Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 225690502

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225690502 junctophilin 4 [Homo sapiens]
         (628 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225690502 junctophilin 4 [Homo sapiens]                           1294   0.0  
gi|225690500 junctophilin 4 [Homo sapiens]                           1294   0.0  
gi|21704283 junctophilin 3 [Homo sapiens]                             460   e-129
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]                   450   e-126
gi|21735575 junctophilin 1 [Homo sapiens]                             437   e-122
gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]                   189   7e-48
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]              73   7e-13
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]            69   1e-11
gi|157502187 radial spoke head 10 homolog B [Homo sapiens]             69   1e-11
gi|18254456 testis-specific gene A2 [Homo sapiens]                     65   2e-10
gi|50355990 MORN repeat containing 3 [Homo sapiens]                    63   9e-10
gi|40316935 alsin isoform 1 [Homo sapiens]                             61   3e-09
gi|13376267 MORN repeat containing 1 [Homo sapiens]                    61   4e-09
gi|149999376 MORN repeat containing 4 [Homo sapiens]                   56   9e-08
gi|30520314 MORN repeat containing 4 [Homo sapiens]                    56   9e-08
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    53   1e-06
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]             51   4e-06
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       49   1e-05
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       49   1e-05
gi|57864582 hornerin [Homo sapiens]                                    49   2e-05
gi|109637771 calpastatin isoform l [Homo sapiens]                      47   5e-05
gi|109637769 calpastatin isoform k [Homo sapiens]                      47   5e-05
gi|109637767 calpastatin isoform j [Homo sapiens]                      47   5e-05
gi|109637765 calpastatin isoform i [Homo sapiens]                      47   5e-05
gi|109637763 calpastatin isoform h [Homo sapiens]                      47   5e-05
gi|109637761 calpastatin isoform g [Homo sapiens]                      47   5e-05
gi|109637759 calpastatin isoform f [Homo sapiens]                      47   5e-05
gi|109637757 calpastatin isoform e [Homo sapiens]                      47   5e-05
gi|27765085 calpastatin isoform b [Homo sapiens]                       47   5e-05
gi|109637753 calpastatin isoform a [Homo sapiens]                      47   5e-05

>gi|225690502 junctophilin 4 [Homo sapiens]
          Length = 628

 Score = 1294 bits (3348), Expect = 0.0
 Identities = 628/628 (100%), Positives = 628/628 (100%)

Query: 1   MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS 60
           MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS
Sbjct: 1   MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS 60

Query: 61  YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT 120
           YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT
Sbjct: 61  YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT 120

Query: 121 ETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLP 180
           ETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLP
Sbjct: 121 ETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLP 180

Query: 181 GDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSK 240
           GDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSK
Sbjct: 181 GDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSK 240

Query: 241 RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRS 300
           RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRS
Sbjct: 241 RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRS 300

Query: 301 NGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKV 360
           NGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKV
Sbjct: 301 NGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKV 360

Query: 361 DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPML 420
           DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPML
Sbjct: 361 DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPML 420

Query: 421 EAPGRRPRQDSEGSDTEPLDEDSPGVYENGLTPSEGSPELPSSPASSRQPWRPPACRSPL 480
           EAPGRRPRQDSEGSDTEPLDEDSPGVYENGLTPSEGSPELPSSPASSRQPWRPPACRSPL
Sbjct: 421 EAPGRRPRQDSEGSDTEPLDEDSPGVYENGLTPSEGSPELPSSPASSRQPWRPPACRSPL 480

Query: 481 PPGGDQGPFSSPKAWPEEWGGAGAQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSG 540
           PPGGDQGPFSSPKAWPEEWGGAGAQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSG
Sbjct: 481 PPGGDQGPFSSPKAWPEEWGGAGAQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSG 540

Query: 541 SLREEEGEDEEPLPPLRAPAGTEPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQ 600
           SLREEEGEDEEPLPPLRAPAGTEPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQ
Sbjct: 541 SLREEEGEDEEPLPPLRAPAGTEPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQ 600

Query: 601 PGAANPLVVGAVALLDLSLAFLFSQLLT 628
           PGAANPLVVGAVALLDLSLAFLFSQLLT
Sbjct: 601 PGAANPLVVGAVALLDLSLAFLFSQLLT 628


>gi|225690500 junctophilin 4 [Homo sapiens]
          Length = 628

 Score = 1294 bits (3348), Expect = 0.0
 Identities = 628/628 (100%), Positives = 628/628 (100%)

Query: 1   MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS 60
           MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS
Sbjct: 1   MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS 60

Query: 61  YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT 120
           YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT
Sbjct: 61  YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT 120

Query: 121 ETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLP 180
           ETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLP
Sbjct: 121 ETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLP 180

Query: 181 GDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSK 240
           GDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSK
Sbjct: 181 GDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSK 240

Query: 241 RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRS 300
           RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRS
Sbjct: 241 RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRS 300

Query: 301 NGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKV 360
           NGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKV
Sbjct: 301 NGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKVKEKV 360

Query: 361 DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPML 420
           DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPML
Sbjct: 361 DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDLQPML 420

Query: 421 EAPGRRPRQDSEGSDTEPLDEDSPGVYENGLTPSEGSPELPSSPASSRQPWRPPACRSPL 480
           EAPGRRPRQDSEGSDTEPLDEDSPGVYENGLTPSEGSPELPSSPASSRQPWRPPACRSPL
Sbjct: 421 EAPGRRPRQDSEGSDTEPLDEDSPGVYENGLTPSEGSPELPSSPASSRQPWRPPACRSPL 480

Query: 481 PPGGDQGPFSSPKAWPEEWGGAGAQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSG 540
           PPGGDQGPFSSPKAWPEEWGGAGAQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSG
Sbjct: 481 PPGGDQGPFSSPKAWPEEWGGAGAQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSG 540

Query: 541 SLREEEGEDEEPLPPLRAPAGTEPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQ 600
           SLREEEGEDEEPLPPLRAPAGTEPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQ
Sbjct: 541 SLREEEGEDEEPLPPLRAPAGTEPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQ 600

Query: 601 PGAANPLVVGAVALLDLSLAFLFSQLLT 628
           PGAANPLVVGAVALLDLSLAFLFSQLLT
Sbjct: 601 PGAANPLVVGAVALLDLSLAFLFSQLLT 628


>gi|21704283 junctophilin 3 [Homo sapiens]
          Length = 748

 Score =  460 bits (1183), Expect = e-129
 Identities = 269/532 (50%), Positives = 341/532 (64%), Gaps = 50/532 (9%)

Query: 1   MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHS 60
           MS GG+F+FDDGG Y GGWE G+AHG+GVCTGP  QGEY+G W+HGFE LGV+T P G++
Sbjct: 1   MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT 60

Query: 61  YQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESV-SGLRYAGLWKDGFQDGYG 119
           YQG W QGKR G+G+E K +W Y+GEW  G KGR GV E   +G +Y G W +G QDGYG
Sbjct: 61  YQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYG 120

Query: 120 TETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPP--TPPPPL 177
           TETYSDGGTYQGQW  G R GYGVRQSVPY  AA++RSP RTS++S  S+    T   P 
Sbjct: 121 TETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPD 180

Query: 178 PLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSG--LRAGGRRS 235
             P    GSPA  SRGGFVL    D++   S+K+     G FRRS LLSG  LR    +S
Sbjct: 181 ASPA-VAGSPAV-SRGGFVLVAHSDSEILKSKKK-----GLFRRS-LLSGLKLRKSESKS 232

Query: 236 SLG---SKRGSLRSEVS-SEVGSTGPP-GSEASGPPAAAPPALIE----GSATEVYAGEW 286
           SL    SK+ S RSE   S V ST     S  S   A A  A+IE     + TE Y GEW
Sbjct: 233 SLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEW 292

Query: 287 RADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSL 346
           + D+RSGFGVSQRS+GL+YEGEW  NRRHGYG  T PDG++EEGKYK+N LV GG+ ++L
Sbjct: 293 KNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILV-GGKRKNL 351

Query: 347 LPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAA 406
           +P  LR  K++EKVDRAVE A RA + A+Q+ EIAA+R + +  KA AA + A+KA E A
Sbjct: 352 IP--LRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEA 409

Query: 407 RMAKLIAQDLQPMLE-----APGRRPRQDSEGSDTE------PLDEDSPGVYENGLTPSE 455
           R+A++ A++  P  +        +RP++ +   D E      PL ++SP +Y  G TPS+
Sbjct: 410 RIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQESPELYRKGTTPSD 469

Query: 456 GSPE------LPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGG 501
            +P+       P+SPA++  P   PA R+ +        FS   +  EE GG
Sbjct: 470 LTPDDSPLQSFPTSPAATPPP--APAARNKV------AHFSRQVSVDEERGG 513


>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
          Length = 696

 Score =  450 bits (1157), Expect = e-126
 Identities = 293/704 (41%), Positives = 377/704 (53%), Gaps = 89/704 (12%)

Query: 4   GGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQG 63
           GG+FDFDDGG Y GGWE G+AHG+G+CTGP  QGEYSG W  GFE  GV+T P G++++G
Sbjct: 3   GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEG 62

Query: 64  HWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWE-SVSGLRYAGLWKDGFQDGYGTET 122
           +W QGKR GLG+E K RW Y+GEW  G KGR G+ + S SG +Y G W +G QDGYGTET
Sbjct: 63  YWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTET 122

