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS 7081
            KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS
Sbjct: 6891 KRNFRIPLVAKISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929



 Score = 72.0 bits (175), Expect = 2e-11
 Identities = 161/711 (22%), Positives = 286/711 (40%), Gaps = 134/711 (18%)

Query: 3521 IETQKANEKVQKEVCLPITLHSLSASM-PILQESKGQKDSVEQVIRKGVICHKRRTSKWK 3579
            ++ Q +++  +K     +  ++LS S  P+   ++G++    ++  +  +  K    K K
Sbjct: 4824 LKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLPKCTDLKAK 4883

Query: 3580 KSVFSHILNTSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLN 3639
            + + S ILNT          ++QW   ++   ++   ++       I  S+L+ P+ K +
Sbjct: 4884 QLLLSDILNTK---------KLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFD 4934

Query: 3640 ---------------------KETID-----------GVISSNVKSTKQHISQGKN-DRV 3666
                                 KE+ D           G +SS+VK  K H+ Q +  DR 
Sbjct: 4935 TTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDRE 4994

Query: 3667 KAMDMKRIKSPN-IILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLC 3725
            K  DM  +  PN + LK +KS + H  S  +        ++E K+Q+ K    + L+   
Sbjct: 4995 KVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTRE-QEEEKVQKVKSGPGVMLSK-S 5052

Query: 3726 TSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIES 3785
             S  S  H N N+  +       T +   P +KLQ S +    +    I  D L  + + 
Sbjct: 5053 PSRSSPLHLNVNTGFQEESIPILT-RPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKG 5111

Query: 3786 KCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDES 3845
            K   Q K+ED   IV +                    L+  K         E+  QE E 
Sbjct: 5112 KHVSQNKEEDDVQIVSI--------------------LIFPKHQ-------EEKVQECEG 5144

Query: 3846 NLNVVQNKLCASILSPPHLEWNP---------RIKEVYMRGITRFCLSSSTQQELSDTME 3896
               VV  K   S+ S   LE +          R+K   +R I+           + +T+ 
Sbjct: 5145 EPGVVLTK-STSLPSLSQLELDKETHLGNEMLRLKRPILRRISH----------IGETVH 5193

Query: 3897 KCEQPIDDSLSSIEKAK-HMPQKDKDRVEKALEKIMHSKRIALEVKQPSIF-----QELE 3950
            + E  + D    ++  K H+PQK++   +K ++  M    I L+ K+          EL 
Sbjct: 5194 R-ESVVGDIPKDVKNEKQHIPQKEERNQKKIID--MRGTDITLKSKKSPRSCMLHRTELH 5250

Query: 3951 LNIKEKGGKIQEDKEVE----------IWSKPFASISFLPYSKVGTIEGEEAMRIKMRSS 4000
            +NI  +G K  E ++            ++SKP  S   L  +   T   EE  R+  ++S
Sbjct: 5251 VNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERA---THADEE--RLGGKTS 5305

Query: 4001 FSQPNLQES-SDTEKTAYEKCISDNISNSVKKALESILQKEQRQKME------KIRALKK 4053
            F  P +  +  DTEKTA     ++  S  V+K      QKE R +++      +I   + 
Sbjct: 5306 FVLPLMPSALPDTEKTAD----AEARSGDVRKGKPHRSQKENRHEVKTIDMRFRIHCQEA 5361

Query: 4054 MKSSIS-----QGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEY 4108
              S +S     + + L+I + EK++   K E  V+L+    SIPS   L LD+  +  + 
Sbjct: 5362 RISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKTDKD 5421

Query: 4109 VTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDE 4159
               IT    P+ +    S   +  +  + +G     V++A+ Y+ + E ++
Sbjct: 5422 TPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQ 5472



 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 182/967 (18%), Positives = 356/967 (36%), Gaps = 113/967 (11%)

Query: 503  QVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLILPYVKNYSRKQL 562
            Q  +I+    + N  EL    N  +K++H+ KD + + L    +S    P +   S  + 
Sbjct: 5359 QEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSGNKT 5418

Query: 563  VKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDKENKRLKNISPK 622
             K  PG+       +  +   +T+KI     +E     ++ K+ ++Y           P+
Sbjct: 5419 DKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVD-KNVVKQAEQYVPR--------PE 5469

Query: 623  MLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKG--IGITEFHVLNSKKPFD 680
               QL  +FM++  Q   P  +      S+E L   +  ++   I  T F  + S K  +
Sbjct: 5470 AEQQLTSNFMISVQQRNQPSRVT-----SEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPE 5524

Query: 681  LHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN--------- 731
                  K    +  ++ +   +S P M++     ++ED +  +N + ++S          
Sbjct: 5525 WLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRK 5584

Query: 732  -GEELPTS--TPKTQRCFP--RENTQKQKDFLELVLELSN----------------VGLL 770
              +EL  +  TP + + F        +Q+   ++  EL+                 +  +
Sbjct: 5585 ISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKM 5644

Query: 771  ISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITN 830
             SP     ++   L+ I I  N  +    E + +++            +   NT  +   
Sbjct: 5645 FSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFP 5704

Query: 831  MHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQ 890
            +   K+ + +       T + L       I     +    I  +    KQ  L  E+E  
Sbjct: 5705 LQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTE----IDPAKGGRKQALLISEQEEG 5760

Query: 891  NAEYIDKSC----TFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISS 946
              E + KS     TF+       ++ + +AN+        +I+L+QK    K +M+    
Sbjct: 5761 VLELLPKSLFPPWTFQFQSGDLEEKHQTDANT--------NINLEQK----KLEMDN--- 5805

Query: 947  GSSKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLT 1006
              S    KE +++  T     + E      M   +   +++   R  D  S+  P  P  
Sbjct: 5806 -DSTVNQKEGKLKIGTNRALHLQEEKT--EMHKARTANLEKERGR-MDTSSSAHPHLPSL 5861

Query: 1007 MPENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLP 1066
              E   +   +I   E S       +K  ++  A++   +++      L SF +++   P
Sbjct: 5862 KAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSP 5921

Query: 1067 YFKRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQ 1126
              K Q+ +  + + K  LS KY+ MK++   I  M  I   GT ++RKK+   +++ +K 
Sbjct: 5922 KCKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKL--EYDVKLKN 5979

Query: 1127 ILQ-DKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFIN 1185
            I    K  +G+ +  +   +   P+T   + L  E    +   QE+S    E      + 
Sbjct: 5980 IASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLT 6039

Query: 1186 EGNESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTET 1245
                 QN  +   QD         P+    D   +    +++ E     EM++     +T
Sbjct: 6040 IVKGEQNFTNTVPQD---------PQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQT 6090

Query: 1246 ----IIESVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRES 1301
                + E  VS I++      ++  +K              +P    S++ DP       
Sbjct: 6091 KERIVPEHDVSRIIKKPDLRIIEQEEKIL--------KRILTPTECPSMLEDP------- 6135

Query: 1302 YIPSNGSDTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTST 1361
             +P    D  E  +    +K +  K  P T P       P +  S+V  K V  +     
Sbjct: 6136 KLPKQ-RDQSEPVWDMTTQKVQQQKAFPGTVP-----IPPQVKSSEV--KIVADSTNAEH 6187

Query: 1362 AKPKCVNTKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSR 1421
              P C  TKA+  S  + + +       +LD    +K  +      PE  +T+ + ++ +
Sbjct: 6188 LLPICEATKAISESQVKNM-IQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPK 6246

Query: 1422 LQREFCL 1428
             Q +  L
Sbjct: 6247 TQHKSLL 6253



 Score = 47.0 bits (110), Expect = 7e-04
 Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 12/151 (7%)

Query: 2298 TMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPAT 2357
            ++K ++S +      +RE++R   +K K  L+  SN K          +  ++Q+     
Sbjct: 5860 SLKAEESQMKTQVITHRENSRLIMQKQKKELEA-SNAK----------QSIQLQKLFQRN 5908

Query: 2358 FLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISGQFTTKHR 2417
             L     ++P+    K+Q   + + + K  L+ K LTMK +  PI Q+  I+G+ T  +R
Sbjct: 5909 VLDSFYSYVPLSPKCKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNR 5968

Query: 2418 KKLESNLKTKLKAMWQGENVADTFPNTTSFT 2448
            KKLE ++K K  A W  ++V+  F  + S +
Sbjct: 5969 KKLEYDVKLKNIASW-SKDVSGIFIRSLSIS 5998



 Score = 45.4 bits (106), Expect = 0.002
 Identities = 41/152 (26%), Positives = 75/152 (49%), Gaps = 12/152 (7%)

Query: 6011 LSLKAEESQMKTQVITHRENSRLIMQKQKKELEA-SNAK----------QSIQLQKLFQR 6059
            L++K ++S +      +RE++R   +K K  L+  SN K          +  ++Q+    
Sbjct: 2226 LTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPA 2285

Query: 6060 NVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSN 6119
              L     ++P+    K+Q   + + + K  L+ K LTMK +  PI Q+  I+ + T  +
Sbjct: 2286 TFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQFTTKH 2345

Query: 6120 RKKLEYDVKLKNIASW-SKDVSGIFIRSLSIS 6150
            RKKLE ++K K  A W  ++V+  F  + S +
Sbjct: 2346 RKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2377



 Score = 44.3 bits (103), Expect = 0.004
 Identities = 81/402 (20%), Positives = 155/402 (38%), Gaps = 40/402 (9%)

Query: 6039 KKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTM 6098
            +K  ++  A++   +++      L SF +++   P  K Q+ +  + + K  LS KY+ M
Sbjct: 961  QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM 1020

Query: 6099 KIQNHPIPQMLNITGRGTPSNRKKL--EYDVKLKNIASWSKDVSGIFIRSLSISIMRSPH 6156
            K++   I  M  I   GT ++RKK+   +++ +K I    K  +G+ +  +   +   P+
Sbjct: 1021 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQ-DKIAAGMLLNVIYPPMSILPN 1079

Query: 6157 TDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQD---------P 6207
            T   + L  E    +   QE+S    E      +      QN  +   QD         P
Sbjct: 1080 TRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLP 1139

Query: 6208 QPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQE 6267
            +    D   +    +++ E     EM++     +T    + E  VS I++      ++  
Sbjct: 1140 KAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTET----IIESVVSPIMELSHAENVKST 1195

Query: 6268 EKIL--------KRILTPTECPSMLEDP-------KLPKQ-RDQSEPVWDMTTQKVQQQK 6311
            +K              +P    S++ DP        +P    D  E  +    +K +  K
Sbjct: 1196 QKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPK 1255

Query: 6312 AFPGTVP-----IPPQVKSSEV--KIVADSTNAEHLLPICEATKAISESQVKNM-IQDKV 6363
              P T P       P +  S+V  K V  +       P C  TKA+  S  + + +    
Sbjct: 1256 DLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHR 1315

Query: 6364 SSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLL 6405
               +LD    +K  +      PE  +T+ + ++ + Q +  L
Sbjct: 1316 KKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1357



 Score = 40.0 bits (92), Expect = 0.082
 Identities = 116/601 (19%), Positives = 222/601 (36%), Gaps = 104/601 (17%)

Query: 6006 AHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSF 6065
            +H     LK+ E+++   +   RE         +KE      K+   +           F
Sbjct: 1558 SHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAI-----------F 1606

Query: 6066 YSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEY 6125
             S +P     K  +      D+K  ++ K   +K +   I  MLNI     P  RK+L  
Sbjct: 1607 GSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSC 1666

Query: 6126 DV--KLKNIASWSKDVSGIF-IRSLSISIMRSPHTDPKTNLEREKRICLPKF-QEKSPNT 6181
            ++  K+K +    K V   +   +++  I +    + + +  REKR+   +  Q+ SP+ 
Sbjct: 1667 NLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHE 1726

Query: 6182 SEMSKRDTL-TIVKGEQN-------FTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEM 6233
              ++ RD   T+++ E+            +PQ  Q F     Q + L   K E N  S  
Sbjct: 1727 DSITSRDIKETLLQDEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLE-NQGSRK 1785

Query: 6234 NKKYLKAQTKERIVPEHDVSRIIKKPDLRI--------------IEQEEKILKRILT--- 6276
                 K    +++ P   + R   K  L+               ++ E+ +   +LT   
Sbjct: 1786 ILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAI 1845

Query: 6277 ----PTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6332
                PT+   M E     K  +++E   D+    ++ QK+  G        K++   + +
Sbjct: 1846 KRGVPTDRKCMGEQHNSGK-GEKAEFNKDLQATVLELQKSPHG----GEAQKANLTDMES 1900

Query: 6333 DSTNAEHLLPICEATKAISESQVKNMIQDKV----SSDKLDNIQAYKPDDLKS---PPFP 6385
             S+NA ++           +  ++ M+ + V       +    Q   PD  KS   P  P
Sbjct: 1901 GSSNAMNM----NVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSP 1956

Query: 6386 EGPDTISTAIYPKTQHKSLLEQFTPKEKN----KLTSHLES--KALEIQLNLIPEMARKS 6439
            EG     + I  KT+ ++   +   +  +    K + H++   K +E      P+  +  
Sbjct: 1957 EGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSK 2016

Query: 6440 LQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLI 6499
            +        G+I +D  W    R K  + +S               QK +    N++T++
Sbjct: 2017 I--------GSIPRDTPWDENPRRKWDSSIS---------------QKTAWNQKNLQTVL 2053

Query: 6500 VD------VSSDSEETITKLQSINKLENGTSAVTSASEML--------LPHTLQNHSVKE 6545
                    +SS+ E     L+ I K       VT  ++ L        + ++ +NH  K+
Sbjct: 2054 KPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKK 2113

Query: 6546 K 6546
            +
Sbjct: 2114 Q 2114



 Score = 40.0 bits (92), Expect = 0.082
 Identities = 117/595 (19%), Positives = 222/595 (37%), Gaps = 92/595 (15%)

Query: 1629 SHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAI-----------F 1677
            +H     LK+ E+++   +   RE         +KE      K+   +           F
Sbjct: 5854 AHPHLPSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSF 5913

Query: 1678 GSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSC 1737
             S +P     K  +      D+K  ++ K   +K +   I  MLNI     P  RK+L  
Sbjct: 5914 YSYVPLSPKCKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEY 5973

Query: 1738 NLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHE 1797
            ++  K+K +    K V   +   +++  I +    + + +  REKR+   +  Q+ SP+ 
Sbjct: 5974 DV--KLKNIASWSKDVSGIF-IRSLSISIMRSPHTDPKTNLEREKRICLPKF-QEKSPNT 6029

Query: 1798 DSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLE-NQGSRK 1856
              ++ RD   T+++ E+            +PQ  Q F     Q + L   K E N  S  
Sbjct: 6030 SEMSKRDTL-TIVKGEQN-------FTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEM 6081

Query: 1857 ILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAI 1916
                 K    +++ P   + R   K  L+               ++ E+ +   +LT   
Sbjct: 6082 NKKYLKAQTKERIVPEHDVSRIIKKPDLRI--------------IEQEEKILKRILT--- 6124

Query: 1917 KRGVPTDRKCMGEQHNSGK-GEKAEFNKDLQATVLELQKSPHG----GEAQKANLTDMES 1971
                PT+   M E     K  +++E   D+    ++ QK+  G        K++   + +
Sbjct: 6125 ----PTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180

Query: 1972 GSSNAMNM----NVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSP 2027
             S+NA ++           +  ++ M+ + V       +    Q   PD  KS   P  P
Sbjct: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKV----SSDKLDNIQAYKPDDLKS---PPFP 6233

Query: 2028 EGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSK 2087
            EG     + I  KT+ ++   +   +  +    K + H++   K +E      P+  +  
Sbjct: 6234 EGPDTISTAIYPKTQHKSLLEQFTPKEKN----KLTSHLES--KALEIQLNLIPEMARKS 6287

Query: 2088 I--------GSIPRDTPWDENPRRKWDSSIS----EKTAWNQKNLQTVLKPL--DFSSL- 2132
            +        G+I +D  W    R K  + +S    +    N K+      PL  +  +L 
Sbjct: 6288 LQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLI 6347

Query: 2133 --MSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQ 2185
              +SS+ E     L+ I K       VT  ++ L        + ++ +NH  K++
Sbjct: 6348 VDVSSDSEETITKLQSINKLENGTSAVTSASEML--------LPHTLQNHSVKEK 6394



 Score = 36.6 bits (83), Expect = 0.91
 Identities = 85/401 (21%), Positives = 156/401 (38%), Gaps = 57/401 (14%)

Query: 6068 YVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDV 6127
            Y  +SPK    K +    D++  + TK + +K +  P+ Q+L     GT SN+K+L  ++
Sbjct: 2705 YTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRIPVSQLLEY---GTASNKKELRGNI 2761

Query: 6128 KLKNIASWSKD-----VSGIFIRSLSISIMRSPHTDPKTNLEREK-RICL---PKFQE-- 6176
            + +     SK+     +  ++     +S ++   T+ K   ++ K R C+   PK ++  
Sbjct: 2762 QQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKK-LTEVKMEKDKPKDRTCILPQPKLEKPL 2820

Query: 6177 KSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLP-NVKSE--------- 6226
            K    S     D  +I++ ++       Q  Q  + D  Q    P  + S+         
Sbjct: 2821 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA 2880

Query: 6227 ANLRSEMNKKYL---KAQTKERIVPEHDVS-----RIIKKPDLRIIEQEEKILKRILTPT 6278
              +R++   ++L   +A+ K+  + +H VS        K+ D+ +  + + I    L  T
Sbjct: 2881 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTEL-DT 2939

Query: 6279 ECPSMLEDPKLPKQRDQS------------EPVWDMTTQKVQQQKAFPGTVPIPPQVKS- 6325
                + ++ +L KQ D S            EP+    T KV +++       I   V   
Sbjct: 2940 SQQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGK 2999

Query: 6326 ---SEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSP 6382
                E  I   S   + L    E    +   Q + +  D V    LD+      D L   
Sbjct: 3000 EGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHL- 3058

Query: 6383 PFPEGPDTISTAIYPK-TQHKSLLEQFTPKEKNKLTSHLES 6422
                    ++TA     T  +S  E    KE++KL   L+S
Sbjct: 3059 -----KQAVNTARKENVTISESFNENLWGKEQSKLDITLKS 3094



 Score = 33.5 bits (75), Expect = 7.7
 Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 3/71 (4%)

Query: 2776 YTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEY---GTASNKKELRGNI 2832
            Y  +SPK    K +    D++  + TK + +K +   + Q+L     GT SN+K+L  ++
Sbjct: 5916 YVPLSPKCKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDV 5975

Query: 2833 QQQKSFQLSKN 2843
            + +     SK+
Sbjct: 5976 KLKNIASWSKD 5986


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 84.7 bits (208), Expect = 3e-15
 Identities = 100/431 (23%), Positives = 192/431 (44%), Gaps = 82/431 (19%)

Query: 4040 EQRQKMEKIRALKKMKSSISQGI---------------QLDIKEQEKRIEHIKG----EP 4080
            ++ ++M +++  K  K  +SQGI               +++I E+++  E  KG    E 
Sbjct: 545  DEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQ 604

Query: 4081 SVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGD 4140
             V        +          R+EK E +++       E+S  K+   GE  DG   +GD
Sbjct: 605  EVEANEENVKVHGG-------RKEKTEILSDDLTDKA-EVSEGKAKSVGEAEDGPEGRGD 656

Query: 4141 ITIKV-QKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKA-------KKALSQDLPLNTKE 4192
             T +      ++ Q +E ++ +    +  M    +G K        KK   ++     +E
Sbjct: 657  GTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKERE 716

Query: 4193 PG---KMDQEAQEQGKEDR------EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQ 4243
             G   + +QE +E G+E+       EG+ + +E++ G G+E+ + E+ E G+ + E  E+
Sbjct: 717  QGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE-GEREKEEGER 775

Query: 4244 QKADGVGIEQ-GKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQ-GIIRPGIL 4301
            +K +  G E+ G+ +GD+ E E                  +T   GEE ++ G +  G +
Sbjct: 776  KKEERAGKEEKGEEEGDQGEGEEE----------------ETEGRGEEKEEGGEVEGGEV 819

Query: 4302 QPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKG 4361
            +    +  E  ++  G   EG+   E  +      ++EE E K   E +    E++  +G
Sbjct: 820  EEGKGEREEEEEEGEGEEEEGEGEEEEGEG-----EEEEGEGKGEEEGEEGEGEEEGEEG 874

Query: 4362 KKALSQNLPLNPKEPGKRDGEGQEQGKEDG---EGEEQGNRDGETE-EQQQADGVGTEQ- 4416
            +            E  + +GEG+E+G+ +G   EGE +G  +GE E E+++ +G G E+ 
Sbjct: 875  E---------GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925

Query: 4417 EKRDGHKSKQE 4427
            E+ +G   ++E
Sbjct: 926  EEGEGEGEEEE 936



 Score = 83.6 bits (205), Expect = 6e-15
 Identities = 89/380 (23%), Positives = 168/380 (44%), Gaps = 79/380 (20%)

Query: 4130 EKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLN 4189
            EK +G   K +   K +K ++   Q E +E            E +G   +K    ++   
Sbjct: 769  EKEEGERKKEERAGKEEKGEEEGDQGEGEE-----------EETEGRGEEKEEGGEVEGG 817

Query: 4190 TKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDR----EDKEQGKMDHEVEE--- 4242
              E GK ++E +E+  E  E E +G+E+  G G+E+       E+ E+G+ + E EE   
Sbjct: 818  EVEEGKGEREEEEEEGEGEEEEGEGEEEE-GEGEEEEGEGKGEEEGEEGEGEEEGEEGEG 876

Query: 4243 ---QQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPG 4299
               +++ +G G E+G+ +G++ E E                      EGEE+ +G    G
Sbjct: 877  EGEEEEGEGEGEEEGEGEGEEEEGEG---------------------EGEEEGEG---EG 912

Query: 4300 ILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKE--------------EDEVKI 4345
              +    K  E G++  G   E +   E +  +   +++E              E+E + 
Sbjct: 913  EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972

Query: 4346 SAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETE- 4404
              E+     E+++ +G+    +      +E G+ +GEG+E+G+ +GE EE+G  +GE E 
Sbjct: 973  EGEEGEGEGEEEEGEGEGEEEEG-----EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG 1027

Query: 4405 -------EQQQADGVGTEQEKR-DGHKSKQETVLFLHLPSESSLTCYELNTRKEGEE--- 4453
                   E+++ +  G E+EK  +G ++++          +   T  E N R++GEE   
Sbjct: 1028 EEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKK 1087

Query: 4454 --DLQGIIKSATLQLRQQKS 4471
               ++G +K    +  Q+KS
Sbjct: 1088 VSKIKGSVKYGKHKTYQKKS 1107



 Score = 53.9 bits (128), Expect = 6e-06
 Identities = 82/369 (22%), Positives = 152/369 (41%), Gaps = 34/369 (9%)

Query: 4073 IEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKA 4132
            IE   G  +  L N+     S  +LQ     E+     E   Y L E++  K +E  + +
Sbjct: 431  IEGTLGLSACFLPNSVFPRCSERNLQESVLSEQDLMQPEEPDYLLDEMT--KEAEI-DNS 487

Query: 4133 DGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKE 4192
              V S G+ T  +           +  +K+S  +     + K  +    L+QD  L   +
Sbjct: 488  STVESLGETTDILNMTHIMSLNSNEKSLKLSPVQ-----KQKKQQTIGELTQDTALTEND 542

Query: 4193 PGKMDQEAQE--QGKEDREGEEQGKEDRRGA------GQEKVDREDKEQGKMDHE---VE 4241
                 +E  E  +GK  ++   QG    + A        E+V+  ++++G  D +   +E
Sbjct: 543  DSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIE 602

Query: 4242 EQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGIL 4301
            EQ+       E  K+ G + E+  +L   L   + ++     +  E E+  +G       
Sbjct: 603  EQEVE--ANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEG------- 653

Query: 4302 QPRHQKSSETGKK-ANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLK 4360
              R   + E G   A     E     E  K +  M++  E E ++ AEK+     D + +
Sbjct: 654  --RGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL-AEKEEWKKRDGEEQ 710

Query: 4361 GKKALSQNLPLNPKEPGKRDGEGQ--EQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEK 4418
             +K   Q       +  +  GE +  E  +E+G+ EE+  ++GE +E+ + + V  E+EK
Sbjct: 711  EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770

Query: 4419 RDGHKSKQE 4427
             +G + K+E
Sbjct: 771  EEGERKKEE 779



 Score = 49.7 bits (117), Expect = 1e-04
 Identities = 44/195 (22%), Positives = 85/195 (43%), Gaps = 36/195 (18%)

Query: 4194 GKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQ 4253
            G+ ++E  E   E+ EGEE+G+E+  G  + + + E++E+G+++ EVE ++       E+
Sbjct: 979  GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE 1038

Query: 4254 GKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGK 4313
            G+ +G++ E+E                      EGEE+++          R ++  E GK
Sbjct: 1039 GEEEGEEREKEG---------------------EGEENRRN---------REEEEEEEGK 1068

Query: 4314 KANGVPSEGDSASEVQKAKDYMQ-QKEEDEVKISAEKDLMHPEDKDLKGK-KALSQNLPL 4371
                    G+  +E Q  ++Y +  K +  VK    K        + +G  K     +P+
Sbjct: 1069 ----YQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPV 1124

Query: 4372 NPKEPGKRDGEGQEQ 4386
              K   K    G ++
Sbjct: 1125 QSKRLLKNGPSGSKK 1139



 Score = 48.9 bits (115), Expect = 2e-04
 Identities = 80/372 (21%), Positives = 157/372 (42%), Gaps = 51/372 (13%)

Query: 4079 EPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPE------LSHQKSSEAGEKA 4132
            + SVL          P +L LD   ++AE     T   L E      ++H  S  + EK+
Sbjct: 456  QESVLSEQDLMQPEEPDYL-LDEMTKEAEIDNSSTVESLGETTDILNMTHIMSLNSNEKS 514

Query: 4133 DGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLP--LNT 4190
              ++      ++ QK +  + +   D           + E   +K  KA  Q +   +  
Sbjct: 515  LKLSP-----VQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFM 569

Query: 4191 KEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDH-------EVEEQ 4243
             +P    +   ++  E  E E++G ED +G G E+ + E  E+    H       E+   
Sbjct: 570  TQPATTIEAFSDEEVEIPE-EKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSD 628

Query: 4244 QKADGVGIEQGKM----DGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQG--IIR 4297
               D   + +GK     + +   + R        +S   H+  + R +GE+D+    + R
Sbjct: 629  DLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMER 688

Query: 4298 PGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEED-EVKISAEKDLMHPED 4356
            PG  +    +  E  K+        D   + QK ++   QKE + E++   E++  H E 
Sbjct: 689  PGEGEKELAEKEEWKKR--------DGEEQEQKEREQGHQKERNQEMEEGGEEE--HGEG 738

Query: 4357 KDLKGKKALSQNLPLNPKEPGKRDGEGQEQGK-EDGEGEEQGNRDGETEEQQQADGVGTE 4415
            ++ +G +          +E  +++GEG+E+G+ E+ EGE +   +GE +++++A      
Sbjct: 739  EEEEGDR----------EEEEEKEGEGKEEGEGEEVEGERE-KEEGERKKEERAGKEEKG 787

Query: 4416 QEKRDGHKSKQE 4427
            +E+ D  + ++E
Sbjct: 788  EEEGDQGEGEEE 799


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
            sapiens]
          Length = 916

 Score = 66.2 bits (160), Expect = 1e-09
 Identities = 122/590 (20%), Positives = 251/590 (42%), Gaps = 72/590 (12%)

Query: 3886 STQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSI 3945
            S Q E++      E+ + D L+ I+ A H+  + KD ++  +   +   R  LE      
Sbjct: 226  SLQDEVAFLRSNHEEEVADLLAQIQ-ASHITVERKDYLKTDISTALKEIRSQLESHSDQN 284

Query: 3946 FQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPN 4005
              + E   K +  K+ E  E         +   +  +K    E    ++ K     S   
Sbjct: 285  MHQAEEWFKCRYAKLTEAAE--------QNKEAIRSAKEEIAEYRRQLQSKSIELESVRG 336

Query: 4006 LQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLD 4065
             +ES + + +  E+  + ++S S +  ++ +  + +  K E  R L++ +  ++  + LD
Sbjct: 337  TKESLERQLSDIEERHNHDLS-SYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALD 395

Query: 4066 IKEQEKRIEHIKGEPSVLLTNACASIPSPSH-----LQLDTRREKAEYVT---EITRYYL 4117
            I+    R + ++GE +   T A  SI  P +     + + ++ +K +      ++   ++
Sbjct: 396  IEIAAYR-KLLEGEETRFSTFA-GSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFV 453

Query: 4118 PELSHQ-----KSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPE 4172
             E+  +     + SE  E    +  +  +++K +K +   +++E+ E            E
Sbjct: 454  EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEA-----------E 502

Query: 4173 DKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGA--------GQE 4224
            ++ + AKK+     P+    P   ++E +   KE+ EG+E+ +E+  GA        G E
Sbjct: 503  EEEVAAKKS-----PVKATAPEVKEEEGE---KEEEEGQEEEEEEDEGAKSDQAEEGGSE 554

Query: 4225 KVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDT 4284
            K    +KE+G+ + E E + +A+G   E+ +   +K  +E+         ++    + D 
Sbjct: 555  KEGSSEKEEGEQE-EGETEAEAEG---EEAEAKEEKKVEEK-----SEEVATKEELVADA 605

Query: 4285 RIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEV- 4343
            ++E  E  +    P    P  +K      K+   P E    S V K+   +++K +  V 
Sbjct: 606  KVEKPEKAKS---PVPKSPVEEKGKSPVPKS---PVEEKGKSPVPKSP--VEEKGKSPVP 657

Query: 4344 KISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGE-GQEQGKEDGEGEEQGNRDGE 4402
            K   E+    P  K    +KA S  +P +P E  K   E G+ + KE+ E E +     E
Sbjct: 658  KSPVEEKGKSPVSKSPVEEKAKSP-VPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE 716

Query: 4403 TEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGE 4452
              E+++       ++K+     K+E V  +   ++S     E  T++EG+
Sbjct: 717  KVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGK 766



 Score = 54.7 bits (130), Expect = 3e-06
 Identities = 87/443 (19%), Positives = 180/443 (40%), Gaps = 52/443 (11%)

Query: 3856 ASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHM 3915
            +S +  P +E  P++K V  + +      +  + E S+  E      ++   S+++ K  
Sbjct: 433  SSKIQKPKVE-APKLK-VQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 490

Query: 3916 PQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFAS 3975
              ++K+   +A E+ + +K+  ++   P + +E E   +E+ G+ +E++E E        
Sbjct: 491  AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE-EGEKEEEEGQEEEEEEDE-------- 541

Query: 3976 ISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALES 4035
                      + + EE    K  SS  +   QE  +TE  A  +         V++  E 
Sbjct: 542  -------GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 594

Query: 4036 ILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKR------IEHIKGEP---SVLLTN 4086
            +  KE+     K+   +K KS + +     ++E+ K       +E     P   S +   
Sbjct: 595  VATKEELVADAKVEKPEKAKSPVPKS---PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651

Query: 4087 ACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDIT-IKV 4145
              + +P     +          V E  +  +P+   +++    E   G   + +   +K 
Sbjct: 652  GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 711

Query: 4146 QKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAK-----KALSQDLPLNTKEPGK---MD 4197
               ++ +++KE+    +  KK    P  +   A+     K++   L   TKE GK    +
Sbjct: 712  APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771

Query: 4198 QEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQG--- 4254
            +E ++ G E    EE   +  +G+ +E +    + +GK + E E ++K  G   E+G   
Sbjct: 772  KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831

Query: 4255 ----------KMDGDKNEQERVL 4267
                      K  GDK+E++ V+
Sbjct: 832  NGLDLSPADEKKGGDKSEEKVVV 854



 Score = 47.4 bits (111), Expect = 5e-04
 Identities = 94/441 (21%), Positives = 181/441 (41%), Gaps = 50/441 (11%)

Query: 4030 KKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIK---GEPSVLLTN 4086
            K+A  + L     Q++ ++RA  +M +     +QLD    E+ I  +K    E + L  +
Sbjct: 139  KQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDD 198

Query: 4087 ACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQ 4146
              A+I +      +    K E   ++ +    E++  +S+   E AD +A      I V+
Sbjct: 199  TEAAIRALRKDIEEASLVKVELDKKV-QSLQDEVAFLRSNHEEEVADLLAQIQASHITVE 257

Query: 4147 KAKDYMQQ------KEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEA 4200
            + KDY++       KE      S     MH  ++  K + A   +     KE  +  +E 
Sbjct: 258  R-KDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEE 316

Query: 4201 QEQGKEDREGEEQGKEDRRGAGQEKVDREDKE-QGKMDHEVEEQQKADGVGIEQGKMDGD 4259
              + +   + +    E  RG  +E ++R+  + + + +H++   Q  D +   + ++ G 
Sbjct: 317  IAEYRRQLQSKSIELESVRGT-KESLERQLSDIEERHNHDLSSYQ--DTIQQLENELRGT 373

Query: 4260 KNEQERVLFLY---LPSNSSLTHYILDTR--IEGEEDQQGIIRPGILQPRH--------- 4305
            K E  R L  Y   L    +L   I   R  +EGEE +       I  P +         
Sbjct: 374  KWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITIS 433

Query: 4306 ---QKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEE------DEVKISAEKDLMH--- 4353
               QK      K        +   E  K +D   + EE      +E+ +S +++      
Sbjct: 434  SKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAE 493

Query: 4354 --PEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADG 4411
               E+ + + ++  ++  P+    P  ++ EG+   KE+ EG+E+   + E  +  QA+ 
Sbjct: 494  EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGE---KEEEEGQEEEEEEDEGAKSDQAEE 550

Query: 4412 VGTEQ----EKRDGHKSKQET 4428
             G+E+    EK +G + + ET
Sbjct: 551  GGSEKEGSSEKEEGEQEEGET 571



 Score = 43.9 bits (102), Expect = 0.006
 Identities = 101/538 (18%), Positives = 220/538 (40%), Gaps = 97/538 (18%)

Query: 3991 EAMRIKMRSSFSQPNLQESS-DTEKTAYEKC---ISDNISNSVKKALESILQKEQRQKME 4046
            EA ++K++  F +  ++E+  + EK+  E+    I++ ++ S+K+  +   ++++ +   
Sbjct: 442  EAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEA 501

Query: 4047 KIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKA 4106
            +   +   KS + +    ++KE+E   E  +G+                        E+ 
Sbjct: 502  EEEEVAAKKSPV-KATAPEVKEEEGEKEEEEGQ------------------------EEE 536

Query: 4107 EYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQ--KAKDYMQQKEDDEVKISA 4164
            E   E  +    E    +   + EK +G   +G+   + +  +A+   ++K +++ +  A
Sbjct: 537  EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA 596

Query: 4165 KKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMD---QEAQEQGKED---REGEEQGK--- 4215
             K+ +  + K  K +KA S       +E GK        +E+GK        EE+GK   
Sbjct: 597  TKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 656

Query: 4216 -----EDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLY 4270
                 E++  +   K   E+K +  +     E+ K+     E GK  G++ E+E      
Sbjct: 657  PKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKA---EVGK--GEQKEEEEKEVKE 711

Query: 4271 LPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQK 4330
             P          + ++E +E++   +         +K +E+  K   V    +  +  + 
Sbjct: 712  APK---------EEKVEKKEEKPKDVP-------EKKKAESPVKEEAV---AEVVTITKS 752

Query: 4331 AKDYMQQKEEDEVK-ISAEKDL--------MHPEDKDLKGKKALSQNLPLNPKEPGKRDG 4381
             K +++++ ++E K +  EK+            E  D   K +  +++ +N +  GK + 
Sbjct: 753  VKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEV 812

Query: 4382 EGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLT 4441
            E + + K  G  EE+G      +       +    EK+ G KS+++ V+           
Sbjct: 813  EQETKEKGSGREEEKGVVTNGLD-------LSPADEKKGGDKSEEKVVV---------TK 856

Query: 4442 CYELNTRKEGEEDLQGIIKSATLQLR---QQKSFDAGKIAHTKSFGVDSSNDVKTVQE 4496
              E  T + G+   + I KS T+  +    +++F+   ++  K   V S   VK V +
Sbjct: 857  TVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIVKEVTQ 914



 Score = 39.7 bits (91), Expect = 0.11
 Identities = 103/543 (18%), Positives = 217/543 (39%), Gaps = 82/543 (15%)

