Search of human proteins with 225903385

Search of human proteins with 225903385

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
sapiens]
         (309 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo sap...   631   0.0  
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]   619   e-178
gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]            236   2e-62
gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]            225   4e-59
gi|32307152 oxytocin receptor [Homo sapiens]                          221   6e-58
gi|46395496 G protein-coupled receptor for asthma susceptibility...   124   1e-28
gi|46391085 G protein-coupled receptor for asthma susceptibility...   124   1e-28
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho...    92   8e-19
gi|4557865 somatostatin receptor 5 [Homo sapiens]                      89   6e-18
gi|28875799 cholecystokinin B receptor [Homo sapiens]                  86   3e-17
gi|167000885 galanin receptor 1 [Homo sapiens]                         84   2e-16
gi|149944554 somatostatin receptor 4 [Homo sapiens]                    82   8e-16
gi|40385873 G protein-coupled receptor 150 [Homo sapiens]              81   1e-15
gi|222080109 orexin receptor 2 [Homo sapiens]                          80   3e-15
gi|4502607 cholecystokinin A receptor [Homo sapiens]                   80   3e-15
gi|20373179 G protein-coupled receptor 73 [Homo sapiens]               79   7e-15
gi|21426829 prokineticin receptor 2 [Homo sapiens]                     78   1e-14
gi|218563730 chemokine (C-X-C motif) receptor 3 isoform B [Homo ...    77   1e-14
gi|4504099 chemokine (C-X-C motif) receptor 3 isoform A [Homo sa...    77   1e-14
gi|9506745 urotensin 2 receptor [Homo sapiens]                         77   3e-14
gi|4503905 galanin receptor 2 [Homo sapiens]                           76   4e-14
gi|4557857 somatostatin receptor 1 [Homo sapiens]                      74   2e-13
gi|31881792 leukotriene B4 receptor [Homo sapiens]                     72   5e-13
gi|222080095 orexin receptor 1 [Homo sapiens]                          72   5e-13
gi|221218998 leukotriene B4 receptor [Homo sapiens]                    72   5e-13
gi|63477962 opioid receptor, delta 1 [Homo sapiens]                    72   6e-13
gi|4505513 opiate receptor-like 1 [Homo sapiens]                       70   2e-12
gi|33286424 opiate receptor-like 1 [Homo sapiens]                      70   2e-12
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]       70   3e-12
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]        70   3e-12

>gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
           sapiens]
          Length = 309

 Score =  631 bits (1627), Expect = 0.0
 Identities = 309/309 (100%), Positives = 309/309 (100%)

Query: 1   MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA 60
           MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
Sbjct: 1   MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA 60

Query: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120
           ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
Sbjct: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120

Query: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180
           VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
Sbjct: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180

Query: 181 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP 240
           RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
Sbjct: 181 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP 240

Query: 241 SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA 300
           SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
Sbjct: 241 SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA 300

Query: 301 PLEGGCSRG 309
           PLEGGCSRG
Sbjct: 301 PLEGGCSRG 309


>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
          Length = 371

 Score =  619 bits (1597), Expect = e-178
 Identities = 304/304 (100%), Positives = 304/304 (100%)

Query: 1   MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA 60
           MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
Sbjct: 1   MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA 60

Query: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120
           ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
Sbjct: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120

Query: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180
           VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
Sbjct: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180

Query: 181 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP 240
           RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
Sbjct: 181 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP 240

Query: 241 SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA 300
           SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
Sbjct: 241 SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA 300

Query: 301 PLEG 304
           PLEG
Sbjct: 301 PLEG 304


>gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]
          Length = 424

 Score =  236 bits (601), Expect = 2e-62
 Identities = 134/290 (46%), Positives = 173/290 (59%), Gaps = 23/290 (7%)

Query: 32  RDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALF 91
           RD  LA+ E+ +L+ V V     N  VL  L + GR+   + +H+F+ HL L DLAVALF
Sbjct: 29  RDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKR--SRMHLFVLHLALTDLAVALF 86

Query: 92  QVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHG 151
           QVLPQL W  T RF+GPD LCRAVKYLQ++ M+AS+YM+LAMTLDR+ A+C P+ + +  
Sbjct: 87  QVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQ- 145

Query: 152 SGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIAL 211
            G      +   W  + + SLPQ+FIF+ R V  GSGV DCWA F  PWG R Y+TW  L
Sbjct: 146 PGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTL 205

Query: 212 MVFVAPTLGIAACQVLIFREIHASL-VPGPSERPGGRRRGRRT--------------GSP 256
            +FV P   + AC  LI  EI  +L V   + R GG   G RT              G P
Sbjct: 206 AIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGG--GGWRTWDRPSPSTLAATTRGLP 263

Query: 257 GEGAH---VSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLE 303
              +    +S A  +TV+MT VIV+ Y+ CWAPFF VQ+W+ WD  AP E
Sbjct: 264 SRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDE 313


>gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]
          Length = 418

 Score =  225 bits (573), Expect = 4e-59
 Identities = 118/292 (40%), Positives = 162/292 (55%), Gaps = 36/292 (12%)

Query: 28  PLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLA 87
           P D R+  LA+ E+A+L++ F    L N  VL AL R  R+   + +H+FI HL LADLA
Sbjct: 42  PRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKT--SRMHLFIRHLSLADLA 99

Query: 88  VALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLA 147
           VA FQVLPQ+ W  T RFRGPD LCR VK+LQ+ GM+AS+YM++ MT DR+ A+C P+  
Sbjct: 100 VAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKT 159