Query: 123 YSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLD---SGHSDPPTPPPPLPL 179
           Y+DGGTYQGQ+  G RHGYGVRQSVPY  A ++RSP RTSL    S HS+    P     
Sbjct: 123 YADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPAS 182

Query: 180 PGDEGGSPASGS--RGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSL 237
           P  +G +  S +  RGGF L+   +A+ A+   R P  GG F+R  LL  LR    R+S+
Sbjct: 183 PASDGPALPSPAIPRGGFALSLLANAEAAA---RAPKGGGLFQRGALLGKLRRAESRTSV 239

Query: 238 GSKRGS---LRSEVS---SEVGSTGPPGSEASGPPAAAP-PALIEGSATEVYAGEWRADR 290
           GS+R     L+S++S   S+  ST   G  A G   AAP  A I+ + TE Y GEW+ D+
Sbjct: 240 GSQRSRVSFLKSDLSSGASDAASTASLGEAAEGADEAAPFEADIDATTTETYMGEWKNDK 299

Query: 291 RSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLA 350
           RSGFGVS+RS+GLRYEGEWL N RHGYG TT PDG REEGKY+ N LV   + R    L 
Sbjct: 300 RSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRRM---LQ 356

Query: 351 LRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAK 410
           L+  KV++KV+ +VEGA+RA + ARQ+ EIAA+R + A  KA AA   A  A + + +A+
Sbjct: 357 LKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIAR 416

Query: 411 LIAQDLQPMLEAPG-----RRPRQDSEGSDTEPLDEDSPGVYENGL-TPSEGSPELPSSP 464
            +A++L P    PG     RR  Q+   +    L+    G    GL  P   SP+L    
Sbjct: 417 TLARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRGAGAAGLPQPPRESPQLHERE 476

Query: 465 ASSRQPWRP-PACRSPLP----PGGDQGPFSSPKAWPEEWGGAGAQ-------------- 505
               +   P PA   P P    PG  +    SP AW  E  G G++              
Sbjct: 477 TPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAGRRSPA 536

Query: 506 --AEELAGYEA---------EDEAGM-QG------------PGPRDGSPLLGGCSDSSGS 541
             A E    EA         E E  + QG            P P +  P      + SGS
Sbjct: 537 RPATERMAIEALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPE----PEVSGS 592

Query: 542 LREEEGEDEEPL---------PPLRAPAGTEPEPIAMLVLRGSSSRGPDAGCLTEELGEP 592
                     PL         P    PA  EP+PI       + +R  +A  LT+   + 
Sbjct: 593 ESAPSSPATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKARKTEARGLTKAGAKK 652

Query: 593 AATERPAQPGAA--------NPLVVGAVALLDLSLAFLFSQLLT 628
            A +  A    A        N +++  V LL++ LA LF  LLT
Sbjct: 653 KARKEAALAAEAEVEVEEVPNTILICMVILLNIGLAILFVHLLT 696


>gi|21735575 junctophilin 1 [Homo sapiens]
          Length = 661

 Score =  437 bits (1124), Expect = e-122
 Identities = 244/490 (49%), Positives = 303/490 (61%), Gaps = 33/490 (6%)

Query: 4   GGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQG 63
           GG+FDFDDGG Y GGWE G+AHG+G+CTGP  QGEYSG W+HGFE +G +T P G++YQG
Sbjct: 3   GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQG 62

Query: 64  HWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESV-SGLRYAGLWKDGFQDGYGTET 122
           +W QGKR GLGVE K +W YRGEW  G KGR GV +S+ +  RY G W +G QDGYG ET
Sbjct: 63  YWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVET 122

Query: 123 YSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGD 182
           Y DGGTYQGQW  G RHGYGVRQSVPY  A ++RSP RTSL S  S+       L     
Sbjct: 123 YGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSV-LHDAAA 181

Query: 183 EGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSG--LRAGGRRSSLGSK 240
              SPA G+RGGFVL    DA+ A  +K     GG FRR  LL    LR    +SS+ SK
Sbjct: 182 AADSPA-GTRGGFVLNFHADAELAGKKK-----GGLFRRGSLLGSMKLRKSESKSSISSK 235

Query: 241 RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIE----GSATEVYAGEWRADRRSGFGV 296
           R S+RS+ +    S+    S  S          +E     + TE Y GEW+ D+R+GFGV
Sbjct: 236 RSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGV 295

Query: 297 SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKV 356
           S+RSNG++YEGEW  N+RHGYG T  PDGS+EEGKYK N LV G R + L+P+  R  K 
Sbjct: 296 SERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIR-KQLIPI--RHTKT 352

Query: 357 KEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDL 416
           +EKVDRA+EGA+RA + AR + EIA +R A A  KA AA   A  A +   +A+ +A++L
Sbjct: 353 REKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVAREL 412

Query: 417 QPMLEAPGRR--PRQDSEGSDTE-----------PLDEDSPGVYENGLTP---SEGSPEL 460
            P    PG     ++  EG D +           P  ++SP  Y  G TP    E SP+ 
Sbjct: 413 SPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKH 472

Query: 461 PSSPASSRQP 470
             SPASS +P
Sbjct: 473 SHSPASSPKP 482


>gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]
          Length = 129

 Score =  189 bits (480), Expect = 7e-48
 Identities = 79/125 (63%), Positives = 96/125 (76%), Gaps = 1/125 (0%)

Query: 4   GGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQG 63
           GG+FDFDDGG Y GGWE G+AHG+G+CTGP  QGEYSG W  GFE  GV+T P G++++G
Sbjct: 3   GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEG 62

Query: 64  HWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWE-SVSGLRYAGLWKDGFQDGYGTET 122
           +W QGKR GLG+E K RW Y+GEW  G KGR G+ + S SG +Y G W +G QDGYGTET
Sbjct: 63  YWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTET 122

Query: 123 YSDGG 127
           Y+DGG
Sbjct: 123 YADGG 127



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 22/93 (23%)

Query: 51  GVFTGPGGHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLW 110
           G F    G +Y G W+ GK  G G+              G KG+           Y+G W
Sbjct: 4   GRFDFDDGGAYCGGWEGGKAHGHGL------------CTGPKGQG---------EYSGSW 42

Query: 111 KDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
             GF+   G  T+  G T++G W  GKRHG G+
Sbjct: 43  NFGFEVA-GVYTWPSGNTFEGYWSQGKRHGLGI 74



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)

Query: 274 IEGSATEVYAGEWRADRRSGFGVSQRSN-GLRYEGEWLGNRRHGYGRTTRPDG 325
           IE     +Y GEW    +  +G+ Q S+ G +YEG W    + GYG  T  DG
Sbjct: 74  IETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADG 126


>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
          Length = 953

 Score = 73.2 bits (178), Expect = 7e-13
 Identities = 52/143 (36%), Positives = 66/143 (46%), Gaps = 17/143 (11%)

Query: 15  YVGGWEAGRAHGYGVCTGPGAQ---GEYSGCWAHGFESLGVFTGPGGHS-----YQGHWQ 66
           Y G W  GR HG G    P  +   G +     HGF   G+   P         Y+ HW+
Sbjct: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGF---GIRLLPQASEDKFDCYKCHWR 414

Query: 67  QGKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWES----VSGLRYAGLWKDGFQDGYGTE 121
           +G   G G+ E  +   Y+G +  GL+   GV ES        RY G W+ G + GYG E
Sbjct: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474

Query: 122 TYSD-GGTYQGQWQAGKRHGYGV 143
              D G  Y G WQAG+RHG GV
Sbjct: 475 EDGDRGERYIGMWQAGQRHGPGV 497



 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 46/150 (30%), Positives = 66/150 (44%), Gaps = 11/150 (7%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGC----WAHGFE-SLGVFTGPGGH 59
           G   + DG  +VG +  G  HG+G+   P A  +   C    W  G     G+       
Sbjct: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430

Query: 60  SYQGHWQQGKREGLGV-----ERKSRWTYRGEWLGGLKGRSGVWESVS-GLRYAGLWKDG 113
            Y+G++Q+G R G GV     +    + Y G W  G +   G+ E    G RY G+W+ G
Sbjct: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490

Query: 114 FQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
            + G G      G  YQG +QA K  G G+
Sbjct: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 39/128 (30%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 10  DDGGCYVGGWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFT-GPGGHSYQGHW 65
           D   CY   W  G   GYG+C   T    +G +     HGF  L      P    Y GHW
Sbjct: 404 DKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHW 463

Query: 66  QQGKREGLGVERKSRW--TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETY 123
           ++G+R G G+E        Y G W  G +   GV  + +G+ Y G ++     G G    
Sbjct: 464 ERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLS 523

Query: 124 SDGGTYQG 131
            D   Y+G
Sbjct: 524 EDDSLYEG 531



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%)

Query: 36  QGEYSGCWAHGF-ESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWT------YRGEWL 88
           Q  Y G W  G     G    P G ++ G++ QG   G G+    + +      Y+  W 
Sbjct: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414

Query: 89  GGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGT----YQGQWQAGKRHGYGVR 144
            G     G+ E  +   Y G +++G + G+G             Y G W+ G+R GYG+ 
Sbjct: 415 EGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIE 474

Query: 145 Q 145
           +
Sbjct: 475 E 475



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%)