Query: 2711 AKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIW 2770
            AK+  A E N E++  +K    +   + + K+ + ++    K      +  E  +S    
Sbjct: 297  AKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTK------ESLERQLSDIEE 350

Query: 2771 SYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEYGTASNKKELRG 2830
             + +  +S    I + +++ +    E   H ++ +     + V   L+   A+ +K L G
Sbjct: 351  RHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQ---DLLNVKMALDIEIAAYRKLLEG 407

Query: 2831 NIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTC----ILPQPK 2886
               +  +F  S      +   +Y     ++   K+ + K+E  K K +      I+ + K
Sbjct: 408  EETRFSTFAGS------ITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETK 461

Query: 2887 LEKPLKEMQRSLSGCTDMSSILRKQE--QDIREKEQKHQSISEDISQYYIGPLRISSQQI 2944
            +E    EM+ +L+  T+  ++  K+E  +   EKE++ ++  E+++     P++ ++ ++
Sbjct: 462  VEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK-SPVKATAPEV 520

Query: 2945 NYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIF 3004
                 +       EE E        E+D G          E  GS++       +G+   
Sbjct: 521  KEEEGEKEEEEGQEEEE--------EEDEGAKSDQA----EEGGSEKEGSSEKEEGEQ-- 566

Query: 3005 FTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKIS 3064
              E +T  +   +E E  +++ +                  E + +V  +E++  + K+ 
Sbjct: 567  -EEGETEAEAEGEEAEAKEEKKVE-----------------EKSEEVATKEELVADAKVE 608

Query: 3065 SHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHK----VPAEQKEQVNPDHVPESILD--S 3118
                 K  + ++   V  KG K     S V+ K    VP    E+     VP+S ++   
Sbjct: 609  KPEKAKSPVPKSP--VEEKG-KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 665

Query: 3119 ESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRM 3178
            +S +SK P+  ++A +   K  V             E++K    +    QK +  K+++ 
Sbjct: 666  KSPVSKSPVE-EKAKSPVPKSPV-------------EEAKSKAEVGKGEQKEEEEKEVKE 711

Query: 3179 KHLSNYYQNKENILESVLPCILHQLYIENP-KKEGSAEEIMSSKVLSPMVEKASHEVGIP 3237
                   + KE   + V      +   E+P K+E  AE +  +K +   +EK + E G P
Sbjct: 712  APKEEKVEKKEEKPKDV----PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 767

Query: 3238 VDQ 3240
            + Q
Sbjct: 768  LQQ 770


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 899

 Score = 65.5 bits (158), Expect = 2e-09
 Identities = 122/660 (18%), Positives = 275/660 (41%), Gaps = 76/660 (11%)

Query: 3792 KKEDR--ENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKM-----TQEDE 3844
            KK DR  E +   +D + L+         L+R+ +  +E ++ N +L++      +++ E
Sbjct: 193  KKADRYIEELTKERDALSLE---------LYRNTITNEELKKKNAELQEKLPLAESEKSE 243

Query: 3845 SNLNV--VQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPI 3902
              LNV  ++ KL  +    P ++ N   +E++ +           ++EL +  +K  +  
Sbjct: 244  IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ-----------EEELREQEKKIRKQE 292

Query: 3903 DDSLSSIEKAKHMPQKDKDRVEKAL--EKIMHSKRIALEVKQPSIFQELELNIKEKGGKI 3960
            +      E+ +    K +++ EK    EK +  +   L  ++  + ++ EL  +E+  + 
Sbjct: 293  EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352

Query: 3961 QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKC 4020
            QE+K   +W                  E EE MR +    + Q       + +    E+ 
Sbjct: 353  QEEK---MW------------------EQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 391

Query: 4021 ISDNISNSVKKALESILQKEQR--------QKMEKIRALKKMKSSISQGIQLDIKEQEKR 4072
            + D      ++  E + +KE+R        +++EK+R  KKM+    +    + K QE+ 
Sbjct: 392  MRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE- 449

Query: 4073 IEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKA 4132
             E I+     +             +Q   ++E+  +  E   +    L  QK  +  E+ 
Sbjct: 450  -ERIREREKKMREEEETMREQEEKMQ---KQEENMWEQEEKEWQQQRLPEQKE-KLWEQE 504

Query: 4133 DGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKE 4192
                 +  I  + +K +D  ++    E K+  ++ +   ED+  + ++ +         +
Sbjct: 505  KMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563

Query: 4193 PGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKE-----QGKMDHEVEEQQKAD 4247
              +M+++ QEQ K+  + EE+ +E+ R   +EK  RE++E     + KM  + E+ Q+ +
Sbjct: 564  EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 623

Query: 4248 GVGIEQGKMDGDKNEQ--ERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRH 4305
                EQ +   ++ E+  E+   ++           L  + E   + + +     +Q + 
Sbjct: 624  EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683

Query: 4306 QKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKAL 4365
            +K  E  K       +     + +K ++    +E  E K+  E+++M  +++ ++ ++  
Sbjct: 684  EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER-EKKMREEEEMMREQEEKMQEQEEK 742

Query: 4366 SQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSK 4425
             Q       E  ++  E +E+  E     EQ  +  E E+ Q+ + +  ++EK    + K
Sbjct: 743  MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802



 Score = 50.4 bits (119), Expect = 6e-05
 Identities = 96/567 (16%), Positives = 245/567 (43%), Gaps = 45/567 (7%)

Query: 3888 QQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALE--KIMHSKRIALEVKQPSI 3945
            Q+EL +  E+ ++  +      EK +   +K   + E+  E  K M  +   +  ++  +
Sbjct: 340  QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 399

Query: 3946 FQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPN 4005
            +++ E  ++EK  +++E +++    +       +   +  T + EE M+ + R    +  
Sbjct: 400  WEQDE-RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK 458

Query: 4006 LQESSDTEKTAYEKCIS--DNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQ 4063
            ++E  +T +   EK     +N+    +K  +     EQ++K+ +   +++ +  I     
Sbjct: 459  MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW---- 514

Query: 4064 LDIKEQEKRI---EHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPEL 4120
                EQE++I   E + G+   +              + + +    E         + + 
Sbjct: 515  ----EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKK 570

Query: 4121 SHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHP-EDKGLKAK 4179
            + ++  +  ++ + +  +  +  + +K ++  +   + E K+  +++ M   E+K  + +
Sbjct: 571  TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630

Query: 4180 KALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGK--EDRRGAGQEKVDREDK---EQG 4234
            + + +      ++  KM ++ ++  ++ R  E++ K  E  +   QEK+  +++   EQ 
Sbjct: 631  EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690

Query: 4235 KMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQG 4294
            KM+ + +EQ+K      +Q KM  +++ +ER     +     +     +   E EE  Q 
Sbjct: 691  KMEKKTQEQEKKTW---DQEKMREEESMREREK--KMREEEEMMREQEEKMQEQEEKMQE 745

Query: 4295 IIRPGILQPRHQKSSETGKKA---NGVPS------EGDSASEVQKAKDYMQQKEEDEVKI 4345
              +   +  + +K  E  +K      +P       E +   E +K  +  ++  + E K+
Sbjct: 746  --QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKM 803

Query: 4346 SAEKDLMHPEDKDLKGK--KALSQNLPLNPKEPGKRDGE----GQEQGKEDG-EGEEQGN 4398
              +++ M  +++ ++G+  K   Q   +  +E      E    GQE+  E+  +G+E+  
Sbjct: 804  RGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKM 863

Query: 4399 RDGETEEQQQADGVGTEQEKRDGHKSK 4425
            R+ E + + Q + +  ++EK  G + K
Sbjct: 864  REQEEKMRGQEEKMREQEEKMRGQEEK 890



 Score = 48.1 bits (113), Expect = 3e-04
 Identities = 58/280 (20%), Positives = 124/280 (44%), Gaps = 33/280 (11%)

Query: 4153 QQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEA--QEQGKEDREG 4210
            +Q  + E K+  +++ M  +D+ L+ K+   ++     ++  KM +E   QEQ K+ R+ 
Sbjct: 383  KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442

Query: 4211 EEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLY 4270
            EE+ +E+ R   +EK  RE++E   M  + E+ QK +    EQ + +    +Q+R+    
Sbjct: 443  EEKMQEEERIREREKKMREEEET--MREQEEKMQKQEENMWEQEEKEW---QQQRL---- 493

Query: 4271 LPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEV-- 4328
                               E ++ +     +Q + +K  E  +K            ++  
Sbjct: 494  ------------------PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 535

Query: 4329 -QKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQG 4387
             +K ++   Q  E E K+  ++  M  +++ ++ KK   Q      +E   R+ E   + 
Sbjct: 536  QEKMREQEDQMWEQEEKMRDQEQKMWDQEERME-KKTQEQEKKTWDQEEKMREEERMRER 594

Query: 4388 KEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQE 4427
            ++    EE+  R+ E + Q+Q + +  ++EK    + K +
Sbjct: 595  EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 64.7 bits (156), Expect = 3e-09
 Identities = 123/570 (21%), Positives = 210/570 (36%), Gaps = 73/570 (12%)

Query: 3827 KEPQRSNKKLEKMTQEDESNLNVVQNKLC-ASILSPPHLEWNPRIKEVYMRGITRFCLSS 3885
            KE +    K E+  +E+E+     + K   A   + P  E    +KE           + 
Sbjct: 476  KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEE----------AK 525

Query: 3886 STQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSI 3945
            S  +  S   E+ + P +  + S EKAK   +++     +A        +   EVK P  
Sbjct: 526  SPAEAKSPEKEEAKSPAE--VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP-- 581

Query: 3946 FQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTI--EGEEAMRIKMRSSFSQ 4003
             ++ +   KE+     E K  E    P    +  P      +  E +    +K       
Sbjct: 582  -EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS 640

Query: 4004 PNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQ 4063
            P  +E+   EK    K      + S +KA   +  K + +  EK ++  K ++   +  +
Sbjct: 641  PTKEEAKSPEKA---KSPEKEEAKSPEKAKSPV--KAEAKSPEKAKSPVKAEAKSPEKAK 695

Query: 4064 LDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQ 4123
              +KE+ K  E  K  P      +     SP   +  T  +    V E  +   PE +  
Sbjct: 696  SPVKEEAKSPEKAKS-PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS--PEKA-- 750

Query: 4124 KSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALS 4183
            KS E  +  D  + +     K +        K  ++ K   K+++  PE    KAK  L 
Sbjct: 751  KSPEKAKTLDVKSPEAKTPAKEEARSP--ADKFPEKAKSPVKEEVKSPE----KAKSPLK 804

Query: 4184 QDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQ 4243
            +D     KE  K ++      +E++  E + KE  + A +EK     K + K D + EE 
Sbjct: 805  EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA 864

Query: 4244 QKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQP 4303
             K +            K E+++   +  P  S +     + + E  ED++ +  P    P
Sbjct: 865  PKKEA--------PKPKVEEKKEPAVEKPKESKV-----EAKKEEAEDKKKVPTPEKEAP 911

Query: 4304 RHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKIS-----AEKDLMHPEDKD 4358
               +  E  K                K K  + +KE D+ K       AEK    PE KD
Sbjct: 912  AKVEVKEDAKP---------------KEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956

Query: 4359 LKGKKALSQNLPLNPKEPGKRDGEGQEQGK 4388
             K +KA        P+E  K + + +E  K
Sbjct: 957  TKEEKA------KKPEEKPKTEAKAKEDDK 980



 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 140/765 (18%), Positives = 298/765 (38%), Gaps = 61/765 (7%)

Query: 3514 KLRLGKKIETQKANEKVQKEVCLPITLH--SLSASMPILQESKGQKDSVEQVIRKGVICH 3571
            ++RL +  E  K N    +     IT +   L A    L+  K  KDS+E+   +    H
Sbjct: 294  RVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRH 353

Query: 3572 KRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTD--KMVNVKHRMSEIDLVAAKICES 3629
            +   + +++++        D    + + EM   + +   ++NVK  + +I++ A +    
Sbjct: 354  QADIASYQEAI-----QQLDAELRNTKWEMAAQLREYQDLLNVKMAL-DIEIAAYR---K 404

Query: 3630 ILSLPHFKLNKETIDGVISSN---VKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKS 3686
            +L     ++    I   +      + S   HI     +++K ++    ++  +  +  ++
Sbjct: 405  LLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEET 464

Query: 3687 SLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAG--K 3744
             ++  ++ +E     +  ++EGK +EG  +   +     T  P    + S  +      K
Sbjct: 465  QVTEEVTEEEEK---EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK 521

Query: 3745 DKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKD 3804
            +++ +      P K +A S A  V S E     +     E+K  P+ K  ++E      +
Sbjct: 522  EEAKSPAEAKSPEKEEAKSPAE-VKSPEKAKSPAKE---EAKSPPEAKSPEKEEAKSPAE 577

Query: 3805 VMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHL 3864
            V      + +  KS  +         +S +K +   +E+  +    ++ +     SP  +
Sbjct: 578  VK-----SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632

Query: 3865 EWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVE 3924
            +   + K            + S ++E + + EK + P+     S EKAK   + +    E
Sbjct: 633  KSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE 692

Query: 3925 KALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKV 3984
            KA   +    +   + K P + +E +   K K    +E K  E    P    +  P    
Sbjct: 693  KAKSPVKEEAKSPEKAKSP-VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK 751

Query: 3985 GTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVK--KALESILQKEQR 4042
                 E+A  + ++S  ++   +E + +    + +     +   VK  +  +S L+++ +
Sbjct: 752  SP---EKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808

Query: 4043 QKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTR 4102
               ++I   +++KS +        KE+EK  E    EP        A     +  + D++
Sbjct: 809  APEKEIPKKEEVKSPV--------KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK 860

Query: 4103 REKAEYVT----EITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDD 4158
            +E+A        ++     P +   K S+   K +    K  +    ++A   ++ KED 
Sbjct: 861  KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDA 920

Query: 4159 EVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKE--PGKMD--QEAQEQGKEDREGEEQG 4214
            + K   +     P+D      KA     P   KE  P K D  +E  ++ +E  + E + 
Sbjct: 921  KPKEKTEVAKKEPDD-----AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKA 975

Query: 4215 KEDRRGAGQE----KVDREDKEQGKMDHEVEEQQKADGVGIEQGK 4255
            KED +   +E    K ++ +K       + +  +KA      +GK
Sbjct: 976  KEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020



 Score = 53.5 bits (127), Expect = 7e-06
 Identities = 93/515 (18%), Positives = 189/515 (36%), Gaps = 53/515 (10%)

Query: 3914 HMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPF 3973
            H+  K ++++ K +EK      I  E  + +   E     +EK  K +E KE E      
Sbjct: 435  HIKVKSEEKI-KVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE------ 487

Query: 3974 ASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKAL 4033
                           GEE            P  +E++  EK A      +  S +  K+ 
Sbjct: 488  --------------GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533

Query: 4034 ESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPS 4093
            E    KE+ +   ++++ +K KS   +  +   + +    E  K  P+ + +   A  P+
Sbjct: 534  E----KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS-PAEVKSPEKAKSPA 588

Query: 4094 PSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKV-QKAKDYM 4152
                +     +  E          P     KS    +      +K    +K  +KAK   
Sbjct: 589  KEEAKSPAEAKSPEKAKS------PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642

Query: 4153 QQ--KEDDEVKISAKKDIMHPEDKGLKAKKALSQDL--PLNTKEPGKMDQEAQEQGKEDR 4208
            ++  K  ++ K   K++   PE    KAK  +  +   P   K P K + ++ E+ K   
Sbjct: 643  KEEAKSPEKAKSPEKEEAKSPE----KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698

Query: 4209 EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLF 4268
            + E +  E  +   +E+    +K +  +  E +  +KA     E+ K        E+   
Sbjct: 699  KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758

Query: 4269 LYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEV 4328
            L + S  + T    + R   ++  +    P   + +  + +++  K +    E +   + 
Sbjct: 759  LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818

Query: 4329 QKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGK 4388
            +      ++++  EVK+                KKA  +  P  PK   K+D + +E  K
Sbjct: 819  EVKSPVKEEEKPQEVKVKEPP------------KKAEEEKAPATPKTEEKKDSKKEEAPK 866

Query: 4389 EDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHK 4423
            ++    +   +     E+ +   V  ++E+ +  K
Sbjct: 867  KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901



 Score = 43.9 bits (102), Expect = 0.006
 Identities = 104/567 (18%), Positives = 209/567 (36%), Gaps = 43/567 (7%)

Query: 3886 STQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSI 3945
            S Q+E+++   + +    + L +++  K   ++ +  +E   +  + S + A++     +
Sbjct: 313  SAQEEITEYRRQLQARTTE-LEALKSTKDSLERQRSELEDRHQADIASYQEAIQ----QL 367

Query: 3946 FQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPN 4005
              EL     E   +++E +++ +  K    I    Y K+  +EGEE         FS P 
Sbjct: 368  DAELRNTKWEMAAQLREYQDL-LNVKMALDIEIAAYRKL--LEGEECRIGFGPIPFSLPE 424

Query: 4006 LQESSDTEKTAYEKCISDNISNSVKKALESIL---QKEQRQKMEKIRALKKMKSSISQGI 4062
                  +  T  +    + I    K   E+++   Q E+ Q  E++   ++ ++   +G 
Sbjct: 425  GLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGK 484

Query: 4063 QLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSH 4122
            + +  E+E+     +G      +       SP        +E+A+   E       E   
Sbjct: 485  EEEGGEEEEA----EGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540

Query: 4123 QKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKAL 4182
                ++ EKA   A +   +    K+ +  + K   EVK   K      E+    A+   
Sbjct: 541  PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600

Query: 4183 SQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEE 4242
             +      KE  K   EA+   KE+ +   + K   +     K + +  E+ K     +E
Sbjct: 601  PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE--KE 658

Query: 4243 QQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQ 4302
            + K+        K +    E+ +        +       +    +  E  +  ++     
Sbjct: 659  EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718

Query: 4303 PRHQKS-----SETGKKANGVPSEGDSASEVQKAKDYMQQKEED----EVKISAEKDLMH 4353
            P   KS     ++T +KA     E   A   +KAK   + K  D    E K  A+++   
Sbjct: 719  PEKAKSPVKEEAKTPEKAKSPVKE--EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS 776

Query: 4354 PEDK-DLKGKKALSQNL--PLNPKEPGKRDGEGQEQ------------GKEDGEGEEQGN 4398
            P DK   K K  + + +  P   K P K D +  E+             +E+   E +  
Sbjct: 777  PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836

Query: 4399 RDGETEEQQQADGVGTEQEKRDGHKSK 4425
               +  E+++A      +EK+D  K +
Sbjct: 837  EPPKKAEEEKAPATPKTEEKKDSKKEE 863



 Score = 38.5 bits (88), Expect = 0.24
 Identities = 48/223 (21%), Positives = 96/223 (43%), Gaps = 12/223 (5%)

Query: 6207 PQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQ 6266
            P PF++  + + K+P+V +   ++SE   K ++   KE ++ E        +    + E+
Sbjct: 417  PIPFSLP-EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEE--TQVTEEVTEE 473

Query: 6267 EEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKS- 6325
            EEK  K      E     E+ +  ++  +S P  +  + + + +         P + KS 
Sbjct: 474  EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533

Query: 6326 --SEVKIVADSTNAEHL-LPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKP--DDLK 6380
               E K  A+  + E    P  E  K+  E++     + K  ++     +A  P  ++ K
Sbjct: 534  EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593

Query: 6381 SPPFPEGPDTISTAIYPKTQHKSLLEQFTP-KEKNKLTSHLES 6422
            SP   + P+   + +  K + KS  E  +P KE+ K  + ++S
Sbjct: 594  SPAEAKSPEKAKSPV--KEEAKSPAEAKSPVKEEAKSPAEVKS 634


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 203/1000 (20%), Positives = 407/1000 (40%), Gaps = 161/1000 (16%)

Query: 3827 KEPQRSNKKLEKMTQE----DESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFC 3882
            KE   +  K++ +T+E    DE+   + + K                ++E + + +    
Sbjct: 967  KEKHATENKVKNLTEELSGLDETIAKLTREKKA--------------LQEAHQQALDDLQ 1012

Query: 3883 LSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALE---KIMHSKRIALE 3939
                    L+ T  K EQ ++D  SS+E+ K + + D +R ++ LE   K+     + LE
Sbjct: 1013 AEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKL-RVDLERNKRKLEGDLKLAQESILDLE 1071

Query: 3940 VKQPSIFQELELNIKEKG-------GKIQEDKEVEI-WSKPFASISFLPYSKVGTIEGEE 3991
              +    Q+L+  +K+K         K+++++ + + + K    +          IE E 
Sbjct: 1072 NDK----QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127

Query: 3992 AMRI---KMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKA----LESILQKEQRQK 4044
            A R    K RS +++  L+E S+  + A     +    N  ++A    L   L++   Q 
Sbjct: 1128 ATRAKTEKQRSDYAR-ELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQH 1186

Query: 4045 MEKIRAL-KKMKSSISQ-GIQLD-IKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQ--- 4098
               + AL KK   S+++ G Q+D ++  ++++E  K E  + + +  +S+ S S  +   
Sbjct: 1187 EAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 1246

Query: 4099 ------LDTRREKAEYVTEITRYYLPELSHQKS---SEAGEKADGVASKGDITIKVQKAK 4149
                  L+ +  +A    E  +  L EL+ QKS   +EAGE +  +  K  I  ++ ++K
Sbjct: 1247 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 1306

Query: 4150 DYMQQKEDD-----EVKISAKKDIMH----------------PEDKGLKAK------KAL 4182
                Q+ ++     E +  AK  + H                 E++  KA+      KA 
Sbjct: 1307 QAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKAN 1366

Query: 4183 SQDLPLNTKEPGKMDQ--EAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEV 4240
            S+     TK      Q  E  E+ K+      Q  E++  A   K    +K + ++  EV
Sbjct: 1367 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEV 1426

Query: 4241 E------EQQKADGVGIEQGKMDGDK---------NEQERVLFLYLPSNSSLTHYILDTR 4285
            E      E+  +    +++ + + DK          E +  L   L  + SL+  +   +
Sbjct: 1427 EDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLK 1486

Query: 4286 IEGEE--DQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEV 4343
               EE  DQ   ++    +       E       +   G +  E++K++  ++ ++ D +
Sbjct: 1487 NAYEEALDQLETVK----RENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKAD-I 1541

Query: 4344 KIS---AEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEE--QGN 4398
            +++   AE  L H E K L+ +  L+Q      ++  ++D E ++  +      E  Q  
Sbjct: 1542 QLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSA 1601

Query: 4399 RDGETEEQQQA-------DGVGTEQEKRDGHKSKQETVLFLHLPS---ESSLTCYELNTR 4448
             D E   + +A       +G   E E +  H ++Q      HL S   +   T   L+  
Sbjct: 1602 LDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDA 1661

Query: 4449 KEGEEDLQ----------GIIKSATLQLRQ--QKSFDAGKIAHTKSFGVDSSNDVKTVQE 4496
              G+EDL+           ++++   +LR   +++  A K+A  +   +DS+  V+ +  
Sbjct: 1662 LRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL--LDSNERVQLLHT 1719

Query: 4497 YKPQKEVDRGKTVSVDYIMQPEGTIFEA--EQLSLPHTLNIPGSSGSKTREVLTNIKEKL 4554
                  +   K +  D +MQ +  + +A  +  +         +  +   E L   ++  
Sbjct: 1720 QNTSL-IHTKKKLETD-LMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTS 1777

Query: 4555 RHVQERKSELDVFLTIPSLSHCKLDKR-----TAGKKEEQGVTRSFLPPSWHME---SSD 4606
             H++  K  L+   T+  L H +LD+        GKK+ Q +        + +E     +
Sbjct: 1778 AHLERMKKNLE--QTVKDLQH-RLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKN 1834

Query: 4607 TGKLKYTLSY---LNDITGDSNR-TKYMAQIQK--DKANISEKSVMHPEYIAVKAEKSPL 4660
            T  +K    Y   + ++T  S    K + ++Q   DK  +  KS       A +A++   
Sbjct: 1835 TESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQ---AEEADEQAN 1891

Query: 4661 SHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTS 4700
            +H+ K ++ Q  + +  E+A   E ++  L +KT  F +S
Sbjct: 1892 AHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSS 1931



 Score = 47.4 bits (111), Expect = 5e-04
 Identities = 136/664 (20%), Positives = 255/664 (38%), Gaps = 122/664 (18%)

Query: 4147 KAKDYMQQKEDDEVKISAKKDIMHPEDKGLKA---KKALSQDLPLNTKEPGKMDQEAQEQ 4203
            K K  ++  E ++   + K++    +D+  K+   +K L + L    +E   +  + Q +
Sbjct: 836  KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895

Query: 4204 GKEDREGEEQGKE---------------DRRGAGQEKVDRE-DKEQGKMDHEVEEQQK-A 4246
             +   + EE+  +                 R   +E+++ E   ++ K++ E  E +K  
Sbjct: 896  SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955

Query: 4247 DGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQ 4306
            D + +   K++ +K+  E  +       S L   I     E +           LQ  HQ
Sbjct: 956  DDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKA----------LQEAHQ 1005

Query: 4307 KSSETGKKANGVPSEGDSASEVQKAKDYMQQKEED-EVKISAEKDL---MHPEDKDLKGK 4362
            ++ +       + +E D  + + K K  ++Q+ ED E  +  EK L   +    + L+G 
Sbjct: 1006 QALDD------LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGD 1059

Query: 4363 KALSQNLPL---NPKEP-----GKRDGEG-QEQGKEDGEG----------EEQGNRDGET 4403
              L+Q   L   N K+       K+D E  Q Q K + E           +E   R  E 
Sbjct: 1060 LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL 1119

Query: 4404 EEQ---QQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGE-EDLQGII 4459
            EE+   ++A    TE+++ D  +  +E    L      + T  ELN ++E E   L+  +
Sbjct: 1120 EEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDL 1179

Query: 4460 KSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEG 4519
            + ATLQ   +    A +  H  S   +    +  +Q  K + E ++ +            
Sbjct: 1180 EEATLQ--HEAMVAALRKKHADSV-AELGEQIDNLQRVKQKLEKEKSEFK---------- 1226

Query: 4520 TIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLD 4579
               E + LS         SS     +   N+++  R ++++ SE                
Sbjct: 1227 --LEIDDLS---------SSMESVSKSKANLEKICRTLEDQLSE---------------- 1259

Query: 4580 KRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTK--YMAQIQKDK 4637
                GK EE   + S L        ++ G+L   L     I    +R+K  +  Q ++ K
Sbjct: 1260 --ARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 1317

Query: 4638 ANISEKSVMHPEYIAVKAEKSPLSHILKTKELQVN-ISQQGEKAQEGEVEIVVLLSKTCP 4696
              + E++            K+ L+H L++     + + +Q E+ QEG+ E+   LSK   
Sbjct: 1318 RQLEEEN----------KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1367

Query: 4697 FVTS-SAFLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLP 4755
             V       E D+I+  E      +     L+  E    +  A      SL K +++L  
Sbjct: 1368 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSE---EQVEAVNAKCASLEKTKQRLQG 1424

Query: 4756 QKED 4759
            + ED
Sbjct: 1425 EVED 1428



 Score = 35.4 bits (80), Expect = 2.0
 Identities = 89/465 (19%), Positives = 181/465 (38%), Gaps = 67/465 (14%)

Query: 494  LKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHE-----RKDISDIALHLISVSK 548
            +KAK    +++ ++T     ++  E+  +   +K++L +     +KDI D+ L L  V K
Sbjct: 910  IKAKFQLEAKIKEVT--ERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 967

Query: 549  LILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKE 608
                +      K L + + GL +    L ++ K+           L+E     +   + E
Sbjct: 968  E--KHATENKVKNLTEELSGLDETIAKLTREKKA-----------LQEAHQQALDDLQAE 1014

Query: 609  YDKENK--RLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIG 666
             DK N   + K+   + +  LE S              +E   K +  L+ +  + +G  
Sbjct: 1015 EDKVNSLNKTKSKLEQQVEDLESS--------------LEQEKKLRVDLERNKRKLEGD- 1059

Query: 667  ITEFHVLNSKKPFDLHIPKHKTSLEEAISKP---MQKLVSSPEMESNNRMKIQEDLQSSE 723
                  L   +   L +   K  L+E + K      +L S  E E    ++ Q+ ++  +
Sbjct: 1060 ------LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQ 1113

Query: 724  NSHLQLSNGEELPTSTPKTQRCFPRENTQKQK-----DFLELVLELSNVGLLISPGSKMH 778
                +L    E   +T        R  T+KQ+     +  EL   L   G + S   +++
Sbjct: 1114 ARIEELEEEIEAERAT--------RAKTEKQRSDYARELEELSERLEEAGGVTSTQIELN 1165

Query: 779  KSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETS 838
            K   E E +K++ + E   L+    +     + +D           G  I N+ + K+  
Sbjct: 1166 KK-REAEFLKLRRDLEEATLQHEAMVAALRKKHADS------VAELGEQIDNLQRVKQKL 1218

Query: 839  DAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKS 898
            +   S     I  L  +   S+SK+KA+  +I R       + +  +E+  ++   +   
Sbjct: 1219 EKEKSEFKLEIDDL-SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 1277

Query: 899  CTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQ 943
             +  + +  +   Q +E  S ++Q  R      Q+ + +K Q+E+
Sbjct: 1278 KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEE 1322


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
            sapiens]
          Length = 1220

 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 125/607 (20%), Positives = 241/607 (39%), Gaps = 97/607 (15%)

Query: 3888 QQELSDTMEKCEQPIDDSLSSIEKA----KHMPQKDKDRVEKALEKIMHSKRIALEVKQP 3943
            Q+  S+   K +  +D   + IE A    +  PQK K + +K  +K         +  + 
Sbjct: 5    QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKK--------QDFDED 56

Query: 3944 SIFQELE-LNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFS 4002
             I +ELE L+++ +G  I+ D+E  +  KP  +      SK    +G++  +     + S
Sbjct: 57   DILKELEELSLEAQG--IKADRET-VAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDS 113

Query: 4003 QPNLQESSDTEKTA------YEKCISDNISNSVKKALESILQK---------EQRQKMEK 4047
            +    + S ++KTA      Y     D+  N + K  +   QK         E     +K
Sbjct: 114  EELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173

Query: 4048 IRALKKMKSSISQGIQLD----IKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRR 4103
            I+   ++ SS   G + D     ++ +K+ +  K  P++   N        +  ++ T  
Sbjct: 174  IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNE----DDDASFKIKTVA 229

Query: 4104 EKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDI-TIKVQKAKDYMQQKEDDEVKI 4162
            +K     E  R        +K  E   K   +  K ++ T K  ++K    Q++ +E  +
Sbjct: 230  QKKAEKKERER--------KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV 281

Query: 4163 SAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAG 4222
             +K  +    D G+        + P   ++  + D++ +++ K+  E EE+ KE ++G  
Sbjct: 282  KSKVTV----DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS 337

Query: 4223 -----------------QEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQER 4265
                             +E+  RE++E+ K   E+E ++K +   +EQ K +  K +++ 
Sbjct: 338  KATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE-RLEQEKRERKKQKEKE 396

Query: 4266 VLFLYLPSNSSLTHYILDTRIEGEE-----DQQGIIRPGILQPRHQKSSETGKKANGVPS 4320
                       LT    + R   E        QG+  P       ++     KK   +P 
Sbjct: 397  RKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQ 456

Query: 4321 EGDS-----ASEVQKAKDYMQQ-------------KEEDEVKISAEKDLMHPEDKDLKGK 4362
            + +S     + E+  A + M+Q              EE+E    A  D       D + +
Sbjct: 457  QLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETE 516

Query: 4363 KALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGH 4422
            K     + +  KE  + + E +E+ +ED E EE+   +GE+E  +  +    E EK    
Sbjct: 517  KVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDE----EDEKVSDE 572

Query: 4423 KSKQETV 4429
            K   +T+
Sbjct: 573  KDSGKTL 579



 Score = 53.9 bits (128), Expect = 6e-06
 Identities = 81/396 (20%), Positives = 172/396 (43%), Gaps = 56/396 (14%)

Query: 3911 KAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVE--- 3967
            K K + QK  ++ E+  +K    K    ++K+    +ELE   K++  + +  ++ E   
Sbjct: 224  KIKTVAQKKAEKKERERKKRDEEKAKLRKLKEK---EELETGKKDQSKQKESQRKFEEET 280

Query: 3968 IWSKPFASISFLPYSKVGT-----IEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCIS 4022
            + SK       +P S+         E +     K +    +   +E  + EK   +K  S
Sbjct: 281  VKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEK---KKGPS 337

Query: 4023 DNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRI--------- 4073
                 ++++AL  + ++E+RQK E+   +K+++   ++  + +  EQEKR          
Sbjct: 338  KATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKER 397

Query: 4074 -EHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLP------ELSHQKSS 4126
             E +K E  +L  +      + +  +   +  +A+ V   ++  LP      E   +K  
Sbjct: 398  KERLKKEGKLLTKS---QREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKI 454

Query: 4127 EAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQD- 4185
                ++  V+   ++   V+  +  + +KE+    +  +++    ED GL   +A++ D 
Sbjct: 455  PQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEE-EDTEDAGLDDWEAMASDE 513

Query: 4186 ---------LPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDRED------ 4230
                     + +  KE  + ++E +E+ +ED E EE+ +E+    G E  D ED      
Sbjct: 514  ETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEG-DEEDEKVSDE 572

Query: 4231 KEQGK-MDHEVEEQQKADGVGIEQGKMDGDKNEQER 4265
            K+ GK +D +  ++  +D     +   D D+ ++ER
Sbjct: 573  KDSGKTLDKKPSKEMSSD----SEYDSDDDRTKEER 604



 Score = 37.7 bits (86), Expect = 0.41
 Identities = 54/253 (21%), Positives = 103/253 (40%), Gaps = 26/253 (10%)

Query: 4194 GKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQ-KADGV--G 4250
            GK  +   E   +D    +    +  GAG  K     K +GK   E ++Q    D +   
Sbjct: 2    GKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61

Query: 4251 IEQGKMDGDKNEQERVLFLYLPSNSSLTHYI-LDTRIEGEEDQQGIIRPG---ILQPRHQ 4306
            +E+  ++    + +R      P+ ++   +   D + +G++ ++          L+ +  
Sbjct: 62   LEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121

Query: 4307 KSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALS 4366
            KS +T K    + S  D   +  K    + +K + + + S +K     ED+D   KK   
Sbjct: 122  KSKKTAKPKVEMYSGSDDDDDFNK----LPKKAKGKAQKSNKKWDGSEEDED-NSKKIKE 176

Query: 4367 QNLPLNPKEPG--------KRDGEGQEQGKEDGEGEEQGNRDGE------TEEQQQADGV 4412
            ++   +  E G         R G+ + Q  + G   E GN D +      T  Q++A+  
Sbjct: 177  RSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKK 236

Query: 4413 GTEQEKRDGHKSK 4425
              E++KRD  K+K
Sbjct: 237  ERERKKRDEEKAK 249



 Score = 37.7 bits (86), Expect = 0.41
 Identities = 100/525 (19%), Positives = 187/525 (35%), Gaps = 70/525 (13%)

Query: 439 QLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNVPSLKAKK 498
           + + +KA  +   V    N +  ++S       KGQK ++++ D      L     K+KK
Sbjct: 68  EAQGIKADRETVAVKPTENNEEEFTSKDKKK--KGQKGKKQSFDDNDSEELEDKDSKSKK 125

Query: 499 TPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLILPYVKNYS 558
           T   +V   +      + N+L  K   + ++ +++ D S+                ++  
Sbjct: 126 TAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSE----------------EDED 169

Query: 559 RKQLVKVMPGLIKCGH-------FLQKQNKSPDTEKINYAGPLEETGISD---------- 601
             + +K    +   G        FLQ +      +K N  GP  E+G  D          
Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQK-NKPGPNIESGNEDDDASFKIKTV 228

Query: 602 ----ITKKEKEY---DKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKES 654
                 KKE+E    D+E  +L+ +  K   +LE      + Q ++     E   KSK +
Sbjct: 229 AQKKAEKKERERKKRDEEKAKLRKLKEK--EELETGKKDQSKQKESQRKFEEETVKSKVT 286

Query: 655 LKDSIT-----QAKGIGITEFHVLNSKKPFDLHIPK-HKTSLEEAISKPMQKLVSSPEME 708
           +   +      +A+     E      KK  D    K  K   E+   K   K       E
Sbjct: 287 VDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQE 346