Query: 148 YRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVT 207
            +          +  AW  S +LS PQ F+F+   V   +   DCWA F +PWG R YVT
Sbjct: 160 LQQ-PARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVT 218

Query: 208 WIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAH------ 261
           W+   +FVAP + +  C   I   I  ++            RG+      +GA       
Sbjct: 219 WMTGGIFVAPVVILGTCYGFICYNIWCNV------------RGKTASRQSKGAEQAGVAF 266

Query: 262 ---------------VSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDP 298
                          +S A  +TV+MT VIV  Y++CWAPFF++Q+W+ WDP
Sbjct: 267 QKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDP 318


>gi|32307152 oxytocin receptor [Homo sapiens]
          Length = 389

 Score =  221 bits (563), Expect = 6e-58
 Identities = 130/312 (41%), Positives = 177/312 (56%), Gaps = 29/312 (9%)

Query: 4   ASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALA 63
           A+  SA P     P    N +   P   R+  LAR E+A+L ++ +     N  VL AL 
Sbjct: 13  AANASAAP-----PGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNACVLLAL- 64

Query: 64  RRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGM 123
           R  R+ H + +  F+ HL +ADL VA+FQVLPQL W  T RF GPD LCR VKYLQ+VGM
Sbjct: 65  RTTRQKH-SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGM 123

Query: 124 YASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNV 183
           +AS+Y++L M+LDR  AIC+P+ + R  +       VL  W   L+ S PQ+ IF+ R V
Sbjct: 124 FASTYLLLLMSLDRCLAICQPLRSLRRRTD---RLAVLATWLGCLVASAPQVHIFSLREV 180

Query: 184 EGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL------- 236
               GV DCWA F +PWG + Y+TWI L V++ P + +AAC  LI  +I  +L       
Sbjct: 181 --ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAA 238

Query: 237 -----VPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQ 291
                  G +   GGR    R  S      +S A  +TV+MT +IV+ +++CW PFF VQ
Sbjct: 239 AAAEAPEGAAAGDGGRVALARVSSV---KLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQ 295

Query: 292 LWAAWDPEAPLE 303
           +W+ WD  AP E
Sbjct: 296 MWSVWDANAPKE 307


>gi|46395496 G protein-coupled receptor for asthma susceptibility
           isoform A [Homo sapiens]
          Length = 371

 Score =  124 bits (311), Expect = 1e-28
 Identities = 72/259 (27%), Positives = 134/259 (51%), Gaps = 21/259 (8%)

Query: 40  ELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAW 99
           +L  L ++FV   + N +VL +  RR ++        F+  L + D    L  +L  + W
Sbjct: 52  QLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMT---FFVTQLAITDSFTGLVNILTDINW 108

Query: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
           + T  F  PD +CR V+YLQ+V +YAS+Y+++++++DR+ AI  PM   +    A     
Sbjct: 109 RFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQA--RVL 166

Query: 160 VLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTL 219
           +++AW+ S L S+P L IF +R +  G     CWA + +      Y+T +A +V+  P  
Sbjct: 167 IVIAWSLSFLFSIPTLIIFGKRTLSNGE--VQCWALWPDDSYWTPYMTIVAFLVYFIPLT 224

Query: 220 GIAACQVLIFREI------HASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
            I+    ++ R I      + +++   S+       G+   S   G  +S A  K ++ +
Sbjct: 225 IISIMYGIVIRTIWIKSKTYETVISNCSD-------GKLCSSYNRGL-ISKAKIKAIKYS 276

Query: 274 LVIVVVYVLCWAPFFLVQL 292
           ++I++ ++ CW+P+FL  +
Sbjct: 277 IIIILAFICCWSPYFLFDI 295


>gi|46391085 G protein-coupled receptor for asthma susceptibility
           isoform B [Homo sapiens]
          Length = 377

 Score =  124 bits (311), Expect = 1e-28
 Identities = 72/259 (27%), Positives = 134/259 (51%), Gaps = 21/259 (8%)

Query: 40  ELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAW 99
           +L  L ++FV   + N +VL +  RR ++        F+  L + D    L  +L  + W
Sbjct: 52  QLITLWVLFVFTIVGNSVVLFSTWRRKKKSRMT---FFVTQLAITDSFTGLVNILTDINW 108

Query: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
           + T  F  PD +CR V+YLQ+V +YAS+Y+++++++DR+ AI  PM   +    A     
Sbjct: 109 RFTGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQA--RVL 166

Query: 160 VLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTL 219
           +++AW+ S L S+P L IF +R +  G     CWA + +      Y+T +A +V+  P  
Sbjct: 167 IVIAWSLSFLFSIPTLIIFGKRTLSNGE--VQCWALWPDDSYWTPYMTIVAFLVYFIPLT 224

Query: 220 GIAACQVLIFREI------HASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
            I+    ++ R I      + +++   S+       G+   S   G  +S A  K ++ +
Sbjct: 225 IISIMYGIVIRTIWIKSKTYETVISNCSD-------GKLCSSYNRGL-ISKAKIKAIKYS 276

Query: 274 LVIVVVYVLCWAPFFLVQL 292
           ++I++ ++ CW+P+FL  +
Sbjct: 277 IIIILAFICCWSPYFLFDI 295


>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
           sapiens]
          Length = 328