Query: 282 YAGEWRADRRSGFGVSQRSN-GLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
           Y G W   +RSG+G+ +  + G RY G W   +RHG G      G   +G ++ ++ V  
Sbjct: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518

Query: 341 G 341
           G
Sbjct: 519 G 519



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 24/61 (39%), Positives = 28/61 (45%), Gaps = 6/61 (9%)

Query: 273 LIEGSATEVYAGEWRADRRSGFGV----SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSRE 328
           + E S  EVY G ++   R GFGV     Q     RY G W   +R GYG     DG R 
Sbjct: 423 ICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG--IEEDGDRG 480

Query: 329 E 329
           E
Sbjct: 481 E 481



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 21/66 (31%), Positives = 32/66 (48%)

Query: 275 EGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKR 334
           +G   E Y G W+A +R G GV     G+ Y+G +  ++  G G     D S  EG + R
Sbjct: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535

Query: 335 NRLVHG 340
           +  + G
Sbjct: 536 DLTLMG 541



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 305 YEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLA 350
           YEGEW   R HG G    PDG    G + +  L HG  +R LLP A
Sbjct: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQG-LEHGFGIR-LLPQA 401



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 4/75 (5%)

Query: 259 GSEASGPP---AAAPPALIEGSATEV-YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRR 314
           G E S PP    A      EG   +  Y GEW   R  G G  +  +G  + G +     
Sbjct: 331 GLEPSQPPDCRCAEYTFQAEGRLCQATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLE 390

Query: 315 HGYGRTTRPDGSREE 329
           HG+G    P  S ++
Sbjct: 391 HGFGIRLLPQASEDK 405


>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
          Length = 870

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 49/146 (33%), Positives = 67/146 (45%), Gaps = 9/146 (6%)

Query: 4   GGKFDFDDGGC-YVGGWEAGRAHGYGVCTGPGAQG-EYSGCWAHGFE-SLGVFTGPGGHS 60
           G  F    GGC Y G +  G  HG G  T   A G +Y G +      + GV+T P G  
Sbjct: 97  GEGFAAFQGGCTYRGMFSEGLMHGQG--TYIWADGLKYEGDFVKNVPMNHGVYTWPDGSM 154

Query: 61  YQGHWQQGKREGLGVERKSRW--TYRGEWLGGLK-GRSGVWESVSGLR-YAGLWKDGFQD 116
           Y+G    G R G G+ + S    +Y G W  G + G+  ++ +  G   Y G W    + 
Sbjct: 155 YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKK 214

Query: 117 GYGTETYSDGGTYQGQWQAGKRHGYG 142
           G+G   Y  G  Y+GQW+   RHG G
Sbjct: 215 GWGIRCYKSGNIYEGQWEDNMRHGEG 240



 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 43/145 (29%), Positives = 62/145 (42%), Gaps = 20/145 (13%)

Query: 15  YVGGWEAGRAHGYG-VCTGPGAQGEYSGCWAHGFES-LGVFTGPGGHSYQGHWQQGKREG 72
           Y+G W  G+ HG G +         Y G W    +   G+     G+ Y+G W+   R G
Sbjct: 179 YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHG 238

Query: 73  LGVERKSRWT-----YRGEWLGGLKGRSGV--W------ESVSGLR--YAGLWKDGFQDG 117
            G   + RW      Y G W  G++   G   W       S   LR  Y G + +G++ G
Sbjct: 239 EG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHG 295

Query: 118 YGTETYSDGGTYQGQWQAGKRHGYG 142
            G   Y+ G  Y G+W + K+HG G
Sbjct: 296 RGKFYYASGAMYDGEWVSNKKHGMG 320



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 60  SYQGHWQQGKREGLGVER-KSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGY 118
           SY+G   +G  EG G    +   TYRG +  GL    G +    GL+Y G +       +
Sbjct: 85  SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144

Query: 119 GTETYSDGGTYQGQWQAGKRHGYGV 143
           G  T+ DG  Y+G+   G R+G+G+
Sbjct: 145 GVYTWPDGSMYEGEVVNGMRNGFGM 169



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 20/56 (35%), Positives = 31/56 (55%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRL 337
           Y GE+    R G G    ++G  Y+GEW+ N++HG GR T  +G   EG +  + +
Sbjct: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHI 339



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 16/38 (42%), Positives = 23/38 (60%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGR 319
           Y G+W  + + G+G+    +G  YEG+W  N RHG GR
Sbjct: 204 YEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGR 241



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 282 YAGEWRADRRSGFG--VSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVH 339
           Y G W   +R G G     +     YEG+W+ N + G+G      G+  EG+++ N    
Sbjct: 179 YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHG 238

Query: 340 GGRVRSL 346
            GR+R L
Sbjct: 239 EGRMRWL 245



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)

Query: 272 ALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGK 331
           A  +G  T  Y G +      G G    ++GL+YEG+++ N    +G  T PDGS  EG+
Sbjct: 101 AAFQGGCT--YRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGE 158



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 16/92 (17%)

Query: 277 SATEVYAGEWRADRRSGFGV----------SQRSNGLRYEGEWLGNRRHGYGRTTRPDGS 326
           +  E Y G W    ++GFG           SQ      Y GE++   RHG G+     G+
Sbjct: 246 TTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGA 305

Query: 327 REEGKYKRNRLVHGGRVRSLLPLALRRGKVKE 358
             +G++  N+    GR      L  + G+V E
Sbjct: 306 MYDGEWVSNKKHGMGR------LTFKNGRVYE 331



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCT---GPGAQGEYSGCWAHGFESLGV 52
           GKF +  G  Y G W + + HG G  T   G   +G +S     GF  L V
Sbjct: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEV 347


>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
          Length = 870

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 49/146 (33%), Positives = 67/146 (45%), Gaps = 9/146 (6%)

Query: 4   GGKFDFDDGGC-YVGGWEAGRAHGYGVCTGPGAQG-EYSGCWAHGFE-SLGVFTGPGGHS 60
           G  F    GGC Y G +  G  HG G  T   A G +Y G +      + GV+T P G  
Sbjct: 97  GEGFAAFQGGCTYRGMFSEGLMHGQG--TYIWADGLKYEGDFVKNVPMNHGVYTWPDGSM 154

Query: 61  YQGHWQQGKREGLGVERKSRW--TYRGEWLGGLK-GRSGVWESVSGLR-YAGLWKDGFQD 116
           Y+G    G R G G+ + S    +Y G W  G + G+  ++ +  G   Y G W    + 
Sbjct: 155 YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKK 214

Query: 117 GYGTETYSDGGTYQGQWQAGKRHGYG 142
           G+G   Y  G  Y+GQW+   RHG G
Sbjct: 215 GWGIRCYKSGNIYEGQWEDNMRHGEG 240



 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 43/145 (29%), Positives = 62/145 (42%), Gaps = 20/145 (13%)

Query: 15  YVGGWEAGRAHGYG-VCTGPGAQGEYSGCWAHGFES-LGVFTGPGGHSYQGHWQQGKREG 72
           Y+G W  G+ HG G +         Y G W    +   G+     G+ Y+G W+   R G
Sbjct: 179 YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHG 238

Query: 73  LGVERKSRWT-----YRGEWLGGLKGRSGV--W------ESVSGLR--YAGLWKDGFQDG 117
            G   + RW      Y G W  G++   G   W       S   LR  Y G + +G++ G
Sbjct: 239 EG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHG 295

Query: 118 YGTETYSDGGTYQGQWQAGKRHGYG 142
            G   Y+ G  Y G+W + K+HG G
Sbjct: 296 RGKFYYASGAMYDGEWVSNKKHGMG 320



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 60  SYQGHWQQGKREGLGVER-KSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGY 118
           SY+G   +G  EG G    +   TYRG +  GL    G +    GL+Y G +       +
Sbjct: 85  SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144

Query: 119 GTETYSDGGTYQGQWQAGKRHGYGV 143
           G  T+ DG  Y+G+   G R+G+G+
Sbjct: 145 GVYTWPDGSMYEGEVVNGMRNGFGM 169



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 20/56 (35%), Positives = 31/56 (55%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRL 337
           Y GE+    R G G    ++G  Y+GEW+ N++HG GR T  +G   EG +  + +
Sbjct: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHI 339



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 16/38 (42%), Positives = 23/38 (60%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGR 319
           Y G+W  + + G+G+    +G  YEG+W  N RHG GR
Sbjct: 204 YEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGR 241



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 282 YAGEWRADRRSGFG--VSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVH 339
           Y G W   +R G G     +     YEG+W+ N + G+G      G+  EG+++ N    
Sbjct: 179 YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHG 238

Query: 340 GGRVRSL 346
            GR+R L
Sbjct: 239 EGRMRWL 245



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)

Query: 272 ALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGK 331
           A  +G  T  Y G +      G G    ++GL+YEG+++ N    +G  T PDGS  EG+
Sbjct: 101 AAFQGGCT--YRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGE 158



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 16/92 (17%)

Query: 277 SATEVYAGEWRADRRSGFGV----------SQRSNGLRYEGEWLGNRRHGYGRTTRPDGS 326
           +  E Y G W    ++GFG           SQ      Y GE++   RHG G+     G+
Sbjct: 246 TTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGA 305

Query: 327 REEGKYKRNRLVHGGRVRSLLPLALRRGKVKE 358
             +G++  N+    GR      L  + G+V E
Sbjct: 306 MYDGEWVSNKKHGMGR------LTFKNGRVYE 331