Query: 709 SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 768
           +  ++K +E+ Q  E    ++   EEL     + +R    +  +K++   E    L   G
Sbjct: 347 ALAKLKEEEERQKREEEE-RIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEG 405

Query: 769 LLISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRE-SEELECNTGSN 827
            L++   +  ++  E     +Q     V  K+S P    + ED   ++  ++LE    S 
Sbjct: 406 KLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSE 465

Query: 828 ITNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQE------ 881
              +    E  +        T   +   E      A  D    +       K E      
Sbjct: 466 SMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHI 525

Query: 882 ---KLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQG 923
              + P+E+E +  E        ++  +   +E+E+E  SE ++G
Sbjct: 526 EVKENPEEEEEEEEE--------EEEDEESEEEEEEEGESEGSEG 562


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 62.0 bits (149), Expect = 2e-08
 Identities = 127/623 (20%), Positives = 247/623 (39%), Gaps = 76/623 (12%)

Query: 4103 REKAEYVTEITRYYLPELSHQKSSEAGEKADGV--ASKGDITI----KVQKAKDYMQQKE 4156
            R+  E  T+    +   LS   SSE  E  DG     KG+I      K +  KD  +++E
Sbjct: 93   RDAMEETTDWIYGFFSLLSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQE 152

Query: 4157 DDEVKISAKKDIMHPE-DKGL-------KAKKALSQDLPLNTKEPGKMDQEAQEQ--GKE 4206
              E KI  K  + H E +KG        K +K  +    +  KE  +    A+EQ   K 
Sbjct: 153  KPERKIQTK--VTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKT 210

Query: 4207 DREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERV 4266
              + EE+ K++ +G  QEKV    K+      EV++         ++ K    K+EQ+  
Sbjct: 211  AEKSEEKTKKEVKGGKQEKV----KQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQK-- 264

Query: 4267 LFLYLPSNSSLTHYILDTRIEGE--EDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDS 4324
                     +   Y++D  + G+    Q   I P +  P  Q S  T         EG+ 
Sbjct: 265  ------DQYAFCRYMIDIFVHGDLKPGQSPAIPPPL--PTEQASRPTPASPALEEKEGEK 316

Query: 4325 ASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQ--NLPLNPKEPGKRDGE 4382
                +K     ++KE++++K  +EK+     +K   GK + ++   + +  +   K+D E
Sbjct: 317  KKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKD-E 375

Query: 4383 GQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTC 4442
             +E  K+  +  E     G+ +E+++      +  K++      + V      ++  +  
Sbjct: 376  KKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGA 435

Query: 4443 YELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKE 4502
              +     G+++ +   K+   ++R++KS     I   K         +K  +E  P   
Sbjct: 436  VSIKKAVPGKKE-EKTTKTVEQEIRKEKSGKTSSILKDK-------EPIKGKEEKVPASL 487

Query: 4503 VDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKS 4562
             ++      D  M   G   + +          P   G K  +    IK++ +     K 
Sbjct: 488  KEKEPETKKDEKMSKAGKEVKPKP---------PQLQGKKEEKPEPQIKKEAKPAISEKV 538

Query: 4563 EL---DVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLP----PSWHME----SSDTGKLK 4611
            ++   D+     ++SH K +++   + +   + ++  P     + H E    S  T K K
Sbjct: 539  QIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPK 598

Query: 4612 YTLSYLNDIT-GDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQ 4670
             T    +++T     +T+   +  K+KA++     +  E ++ + E   L ++ K  E  
Sbjct: 599  PTPKGTSEVTESGKKKTEISEKESKEKADMKH---LREEKVSTRKESLQLHNVTKA-EKP 654

Query: 4671 VNISQQGE------KAQEGEVEI 4687
              +S+  E      KA+EG  ++
Sbjct: 655  ARVSKDVEDVPASKKAKEGTEDV 677



 Score = 50.4 bits (119), Expect = 6e-05
 Identities = 112/540 (20%), Positives = 208/540 (38%), Gaps = 89/540 (16%)

Query: 3893 DTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKAL-----EKIMHSKRIALEV-KQPSIF 3946
            + +EK E+P   +L+  +K     +K +++ +K +     EK+  +     EV K PS  
Sbjct: 188  EKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKP 247

Query: 3947 QELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVG---TIEGEEAMRIKMRSSFSQ 4003
            +E E   K    K  E K+   + +    I      K G    I          R + + 
Sbjct: 248  KEKEDKEKAAVSK-HEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPAS 306

Query: 4004 PNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQ------KMEKIRALKKMKSS 4057
            P L+E    +K A +K  S+    + KK  E I +K +++      K E  +A +  + +
Sbjct: 307  PALEEKEGEKKKAEKKVTSE----TKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGT 362

Query: 4058 ISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYL 4117
            +    Q   K+ EK+ +  K       T   A +  P       ++EK E          
Sbjct: 363  VKIAAQAAAKKDEKKEDSKK-------TKKPAEVEQPK----GKKQEKKE---------- 401

Query: 4118 PELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLK 4177
                H + +++ +K   V S   +  K ++AK+ +         +S KK +  P  K  K
Sbjct: 402  ---KHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGA-------VSIKKAV--PGKKEEK 449

Query: 4178 AKKALSQDLP----------LNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVD 4227
              K + Q++           L  KEP K  +E      +++E E +  E    AG+E   
Sbjct: 450  TTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKP 509

Query: 4228 REDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIE 4287
            +  + QGK + + E Q K +       K+   K +        +    +++H   + ++ 
Sbjct: 510  KPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQD-------IVKPEKTVSHGKPEEKV- 561

Query: 4288 GEEDQQGIIRPGILQPRHQKSSETGK---------KANGVPSEGDSASEVQKAKDYMQQK 4338
              +  + +      +P+  K +E  +         K    P      +E  K K  + +K
Sbjct: 562  -LKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEK 620

Query: 4339 EEDEVKISAEKDLMH-PEDKDLKGKKALSQNLPLNPKEPGK--RDGEGQEQGKEDGEGEE 4395
            E  E     + D+ H  E+K    K++L  +     ++P +  +D E     K+  EG E
Sbjct: 621  ESKE-----KADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTE 675



 Score = 39.3 bits (90), Expect = 0.14
 Identities = 129/622 (20%), Positives = 226/622 (36%), Gaps = 134/622 (21%)

Query: 4226 VDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTR 4285
            +  ED+E    D + ++ +  D   + + ++  DK E++       P     T      +
Sbjct: 114  ISSEDEEDDDGDEDTDKGE-IDEPPLRKKEIHKDKTEKQEK-----PERKIQTKVTHKEK 167

Query: 4286 IEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKI 4345
             +G+E  +   +P   +  H++  E  +K    P     A E +KAK   + +E+ + ++
Sbjct: 168  EKGKEKVREKEKPE-KKATHKEKIEKKEK----PETKTLAKEQKKAKTAEKSEEKTKKEV 222

Query: 4346 SAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNR------ 4399
               K     + K    K    Q  P  PKE  K D E     K + + +    R      
Sbjct: 223  KGGKQ---EKVKQTAAKVKEVQKTPSKPKE--KEDKEKAAVSKHEQKDQYAFCRYMIDIF 277

Query: 4400 ------DGE---------TEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYE 4444
                   G+         TE+  +        E+++G K K E      + SE       
Sbjct: 278  VHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEK----KVTSE------- 326

Query: 4445 LNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVD 4504
              T+K+ +ED++   +  T    ++K  + GK + TK   V  +         K +K+ D
Sbjct: 327  --TKKKEKEDIKKKSEKETAIDVEKK--EPGKASETKQGTVKIAAQAAAK---KDEKKED 379

Query: 4505 RGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSEL 4564
              KT     + QP+G   E ++  +      P  S  K   V ++ + K +   ER  E 
Sbjct: 380  SKKTKKPAEVEQPKGKKQEKKEKHVE-----PAKSPKKEHSVPSDKQVKAK--TERAKE- 431

Query: 4565 DVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDS 4624
                    +    + K   GKKEE+                                   
Sbjct: 432  -------EIGAVSIKKAVPGKKEEK----------------------------------- 449

Query: 4625 NRTKYMAQ-IQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEG 4683
              TK + Q I+K+K+  +   +   E I  K EK P S  LK KE +   +++ EK  + 
Sbjct: 450  -TTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPAS--LKEKEPE---TKKDEKMSKA 503

Query: 4684 EVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQESL-------PSRQ 4736
              E+     K  P        +L   KEE+ EP+I +   P +  +  +       P + 
Sbjct: 504  GKEV-----KPKP-------PQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKT 551

Query: 4737 TAPTKPTESLVKKEKQLLPQKEDRVQTV--SMHGLMHPNGAVFKAKTSAPPQVFSITEHS 4794
             +  KP E ++K+ K +  +K  + +    + H    P           P     +TE S
Sbjct: 552  VSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTE-S 610

Query: 4795 PLSKRKEPQWGMKERAGQKQDR 4816
               K +  +   KE+A  K  R
Sbjct: 611  GKKKTEISEKESKEKADMKHLR 632


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 828

 Score = 60.5 bits (145), Expect = 6e-08
 Identities = 118/648 (18%), Positives = 269/648 (41%), Gaps = 106/648 (16%)

Query: 3792 KKEDR--ENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKM-----TQEDE 3844
            KK DR  E +   +D + L+         L+R+ +  +E ++ N +L++      +++ E
Sbjct: 155  KKADRYIEELTKERDALSLE---------LYRNTITNEELKKKNAELQEKLRLAESEKSE 205

Query: 3845 SNLNV--VQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPI 3902
              LNV  ++ KL  +    P ++ N   +E++ +           ++EL +  +K  +  
Sbjct: 206  IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ-----------EEELREQEKKIRKQE 254

Query: 3903 DDSLSSIEKAKHMPQKDKDRVEKAL--EKIMHSKRIALEVKQPSIFQELELNIKEKGGKI 3960
            +      E+ +    K +++ EK    EK +  +   L  ++  + ++ +L  +E+  + 
Sbjct: 255  EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314

Query: 3961 QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKC 4020
            QE+K  E   K       +   +    E E+ MR +          Q+  D E+  +E+ 
Sbjct: 315  QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE---------QKMRDQEERMWEQ- 364

Query: 4021 ISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEP 4080
              + +    ++  E     EQ +KM++   +++ +  + +  +  ++EQE++++      
Sbjct: 365  -DERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET-MREQEEKMQ------ 416

Query: 4081 SVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGD 4140
                                 ++E+  +  E   +    L  QK     ++         
Sbjct: 417  ---------------------KQEENMWEQEEKEWQQQRLPEQKEKLWEQE--------- 446

Query: 4141 ITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEA 4200
               K+Q+ ++ + ++E+   KI  ++++   E K  + +K   Q+  +  +E    DQE 
Sbjct: 447  ---KMQEQEEKIWEQEE---KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500

Query: 4201 QEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDK 4260
            +   +E+R  E+    D R   +E+  RE K+  + + ++ E++K      EQ K   D+
Sbjct: 501  KMWDQEERMWEQ----DERLREKEERMREQKKMWQQEEKMREEKKTQ----EQEKKTWDQ 552

Query: 4261 NEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPS 4320
             E+ R           +           EE++    +   +Q + +K  E  +K      
Sbjct: 553  EEKMREEERMREREKKMR----------EEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602

Query: 4321 EGDSASEV--QKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGK 4378
            +     E   ++ +   +Q+EED+++   E      E    + +K   Q   +  +E   
Sbjct: 603  KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662

Query: 4379 RDGEGQEQGKEDGEGEEQGNRDGETEE-QQQADGVGTEQEKRDGHKSK 4425
            R+ E + QG+E+   E++    G+ E+ ++Q + +  ++EK  G + K
Sbjct: 663  REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710



 Score = 49.7 bits (117), Expect = 1e-04
 Identities = 80/436 (18%), Positives = 179/436 (41%), Gaps = 60/436 (13%)

Query: 4037 LQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSH 4096
            L+K+  +  EK+R  +  KS I    QL++KE ++++E  K     + TN          
Sbjct: 185  LKKKNAELQEKLRLAESEKSEI----QLNVKELKRKLERAKFLLPQVQTNT--------- 231

Query: 4097 LQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQ---------- 4146
            LQ +  R++ E   +  +    E    +  E   + +G   + +  ++ Q          
Sbjct: 232  LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKE 291

Query: 4147 ------------KAKDYMQQKEDDEVKISAKKDIMHPEDKGL---------KAKKALSQD 4185
                        K ++  +Q ++ E K+  +++ M  +++ +         + K+   Q+
Sbjct: 292  LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351

Query: 4186 LPLNTKEPGKMDQEAQEQGKEDR--------EGEEQGKEDRRGAGQEKVDREDKEQGKMD 4237
              +  +E    +Q+ + + KE+R        E EE+ +E+ R   +EK  RE++E   M 
Sbjct: 352  QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET--MR 409

Query: 4238 HEVEEQQKADGVGIEQGKMDGDKN----EQERVLFLYLPSNSSLTHYILDTRIEGEEDQQ 4293
             + E+ QK +    EQ + +  +     ++E++             +  + +I  +E+  
Sbjct: 410  EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469

Query: 4294 GIIRPGILQP--RHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDL 4351
            G  +    Q   R Q+     ++      E     + ++  +  ++  E E ++  +K +
Sbjct: 470  GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529

Query: 4352 MHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADG 4411
               E+K  + KK   Q      +E   R+ E   + ++    EE+  R+ E + Q+Q + 
Sbjct: 530  WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589

Query: 4412 VGTEQEKRDGHKSKQE 4427
            +  ++EK    + K +
Sbjct: 590  MREQEEKMWEQEEKMQ 605


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 60.5 bits (145), Expect = 6e-08
 Identities = 357/1915 (18%), Positives = 711/1915 (37%), Gaps = 350/1915 (18%)

Query: 3599 LEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNK-ETIDGVISSNVKSTKQH 3657
            ++ Q  + + + ++K     I+ + +KI E +    H + N  ET D      V   K+ 
Sbjct: 960  IDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQ 1019

Query: 3658 ISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKS 3717
              + KN +    D+K     N I++ ++   S I    E   +L+ +  E +  +   K 
Sbjct: 1020 DLEAKNTQTLTADVK----DNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKE 1075

Query: 3718 SMKLTN--------LCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVS 3769
            ++++T         L   L       +  +  A K K G L      L  +     +  S
Sbjct: 1076 NIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIK-KEGELSRTCDRLA-EVEEKLKEKS 1133

Query: 3770 SAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKS----LFRHLLH 3825
                  +  L NV E     QKK  + EN+   K+ +  K +TL+  ++    L + L  
Sbjct: 1134 QQLQEKQQQLLNVQEEMSEMQKKINEIENL---KNELKNKELTLEHMETERLELAQKLNE 1190

Query: 3826 GKEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSS 3885
              E  +S  K  K+ +E + +    ++ L               I+E+   G+       
Sbjct: 1191 NYEEVKSITKERKVLKELQKSFETERDHL------------RGYIREIEATGL------- 1231

Query: 3886 STQQELSDT---MEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQ 3942
             T++EL      +++ ++ ID+   S+ +        +D     LEK  H+K   L+ + 
Sbjct: 1232 QTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD-----LEK-SHTK---LQEEI 1282

Query: 3943 PSIFQELEL--NIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSS 4000
            P + +E EL  N+KE     +   E+E+ ++   +      +++      E  R+++   
Sbjct: 1283 PVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARI------EMERLRLNEK 1336

Query: 4001 FSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQ 4060
            F     QES +  K+  ++   DN+  ++K+ALE    + +    E +  +++ +S   Q
Sbjct: 1337 F-----QESQEEIKSLTKE--RDNLK-TIKEALEVKHDQLKEHIRETLAKIQESQSKQEQ 1388

Query: 4061 GIQLDIKEQE-----KRIEHIKGEPSVLLTNACASIPSPSHLQL--DTRREKAEYVTEIT 4113
             + +  K+ E       +E  K + S LL      +     LQ   D  +  A+   ++ 
Sbjct: 1389 SLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQ 1448

Query: 4114 RYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPED 4173
            R  L E+   +S +  E    + +K   T +  K   +   KE +E     + ++   E 
Sbjct: 1449 R--LQEVLQSESDQLKENIKEIVAKHLETEEELKVA-HCCLKEQEETINELRVNLSEKET 1505

Query: 4174 KGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQ 4233
            +    +K L             ++ + Q + +E  E EEQ    +    QEKV+  + +Q
Sbjct: 1506 EISTIQKQLEA-----------INDKLQNKIQEIYEKEEQFNIKQISEVQEKVN--ELKQ 1552

Query: 4234 GKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQ 4293
             K +H   +      +  +  ++     E +  + + +     +       +IE ++ ++
Sbjct: 1553 FK-EHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKE 1611

Query: 4294 GIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMH 4353
                        Q+      K   V    +   E++  K+  + ++          +L +
Sbjct: 1612 NTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQK---------LNLEN 1662

Query: 4354 PEDKDLKGKKALSQNLPLNPKEPGKRDG--EGQEQGKEDGEGEEQGNRDGETEEQQQADG 4411
             E ++++  + L +NL        +RD     +E  K + +  ++  R+  T + +    
Sbjct: 1663 IETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLE---- 1718

Query: 4412 VGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKS 4471
                         KQE +  +H+          L   +E  + L+GI+   T ++   + 
Sbjct: 1719 -------------KQEELKIVHM---------HLKEHQETIDKLRGIVSEKTNEISNMQK 1756

Query: 4472 FDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPH 4531
                         ++ SND    Q+ K Q+E+     ++  ++ + + TI          
Sbjct: 1757 ------------DLEHSNDALKAQDLKIQEEL----RIAHMHLKEQQETI---------- 1790

Query: 4532 TLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKK--EEQ 4589
                      K R +++   +KL ++Q+              S+ KL ++    K  E Q
Sbjct: 1791 ---------DKLRGIVSEKTDKLSNMQKDLEN----------SNAKLQEKIQELKANEHQ 1831

Query: 4590 GVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPE 4649
             +T          + ++T K    +  L     D + T  +++++ +  N+++K   + E
Sbjct: 1832 LITLK-------KDVNETQKKVSEMEQLKKQIKDQSLT--LSKLEIENLNLAQKLHENLE 1882

Query: 4650 YI-AVKAEKSPLSHILKTKEL---QVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLE 4705
             + +V  E+  L  + +T +L   Q+  S Q  KA++ E++  +   KT   ++      
Sbjct: 1883 EMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQEL---KTARMLSKEHKET 1939

Query: 4706 LDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVS 4765
            +D ++E+  E  I  S     +IQ+ L   +    K  + L KKE QLL  KED   +  
Sbjct: 1940 VDKLREKISEKTIQIS-----DIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHK 1994

Query: 4766 MHGLMHPNGAVFKAKTSAPPQV----FSITE--HSPL------SKRKEPQWGMKERAGQK 4813
                M      F+A+  +   V    F +T+  H  L      +K ++    +KE    +
Sbjct: 1995 KINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKME 2054

Query: 4814 QDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANS-NEGISSHKVILK 4872
            +D+      I T          +H+  P +  L      G+  L  S  E  S  K +LK
Sbjct: 2055 RDQ-----FIATLREMIARDRQNHQVKPEKRLL----SDGQQHLTESLREKCSRIKELLK 2105

Query: 4873 ANQQM-PYKEAKDRVKIEGREGRILPKRIHLRAEA---LPL-------ALLCNGKNYSLH 4921
               +M  + E  +R+ ++  +     K + +R +A   LP         L    +  S+ 
Sbjct: 2106 RYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSME 2165

Query: 4922 I------------------EEQGEGVQESKKE--PGVVPRKSASFPPPPFYLNCDTRRNE 4961
                               EEQ E + + + +    V  +K           +CD    E
Sbjct: 2166 FHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRE 2225

Query: 4962 --------------KEGTLGKTQFSFPPLKIQ-DSSDSGKKAYTESLHGYTLSNSKGPVQ 5006
                          +E     ++  FP +K +     S +K  T+ L  +   N++  ++
Sbjct: 2226 LRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWL--NTRFDIE 2283

Query: 5007 PTAQGEEKGGLRIDMEDK--------MLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRK 5058
                G +K   RI   +         ++ + T+ + +   +S          K  EQ  K
Sbjct: 2284 KLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATIS----------KEWEQDLK 2333

Query: 5059 IQEDKNKQV-KGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIA 5117
              ++KN+++ K   ++ TSL +   +   T + +   +      L   + +E  ++   A
Sbjct: 2334 SLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEA 2393

Query: 5118 CPEATHG-----------ELSSDVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKK 5166
               A H            E+++D+       + +  K  EK  +   VL  +K+ L AK 
Sbjct: 2394 KESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQ-DKVALGAKP 2452

Query: 5167 SPVLHTHSFSDLQWKTREQEEEKVQKVK------SGPGVMLSKSPSRSSPLHLNVNTGFQ 5220
                +     DL+ K  + + EK++  K      S     +         L  N+    Q
Sbjct: 2453 ----YKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQ 2508

Query: 5221 EESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVSQNKEEDDVQIVSI 5280
             +   +++  + P  +    P T GG     I  +    + K +H+   KE   +     
Sbjct: 2509 AQDTSVISEHTDP--QPSNKPLTCGGG--SGIVQNTKALILKSEHIRLEKEISKL----- 2559

Query: 5281 LIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEMLRLKRPILRRISHI 5340
                K Q E++ + + E                  L    HL NE+   K   L+R +H 
Sbjct: 2560 ----KQQNEQLIKQKNE-----------------LLSNNQHLSNEVKTWKERTLKREAHK 2598

Query: 5341 GETVHRESVVGDIPKDVKNEKQHIP-QKEERNQKKIIDMRGTDITLKSKKSPRSC 5394
              T         +      +KQ  P Q +ERN +  +           K+SP+SC
Sbjct: 2599 QVTCENSPKSPKVTGTASKKKQITPSQCKERNLQDPV----------PKESPKSC 2643



 Score = 48.9 bits (115), Expect = 2e-04
 Identities = 125/665 (18%), Positives = 258/665 (38%), Gaps = 91/665 (13%)

Query: 5935 EEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHKARTANLE 5994
            +E+ +TD   NI +           T+  +E    +G    L  Q+E     K      E
Sbjct: 1066 KEQLKTDLKENIEM-----------TIENQEELRLLGDE--LKKQQEIVAQEKNHAIKKE 1112

Query: 5995 KERGRMDTSSSAHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQ 6054
             E  R     +     L  K+++ Q K Q + + +     MQK+  E+E  N K  ++ +
Sbjct: 1113 GELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIE--NLKNELKNK 1170

Query: 6055 KL-FQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITG 6113
            +L  +    +       L+   ++ K     R + +EL   + T +       + +  TG
Sbjct: 1171 ELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG 1230

Query: 6114 RGTPSNRKKLEYDVK--LKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLE--REKRI 6169
              T    K     +K   + I    + VS    + ++   +   HT  +  +    E++ 
Sbjct: 1231 LQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQE 1290

Query: 6170 CLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEANL 6229
             LP  +E S     M++ + LT    EQ+ T            D   + ++   +   N 
Sbjct: 1291 LLPNVKEVSETQETMNELELLT----EQSTTK-----------DSTTLARIEMERLRLNE 1335

Query: 6230 RSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDPKL 6289
            + + +++ +K+ TKER     ++  I +  +++  + +E I + +    E  S  E    
Sbjct: 1336 KFQESQEEIKSLTKER----DNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLN 1391

Query: 6290 PKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEATKA 6349
             K++D        TT+ V + + F    P    +   E++++  S   +           
Sbjct: 1392 MKEKDNE------TTKIVSEMEQFK---PKDSALLRIEIEMLGLSKRLQE---------- 1432

Query: 6350 ISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQFT 6409
             S  ++K++ ++K    +L  +   + D LK          + T    K  H  L EQ  
Sbjct: 1433 -SHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ-- 1489

Query: 6410 PKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSRHKTMNFM 6469
             +  N+L  +L  K  EI         +K L+  N   +  I +      Y + +  N  
Sbjct: 1490 EETINELRVNLSEKETEI------STIQKQLEAINDKLQNKIQE-----IYEKEEQFNIK 1538

Query: 6470 SL----EGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITKLQSINKLENGTSA 6525
             +    E  + ++   +H+  KDS L S +++ ++++++  +E+  ++Q + K +     
Sbjct: 1539 QISEVQEKVNELKQFKEHRKAKDSALQS-IESKMLELTNRLQESQEEIQIMIKEKEEMKR 1597

Query: 6526 VTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRESYAMTSAHERKKPL 6585
            V  A +      ++   +KE  K ++    K  E Q K +     +   MT+ +E ++ +
Sbjct: 1598 VQEALQ------IERDQLKENTKEIV---AKMKESQEKEY-----QFLKMTAVNETQEKM 1643

Query: 6586 SNCIH 6590
                H
Sbjct: 1644 CEIEH 1648



 Score = 48.1 bits (113), Expect = 3e-04
 Identities = 136/676 (20%), Positives = 266/676 (39%), Gaps = 100/676 (14%)

Query: 5932 GDLEEKHQTD---ANTNINLEQKKLEMDNDSTVNQK-EGKLKIGTNRALHLQEEKTEMHK 5987
            G LEE  +T    A T  N +    E  N  T++   E K K+       + EE   M++
Sbjct: 793  GLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKM-------VLEENERMNQ 845

Query: 5988 ARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELE-ASN 6046
                NL KE  + D+S  A    LS K +E Q KT+ +  R N    M++ K++LE   +
Sbjct: 846  -EIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNE---MEQLKEQLENRDS 901

Query: 6047 AKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIP 6106
              Q+++ +K      L      V    + KD      ++ L+  L  +   +K   H   
Sbjct: 902  TLQTVEREKTLITEKLQQTLEEVKTLTQEKDD-----LKQLQESLQIERDQLKSDIHDTV 956

Query: 6107 QMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLERE 6166
             M NI  +    N         L+++    + ++ +  + +S  + R+ H +  T   ++
Sbjct: 957  NM-NIDTQEQLRN--------ALESLKQHQETINTLKSK-ISEEVSRNLHMEENTGETKD 1006

Query: 6167 KRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSE 6226
                  +FQ+K     +  K+D       E   T T+  D +   + +QQ +K+ ++  E
Sbjct: 1007 ------EFQQKMVGIDK--KQDL------EAKNTQTLTADVKDNEIIEQQ-RKIFSLIQE 1051

Query: 6227 ANLRSEM------NKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTEC 6280
             N   +M       K+ LK   KE I        I  + +LR++  E K  + I+   + 
Sbjct: 1052 KNELQQMLESVIAEKEQLKTDLKENI-----EMTIENQEELRLLGDELKKQQEIVAQEKN 1106

Query: 6281 PSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHL 6340
             ++ ++ +L +  D+   V +   +K QQ            Q K  ++  V +   +E  
Sbjct: 1107 HAIKKEGELSRTCDRLAEVEEKLKEKSQQL-----------QEKQQQLLNVQEEM-SEMQ 1154

Query: 6341 LPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQ 6400
              I E     +E + K +  + + +++L+  Q             E  + + +    +  
Sbjct: 1155 KKINEIENLKNELKNKELTLEHMETERLELAQKLN----------ENYEEVKSITKERKV 1204

Query: 6401 HKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFY 6460
             K L + F  +       HL     EI+   +    ++ L++ + + K      +  R  
Sbjct: 1205 LKELQKSFETER-----DHLRGYIREIEATGL--QTKEELKIAHIHLKEHQETIDELRRS 1257

Query: 6461 SRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVS--SDSEETITKLQSINK 6518
               KT   ++ +  +     S  K Q++ P+    + L+ +V   S+++ET+ +L+ + +
Sbjct: 1258 VSEKTAQIINTQDLE----KSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTE 1313

Query: 6519 LENGTSAVTSA----SEMLLPHTLQNHSVKEKGKLLMHFSVKT----LEIQMKAFPRIVR 6570
                  + T A      + L    Q    + K       ++KT    LE++       +R
Sbjct: 1314 QSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIR 1373

Query: 6571 ESYAMTSAHERKKPLS 6586
            E+ A     + K+  S
Sbjct: 1374 ETLAKIQESQSKQEQS 1389



 Score = 45.4 bits (106), Expect = 0.002
 Identities = 314/1666 (18%), Positives = 635/1666 (38%), Gaps = 278/1666 (16%)

Query: 1161 NHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQ--DEVKGVKETLPKAVLHDSC 1218
            ++  ++  +EE +++ +EK      E  E +   D ++Q   E+  +K  +  A ++   
Sbjct: 513  DYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVY--- 569

Query: 1219 NLGLDAHLEKEIKTEKEMHQPIPFTETIIES--VVSPIMELSHA----ENVKSTQKTQTD 1272
            N  L+  L  +++  +E    I   +  I+S  + +  M+LS++    E+ K  ++T  D
Sbjct: 570  NQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFD 629

Query: 1273 CKCTA-DSETPSPI--SGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLP 1329
             +  A D++  S    S    + + + +   +Y               A++K ++  DL 
Sbjct: 630  AETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQV--DLE 687

Query: 1330 ATSPETFNYCTPVLS-----------CSKVMKKRVTFA---LTTSTAKPKCVNTKAVKPS 1375
                  FN  T + S           C+  ++ ++T     L     + + +  + +   
Sbjct: 688  KELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVIL-- 745

Query: 1376 ISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQ 1435
            +SE  S+ S  ++   + + K ++++            + +    +L  E     S++ Q
Sbjct: 746  LSELKSLPSEVERLRKEIQDKSEELH------------IITSEKDKLFSEVVHKESRV-Q 792

Query: 1436 G--ETADKTYTDVFAKNSISHDREEKLQDGK------EEEHKVLLEAAPQLSQHLGSEAG 1487
            G  E   KT  D+    S     +++ Q+ K      E+++K++LE   +++Q + + + 
Sbjct: 793  GLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSK 852

Query: 1488 QMKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEN 1547
            + ++     D  L  L  EL    Q LQ +T   Q  L    Q+     E+L+  + T  
Sbjct: 853  EAQKF----DSSLGALKTELSYKTQELQEKTREVQERLNEMEQL----KEQLENRDST-- 902

Query: 1548 DIKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFT 1607
                           LQ +E    LI    Q+  E VK+   L Q      Q+Q      
Sbjct: 903  ---------------LQTVEREKTLITEKLQQTLEEVKT---LTQEKDDLKQLQESLQIE 944

Query: 1608 QTILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSS---HQKE 1664
            +  LKS    T++     + +       LK  +  ++ +     +  IS + S   H +E
Sbjct: 945  RDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTL-----KSKISEEVSRNLHMEE 999

Query: 1665 QAGGTEKK-ETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNI 1723
              G T+ + +  + G         K T+ L   +D+K        II+ ++   S +   
Sbjct: 1000 NTGETKDEFQQKMVGIDKKQDLEAKNTQTLT--ADVKDNE-----IIEQQRKIFSLI--- 1049

Query: 1724 RAGAGPKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKR 1783
                  + + EL   L + + E  Q K  + E    + MT  I    ++    D L++++
Sbjct: 1050 ------QEKNELQQMLESVIAEKEQLKTDLKEN---IEMT--IENQEELRLLGDELKKQQ 1098

Query: 1784 LSSTQVKQDTSPHEDSITSR-----DIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRS 1838
                Q K      E  ++       +++E L +  +Q + KQ+ LL V  +  +      
Sbjct: 1099 EIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEM----- 1153

Query: 1839 GQGKDLDFHKLENQGSRKILFVTKQDVPQQLQPAEPIQR--EETKKCLQTQNGTICTVNS 1896
             Q K  +   L+N+   K L +   +  ++L+ A+ +    EE K        +I     
Sbjct: 1154 -QKKINEIENLKNELKNKELTLEHMET-ERLELAQKLNENYEEVK--------SITKERK 1203

Query: 1897 KLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFN------KDLQATVL 1950
             L  L+       + L G I+           E   +G   K E        K+ Q T+ 
Sbjct: 1204 VLKELQKSFETERDHLRGYIR-----------EIEATGLQTKEELKIAHIHLKEHQETID 1252

Query: 1951 ELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTH 2010
            EL++S     AQ  N  D+E   +                   L E +P          H
Sbjct: 1253 ELRRSVSEKTAQIINTQDLEKSHTK------------------LQEEIPVL--------H 1286

Query: 2011 QMKDPDP-CKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEG 2069
            + ++  P  K  SE +        ++ +   T+Q T    T L  I    ++ +   QE 
Sbjct: 1287 EEQELLPNVKEVSETQE------TMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQES 1340

Query: 2070 IKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPR--RKWDSSISEKTAWNQKNLQTVLKPL 2127
                E +K+   +    K      +   D+     R+  + I E  +  +++L    K  
Sbjct: 1341 ---QEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDN 1397

Query: 2128 DFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHR 2187
            + + ++S               +   PK   L   ++ +L L   ++   E+H + K   
Sbjct: 1398 ETTKIVSE-------------MEQFKPKDSALLRIEIEMLGLSKRLQ---ESHDEMKS-- 1439

Query: 2188 FKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNT----AARCILSNRTRRQN- 2242
                 K K     + E L S ++  K    K ++ K L        A C L  +    N 
Sbjct: 1440 ---VAKEKDDLQRLQEVLQSESDQLKENI-KEIVAKHLETEEELKVAHCCLKEQEETINE 1495

Query: 2243 LDGHITEEKEEV---QENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEIIFNAKCLT- 2298
            L  +++E++ E+   Q+ + AI             + K Q    ++ EKE  FN K ++ 
Sbjct: 1496 LRVNLSEKETEISTIQKQLEAI-------------NDKLQNKIQEIYEKEEQFNIKQISE 1542

Query: 2299 MKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ-----EN 2353
            ++EK + + Q         ++HRK   S L+++ + K  E    + E +EE+Q     + 
Sbjct: 1543 VQEKVNELKQF--------KEHRKAKDSALQSIES-KMLELTNRLQESQEEIQIMIKEKE 1593

Query: 2354 SPATFLGPLDFFMPVLSD-SKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISGQF 2412
                    L      L + +K  +  ++ S+ K     K   + E +  + +I  +  QF
Sbjct: 1594 EMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF 1653

Query: 2413 TTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKR-QSGFQTEIDMRISGL 2471
             T+ +  LE N++T+   + Q   + +      S T +  D++  +   + E D     L
Sbjct: 1654 ETQ-KLNLE-NIETENIRLTQ--ILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENL 1709

Query: 2472 SHTQPTQIESLAE------GIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDP 2525
              T    +E   E       +  + + IDK R    +   K ++  + ++  EH    D 
Sbjct: 1710 RETITRDLEKQEELKIVHMHLKEHQETIDKLRG---IVSEKTNEISNMQKDLEH--SNDA 1764

Query: 2526 FYAENFMANTYLR-KDRHLGKSEDV------LLGETFFSKSQIYKGNSEKNVKIEKNKNG 2578
              A++      LR    HL + ++       ++ E     S + K     N K+++    
Sbjct: 1765 LKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQE 1824

Query: 2579 KESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLK-ENAFCNLAAIVPDSVG 2637
             ++ +  L  ++K  N  +   +  + +  +   Q++  S L+ EN   NLA  + +++ 
Sbjct: 1825 LKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIEN--LNLAQKLHENLE 1882

Query: 2638 RHSPASEE---MKRQNGRLKM-ADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQ 2693
                  +E   ++R    LK+  D+     +  +A+   + Q   TA   +   +KE   
Sbjct: 1883 EMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTA-RMLSKEHKETVD 1941

Query: 2694 NFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKE 2739
              + + +E  + + D +  ++ +++   + +   +   LQ+   KE
Sbjct: 1942 KLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKE 1987



 Score = 44.3 bits (103), Expect = 0.004
 Identities = 164/869 (18%), Positives = 325/869 (37%), Gaps = 141/869 (16%)

Query: 3980 PYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQK 4039
            PY  V  +  +EA+  + R        Q    + +T  +    D ++  +++  + +LQK
Sbjct: 333  PY--VNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEE--KDLLQK 388

Query: 4040 EQRQKMEKIRALKKMKSSISQGIQLDIKEQEKR--------IEHIKGEPSVLLTNACASI 4091
             Q +K+E +  +    SS++  +Q ++K + KR        I  +K        N   +I
Sbjct: 389  VQNEKIENLTRMLVTSSSLT--LQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNI 446

Query: 4092 PSPSH-LQLDTRREKAEYV---TEITRYYLPELSHQKSSEAGE-------KADGVASKGD 4140
             + +H L ++  RE  E V   +++    L  LS  + + A +       +++  + + D
Sbjct: 447  TTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRAD 506