 Score = 91.7 bits (226), Expect = 8e-19
 Identities = 70/266 (26%), Positives = 125/266 (46%), Gaps = 22/266 (8%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGH-WAPIHVFIGHLCLADLAVALFQVLPQLAW 99
           L LLS  F A  L   L L    ++  +G   + + + + HL LA+L   L  +     W
Sbjct: 45  LFLLSATFNASFL---LKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMW 101

Query: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
             T ++   + LC+ + YL++  MYA ++M++ ++LDR  AI RP LA +  S    +  
Sbjct: 102 NITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRP-LALKSNSKVGQSM- 159

Query: 160 VLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWA------CFAEPWGRRTYVTWIALMV 213
           V +AW  S + + PQL+IF   ++   SG T  ++       F++ W +  Y  +    +
Sbjct: 160 VGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCL 219

Query: 214 FVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
           F+ P   +  C   I   +   L   P E    + +           ++  A  KT++MT
Sbjct: 220 FIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKN----------NIPRARLKTLKMT 269

Query: 274 LVIVVVYVLCWAPFFLVQLWAAWDPE 299
           +     + +CW P++++ +W  +DPE
Sbjct: 270 VAFATSFTVCWTPYYVLGIWYWFDPE 295


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score = 88.6 bits (218), Expect = 6e-18
 Identities = 96/309 (31%), Positives = 139/309 (44%), Gaps = 57/309 (18%)

Query: 15  SLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALS----NGLVLAALARRGRRGH 70
           S P   S     R L    P  A A   L+ ++++ V  +    N LV+  + R  +   
Sbjct: 15  SSPGAASGGGDNRTLVGPAPS-AGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMK- 72

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFR--GPDALCRAVKYLQMVGMYASSY 128
               +++I +L +AD+   L   LP LA +    F   GP  LCR V  L  V  + S +
Sbjct: 73  -TVTNIYILNLAVADVLYMLG--LPFLATQNAASFWPFGP-VLCRLVMTLDGVNQFTSVF 128

Query: 129 MILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLV------AWAFSLLLSLPQLFIFAQRN 182
            +  M++DR+ A+  P+      S A W RP +       AW  SL +SLP L +FA   
Sbjct: 129 CLTVMSVDRYLAVVHPL------SSARWRRPRVAKLASAAAWVLSLCMSLP-LLVFADVQ 181

Query: 183 VEGGSGVTDCWACFAEP---WGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPG 239
            EGG+    C A + EP   WG   ++ + A++ F AP L I  C +LI  ++ A+ V  
Sbjct: 182 -EGGT----CNASWPEPVGLWGA-VFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGV-- 233

Query: 240 PSERPGG-RRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQL--WAAW 296
              R G  RRR  R               K  RM LV+V+V+  CW PFF V +   A  
Sbjct: 234 ---RVGCVRRRSER---------------KVTRMVLVVVLVFAGCWLPFFTVNIVNLAVA 275

Query: 297 DPEAPLEGG 305
            P+ P   G
Sbjct: 276 LPQEPASAG 284


>gi|28875799 cholecystokinin B receptor [Homo sapiens]
          Length = 447

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 93/347 (26%), Positives = 143/347 (41%), Gaps = 71/347 (20%)

Query: 11  PGHPSLPSLP-SNSSQERP----LDTRDPLLARAELALLSIVFVAVALSNGLVLAAL--A 63
           PG P L S    N S E P      TR+  LA   + L +++F+     N L++  L  +
Sbjct: 24  PGAPLLNSSSVGNLSCEPPRIRGAGTRELELA-IRITLYAVIFLMSVGGNMLIIVVLGLS 82

Query: 64  RRGRRGHWAPIHVFIGHLCLADLAVAL----FQVLPQLAWKATDRFRGPDALCRAVKYLQ 119
           RR R       + F+  L ++DL +A+    F +LP L       F     +C+AV YL 
Sbjct: 83  RRLR----TVTNAFLLSLAVSDLLLAVACMPFTLLPNLM----GTFIFGTVICKAVSYLM 134

Query: 120 MVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFA 179
            V +  S+  ++A+ L+R+ AICRP+ A    + +H  R ++  W  S LL +P      
Sbjct: 135 GVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTV 194

Query: 180 QRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL--- 236
            + V  G  V  C   +     R+T+   + L++F  P + +A    LI RE++  L   
Sbjct: 195 VQPV--GPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFD 252

Query: 237 ----------------VPG--------------------------PSERPGGRRRGRRTG 254
                           +PG                          P  RP          
Sbjct: 253 GDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAP 312

Query: 255 SPGEGAHVS----AAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWD 297
            PG G+  +     A  + VRM LVIVV++ LCW P +    W A+D
Sbjct: 313 GPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFD 359


>gi|167000885 galanin receptor 1 [Homo sapiens]
          Length = 349

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 67/261 (25%), Positives = 113/261 (43%), Gaps = 34/261 (13%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWK 100
           L +  ++F    L N LV+  LAR       +  ++FI +L +ADLA  LF +  Q    
Sbjct: 37  LVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVY 96

Query: 101 ATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPV 160
           A   +     +C+ + Y   V M  S + + AM++DR+ AI       R  S    +R  
Sbjct: 97  ALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHS----RRSSSLRVSRNA 152

Query: 161 LVA----WAFSLLLSLPQLF---IFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMV 213
           L+     WA S+ ++ P  +   +F  R     S  T CW  + +P  ++ YV    +  
Sbjct: 153 LLGVGCIWALSIAMASPVAYHQGLFHPR----ASNQTFCWEQWPDPRHKKAYVVCTFVFG 208