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCT---GPGAQGEYSGCWAHGFESLGV 52
           GKF +  G  Y G W + + HG G  T   G   +G +S     GF  L V
Sbjct: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEV 347


>gi|18254456 testis-specific gene A2 [Homo sapiens]
          Length = 309

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 1/88 (1%)

Query: 56  PGGHSYQGHWQQGKREGLGVER-KSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGF 114
           P G +Y+G ++ GKR G G+ + K+   Y GE++   K   G +    G RY G W +  
Sbjct: 39  PNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDL 98

Query: 115 QDGYGTETYSDGGTYQGQWQAGKRHGYG 142
           + G+G   Y +  TY G+W A +RHG G
Sbjct: 99  RHGHGVYYYINNDTYTGEWFAHQRHGQG 126



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 43/134 (32%), Positives = 59/134 (44%), Gaps = 9/134 (6%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFTGPGGHSY 61
           G+    +G  Y G +E G+ HG G+     G    GEY     HG    G F  P G  Y
Sbjct: 34  GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90

Query: 62  QGHWQQGKREGLGVERK-SRWTYRGEWLGGLKGRSGVW-ESVSGLRYAGLWKDGFQDGYG 119
           +G W    R G GV    +  TY GEW    +   G +  + +G +Y G W +G Q+G  
Sbjct: 91  EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG-T 149

Query: 120 TETYSDGGTYQGQW 133
            E       YQG++
Sbjct: 150 AELIHLNHRYQGKF 163



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 45/139 (32%), Positives = 61/139 (43%), Gaps = 13/139 (9%)

Query: 10  DDGGCYVGGW-EAGRAHGYGVCTGPGA---QGEYSGCWAHGFESLGVFTGPGGHSYQGHW 65
           +D G Y GG  EAG  HG G    P     +G Y     HG    G++    G  Y G +
Sbjct: 15  NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHG---QGIYKFKNGARYIGEY 71

Query: 66  QQGKREGLGV---ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTET 122
            + K+ G G       SR  Y GEW   L+   GV+  ++   Y G W    + G GT  
Sbjct: 72  VRNKKHGQGTFIYPDGSR--YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYL 129

Query: 123 YSD-GGTYQGQWQAGKRHG 140
           Y++ G  Y G W  G++ G
Sbjct: 130 YAETGSKYVGTWVNGQQEG 148



 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 6/106 (5%)

Query: 235 SSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGF 294
           S LGS+   L  E  +++G      +EA          L  G   + Y G +   +R G 
Sbjct: 2   SDLGSEE--LEEEGENDIGEYEGGRNEAGERHGRGRARLPNG---DTYEGSYEFGKRHGQ 56

Query: 295 GVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
           G+ +  NG RY GE++ N++HG G    PDGSR EG++  N L HG
Sbjct: 57  GIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEW-ANDLRHG 101



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 63  GHWQQGKREGLGVERKSRW-TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE 121
           G  + G+R G G  R     TY G +  G +   G+++  +G RY G +    + G GT 
Sbjct: 23  GRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTF 82

Query: 122 TYSDGGTYQGQWQAGKRHGYGV 143
            Y DG  Y+G+W    RHG+GV
Sbjct: 83  IYPDGSRYEGEWANDLRHGHGV 104



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 18/37 (48%), Positives = 20/37 (54%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYG 318
           Y GEW  D R G GV    N   Y GEW  ++RHG G
Sbjct: 90  YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQG 126



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 16/37 (43%), Positives = 23/37 (62%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYG 318
           Y GE+  +++ G G     +G RYEGEW  + RHG+G
Sbjct: 67  YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHG 103



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 3/86 (3%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCW-AHGFESLGVFT-GPGGHSYQ 62
           G F + DG  Y G W     HG+GV         Y+G W AH     G +     G  Y 
Sbjct: 80  GTFIYPDGSRYEGEWANDLRHGHGVYYYIN-NDTYTGEWFAHQRHGQGTYLYAETGSKYV 138

Query: 63  GHWQQGKREGLGVERKSRWTYRGEWL 88
           G W  G++EG          Y+G++L
Sbjct: 139 GTWVNGQQEGTAELIHLNHRYQGKFL 164



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 2/64 (3%)

Query: 280 EVYAGEWRADRRSGFGV-SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLV 338
           + Y GEW A +R G G       G +Y G W+  ++ G       +  R +GK+     V
Sbjct: 111 DTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNPV 169

Query: 339 HGGR 342
             G+
Sbjct: 170 GPGK 173



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 18/70 (25%), Positives = 26/70 (37%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGH 64
           G + + +   Y G W A + HG G         +Y G W +G +          H YQG 
Sbjct: 103 GVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHRYQGK 162

Query: 65  WQQGKREGLG 74
           +      G G
Sbjct: 163 FLNKNPVGPG 172


>gi|50355990 MORN repeat containing 3 [Homo sapiens]
          Length = 240

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 40/140 (28%), Positives = 58/140 (41%), Gaps = 8/140 (5%)

Query: 11  DGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGF-ESLGVF------TGPGGHSYQG 63
           +G  YVG WE    HG G          Y G W  G  +  G        TG     Y G
Sbjct: 34  NGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSG 93

Query: 64  HWQQGKREGLGVERKS-RWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTET 122
            W+  K+ G G++    +  Y G+W G  +   G     +G  Y G W++   +G G   
Sbjct: 94  WWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLR 153

Query: 123 YSDGGTYQGQWQAGKRHGYG 142
             +G  Y+G W+ G ++G G
Sbjct: 154 LKNGNRYEGCWERGMKNGAG 173



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 10/131 (7%)

Query: 12  GGCYVGGWEAGRAHGYGVCTGPGAQGE-----YSGCWAHGFES-LGV-FTGPGGHSYQGH 64
           G  Y G W+ G+  GYG  + P  Q       YSG W    +S  G+ F GP  + Y+G 
Sbjct: 59  GAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEY-YEGD 117

Query: 65  WQQGKREGLGVERKSRWT-YRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETY 123
           W   +R G G    S    Y G+W        G+    +G RY G W+ G ++G G   +
Sbjct: 118 WCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFH 177

Query: 124 SD-GGTYQGQW 133
            D G  ++G W
Sbjct: 178 LDHGQLFEGFW 188



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 23/69 (33%), Positives = 40/69 (57%)

Query: 276 GSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRN 335
           G    VY+G W+ D++SG+G+        YEG+W G++R G+GR    +G   EG+++ +
Sbjct: 85  GKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWEND 144

Query: 336 RLVHGGRVR 344
           +    G +R
Sbjct: 145 KPNGEGMLR 153



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 9/70 (12%)

Query: 83  YRGEWLGGLKGRSG--VWESVSGLRYAGLWKDGFQDGYGTETYSDGGT------YQGQWQ 134
           Y GEW   +K   G  VW+   G  Y G WK G +DGYGT +  D  T      Y G W+
Sbjct: 38  YVGEWEDNVKHGKGTQVWKK-KGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWK 96

Query: 135 AGKRHGYGVR 144
             K+ GYG++
Sbjct: 97  GDKKSGYGIQ 106



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 24/63 (38%), Positives = 35/63 (55%)

Query: 280 EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVH 339
           E Y G+W   +RSG+G    SNG  YEG+W  ++ +G G     +G+R EG ++R     
Sbjct: 112 EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNG 171

Query: 340 GGR 342
            GR
Sbjct: 172 AGR 174



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 26/64 (40%), Positives = 36/64 (56%), Gaps = 3/64 (4%)

Query: 94  RSGVWESVSGLRYAGLWKDGFQDGYGTETY-SDGGTYQGQWQAGKRHGYGVRQSVPYHQA 152
           RS V+ +V+G  Y G W+D  + G GT+ +   G  Y+G W+ GKR GYG   S+P  Q 
Sbjct: 27  RSQVY-AVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGT-LSLPDQQT 84

Query: 153 ALLR 156
              R
Sbjct: 85  GKCR 88



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 3/56 (5%)

Query: 280 EVYAGEWRADRRSGFGVSQ-RSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKR 334
           + Y GEW  + + G G    +  G  YEG+W   +R GYG  + PD  ++ GK +R
Sbjct: 36  DYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPD--QQTGKCRR 89



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 3/63 (4%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLG--VFTGPGGHSYQ 62
           G+  + +G  Y G WE  + +G G+         Y GCW  G ++     F    G  ++
Sbjct: 127 GRMYYSNGDIYEGQWENDKPNGEGMLRLKNG-NRYEGCWERGMKNGAGRFFHLDHGQLFE 185

Query: 63  GHW 65
           G W
Sbjct: 186 GFW 188


>gi|40316935 alsin isoform 1 [Homo sapiens]
          Length = 1657

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 12/151 (7%)

Query: 5    GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGA----QGEYSGCWAHG-FESLGVFTGPGGH 59
            G   + DG  Y G +  G   GYG    P      +  Y G W  G     GV++   G 
Sbjct: 1062 GVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVYSYASGE 1121

Query: 60   SYQGHWQQGKREGLGVERKSRWT------YRGEWLGGLKGRSGVWESVS-GLRYAGLWKD 112
             ++G +Q   R G G+ R  + T      + G+W+   K   GV++ ++ G +Y G+W+D
Sbjct: 1122 VFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQD 1181