Query: 4141 ITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEA 4200
                V   +    +KE+ E+K+  K D+   E    K KK     L         + + A
Sbjct: 507  YDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHA 566

Query: 4201 QEQGKEDREGEEQG-------KEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQ 4253
             E   +D E E          KED+    QE +D +  E  KMD     +   D   ++Q
Sbjct: 567  -EVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQ 625

Query: 4254 GKMDGD--------------------KNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQ 4293
               D +                    K + + +   Y    + +  Y   +++E ++  Q
Sbjct: 626  TLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLY--QSQLEAKKKMQ 683

Query: 4294 GIIRPGILQPRHQKSSETGKKANGVPSE-----------GDSASEVQKAKDYMQQKEEDE 4342
              +   +    ++ +  T      VP +            D   E+ K  +  +   E+ 
Sbjct: 684  VDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEV 743

Query: 4343 VKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGE-GQEQGKEDGEGEEQGNRDG 4401
            + +S  K L    ++  K  +  S+ L +   E  K   E   ++ +  G  EE G    
Sbjct: 744  ILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIG---- 799

Query: 4402 ETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKS 4461
                 +  D + T Q        + +    LH+  E       L   +   +++  + K 
Sbjct: 800  -----KTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMV-LEENERMNQEIVNLSKE 853

Query: 4462 ATL------QLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKE-----VDRGKTVS 4510
            A         L+ + S+   ++        +  N+++ ++E    ++     V+R KT+ 
Sbjct: 854  AQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLI 913

Query: 4511 VDYIMQ------------------PEGTIFEAEQL--SLPHTLNIPGSSGSKTREVLTNI 4550
             + + Q                   E    E +QL   +  T+N+       T+E L N 
Sbjct: 914  TEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNM----NIDTQEQLRNA 969

Query: 4551 KEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKL 4610
             E L+  QE  + L   ++     +  +++ T   K+E       +     +E+ +T   
Sbjct: 970  LESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNT--- 1026

Query: 4611 KYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQ 4670
                     +T D    + + Q +K  + I EK+ +     +V AEK  L   LK + ++
Sbjct: 1027 -------QTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLK-ENIE 1078

Query: 4671 VNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQE 4730
            + I  Q E    G+      L K    V      E +   ++EGE  ++R+     E++E
Sbjct: 1079 MTIENQEELRLLGDE-----LKKQQEIVAQ----EKNHAIKKEGE--LSRTCDRLAEVEE 1127

Query: 4731 SLPSRQTAPTKPTESLVKKEKQLLPQKED 4759
             L  +       ++ L +K++QLL  +E+
Sbjct: 1128 KLKEK-------SQQLQEKQQQLLNVQEE 1149



 Score = 41.6 bits (96), Expect = 0.028
 Identities = 214/1185 (18%), Positives = 443/1185 (37%), Gaps = 174/1185 (14%)

Query: 3668 AMDMKR----IKSPNIILKPRKSSLSHILSIKEFPLLL--DIIKQEGKMQEGKGKSSMKL 3721
            A+D KR    ++S N+ LK +   L+      E  + L    ++ + KMQ    K     
Sbjct: 634  ALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSA 693

Query: 3722 TNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSN 3781
             N  T L SL             +  G +      L  +   N       E++ R+ +  
Sbjct: 694  FNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEEN-------EAL-REEVIL 745

Query: 3782 VIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKM-- 3839
            + E K  P + +  R+ I D  + +    I    K  LF  ++H  +  R    LE++  
Sbjct: 746  LSELKSLPSEVERLRKEIQDKSEELH---IITSEKDKLFSEVVH--KESRVQGLLEEIGK 800

Query: 3840 TQED----ESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTM 3895
            T++D    +SN      +         H+++  + K V          +    QE+ + +
Sbjct: 801  TKDDLATTQSNYKSTDQEF--QNFKTLHMDFEQKYKMVLEE-------NERMNQEIVN-L 850

Query: 3896 EKCEQPIDDSLSSIE-----KAKHMPQKDKDRVEK----------------ALEKIMHSK 3934
             K  Q  D SL +++     K + + +K ++  E+                 L+ +   K
Sbjct: 851  SKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREK 910

Query: 3935 RIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMR 3994
             +  E  Q ++ +E++   +EK    Q  + ++I      S      +    I+ +E +R
Sbjct: 911  TLITEKLQQTL-EEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNM--NIDTQEQLR 967

Query: 3995 IKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQ-RQKMEKIRALKK 4053
              + S      L++  +T  T   K IS+ +S ++     +   K++ +QKM  I   + 
Sbjct: 968  NALES------LKQHQETINTLKSK-ISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD 1020

Query: 4054 MKSSISQGIQLDIK-----EQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRR--EKA 4106
            +++  +Q +  D+K     EQ+++I  +  E + L     + I     L+ D +   E  
Sbjct: 1021 LEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMT 1080

Query: 4107 EYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKV-------QKAKDYMQQKEDDE 4159
                E  R    EL  Q+   A EK   +  +G+++          +K K+  QQ ++ +
Sbjct: 1081 IENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQ 1140

Query: 4160 VKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRR 4219
             ++   ++ M    K +   + L  +L         M+ E  E  ++  E  E+ K   +
Sbjct: 1141 QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITK 1200

Query: 4220 GAGQEKVDREDKE--QGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSL 4277
               + KV +E ++  + + DH     ++ +  G++         E+ ++  ++L  +   
Sbjct: 1201 ---ERKVLKELQKSFETERDHLRGYIREIEATGLQ-------TKEELKIAHIHLKEHQET 1250

Query: 4278 THYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQ 4337
               I + R    E    II    L+  H K  E     +       +  EV + ++ M +
Sbjct: 1251 ---IDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNE 1307

Query: 4338 ----KEEDEVKISAEKDLMHPEDKDLKGKKALSQN--LPLNPKEPGKRDGEGQEQGKEDG 4391
                 E+   K S     +  E   L  K   SQ     L  +    +  +   + K D 
Sbjct: 1308 LELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQ 1367

Query: 4392 EGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYEL------ 4445
              E       + +E Q         +++D   +K  + +    P +S+L   E+      
Sbjct: 1368 LKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLS 1427

Query: 4446 NTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDR 4505
               +E  ++++ + K      R Q+   +      ++     +  ++T +E K       
Sbjct: 1428 KRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELK------- 1480

Query: 4506 GKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELD 4565
               V+   + + E TI E  +++L        +   +   +   ++ K++ + E++ + +
Sbjct: 1481 ---VAHCCLKEQEETINEL-RVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFN 1536

Query: 4566 VFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSN 4625
            +             K+ +  +E+    + F     H ++ D+  L+   S + ++T    
Sbjct: 1537 I-------------KQISEVQEKVNELKQF---KEHRKAKDSA-LQSIESKMLELTNRLQ 1579

Query: 4626 RTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGEV 4685
             ++   QI      I EK  M     A++ E+  L     TKE+   + +  EK  +   
Sbjct: 1580 ESQEEIQIM-----IKEKEEMKRVQEALQIERDQLKE--NTKEIVAKMKESQEKEYQ--- 1629

Query: 4686 EIVVLLSKTCPFVTSSAFLELDSIKE------------EEGEPRITRSFMPHLEIQESLP 4733
                 L  T    T     E++ +KE            E    R+T+    +LE   S+ 
Sbjct: 1630 ----FLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSV- 1684

Query: 4734 SRQTAPTKPTESLVKKEKQLLP-----------QKEDRVQTVSMH 4767
            +++    +  E  +K E+  L            +K++ ++ V MH
Sbjct: 1685 TKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH 1729



 Score = 37.4 bits (85), Expect = 0.53
 Identities = 72/357 (20%), Positives = 140/357 (39%), Gaps = 61/357 (17%)

Query: 652  KESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEA----------ISKPMQKL 701
            KE+L+++IT+       +       K   +H+ +H+ ++++           IS   + L
Sbjct: 1706 KENLRETITR-------DLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDL 1758

Query: 702  VSSPEMESNNRMKIQEDLQSSENSHLQLSNGEE--------LPTSTPKT---QRCFPREN 750
              S +      +KIQE+L+ +   H+ L   +E        +   T K    Q+     N
Sbjct: 1759 EHSNDALKAQDLKIQEELRIA---HMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSN 1815

Query: 751  TQKQKDFLELVLELSNVGLLISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTE 810
             + Q+   EL      +  L    ++  K   E+E +K Q+  +S+ L  SK  I N+  
Sbjct: 1816 AKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTL--SKLEIENLNL 1873

Query: 811  DSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRI 870
               L E+ E   +      N+ + +E           T+    D    S+ + KA  L I
Sbjct: 1874 AQKLHENLEEMKSVMKERDNLRRVEE-----------TLKLERDQLKESLQETKARDLEI 1922

Query: 871  IRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHL 930
                    K  ++  ++  +  + + +  + K  Q  D ++   ++  EL +  +    L
Sbjct: 1923 ----QQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQ---EL 1975

Query: 931  KQKPKYVKFQMEQISSGSSKAPNKEQ---EVQPQTLSTQTILENSPCPMMDPFQVEK 984
            ++K   +    E ++    K    EQ   + + Q LS Q++        MD FQ+ K
Sbjct: 1976 QKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSV-------RMDNFQLTK 2025



 Score = 36.2 bits (82), Expect = 1.2
 Identities = 149/830 (17%), Positives = 313/830 (37%), Gaps = 117/830 (14%)

Query: 318  QAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDR----NQHFVEV 373
            Q Q +N  +E   S+ + K +     ++ +K      T +  +++ L+     N+++ EV
Sbjct: 1140 QQQLLNVQEEM--SEMQKKINEIENLKNELKN--KELTLEHMETERLELAQKLNENYEEV 1195

Query: 374  PSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPNLV 433
             SI + +  +K L+       D H   +I     +    G  T     E  +  ++    
Sbjct: 1196 KSITKERKVLKELQKSFETERD-HLRGYIR----EIEATGLQT---KEELKIAHIHLKEH 1247

Query: 434  TEDMPQLRSVKAQGQQQIVSS---ELNQDSVYSSVPLL----STIKGQKNRRKTPDSKSK 486
             E + +LR   ++   QI+++   E +   +   +P+L      +   K   +T ++ ++
Sbjct: 1248 QETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNE 1307

Query: 487  LSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISV 546
            L L       K + T    ++         NE   ++  E K L + +D        + V
Sbjct: 1308 LELLTEQSTTKDSTTLARIEMERLRL----NEKFQESQEEIKSLTKERDNLKTIKEALEV 1363

Query: 547  SKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKE 606
                   +K + R+ L K+     K    L  + K  +T KI       +   S + + E
Sbjct: 1364 KH---DQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIE 1420

Query: 607  KEYDKENKRLKNISPKM---------LPQLEQSFMVNTVQLKAPCL-LVETNGKSKESLK 656
             E    +KRL+    +M         L +L++     + QLK     +V  + +++E LK
Sbjct: 1421 IEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELK 1480

Query: 657  DS--ITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMK 714
             +    + +   I E  V  S+K  +  I   +  LE    K   K+    E E    +K
Sbjct: 1481 VAHCCLKEQEETINELRVNLSEK--ETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIK 1538

Query: 715  IQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISPG 774
               ++Q   N   Q     +   S  ++      E T + ++  E +             
Sbjct: 1539 QISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEI------------- 1585

Query: 775  SKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGS-------N 827
              M K  EE++ ++  +  E   LKE+   I+   ++S  +E + L+    +        
Sbjct: 1586 QIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCE 1645

Query: 828  ITNMHQDKETSD------AFHSATYTTISQLPDTETHSISKAKAD------TLRIIR--- 872
            I ++ +  ET           +   T I      E  S++K + D      TL++ R   
Sbjct: 1646 IEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL 1705

Query: 873  -------LSHSASKQE--KLPDEKETQNAEYIDK--SCTFKKPQQCDRKEQEKEANSELT 921
                   ++    KQE  K+      ++ E IDK      +K  +    +++ E +++  
Sbjct: 1706 KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDAL 1765

Query: 922  QGFRFSI---------HLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILENS 972
            +     I         HLK++ + +      +S  + K  N +++++      Q  ++  
Sbjct: 1766 KAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQEL 1825

Query: 973  PCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNLQ 1032
                 +  Q+  +K+  +    + S  +        ++L + +L IE    +     NL+
Sbjct: 1826 KA---NEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLE 1882

Query: 1033 KTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKS 1082
            +     + +E+++++R    + L             +R ++K+ L ETK+
Sbjct: 1883 EM--KSVMKERDNLRRVEETLKL-------------ERDQLKESLQETKA 1917



 Score = 35.8 bits (81), Expect = 1.6
 Identities = 164/889 (18%), Positives = 345/889 (38%), Gaps = 169/889 (19%)

Query: 2237 RTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEIIFNAKC 2296
            +T ++ L+    + KE ++E +A I          +    K+   T  +SE E       
Sbjct: 1355 KTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEME------- 1407

Query: 2297 LTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRK--CQENHGHITEEEEEVQENS 2354
               K K S++ +I +I      K  ++    +K+V+  K   Q     +  E ++++EN 
Sbjct: 1408 -QFKPKDSALLRI-EIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI 1465

Query: 2355 PATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISGQFTT 2414
                   L+      ++ + ++    L E++  +N   + + EK+  IS I K       
Sbjct: 1466 KEIVAKHLE------TEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQK------- 1512

Query: 2415 KHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGLSH- 2473
               + +   L+ K++ +++ E              +  +IK+ S  Q +++       H 
Sbjct: 1513 -QLEAINDKLQNKIQEIYEKE--------------EQFNIKQISEVQEKVNELKQFKEHR 1557

Query: 2474 -TQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENFM 2532
              + + ++S+   +   ++ + + +    +    + ++E  +  QE L        EN  
Sbjct: 1558 KAKDSALQSIESKMLELTNRLQESQEEIQIM---IKEKEEMKRVQEALQIERDQLKEN-- 1612

Query: 2533 ANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEKS 2592
                + K +   + E   L  T  +++Q      EK  +IE  K   E+ K+ L  +E  
Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTAVNETQ------EKMCEIEHLKEQFETQKLNLENIETE 1666

Query: 2593 ---------DNCAELSEATD--DAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSP 2641
                     +N  E+   T   D + +  +   +    LKEN        + +++ R   
Sbjct: 1667 NIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKEN--------LRETITRDLE 1718

Query: 2642 ASEEMKRQNGRLKMADRSSPQGRPLQA-KQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKT 2700
              EE+K  +  LK    +  + R + + K + +S       +   SN+  + Q+ K Q+ 
Sbjct: 1719 KQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH---SNDALKAQDLKIQEE 1775

Query: 2701 E--AEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPK 2758
               A + L +Q+  I+                   I ++K  K ++ +   +     L +
Sbjct: 1776 LRIAHMHLKEQQETIDKLRG---------------IVSEKTDKLSNMQKDLENSNAKLQE 1820

Query: 2759 KQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLE 2818
            K QEL          N +  I+ K    KD  +T    S M   + ++K + +T+S+L E
Sbjct: 1821 KIQELKA--------NEHQLITLK----KDVNETQKKVSEMEQLKKQIKDQSLTLSKL-E 1867

Query: 2819 YGTASNKKELRGNIQQQKSFQLSKNAVHRV---LKAVYDS---------GYCVSSIKKLT 2866
                +  ++L  N+++ KS    ++ + RV   LK   D             +   ++L 
Sbjct: 1868 IENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELK 1927

Query: 2867 EVKMEKDKPKDRTCILPQPKLEKPLK--EMQRSLSGCTDMSSILRKQEQDIREKEQKHQS 2924
              +M   + K+    L +   EK ++  ++Q+ L    D    L+K+ Q++++KE +   
Sbjct: 1928 TARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDE---LQKKIQELQKKELQLLR 1984

Query: 2925 ISEDISQYY--IGPLRISSQQINYSSFDAPRIRTD------------EELEFLIAQRAK- 2969
            + ED++  +  I  +    +Q    +     +R D            EE+  +  +R + 
Sbjct: 1985 VKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDEL 2044

Query: 2970 ---------EKDVGIAKHSVSIPWERE-------------GSKRLDIPLNSKGQNIF--- 3004
                     E+D  IA     I  +R+             G + L   L  K   I    
Sbjct: 2045 RRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELL 2104

Query: 3005 --FTELDTSQQKTCQ-----EQELLKQEDISMTNLGSMACPIMEPLHLE 3046
              ++E+D   +   +     E+E+  Q+++SM    +++ P ++  H+E
Sbjct: 2105 KRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIE 2153



 Score = 34.3 bits (77), Expect = 4.5
 Identities = 240/1309 (18%), Positives = 503/1309 (38%), Gaps = 179/1309 (13%)

Query: 5054 EQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDA 5113
            EQK K+  ++N+++     +N   L+    KFD++ G        K    Q +++E  + 
Sbjct: 830  EQKYKMVLEENERMNQ-EIVN---LSKEAQKFDSSLGALKTELSYKTQELQEKTREVQE- 884

Query: 5114 GRIACPEATHGELSS------DVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAK-- 5165
             R+   E    +L +       V++ K  + +K ++  E+V  +T   D  K   ++   
Sbjct: 885  -RLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQI 943

Query: 5166 -----KSPVLHTHSFS-DLQWKTR------EQEEEKVQKVKSGPGVMLSKSPSRSSPLHL 5213
                 KS +  T + + D Q + R      +Q +E +  +KS     +S+  SR+  LH+
Sbjct: 944  ERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKS----KISEEVSRN--LHM 997

Query: 5214 NVNTG-----FQEESIPILTRPSFPLVKLQ-VSPDTEGGTCIRPIAGDILIYLQKGKHVS 5267
              NTG     FQ++ + I  +        Q ++ D +    I           Q+ K  S
Sbjct: 998  EENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIE----------QQRKIFS 1047

Query: 5268 QNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEML 5327
              +E++++Q +   +  + ++ K           L ++  +   +Q EL     LG+E+ 
Sbjct: 1048 LIQEKNELQQMLESVIAEKEQLKTD---------LKENIEMTIENQEELRL---LGDELK 1095

Query: 5328 RLKRPILRRISHI----GETVHRESVVGDIPKDVKNEKQHIPQKEER----------NQK 5373
            + +  + +  +H     GE       + ++ + +K + Q + +K+++           QK
Sbjct: 1096 KQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK 1155

Query: 5374 KIIDMRGTDITLKSKKSPRSCM-LHRTELHVNIGGQGRKEHEGQDKPPGMI-QRKMCILF 5431
            KI ++      LK+K+     M   R EL        +K +E  ++   +  +RK+    
Sbjct: 1156 KINEIENLKNELKNKELTLEHMETERLEL-------AQKLNENYEEVKSITKERKVLKEL 1208

Query: 5432 SKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRS 5491
             K   +     R    + E  G +T   L +    L + ++T D   RS   +  +   +
Sbjct: 1209 QKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINT 1268

Query: 5492 QKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSR 5551
            Q   +   K  +    +H ++  +  +  +   +E    +N+LE    +   +    L+R
Sbjct: 1269 QDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQE---TMNELELLTEQSTTKDSTTLAR 1325

Query: 5552 TFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVK 5611
              +        + +S  +    T         +  L V  +  K   R+++  + ++  K
Sbjct: 1326 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK 1385

Query: 5612 QAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIYFTGFGTIRS 5671
            Q EQ +   E + + T+  +  ++Q           ++  L L+ R ++ +       + 
Sbjct: 1386 Q-EQSLNMKEKDNE-TTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKE 1443

Query: 5672 G---KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGG--LEEDTEIMDNLNHKIS 5726
                +R + +   +  Q  +   E +   L   T +  K+    L+E  E ++ L   +S
Sbjct: 1444 KDDLQRLQEVLQSESDQLKENIKEIVAKHLE--TEEELKVAHCCLKEQEETINELRVNLS 1501

Query: 5727 PKASVSLIRKISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDKP-KE 5785
             K +   I  I K+L        N     + E Y  +++ + K   E+       K  KE
Sbjct: 1502 EKETE--ISTIQKQLEAINDKLQNK----IQEIYEKEEQFNIKQISEVQEKVNELKQFKE 1555

Query: 5786 DGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHK 5845
              ++ D   +    K+L             +TN       E Q ++ +K+ ++R +   +
Sbjct: 1556 HRKAKDSALQSIESKMLE------------LTNRLQESQEEIQIMIKEKEEMKRVQEALQ 1603

Query: 5846 TRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALL 5905
               + +         K K   E     K    L +  +      M EI+  K   +   L
Sbjct: 1604 IERDQLKENTKEIVAKMKESQE-----KEYQFLKMTAVNETQEKMCEIEHLKEQFETQKL 1658

Query: 5906 ISEQEEG----VLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTV 5961
              E  E     + + L ++L    +   +  DL    +T     + +E+ +L+ +   T+
Sbjct: 1659 NLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEET-----LKVERDQLKENLRETI 1713

Query: 5962 N---QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEES 6018
                +K+ +LKI     +HL+E +  + K R    EK     +          +LKA++ 
Sbjct: 1714 TRDLEKQEELKIVH---MHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDL 1770

Query: 6019 QMKTQV-ITH---RENSRLI-------------MQKQKKELEASNAKQSIQLQKLFQRNV 6061
            +++ ++ I H   +E    I             +   +K+LE SNAK   ++Q+L     
Sbjct: 1771 KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANE- 1829

Query: 6062 LDSFYSYVPLSPK-RKDQKGRLTIRDLKRELSTKYLT---MKIQNHPIPQMLNITGRGTP 6117
                +  + L     + QK    +  LK+++  + LT   ++I+N  + Q L+       
Sbjct: 1830 ----HQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMK 1885

Query: 6118 SNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLE-REKRICLPKFQE 6176
            S  K+ +   +++      +D        L  S+  +   D +   E +  R+   + +E
Sbjct: 1886 SVMKERDNLRRVEETLKLERD-------QLKESLQETKARDLEIQQELKTARMLSKEHKE 1938

Query: 6177 KSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEANL------R 6230
                  E     T+ I   +++   +  +  +     +++  +L  VK + N+       
Sbjct: 1939 TVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINE 1998

Query: 6231 SEMNKKYLKAQTKERIVPEHDVSRIIKK-----PDLRIIEQEEKILKRI 6274
             E  KK  +AQ         D  ++ KK      ++RI+ +E   L+RI
Sbjct: 1999 MEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRI 2047


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 114/597 (19%), Positives = 241/597 (40%), Gaps = 86/597 (14%)

Query: 3884 SSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQP 3943
            +S   +E   T    +   DD  + +E+     ++ + R+++ALE+              
Sbjct: 72   NSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALER-------------- 117

Query: 3944 SIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQ 4003
               +E +  I +                  AS+S LP  ++     E     K   S S+
Sbjct: 118  --QKEFDPTITD------------------ASLS-LPSRRMQNDTAENETTEKEEKSESR 156

Query: 4004 PNLQESSDTEKT--AYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQG 4061
                E  +TE    +Y+K       N  + A E+  +KE ++K E+    K  + SI + 
Sbjct: 157  QERYEIEETETVTKSYQK-------NDWRDAEEN--KKEDKEKEEE-EEEKPKRGSIGEN 206

Query: 4062 IQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELS 4121
             Q+++  +EK  E    E +V+++     I S    Q + R + ++           E+S
Sbjct: 207  -QVEVMVEEKTTE--SQEETVVMSLKNGQISSEEPKQEEEREQGSD-----------EIS 252

Query: 4122 HQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKE--DDEVKISAKKDIMHPEDKGLKAK 4179
            H +  E  +K    A +  +  + ++     Q K+  D+  +I A++     E +  +A+
Sbjct: 253  HHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAE 312

Query: 4180 KALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHE 4239
            +   + +    K   +  Q  +E+ K   E  ++ KE+ + A +E+   +++E+      
Sbjct: 313  E--RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEK----RA 366

Query: 4240 VEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPG 4299
             EE+Q+A     E+ K++  K  ++              H + +T+I+GE+ +Q I    
Sbjct: 367  AEERQRARAEEEEKAKVEEQKRNKQL---------EEKKHAMQETKIKGEKVEQKIEGKW 417

Query: 4300 ILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDL 4359
            +     +K+ E   +   +  +G+      +AK    Q+++   K    KD    +DK+ 
Sbjct: 418  V---NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEP 474

Query: 4360 KGKKALSQNLPLNPKEPGKRDGE---GQEQGKEDGEGEEQGNRDGETEEQQQADGV--GT 4414
            K +     +      E   ++GE    + +  E+      G    +T+E + A  V  G 
Sbjct: 475  KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGK 534

Query: 4415 EQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKS 4471
              E+    + + E+  F  L  +      EL   K+  E+ + +++    + +Q+++
Sbjct: 535  RLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA 591



 Score = 49.7 bits (117), Expect = 1e-04
 Identities = 83/407 (20%), Positives = 170/407 (41%), Gaps = 42/407 (10%)

Query: 3896 EKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKE 3955
            EK E+  D   +  E+A+ +  ++++R++   +K +  +R  +E ++ +  QE E    E
Sbjct: 255  EKMEEE-DKERAEAERAR-LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAE 312

Query: 3956 KGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKT 4015
            +  +++E+++        A+       +      EE  RIK     +    Q   + EK 
Sbjct: 313  ERERMREEEKR-------AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 365

Query: 4016 AYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEH 4075
            A E+          K  +E   QK  +Q  EK  A+++ K    +G +++ K + K +  
Sbjct: 366  AAEERQRARAEEEEKAKVEE--QKRNKQLEEKKHAMQETKI---KGEKVEQKIEGKWVNE 420

Query: 4076 IKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGV 4135
             K +   L T            ++  +REK +   +   +   E+  +K  +  E  + V
Sbjct: 421  KKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ--EDKPTFKKEEIKDEKIKKDKEPKEEV 478

Query: 4136 AS-----KGDITIKVQKAKDYMQQKEDDEVKIS-----AKKDIMHPE-----DKGLKAKK 4180
             S     KG   +K Q  +    + +  E   S     A  D    E     + G + ++
Sbjct: 479  KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 538

Query: 4181 ALSQDLPLNTKEPGKMDQEAQEQGKE----DREGEEQGK---EDRRGAGQEKVDR---ED 4230
               +     ++E  K+ Q+ QE   E     ++ EE+ K   E+ +   QE+ DR   E+
Sbjct: 539  LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 598

Query: 4231 KEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSL 4277
            +E+ ++  E+ E+++A+     Q   +   ++ ++    + P  SSL
Sbjct: 599  EEKRRLKEEI-ERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSL 644



 Score = 47.8 bits (112), Expect = 4e-04
 Identities = 111/594 (18%), Positives = 236/594 (39%), Gaps = 106/594 (17%)

Query: 4011 DTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQE 4070
            + E+ AY++   D+   + ++      Q+  RQK E+  +L ++   +    Q  + ++E
Sbjct: 21   EAERIAYQRN-DDDEEEAARERRRRARQERLRQKQEE-ESLGQVTDQVEVNAQNSVPDEE 78

Query: 4071 KRIE----HIKGEPSVLLTNACASIPSPSHLQLDTRREKA-EYVTEIT--------RYYL 4117
             +       ++G+         A        +L    E+  E+   IT        R   
Sbjct: 79   AKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQ 138

Query: 4118 PELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLK 4177
             + +  +++E  EK++    + +I       K Y Q+ +  + + + K+D    E++  K
Sbjct: 139  NDTAENETTEKEEKSESRQERYEIEETETVTKSY-QKNDWRDAEENKKEDKEKEEEEEEK 197

Query: 4178 AKKALSQDLPLNTKEPGKMDQEAQE-------QGKEDREGEEQGKEDRRGAGQ----EKV 4226
             K+    +  +      K  +  +E        G+   E  +Q +E  +G+ +    EK+
Sbjct: 198  PKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKM 257

Query: 4227 DREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRI 4286
            + EDKE+ + +    E ++ + +  EQ K   D+                        RI
Sbjct: 258  EEEDKERAEAERARLEAEERERIKAEQDKKIADER----------------------ARI 295

Query: 4287 EGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKIS 4346
            E EE           Q R ++ +E  ++            E ++A +  Q+ +E+E + +
Sbjct: 296  EAEE-------KAAAQERERREAEERERMR---------EEEKRAAEERQRIKEEEKRAA 339

Query: 4347 AEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGE---EQGNRDGET 4403
             E+  +  E+     K+A  +   +  KE  KR  E +++ + + E +   E+  R+ + 
Sbjct: 340  EERQRIKEEE-----KRAAEERQRI--KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQL 392

Query: 4404 EEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNT---RKEGEEDLQGIIK 4460
            EE++ A     ++ K  G K +Q+  +     +E      +L T   +K+GEE      K
Sbjct: 393  EEKKHA----MQETKIKGEKVEQK--IEGKWVNEKKAQEDKLQTAVLKKQGEE------K 440

Query: 4461 SATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEV----DRGKTVSVDYIMQ 4516
               +Q +++K  +        +F  +   D K  ++ +P++EV    DR K      +  
Sbjct: 441  GTKVQAKREKLQE-----DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKK--GFTEVKS 493

Query: 4517 PEGTIFEAEQLSLPHTLNIPGSSGS---KTREVLTNIK--EKLRHVQERKSELD 4565
              G     +     +T + PG   S   K  E    ++  ++L  ++ R+ E +
Sbjct: 494  QNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETE 547


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 58.2 bits (139), Expect = 3e-07
 Identities = 68/293 (23%), Positives = 118/293 (40%), Gaps = 60/293 (20%)

Query: 4144 KVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQ 4203
            K++   D M++  D   +  A+           K +  + +D   N K       EA   
Sbjct: 44   KMKTKSDMMEENIDTSAQAVAET----------KQEAVVEEDYNENAKNGEAKITEAPAS 93

Query: 4204 GKEDREGEEQGKEDRRGAGQEKVD------REDKEQGKMDHEVEEQQKADGVGIEQGKMD 4257
             KE  E +E+  ED    G EK +      + ++E  K D E + ++K      E GK D
Sbjct: 94   EKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKG-----EAGKED 148

Query: 4258 GDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANG 4317
             D+  +E                      +G+ED+ G  +         K  E GKK   
Sbjct: 149  KDEKGEE----------------------DGKEDKNGNEKG-----EDAKEKEDGKKGED 181

Query: 4318 VPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPG 4377
                G+   E  K +D   +KEE++ K +   D    ED   KG K   +++ +   E  
Sbjct: 182  GKGNGEDGKE--KGED---EKEEEDRKETG--DGKENEDGKEKGDKKEGKDVKVKEDEKE 234

Query: 4378 KRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVL 4430
            + DG+  E G E+  G+E+ +   E E +++      E ++ DG K + ++++
Sbjct: 235  REDGKEDEGGNEEEAGKEKEDLKEEEEGKEE-----DEIKEDDGKKEEPQSIV 282



 Score = 50.4 bits (119), Expect = 6e-05
 Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 18/157 (11%)

Query: 4325 ASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPK---EPGKRDG 4381
            A+EV+  ++  ++ EED+   + EK     EDKD KG++   ++   N K      K DG
Sbjct: 120  AAEVKNEEEDQKEDEEDQ---NEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDG 176

Query: 4382 EGQEQGKEDGE-GEEQGNRDGETEEQQQ-ADGVGTEQEKRDGHKSKQETVLFLHLPSESS 4439
            +  E GK +GE G+E+G  + E E++++  DG   E  K  G K + + V       E  
Sbjct: 177  KKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKE-- 234

Query: 4440 LTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGK 4476
                    R++G+ED  G  + A  +    K  + GK
Sbjct: 235  --------REDGKEDEGGNEEEAGKEKEDLKEEEEGK 263



 Score = 48.9 bits (115), Expect = 2e-04
 Identities = 50/220 (22%), Positives = 92/220 (41%), Gaps = 59/220 (26%)

Query: 4125 SSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQ 4184
            + + GEK + VA++          K+  + +++DE   + +K     EDK  K ++   +
Sbjct: 109  TEKGGEKKEAVAAE---------VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKE 159

Query: 4185 DLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQ 4244
            D   N K     ++E  ++G++ +   E GKE     G+++ + ED+           ++
Sbjct: 160  DKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKE----KGEDEKEEEDR-----------KE 204

Query: 4245 KADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPR 4304
              DG   E GK  GDK E +                  D +++ +E              
Sbjct: 205  TGDGKENEDGKEKGDKKEGK------------------DVKVKEDE-------------- 232

Query: 4305 HQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVK 4344
              K  E GK+  G  +E ++  E +  K+  + KEEDE+K
Sbjct: 233  --KEREDGKEDEG-GNEEEAGKEKEDLKEEEEGKEEDEIK 269



 Score = 47.0 bits (110), Expect = 7e-04
 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 33/149 (22%)

Query: 4122 HQKSSEAGEKADGVAS---KGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKA 4178
            ++K  +A EK DG      KG+     +K +D   +KE+++ K +   D    ED   K 
Sbjct: 164  NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGED---EKEEEDRKETG--DGKENEDGKEKG 218

Query: 4179 KKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDH 4238
             K   +D+ +      K D++ +E GKED  G E+       AG+EK D +++E+GK + 
Sbjct: 219  DKKEGKDVKV------KEDEKEREDGKEDEGGNEEE------AGKEKEDLKEEEEGKEED 266

Query: 4239 EVEEQQKADGVGIEQGKMDGDKNEQERVL 4267
            E++E              DG K E + ++
Sbjct: 267  EIKED-------------DGKKEEPQSIV 282


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 58.2 bits (139), Expect = 3e-07
 Identities = 194/989 (19%), Positives = 385/989 (38%), Gaps = 164/989 (16%)

Query: 3889 QELSDTMEKCE----QPIDDSLSSIEKAKHMPQKDKDRVE---KALEKIMHSKRIALEVK 3941
            +EL +  EK E    + ++ +LS+ +K +   +K K  ++   K +EK    +RI+L+ +
Sbjct: 399  EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 458

Query: 3942 QPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGE--EAMRIKMRS 3999
               + QE+ +++ +K  + Q  K  ++  K  A        K+ T E E  E M++ +  
Sbjct: 459  LSRVKQEV-VDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEK 517

Query: 4000 SFSQ--PNLQESSDTEKTAYE------KCISDNISNSVK-----------------KALE 4034
            S S+     QE    E  A E      K I     N ++                  +LE
Sbjct: 518  SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE 577

Query: 4035 SILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSP 4094
              LQ+ + Q  +    L+  K+  ++ I + +++ +  +E +K +   L T     +   
Sbjct: 578  KSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQ 637

Query: 4095 SHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQ 4154
               +++  REK E                +  E   K   +  +  I    +K  + +  
Sbjct: 638  YQTEMEKLREKCE----------------QEKETLLKDKEIIFQAHIEEMNEKTLEKLDV 681

Query: 4155 KEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQG 4214
            K+ +   +S++   +      LKA+  L ++L +   +  KM QE + +  E +   +Q 
Sbjct: 682  KQTELESLSSELSEV------LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQ 735

Query: 4215 KEDRRGAGQEKVDREDKE------------QGKMDHEVEEQQKADGVGIEQGKMDGDKNE 4262
             +      +  + R +K             + +  H  E Q   + +  +  + +G+  +
Sbjct: 736  VDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 795

Query: 4263 QERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEG 4322
                L ++  S  S TH     + +  E+Q   ++  +L    ++   T + A     + 
Sbjct: 796  ASAKLDVF-QSYQSATH----EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKK 850

Query: 4323 DSASEVQ----KAKDYMQQKE----EDEVKISA-----EKDLMHPEDKDLKGKKAL--SQ 4367
            D  +E+     + +D MQQ E    E E K+ +     E  L     +  + K+ L   +
Sbjct: 851  DVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKE 910

Query: 4368 NLPLNPKEPGKRDGEGQEQ---GKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKS 4424
            N+ L  +E  K++ E   Q    KED       N + ET+ + Q   +   ++K    K 
Sbjct: 911  NMILQMREGQKKEIEILTQKLSAKED--SIHILNEEYETKFKNQEKKMEKVKQKA---KE 965

Query: 4425 KQETVLFLHLPSESSL------TCYELNTRKE---------GEEDLQGIIKSAT-LQLRQ 4468
             QET+    L  E+ L      T  EL+ +++          + +  GI  + + L+  Q
Sbjct: 966  MQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQ 1025

Query: 4469 QKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLS 4528
            ++  ++    H +       NDV ++ E K  ++ +  + +    + + E  + E +Q  
Sbjct: 1026 KEQIESLTEVHRREL-----NDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI 1080