Query: 214 FVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
           ++ P L I  C   +   +H  L          +   +++          A+  KT +  
Sbjct: 209 YLLPLLLICFCYAKVLNHLHKKL----------KNMSKKS---------EASKKKTAQTV 249

Query: 274 LVIVVVYVLCWAPFFLVQLWA 294
           LV+VVV+ + W P  ++ LWA
Sbjct: 250 LVVVVVFGISWLPHHIIHLWA 270


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score = 81.6 bits (200), Expect = 8e-16
 Identities = 72/254 (28%), Positives = 121/254 (47%), Gaps = 30/254 (11%)

Query: 43  LLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQV-LPQLAWKA 101
           + ++V +   + N LV+  + R  +       ++++ +L +AD    LF + +P +A  A
Sbjct: 53  IYALVCLVGLVGNALVIFVILRYAKMK--TATNIYLLNLAVAD---ELFMLSVPFVASSA 107

Query: 102 TDR-FRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLA--YRHGSGAHWNR 158
             R +     LCRAV  +  + M+ S + +  +++DR+ A+  P+ A  YR  S A    
Sbjct: 108 ALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLIN 167

Query: 159 PVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPT 218
             L  W  SLL++LP       R   GG  V  C   +  P     +V +  L+ F+ P 
Sbjct: 168 --LGVWLASLLVTLPIAIFADTRPARGGQAVA-CNLQWPHPAWSAVFVVYTFLLGFLLPV 224

Query: 219 LGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVV 278
           L I  C +LI  ++ A  +     R G ++R R             +  K  R+ L++VV
Sbjct: 225 LAIGLCYLLIVGKMRAVAL-----RAGWQQRRR-------------SEKKITRLVLMVVV 266

Query: 279 VYVLCWAPFFLVQL 292
           V+VLCW PF++VQL
Sbjct: 267 VFVLCWMPFYVVQL 280


>gi|40385873 G protein-coupled receptor 150 [Homo sapiens]
          Length = 434

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 83/304 (27%), Positives = 122/304 (40%), Gaps = 45/304 (14%)

Query: 34  PLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWA-----PIHVFIGHLCLADLAV 88
           P   R  L  L ++ V     N  VL  L   G  G WA      +   +  L LADL  
Sbjct: 39  PPSRRVRLVFLGVILVVAVAGNTTVLCRLCGGG--GPWAGPKRRKMDFLLVQLALADLYA 96

Query: 89  ALFQVLPQLAWKATDRFRGP--DALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPML 146
                L QLAW+     R    D  CR ++ LQ  G  AS+++++ + L+R RA+  P  
Sbjct: 97  CGGTALSQLAWELLGEPRAATGDLACRFLQLLQASGRGASAHLVVLIALERRRAVRLP-- 154

Query: 147 AYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIF--------------------AQRNVEGG 186
              HG          + W  +LLL+LP  F+                     A       
Sbjct: 155 ---HGRPLPARALAALGWLLALLLALPPAFVVRGDSPSPLPPPPPPTSLQPGAPPAARAW 211

Query: 187 SGVTDCWACFA--EPWGRRTYVTWIALMVFVAP--TLGIAACQVLIFREIHASLVPGPSE 242
            G   C   FA    W  + Y  + A+  FVAP   LG+A   +L     H    P  + 
Sbjct: 212 PGERRCHGIFAPLPRWHLQVYAFYEAVAGFVAPVTVLGVACGHLLSVWWRHRPQAPA-AA 270

Query: 243 RPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWD--PEA 300
            P     GR   +P   A +  A  ++++M+L++ +++V C  P+F  +L AAW   P  
Sbjct: 271 APWSASPGR---APAPSA-LPRAKVQSLKMSLLLALLFVGCELPYFAARLAAAWSSGPAG 326

Query: 301 PLEG 304
             EG
Sbjct: 327 DWEG 330


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 65/268 (24%), Positives = 119/268 (44%), Gaps = 26/268 (9%)

Query: 46  IVFVAVALSNGLVLAALARRGRRGHWAPI-HVFIGHLCLADLAVALFQVLPQLAWKATDR 104
           IVFV   + N LV  A+    +  H   + + FI +L LAD+ V +  +   L    T+ 
Sbjct: 63  IVFVVALIGNVLVCVAV---WKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET 119

Query: 105 FRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAW 164
           +    +LC+ + YLQ V +  S   +  + LDR  AIC P++       A     +++ W
Sbjct: 120 WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRA--RNSIVIIW 177

Query: 165 AFSLLLSLPQLFIFAQRNV-EGGSGVTDCWACFAEPWG----RRTYVTWIALMVFVAPTL 219
             S ++ +PQ  +     V  G +  T  +    E WG     + Y     L+ ++AP  
Sbjct: 178 IVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLC 237

Query: 220 GIAACQVLIFREIHASLVPGPSE---------RPGGRRRGRRTGSPGEGAHVSAAV---- 266
            +    + IFR++    +PG S          +P  + RG    +    + V+A +    
Sbjct: 238 LMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIR 297

Query: 267 --AKTVRMTLVIVVVYVLCWAPFFLVQL 292
              KT RM +++++V+ +C+ P  ++ +
Sbjct: 298 ARRKTARMLMIVLLVFAICYLPISILNV 325


>gi|4502607 cholecystokinin A receptor [Homo sapiens]
          Length = 428

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 69/316 (21%), Positives = 129/316 (40%), Gaps = 51/316 (16%)