Query: 113  GFQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
                G G      G  Y+G +   K  G GV
Sbjct: 1182 DVCQGNGVVVTQFGLYYEGNFHLNKMMGNGV 1212



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 12/96 (12%)

Query: 60   SYQGHWQQGKREGLGVERKSRWT----YRGEWLGGLKGRSGVWESVSGL-----RYAGLW 110
            +Y G W  GK  G GV    +W     Y G +  GL+   G +   +        Y G W
Sbjct: 1048 TYDGRWLSGKPHGRGV---LKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHW 1104

Query: 111  KDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQS 146
            K+G   G G  +Y+ G  ++G +Q   RHG+G+ +S
Sbjct: 1105 KEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRS 1140



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 18/69 (26%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 274  IEGSATEVYAGEWRADRRSGFGV-SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKY 332
            +  S+  ++ G+W  D+++G+GV    + G +Y G W  +   G G      G   EG +
Sbjct: 1143 LTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNF 1202

Query: 333  KRNRLVHGG 341
              N+++  G
Sbjct: 1203 HLNKMMGNG 1211



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 49/214 (22%), Positives = 74/214 (34%), Gaps = 29/214 (13%)

Query: 128  TYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGGSP 187
            TY G+W +GK HG GV   + +    +     R  L+ G+ +   P   +       G  
Sbjct: 1048 TYDGRWLSGKPHGRGV---LKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHW 1104

Query: 188  ASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLS-GLRAGGRRSSLGSKRGSLRS 246
              G   G          G  S        G F+ ++    GL   G+ +S         S
Sbjct: 1105 KEGKMCG---------QGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTS---------S 1146

Query: 247  EVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYE 306
              S  +G          G          + +  E Y G W+ D   G GV     GL YE
Sbjct: 1147 SPSMFIGQWVMDKKAGYG-------VFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYE 1199

Query: 307  GEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
            G +  N+  G G     D +  EG++  +  + G
Sbjct: 1200 GNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSG 1233


>gi|13376267 MORN repeat containing 1 [Homo sapiens]
          Length = 497

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 42/137 (30%), Positives = 59/137 (43%), Gaps = 14/137 (10%)

Query: 15  YVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPG-------GHSYQGHWQQ 67
           Y G W+AGR HG+G            G +  G    G  TG G       G ++ G +  
Sbjct: 39  YEGEWKAGRKHGHGKLLFK------DGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVL 92

Query: 68  GKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDG 126
           G+ +G GV E K+   Y GE   G++   G      G  Y G + D  + G G   + +G
Sbjct: 93  GEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNG 152

Query: 127 GTYQGQWQAGKRHGYGV 143
             Y G W   +R G+GV
Sbjct: 153 DKYDGDWVRDRRQGHGV 169



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 4/141 (2%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGF-ESLGVFTGPGGHSYQG 63
           GK  F DG  Y G +  G   G G      +   +SG +  G  +  GV     G  Y+G
Sbjct: 52  GKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEG 111

Query: 64  HWQQGKREGLG--VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE 121
               G REG G  V+R  +  Y+G +    +   G     +G +Y G W    + G+G  
Sbjct: 112 EVSHGMREGHGFLVDRDGQ-VYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVL 170

Query: 122 TYSDGGTYQGQWQAGKRHGYG 142
             +DG TY+GQW +    G G
Sbjct: 171 RCADGSTYKGQWHSDVFSGLG 191



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 3/127 (2%)

Query: 12  GGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGF-ESLGVFTGPGGHSYQGHWQQGKR 70
           G  + G +  G   GYGV     A G Y G  +HG  E  G      G  YQG +   KR
Sbjct: 83  GDTFSGQFVLGEPQGYGVMEYK-AGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141

Query: 71  EGLG-VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTY 129
            G G +  ++   Y G+W+   +   GV     G  Y G W      G G+  +  G TY
Sbjct: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTY 201

Query: 130 QGQWQAG 136
            G W  G
Sbjct: 202 YGLWING 208



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 40/122 (32%), Positives = 55/122 (45%), Gaps = 5/122 (4%)

Query: 25  HGYGVCTGPGAQGEYSGCWAHGFE-SLGVFTGPGGHSYQGHWQQGKREGLGVERKSRW-- 81
           +GYGV   P +   Y G W  G +   G      G  Y+G +  G+  G G  R   W  
Sbjct: 25  NGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEG-RRHWAWSG 83

Query: 82  -TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHG 140
            T+ G+++ G     GV E  +G  Y G    G ++G+G     DG  YQG +   KRHG
Sbjct: 84  DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG 143

Query: 141 YG 142
            G
Sbjct: 144 PG 145



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 287 RADRRSGFGVSQRSNGL-RYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGR 342
           R   R+G+GV    N   RYEGEW   R+HG+G+    DGS  EG +    +   GR
Sbjct: 20  RRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGR 76



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 19/53 (35%), Positives = 32/53 (60%)

Query: 280 EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKY 332
           +VY G +  ++R G G     NG +Y+G+W+ +RR G+G     DGS  +G++
Sbjct: 130 QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQW 182



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 72  GLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYS-DGGTYQ 130
           G+ V   S + Y GEW  G K   G      G  Y G + DG   G G   ++  G T+ 
Sbjct: 28  GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFS 87

Query: 131 GQWQAGKRHGYGVRQ 145
           GQ+  G+  GYGV +
Sbjct: 88  GQFVLGEPQGYGVME 102



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 22/72 (30%), Positives = 35/72 (48%)

Query: 273 LIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKY 332
           ++E  A   Y GE     R G G     +G  Y+G +  N+RHG G+    +G + +G +
Sbjct: 100 VMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159

Query: 333 KRNRLVHGGRVR 344
            R+R    G +R
Sbjct: 160 VRDRRQGHGVLR 171



 Score = 36.2 bits (82), Expect = 0.094
 Identities = 16/44 (36%), Positives = 23/44 (52%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDG 325
           Y G+W  DRR G GV + ++G  Y+G+W  +   G G      G
Sbjct: 155 YDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSG 198



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 20/66 (30%), Positives = 28/66 (42%)

Query: 254 STGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNR 313
           S GP       PP       +  ++   Y GEW+A R+ G G     +G  YEG ++   
Sbjct: 11  SRGPRRDPPRRPPRNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGE 70

Query: 314 RHGYGR 319
             G GR
Sbjct: 71  ITGEGR 76



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 16/57 (28%), Positives = 27/57 (47%)

Query: 280 EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
           + ++G++      G+GV +   G  YEGE     R G+G     DG   +G +  N+
Sbjct: 84  DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNK 140



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWL 310
           Y G+W +D  SG G     +G+ Y G W+
Sbjct: 178 YKGQWHSDVFSGLGSMAHCSGVTYYGLWI 206


>gi|149999376 MORN repeat containing 4 [Homo sapiens]
          Length = 146

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 40/124 (32%), Positives = 53/124 (42%), Gaps = 26/124 (20%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHG-FESLGVFTGPGGHSYQG 63
           G F +  G  Y G W+ GR HG+G        G Y G + +G F   GV T   G  Y+G
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSRYEG 64

Query: 64  HWQQGKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTET 122
            + QGK  G+GV  R    T+ GE                       +K+G  DG+G  T
Sbjct: 65  EFAQGKFNGVGVFIRYDNMTFEGE-----------------------FKNGRVDGFGLLT 101

Query: 123 YSDG 126
           + DG
Sbjct: 102 FPDG 105



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 51  GVFTGPGGHSYQGHWQQGKREGLG-VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGL 109
           G FT   G  Y+G W++G+R G G +      TY G +  GL    GV     G RY G 
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65

Query: 110 WKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
           +  G  +G G     D  T++G+++ G+  G+G+
Sbjct: 66  FAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 23/60 (38%), Positives = 34/60 (56%)

Query: 277 SATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
           S+ E Y GEW+  RR GFG    ++G  Y G +     +G+G  T  DGSR EG++ + +
Sbjct: 11  SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGK 70



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 17/93 (18%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGS----REEGKYKRNRL 337
           Y GE+   + +G GV  R + + +EGE+   R  G+G  T PDGS    R EG ++ N+L
Sbjct: 62  YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKL 121

Query: 338 VHGGRVRSLLPLALRRGKVKEKVDRAVEGARRA 370
                        LRR K    V RA   ++ A
Sbjct: 122 -------------LRREKCSAIVQRAQSASKSA 141


>gi|30520314 MORN repeat containing 4 [Homo sapiens]
          Length = 146

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 40/124 (32%), Positives = 53/124 (42%), Gaps = 26/124 (20%)

Query: 5   GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHG-FESLGVFTGPGGHSYQG 63
           G F +  G  Y G W+ GR HG+G        G Y G + +G F   GV T   G  Y+G
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSRYEG 64

Query: 64  HWQQGKREGLGV-ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTET 122
            + QGK  G+GV  R    T+ GE                       +K+G  DG+G  T
Sbjct: 65  EFAQGKFNGVGVFIRYDNMTFEGE-----------------------FKNGRVDGFGLLT 101

Query: 123 YSDG 126
           + DG
Sbjct: 102 FPDG 105



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 51  GVFTGPGGHSYQGHWQQGKREGLG-VERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGL 109
           G FT   G  Y+G W++G+R G G +      TY G +  GL    GV     G RY G 
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGE 65