Query: 4529 LPHTLNIPGSSGSKTREVLTNIKEK-------LRHVQERKSELDVFLTIPSLSHCKLDKR 4581
            L     + G    +  + +T +KE+       L  +QE+  +      + SL+  +   +
Sbjct: 1081 L-----LFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAH--VNSLAQDETKLK 1133

Query: 4582 TAGKKEEQGVTRSFLPPSWHME---------SSDTGKLKYTLSYLNDITGDSNRTKYMAQ 4632
               +K E  + +S    ++  E           D  K+    S L   T D       + 
Sbjct: 1134 AHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLK--TTDEEFQSLKSS 1191

Query: 4633 IQKDKANISEKSVMH---PEYIAVK----AEKSPLSHILKTKELQVNISQQGEKA----- 4680
             +K   ++ +KS+      E +A++     +K+      KT EL +NIS     A     
Sbjct: 1192 HEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNEL-INISSSKTNAILSRI 1250

Query: 4681 ---QEGEVEI-VVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQ 4736
               Q    ++   LL KTC    S    +L  + EE+    I  SF       E   ++ 
Sbjct: 1251 SHCQHRTTKVKEALLIKTC--TVSELEAQLRQLTEEQNTLNI--SFQQATHQLEEKENQI 1306

Query: 4737 TAPTKPTESLVKKEKQLLPQKEDRVQTVS 4765
             +     ESLV +++ L  +  ++ Q  S
Sbjct: 1307 KSMKADIESLVTEKEALQKEGGNQQQAAS 1335



 Score = 57.8 bits (138), Expect = 4e-07
 Identities = 363/2018 (17%), Positives = 761/2018 (37%), Gaps = 314/2018 (15%)

Query: 2802 KQIKLKAKRITVSQLLEYGTASNKKELRGNIQQQKSFQLS--KNAVHRVLKAVYDS-GYC 2858
            K + +  K   ++QL +       K L   ++Q K   ++  K  +H  L+   +     
Sbjct: 334  KDLHMAEKTKLITQLRD------AKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL 387

Query: 2859 VSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIRE- 2917
             S IK++T    E  + K+++      +LEK L   Q++      + + + +Q + I + 
Sbjct: 388  RSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKT 447

Query: 2918 KEQKHQSISEDISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAK 2977
             E++  S+ +++S+            +     D  +  ++E++  L  Q+  EK++   +
Sbjct: 448  SEEERISLQQELSR------------VKQEVVDVMKKSSEEQIAKL--QKLHEKELARKE 493

Query: 2978 HSVSIPW---EREGSKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISMTNLGS 3034
              ++      ERE  +++ + L            +  QQ++   +EL  Q+   +T   +
Sbjct: 494  QELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESEN 553

Query: 3035 MACPIMEP--------LHLENTGKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQK 3086
                + +         L LE++ + + +E+   ++ ++ H+  ++     +I V  +  K
Sbjct: 554  KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHK 613

Query: 3087 FLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQAVNTARKENVTISES 3146
                + + Q      +K QV            ++ + K     +Q   T  K+   I ++
Sbjct: 614  TELESLKHQQDALWTEKLQVLKQQY-------QTEMEKLREKCEQEKETLLKDKEIIFQA 666

Query: 3147 FNENLWGKEQSKLDIT-LKSNRQKMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYI 3205
              E +  K   KLD+   +      + S+ L+ +H     + + ++L+     +  +L  
Sbjct: 667  HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHK---LEEELSVLKDQTDKMKQELEA 723

Query: 3206 ENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIH---LNIKGRKEHPQEST 3262
            +  +++   ++ + S +         HEV I   +    + I+   L +K R +H +E  
Sbjct: 724  KMDEQKNHHQQQVDSII-------KEHEVSIQRTEKALKDQINQLELLLKERDKHLKE-- 774

Query: 3263 HEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYK 3322
            H+A   ++   +                            +  G L    A+ +   +Y+
Sbjct: 775  HQAHVENLEADIK---------------------------RSEGELQQASAKLDVFQSYQ 807

Query: 3323 ALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQM-DVIVGYTQNSKK 3381
            +    A+H +T  ++   +  Q+KL  ++      LT Q  E   Q  DV      +  +
Sbjct: 808  S----ATHEQTKAYEEQLAQLQQKLLDLETERI-LLTKQVAEVEAQKKDVCTELDAHKIQ 862

Query: 3382 RQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLD 3441
             QDL++  +K            ++    QK   L Q       E+  E GN         
Sbjct: 863  VQDLMQQLEK------------QNSEMEQKVKSLTQVY-----ESKLEDGNKEQEQTKQI 905

Query: 3442 LFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKT-IKYASLLFPKGMKSSDG 3500
            L   + +    +   +  + +++ +   K+DS+  L   ++T  K       K  + +  
Sbjct: 906  LVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKE 965

Query: 3501 VQVF---DLISNNSSPKLRL-GKKIETQKANEKVQKEVCLPITLHSLSASMPILQESKGQ 3556
            +Q      L+   +  K  L    +E  +  ++   ++      +S   S  + +    Q
Sbjct: 966  MQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQ 1025

Query: 3557 KDSVEQVIRKGVICHKRRT----SKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVNV 3612
            K+ +E +       H+R      S W+K +        +     + +++Q     ++  +
Sbjct: 1026 KEQIESLTE----VHRRELNDVISIWEKKLNQQAEELQEI----HEIQLQ-EKEQEVAEL 1076

Query: 3613 KHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDMK 3672
            K ++        ++ + I  L    + ++T    +   +K    H++    D  K     
Sbjct: 1077 KQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK--A 1134

Query: 3673 RIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLS 3732
             ++   + L     SL     ++E  + L ++ +E K +  +  S +K T+        S
Sbjct: 1135 HLEKLEVDLN---KSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSS 1191

Query: 3733 HSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESK--CFPQ 3790
            H  SN   K+ +DKS   K     L +Q     ++  +      + L N+  SK      
Sbjct: 1192 HEKSN---KSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILS 1248

Query: 3791 KKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVV 3850
            +    +     VK+ + +K  T+   ++  R L   +E    N   ++ T + E   N +
Sbjct: 1249 RISHCQHRTTKVKEALLIKTCTVSELEAQLRQLT--EEQNTLNISFQQATHQLEEKENQI 1306

Query: 3851 QNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIE 3910
            ++           +E     KE   +           QQ+ +   E C   +   LS   
Sbjct: 1307 KSMKA-------DIESLVTEKEALQK-------EGGNQQQAASEKESCITQLKKELSENI 1352

Query: 3911 KAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKI-----QEDKE 3965
             A  + +      E+  EK +    ++ ++   ++  +  +++ EK   I     Q D+E
Sbjct: 1353 NAVTLMK------EELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEE 1406

Query: 3966 VEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNI 4025
                      +SF    KV T+  E+   ++    +S     + S+ +K A  +      
Sbjct: 1407 KCELLDQVQDLSF----KVDTLSKEKISALEQVDDWSN----KFSEWKKKAQSRFTQHQ- 1457

Query: 4026 SNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLT 4085
             N+VK+ L+  L+ + ++  EK   +  +K  + Q        Q KR + +KGE   +  
Sbjct: 1458 -NTVKE-LQIQLELKSKEAYEKDEQINLLKEELDQ--------QNKRFDCLKGE---MED 1504

Query: 4086 NACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA---GEKADGVASKGDIT 4142
            +        S+L+ + + + A  +       L +   QK+ E     E       + DI 
Sbjct: 1505 DKSKMEKKESNLETELKSQTARIME------LEDHITQKTIEIESLNEVLKNYNQQKDIE 1558

Query: 4143 IK--VQKAKDYMQ--QKEDDEVKISAKKDI-----MHPEDKGLKAKKALSQDLPLNTKEP 4193
             K  VQK + + +  +++D+ VK + +K +     ++     L+ KK   + + L+ K  
Sbjct: 1559 HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS- 1617

Query: 4194 GKMDQEAQEQGKEDR-EGEEQGK-EDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGI 4251
                +E + +  EDR E E   K  + +   ++K+    K+      E EEQ K  G   
Sbjct: 1618 ----KEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKK-GTES 1672

Query: 4252 EQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSET 4311
               +++    E+ER +            +IL+ +++  E  Q      ++ PR  K+   
Sbjct: 1673 HLSELNTKLQEREREV------------HILEEKLKSVESSQS---ETLIVPRSAKNVA- 1716

Query: 4312 GKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPL 4371
               A     E DS   VQK           E KIS  +       ++L  K+ L Q +  
Sbjct: 1717 ---AYTEQEEADSQGCVQKTY---------EEKISVLQ-------RNLTEKEKLLQRVGQ 1757

Query: 4372 NPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLF 4431
              +E      E + Q +E     E      E ++ +    +G  QE+ +    K   ++ 
Sbjct: 1758 EKEETVSSHFEMRCQYQERLIKLEHA----EAKQHEDQSMIGHLQEELEEKNKKYSLIVA 1813

Query: 4432 LHLPSESSLTCYELNTRKEGE-EDLQGII--KSATLQLRQQKSFDAGKIAHTKSFGVDSS 4488
             H+  E      +     E   +D+Q  +  K  T Q+ +QK  +               
Sbjct: 1814 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCL---------- 1863

Query: 4489 NDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLT 4548
              V+  + ++ + E    K   +  + Q +G     E L          ++  K++  L 
Sbjct: 1864 --VRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLE--------ENTEEKSKSHLV 1913

Query: 4549 NIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTG 4608
              K  L +++ + ++L+  L        KL K     +++  + R       H +  +  
Sbjct: 1914 QPK-LLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKE-----HQQELEIL 1967

Query: 4609 KLKYTLSYLNDITGDSNRTKYMAQIQKD---KANISEKSVMHPEYIAVKAEKSPLSHILK 4665
            K +Y          D  R + + Q Q+D   K N + K +M  E+    A+K        
Sbjct: 1968 KKEY----------DQEREEKIKQEQEDLELKHNSTLKQLMR-EFNTQLAQKE------- 2009

Query: 4666 TKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPH 4725
             +EL++ I +   KAQE E E++    +      ++  L+  + K+++    + R+   +
Sbjct: 2010 -QELEMTIKETINKAQEVEAELLESHQE-----ETNQLLKKIAEKDDD----LKRTAKRY 2059

Query: 4726 LEIQESLPSRQTAPTK----PTESLVKKEKQLLPQKED 4759
             EI ++     TA  +      E L KK +Q L Q+E+
Sbjct: 2060 EEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2097



 Score = 54.7 bits (130), Expect = 3e-06
 Identities = 318/1662 (19%), Positives = 622/1662 (37%), Gaps = 282/1662 (16%)

Query: 1670 EKKETAIFGSCMPALSTPKTT----RNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRA 1725
            EK E A F     ALST + T    R LK   D +     K    + ++ S+   L+   
Sbjct: 406  EKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS--EEERISLQQELSRVK 463

Query: 1726 GAGPKRRKELSCNLTTKMKELHQ---GKKGVDETYAFLTMTPDINKYSKVETEKDTLREK 1782
                   K+ S     K+++LH+    +K  + T    T   +  +  KV  EK      
Sbjct: 464  QEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYL 523

Query: 1783 RLSSTQVKQDTSPHEDSITSRDI----KETLLQDEEQEERKQEALLKVIPQHLQHFMFRS 1838
            ++S  + +Q++   E+    +       E  L+D +QE       +  +   L+  +  +
Sbjct: 524  KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQEN 583

Query: 1839 -GQGKDLDFHKLENQGSRKILFVTKQDVPQQLQPAEPIQREETK-KCLQTQNGTICTVNS 1896
              Q KDL  H LE + ++    +T             +++ +T+ + L+ Q   + T   
Sbjct: 584  KNQSKDLAVH-LEAEKNKHNKEITVM-----------VEKHKTELESLKHQQDALWT--E 629

Query: 1897 KLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSP 1956
            KL  LK +     E L            KC  E+    K ++  F    QA + E+ +  
Sbjct: 630  KLQVLKQQYQTEMEKLR----------EKCEQEKETLLKDKEIIF----QAHIEEMNEKT 675

Query: 1957 HGGEAQKANLTDMESGSSNAMN-MNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDP 2015
               E      T++ES SS     +  +H+ E++    +L +      Q L     + K+ 
Sbjct: 676  L--EKLDVKQTELESLSSELSEVLKARHKLEEE--LSVLKDQTDKMKQELEAKMDEQKNH 731

Query: 2016 DPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEG 2075
               +  S  K  E         +Q+T++    +   LE +   + ++  H++E    +E 
Sbjct: 732  HQQQVDSIIKEHEVS-------IQRTEKALKDQINQLELL---LKERDKHLKEHQAHVEN 781

Query: 2076 LKTSFPKT-GKSKIGSIPRDTPWDENPRRKWDSSISEKT-AWNQKNLQTVLKPLDFSSLM 2133
            L+    ++ G+ +  S   D        + + S+  E+T A+ ++  Q   K LD  +  
Sbjct: 782  LEADIKRSEGELQQASAKLDV------FQSYQSATHEQTKAYEEQLAQLQQKLLDLET-- 833

Query: 2134 SSEYESRSYTLEFIGKKSMSPK--CVTLKAKQLRILQLFNII-RYSTENHRKKKQHRFKY 2190
                  R    + + +     K  C  L A ++++  L   + + ++E  +K K     Y
Sbjct: 834  -----ERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVY 888

Query: 2191 KMK----------GKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAARCILSNR--T 2238
            + K           KQ        +L   E  K    + +  KL     +  IL+    T
Sbjct: 889  ESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEI-EILTQKLSAKEDSIHILNEEYET 947

Query: 2239 RRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTA-QLSEKEIIFNAKCL 2297
            + +N +  + + K++ +E    +   LLD    +    K   NTA +LS+KE  FNAK L
Sbjct: 948  KFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKL---KKELENTALELSQKEKQFNAKML 1004

Query: 2298 TMKEKKSS-----ISQIHKINRES----TRKHRKKCKSYLKTVSNRKCQENHGHITEEEE 2348
             M +  S+     +S++    +E     T  HR++    +     +        + ++ E
Sbjct: 1005 EMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKK--------LNQQAE 1056

Query: 2349 EVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKI 2408
            E+QE                       I+ IQL E++           ++   + Q   +
Sbjct: 1057 ELQE-----------------------IHEIQLQEKE-----------QEVAELKQKILL 1082

Query: 2409 SGQFTTKHRKKL----ESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEI 2464
             G    +  K++    E  +K         E +     +  S   D + +K     + E+
Sbjct: 1083 FGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLE-KLEV 1141

Query: 2465 DMRISGLSHT----QPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRE-----SGEE 2515
            D+  S   +T    Q  +++ LAE         DKR+ S L    K  D E     S  E
Sbjct: 1142 DLNKSLKENTFLQEQLVELKMLAEE--------DKRKVSELTSKLKTTDEEFQSLKSSHE 1193

Query: 2516 KQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKI--- 2572
            K     E      +       ++ D    K+E +L  +T    +++   +S K   I   
Sbjct: 1194 KSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKT----NELINISSSKTNAILSR 1249

Query: 2573 -----EKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSV-LKENAFC 2626
                  +    KE+L +    + + +  A+L + T++  +     Q   H +  KEN   
Sbjct: 1250 ISHCQHRTTKVKEALLIKTCTVSELE--AQLRQLTEEQNTLNISFQQATHQLEEKENQIK 1307

Query: 2627 NLAAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPD--TAGYAV 2684
            ++ A +   V       E ++++ G          Q +    K+S ++Q     +     
Sbjct: 1308 SMKADIESLV----TEKEALQKEGGN---------QQQAASEKESCITQLKKELSENINA 1354

Query: 2685 VSNNKEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTAD 2744
            V+  KE+ +  K + +     L D   ++  +   + +    S +     E K E    D
Sbjct: 1355 VTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL--LD 1412

Query: 2745 WKTRADPKTFALPKKQQELCVSGTIWS--YPNPYTSISPKIIRHKDKAKTADVESTMHTK 2802
                   K   L K++         WS  +         +  +H++  K   ++  + +K
Sbjct: 1413 QVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSK 1472

Query: 2803 QIKLKAKRITVSQLLEYGTASNKKE--LRGNIQQQKSFQLSKNA---------VHRVLKA 2851
            +   K ++I +  L E     NK+   L+G ++  KS    K +           R+++ 
Sbjct: 1473 EAYEKDEQINL--LKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMEL 1530

Query: 2852 VYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQ 2911
                      I+ L EV    ++ KD    +   +L + L+  Q               +
Sbjct: 1531 EDHITQKTIEIESLNEVLKNYNQQKD----IEHKELVQKLQHFQE------------LGE 1574

Query: 2912 EQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFL-------- 2963
            E+D R KE + + ++ + +Q Y     + +++      +      +EEL+ L        
Sbjct: 1575 EKDNRVKEAEEKILTLE-NQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESES 1633

Query: 2964 ------IAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTSQQKTCQ 3017
                  + ++A++K   I K  +S   E+E   +       KG     +EL+T  Q+  +
Sbjct: 1634 AAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK-------KGTESHLSELNTKLQERER 1686

Query: 3018 EQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDV--------YINRKIS---SH 3066
            E  +L+++  S+ +  S +  ++ P   +N    TE+E+             KIS    +
Sbjct: 1687 EVHILEEKLKSVES--SQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRN 1744

Query: 3067 VLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDP 3126
            +  KE L +    VG + ++ + ++ E++ +    Q+  +  +H      + +S +    
Sbjct: 1745 LTEKEKLLQR---VGQEKEETVSSHFEMRCQY---QERLIKLEHAEAKQHEDQSMIG--- 1795

Query: 3127 LHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKM--DFSKKLRMKHLSNY 3184
             HL++ +    K+   I     E    KE  K +I  K N + +  D  K L+ K L+  
Sbjct: 1796 -HLQEELEEKNKKYSLIVAQHVE----KEGGKNNIQAKQNLENVFDDVQKTLQEKELT-- 1848

Query: 3185 YQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPM 3226
             Q  E  ++ +  C++ Q  +   + E    +    + L  M
Sbjct: 1849 CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM 1890



 Score = 52.8 bits (125), Expect = 1e-05
 Identities = 191/978 (19%), Positives = 379/978 (38%), Gaps = 143/978 (14%)

Query: 2298 TMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPAT 2357
            T++++      + K  +E+ + H+++C   L T      QE      +E E++++     
Sbjct: 283  TLQQRVKRQENLLKRCKETIQSHKEQCT--LLTSEKEALQEQLDERLQELEKIKD----L 336

Query: 2358 FLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCL---TMKEKKPPISQIHKISGQFTT 2414
             +      +  L D+KN I  ++  +  +I   K     T++ K+  I+Q+     Q TT
Sbjct: 337  HMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTT 396

Query: 2415 KHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGLSHT 2474
            +  +  E   K++  A  + E    T   T        + +R+   + E+D +I  +  T
Sbjct: 397  QGEELREQKEKSERAAFEELEKALSTAQKT-------EEARRK--LKAEMDEQIKTIEKT 447

Query: 2475 QPTQIESLAEGIARYS----DPIDKRRTSNLVKGAKLHDRESGEEKQE---HLTEMDPFY 2527
               +  SL + ++R      D + K     + K  KLH++E   ++QE    L   +  +
Sbjct: 448  SEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREF 507

Query: 2528 AENFMA------NTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKES 2581
             E          + YL+  +   + E + L E    K  I    +E   K+   +   E+
Sbjct: 508  QEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIL---TESENKLRDLQQEAET 564

Query: 2582 LKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSP 2641
             +  +  +E S     L ++  +   NK   +++   +  E    N    V   V +H  
Sbjct: 565  YRTRILELESS-----LEKSLQE---NKNQSKDLAVHLEAEKNKHNKEITV--MVEKHKT 614

Query: 2642 ASEEMKRQNGRL-----------KMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKE 2690
              E +K Q   L              +    + +  Q K++ +          +   N++
Sbjct: 615  ELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEK 674

Query: 2691 QKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRAD 2750
              +    ++TE E  L  + +++  A     E +   K    +++ + E K  + K    
Sbjct: 675  TLEKLDVKQTELE-SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQ 733

Query: 2751 PKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDK------AKTADVESTMHTKQI 2804
             +  ++  K+ E+ +  T  +  +    +   +++ +DK      A   ++E+ +   + 
Sbjct: 734  QQVDSI-IKEHEVSIQRTEKALKDQINQLE-LLLKERDKHLKEHQAHVENLEADIKRSEG 791

Query: 2805 KLKAKRITVSQLLEYGTASNKKELRGNIQ----QQKSFQLSKNAVHRVLKAVYDSGYCVS 2860
            +L+     +     Y +A++++      Q    QQK   L    +  + K V +    V 
Sbjct: 792  ELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI-LLTKQVAE----VE 846

Query: 2861 SIKKLTEVKMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQ 2920
            + KK  +V  E D  K +   L Q +LEK   EM++ +   T +     K E   +E+EQ
Sbjct: 847  AQKK--DVCTELDAHKIQVQDLMQ-QLEKQNSEMEQKVKSLTQVYE--SKLEDGNKEQEQ 901

Query: 2921 KHQSISED---ISQYYIG---PLRISSQQINYSSFDAPRIRTDEELEF--------LIAQ 2966
              Q + E    I Q   G    + I +Q+++        +  + E +F         + Q
Sbjct: 902  TKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQ 961

Query: 2967 RAKEKDVGIAKH-----------------SVSIPWEREGSKRLDI-PLNSKGQNIFFTEL 3008
            +AKE    + K                   +S   ++  +K L++   NS G +   + L
Sbjct: 962  KAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRL 1021

Query: 3009 DTSQQKTCQ------EQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRK 3062
            +T+Q++  +       +EL     I    L   A  + E   ++   K  E+E   + +K
Sbjct: 1022 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEK--EQEVAELKQK 1079

Query: 3063 ISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFL 3122
            I      KE + +   ++  +G K   T +E+Q ++  +QK      HV  S+   E+ L
Sbjct: 1080 ILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQL--KQKSA----HV-NSLAQDETKL 1132

Query: 3123 SKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDI---------------TLKSNR 3167
                  L+  +N + KEN  + E   E     E+ K  +               +LKS+ 
Sbjct: 1133 KAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSH 1192

Query: 3168 QKMDFS---KKLRMKHLS 3182
            +K + S   K L  K LS
Sbjct: 1193 EKSNKSLEDKSLEFKKLS 1210



 Score = 41.6 bits (96), Expect = 0.028
 Identities = 73/348 (20%), Positives = 141/348 (40%), Gaps = 33/348 (9%)

Query: 3771 AESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGK-KSLFRHLLHGKEP 3829
            A+ + ++   N I++K   +   +D +  +  K+   L C  L+ K K L   L+  KE 
Sbjct: 1813 AQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKE---LTCQILEQKIKELDSCLVRQKEV 1869

Query: 3830 QRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQ 3889
             R   ++E++T + E  L  +Q            ++   +  E+          S   Q 
Sbjct: 1870 HRV--EMEELTSKYEK-LQALQQ-----------MDGRNKPTELLEENTEEKSKSHLVQP 1915

Query: 3890 ELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQEL 3949
            +L   ME     ++  L+  E+ K    K+  R++K L  +    +  LE+ +    QE 
Sbjct: 1916 KLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQER 1975

Query: 3950 ELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQ---PNL 4006
            E  IK++    QED E++  +     +     +++   E E  M IK   + +Q     L
Sbjct: 1976 EEKIKQE----QEDLELK-HNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAEL 2030

Query: 4007 QESSDTEKTAYEKCIS--DNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQL 4064
             ES   E     K I+  D+      K  E IL   + +   K+R L+     + +  Q 
Sbjct: 2031 LESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQ 2090

Query: 4065 DIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEI 4112
             ++++E       G  +V +      +   + L  D++ ++ E+  +I
Sbjct: 2091 KLEQEEN-----PGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQI 2133



 Score = 37.4 bits (85), Expect = 0.53
 Identities = 102/487 (20%), Positives = 193/487 (39%), Gaps = 85/487 (17%)

Query: 5935 EEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHKARTANLE 5994
            ++K    A T   + +  LEM  +  + Q   ++K  T +   L+E+K +  +A    LE
Sbjct: 360  QDKGMVIAETKRQMHET-LEMKEEE-IAQLRSRIKQMTTQGEELREQKEKSERAAFEELE 417

Query: 5995 KERGRMDTSSSAHPHLLSLKAEESQMKTQVITHRENSRLIMQKQ----KKE----LEASN 6046
            K    + T+         LKAE  +    +    E  R+ +Q++    K+E    ++ S+
Sbjct: 418  K---ALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 474

Query: 6047 AKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIP 6106
             +Q  +LQKL ++           L+ K ++   +L  R+ + +   K    K Q+    
Sbjct: 475  EEQIAKLQKLHEKE----------LARKEQELTKKLQTREREFQEQMKVALEKSQS---- 520

Query: 6107 QMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLERE 6166
            + L I      S  K+ +  + L+ +    K +       L+ S  +      +    R 
Sbjct: 521  EYLKI------SQEKEQQESLALEELELQKKAI-------LTESENKLRDLQQEAETYRT 567

Query: 6167 KRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTN---TVPQDPQPFAVD--KQQMQKLP 6221
            + + L    EKS   ++   +D    ++ E+N  N   TV  +     ++  K Q   L 
Sbjct: 568  RILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALW 627

Query: 6222 NVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDL----RIIEQEEKILKRI-LT 6276
              K +      + ++Y     K R   E +   ++K  ++     I E  EK L+++ + 
Sbjct: 628  TEKLQV-----LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682

Query: 6277 PTECPSMLE------------DPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVK 6324
             TE  S+              + +L   +DQ++ +      K+ +QK       +   +K
Sbjct: 683  QTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNH-HQQQVDSIIK 741

Query: 6325 SSEV------KIVADSTNAEHLLPICEATKAISESQ--VKNMIQD--------KVSSDKL 6368
              EV      K + D  N   LL + E  K + E Q  V+N+  D        + +S KL
Sbjct: 742  EHEVSIQRTEKALKDQINQLELL-LKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL 800

Query: 6369 DNIQAYK 6375
            D  Q+Y+
Sbjct: 801  DVFQSYQ 807



 Score = 35.8 bits (81), Expect = 1.6
 Identities = 67/301 (22%), Positives = 122/301 (40%), Gaps = 46/301 (15%)

Query: 5823 QNIEEQD-IVMKKQVIRRCEHGHKTRTNTILSKFPLQSGKQKTPS--ETDVDKKTTAHLS 5879
            Q I+E D  +++++ + R E    T     L       G+ K     E + ++K+ +HL 
Sbjct: 1854 QKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLV 1913

Query: 5880 ----LQMLPGIHMDMTEIDPAKGGRKQALLISE--QEEGVLEFLPKSLFPPWTFQFQSGD 5933
                L  +   H D+ E   A   R++  L  E  + +  L  L K        Q +   
Sbjct: 1914 QPKLLSNMEAQHNDL-EFKLAGAEREKQKLGKEIVRLQKDLRMLRKE------HQQELEI 1966

Query: 5934 LEEKHQTDANTNINLEQKKLEMDNDSTVN-----------QKEGKL----KIGTNRALHL 5978
            L++++  +    I  EQ+ LE+ ++ST+            QKE +L    K   N+A  +
Sbjct: 1967 LKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEV 2026

Query: 5979 QEEKTEMHKARTANLEKERGRMD----TSSSAHPHLLSLKAEESQMKTQVITHRENSRLI 6034
            + E  E H+  T  L K+    D     ++  +  +L  + EE   K + +  +      
Sbjct: 2027 EAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQK 2086

Query: 6035 MQKQKKELEASNAKQSIQLQ----KLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRE 6090
              +QK E E +    ++ +     +L Q+  L S         K K+Q+ R  I +L+  
Sbjct: 2087 KYQQKLEQEENPGNDNVTIMELQTQLAQKTTLIS-------DSKLKEQEFREQIHNLEDR 2139

Query: 6091 L 6091
            L
Sbjct: 2140 L 2140


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 58.2 bits (139), Expect = 3e-07
 Identities = 186/978 (19%), Positives = 386/978 (39%), Gaps = 152/978 (15%)

Query: 3701 LDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQ 3760
            L ++  E     G+  +  K T   T+L  LS        +    +S     CL  +++ 
Sbjct: 1953 LSVVTSERNQLRGELDTMSKKT---TALDQLSEKMKEKTQELESHQSE----CLHCIQVA 2005

Query: 3761 ASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLF 3820
             +    +    ++++ D +S +++ K   Q+K +  E     KD   L  +T    ++  
Sbjct: 2006 EAEVKEKTELLQTLSSD-VSELLKDKTHLQEKLQSLE-----KDSQALS-LTKCELENQI 2058

Query: 3821 RHLLHGKE--PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPH--LEWNPRIKEVYM- 3875
              L   KE   + S     ++++ D   LNV    L A+++      L  +   +EV+  
Sbjct: 2059 AQLNKEKELLVKESESLQARLSESDYEKLNV-SKALEAALVEKGEFALRLSSTQEEVHQL 2117

Query: 3876 -RGI----TRFCLSSSTQQELSDTMEKCEQPID---DSLSSIEKAKHMPQKDKDRV---- 3923
             RGI     R       Q  +++ +++ E+  D   D + ++E+   M +++++ V    
Sbjct: 2118 RRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDA 2177

Query: 3924 EKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSK 3983
            E +  ++   K    E+ +     EL+L +  +  K    K+++      + +  L  S 
Sbjct: 2178 ENSKAEVETLKTQIEEMARSLKVFELDL-VTLRSEKENLTKQIQEKQGQLSELDKLLSSF 2236

Query: 3984 VGTIEGEEA--MRIKMRSSFSQPNLQES-SDTEKTAYEKCISDNISNSVKKALESILQKE 4040
               +E +E   ++IK  S  +   LQ    +  +     C    I  + +++L+  +++E
Sbjct: 2237 KSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEE 2296

Query: 4041 Q--RQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQ 4098
               R  +EK+RA  +        +   +KE E   + +KG    L      +  +  H  
Sbjct: 2297 HQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAA 2356

Query: 4099 LDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGV---ASKGDITIKVQKAKD----- 4150
            L+    K E  T        ++     S  G + D V   + K ++T ++QK ++     
Sbjct: 2357 LEAENSKGEVET-----LKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISEL 2411

Query: 4151 ---------YMQQKEDDEVKISAKKD------------------IMHPEDKGLKAKKA-L 4182
                      +Q+KE ++V++  K                     +H + +  KAK+  L
Sbjct: 2412 EIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2471

Query: 4183 SQDLPLNTKEPGKMDQEAQEQG------KEDREGEEQGKEDRRGAGQEKVDREDKEQGKM 4236
            S  +     E  ++ Q   E        +    G  Q  ED    G++K++++D+E  ++
Sbjct: 2472 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVED----GKQKLEKKDEEISRL 2527

Query: 4237 DHEVEEQQKADGVGIEQGKMDGDKN--------------EQERVLFLYLPSNSSL--THY 4280
             +++++Q++   +  +  +++G+                E E+ + +    N+SL  T  
Sbjct: 2528 KNQIQDQEQ---LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLE 2584

Query: 4281 ILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEE 4340
            +L +  +  E++  + +   +    + +  T K+      + +     QK  +  ++   
Sbjct: 2585 VLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETE---LQREMHEMAQKTAELQEELSG 2641

Query: 4341 DEVKISAEKDLMHPEDKDLKG--KKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGN 4398
            ++ +++ E  L+  E K  K   K+   +N  L          + +++GK   E  E   
Sbjct: 2642 EKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQL 2701

Query: 4399 RDGETEEQQQADGVGTE-------QEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEG 4451
            R  E E++ QA  + T        Q  R+   SK+E +         S    E++  K  
Sbjct: 2702 RLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECL---------SSQKLEIDLLKSS 2752

Query: 4452 EEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGK---T 4508
            +E+L   +K+ T  L + K                  +++K V + K + E  +GK    
Sbjct: 2753 KEELNNSLKATTQILEELKK--------------TKMDNLKYVNQLKKENERAQGKMKLL 2798

Query: 4509 VSVDYIMQPEGTIFEAE--QLSLPHTLNIPGS-SGSKTREVLTNIKEKLRHVQERKSELD 4565
            +     ++ E  I + E  QL         G+   +K  E+ T IKE    ++E+  E D
Sbjct: 2799 IKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEAD 2858

Query: 4566 VFL---TIPSLSHCKLDK 4580
             +L       +SH KL+K
Sbjct: 2859 EYLDKYCSLLISHEKLEK 2876



 Score = 45.4 bits (106), Expect = 0.002
 Identities = 152/765 (19%), Positives = 285/765 (37%), Gaps = 156/765 (20%)

Query: 5975 ALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKTQVITHRENSRLI 6034
            AL  Q++K E  K    NL++E  R+     +        + E Q+K   +  +E     
Sbjct: 47   ALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNS 106

Query: 6035 MQKQ-----------KKELEASN-AKQSIQL--------QKLFQRNVLDSFYSYVPLSPK 6074
             +KQ           K ELE S  A QS  +        QK+F   +  S Y Y     +
Sbjct: 107  GKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQY-YSGSKYE 165

Query: 6075 RKDQKGRLTIRDLKR-ELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIA 6133
               +K    + + KR E   K L  K  +  +PQ           N + +       ++ 
Sbjct: 166  DLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQ--------ATMNHRDIARHQASSSVF 217

Query: 6134 SWSKDVSGIFIRSLSISIMRSPHTDPKTNLERE-KRICLPKFQEKSPNTSEMSKRDTLTI 6192
            SW ++ +   + S S           +T + R+         QE +P+      R TL I
Sbjct: 218  SWQQEKTPSHLSSNS----------QRTPIRRDFSASYFSGEQEVTPS------RSTLQI 261

Query: 6193 VKGEQNFTNTVPQDPQPFAVD--KQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEH 6250
             K + N ++       P  +D  K Q Q+L N  +E  LR + ++K +K Q  +      
Sbjct: 262  GKRDAN-SSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKF----Q 316

Query: 6251 DVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKV--- 6307
            ++   ++K  + +IE+E+ + K       C   L   +   Q DQ+   +    QK+   
Sbjct: 317  ELQLQLEKAKVELIEKEKVLNK-------CRDELV--RTTAQYDQASTKYTALEQKLKKL 367

Query: 6308 ------QQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEA---------TKAISE 6352
                  Q+Q A      +  ++K  E +   + +  +      +          T+ + +
Sbjct: 368  TEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQ 427

Query: 6353 SQ-VKNMIQDKVSSDKLDNIQAYKPDDLKS--PPFPEGPDTISTAIYPKTQHKSLLEQFT 6409
            ++ + N++Q ++  DKL +++    ++L+               +   + + +  +E+  
Sbjct: 428  AKNMHNVLQAEL--DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMK 485

Query: 6410 PKEKNKLTSHLESKA-----LEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSR-- 6462
             KE N L SH E KA     LE +L  I +   +S            S++   R      
Sbjct: 486  -KENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKI 544

Query: 6463 HKTMNFMSLE---------------GTDTIEPNSKHKHQKDSPLA--------------- 6492
            ++  N ++LE                 D ++    H  Q +  L+               
Sbjct: 545  NQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALEL 604

Query: 6493 --------SNMKTLIVDVSSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQNHSVK 6544
                       KTL     S++E+ +T+++S  + EN  S +      L    +++H   
Sbjct: 605  KKKEYEELKEEKTLFSCWKSENEKLLTQMES--EKENLQSKINHLETCLKTQQIKSHEYN 662

Query: 6545 EKGKLL-------------MH--FSVKTLEIQMKAFPRIVRESYAMTSAHERKKPLSN-C 6588
            E+ + L             +H     K++E++ +    +  +  A  S  + +K + N C
Sbjct: 663  ERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMC 722

Query: 6589 IHPG-FTGPKR--QNRILLLSEE---KSLHQIDLDLQYKYLRFLL 6627
            +     TG     ++++ LLS E   K     DL  +Y+ LR LL
Sbjct: 723  LKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLL 767



 Score = 40.8 bits (94), Expect = 0.048
 Identities = 129/679 (18%), Positives = 258/679 (37%), Gaps = 95/679 (13%)

Query: 3891 LSDTMEKCEQPIDDSLSSIEKAKHMPQKDKD---RVEKALEKIMHSKRIALEVKQPSI-F 3946
            L   ++K +Q +++  +     K   Q+  +    +EK  +KI H     L+VK+  + F
Sbjct: 44   LEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHE----LQVKESQVNF 99

Query: 3947 QELELN--------IKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMR 3998
            QE +LN        ++++  + + + E    +   A +S  P +    I        +  
Sbjct: 100  QEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYY 159