Query: 25  QERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLA 84
           Q RP     P +   ++ L S++F+   L N LV+  L R  R       ++F+  L ++
Sbjct: 32  QPRPSKEWQPAV---QILLYSLIFLLSVLGNTLVITVLIRNKRMR--TVTNIFLLSLAVS 86

Query: 85  DLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRP 144
           DL + LF +   L       F    A+C+   Y     +  S++ ++A++L+R+ AIC+P
Sbjct: 87  DLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKP 146

Query: 145 MLAYRHGSGAHWNRPVLVAWAFSLLLSLP-----QLFIFAQRNVEGGSGVTDCWACFAEP 199
           + +    + +H  + +   W  S  +  P      L  F + N         C       
Sbjct: 147 LQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNN---NQTANMCRFLLPND 203

Query: 200 WGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPG-- 257
             ++++ T++ L++F+ P + +     LI  E++  +    S++   + R   T S G  
Sbjct: 204 VMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKY 263

Query: 258 ---EGAHVS---------------------------------AAVAKTVRMTLVIVVVYV 281
              +G ++                                   A  + +RM +VIVV++ 
Sbjct: 264 EDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFF 323

Query: 282 LCWAPFFLVQLWAAWD 297
           LCW P F    W A+D
Sbjct: 324 LCWMPIFSANAWRAYD 339


>gi|20373179 G protein-coupled receptor 73 [Homo sapiens]
          Length = 393

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 71/269 (26%), Positives = 125/269 (46%), Gaps = 55/269 (20%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVAL--------FQ 92
           +AL+ I+ V   + N + +AAL R  +  +    ++ I +L ++D  VA+        + 
Sbjct: 67  MALVGIMLVC-GIGNFIFIAALVRYKKLRNLT--NLLIANLAISDFLVAIVCCPFEMDYY 123

Query: 93  VLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAI---CRPMLAYR 149
           V+ QL+W+          LC +V YL+ V +Y S+  +LA+ +DR+ AI    RP +  +
Sbjct: 124 VVRQLSWEHGH------VLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQ 177

Query: 150 HGSGAHWNRPVLVAWAFSLLLSLPQLF---------IFAQRNVEGGSGVTDCWACFAEPW 200
             +G      + + W  S+L+++P  +         + +Q  +  G      W    + +
Sbjct: 178 TATGL-----IALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCG----QIWPVDQQLY 228

Query: 201 GRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPG-PSERPGGRRRGRRTGSPGEG 259
             ++Y  +I  + FV P + +  C   I RE+    VPG  +E+   R R RR       
Sbjct: 229 -YKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRR------- 280

Query: 260 AHVSAAVAKTVRMTLVIVVVYVLCWAPFF 288
                   KTV + + I+  YVLCWAPF+
Sbjct: 281 --------KTVLVLMCILTAYVLCWAPFY 301


>gi|21426829 prokineticin receptor 2 [Homo sapiens]
          Length = 384

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 71/263 (26%), Positives = 122/263 (46%), Gaps = 43/263 (16%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVAL--------FQ 92
           +AL  I+ V   + N + +AAL R  +  +    ++ I +L ++D  VA+        + 
Sbjct: 58  IALAGIMLVC-GIGNFVFIAALTRYKKLRNLT--NLLIANLAISDFLVAIICCPFEMDYY 114

Query: 93  VLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGS 152
           V+ QL+W+          LC +V YL+ V +Y S+  +LA+ +DR+ AI  P+    +  
Sbjct: 115 VVRQLSWEHGH------VLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQ 168

Query: 153 GAHWNRPVLVAWAFSLLLSLPQLFIFAQRNV------EGGSGVTDCWACFAEPWGRRTYV 206
            A +   + + W  S+L+++P  + FA   V      +        W    + +  ++Y 
Sbjct: 169 TASF--LIALVWMVSILIAIPSAY-FATETVLFIVKSQEKIFCGQIWPVDQQLY-YKSYF 224

Query: 207 TWIALMVFVAPTLGIAACQVLIFREIHASLVPG-PSERPGGRRRGRRTGSPGEGAHVSAA 265
            +I  + FV P + +  C   I RE+    VPG  +E+   R R RR             
Sbjct: 225 LFIFGVEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRR------------- 271

Query: 266 VAKTVRMTLVIVVVYVLCWAPFF 288
             KTV + + I+  YVLCWAPF+
Sbjct: 272 --KTVLVLMCILTAYVLCWAPFY 292


>gi|218563730 chemokine (C-X-C motif) receptor 3 isoform B [Homo
           sapiens]
          Length = 415

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 34/252 (13%)

Query: 42  ALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKA 101
           AL S++F+   L NG V A L    RR   +    F+ HL +AD  + L   LP  A  A
Sbjct: 105 ALYSLLFLLGLLGNGAVAAVLL--SRRTALSSTDTFLLHLAVADTLLVL--TLPLWAVDA 160

Query: 102 TDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVL 161
             ++     LC+    L  +  YA + ++  ++ DR+  I      YR G  A      L
Sbjct: 161 AVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCL 220

Query: 162 VAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMV-FVAPTLG 220
             W   LL +LP  FIF   + +     T C   F  P   RT +  + L+  F+ P L 
Sbjct: 221 AVWGLCLLFALPD-FIFLSAHHDERLNATHCQYNF--PQVGRTALRVLQLVAGFLLPLLV 277

Query: 221 IAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVY 280
           +A C   I   +  S             RG+R               + +R+ +V+VV +
Sbjct: 278 MAYCYAHILAVLLVS-------------RGQRR-------------LRAMRLVVVVVVAF 311