Query: 110 WKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
           +  G  +G G     D  T++G+++ G+  G+G+
Sbjct: 66  FAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 23/60 (38%), Positives = 34/60 (56%)

Query: 277 SATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
           S+ E Y GEW+  RR GFG    ++G  Y G +     +G+G  T  DGSR EG++ + +
Sbjct: 11  SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGK 70



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 17/93 (18%)

Query: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGS----REEGKYKRNRL 337
           Y GE+   + +G GV  R + + +EGE+   R  G+G  T PDGS    R EG ++ N+L
Sbjct: 62  YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKL 121

Query: 338 VHGGRVRSLLPLALRRGKVKEKVDRAVEGARRA 370
                        LRR K    V RA   ++ A
Sbjct: 122 -------------LRREKCSAIVQRAQSASKSA 141


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 114/478 (23%), Positives = 157/478 (32%), Gaps = 107/478 (22%)

Query: 166  GHSDPPTPPPPLP---LPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRS 222
            G   PP PPPP P    P D   SP   S     +A PG   G SS    P   G+   +
Sbjct: 775  GRGPPPAPPPPPPPPRAPADPAASPDPPS----AVASPG--SGLSSPGPKPGDSGYETET 828

Query: 223  LLL--SGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGP---PAAAPPALIEGS 277
                      GG     G  R     E   + G+  PP      P   P   P  +++ S
Sbjct: 829  PFSPEGAFPGGGAAEEEGVPRPRAPPE-PPDPGAPRPPPDPGPLPLPGPREKPTFVVQVS 887

Query: 278  ATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRL 337
              ++              +S R +  R     LG +    G T R  G R+ G+   NR 
Sbjct: 888  TEQLL-------------MSLREDVTR---NLLGEK----GATARETGPRKAGRGPGNRE 927

Query: 338  VHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASS 397
               G  R   P  L  GK    +   V G    +    QR      +AA+    A+ +  
Sbjct: 928  KVPGLNRD--PTVLGNGKQAPSLSLPVNGV-TVLENGDQRAPGIEEKAAEN--GALGSPE 982

Query: 398  VAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGLTPSEGS 457
              EK +E   +              P RR  +  E  +    +     +   GLTP +  
Sbjct: 983  REEKVLENGEL-------------TPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSE 1029

Query: 458  PELPSSPA--SSRQPWRPPACRSPLPPGGDQGPFSSPKAW---PEEWGGA---GAQAEEL 509
             ++  +      R   RPP          + GP+ +P  W   PE WG A   G  A E 
Sbjct: 1030 DKVSENGGLRFPRNTERPP----------ETGPWRAPGPWEKTPESWGPAPTIGEPAPET 1079

Query: 510  AGYEA-------------EDEAGMQGPGPRDG---------SPLLGGCSDSSGSLREEEG 547
            +   A             E   G  GP P++G         +P  GG   + G+ R + G
Sbjct: 1080 SLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLG 1139

Query: 548  EDEEPLPPLRAPAGTEPEPIAMLVLRGSSSRGPD--AGCLTEELGEPAATERPAQPGA 603
                     RAP GT   P       G    G D  AG +     +P     P  P A
Sbjct: 1140 SGG------RAPVGTGTAP------GGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEA 1185


>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
          Length = 1316

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 60/221 (27%), Positives = 84/221 (38%), Gaps = 29/221 (13%)

Query: 389 LLKAVAASSVAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYE 448
           L+ A   S   +K +E  R++  +      M  APG   R   E  D EP     PG   
Sbjct: 703 LMPAPLLSLPEDKILETFRLSNKLKGSTDEM-SAPGAE-RGPPEDRDAEP----QPG--- 753

Query: 449 NGLTPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEE 508
              +P+  S E P + A      + P  R P  P   +G + +    PEE     +  E+
Sbjct: 754 ---SPAAESLEEPDAAAGLSSTKKAPPPRDPGTPATKEGAWEAMAVAPEE--PPPSAGED 808

Query: 509 LAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSGSLRE--------EEGEDEEPLPPLRAPA 560
           + G  A  +    G    D SPL     D+ G + E        E  E   P PP R+  
Sbjct: 809 IVGDTAPPDLCDPGSLTGDASPL---SQDAKGMIAEGPRDSALAEAPEGLSPAPPARSEE 865

Query: 561 GTEPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQP 601
             E      L++  S     DA   ++ LG P A ERP  P
Sbjct: 866 PCEQP----LLVHPSGDHARDAQDPSQSLGAPEAAERPPAP 902



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 45/162 (27%), Positives = 59/162 (36%), Gaps = 34/162 (20%)

Query: 395 ASSVAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGLTPS 454
           A +VA +    +    ++     P L  PG      S   D  PL +D+ G+   G   S
Sbjct: 793 AMAVAPEEPPPSAGEDIVGDTAPPDLCDPG------SLTGDASPLSQDAKGMIAEGPRDS 846

Query: 455 E--GSPE--LPSSPASSRQPWRPPACRSPL--PPGGD-----QGPFSS---------PKA 494
               +PE   P+ PA S +P     C  PL   P GD     Q P  S         P A
Sbjct: 847 ALAEAPEGLSPAPPARSEEP-----CEQPLLVHPSGDHARDAQDPSQSLGAPEAAERPPA 901

Query: 495 WPEEWGGAG---AQAEELAGYEAEDEAGMQGPGPRDGSPLLG 533
              +   AG     AE   G   ED A  + PGP      +G
Sbjct: 902 PVLDMAPAGHPEGDAEPSPGERVEDAAAPKAPGPSPAKEKIG 943


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 15/169 (8%)

Query: 443 SPGVYENGLTPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGA 502
           SPG   +G TPS G+  LP    +S+QP  PPA + P P GG       P   P+  G  
Sbjct: 427 SPGRGSHGQTPSPGA--LPLGRQTSQQPAGPPAQQRPPPQGGP----PQPGPGPQRQGPP 480

Query: 503 GAQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSGSLREEEGEDEEPLPPLRAPAGT 562
             Q     G     +  + G GP  GSPL       + + ++      +  PP +   G 
Sbjct: 481 LQQRPPPQG-----QQHLSGLGPPAGSPLPQRLPSPTSAPQQPA---SQAAPPTQG-QGR 531

Query: 563 EPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQPGAANPLVVGA 611
           +  P+A       ++R P +     + G P AT + +  G A P   GA
Sbjct: 532 QSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGA 580


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 15/169 (8%)

Query: 443 SPGVYENGLTPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGA 502
           SPG   +G TPS G+  LP    +S+QP  PPA + P P GG       P   P+  G  
Sbjct: 427 SPGRGSHGQTPSPGA--LPLGRQTSQQPAGPPAQQRPPPQGGP----PQPGPGPQRQGPP 480

Query: 503 GAQAEELAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSGSLREEEGEDEEPLPPLRAPAGT 562
             Q     G     +  + G GP  GSPL       + + ++      +  PP +   G 
Sbjct: 481 LQQRPPPQG-----QQHLSGLGPPAGSPLPQRLPSPTSAPQQPA---SQAAPPTQG-QGR 531

Query: 563 EPEPIAMLVLRGSSSRGPDAGCLTEELGEPAATERPAQPGAANPLVVGA 611
           +  P+A       ++R P +     + G P AT + +  G A P   GA
Sbjct: 532 QSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGA 580


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 90/334 (26%), Positives = 120/334 (35%), Gaps = 39/334 (11%)

Query: 4    GGKFDFDDGGCYVGGWEAGRAHGYGVCTGP--GAQGEYSGCWAHGFESLGVFTGPGGHSY 61
            G    FD  G   G   +   HG G       G QG  SG       S G      GHS 
Sbjct: 2258 GQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG----QSPSRGRHGSGSGHS- 2312

Query: 62   QGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE 121
              + Q G   G         +  G+  G     S  W+S      +G  + G   G+ + 
Sbjct: 2313 SSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS------SGYTQHGSGSGHSS- 2365

Query: 122  TYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPG 181
            +Y   G+  GQ   G+RHG     S  Y Q     S  R SL  G     +   P P  G
Sbjct: 2366 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHG---SGSRQSLGHGQHGSGSGQSPSPSRG 2422

Query: 182  DEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSKR 241
              G    SGS      +  G   G SS  R P   G    S L      G R S  G   
Sbjct: 2423 RHG----SGSGQSSSYSPYGSGSGWSS-SRGPYESGSGHSSGL------GHRESRSGQSS 2471

Query: 242  GSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRSN 301
            G  +   SS   ST       SG  ++       G++    +G+  +  + G G SQ S+
Sbjct: 2472 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ---HGAS----SGQSSSHGQHGSGSSQ-SS 2523

Query: 302  GLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRN 335
            G   +G   G +  G+G+  R  GSR+   Y R+
Sbjct: 2524 GYGRQGSGSG-QSPGHGQ--RGSGSRQSPSYGRH 2554



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 86/337 (25%), Positives = 115/337 (34%), Gaps = 66/337 (19%)

Query: 18  GWEAGRAHGYGVC---TGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQGK----- 69
           G  +G + GYG     +G  ++GE     +    S G   G G     GH +QG      
Sbjct: 248 GSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQH-GSGSRQSLGHGRQGSGSRQS 306

Query: 70  ----REGLGVERKSR---------WTY-RGEWLGGLKGRSGVWESVSGL-RYAGLWKDGF 114
               R G G    S          ++Y RG +  G    SG  +  SG  + +G  K G 
Sbjct: 307 PSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGS 366