Query: 3999 SSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQ---------KEQRQKMEKIR 4049
            S     +L+E  + E    ++  ++  +   KKA +++ Q         + Q        
Sbjct: 160  SGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSW 219

Query: 4050 ALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI------------PSPSHL 4097
              +K  S +S   Q     ++    +  GE  V  + +   I             S  HL
Sbjct: 220  QQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHL 279

Query: 4098 QLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKE- 4156
                + +  E   +I    L    H+K     E    V    ++ ++++KAK  + +KE 
Sbjct: 280  LDQLKAQNQELRNKINELELRLQGHEK-----EMKGQVNKFQELQLQLEKAKVELIEKEK 334

Query: 4157 ------DDEVKISAKKDIMHPEDKGLKAK-KALSQDLPLNTKEPGKMDQEAQEQGKED-R 4208
                  D+ V+ +A+ D    +   L+ K K L++DL              Q Q  E  R
Sbjct: 335  VLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDL------------SCQRQNAESAR 382

Query: 4209 EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLF 4268
               EQ  +++    QE++ R+ +    +D E  + +      ++Q K          VL 
Sbjct: 383  CSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAK------NMHNVLQ 436

Query: 4269 LYLPSNSSLTHYILDTRIEGEED----QQGIIRPGILQPRHQKSSETGKKANGVPSEGDS 4324
              L   +S+   + +   E ++     +Q      I +   ++S E  KK N +      
Sbjct: 437  AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496

Query: 4325 A---------SEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQN-LPLNPK 4374
                      +E++  K  + Q +    ++ A+        +DL+ K    +N L L   
Sbjct: 497  QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKL 556

Query: 4375 EPGKRDGEGQEQGKED------GEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQET 4428
            +    D E Q    +D         E+  ++  +TE++ +A     E +K++  + K+E 
Sbjct: 557  KLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEK 616

Query: 4429 VLFLHLPSESSLTCYELNTRKEGEEDLQGIIK--SATLQLRQQKSFDAGKIAHTKSFGVD 4486
             LF    SE+     ++ + K   E+LQ  I      L+ +Q KS +  +   T     +
Sbjct: 617  TLFSCWKSENEKLLTQMESEK---ENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRE 673

Query: 4487 S-SNDVKTVQEYKPQKEVD 4504
            + S +++ +      K V+
Sbjct: 674  NLSVEIRNLHNVLDSKSVE 692



 Score = 38.9 bits (89), Expect = 0.18
 Identities = 161/853 (18%), Positives = 329/853 (38%), Gaps = 144/853 (16%)

Query: 1578 QKDNE-----LVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFP------FEK 1626
            +KDNE     +V  +EEL+   S   Q++ +     T+ K T+   LDQ         ++
Sbjct: 1936 EKDNENKQKVIVCLEEELSVVTSERNQLRGEL---DTMSKKTTA--LDQLSEKMKEKTQE 1990

Query: 1627 VESH----VRFSPLKSGEAKVDEIIFYAREGGISS---DSSHQKEQAGGTEKKETAIFGS 1679
            +ESH    +    +   E K    +       +S    D +H +E+    EK   A+   
Sbjct: 1991 LESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQAL--- 2047

Query: 1680 CMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISY-MLNIRAG--AGPKRRKELS 1736
               +L+  +    + Q +  K L+  +   ++A+     Y  LN+     A    + E +
Sbjct: 2048 ---SLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFA 2104

Query: 1737 CNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPH 1796
              L++  +E+HQ ++G+++    + +  D  K   +  EK   RE+   S + K +    
Sbjct: 2105 LRLSSTQEEVHQLRRGIEKLR--VRIEADEKKQLHI-AEKLKERERENDSLKDKVENLER 2161

Query: 1797 EDSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRK 1856
            E  + S + +E ++ D E  + + E L   I +     M RS +  +LD   L ++    
Sbjct: 2162 ELQM-SEENQELVILDAENSKAEVETLKTQIEE-----MARSLKVFELDLVTLRSE---- 2211

Query: 1857 ILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAI 1916
                 K+++ +Q+Q  +  Q  E  K L +    +       + +K E     E+L   +
Sbjct: 2212 -----KENLTKQIQEKQG-QLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQL 2265

Query: 1917 KRGVPTDRKCMGEQHNSGKGEKA-----EFNKDLQATVLELQKSPHGGE-AQKANLTDME 1970
            K          G+Q      E++     E    L+ ++ +L+      E  Q   L  ++
Sbjct: 2266 KELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLK 2325

Query: 1971 SGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMK-DPDPCKSGSEPKSPEG 2029
                +A  +  + E  ++ ++   T       +H        K + +  K+  E  +   
Sbjct: 2326 ESEHHADLLKGRVENLERELEIARTN-----QEHAALEAENSKGEVETLKAKIEGMTQSL 2380

Query: 2030 RSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIG 2089
            R   L  +  ++++E    E   E             QE I  +E + +SF    + K  
Sbjct: 2381 RGLELDVVTIRSEKENLTNELQKE-------------QERISELEIINSSFENILQEK-- 2425

Query: 2090 SIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLD--FSSLMSSEYESRSYTLEFI 2147
                          +    + EK++   + LQT LK L+   ++L + +   ++      
Sbjct: 2426 -------------EQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKA------ 2466

Query: 2148 GKKSMSPKCVTLKAKQLRILQLFN------IIRYSTENHRKKKQHRFKYKMKGKQWYTSI 2201
             ++++S +   L+ ++ ++LQ  +      I+  S+ N   ++    K K++ K    S 
Sbjct: 2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISR 2526

Query: 2202 GEALLSATEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLD-GHITEEKEEVQENVAA 2260
             +  +   E   S  S+   +  L+            + QNL+  ++T E E+  + + +
Sbjct: 2527 LKNQIQDQEQLVSKLSQVEGEHQLW------------KEQNLELRNLTVELEQKIQVLQS 2574

Query: 2261 IFLGLLDFFMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKH 2320
                L D    + S  KN  N  +            LT  +K S + +++K+  + T   
Sbjct: 2575 KNASLQDTLEVLQSSYKNLENELE------------LTKMDKMSFVEKVNKMTAKETELQ 2622

Query: 2321 RKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQ 2380
            R+  +   KT              +EE   ++N  A   G L   +  +  SK+Q+  + 
Sbjct: 2623 REMHEMAQKTAE-----------LQEELSGEKNRLA---GELQLLLEEIKSSKDQLKELT 2668

Query: 2381 LSERKIILNPKCL 2393
            L   ++  +  C+
Sbjct: 2669 LENSELKKSLDCM 2681



 Score = 38.1 bits (87), Expect = 0.31
 Identities = 112/552 (20%), Positives = 217/552 (39%), Gaps = 94/552 (17%)

Query: 5918 PKSLF--PPWTFQFQSG----DLEEKHQTDANTNINLE--------QKKLEMDNDSTVNQ 5963
            P+ +F  P    Q+ SG    DL+EK+  +      LE        +K  +    +T+N 
Sbjct: 145  PQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNH 204

Query: 5964 KEGKLKIGTNRALHLQEEKTEMHKARTANLEKER-----------------------GRM 6000
            ++      ++     Q+EKT  H +  +     R                       G+ 
Sbjct: 205  RDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIGKR 264

Query: 6001 DTSS-----SAHPHLL-SLKAEESQMKTQVITHRENSRLIMQKQKKELEAS-NAKQSIQL 6053
            D +S     S+ PHLL  LKA+  +++ ++        L +Q  +KE++   N  Q +QL
Sbjct: 265  DANSSFFDNSSSPHLLDQLKAQNQELRNKI----NELELRLQGHEKEMKGQVNKFQELQL 320

Query: 6054 QKLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITG 6113
            Q   ++  ++       L+ K +D+  R T +    + STKY  ++ +   + + L+   
Sbjct: 321  Q--LEKAKVELIEKEKVLN-KCRDELVRTTAQ--YDQASTKYTALEQKLKKLTEDLSCQR 375

Query: 6114 RGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPK 6173
            +   S R  LE  +K K    + +++S            RS  T  +  ++ + R+    
Sbjct: 376  QNAESARCSLEQKIKEKE-KEFQEELS---------RQQRSFQTLDQECIQMKARLTQEL 425

Query: 6174 FQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEM 6233
             Q K+ +    ++ D LT VK  Q   N + +  Q     +Q  Q     ++E     E 
Sbjct: 426  QQAKNMHNVLQAELDKLTSVK--QQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEE 483

Query: 6234 NKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDPKLPKQR 6293
             KK      +  ++  H      K  ++  +E E K +K+ L  ++  +  E+ K  K  
Sbjct: 484  MKK------ENNLLKSHSEQ---KAREVCHLEAELKNIKQCLNQSQ--NFAEEMK-AKNT 531

Query: 6294 DQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKI-VADSTNAEHLLPICEATKAISE 6352
             Q   + D+  +K+ QQ+           +   ++K+ VAD          C        
Sbjct: 532  SQETMLRDL-QEKINQQE---------NSLTLEKLKLAVADLEKQRD----CSQDLLKKR 577

Query: 6353 SQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQFTPKE 6412
                  + DK+S  + ++       +LK   + E  +  +     K++++ LL Q   ++
Sbjct: 578  EHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEK 637

Query: 6413 KN--KLTSHLES 6422
            +N     +HLE+
Sbjct: 638  ENLQSKINHLET 649



 Score = 37.4 bits (85), Expect = 0.53
 Identities = 81/403 (20%), Positives = 162/403 (40%), Gaps = 62/403 (15%)

Query: 5892 EIDPAKGGRKQALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQK 5951
            E++ A+  ++ A L +E  +G +E L K+     T   +  +L+         N+  E +
Sbjct: 2344 ELEIARTNQEHAALEAENSKGEVETL-KAKIEGMTQSLRGLELDVVTIRSEKENLTNELQ 2402

Query: 5952 K-------LEMDNDSTVN------QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERG 5998
            K       LE+ N S  N      Q++ ++K  ++ A+ + + + +    R A L  ++ 
Sbjct: 2403 KEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQE 2462

Query: 5999 RMDTSS-SAHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKEL--EASNAKQSIQLQK 6055
                   +    +  L+ E++Q+  Q +   +N+ +++Q     L  E  + KQ ++ + 
Sbjct: 2463 ACKAKEQNLSSQVECLELEKAQL-LQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKD 2521

Query: 6056 LFQRNVLDSFYSYVPLSPKRKDQKGR--------LTIRDLKRELSTKYLTMKIQNHPIPQ 6107
                 + +       L  K    +G         L +R+L  EL  K   ++ +N  +  
Sbjct: 2522 EEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQD 2581

Query: 6108 MLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREK 6167
             L +      S+ K LE +++L  +   S      F+  ++        T  +T L+RE 
Sbjct: 2582 TLEVL----QSSYKNLENELELTKMDKMS------FVEKVN------KMTAKETELQRE- 2624

Query: 6168 RICLPKFQEKSPNTSEMSKRDTLTIVKGEQN-FTNTVPQDPQPFAVDKQQMQKLPNVKSE 6226
                    E +  T+E+ +      + GE+N     +    +     K Q+++L    SE
Sbjct: 2625 ------MHEMAQKTAELQEE-----LSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSE 2673

Query: 6227 ANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEK 6269
                    KK L    K+++  E  V   I +  LR+ E E+K
Sbjct: 2674 L-------KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKK 2709



 Score = 36.2 bits (82), Expect = 1.2
 Identities = 40/161 (24%), Positives = 74/161 (45%), Gaps = 16/161 (9%)

Query: 2867 EVKMEKDKPKDRTCILPQ--PKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQS 2924
            +++ E D    +T  L Q   K+++  +E++   S C     +    E +++EK +  Q+
Sbjct: 1962 QLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVA---EAEVKEKTELLQT 2018

Query: 2925 ISEDISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSI-- 2982
            +S D+S+       +  +  +          T  ELE  IAQ  KEK++ + K S S+  
Sbjct: 2019 LSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKEL-LVKESESLQA 2077

Query: 2983 -----PWER-EGSKRLDIPLNSKGQNIFFTELDTSQQKTCQ 3017
                  +E+   SK L+  L  KG+  F   L ++Q++  Q
Sbjct: 2078 RLSESDYEKLNVSKALEAALVEKGE--FALRLSSTQEEVHQ 2116



 Score = 35.4 bits (80), Expect = 2.0
 Identities = 204/986 (20%), Positives = 373/986 (37%), Gaps = 169/986 (17%)

Query: 3770 SAESINRDSLSNVIESKCFPQKKKEDRENIVDVK---DVMGLKCITLKGKKSLFRHLLHG 3826
            S +  N +S    +E K   +K+KE +E +   +     +  +CI +K +  L + L   
Sbjct: 372  SCQRQNAESARCSLEQK-IKEKEKEFQEELSRQQRSFQTLDQECIQMKAR--LTQELQQA 428

Query: 3827 KEP----QRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFC 3882
            K      Q    KL  + Q+ E+NL   + KLC                    R    F 
Sbjct: 429  KNMHNVLQAELDKLTSVKQQLENNLEEFKQKLC--------------------RAEQAFQ 468

Query: 3883 LSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKD--RVEKALEKIM----HSKRI 3936
             S   + EL  +ME+ ++  ++ L S     H  QK ++   +E  L+ I      S+  
Sbjct: 469  ASQIKENELRRSMEEMKKE-NNLLKS-----HSEQKAREVCHLEAELKNIKQCLNQSQNF 522

Query: 3937 ALEVKQPSIFQELEL-NIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRI 3995
            A E+K  +  QE  L +++EK    Q++  + +                      E +++
Sbjct: 523  AEEMKAKNTSQETMLRDLQEKIN--QQENSLTL----------------------EKLKL 558

Query: 3996 KMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVK--KALESILQKEQRQKMEKIRALKK 4053
             +     Q +  +    ++  + + ++D +S + K  KAL S L+ ++++  E    LK+
Sbjct: 559  AVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEE----LKE 614

Query: 4054 MKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQ--LDTRREKAEYVTE 4111
             K+  S        E EK +  ++ E   L +         +HL+  L T++ K+    E
Sbjct: 615  EKTLFS----CWKSENEKLLTQMESEKENLQSKI-------NHLETCLKTQQIKSHEYNE 663

Query: 4112 ITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHP 4171
              R    E+  +  S        V     + ++ QK   YM+ ++  + + S +K     
Sbjct: 664  RVRTL--EMDRENLSVEIRNLHNVLDSKSVEVETQKLA-YMELQQ--KAEFSDQKHQKEI 718

Query: 4172 EDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGK--EDREGEEQGKED-RRGAGQEKVDR 4228
            E+  LK  +   Q   L  K    +  E  ++ +  +D   E +   D  +      V  
Sbjct: 719  ENMCLKTSQLTGQVEDLEHKLQ-LLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTN 777

Query: 4229 EDKEQGKMDHEVEEQQKADGVGI--EQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRI 4286
            ED ++  +  + +         I  EQG M  +++E  R+     P NS+    IL  R+
Sbjct: 778  EDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSEC-RLEADQSPKNSA----ILQNRV 832

Query: 4287 EGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKIS 4346
            +  E                 S E+ K+ N         S++QK     Q +E  ++K  
Sbjct: 833  DSLE----------------FSLESQKQMN---------SDLQK-----QCEELVQIKGE 862

Query: 4347 AEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQE--QGKEDGEGEEQGNRDG-ET 4403
             E++LM  E          SQ +    ++         E     E+ E E Q   D  ET
Sbjct: 863  IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVET 922

Query: 4404 EEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQ--GIIKS 4461
            E+ +  +   +     D  K  Q     L L  +   +   LN ++E EE  Q  G +K 
Sbjct: 923  EQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLN-KREIEELTQENGTLKE 981

Query: 4462 ATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTI 4521
                L Q+K      I  ++SF        K++ E       D+ K   +  + + E T 
Sbjct: 982  INASLNQEK---MNLIQKSESFANYIDEREKSISELS-----DQYKQEKLILLQRCEETG 1033

Query: 4522 FEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKR 4581
               E LS  +      ++  K  ++   + E     + RK+EL+      +  H +   +
Sbjct: 1034 NAYEDLSQKYK-----AAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTK 1088

Query: 4582 TAGKKEE-----------QGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYM 4630
             A  +E            Q   RS +  + +   S+ G LK  +  L +    +   K +
Sbjct: 1089 LAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKE--EQNKMQKEV 1146

Query: 4631 AQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQ-EGEVEIVV 4689
              + ++   + +  VM  ++     E  P+ + +K +E + N  Q   K Q + EV+ + 
Sbjct: 1147 NDLLQENEQLMK--VMKTKHECQNLESEPIRNSVKERESERN--QCNFKPQMDLEVKEIS 1202

Query: 4690 LLSKTCPFVTSSAFLELDSIKEEEGE 4715
            L S     V   A L    +K +E E
Sbjct: 1203 LDSYNAQLVQLEAMLRNKELKLQESE 1228


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 668

 Score = 57.8 bits (138), Expect = 4e-07
 Identities = 75/422 (17%), Positives = 189/422 (44%), Gaps = 45/422 (10%)

Query: 4018 EKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIK 4077
            E+   +  + S++    +I  +E ++K  K++   ++  S    IQL++KE ++++E  K
Sbjct: 196  EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 255

Query: 4078 GEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVAS 4137
                 LL           HL  + +   A+   ++    L    +Q+  E   + +    
Sbjct: 256  -----LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 310

Query: 4138 KGDITIKVQKAKDYMQQKE--DDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGK 4195
            + +  I+ Q+ K   Q+++  + E K+  ++++M  +++ ++ ++ +  +     ++  +
Sbjct: 311  EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE---KEEKMRR 367

Query: 4196 MDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGK 4255
            +++   E+ ++ RE EE+  E      QEK+ RE +E+ + + ++ EQ+K      +  +
Sbjct: 368  LEEMMWEKEEKIRELEEKMHE------QEKI-REQEEKRQEEEKIREQEKRQEQEAKMWR 420

Query: 4256 MDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKA 4315
             +    EQE  +            +  + +I  +E     IR    + + Q+  E  ++ 
Sbjct: 421  QEEKIREQEEKI-----REQEKKMWRQEEKIHEQEK----IRE---EEKRQEQEEMWRQE 468

Query: 4316 NGVPSEGDSASEVQKAKDYMQQKE---EDEVKISAEKDLMHPEDKDLK---------GKK 4363
              +  +     E+ + K+ M ++E   + E K+  +++ MH +++ ++          +K
Sbjct: 469  EKIREQ----EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524

Query: 4364 ALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHK 4423
               Q   +  +E   R+ E   Q +E+  GE++     + + ++Q + +  ++EK    K
Sbjct: 525  IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584

Query: 4424 SK 4425
             K
Sbjct: 585  EK 586



 Score = 53.5 bits (127), Expect = 7e-06
 Identities = 92/463 (19%), Positives = 198/463 (42%), Gaps = 71/463 (15%)

Query: 3790 QKKKEDR--ENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNL 3847
            QKKK DR  E +   +D + L+         L+R+ +  +E +  N KL++  Q  ES  
Sbjct: 187  QKKKADRYIEELTKERDALSLE---------LYRNTITDEELKEKNAKLQEKLQLVESEK 237

Query: 3848 NVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLS 3907
            + +Q       L+   L+      ++ +        +    +EL     K +  ++++  
Sbjct: 238  SEIQ-------LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN-- 288

Query: 3908 SIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVE 3967
              E    + Q+ ++++ +  EKI   +    E  Q    +E E  I+E+  K++  +E+ 
Sbjct: 289  --ELWNRLNQQQEEKMWRQEEKIQEWEEKIQE--QEEKIREQEEKIREQEEKMRRQEEM- 343

Query: 3968 IWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISN 4027
            +W K                  EE MR +    + +   ++    E+  +EK   + I  
Sbjct: 344  MWEK------------------EEKMRRQEEMMWEKE--EKMRRLEEMMWEK--EEKIRE 381

Query: 4028 SVKKALESIL---QKEQRQKMEKIRALKKMKSSISQGIQLD--IKEQEKRIEHIKGEPSV 4082
              +K  E      Q+E+RQ+ EKIR  +K +   ++  + +  I+EQE++I     E   
Sbjct: 382  LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR----EQEK 437

Query: 4083 LLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDIT 4142
             +      I     ++ + +R++ E        +  E   ++  E   + + +  +  I 
Sbjct: 438  KMWRQEEKIHEQEKIREEEKRQEQE------EMWRQEEKIREQEEIWRQKEKMHEQEKIR 491

Query: 4143 IKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQE 4202
             + +K     ++  D E KI  +++ M  ++     +K   Q+  +  +E    +QE   
Sbjct: 492  KQEEKVWRQEEKMHDQEEKIREQEEKMWRQE-----EKIREQEEKIREQEEKIREQEEMM 546

Query: 4203 QGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQK 4245
            Q +E++ GE++ K       QEK+ R++++  + + ++ EQ++
Sbjct: 547  QEQEEKMGEQEEKMQE----QEKMRRQEEKIREQEEKIREQKE 585



 Score = 46.2 bits (108), Expect = 0.001
 Identities = 76/494 (15%), Positives = 211/494 (42%), Gaps = 75/494 (15%)

Query: 3948 ELELNIKEKGGKIQEDK----------EVEIWSKPFASISFLPYSKVGTIEGEEAMRIKM 3997
            E++LN+KE   K++  K          E +   K   S+S    ++V      E   +  
Sbjct: 239  EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV------EENELWN 292

Query: 3998 RSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQR-QKMEKIRALKKMKS 4056
            R +  Q       + +   +E+ I +     +++  E I ++E++ ++ E++   K+ K 
Sbjct: 293  RLNQQQEEKMWRQEEKIQEWEEKIQEQ-EEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351

Query: 4057 SISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYY 4116
               + +  + +E+ +R+E +  E    +             +L+ +  + E + E     
Sbjct: 352  RRQEEMMWEKEEKMRRLEEMMWEKEEKIR------------ELEEKMHEQEKIRE----- 394

Query: 4117 LPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGL 4176
              E   Q+  +  E+      +  +  + +K ++  ++  + E K+  +++ +H ++K  
Sbjct: 395  -QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453

Query: 4177 KAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKM 4236
            + +K   Q+      E  + +++ +EQ +  R+ E+  ++++    +EKV R++++    
Sbjct: 454  EEEKRQEQE------EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507

Query: 4237 DHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGII 4296
            + ++ EQ++      +  + +    EQE  +                     E++++   
Sbjct: 508  EEKIREQEE------KMWRQEEKIREQEEKI--------------------REQEEKIRE 541

Query: 4297 RPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPED 4356
            +  ++Q + +K  E  +K   +  +     + +K ++  ++  E + KI  +++ +  ++
Sbjct: 542  QEEMMQEQEEKMGEQEEK---MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598

Query: 4357 KDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQ 4416
            + ++ ++ + Q       E  ++  E +E+ +E    +E+  R  E +  +Q   +  ++
Sbjct: 599  EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE----QEEKMRRQEEKMWEQEVRLRQQE 654

Query: 4417 EKRDGHKSKQETVL 4430
            EK   H+   E  +
Sbjct: 655  EKMQEHQEHLEAAI 668



 Score = 33.5 bits (75), Expect = 7.7
 Identities = 86/471 (18%), Positives = 183/471 (38%), Gaps = 69/471 (14%)

Query: 2574 KNKNGKESLKVGLARMEKSD---NCAELSEATDDAI------SNKYDKQNIGHSVLKENA 2624
            K KN K   K+ L   EKS+   N  EL    + A         + +  ++G  +   +A
Sbjct: 220  KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279

Query: 2625 FCNLAAIVPDSVGRHSPASEE-MKRQNGRLK-MADRSSPQGRPLQAKQSAVSQSPDTAGY 2682
                     +   R +   EE M RQ  +++   ++   Q   ++ ++  + +  +    
Sbjct: 280  KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM-- 337

Query: 2683 AVVSNNKEQKQNFKAQKTEAEVDLI-DQEAKINVAEEFNPESVFFSKIHPLQ--IENKKE 2739
                  +E+    K +K   + +++ ++E K+   EE   E     KI  L+  +  +++
Sbjct: 338  ----RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE--EKIRELEEKMHEQEK 391

Query: 2740 FKTADWKTRADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTM 2799
             +  + K + + K     K+Q++      +W           KI R ++K      E   
Sbjct: 392  IREQEEKRQEEEKIREQEKRQEQ---EAKMWRQEEKIREQEEKI-REQEKKMWRQEEKIH 447

Query: 2800 HTKQIKLKAKRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCV 2859
              ++I+ + KR    ++               I++Q+     K  +H   K         
Sbjct: 448  EQEKIREEEKRQEQEEMWRQ---------EEKIREQEEIWRQKEKMHEQEK--------- 489

Query: 2860 SSIKKLTE-VKMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREK 2918
              I+K  E V  +++K  D+     + K+ +  ++M R      +    +R+QE+ IRE+
Sbjct: 490  --IRKQEEKVWRQEEKMHDQ-----EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542

Query: 2919 EQKHQSISEDISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKH 2978
            E+  Q   E      +G      Q+         +IR  EE       + +E+   I + 
Sbjct: 543  EEMMQEQEEK-----MGEQEEKMQEQEKMRRQEEKIREQEE-------KIREQKEKIREQ 590

Query: 2979 SVSIPWEREGSKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISM 3029
               I WE+E   R    +  + +   + +    ++K C+++E +++++  M
Sbjct: 591  EEKI-WEQEEKIREQEEMMQEQEEKMWEQ----EEKMCEQEEKMQEQEEKM 636


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
          Length = 570

 Score = 57.0 bits (136), Expect = 7e-07
 Identities = 90/460 (19%), Positives = 204/460 (44%), Gaps = 55/460 (11%)

Query: 3999 SSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSI 4058
            S   +  +   ++ E T    C S           +  L++E   +++ IR L   K+ +
Sbjct: 71   SDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTEL 130

Query: 4059 SQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQ-----LDTRREKAE-YVTEI 4112
                Q+ +   +  ++ ++GE   L++    S      L+     + T+++KA+ Y+ E+
Sbjct: 131  ----QMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEEL 186

Query: 4113 TRY------------YLPELSHQKSSEAGEKADGVAS-KGDITIKVQKAKDYMQQKED-- 4157
            T+                E   +K+++  EK   V S K +I + V++ K  +++ +   
Sbjct: 187  TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL 246

Query: 4158 DEVKISAKKDIMHPEDKGLKAKKALSQDLP-----LNTKEPGKMDQEAQEQGKEDREGEE 4212
             + ++ A+ D +  E + + AK     +       LN ++  KM +  QE+  ++RE + 
Sbjct: 247  PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR--QEEKIQEREEKI 304

Query: 4213 QGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLP 4272
            Q +E++    +EK+ R+++    M  E EE+ +       Q +M  +K E+ R L   + 
Sbjct: 305  QEQEEKIREQEEKMRRQEE----MMWEKEEKMR------RQEEMMWEKEEKIRELEEKMH 354

Query: 4273 SNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAK 4332
                +         E EE +Q   +    + R ++ ++  ++   +  + +   E ++  
Sbjct: 355  EQEKIR--------EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406

Query: 4333 DYMQQK--EEDEVKISAEKDLMHPEDKDLKGKKAL-SQNLPLNPKEPGKRDGEGQEQGKE 4389
               ++K  E++E     E+++   E+K  + ++ +  Q   +  +E   R+ E   Q +E
Sbjct: 407  QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466

Query: 4390 DGEGEEQGNR-DGETEEQQQADGVGTEQEK-RDGHKSKQE 4427
            +  GE++G   + E + Q+Q + +  ++EK R+  K  +E
Sbjct: 467  EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506



 Score = 46.2 bits (108), Expect = 0.001
 Identities = 84/464 (18%), Positives = 203/464 (43%), Gaps = 81/464 (17%)

Query: 3790 QKKKEDR--ENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNL 3847
            QKKK DR  E +   +D + L+         L+R+ +  +E +  N KL++  Q  ES  
Sbjct: 175  QKKKADRYIEELTKERDALSLE---------LYRNTITDEELKEKNAKLQEKLQLVESEK 225

Query: 3848 NVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLS 3907
            + +Q       L+   L+      ++ +        +    +EL     K +  ++++  
Sbjct: 226  SEIQ-------LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN-- 276

Query: 3908 SIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVE 3967
              E    + Q+ ++++ +  EKI          ++    QE E  I+E+  K++  +E+ 
Sbjct: 277  --ELWNRLNQQQEEKMWRQEEKIQ---------EREEKIQEQEEKIREQEEKMRRQEEM- 324

Query: 3968 IWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISN 4027
            +W K                  EE MR +    + +   ++  + E+  +E+        
Sbjct: 325  MWEK------------------EEKMRRQEEMMWEKE--EKIRELEEKMHEQ-------- 356

Query: 4028 SVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLD--IKEQEKRIEHIKGEPSVLLT 4085
              +K  E   Q+E+RQ+ EKIR  +K +   ++  + +  I+EQE++I     E   ++ 
Sbjct: 357  --EKIRE---QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR----EQEEMMQ 407

Query: 4086 NACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKV 4145
                 +        +   E  E   ++ R    E   ++  +  E+ + +  + ++   +
Sbjct: 408  EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ--EEKIREQEKKIREQEEKIREQEEM---M 462

Query: 4146 QKAKDYMQQKE----DDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQ 4201
            Q+ ++ M ++E    + E K+  +++ M  +++ ++ ++   ++     +E  +M QE Q
Sbjct: 463  QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE-Q 521

Query: 4202 EQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQK 4245
            E+   ++E +   +E++    +EK+ R++++  + +  + +Q++
Sbjct: 522  EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEE 565



 Score = 45.8 bits (107), Expect = 0.001
 Identities = 65/363 (17%), Positives = 165/363 (45%), Gaps = 44/363 (12%)

Query: 3909 IEKAKHMPQKDKDRVEKALEKIMHSK-RIALEVKQPSIFQELELNIKEKGGKIQEDKEVE 3967
            +E+A       K + ++ +E++   +  ++LE+ + +I  E    +KEK  K+QE  ++ 
Sbjct: 165  LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE---ELKEKNAKLQEKLQLV 221

Query: 3968 IWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYE-KCISDNIS 4026
               K    ++            +E  R   R+    P  Q  ++ +    E + +S  + 
Sbjct: 222  ESEKSEIQLNV-----------KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 270

Query: 4027 NSVKK-ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRI-----------E 4074
              V++  L + L ++Q +KM +     + +    Q  +  I+EQE+++           E
Sbjct: 271  AQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEE 330

Query: 4075 HIKGEPSVLLTNA--CASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKA 4132
             ++ +  ++         +    H Q +  RE+ E   E  +    E   ++ ++   + 
Sbjct: 331  KMRRQEEMMWEKEEKIRELEEKMHEQ-EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389

Query: 4133 DGVASKGDITIKVQKAKDYMQQKED----DEVKISAKKDIMHPEDKGLKAK--KALSQDL 4186
            + +  + +   K+++ ++ MQ++E+     E K+  +++ M  +++ ++ +  K   Q+ 
Sbjct: 390  EKIREQEE---KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446

Query: 4187 PLNTKEPGKMDQEAQEQGKEDREGEEQGK----EDRRGAGQEKVDREDKEQGKMDHEVEE 4242
             +  +E    +QE   Q +E++ GE++GK    E +    +EK+ R++++  + + ++ E
Sbjct: 447  KIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506

Query: 4243 QQK 4245
            Q++
Sbjct: 507  QEE 509



 Score = 38.5 bits (88), Expect = 0.24
 Identities = 57/310 (18%), Positives = 117/310 (37%), Gaps = 29/310 (9%)

Query: 672 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQ--SSENSHLQL 729
           V   KK  D +I +  T   +A+S  + +   + E       K+QE LQ   SE S +QL
Sbjct: 172 VATQKKKADRYI-EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQL 230

Query: 730 SNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLIS-------------PGSK 776
            N +EL     + +   P++  Q + D L   L+  +  L                   K
Sbjct: 231 -NVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 289

Query: 777 MHKSSEELEAIKIQVNTESVNLKESKPLILNVTE-----DSDLRESEELECNTGSNITNM 831
           M +  E+++  + ++  +   ++E +  +    E     +  +R  EE+       I  +
Sbjct: 290 MWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 349

Query: 832 HQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQN 891
            +     +           +  + +     K +    ++ R      +QE+   E+E   
Sbjct: 350 EEKMHEQEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406

Query: 892 AEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKA 951
            E  +K       Q+    EQE+E   +  +  R    ++++ K ++ Q E+I       
Sbjct: 407 QEQEEKM----GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462

Query: 952 PNKEQEVQPQ 961
             +E+++  Q
Sbjct: 463 QEQEEKMGEQ 472


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
            sapiens]
          Length = 540

 Score = 57.0 bits (136), Expect = 7e-07
 Identities = 73/311 (23%), Positives = 137/311 (44%), Gaps = 36/311 (11%)

Query: 4152 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE 4211
            +  KE+ +     K++    E++ + AKK+     P+    P   ++E +   KE+ EG+
Sbjct: 106  VSMKEEKKEAAEEKEEEPEAEEEEVAAKKS-----PVKATAPEVKEEEGE---KEEEEGQ 157

Query: 4212 EQGKEDRRGA--------GQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQ 4263
            E+ +E+  GA        G EK    +KE+G+ + E E + +A+G   E+ +   +K  +
Sbjct: 158  EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE-EGETEAEAEG---EEAEAKEEKKVE 213

Query: 4264 ERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGD 4323
            E+         ++    + D ++E  E  +    P    P  +K      K+   P E  
Sbjct: 214  EK-----SEEVATKEELVADAKVEKPEKAKS---PVPKSPVEEKGKSPVPKS---PVEEK 262

Query: 4324 SASEVQKAKDYMQQKEEDEV-KISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGE 4382
              S V K+   +++K +  V K   E+    P  K    +KA S  +P +P E  K   E
Sbjct: 263  GKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSP-VPKSPVEEAKSKAE 319

Query: 4383 -GQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLT 4441
             G+ + KE+ E E +     E  E+++       ++K+     K+E V  +   ++S   
Sbjct: 320  VGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKV 379

Query: 4442 CYELNTRKEGE 4452
              E  T++EG+
Sbjct: 380  HLEKETKEEGK 390



 Score = 54.7 bits (130), Expect = 3e-06
 Identities = 87/443 (19%), Positives = 180/443 (40%), Gaps = 52/443 (11%)

Query: 3856 ASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHM 3915
            +S +  P +E  P++K V  + +      +  + E S+  E      ++   S+++ K  
Sbjct: 57   SSKIQKPKVE-APKLK-VQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 114

Query: 3916 PQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFAS 3975
              ++K+   +A E+ + +K+  ++   P + +E E   +E+ G+ +E++E E        
Sbjct: 115  AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE-EGEKEEEEGQEEEEEEDE-------- 165

Query: 3976 ISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALES 4035
                      + + EE    K  SS  +   QE  +TE  A  +         V++  E 
Sbjct: 166  -------GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 218

Query: 4036 ILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKR------IEHIKGEP---SVLLTN 4086
            +  KE+     K+   +K KS + +     ++E+ K       +E     P   S +   
Sbjct: 219  VATKEELVADAKVEKPEKAKSPVPKS---PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275

Query: 4087 ACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDIT-IKV 4145
              + +P     +          V E  +  +P+   +++    E   G   + +   +K 
Sbjct: 276  GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 335

Query: 4146 QKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAK-----KALSQDLPLNTKEPGK---MD 4197
               ++ +++KE+    +  KK    P  +   A+     K++   L   TKE GK    +
Sbjct: 336  APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 395

Query: 4198 QEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQG--- 4254
            +E ++ G E    EE   +  +G+ +E +    + +GK + E E ++K  G   E+G   
Sbjct: 396  KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 455

Query: 4255 ----------KMDGDKNEQERVL 4267
                      K  GDK+E++ V+
Sbjct: 456  NGLDLSPADEKKGGDKSEEKVVV 478



 Score = 43.9 bits (102), Expect = 0.006
 Identities = 101/538 (18%), Positives = 220/538 (40%), Gaps = 97/538 (18%)

Query: 3991 EAMRIKMRSSFSQPNLQESS-DTEKTAYEKC---ISDNISNSVKKALESILQKEQRQKME 4046
            EA ++K++  F +  ++E+  + EK+  E+    I++ ++ S+K+  +   ++++ +   
Sbjct: 66   EAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEA 125

Query: 4047 KIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKA 4106
            +   +   KS + +    ++KE+E   E  +G+                        E+ 
Sbjct: 126  EEEEVAAKKSPV-KATAPEVKEEEGEKEEEEGQ------------------------EEE 160