Query: 281 VLCWAPFFLVQL 292
            LCW P+ LV L
Sbjct: 312 ALCWTPYHLVVL 323


>gi|4504099 chemokine (C-X-C motif) receptor 3 isoform A [Homo
           sapiens]
          Length = 368

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 71/252 (28%), Positives = 105/252 (41%), Gaps = 34/252 (13%)

Query: 42  ALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKA 101
           AL S++F+   L NG V A L    RR   +    F+ HL +AD  + L   LP  A  A
Sbjct: 58  ALYSLLFLLGLLGNGAVAAVLL--SRRTALSSTDTFLLHLAVADTLLVL--TLPLWAVDA 113

Query: 102 TDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVL 161
             ++     LC+    L  +  YA + ++  ++ DR+  I      YR G  A      L
Sbjct: 114 AVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCL 173

Query: 162 VAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMV-FVAPTLG 220
             W   LL +LP  FIF   + +     T C   F  P   RT +  + L+  F+ P L 
Sbjct: 174 AVWGLCLLFALPD-FIFLSAHHDERLNATHCQYNF--PQVGRTALRVLQLVAGFLLPLLV 230

Query: 221 IAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVY 280
           +A C   I   +  S             RG+R               + +R+ +V+VV +
Sbjct: 231 MAYCYAHILAVLLVS-------------RGQRR-------------LRAMRLVVVVVVAF 264

Query: 281 VLCWAPFFLVQL 292
            LCW P+ LV L
Sbjct: 265 ALCWTPYHLVVL 276


>gi|9506745 urotensin 2 receptor [Homo sapiens]
          Length = 389

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 85/305 (27%), Positives = 135/305 (44%), Gaps = 35/305 (11%)

Query: 3   MASTTSAVPGHPSLPSLPSNSSQERPLD--TRDPLLARAELA-LLSIVFVAVALSNGLVL 59
           +A+T S+VP  P  P+   NSS   P +  + + L+A   +  LLS + V   + N   L
Sbjct: 14  LAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSAMGVVGVVGNAYTL 73

Query: 60  AALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQ 119
               R  R    A ++V++ +L LADL + L  +   +A   T  +   D  CR +  L 
Sbjct: 74  VVTCRSLRAV--ASMYVYVVNLALADL-LYLLSIPFIVATYVTKEWHFGDVGCRVLFGLD 130

Query: 120 MVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFA 179
            + M+AS + +  M+ +R+ A+ RP+   +   G +     L  W  +LLL+LP   + A
Sbjct: 131 FLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKG-YRKLLALGTWLLALLLTLP--VMLA 187

Query: 180 QRNVEGG--SGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLV 237
            R V  G  S     W     P   R Y+T +       P L I      + R    S  
Sbjct: 188 MRLVRRGPKSLCLPAWG----PRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRRS-- 241

Query: 238 PGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWD 297
                +    +R RR G            A+ +R+ L IV+++  C+ PF+L QL A + 
Sbjct: 242 -----QRASFKRARRPG------------ARALRLVLGIVLLFWACFLPFWLWQLLAQYH 284

Query: 298 PEAPL 302
            +APL
Sbjct: 285 -QAPL 288


>gi|4503905 galanin receptor 2 [Homo sapiens]
          Length = 387

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 69/260 (26%), Positives = 116/260 (44%), Gaps = 24/260 (9%)

Query: 43  LLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKAT 102
           L +++F+   + N LVLA L R G+    +  ++FI +L +ADL   L  V  Q      
Sbjct: 31  LFALIFLVGTVGNTLVLAVLLRGGQAV--STTNLFILNLGVADLCFILCCVPFQATIYTL 88

Query: 103 DRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLV 162
           D +     LC+AV +L  + M+ASS+ + A++LDR+ AI  P+ +    +  +    + +
Sbjct: 89  DGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGL 148

Query: 163 AWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIA 222
            W  SLL S P L  + Q  +   + +T C   ++ P  RR       +  ++ P L + 
Sbjct: 149 IWGLSLLFSGPYLSYYRQSQL---ANLTVCHPAWSAP-RRRAMDICTFVFSYLLPVLVLG 204

Query: 223 ACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVL 282
                  R +  ++   P     G RR +R               K  RM L++  ++ L
Sbjct: 205 LTYARTLRYLWRAV--DPVAAGSGARRAKR---------------KVTRMILIVAALFCL 247

Query: 283 CWAPFFLVQLWAAWDPEAPL 302
           CW P   + L   W  + PL
Sbjct: 248 CWMPHHALIL-CVWFGQFPL 266


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 68/257 (26%), Positives = 111/257 (43%), Gaps = 31/257 (12%)

Query: 43  LLSIVFVAVAL----SNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLA 98
           L+S ++  V L     N +V+  + R  +       +++I +L +AD  + L   +P L 
Sbjct: 60  LISFIYSVVCLVGLCGNSMVIYVILRYAKMK--TATNIYILNLAIADELLMLS--VPFLV 115

Query: 99  WKATDRFRGPDAL-CRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWN 157
                R     AL CR V  +  V M+ S Y +  +++DR+ A+  P+ A R+       
Sbjct: 116 TSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAK 175

Query: 158 RPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRT--YVTWIALMVFV 215
              L  W  SLL+ LP   +   R      G   C     EP  R    +V +  LM F+
Sbjct: 176 VVNLGVWVLSLLVILP--IVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFL 233