Query: 115 QDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPY--HQAALLRSPRRTSLDSGHSDPPT 172
             G+ +     G T  GQ  +  +HG   RQS  Y  H++A   S  R    SG      
Sbjct: 367 GSGHSSSQGQHGST-SGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSG------ 419

Query: 173 PPPPLPLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGG 232
                      G SP  G RG      P      +   R+ ++G +   S   SG   G 
Sbjct: 420 ----------SGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGF--GH 467

Query: 233 RRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRS 292
             SS         SE SS     G     +SG           G          R +R+ 
Sbjct: 468 HESS---------SEHSSGYTQHGSGSGHSSG----------HGQHGSRSGQSSRGERQG 508

Query: 293 GFGVSQRSNGLRYEG--EWLGNRRHGYGRTTRPDGSR 327
               S  S G    G  + LG+ RHG G    P  SR
Sbjct: 509 SSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSR 545



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 90/323 (27%), Positives = 123/323 (38%), Gaps = 40/323 (12%)

Query: 18   GWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGH-SYQGHWQQGKREGLGVE 76
            G   G++  YG   G G+  + SG   HG  S G     G H S  GH     + G G  
Sbjct: 1327 GSSTGQSSSYGH-RGSGSS-QSSGYGRHGAGS-GQSPSRGRHGSGSGHSSSYGQHGSGSG 1383

Query: 77   RKSRWTYRGEWLGGLKG----RSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQ 132
              S     G   G   G     S  W+S      +G  + G   G+ + +Y   G+  GQ
Sbjct: 1384 WSSSSGRHGSGSGQSSGFGHHESSSWQS------SGCTQHGSGSGHSS-SYEQHGSRSGQ 1436

Query: 133  WQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGGSPASGSR 192
               G+RHG     S  Y Q     S  R SL  G     +   P P  G  G    SGS 
Sbjct: 1437 SSRGERHGSSSGSSSSYGQHG---SGSRQSLGHGQHGSGSGQSPSPSRGRHG----SGSG 1489

Query: 193  GGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSKRGSLRSEVSSEV 252
                 +  G   G SS +     G +   S   SGL  G R S  G   G  +   SS  
Sbjct: 1490 QSSSYSPYGSGSGWSSSR-----GPYESGSSHSSGL--GHRESRSGQSSGYGQHGSSSGH 1542

Query: 253  GSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGN 312
             ST       SG  ++       G++    +G+  +  + G G SQ S+G   +G   G 
Sbjct: 1543 SSTHGQHGSTSGQSSSCGQ---HGAS----SGQSSSHGQHGSGSSQ-SSGYGRQGSGSG- 1593

Query: 313  RRHGYGRTTRPDGSREEGKYKRN 335
            +  G+G+  R  GSR+   Y R+
Sbjct: 1594 QSPGHGQ--RGSGSRQSPSYGRH 1614



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 75/327 (22%), Positives = 105/327 (32%), Gaps = 41/327 (12%)

Query: 21   AGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFT-----GPGGHSYQGHWQQGKREGLGV 75
            +G +H  G        G+ S    HG  S G+ +     G G H   GH +QG   G   
Sbjct: 718  SGSSHSSGYRKHGSRSGQSSRSEQHGSSS-GLSSSYGQHGSGSHQSSGHGRQGSGSGHSP 776

Query: 76   ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT------ETYSDGGTY 129
             R    +  G      +  SG   S S   Y      G   G+G       + YS  G+ 
Sbjct: 777  SRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYES--GSGQASGFGQHESGSGQGYSQHGSA 834

Query: 130  QGQWQAGKRHG---------------------YGVRQSVPYHQAALLRSPRRTSLDSGHS 168
             G + +  RHG                     YG  +S  +H +   R    +    GH 
Sbjct: 835  SGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHG 894

Query: 169  DPPTPPPPLPLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGL 228
               +     P  G  G      S  G   +G G + G   +  +  + G+ +     SG 
Sbjct: 895  QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHG---SGS 951

Query: 229  RAGGRRSSLGSKRG-SLRSEV-SSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEW 286
                     GS+ G S RSE   S  GS+   G   SG   +       GS +       
Sbjct: 952  GHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQ-HGSGSGQSPSPS 1010

Query: 287  RADRRSGFGVSQRSNGLRYEGEWLGNR 313
            R    SG G S      R    W  +R
Sbjct: 1011 RGRHGSGSGQSSSYGPYRSGSGWSSSR 1037



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 79/279 (28%), Positives = 103/279 (36%), Gaps = 44/279 (15%)

Query: 55   GPGGHSYQGHWQQGK---------REGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLR 105
            G G     GH Q+G          R G G  R S     G  LG   G  G  ES SG +
Sbjct: 2529 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG-FGHHESSSG-Q 2586

Query: 106  YAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDS 165
             +   + G   G+ +  Y   G+  GQ   G+RHG     S  Y Q     S  R S  S
Sbjct: 2587 SSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSHYGQHG---SGSRQS--S 2640

Query: 166  GHSDPPTPPPPLPLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRR---S 222
            GH    +           G SP+ G  G  +          S   R+ + G +  R   S
Sbjct: 2641 GHGRQGS---------GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHS 2691

Query: 223  LLLSGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVY 282
             +     +G   SS  S+ GS     S    S G  GS  SG  +       EGS+T   
Sbjct: 2692 SVFGQHESGSGHSSAYSQHGS----GSGHFCSQGQHGS-TSGQSSTFDQ---EGSST--- 2740

Query: 283  AGEWRADRRSGFGVSQRSNGLRY---EGEWLGNRRHGYG 318
             G+  +    G G SQ S   R+    G+ L + RHG G
Sbjct: 2741 -GQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSG 2778



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 80/276 (28%), Positives = 103/276 (37%), Gaps = 38/276 (13%)

Query: 55   GPGGHSYQGHWQQGK---------REGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLR 105
            G G     GH Q+G          R G G  R S     G  LG   G  G  ES SG +
Sbjct: 1589 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG-FGHHESSSG-Q 1646

Query: 106  YAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDS 165
             +   + G   G+ +  Y   G+  GQ   G+RHG   R S  Y Q     S  R S  S
Sbjct: 1647 SSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSRSSSRYGQHG---SGSRQS--S 1700

Query: 166  GHSDPPTPPPPLPLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLL 225
            GH    +     P  G  G      S  G   +G G    +SSR    +  G    S + 
Sbjct: 1701 GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSG---RSSSRGPYESRSG---HSSVF 1754

Query: 226  SGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGE 285
                +G   SS  S+ GS     S    S G  GS  SG  +       EGS+T    G+
Sbjct: 1755 GQHESGSGHSSAYSQHGS----GSGHFCSQGQHGS-TSGQSSTFDQ---EGSST----GQ 1802

Query: 286  WRADRRSGFGVSQRSNGLRY---EGEWLGNRRHGYG 318
              +  + G G SQ S+  +     G+     RHG G
Sbjct: 1803 SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 1838



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 70/290 (24%), Positives = 101/290 (34%), Gaps = 37/290 (12%)

Query: 17   GGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQGKREGLGVE 76
            G  E+G  H           G +     HG  S    T     S  G      + G G  
Sbjct: 1755 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS 1814

Query: 77   RKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAG 136
            + S +  +G         SG  +S S  R+      G   G+ + +Y   G+  G   + 
Sbjct: 1815 QSSSYGQQG---------SGSGQSPSRGRH------GSGSGHSS-SYGQHGSGSGWSSSS 1858

Query: 137  KRHGYGVRQSVPY--HQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGGSPASGSRGG 194
             RHG G  QS  +  H+++  +S   T   SG              G        GSR G
Sbjct: 1859 GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS-------------GHSSSYEQHGSRSG 1905

Query: 195  FVLAGP--GDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSKRGSLRSEVSSEV 252
                G   G + G+SS      +G    R  L  G    G   S    RG   S  S + 
Sbjct: 1906 QSSRGEQHGSSSGSSSSYGQHGSGS---RQSLGHGQHGSGSGQSPSPSRGRHGSG-SGQS 1961

Query: 253  GSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQRSNG 302
             S GP GS +    +  P     G ++ +   E R+ + SG+G    S+G
Sbjct: 1962 SSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 2011



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 70/312 (22%), Positives = 106/312 (33%), Gaps = 47/312 (15%)

Query: 17   GGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQGKREGLGVE 76
            G +E+G +H  G+       G+ SG   HG  S        GHS   H Q G   G    
Sbjct: 1508 GPYESGSSHSSGLGHRESRSGQSSGYGQHGSSS--------GHS-STHGQHGSTSGQSSS 1558

Query: 77   ------RKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE---TYSDGG 127
                     + +  G+   G    SG     SG   +G      Q G G+    +Y   G
Sbjct: 1559 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG---SGQSPGHGQRGSGSRQSPSYGRHG 1615

Query: 128  TYQGQWQAGKRHGYGVRQS--VPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGG 185
            +  G+  +  +HG G+ +S    +H+++  +S   +   SG              G   G
Sbjct: 1616 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG-------------SGHSSG 1662

Query: 186  SPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSKRGSLR 245
                GSR G    G      + S  R    G   R+S       +G  R   GS +   R
Sbjct: 1663 YGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQS-------SGHGRQGSGSGQSPSR 1715