Query: 4107 EYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQ--KAKDYMQQKEDDEVKISA 4164
            E   E  +    E    +   + EK +G   +G+   + +  +A+   ++K +++ +  A
Sbjct: 161  EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA 220

Query: 4165 KKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMD---QEAQEQGKED---REGEEQGK--- 4215
             K+ +  + K  K +KA S       +E GK        +E+GK        EE+GK   
Sbjct: 221  TKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 280

Query: 4216 -----EDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLY 4270
                 E++  +   K   E+K +  +     E+ K+     E GK  G++ E+E      
Sbjct: 281  PKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKA---EVGK--GEQKEEEEKEVKE 335

Query: 4271 LPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQK 4330
             P          + ++E +E++   +         +K +E+  K   V    +  +  + 
Sbjct: 336  APK---------EEKVEKKEEKPKDVP-------EKKKAESPVKEEAV---AEVVTITKS 376

Query: 4331 AKDYMQQKEEDEVK-ISAEKDL--------MHPEDKDLKGKKALSQNLPLNPKEPGKRDG 4381
             K +++++ ++E K +  EK+            E  D   K +  +++ +N +  GK + 
Sbjct: 377  VKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEV 436

Query: 4382 EGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLT 4441
            E + + K  G  EE+G      +       +    EK+ G KS+++ V+           
Sbjct: 437  EQETKEKGSGREEEKGVVTNGLD-------LSPADEKKGGDKSEEKVVV---------TK 480

Query: 4442 CYELNTRKEGEEDLQGIIKSATLQLR---QQKSFDAGKIAHTKSFGVDSSNDVKTVQE 4496
              E  T + G+   + I KS T+  +    +++F+   ++  K   V S   VK V +
Sbjct: 481  TVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIVKEVTQ 538



 Score = 39.3 bits (90), Expect = 0.14
 Identities = 88/443 (19%), Positives = 178/443 (40%), Gaps = 73/443 (16%)

Query: 2811 ITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKM 2870
            + V   L+   A+ +K L G   +  +F  S      +   +Y     ++   K+ + K+
Sbjct: 12   LNVKMALDIEIAAYRKLLEGEETRFSTFAGS------ITGPLYTHRPPITISSKIQKPKV 65

Query: 2871 EKDKPKDRTC----ILPQPKLEKPLKEMQRSLSGCTDMSSILRKQE--QDIREKEQKHQS 2924
            E  K K +      I+ + K+E    EM+ +L+  T+  ++  K+E  +   EKE++ ++
Sbjct: 66   EAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEA 125

Query: 2925 ISEDISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPW 2984
              E+++     P++ ++ ++     +       EE E        E+D G          
Sbjct: 126  EEEEVAAKK-SPVKATAPEVKEEEGEKEEEEGQEEEE--------EEDEGAKSDQA---- 172

Query: 2985 EREGSKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLH 3044
            E  GS++       +G+     E +T  +   +E E  +++ +                 
Sbjct: 173  EEGGSEKEGSSEKEEGEQ---EEGETEAEAEGEEAEAKEEKKVE---------------- 213

Query: 3045 LENTGKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHK----VPA 3100
             E + +V  +E++  + K+      K  + ++   V  KG K     S V+ K    VP 
Sbjct: 214  -EKSEEVATKEELVADAKVEKPEKAKSPVPKSP--VEEKG-KSPVPKSPVEEKGKSPVPK 269

Query: 3101 EQKEQVNPDHVPESILD--SESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSK 3158
               E+     VP+S ++   +S +SK P+  ++A +   K  V             E++K
Sbjct: 270  SPVEEKGKSPVPKSPVEEKGKSPVSKSPVE-EKAKSPVPKSPV-------------EEAK 315

Query: 3159 LDITLKSNRQKMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENP-KKEGSAEEI 3217
                +    QK +  K+++        + KE   + V      +   E+P K+E  AE +
Sbjct: 316  SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV----PEKKKAESPVKEEAVAEVV 371

Query: 3218 MSSKVLSPMVEKASHEVGIPVDQ 3240
              +K +   +EK + E G P+ Q
Sbjct: 372  TITKSVKVHLEKETKEEGKPLQQ 394


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 57.0 bits (136), Expect = 7e-07
 Identities = 114/569 (20%), Positives = 221/569 (38%), Gaps = 108/569 (18%)

Query: 3910 EKAKHMPQKDKDRVEKALEKIM-HSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEI 3968
            E  + + Q+ +D  ++ L+K+   + R+ LE  + ++  EL L  +++  +++  + +  
Sbjct: 1559 ELQQDVAQRLQDSTKRELQKLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSA 1618

Query: 3969 WSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNS 4028
            +S+    +  L +    T+E E A+   + S   +    E+   E    E C+   +S  
Sbjct: 1619 FSERTLGLGPLSF----TLEDEPALSTALGSQLGE----EAEGEEFCPCEACVRKKVSPM 1670

Query: 4029 VKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNAC 4088
              KA                  +   +  I +   L    Q KR EH  GE       A 
Sbjct: 1671 SPKA-----------------TMGATRGPIKEAFDLQQILQRKRGEHTDGE-------AA 1706

Query: 4089 ASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKG-DITIKVQK 4147
               P  +H    + R     V        P LS     + GE  +G      D   K+ +
Sbjct: 1707 EVAPGKTHTDPTSTRT----VQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGE 1762

Query: 4148 AK-DYMQQKEDDEV---KISAKKDIMHPEDKG-------------------LKAKKALSQ 4184
            A+ D M Q+ + +    + SA  ++   E +G                   L+ + A   
Sbjct: 1763 AEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGG 1822

Query: 4185 DLPLNTKEPGKMD-------QEAQEQGKEDREGEEQGKED---RRGAGQEKVDREDKE-- 4232
            D     ++PG+ D        EA+ + + + EG E  + +   +   G+ + + ED E  
Sbjct: 1823 D-----QDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAP 1877

Query: 4233 --QGKMDHEVEEQQKADGVGIEQGKMDG-DKNEQERVLFLYLPSNSSLTHYILDTRIEGE 4289
              +G+   E E+ +  +     Q + +G +  E E+      P   S+    L+T  E E
Sbjct: 1878 EAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEA---QPETESVE--ALETEGEDE 1932

Query: 4290 EDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEED------EV 4343
             + +G           Q++ E  ++A G         E Q+A++  Q + ED      EV
Sbjct: 1933 PESEGA--------EAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV 1984

Query: 4344 KISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGET 4403
            +    +    PE +D++  +A  +      +   + DG    + +   EGEE    +GET
Sbjct: 1985 ETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDG---VEAQPKSEGEEAQEVEGET 2041

Query: 4404 EE-----QQQADGVGTEQEKRDGHKSKQE 4427
            ++     Q ++DGV   + + +  +++ E
Sbjct: 2042 QKTEGDAQPESDGVEAPEAEEEAQEAEGE 2070



 Score = 56.2 bits (134), Expect = 1e-06
 Identities = 67/319 (21%), Positives = 130/319 (40%), Gaps = 44/319 (13%)

Query: 4123 QKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKAL 4182
            Q++ EA ++A+G        I+ Q+A++  Q + +D   +  + +    E +        
Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEA------- 1993

Query: 4183 SQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVE- 4241
                     +P   D EA E   E +E EE+ + +  G     V+ + K +G+   EVE 
Sbjct: 1994 ---------QPESEDVEAPEAEGEMQEAEEEAQPESDG-----VEAQPKSEGEEAQEVEG 2039

Query: 4242 EQQKADGV------GIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGI 4295
            E QK +G       G+E  + + +  E E  +          +  +     EGE   +  
Sbjct: 2040 ETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPES- 2098

Query: 4296 IRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAK----DYMQQKEEDEVKISAEKDL 4351
               G+  P  +  ++  +      +EG++  E +  +    +   Q E + V+    +  
Sbjct: 2099 --EGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGE 2156

Query: 4352 MHPEDKDLKGKKALSQNLP-LNPKEPGKRDGEGQEQGK----EDGEGEEQGNRDG----E 4402
              PE + ++ ++A  +  P L   E  + +GE Q + +     + EGE Q   +G    E
Sbjct: 2157 AQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPE 2216

Query: 4403 TEEQQQADGVGTEQEKRDG 4421
             EE+ Q +  G E  + +G
Sbjct: 2217 AEEEAQPEPEGVETPEAEG 2235



 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 82/398 (20%), Positives = 159/398 (39%), Gaps = 67/398 (16%)

Query: 4038 QKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHL 4097
            +KE + + E + AL+       +    + +E E+  +  +G+            P    +
Sbjct: 1912 EKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQ----------PESEVI 1961

Query: 4098 QLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKED 4157
            +     E+A+  +E       E+  Q+       A+G A      ++  +A+  MQ+ E+
Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQE-------AEGEAQPESEDVEAPEAEGEMQEAEE 2014

Query: 4158 DEVKISAKKDIMHPEDKGLKAK-KALSQDLPLNTKEPGKMDQEAQEQ--GKEDREGEEQG 4214
            +            PE  G++A+ K+  ++      E  K + +AQ +  G E  E EE+ 
Sbjct: 2015 EA----------QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEA 2064

Query: 4215 KEDRRGAGQEKVDREDKEQGKMD-HEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPS 4273
            +E   G  QE       E   +D  E E + + +  G+E  + +G+  + E +       
Sbjct: 2065 QE-AEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI------- 2116

Query: 4274 NSSLTHYILDTRIEGEEDQQGIIRP---GILQPRHQKSSETGKKANGVP-SEGDSASEVQ 4329
                     +T  E + + +GI  P   G  QP  +       +    P SEG  A E +
Sbjct: 2117 ------EAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE 2170

Query: 4330 K-AKDYMQQKEEDEVKISAEKD---LMHPEDK-----DLKGKKALSQNLPLNPKEPGKRD 4380
            + A+  ++  E  E +  A+ +   +  PE +     +L+G +A        P+  G   
Sbjct: 2171 EEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVET 2230

Query: 4381 GEGQEQGKEDGEGEEQGNR---------DGETEEQQQA 4409
             E + + + + EGE QG +         DG++EE  ++
Sbjct: 2231 PEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASES 2268



 Score = 52.8 bits (125), Expect = 1e-05
 Identities = 69/331 (20%), Positives = 138/331 (41%), Gaps = 30/331 (9%)

Query: 4118 PELSHQKSSEA---GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDK 4174
            PE    ++ EA    ++A+G A      ++  +A+   Q + +D     A+ ++  PE +
Sbjct: 1846 PESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQ-PESE 1904

Query: 4175 GLKAKKALSQDLP-------LNTK---EPGKMDQEAQE--QGKEDREGEEQGKED--RRG 4220
            G +A +A  +  P       L T+   EP     EAQE  +  ++ EG+ Q + +     
Sbjct: 1905 GAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ 1964

Query: 4221 AGQEKVDREDKEQGKMDHEVEEQQ-----KADGVGIEQGKMDGDKNEQERVLFLYLPSNS 4275
              +E+   E ++   ++ EVE Q+     + +   +E  + +G+  E E       P + 
Sbjct: 1965 EAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEA---QPESD 2021

Query: 4276 SLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYM 4335
             +       + EGEE Q+        +   Q  S+  +         ++  EVQ+A+   
Sbjct: 2022 GVE---AQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEA 2078

Query: 4336 QQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEE 4395
              + ED     AE +   PE + ++  +A  +       E  + +GE Q + +     E 
Sbjct: 2079 HPESEDVDAQEAEGEAQ-PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEA 2137

Query: 4396 QGNRDGETEEQQQADGVGTEQEKRDGHKSKQ 4426
            +G    E+E  +  D  G  Q + +G ++++
Sbjct: 2138 EGEAQPESEGVEAQDAEGEAQPESEGIEAQE 2168



 Score = 35.8 bits (81), Expect = 1.6
 Identities = 34/145 (23%), Positives = 61/145 (42%), Gaps = 16/145 (11%)

Query: 4277 LTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQ 4336
            L    +   ++ EE ++G    G+ +   Q   E  K   G+  EG    E ++ +   Q
Sbjct: 1292 LAENTVQEEVQLEETKEGTEGEGLQEEAVQL--EETKTEEGLQEEGVQLEETKETEGEGQ 1349

Query: 4337 QKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKR---DGEGQEQG-KEDGE 4392
            Q+EE +++          E ++  G+    + + L   + G      GE  E+G KE+G 
Sbjct: 1350 QEEEAQLE----------EIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGL 1399

Query: 4393 GEEQGNRDGETEEQQQADGVGTEQE 4417
             EE      E  E    DG G++++
Sbjct: 1400 PEEGSVHGQELSEASSPDGKGSQED 1424


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 750

 Score = 56.2 bits (134), Expect = 1e-06
 Identities = 123/645 (19%), Positives = 269/645 (41%), Gaps = 114/645 (17%)

Query: 3790 QKKKEDR--ENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNL 3847
            QKKK DR  E +   +D + L+         L+R+ +  +E +  N KL++  Q  ES  
Sbjct: 187  QKKKADRYIEELTKERDALSLE---------LYRNTITDEELKEKNAKLQEKLQLVESEK 237

Query: 3848 NVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLS 3907
            + +Q       L+   L+      ++ +        +    +EL     K +  ++++  
Sbjct: 238  SEIQ-------LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN-- 288

Query: 3908 SIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVE 3967
              E    + Q+ ++++ +  EKI   +    E  Q    +E E  I+E+  K++  +E+ 
Sbjct: 289  --ELWNRLNQQQEEKMWRQEEKIQEWEEKIQE--QEEKIREQEEKIREQEEKMRRQEEM- 343

Query: 3968 IWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISN 4027
            +W K                  EE MR +    + +   ++    E+  +EK        
Sbjct: 344  MWEK------------------EEKMRRQEEMMWEKE--EKMRRQEEMMWEK------EE 377

Query: 4028 SVKKALESILQKEQ--RQKMEKIRALKKMKSSISQGIQLD-IKEQEKRIEHIKGEPSVLL 4084
             +++  E + +KE+  R+  EK+   +K++    +  + + I+EQEKR E          
Sbjct: 378  KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ--------- 428

Query: 4085 TNACASIPSPSHLQLDTRREKAEYVTEITR--YYLPELSHQKSSEAGEKADGVASKGDIT 4142
                    +    Q +  RE+ E + E  +  +   E  H++     E+           
Sbjct: 429  -------EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE----------- 470

Query: 4143 IKVQKAKDYMQQKE--DDEVKISAKKDIMHPEDKGLK--AKKALSQDLPLNTKEPGKMDQ 4198
             K Q+ ++  +Q+E   ++ +I  +K+ MH +++ ++   +K   Q+  +  +E    +Q
Sbjct: 471  -KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529

Query: 4199 EAQ--EQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKM 4256
            E +   Q ++ RE EE  +E+ +   QEK+  E+K Q + D    +++K      +  + 
Sbjct: 530  EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589

Query: 4257 DGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKAN 4316
            +    EQE               +  + +I  +E++        +Q + +K  E  +K  
Sbjct: 590  EEKIREQEE-----KRQEQEEKMWKQEEKIREQEEK--------IQEQEEKIREQEEKIR 636

Query: 4317 GVPSEGDSASEVQKAKDYMQQKE--EDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPK 4374
                E +  ++ Q+ K   Q+++  E E K+  +++ M  +++ ++      Q   +  +
Sbjct: 637  ----EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR-----EQEKKIREQ 687

Query: 4375 EPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKR 4419
            E   R+ E   Q +E+   E++     + E+ Q+ +     QE++
Sbjct: 688  EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732



 Score = 38.1 bits (87), Expect = 0.31
 Identities = 65/364 (17%), Positives = 166/364 (45%), Gaps = 30/364 (8%)

Query: 3903 DDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQE 3962
            ++ +  +E+  H  +K +++ EK  E+    ++   + ++  ++++ E  I+E+  KI+E
Sbjct: 390  EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE-KIREQEEKIRE 448

Query: 3963 DKEVEIWSKPFASISFLPYSKVGTIEG--EEAMRIKMRSSFSQPNLQESSDTEKTAYEKC 4020
             +E ++W +           K+   E   EE  R +    + Q   ++  + E+   +K 
Sbjct: 449  -QEKKMWRQE---------EKIHEQEKIREEEKRQEQEEMWRQE--EKIHEQEEIWRQKE 496

Query: 4021 ISDNISNSVKKALESILQKEQ--RQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKG 4078
                    ++K  E + ++E+  R++ EKIR  ++      + I+ + +E  +  E +  
Sbjct: 497  KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR-EQEEMWREEEKMHE 555

Query: 4079 EPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASK 4138
            +  +               Q +  RE+ E V      +  E   ++  E  ++ +    K
Sbjct: 556  QEKIWEEEKRQEQEDKMWRQEEKIREQEEKV------WRQEEKIREQEEKRQEQEEKMWK 609

Query: 4139 GDITIKVQKAKDYMQQKE--DDEVKISAKKDIMHPEDK--GLKAKKALSQDLPLNTKEPG 4194
             +  I+ Q+ K   Q+++  + E KI  ++++   +++  G + +K   Q+  +  +E  
Sbjct: 610  QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669

Query: 4195 --KMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIE 4252
              + +++ +EQ K+ RE EE+ +E      +++    ++E+   + E + Q++ + +  +
Sbjct: 670  MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729

Query: 4253 QGKM 4256
            + KM
Sbjct: 730  EEKM 733



 Score = 34.3 bits (77), Expect = 4.5
 Identities = 64/383 (16%), Positives = 168/383 (43%), Gaps = 44/383 (11%)

Query: 3888 QQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQ 3947
            Q+E+    E+  + +++ +   EK +   +K ++  EK  E+    ++ A   +Q    +
Sbjct: 382  QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQEEKIR 440

Query: 3948 ELELNIKEKGGKI--------QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRS 3999
            E E  I+E+  K+        +++K  E   +      +    K+   E EE  R K + 
Sbjct: 441  EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH--EQEEIWRQKEKM 498

Query: 4000 SFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQR--QKMEKIRALKKM--- 4054
               +  +++  +      EK         +++  E I ++E++  ++ EKIR  ++M   
Sbjct: 499  HEQEEKIRKQEEKVWRQEEK---------IREQEEKIREQEEKMWRQEEKIREQEEMWRE 549

Query: 4055 --KSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEI 4112
              K    + I  + K QE+  +  + E  +               + + +R++ E     
Sbjct: 550  EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE---- 605

Query: 4113 TRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKED----DEVKISAKKDI 4168
              +   E   ++  +  E+ + +  + +   K+++ ++  Q++E+     E K+  +++ 
Sbjct: 606  KMWKQEEKIREQEEKIQEQEEKIREQEE---KIREQEEMTQEQEEKMGEQEEKMCEQEEK 662

Query: 4169 MHPEDKGL--KAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGK----EDRRGAG 4222
            M  +++ +  + +K   Q+  +  +E    +QE   Q +E++  E++ K    E++    
Sbjct: 663  MQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722

Query: 4223 QEKVDREDKEQGKMDHEVEEQQK 4245
            +EK+ R++++  + +  + +Q++
Sbjct: 723  EEKMRRQEEKMWEQEVRLRQQEE 745


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
            protein 6 [Homo sapiens]
          Length = 724

 Score = 56.2 bits (134), Expect = 1e-06
 Identities = 82/426 (19%), Positives = 184/426 (43%), Gaps = 50/426 (11%)

Query: 4018 EKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIK 4077
            E+   +  + S++    +I  +E ++K  K++   ++  S    IQL++KE ++++E  K
Sbjct: 257  EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 316

Query: 4078 GEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVAS 4137
                 LL           HL  + +   A+   ++    L    +Q+  E   + +    
Sbjct: 317  -----LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE--- 368

Query: 4138 KGDITIKVQKAKDYMQQKE----DDEVKISAKKDIMHPEDKGL--KAKKALSQDLPLNTK 4191
                  K+Q+ ++ +Q++E    + E KI  +++ M  +++ +  K +K   Q+  +  K
Sbjct: 369  ------KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 422

Query: 4192 EPGKMDQEAQEQGKED--REGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGV 4249
            E     QE     KE+  RE EE+  E      QEK+ RE +E+ + + ++ EQ+K    
Sbjct: 423  EEKMRRQEEMMWEKEEKIRELEEKMHE------QEKI-REQEEKRQEEEKIREQEKRQEQ 475

Query: 4250 GIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSS 4309
              +  + +    EQE  +         +       R E +  +Q  IR    + + Q+  
Sbjct: 476  EAKMWRQEEKIREQEEKI---REQEEKM------WRQEEKIHEQEKIRE---EEKRQEQE 523

Query: 4310 ETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLK--------- 4360
            E  ++   +  + +   + +K  +  ++  + E K+  +++ MH +++ ++         
Sbjct: 524  EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583

Query: 4361 GKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRD 4420
             +K   Q   +  +E   R+ E   Q +E+  GE++     + E+ Q+ +     QE++ 
Sbjct: 584  EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643

Query: 4421 GHKSKQ 4426
              + K+
Sbjct: 644  REQEKK 649



 Score = 51.6 bits (122), Expect = 3e-05
 Identities = 95/498 (19%), Positives = 208/498 (41%), Gaps = 79/498 (15%)

Query: 3790 QKKKEDR--ENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDES-- 3845
            QKKK DR  E +   +D + L+         L+R+ +  +E +  N KL++  Q  ES  
Sbjct: 248  QKKKADRYIEELTKERDALSLE---------LYRNTITDEELKEKNAKLQEKLQLVESEK 298

Query: 3846 -----NLNVVQNKLCASILSPPHLEWNPR----------IKEVYMRGITRFCLSSSTQQE 3890
                 N+  ++ KL  + L  P  +              +       +    L +   Q+
Sbjct: 299  SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 358

Query: 3891 LSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELE 3950
              + M + E+ I +    I++ +   ++ ++++ +  EK+   + +  E ++    QE  
Sbjct: 359  QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 418

Query: 3951 LNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESS 4010
            +  KE+  + QE+    +W K                  EE +R        Q  ++E  
Sbjct: 419  MWEKEEKMRRQEEM---MWEK------------------EEKIRELEEKMHEQEKIREQE 457

Query: 4011 DTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGI--QLDIKE 4068
              EK   E+ I +      ++A     +++ R++ EKIR  ++      + I  Q  I+E
Sbjct: 458  --EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515

Query: 4069 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4128
            +EKR E                       Q +  RE+ E   +  + +  E   +K  E 
Sbjct: 516  EEKRQEQ-----------------EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558

Query: 4129 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4188
              + +      +  I+ Q+ K + Q     E KI  +++ +  +++ ++ ++ ++Q+   
Sbjct: 559  MWRQEEKMHDQEEKIREQEEKVWRQ-----EEKIREQEEKIREQEEKIREQEEMTQE--- 610

Query: 4189 NTKEPGKMDQEAQEQGKEDREGEEQ-GKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKAD 4247
              ++ G+ +++  EQ ++ +E EE+  +++ +   QEK  RE +E+ +   E+ ++Q+  
Sbjct: 611  QEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 670

Query: 4248 GVGIEQGKMDGDKNEQER 4265
                E+   + ++  QE+
Sbjct: 671  MWEQEEKMCEQEEKMQEQ 688



 Score = 38.9 bits (89), Expect = 0.18
 Identities = 78/494 (15%), Positives = 211/494 (42%), Gaps = 80/494 (16%)

Query: 3948 ELELNIKEKGGKIQEDK----------EVEIWSKPFASISFLPYSKVGTIEGEEAMRIKM 3997
            E++LN+KE   K++  K          E +   K   S+S    ++V      E   +  
Sbjct: 300  EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV------EENELWN 353

Query: 3998 RSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQR-QKMEKIRALKKMKS 4056
            R +  Q       + +   +E+ I +     +++  E I ++E++ ++ E++   K+ K 
Sbjct: 354  RLNQQQEEKMWRQEEKIQEWEEKIQEQ-EEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412

Query: 4057 SISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYY 4116
               + +  + +E+ +R E +  E    +             +L+ +  + E + E     
Sbjct: 413  RRQEEMMWEKEEKMRRQEEMMWEKEEKIR------------ELEEKMHEQEKIRE----- 455

Query: 4117 LPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGL 4176
              E   Q+  +  E+      +  +  + +K ++  ++  + E K+  +++ +H ++K  
Sbjct: 456  -QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR 514

Query: 4177 KAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKM 4236
            + +K   Q+     +E  +  +E   Q ++  E EE+ ++      +EK+ R++++    
Sbjct: 515  EEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ-----EEKMWRQEEKMHDQ 569

Query: 4237 DHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGII 4296
            + ++ EQ+  + V  ++ K+   + ++E++                      E++++   
Sbjct: 570  EEKIREQE--EKVWRQEEKI---REQEEKI---------------------REQEEKIRE 603

Query: 4297 RPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPED 4356
            +  + Q + +K  E  +K        +   ++Q+ ++ M+++EE   KI  ++  +  ++
Sbjct: 604  QEEMTQEQEEKMGEQEEKM------CEQEEKMQEQEEKMRRQEE---KIREQEKKIREQE 654

Query: 4357 KDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQ 4416
            + ++ ++ + Q       E  ++  E +E+ +E    +E+  R  E +  +Q   +  ++
Sbjct: 655  EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE----QEEKMRRQEEKMWEQEVRLRQQE 710

Query: 4417 EKRDGHKSKQETVL 4430
            EK   H+   E  +
Sbjct: 711  EKMQEHQEHLEAAI 724



 Score = 33.5 bits (75), Expect = 7.7
 Identities = 48/289 (16%), Positives = 110/289 (38%), Gaps = 48/289 (16%)

Query: 2644 EEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAE 2703
            E+M+RQ   +   +    +      +Q  + +  +          +E++Q  +A+    E
Sbjct: 424  EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483

Query: 2704 VDLIDQEAKINVAEE--FNPESVFFSKIHP---LQIENKKEFKTADWKTRADPKTFALPK 2758
              + +QE KI   EE  +  E     KIH    ++ E K++ +   W+            
Sbjct: 484  EKIREQEEKIREQEEKMWRQEE----KIHEQEKIREEEKRQEQEEMWR------------ 527

Query: 2759 KQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLE 2818
            +++++     IW           KI   K + K    E  MH ++ K++           
Sbjct: 528  QEEKIREQEEIWRQKEKIHEQEEKI--RKQEEKMWRQEEKMHDQEEKIR----------- 574

Query: 2819 YGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDR 2878
                          +Q++     +  +    + + +    +   +++T+ + EK   ++ 
Sbjct: 575  --------------EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620

Query: 2879 TCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISE 2927
                 + K+++  ++M+R      +    +R+QE+ IRE+E+  Q   E
Sbjct: 621  KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 669


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 57/279 (20%), Positives = 121/279 (43%), Gaps = 15/279 (5%)

Query: 4156 EDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGK 4215
            E+   +   K+ ++    +    ++   +D  L  +   +  Q+ QEQ +E  EGEEQ +
Sbjct: 97   EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156

Query: 4216 EDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNS 4275
            +  R   Q    R D+E  +   E +E+++      +     G + E+        P   
Sbjct: 157  KQER-LEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE-------FPDEE 208

Query: 4276 SL-THYILDTRIEGEEDQQGIIR---PGILQPRHQKSSETGKKANGVPSEGDSASEVQKA 4331
             L    +L+ R +G E++Q   R     + Q   +K  E  K+   +  E +   E +  
Sbjct: 209  QLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK--EWRKRETVLRKEEEKLQEEEPQ 266

Query: 4332 KDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDG 4391
            +    Q+EE++++    ++L     ++ + ++ L +   L  K+  +R  E QE+ +E  
Sbjct: 267  RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER-REQQEERREQQ 325

Query: 4392 EGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVL 4430
            E  EQ     E + +++ +    +Q +R+  + ++E  L
Sbjct: 326  ERREQQEERREQQLRREQEERREQQLRREQEEERREQQL 364



 Score = 52.0 bits (123), Expect = 2e-05
 Identities = 88/474 (18%), Positives = 183/474 (38%), Gaps = 38/474 (8%)

Query: 4014 KTAYEKCISDNISNSVKKALESILQKEQRQKME------KIRALKKMKSSISQGIQLDIK 4067
            K   E+ +   +     + LE   ++EQR K E      + + LK  +    +  QL  +
Sbjct: 591  KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650

Query: 4068 EQEKRIEHIKGEPSV-LLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSS 4126
            +QE+R + +K E     L             + +   E+ E   E  +  +P+   Q  S
Sbjct: 651  QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 710

Query: 4127 EAG----------EKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMH------ 4170
            EA            K +G   + +   K ++ +  +Q +E++      +++         
Sbjct: 711  EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770

Query: 4171 --PEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDR 4228
               E+K  + ++ LS   PL  +   ++  E ++Q ++    EE+ KE RR   +E+   
Sbjct: 771  WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830

Query: 4229 -----EDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILD 4283
                 E+++  + +   + Q++ DG+  +Q +    +  +++     L        + L 
Sbjct: 831  LQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY 890

Query: 4284 TRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEV 4343
             +   +E  +        Q   Q+  E  ++               + ++ +QQ+EE  +
Sbjct: 891  AKPALQEQLRKE------QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944

Query: 4344 KISAEKDLMHPEDKDLKGKKALSQNLP-LNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGE 4402
            +   EK      ++  +  K L Q    L  +EP KR  + +E+   + E  +Q      
Sbjct: 945  REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004

Query: 4403 TEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQ 4456
             EE+++      E++ R   + +QE    L    E      E   +   EE+LQ
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR-RLQERERQYREEEELQ 1057



 Score = 50.8 bits (120), Expect = 5e-05
 Identities = 73/472 (15%), Positives = 194/472 (41%), Gaps = 26/472 (5%)

Query: 3994 RIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKK 4053
            R+K      +  L+   +TE+   E+          K+ L+   ++E+R++  K+   ++
Sbjct: 446  RLKREQEERRDWLKREEETERHEQERR---------KQQLKRDQEEERRERWLKLEEEER 496

Query: 4054 MKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEIT 4113
             +    +  QL  +++E+R + +K +                  + + RRE+     E  
Sbjct: 497  REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556

Query: 4114 RYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPED 4173
            R        +   E  E+ D +  + +     ++ +  +++++++ ++   K++ +   +
Sbjct: 557  RLEQERREQRLKREQEERRDQLLKREE-----ERRQQRLKREQEERLEQRLKREEVERLE 611

Query: 4174 KGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQ 4233
            +  + ++ L ++ P   +    +  E QE+ ++ +   EQ +   +   +E+ +   +++
Sbjct: 612  QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671

Query: 4234 GKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQ 4293
             K +HE E +++      ++   +  K+   +  +  L S +      + +R   +E Q+
Sbjct: 672  LKREHEEERREQELAEEEQEQARERIKSRIPKWQW-QLESEADARQSKVYSRPRKQEGQR 730

Query: 4294 GIIRPGILQPRHQKSSE----TGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEK 4349
               R    + R ++ SE      ++A+    E +   +        ++ E    ++SA  
Sbjct: 731  R--RQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788

Query: 4350 DLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKED-----GEGEEQGNRDGETE 4404
             L    ++ L+ ++   +     P+E  K     Q + +E       E E+   R+   +
Sbjct: 789  PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848

Query: 4405 EQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQ 4456
             Q++ DG+  +QE+R   + +++      L  E     + L  +   +E L+
Sbjct: 849  LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900



 Score = 46.6 bits (109), Expect = 9e-04
 Identities = 93/457 (20%), Positives = 184/457 (40%), Gaps = 54/457 (11%)

Query: 4034 ESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPS 4093
            E  L++EQ+ + E+     + K    +  Q   +EQE+R + +K E     T        
Sbjct: 416  EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEE---TERHEQERR 472

Query: 4094 PSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQ 4153
               L+ D   E+ E   ++      E   ++  +   + +    + +  +K Q+ ++ +Q
Sbjct: 473  KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE---ERREQRLKRQEEEERLQ 529

Query: 4154 QKEDDEVKISAKKD------IMHPEDKGLKAKKALSQDLPLNTKEPGKMDQ-----EAQE 4202
            Q+   E ++  +++      +   E+K L+ ++   ++  L  ++  + DQ     E + 
Sbjct: 530  QRLRSEQQLRREQEERREQLLKREEEKRLEQER---REQRLKREQEERRDQLLKREEERR 586

Query: 4203 QGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEE----QQKADGVGIEQGKMDG 4258
            Q +  RE EE+ ++  +    E++++E++ + ++  E  E    QQ       E+ +   
Sbjct: 587  QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646

Query: 4259 DKNEQE--RVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKAN 4316
             + EQ+  R   L            L    E E  +Q +      Q R +  S   K   
Sbjct: 647  LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706

Query: 4317 GVPSEGDSA-----SEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPL 4371
             + SE D+      S  +K +   +++E++E +   E +L   E+     ++A  Q    
Sbjct: 707  QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE-----ERAHRQ---- 757

Query: 4372 NPKEPGKRDGEGQEQGKEDGEG-----------EEQGNRDGETEEQQQADG--VGTEQEK 4418
              +E  +RD   Q Q +E  E             EQ  R    EE+QQ +   +  E+EK
Sbjct: 758  QQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817

Query: 4419 RDGHKSKQETVLFLH-LPSESSLTCYELNTRKEGEED 4454
                + ++E    L  L  E  L   E   + + EED
Sbjct: 818  EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854



 Score = 45.8 bits (107), Expect = 0.001
 Identities = 72/429 (16%), Positives = 185/429 (43%), Gaps = 51/429 (11%)

Query: 4029 VKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNAC 4088
            +++  E  L+ E+RQ+ E+ R L + +    +  Q   +E+EK ++ ++ E  +      
Sbjct: 790  LREQRERQLRAEERQQREQ-RFLPEEEEKEQRRRQR--REREKELQFLEEEEQLQRRERA 846

Query: 4089 ASIPSPSH-LQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQK 4147
              +      LQ D  R +++      ++       Q   E   +   + +K  +  +++K
Sbjct: 847  QQLQEEEDGLQEDQERRRSQEQRRDQKW-----RWQLEEERKRRRHTLYAKPALQEQLRK 901

Query: 4148 AKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQ----------------------- 4184
             +  +Q++E++  +   +K     +++  + ++ L Q                       
Sbjct: 902  EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961

Query: 4185 -DLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQ 4243
             D  L  KE   + +E +++ +++RE ++  +E+     +E++ RE++E+ +      + 
Sbjct: 962  KDKKLQQKEEQLLGEEPEKRRRQERE-KKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020

Query: 4244 QKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQP 4303
            +K D +  E+ ++  ++ E+ R+             Y  +  ++ EE+Q  ++       
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRL-------QERERQYREEEELQQEEEQ--LLGEERETR 1071

Query: 4304 RHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKE---EDEVKISAEKDLMHPEDKDLK 4360
            R Q+     +K   +  E +     +  K   Q++E    +E ++  E++ +  E+++ +
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131

Query: 4361 GKKALSQNLPLNPKEPGKRDGE---GQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQE 4417
             ++ L +      +E  +++ E    +E  K   +  E+  R+ E  +Q++   +  EQE
Sbjct: 1132 RRQELERQ--YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQE 1189

Query: 4418 KRDGHKSKQ 4426
            KR   + +Q
Sbjct: 1190 KRRQERERQ 1198



 Score = 44.7 bits (104), Expect = 0.003
 Identities = 74/382 (19%), Positives = 160/382 (41%), Gaps = 52/382 (13%)

Query: 4030 KKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACA 4089
            K AL+  L+KEQ+   E+   L++ +    +  + + + Q +  E ++ E   LL     
Sbjct: 892  KPALQEQLRKEQQLLQEEEEELQREEREKRR--RQEQERQYREEEQLQQEEEQLLRE--- 946

Query: 4090 SIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA-GEKADGVASKGDITIKVQKA 4148
                         REK        +Y   +   QK  +  GE+ +    +     K  + 
Sbjct: 947  ------------EREKRRRQERERQYRKDKKLQQKEEQLLGEEPE--KRRRQEREKKYRE 992

Query: 4149 KDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDR 4208
            ++ +QQ+E+  ++   +K      ++  + K  L Q+     +E  +  +  QE+ ++ R
Sbjct: 993  EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE-REKRRLQERERQYR 1051

Query: 4209 EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLF 4268
            E EE  +E+ +  G+E+  R  +E  +   + EE Q+ +   + +      + E+ER   
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER--- 1108

Query: 4269 LYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEV 4328
                          +  ++ EE+Q       +L+   +K     ++   +  +     EV
Sbjct: 1109 ----------QCREEEELQQEEEQ-------LLREEREK-----RRRQELERQYREEEEV 1146