Query: 216 APTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLV 275
            P   I  C VLI  ++    +    ++   R+R  R               K   M ++
Sbjct: 234 LPVGAICLCYVLIIAKMRMVALKAGWQQ---RKRSER---------------KITLMVMM 275

Query: 276 IVVVYVLCWAPFFLVQL 292
           +V+V+V+CW PF++VQL
Sbjct: 276 VVMVFVICWMPFYVVQL 292


>gi|31881792 leukotriene B4 receptor [Homo sapiens]
          Length = 352

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 75/266 (28%), Positives = 120/266 (45%), Gaps = 40/266 (15%)

Query: 34  PLLARAELALLSIVFVAVALSNGL------VLAALARRGRRGHWAPIHVFIGHLCLADLA 87
           P L    ++LL+I+ ++VAL+ GL      V + L R  +R   A   + + +L LADLA
Sbjct: 10  PSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTA---LMVLNLALADLA 66

Query: 88  VALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLA 147
           V L      L + A   +    A CR   Y+  V MYAS  +I AM+LDR  A+ RP ++
Sbjct: 67  VLLTAPF-FLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVS 125

Query: 148 YRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRN-VEGGSGVTDCWACFAEPWGRRTYV 206
            +  + A   R +   W  S LL+ P   + A R  V   + ++ C+  +     R  ++
Sbjct: 126 QKLRTKAMARRVLAGIWVLSFLLATP---VLAYRTVVPWKTNMSLCFPRYPSEGHRAFHL 182

Query: 207 TWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAV 266
            + A+  F+ P L + A    I R + A             RR RRTG            
Sbjct: 183 IFEAVTGFLLPFLAVVASYSDIGRRLQARRF----------RRSRRTG------------ 220

Query: 267 AKTVRMTLVIVVVYVLCWAPFFLVQL 292
               R+ ++I++ +   W P+ +V L
Sbjct: 221 ----RLVVLIILTFAAFWLPYHVVNL 242


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 71/276 (25%), Positives = 121/276 (43%), Gaps = 30/276 (10%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPI-HVFIGHLCLADLAVALFQVLPQLAW 99
           +A    VFV   + N LV  A+    R  H   + + FI +L LAD+ V    +   L  
Sbjct: 50  IAAYVAVFVVALVGNTLVCLAV---WRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLV 106

Query: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
             T+ +    ALC+ + YLQ V +  +   +  + LDR  AIC P+L       A  +  
Sbjct: 107 DITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGS-- 164

Query: 160 VLVAWAFSLLLSLPQLFIFAQRNV-EGGSGVTDCWACFAEPWG----RRTYVTWIALMVF 214
           +L  WA SL + +PQ  +    +V    +  T  ++   E W      + Y +   ++ +
Sbjct: 165 ILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTY 224

Query: 215 VAPTLGIAACQVLIFREIHASLVPG-----------PSERPGGRRRGRRTGSPGEGAHVS 263
           +AP   +A     IFR++    +PG           PS++ G   +G  +G P   A   
Sbjct: 225 LAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQG-LSGEPQPRARAF 283

Query: 264 AAVA-------KTVRMTLVIVVVYVLCWAPFFLVQL 292
            A         KT +M +V+++V+ LC+ P  ++ +
Sbjct: 284 LAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNV 319


>gi|221218998 leukotriene B4 receptor [Homo sapiens]
          Length = 352

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 75/266 (28%), Positives = 120/266 (45%), Gaps = 40/266 (15%)

Query: 34  PLLARAELALLSIVFVAVALSNGL------VLAALARRGRRGHWAPIHVFIGHLCLADLA 87
           P L    ++LL+I+ ++VAL+ GL      V + L R  +R   A   + + +L LADLA
Sbjct: 10  PSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTA---LMVLNLALADLA 66

Query: 88  VALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLA 147
           V L      L + A   +    A CR   Y+  V MYAS  +I AM+LDR  A+ RP ++
Sbjct: 67  VLLTAPF-FLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVS 125

Query: 148 YRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRN-VEGGSGVTDCWACFAEPWGRRTYV 206
            +  + A   R +   W  S LL+ P   + A R  V   + ++ C+  +     R  ++
Sbjct: 126 QKLRTKAMARRVLAGIWVLSFLLATP---VLAYRTVVPWKTNMSLCFPRYPSEGHRAFHL 182

Query: 207 TWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAV 266
            + A+  F+ P L + A    I R + A             RR RRTG            
Sbjct: 183 IFEAVTGFLLPFLAVVASYSDIGRRLQARRF----------RRSRRTG------------ 220

Query: 267 AKTVRMTLVIVVVYVLCWAPFFLVQL 292
               R+ ++I++ +   W P+ +V L
Sbjct: 221 ----RLVVLIILTFAAFWLPYHVVNL 242


>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
          Length = 372

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 80/302 (26%), Positives = 127/302 (42%), Gaps = 34/302 (11%)

Query: 2   LMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPL-LARAELALLSIVFVAVALSNGLVLA 60
           L A+ + A P   + PS  +N+S      +   L LA A  AL S V     L N LV+ 
Sbjct: 15  LFANASDAYPS--ACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMF 72

Query: 61  ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM 120
            + R  +      I++F  +L LAD A+A   +  Q A    + +   + LC+AV  +  
Sbjct: 73  GIVRYTKMKTATNIYIF--NLALAD-ALATSTLPFQSAKYLMETWPFGELLCKAVLSIDY 129

Query: 121 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ 180
             M+ S + +  M++DR+ A+C P+ A    + A      +  W  +  + +P + +   
Sbjct: 130 YNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVT 189