Query: 246  SEVSSEVGSTGPPGSEASGPPAAAPPALIEG-SATEVYAGEWRADRRSGFGVSQRSNGLR 304
                S +G +   G   SG   ++     E  S      G+  +        SQ  +G  
Sbjct: 1716 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG-- 1773

Query: 305  YEGEWLGNRRHG 316
              G +    +HG
Sbjct: 1774 -SGHFCSQGQHG 1784



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 79/276 (28%), Positives = 102/276 (36%), Gaps = 38/276 (13%)

Query: 55   GPGGHSYQGHWQQGK---------REGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLR 105
            G G     GH Q+G          R G G  R S     G  LG   G  G  ES SG +
Sbjct: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSG-FGHHESSSG-Q 2116

Query: 106  YAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDS 165
             +   + G   G+ +  Y   G+  GQ   G+RHG     S  Y Q     S  R S  S
Sbjct: 2117 SSSYSQHGSGSGHSSG-YGQHGSRSGQSSRGERHGSSSGSSSRYGQHG---SGSRQS--S 2170

Query: 166  GHSDPPTPPPPLPLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLL 225
            GH    +     P  G  G      S  G   +G G    +SSR    +  G    S + 
Sbjct: 2171 GHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSG---RSSSRGPYESRSG---HSSVF 2224

Query: 226  SGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGE 285
                +G   SS  S+ GS     S    S G  GS  SG  +       EGS+T    G+
Sbjct: 2225 GQHESGSGHSSAYSQHGS----GSGHFCSQGQHGS-TSGQSSTFDQ---EGSST----GQ 2272

Query: 286  WRADRRSGFGVSQRSNGLRY---EGEWLGNRRHGYG 318
              +  + G G SQ S+  +     G+     RHG G
Sbjct: 2273 SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 2308



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 71/314 (22%), Positives = 106/314 (33%), Gaps = 51/314 (16%)

Query: 17   GGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQGKREGLGVE 76
            G +E+G  H  G+       G+ SG   HG  S        GHS   H Q G   G    
Sbjct: 1038 GPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS--------GHS-STHGQHGSTSGQSSS 1088

Query: 77   ------RKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTE---TYSDGG 127
                     + +  G+   G    SG     SG   +G      Q G G+    +Y   G
Sbjct: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG---SGQSPGHGQRGSGSRQSPSYGRHG 1145

Query: 128  TYQGQWQAGKRHGYGVRQS--VPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGG 185
            +  G+  +  +HG G+ +S    +H+++  +S   +   SG              G   G
Sbjct: 1146 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG-------------SGHSSG 1192

Query: 186  SPASGSRGGFVLAGP--GDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSKRGS 243
                GSR G    G   G + G+SS      +G         S   +G  R   GS    
Sbjct: 1193 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSG---------SRQSSGHGRQGSGSGHSP 1243

Query: 244  LRSEVSSEVGSTGPPGSEASGPPAAAPPALIEG-SATEVYAGEWRADRRSGFGVSQRSNG 302
             R    S +G +   G   SG   ++     E  S      G+  +        SQ  +G
Sbjct: 1244 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSG 1303

Query: 303  LRYEGEWLGNRRHG 316
                G +    +HG
Sbjct: 1304 ---SGHFCSQGQHG 1314



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 71/318 (22%), Positives = 96/318 (30%), Gaps = 62/318 (19%)

Query: 17  GGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQGKREGLGVE 76
           G +E+G  H  G+       G+ SG   HG  S        GHS   H Q G   G    
Sbjct: 572 GPYESGSGHSSGLGHQESRSGQSSGYGQHGSSS--------GHS-STHGQHGSTSGQSSS 622

Query: 77  RKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAG 136
                   G+      G+ G   S S                    Y   G+  GQ  + 
Sbjct: 623 CGQHGATSGQ--SSSHGQHGSGSSQS------------------SRYGQQGSGSGQSPSR 662

Query: 137 KRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDEGG---SPASGSRG 193
            RHG     S  Y Q             SG     +  P   + G   G      SG   
Sbjct: 663 GRHGSDFGHSSSYGQHG-----------SGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSS 711

Query: 194 GFVLAGPGDADGASSRKRTPAAGGFFRRSL--LLSGL-------------RAGGRRSSLG 238
           G+   G G +  +  RK    +G   R       SGL              +G  R   G
Sbjct: 712 GYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG 771

Query: 239 SKRGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIEGSATEVYAGEWRADRRSGFGVSQ 298
           S     R    S  G +   G   SG   ++     E  + +  +G  + +  SG G SQ
Sbjct: 772 SGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQA-SGFGQHESGSGQGYSQ 830

Query: 299 RSNGLRYEGEWLGNRRHG 316
             +     G +    RHG
Sbjct: 831 HGSA---SGHFSSQGRHG 845



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 63/261 (24%), Positives = 82/261 (31%), Gaps = 77/261 (29%)

Query: 27   YGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQGK-----------REGLGV 75
            +G  +G  ++GE  G  +    S G   G G     GH Q G            R G G 
Sbjct: 1900 HGSRSGQSSRGEQHGSSSGSSSSYGQH-GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1958

Query: 76   ERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLW----KDGFQDGYG--------TETY 123
             + S +   G   G    R G +ES SG   +GL     + G   GYG        + T+
Sbjct: 1959 GQSSSYGPYGSGSGWSSSR-GPYESGSG-HSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2016

Query: 124  SDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGDE 183
               G+  GQ  +  +HG    QS                  S H             G  
Sbjct: 2017 GQHGSASGQSSSCGQHGASSGQS------------------SSH-------------GQH 2045

Query: 184  GGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSGLRAGGRRSSLGSKRGS 243
            G   +  S  G   +G G + G                     G R  G R S    R  
Sbjct: 2046 GSGSSQSSGYGRQGSGSGQSPG--------------------HGQRGSGSRQSPSYGRHG 2085

Query: 244  LRSEVSSEVGSTGPPGSEASG 264
              S  SS  G  GP   E+SG
Sbjct: 2086 SGSGRSSSSGQHGPGLGESSG 2106


>gi|109637771 calpastatin isoform l [Homo sapiens]
          Length = 654

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 212 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 270

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 271 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 329

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 330 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 380

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 381 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 425


>gi|109637769 calpastatin isoform k [Homo sapiens]
          Length = 673

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 231 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 289

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 290 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 348

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 349 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 399

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 400 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 444


>gi|109637767 calpastatin isoform j [Homo sapiens]
          Length = 667

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 225 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 283

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 284 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 342

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 343 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 393

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 394 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 438


>gi|109637765 calpastatin isoform i [Homo sapiens]
          Length = 708

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 266 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 324

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 325 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 383

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 384 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 434

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 435 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 479


>gi|109637763 calpastatin isoform h [Homo sapiens]
          Length = 769

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 327 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 385

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 386 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 444

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 445 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 495

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 496 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 540


>gi|109637761 calpastatin isoform g [Homo sapiens]
          Length = 772

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 330 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 388

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 389 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 447

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 448 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 498

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 499 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 543


>gi|109637759 calpastatin isoform f [Homo sapiens]
          Length = 750

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 308 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 366

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 367 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 425

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 426 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 476

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 477 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 521


>gi|109637757 calpastatin isoform e [Homo sapiens]
          Length = 756

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 314 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 372

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 373 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 431

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 432 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 482

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 483 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 527


>gi|27765085 calpastatin isoform b [Homo sapiens]
          Length = 686

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 244 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 302

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 303 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 361

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 362 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 412

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 413 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 457


>gi|109637753 calpastatin isoform a [Homo sapiens]
          Length = 791

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/225 (25%), Positives = 91/225 (40%), Gaps = 21/225 (9%)

Query: 341 GRVRSLLPLALRRGKVKEKV--DRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSV 398
           G VRS  P   ++ KV++    D+A+E A  A    RQ +     R+   + +A A    
Sbjct: 349 GTVRSAAPPQEKKRKVEKDTMSDQALE-ALSASLGTRQAEPELDLRSIKEVDEAKAKEEK 407

Query: 399 AEKAVE-------AARMAKLIAQDLQPMLEAPGRRPRQDSEGSDTEPLDEDSPGVYENGL 451
            EK  E         R+     +D +P+L  P  +P+  SE    + L ED     E   
Sbjct: 408 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDR-SECKE 466

Query: 452 TPSEGSPELPSSPASSRQPWRPPACRSPLPPGGDQGPFSSPKAWPEEWGGAGAQAEELAG 511
            PS+ + +   S A++  P     CR+ +          S ++ P E         + A 
Sbjct: 467 KPSKPTEKTEESKAAAPAPVSEAVCRTSM---------CSIQSAPPEPATLKGTVPDDAV 517

Query: 512 YEAEDEAGMQGPGPRDGSPLLGGCSDSSGSL-REEEGEDEEPLPP 555
               D  G +   P DG P++    + +    RE+ GE EE +PP
Sbjct: 518 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 562


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,775,884
Number of Sequences: 37866
Number of extensions: 2157191
Number of successful extensions: 18311
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 181
Number of HSP's successfully gapped in prelim test: 967
Number of HSP's that attempted gapping in prelim test: 12612
Number of HSP's gapped (non-prelim): 5801
length of query: 628
length of database: 18,247,518
effective HSP length: 108
effective length of query: 520
effective length of database: 14,157,990
effective search space: 7362154800
effective search space used: 7362154800
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press