Query: 4329 QKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGK 4388
            Q+ ++ +  +EE E +   E +  + E+++L+      +   L  +E  KR  E + Q +
Sbjct: 1147 QQEEEQL-LREEPEKRRRQELERQYREEEELQ-----QEEEQLLREEQEKRRQERERQYR 1200

Query: 4389 EDGEGEEQGNRDGETEEQQQAD 4410
            E+ E + Q  +    +E Q++D
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSD 1222



 Score = 40.4 bits (93), Expect = 0.063
 Identities = 73/433 (16%), Positives = 183/433 (42%), Gaps = 26/433 (6%)

Query: 4038 QKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHL 4097
            Q+ ++++ E+ R L + +    +  +L+ +++++R E +  +                 L
Sbjct: 135  QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE-ERRAEEEQL 193

Query: 4098 QLDTRREKAEYVTE--ITRYYLPELSH----QKSSEAGEKADGVASKGDITIKVQKAKDY 4151
            Q     E  E+  E  + R  L EL      +K  +  E+ D V  + +   K  + ++ 
Sbjct: 194  QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE--KEWRKRET 251

Query: 4152 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE 4211
            + +KE+++++    +     +++  + +K   Q+L    +E  +  Q  + + +  R+ E
Sbjct: 252  VLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE 311

Query: 4212 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL 4271
            E+ +E +    +++  RE +E+ +     E+Q + +     + ++  ++ E+ R   L  
Sbjct: 312  EERREQQEERREQQERREQQEERR-----EQQLRREQEERREQQLRREQEEERREQQLRR 366

Query: 4272 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA 4331
                      L    +   +QQ      + + +  +  +  ++   +  E     E Q  
Sbjct: 367  EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426

Query: 4332 KDYMQQKEEDEVKISAEKDLMHPEDKD----LKGKKALSQNLPLNPKEPGKRDGEGQEQG 4387
            ++  +++ E + +    +  +  E ++    LK ++   ++     K+  KRD E +E+ 
Sbjct: 427  REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE-EERR 485

Query: 4388 KEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNT 4447
            +   + EE+  R+ +   +QQ      E+ ++   + ++E  L   L SE  L       
Sbjct: 486  ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL------- 538

Query: 4448 RKEGEEDLQGIIK 4460
            R+E EE  + ++K
Sbjct: 539  RREQEERREQLLK 551



 Score = 40.0 bits (92), Expect = 0.082
 Identities = 63/344 (18%), Positives = 149/344 (43%), Gaps = 39/344 (11%)

Query: 4146 QKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGK 4205
            ++ +D   ++E+ +V+   +      E K L+ ++ L Q+     +E  ++ QE +EQ  
Sbjct: 1425 RQERDRKFREEEQQVRRQER------ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478

Query: 4206 EDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQER 4265
              +E + +  E+ +   +++ DR+ +EQ     E+  Q+       E+ ++   + +++ 
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQ-----ELRSQEPERKFLEEEQQLHRQQRQRK- 1532

Query: 4266 VLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSA 4325
                +L     L       +   + D++      + Q R ++     ++      E    
Sbjct: 1533 ----FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588

Query: 4326 SEVQKAKDYMQ-----QKEEDEVKISAEKDLMHPEDKDLKGKKALSQ------NLPLNPK 4374
               ++ + +M+     +++E + ++  E+D    ED+ L  ++   Q      +     +
Sbjct: 1589 RRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648

Query: 4375 EPGKRDGEGQEQGKEDGE----GEEQGNRDGETEE--QQQADGVGTEQEKRDGHKSKQET 4428
            EP  R  E ++Q + D +     EEQ  ++GE ++  +Q+ D    E+E++   + ++  
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708

Query: 4429 VLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF 4472
                 L  E  L   EL  +   EE L+   ++   QLR+Q+ +
Sbjct: 1709 ----FLQEEQQLRRQELERKFREEEQLRQ--ETEQEQLRRQERY 1746



 Score = 38.5 bits (88), Expect = 0.24
 Identities = 70/422 (16%), Positives = 167/422 (39%), Gaps = 54/422 (12%)

Query: 4037 LQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSH 4096
            L++EQ+ + E+ R  ++ +  + +  +  +  QE+  + ++ E  +              
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508

Query: 4097 LQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKE 4156
               +  R+  E   ++ R        Q+  +   +  G   + D   K ++ +   Q++E
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568

Query: 4157 DDEVKISAKKDIMHPEDKGLK-------------------AKKALSQDLPLNTKEPGKMD 4197
            + ++    +      E++ ++                    ++ L Q+     +E  ++ 
Sbjct: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628

Query: 4198 QEAQEQG----KEDREGEEQGKEDRRGAGQEKV----DREDKEQGKMDHEVEEQQKADGV 4249
            QE +EQ     + DR+  E+  + RR   ++++    DR+ +E+ ++  E EEQQ     
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ----- 1683

Query: 4250 GIEQGKMDGDKNEQERVLFL------YLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQP 4303
             + + + D    E+E+ L        +L     L    L+ +   EE         + Q 
Sbjct: 1684 -LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ--------LRQE 1734

Query: 4304 RHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQK-----EEDEVKISAEKDLMHPEDKD 4358
              Q+     ++   +  E     E ++ +   Q++     EE++++   E+  +  ++ D
Sbjct: 1735 TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794

Query: 4359 LKGKKA--LSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQ 4416
             K ++   L Q        P +RDG+ + + ++    E++     E + Q +A+     Q
Sbjct: 1795 RKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ 1854

Query: 4417 EK 4418
            EK
Sbjct: 1855 EK 1856



 Score = 34.7 bits (78), Expect = 3.5
 Identities = 106/576 (18%), Positives = 229/576 (39%), Gaps = 82/576 (14%)

Query: 3900 QPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGK 3959
            Q  ++ L   E+ K   Q+ + +  K  E     +++  E ++    QE E   +E+   
Sbjct: 997  QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056

Query: 3960 IQEDKEVEIWSKPFASISFLP--YSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAY 4017
             QE++++    +       L   Y K   ++ EE   ++      +P  +   + E+   
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR-----EEPEKRRRQERERQCR 1111

Query: 4018 EKCISDNISNSVKKALESILQKEQRQKMEK-IRALKKMKSSISQGIQ--------LDIKE 4068
            E+   + +    ++ L    +K +RQ++E+  R  ++++    Q ++         +++ 
Sbjct: 1112 EE---EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168

Query: 4069 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPE--LSHQKSS 4126
            Q +  E ++ E   LL             + + RR++ E      R Y  E  L  QK  
Sbjct: 1169 QYREEEELQQEEEQLLRE-----------EQEKRRQERE------RQYREEEELQRQKRK 1211

Query: 4127 EAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDL 4186
            +     D    + D+  + +  K+   +      K    +     ED  L+ +++  QDL
Sbjct: 1212 QRYRDED---QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS-QQDL 1267

Query: 4187 PLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQK- 4245
                 E  + D+E + +  + R        DR    +E+++RE++++ K      +++K 
Sbjct: 1268 QHLLGEQQERDREQERRRWQQR--------DRHFPEEEQLEREEQKEAKRRDRKSQEEKQ 1319

Query: 4246 --ADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQP 4303
               +    ++ + + D+  +E    L       L     D +   EE             
Sbjct: 1320 LLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE------------L 1367

Query: 4304 RHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKK 4363
            RHQ   E G+K      E       ++ + ++  KEE +++   E++    +D+D K ++
Sbjct: 1368 RHQ---EQGRK---FLEEEQRLRRQERERKFL--KEEQQLRCQ-EREQQLRQDRDRKFRE 1418

Query: 4364 ALSQNLPLNPKEPGKRDGEGQEQGKEDGE---GEEQGNRDGETEEQQQADGVGTEQEKRD 4420
               Q L    ++   R+ E Q + +E       EEQ  R     + ++ + +  E+E++ 
Sbjct: 1419 E-EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477

Query: 4421 GHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQ 4456
             H+ +++      L  E  L   E   RK  E++L+
Sbjct: 1478 LHRQERDRKF---LEEEQQLRRQE-RDRKFREQELR 1509


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 149/749 (19%), Positives = 303/749 (40%), Gaps = 125/749 (16%)

Query: 3927 LEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFA--SISFLPYSKV 3984
            LE+ + + R AL++K   +  E     +E+   +QE  E+++        +++ L  +  
Sbjct: 1377 LEEDLRTARSALKLKNEEVESE-----RERAQALQEQGELKVAQGKALQENLALLTQTLA 1431

Query: 3985 GTIEGEEAMRIKMRSSFSQPNLQESS------DTEKTAYEKCISDNISNSVKKALESILQ 4038
               E  E +R +++    Q  +Q+++      D +K   E  +       ++K   S+L+
Sbjct: 1432 EREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKC-RSVLE 1490

Query: 4039 ------KEQRQKM----EKIRALKKMKSSISQGIQ---LDIKEQEKRIEHIKGE----PS 4081
                  +E+ QK+    E+IR L+K + +    ++   L+++++++ IE  +G+      
Sbjct: 1491 HLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKK 1550

Query: 4082 VLLTNACASIP---------------------------SPSHLQLDTRREKAEYVTEITR 4114
             L+T  C ++                            + +HL LD      E   + ++
Sbjct: 1551 QLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQ 1610

Query: 4115 YY-LPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQ---KEDDEVKISAKKDIMH 4170
             + L   S   + E  E+   V S+ +   ++Q+ K+++ Q   + D E+ +  K+ I  
Sbjct: 1611 IHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQ-KERIQV 1669

Query: 4171 PEDKGLKAKKALSQDLP---LNTKEPGKMDQEAQEQGKEDR--EGEEQGKEDRRGAGQEK 4225
             ED+  +  K L +DL    L+ +E G+ +   Q Q  ++R  EG+   K  R      K
Sbjct: 1670 LEDQRTRQTKILEEDLEQIKLSLRERGR-ELTTQRQLMQERAEEGKGPSKAQRGSLEHMK 1728

Query: 4226 VDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTR 4285
            +   DKE+     EVE QQ+     I + +   D+ EQ+            L   + +T 
Sbjct: 1729 LILRDKEK-----EVECQQEH----IHELQELKDQLEQQL---------QGLHRKVGETS 1770

Query: 4286 IEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKI 4345
            +   + +Q I+   +LQ + Q++ E G+       E    S++ +A+  + Q++++   +
Sbjct: 1771 LLLSQREQEIV---VLQQQLQEAREQGEL-----KEQSLQSQLDEAQRALAQRDQELEAL 1822

Query: 4346 SAEKDLMHPEDKDLKGKK-ALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETE 4404
              E+     +++ +K K  AL   L        +R GE Q+  ++    EE+   +G   
Sbjct: 1823 QQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRV 1882

Query: 4405 EQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTR-------------KEG 4451
            +  +        E R+  K+    +L L          +E+ TR             KE 
Sbjct: 1883 QALEEVLGDLRAESREQEKA----LLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKER 1938

Query: 4452 EEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSV 4511
            +++L+ +   +     Q+++  A   A  ++ G   +      Q    Q E+ R    S 
Sbjct: 1939 DQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEAST 1998

Query: 4512 DYIMQPEGTIFEAEQLSLPHTLNIPGSS-----------GSKTREVLTNIKEKLRHVQER 4560
               +Q      +A    L   L I                 + ++ L    E+LRH QER
Sbjct: 1999 A-TLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQER 2057

Query: 4561 KSELDVFLTIPSLSHCKLDKRTAGKKEEQ 4589
            +  L+  L      +   +K+  G++ E+
Sbjct: 2058 EQLLEKSLAQRVQENMIQEKQNLGQEREE 2086



 Score = 45.4 bits (106), Expect = 0.002
 Identities = 128/682 (18%), Positives = 282/682 (41%), Gaps = 107/682 (15%)

Query: 3836 LEKMTQEDESNLNVVQN-KLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDT 3894
            L+K  QE +     +Q  + C S+L   HL    + +E       +  +     +EL   
Sbjct: 1465 LKKRNQEVDLQQEQIQELEKCRSVLE--HLPMAVQERE------QKLTVQREQIRELEKD 1516

Query: 3895 MEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELN-I 3953
             E     ++  L  +EK   M +  + +V+   ++++  + +ALE+++     E +   I
Sbjct: 1517 RETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLI 1576

Query: 3954 KEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTE 4013
            KE  G+    +E +  +    ++     S+    +  +   ++  S+     LQE     
Sbjct: 1577 KELEGQ----RETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEV 1632

Query: 4014 KTAYEKC-----ISDNISNSV-KKALESILQKEQRQKME--KIRALKKMKSSISQGIQLD 4065
            K+  E+        ++++  + ++  E +LQKE+ Q +E  + R  K ++  + Q I+L 
Sbjct: 1633 KSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQ-IKLS 1691

Query: 4066 IKEQ-----------EKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITR 4114
            ++E+           ++R E  KG          A   S  H++L  R ++ E   E  +
Sbjct: 1692 LRERGRELTTQRQLMQERAEEGKGPSK-------AQRGSLEHMKLILRDKEKE--VECQQ 1742

Query: 4115 YYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDK 4174
             ++ EL   K  +  ++  G+        KV +    + Q+E + V +  ++ +    ++
Sbjct: 1743 EHIHELQELK-DQLEQQLQGLHR------KVGETSLLLSQREQEIVVL--QQQLQEAREQ 1793

Query: 4175 GLKAKKALSQDLPLNTKEPGKMDQ--EAQEQGKEDREGEEQGKEDRRGAGQEKVDR---- 4228
            G   +++L   L    +   + DQ  EA +Q ++  +G+E+  +++  A Q  +++    
Sbjct: 1794 GELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMT 1853

Query: 4229 -EDKEQGKMDHE-----VEEQQKADGVGIEQ-----GKMDGDKNEQERVLFLYLPSNSSL 4277
             +++     DH+     +EE+   +G  ++      G +  +  EQE+ L L L    + 
Sbjct: 1854 LKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKAL-LALQQQCA- 1911

Query: 4278 THYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQ 4337
                       E+ Q+  +    LQ       ++  +A  V  E D   E  +A+    +
Sbjct: 1912 -----------EQAQEHEVETRALQ-------DSWLQAQAVLKERDQELEALRAESQSSR 1953

Query: 4338 KEEDEVKISAE--KDLMHPEDKDLKGKK-------ALSQNLPLNPK------EPGKRDGE 4382
             +E+  +  AE  ++ +      L+GK+        LS++L  +        +  +    
Sbjct: 1954 HQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSR 2013

Query: 4383 GQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLP---SESS 4439
              E+     EGE Q       E+ QQ      ++++   H+ ++E +L   L     E+ 
Sbjct: 2014 QLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENM 2073

Query: 4440 LTCYELNTRKEGEEDLQGIIKS 4461
            +   +   ++  EE+++G+ +S
Sbjct: 2074 IQEKQNLGQEREEEEIRGLHQS 2095



 Score = 39.3 bits (90), Expect = 0.14
 Identities = 54/273 (19%), Positives = 116/273 (42%), Gaps = 23/273 (8%)

Query: 4006 LQESSDTEKTAYE--KCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQ 4063
            L ++    KTA E  K   +   N +++  E      Q++  + + +L++ K  +    +
Sbjct: 833  LAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMEL----E 888

Query: 4064 LDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEI--TRYYLPELS 4121
            + +KEQ+  +E I+ +     T A +++     +QL+T +E+   +  +  T+  L + S
Sbjct: 889  MRLKEQQTEMEAIQAQREEERTQAESAL---CQMQLETEKERVSLLETLLQTQKELADAS 945

Query: 4122 HQ----KSSEAGEKADGVASKGDITIKVQKA----KDYMQQKEDDEVKISAKKDIMHPED 4173
             Q    +     +K     + G +  ++Q+A    K+  +Q  DD   +  +   +  + 
Sbjct: 946  QQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDK 1005

Query: 4174 KGL-KAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKE 4232
              L K  + L   L         ++QE QE+ +E +E     KE  R      +   +KE
Sbjct: 1006 MDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKE 1065

Query: 4233 QGKM---DHEVEEQQKADGVGIEQGKMDGDKNE 4262
            Q  +   + +   QQ+   +  +  +  G++ E
Sbjct: 1066 QRLLVLQEADSIRQQELSALRQDMQEAQGEQKE 1098


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 111/563 (19%), Positives = 207/563 (36%), Gaps = 53/563 (9%)

Query: 4123 QKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKAL 4182
            Q SS++ +       K     K  +      +KE  + K S K      E + L+A+   
Sbjct: 211  QSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQS 270

Query: 4183 S---QDLP-------LNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKV-----D 4227
            +   +++P       L  K P K D++ ++  + +RE E      +  + Q ++      
Sbjct: 271  TVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSG 330

Query: 4228 REDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIE 4287
            R+ K +G   +    + ++             + E +R   + + S         +  I+
Sbjct: 331  RKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSG--------ERWIK 382

Query: 4288 GEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISA 4347
            G++ +   I+     P   K  +     N         SE    K+  ++K +D    S 
Sbjct: 383  GDKSELNEIKENQRSPVRVKERKITDHRN--------VSESPNRKNEKEKKVKDHKSNSK 434

Query: 4348 EKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQ------GNRDG 4401
            E+D+    +KD K K  + +      +   K   + +E+  +    EE+        RD 
Sbjct: 435  ERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDH 494

Query: 4402 ET--EEQQQADGVGTEQEK-RDGHKSKQ-ETVLFLHLPSESSLTCYELNTRKEGEEDLQG 4457
            E   E+++Q+D  G +QE+ R   KSKQ E+    H  S+S        +R    +  +G
Sbjct: 495  ENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKG 554

Query: 4458 IIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQP 4517
                 +    + +S D  +   +++   D S   K    Y+ Q+   RG++ S +    P
Sbjct: 555  KHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRS-KEYHRYREQEYRRRGRSRSRERRTPP 613

Query: 4518 EGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCK 4577
                      S         S  S+  E  +  K+K R+ + + S            + K
Sbjct: 614  ------GRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSK 667

Query: 4578 -LDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKD 4636
              D  ++    E+   R   P S   +SS   +LK   S L +   +  R+    + QK 
Sbjct: 668  SRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELK--SSMLKNKEDEKIRSSVEKENQKS 725

Query: 4637 KANISEKSVMHPEYIAVKAEKSP 4659
            K    E   +H +      E SP
Sbjct: 726  KG--QENDHVHEKNKKFDHESSP 746



 Score = 43.5 bits (101), Expect = 0.007
 Identities = 86/502 (17%), Positives = 188/502 (37%), Gaps = 58/502 (11%)

Query: 3962 EDKEVEIWSKPFASISFLPYSKV---GTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYE 4018
            E+++ +  SKPFA +  L   ++     ++ EE  R K  SS S      SSD++ ++  
Sbjct: 155  ENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSS----SSSDSDSSSDS 210

Query: 4019 KCISDN------ISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKR 4072
            +  SD+           KK  +   +  ++ K EK +  K  KS+ S+    +++ Q + 
Sbjct: 211  QSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQS 270

Query: 4073 IEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKS---SEAG 4129
                +  P +           P   + + +  + E   E         S+Q+    + +G
Sbjct: 271  TVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSG 330

Query: 4130 EKADGVASKGDITIKVQKAKDYMQQKEDD----EVKISAKKDIMHPEDKGLKAKKALSQD 4185
             K  G   +   T    +++D  ++ E      +    A++  +   ++ +K  K+   +
Sbjct: 331  RKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNE 390

Query: 4186 LPLNTKEPGKMDQ-------EAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDH 4238
            +  N + P ++ +          E      E E++ K+ +  + +  + R  ++  K  +
Sbjct: 391  IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKN 450

Query: 4239 EVEEQQKADGVGIEQGKMDG-------DKNEQERVLFLYLPSNSSLTHYILDTRIEGEED 4291
            +V+++ K+      + K          ++NE++R     + S S    +      E + D
Sbjct: 451  KVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKR-----MRSRSKGRDHENVKEKEKQSD 505

Query: 4292 QQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDL 4351
             +G            +S E  K+     +E D +    K KD   Q    E  I+  K  
Sbjct: 506  SKG------KDQERSRSKEKSKQLESKSNEHDHSK--SKEKDRRAQSRSRECDITKGKHS 557

Query: 4352 MHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADG 4411
             +   ++    +  S+ +          D +     +     E++  R G +  +++   
Sbjct: 558  YNSRTRERSRSRDRSRRV-----RSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTP 612

Query: 4412 VGTEQEK------RDGHKSKQE 4427
             G  + K      RD   S++E
Sbjct: 613  PGRSRSKDRRRRRRDSRSSERE 634


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 54.7 bits (130), Expect = 3e-06
 Identities = 111/554 (20%), Positives = 234/554 (42%), Gaps = 70/554 (12%)

Query: 3888 QQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQ 3947
            +++L++T +K  Q ++DSL+  ++ K   +K K  +EKA+ +     R  L++ +     
Sbjct: 1906 KEKLAETEKKLVQ-VEDSLAK-KQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKAL 1963

Query: 3948 ELELN-IKEKGGKIQEDKEV--------------------EIWSKPFASIS--FLPYSKV 3984
             LE+  + E+  ++ E KE                     E++ +  +      L   ++
Sbjct: 1964 NLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRI 2023

Query: 3985 GTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNIS--------NSVKKALESI 4036
              +E  E  + K+  +  Q    +       A  K I    S        N + KAL+ +
Sbjct: 2024 LAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKL 2083

Query: 4037 LQKEQRQKMEKIRA--------LKKMKSSISQGIQLDIKE---QEKRIEHIKGEPSVLLT 4085
             + E++   E+I+         +K+ + SI Q  +LDIKE    EKR E  K E    L 
Sbjct: 2084 TRDERKLTQEEIKMTKMKRALFVKERRLSIEQS-KLDIKEWDFSEKRSELTKDEKK--LA 2140

Query: 4086 NACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKV 4145
                 + +     ++   +  E  +++ R       H +     E+  G+  +  I    
Sbjct: 2141 RKQRKLANKMRRMINKEEKMTEEESKLAR------KHSEVILDDEEEGGIEEEEVIPFLK 2194

Query: 4146 QKAKDYMQQKEDDEVK--ISAKKDIMHPEDKGLKAKKALSQDLP----LNTKEPGKMDQE 4199
            ++ +   + K  D+ K   S++ D +  E+   +  ++L  +L     L+++E  + ++E
Sbjct: 2195 RRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEE 2254

Query: 4200 AQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGD 4259
             + + +E RE EE+ KE+  G  +++V++E++E+ K   E ++++  +   + + K +  
Sbjct: 2255 EEREEEEVREEEEERKEEEEGE-EKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313

Query: 4260 KNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKA---- 4315
              E+   L        S +   L+  ++ E++     +   LQ + +KS    ++     
Sbjct: 2314 SEEETESLSDEEEEEESCS---LEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSIL 2370

Query: 4316 NGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDK-DLKGKKALSQNLPLNPK 4374
             GVP     A  +   K  +++     +++  +  +  PE +   + KKA    +P   K
Sbjct: 2371 RGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKKATVVEIP--RK 2428

Query: 4375 EPGKRDGEGQEQGK 4388
              G  D E +  GK
Sbjct: 2429 FLGTMDKEREVMGK 2442



 Score = 49.3 bits (116), Expect = 1e-04
 Identities = 110/545 (20%), Positives = 235/545 (43%), Gaps = 78/545 (14%)

Query: 3909 IEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEI 3968
            IEK   + QK ++R   ++E++  +K I  + K  ++ QE + N+ ++  K+ + KE  +
Sbjct: 1806 IEKKMKLAQK-RERWINSMEELTKNKMILYQKK--NLAQEKK-NLAQEKEKLAQRKENLL 1861

Query: 3969 WSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDT----EKTAYEKCISDN 4024
            ++K   + S     ++  ++ +  M  K+ +   +   QE        EK A  +     
Sbjct: 1862 YNKERLTHS---KKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQ 1918

Query: 4025 ISNSVKKALESILQKEQRQKMEK--IRALKKMKSSIS-----QGIQLDIKE-QEKRIEHI 4076
            + +S+ K  E + Q++ +  +EK  ++  K+++  +      + + L++K   E+++  +
Sbjct: 1919 VEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLV 1978

Query: 4077 KGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPE--LSHQKSSEAGEKADG 4134
            +G+ ++    +    P  S  +  T+ E+  +  +++   L E  L H+    A E+++ 
Sbjct: 1979 EGKETL----SKGETPETSRQRKMTQVEQELFERKLS---LEEKILLHEDRILAMEESEI 2031

Query: 4135 VASKGDITI----------KVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQ 4184
               K + T           K+ KA   + +K +   K  AK +      K LKA + L++
Sbjct: 2032 AKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLN------KILKALQKLTR 2085

Query: 4185 DLPLNTKEPGKMDQEAQEQG-KEDREGEEQGKED-RRGAGQEKVDREDKEQGKMDHEVEE 4242
            D    T+E  KM +  +    KE R   EQ K D +     EK     K++ K+     +
Sbjct: 2086 DERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKL---ARK 2142

Query: 4243 QQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQ 4302
            Q+K         KM    N++E++           +  ILD   EG  +++ +I    L+
Sbjct: 2143 QRKL------ANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIP--FLK 2194

Query: 4303 PRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGK 4362
             R +K  E  +             EV+  + + ++ E    ++  ++ L   E+++ +  
Sbjct: 2195 RRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEERE-- 2252

Query: 4363 KALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGH 4422
                               E +E+ +E+   EE+  ++ E  E++Q +    E++K+   
Sbjct: 2253 -------------------EEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293

Query: 4423 KSKQE 4427
            K K+E
Sbjct: 2294 KKKEE 2298



 Score = 34.7 bits (78), Expect = 3.5
 Identities = 61/278 (21%), Positives = 120/278 (43%), Gaps = 60/278 (21%)

Query: 4141 ITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEA 4200
            +T +V + K+ M ++E+   K +  +D++  E+  +  KK       +   EPG +    
Sbjct: 1332 VTQEVIRHKEVMPREEEQAQKKA--RDMLGLEETQVILKKGKK----VIFLEPGNVTMGK 1385

Query: 4201 QEQGKEDREGEEQGKEDRRGAGQE-----KVDRE-DKEQGKMDHEVEEQQKADGVGIEQG 4254
            +   KE+++  ++  +  R A Q+     K+ RE  KE+  M  EVEE    +   ++Q 
Sbjct: 1386 EISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQ- 1444

Query: 4255 KMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKK 4314
                   E + V+    PS                                +K+ +  K+
Sbjct: 1445 -------EGKLVMIERTPSWQDW----------------------------KKAWDEWKQ 1469

Query: 4315 ANGVPSEGDSASEVQKAKDYMQQKE---EDEVKISAEKDLMHPEDKDLKGK--KALSQNL 4369
             +G   +   A + +  K  +Q++E   +   K+S E++++  EDK LK +  K + +N+
Sbjct: 1470 VHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQ-EDKKLKWEEWKQVWENM 1528

Query: 4370 PLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQ 4407
                     +  E Q + +E+   EE+ +R+GE +EQQ
Sbjct: 1529 L------SSKSKEQQYKDEEEVTLEEEVSREGEEKEQQ 1560



 Score = 33.5 bits (75), Expect = 7.7
 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 8/63 (12%)

Query: 5330 KRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRG---TDITLK 5386
            K+PI      I E   RE ++  + ++V   K+ +P++EE+ QKK  DM G   T + LK
Sbjct: 1314 KKPIF-----IQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILK 1368

Query: 5387 SKK 5389
              K
Sbjct: 1369 KGK 1371


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 54.7 bits (130), Expect = 3e-06
 Identities = 90/444 (20%), Positives = 184/444 (41%), Gaps = 55/444 (12%)

Query: 4011 DTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQE 4070
            + E+ AY++   D+   + ++      Q+  RQK E+  +L ++   +    Q  + ++E
Sbjct: 21   EAERIAYQRN-DDDEEEAARERRRRARQERLRQKQEE-ESLGQVTDQVEVNAQNSVPDEE 78

Query: 4071 KRIE----HIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSS 4126
             +       ++G+         A        + + R+++ +   E  + + P ++    S
Sbjct: 79   AKTTTTNTQVEGDDEAAFLERLAR-------REERRQKRLQEALERQKEFDPTITDASLS 131

Query: 4127 EAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDL 4186
                +     ++ + T K +K++   ++ E +E +   K             +K   +D 
Sbjct: 132  LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKS-----------YQKNDWRDA 180

Query: 4187 PLNTKEPGKMDQEAQEQGKEDREGEEQGKE--DRRGAGQEKVDREDKEQGKMDHEVEEQQ 4244
              N KE  + ++E +E+ K    GE QG+E   +  A +EK+ +EDK   K +   +E+ 
Sbjct: 181  EENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKL-QEDKPTFKKEEIKDEKI 239

Query: 4245 KADGVGIEQGK--MDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQ 4302
            K D    E+ K  MD  K   E    +   +   +TH +  T       +    RPG   
Sbjct: 240  KKDKEPKEEVKSFMDRKKGFTE----VKSQNGEFMTHKLKHT-------ENTFSRPG--- 285

Query: 4303 PRHQKSSETGKKANGVP--SEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLK 4360
                ++S   K+A G P    G    E+++ +   + +E +++K   ++  +  E ++LK
Sbjct: 286  ---GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL--ELEELK 340

Query: 4361 GKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRD 4420
             KK   +   L  +E  ++  E   + +E    EE+  R  E  E+++A+     Q+  +
Sbjct: 341  -KKREERRKVLEEEEQRRKQEEADRKLRE----EEEKRRLKEEIERRRAEAAEKRQKMPE 395

Query: 4421 GHKSKQETVLFLHLPSESSLTCYE 4444
               S  +       P  SSL   E
Sbjct: 396  DGLSDDKKPFKCFTPKGSSLKIEE 419


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
            6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 53.9 bits (128), Expect = 6e-06
 Identities = 107/557 (19%), Positives = 238/557 (42%), Gaps = 68/557 (12%)

Query: 3903 DDSLSSIEKAKHMPQK---------DKDRVEKALEKIMHSKRIALEVKQPSIFQELELNI 3953
            DD L   E +K   +          D + +E A   + H K+ + EVK  S F++ +  +
Sbjct: 87   DDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA--GVSHVKKNSDEVK--SSFKKRQEKM 142

Query: 3954 KEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTE 4013
             EK    +  K V I  KP+  +            GE   + +  +S  +  L       
Sbjct: 143  NEKNYTFR--KRVVI-KKPWLRL------------GEVTAQKRPENSLLEETLHFDHAVR 187

Query: 4014 KTAY-EKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKR 4072
               Y EK   +  + S++    +I  +E ++K  +++   ++  S    IQL++K+ +++
Sbjct: 188  MGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK 247

Query: 4073 IEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAG--- 4129
            +E  +    +LL      + +   L  + +   A+   ++    L  L +Q+  E     
Sbjct: 248  LERAQ----LLLPQQQLQVEA-DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302

Query: 4130 ----EKADGVASKGDITIKVQKAKDYMQQKE--DDEVKISAKKDIMHPEDKGLKAK--KA 4181
                ++ +    + ++ I+ Q+ K + Q+++  + E KI  ++D M  +++ ++ +  K 
Sbjct: 303  EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKI 362

Query: 4182 LSQDLPLNTKEPG--KMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHE 4239
              Q+  +  +E    + D++ QEQ +E    EE+ +E      QEK+ R++K+  + D +
Sbjct: 363  REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR-QEKMWRQEKKMREQDEK 421

Query: 4240 VEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIR-P 4298
            + EQ++      E  + +    E E ++         +   + +   + +E ++ I R  
Sbjct: 422  IREQEE------EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475

Query: 4299 GILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKE----EDEVKISAEKDLMHP 4354
              +Q + +K+    K         +   ++ + ++ M ++E    E E K+  +++ M  
Sbjct: 476  EKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535

Query: 4355 EDKDLKGKKALSQNLPLNPKEPGKRDGE-GQEQGKEDGEGEEQGNRDGET--------EE 4405
            ++  L  ++   Q   +  +E  +R G+ GQ+     G G E G++   T         +
Sbjct: 536  QEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELK 595

Query: 4406 QQQADGVGTEQEKRDGH 4422
             Q+A  +  +Q+   GH
Sbjct: 596  SQEAQSLQQQQDHYRGH 612


>gi|4557509 cylicin 2 [Homo sapiens]
          Length = 348

 Score = 53.5 bits (127), Expect = 7e-06
 Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 64/287 (22%)

Query: 4124 KSSEAGEKADGVASKGDITIKV----------QKAKDYMQQKEDDEVKISAKKDIMHPED 4173
            K++E G+K +   ++ D T             +K KD  + KE+   K+ AKKD    + 
Sbjct: 110  KAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEE---KLDAKKDSKKGKK 166

Query: 4174 KGLKAKKAL--SQDLPLNTKEPGKMDQEAQEQGKE---DREGEEQGKEDRRGAGQEKVDR 4228
               K K +   S+D     K+  K D++   +GK+   + EGE+ G E        K  +
Sbjct: 167  DAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEK-----DSKKGK 221

Query: 4229 EDKEQGKMDHEVEEQQ-KADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIE 4287
            +D ++GK D  +E Q  KAD    E GK D +K ++ +                     +
Sbjct: 222  KDSKKGK-DSAIELQAVKADEKKDEDGKKDANKGDESK---------------------D 259

Query: 4288 GEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISA 4347
             ++D + I              + GKK    PS  DS S+    K+  +   +D  K+ A
Sbjct: 260  AKKDAKEI--------------KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKV-A 304

Query: 4348 EKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGE 4394
            +KD    E +    KK   +N   + K+  K++ +  E+     +G+
Sbjct: 305  KKD---TEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348



 Score = 46.6 bits (109), Expect = 9e-04
 Identities = 56/272 (20%), Positives = 118/272 (43%), Gaps = 43/272 (15%)

Query: 4187 PLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKA 4246
            PL      ++D +A E GK+  +   Q K+      + K  ++D ++GK D E  +++K 
Sbjct: 98   PLKPTRTVEVDSKAAEIGKKGEDKTTQ-KDTTDSESELKQGKKDSKKGK-DIEKGKEEKL 155

Query: 4247 DGV-GIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRH 4305
            D     ++GK D +K +                    D+  E E+++ G  +      + 
Sbjct: 156  DAKKDSKKGKKDAEKGK--------------------DSATESEDEKGGAKKDN---KKD 192

Query: 4306 QKSSETGKKANGVPSEGDSAS---EVQKAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGK 4362
            +K S  GK +    SEG+      + +K K   ++ ++  +++ A K     E KD  GK
Sbjct: 193  KKDSNKGKDS-ATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKA---DEKKDEDGK 248

Query: 4363 KALSQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGH 4422
            K  ++    +  +  K+D +  ++GK+D +     + D + + ++++    T+  K+   
Sbjct: 249  KDANKG---DESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAK 305

Query: 4423 KSKQETVLFLHLPSESSLTCYELNTRKEGEED 4454
            K  ++        S  S    + N +K+ ++D
Sbjct: 306  KDTEK-------ESADSKKDAKKNAKKDAKKD 330



 Score = 39.3 bits (90), Expect = 0.14
 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 32/218 (14%)

Query: 4307 KSSETGKKANGVPSE---GDSASEV-------QKAKDYMQQKEEDEVKISAEKDLMHPED 4356
            K++E GKK     ++    DS SE+       +K KD  + KEE   K+ A+KD    + 
Sbjct: 110  KAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEE---KLDAKKDSKKGKK 166

Query: 4357 KDLKGKKAL--SQNLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGT 4414
               KGK +   S++     K+  K+D +   +GK D   E +G + G  ++ ++      
Sbjct: 167  DAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGK-DSATESEGEKGGTEKDSKKG----- 220

Query: 4415 EQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDA 4474
               K+D  K K   +    + ++            +G+E      K    ++++ K  D 
Sbjct: 221  ---KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDA--KKDAKEIKKGKK-DK 274

Query: 4475 GKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVD 4512
             K + T S   DS +DVK  +E K     D  K    D
Sbjct: 275  KKPSSTDS---DSKDDVK--KESKKDATKDAKKVAKKD 307


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 274,021,052
Number of Sequences: 37866
Number of extensions: 13157294
Number of successful extensions: 50567
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 730
Number of HSP's that attempted gapping in prelim test: 38436
Number of HSP's gapped (non-prelim): 8838
length of query: 7081
length of database: 18,247,518
effective HSP length: 127
effective length of query: 6954
effective length of database: 13,438,536
effective search space: 93451579344
effective search space used: 93451579344
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 75 (33.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.