Query: 181 RNVEGGSGVTDCWACFAEP---WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASL 236
           R  +   G   C   F  P   W   T +  + L  FV P L I  C  +++ R     L
Sbjct: 190 RPRD---GAVVCMLQFPSPSWYWDTVTKIC-VFLFAFVVPILIITVCYGLMLLRLRSVRL 245

Query: 237 VPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFL-VQLWAA 295
           + G  E+    RR                     RM LV+V  +V+CWAP  + V +W  
Sbjct: 246 LSGSKEKDRSLRR-------------------ITRMVLVVVGAFVVCWAPIHIFVIVWTL 286

Query: 296 WD 297
            D
Sbjct: 287 VD 288


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 38/254 (14%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWK 100
           + L   V V   L N LV+  + R  +      I++F  +L LAD  V L      L ++
Sbjct: 55  VGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIF--NLALADTLVLL-----TLPFQ 107

Query: 101 ATDRFRG----PDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHW 156
            TD   G     +ALC+ V  +    M+ S++ + AM++DR+ AIC P+ A    + +  
Sbjct: 108 GTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKA 167

Query: 157 NRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEP---WGRRTYVTWIALMV 213
               +  WA + ++ +P + I     VE      +C      P   WG   +   I L  
Sbjct: 168 QAVNVAIWALASVVGVP-VAIMGSAQVEDEE--IECLVEIPTPQDYWG-PVFAICIFLFS 223

Query: 214 FVAPTLGIAACQVLIFREIH-ASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRM 272
           F+ P L I+ C  L+ R +    L+ G  E+    RR                     R+
Sbjct: 224 FIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRR-------------------ITRL 264

Query: 273 TLVIVVVYVLCWAP 286
            LV+V V+V CW P
Sbjct: 265 VLVVVAVFVGCWTP 278


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 38/254 (14%)

Query: 41  LALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWK 100
           + L   V V   L N LV+  + R  +      I++F  +L LAD  V L      L ++
Sbjct: 55  VGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIF--NLALADTLVLL-----TLPFQ 107

Query: 101 ATDRFRG----PDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHW 156
            TD   G     +ALC+ V  +    M+ S++ + AM++DR+ AIC P+ A    + +  
Sbjct: 108 GTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKA 167

Query: 157 NRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEP---WGRRTYVTWIALMV 213
               +  WA + ++ +P + I     VE      +C      P   WG   +   I L  
Sbjct: 168 QAVNVAIWALASVVGVP-VAIMGSAQVEDEE--IECLVEIPTPQDYWG-PVFAICIFLFS 223

Query: 214 FVAPTLGIAACQVLIFREIH-ASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRM 272
           F+ P L I+ C  L+ R +    L+ G  E+    RR                     R+
Sbjct: 224 FIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRR-------------------ITRL 264

Query: 273 TLVIVVVYVLCWAP 286
            LV+V V+V CW P
Sbjct: 265 VLVVVAVFVGCWTP 278


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 66/286 (23%), Positives = 113/286 (39%), Gaps = 36/286 (12%)

Query: 11  PGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGH 70
           P  P+   L    S   P  +   + A   +AL SIV V     N LV+  + R  +   
Sbjct: 137 PCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKT 196

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGP----DALCRAVKYLQMVGMYAS 126
              I++F  +L LAD           L +++ +   G       LC+ V  +    M+ S
Sbjct: 197 ATNIYIF--NLALADALAT-----STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTS 249

Query: 127 SYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGG 186
            + +  M++DR+ A+C P+ A    +  +     +  W  S  + LP +F+   +  +G 
Sbjct: 250 IFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS 309

Query: 187 SGVTDCWACFAEP--WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASLVPGPSER 243
               DC   F+ P  +        + +  F+ P L I  C  ++I R     ++ G  E+
Sbjct: 310 ---IDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEK 366

Query: 244 PGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFL 289
               RR                     RM LV+V V+++CW P  +
Sbjct: 367 DRNLRR-------------------ITRMVLVVVAVFIVCWTPIHI 393


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 66/286 (23%), Positives = 113/286 (39%), Gaps = 36/286 (12%)

Query: 11  PGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGH 70
           P  P+   L    S   P  +   + A   +AL SIV V     N LV+  + R  +   
Sbjct: 44  PCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKT 103

Query: 71  WAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGP----DALCRAVKYLQMVGMYAS 126
              I++F  +L LAD           L +++ +   G       LC+ V  +    M+ S
Sbjct: 104 ATNIYIF--NLALADALAT-----STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTS 156

Query: 127 SYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGG 186
            + +  M++DR+ A+C P+ A    +  +     +  W  S  + LP +F+   +  +G 
Sbjct: 157 IFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGS 216

Query: 187 SGVTDCWACFAEP--WGRRTYVTWIALMVFVAPTLGIAACQ-VLIFREIHASLVPGPSER 243
               DC   F+ P  +        + +  F+ P L I  C  ++I R     ++ G  E+
Sbjct: 217 ---IDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEK 273

Query: 244 PGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFL 289
               RR                     RM LV+V V+++CW P  +
Sbjct: 274 DRNLRR-------------------ITRMVLVVVAVFIVCWTPIHI 300


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.138    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,622,682
Number of Sequences: 37866
Number of extensions: 547108
Number of successful extensions: 3675
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 324
Number of HSP's that attempted gapping in prelim test: 3159
Number of HSP's gapped (non-prelim): 622
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.