BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo sapiens] (299 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo s... 609 e-174 gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo s... 494 e-140 gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 485 e-137 gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 478 e-135 gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa... 111 9e-25 gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens] 108 4e-24 gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens] 108 4e-24 gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo ... 100 2e-21 gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo... 91 2e-18 gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens] 87 2e-17 gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] 58 1e-08 gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens] 56 4e-08 gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens] 56 4e-08 gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens] 48 9e-06 gi|222144229 APG7 autophagy 7-like isoform c [Homo sapiens] 37 0.021 gi|222144227 APG7 autophagy 7-like isoform b [Homo sapiens] 37 0.021 gi|5453668 APG7 autophagy 7-like isoform a [Homo sapiens] 37 0.021 gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens] 35 0.10 gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens] 35 0.10 gi|193788653 hypothetical protein LOC100131897 [Homo sapiens] 31 1.5 gi|21361766 zinc finger protein 692 isoform 2 [Homo sapiens] 29 5.8 gi|209862873 zinc finger protein 692 isoform 1 [Homo sapiens] 29 5.8 gi|169214758 PREDICTED: hypothetical protein [Homo sapiens] 28 7.5 gi|169214978 PREDICTED: hypothetical protein [Homo sapiens] 28 7.5 gi|169214665 PREDICTED: hypothetical protein [Homo sapiens] 28 7.5 gi|104526627 triadin [Homo sapiens] 28 7.5 gi|27545326 SWI/SNF related, matrix associated, actin dependent ... 28 9.8 gi|119220585 apical early endosomal glycoprotein precursor [Homo... 28 9.8 >gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo sapiens] Length = 299 Score = 609 bits (1570), Expect = e-174 Identities = 299/299 (100%), Positives = 299/299 (100%) Query: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV Sbjct: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 Query: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE Sbjct: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 Query: 241 FLLQGPVSAGPSSQQLLLLRWHEGEWDCGVPWPQVNSRFGSPRDANCSMPTCIPCPLPS 299 FLLQGPVSAGPSSQQLLLLRWHEGEWDCGVPWPQVNSRFGSPRDANCSMPTCIPCPLPS Sbjct: 241 FLLQGPVSAGPSSQQLLLLRWHEGEWDCGVPWPQVNSRFGSPRDANCSMPTCIPCPLPS 299 >gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo sapiens] Length = 266 Score = 494 bits (1272), Expect = e-140 Identities = 253/266 (95%), Positives = 255/266 (95%), Gaps = 4/266 (1%) Query: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV Sbjct: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 Query: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE Sbjct: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 Query: 241 FLLQGPVSAGPSSQQLLLLRWHEGEW 266 FLLQG +A P Q +RW EG W Sbjct: 241 FLLQG--TASPRWPQ--CVRWLEGFW 262 >gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sapiens] Length = 346 Score = 485 bits (1248), Expect = e-137 Identities = 244/244 (100%), Positives = 244/244 (100%) Query: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV Sbjct: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 Query: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE Sbjct: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 Query: 241 FLLQ 244 FLLQ Sbjct: 241 FLLQ 244 >gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sapiens] Length = 346 Score = 478 bits (1229), Expect = e-135 Identities = 240/244 (98%), Positives = 241/244 (98%) Query: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV Sbjct: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 Query: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE Sbjct: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGD FGYHGYTFANLGEHEFVEE+T Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDAFGYHGYTFANLGEHEFVEEETD 180 Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 VAKVS GVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY Sbjct: 181 VAKVSHGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 Query: 241 FLLQ 244 FLLQ Sbjct: 241 FLLQ 244 >gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sapiens] Length = 1012 Score = 111 bits (277), Expect = 9e-25 Identities = 65/171 (38%), Positives = 92/171 (53%), Gaps = 3/171 (1%) Query: 19 YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGA 78 Y RQ+ + G A +R++ +RVL+ GL+GLGAE+AKNL+L GV LT+ D D A Sbjct: 15 YSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAA 74 Query: 79 QFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138 QFL+ + R+RAEAS E LN V V V T DI E F V LT + Sbjct: 75 QFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI---TEDLLLDFQVVVLTAAKLEE 131 Query: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVE 189 +KV +CHK+ + F D G G F + GE V++ T+ ++ ++ Sbjct: 132 QLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQ 182 Score = 63.9 bits (154), Expect = 2e-10 Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 10/123 (8%) Query: 17 AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVK-----GLTMLDHEQV 71 ++YD QI ++G Q++LR LLVG +G E+ K L G+ GLT++D + + Sbjct: 413 SRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHI 472 Query: 72 TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-----SFFTQF 126 + QFL R+ VGR +AE + A+ LNP + V T ++ E +FF++ Sbjct: 473 ERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 532 Query: 127 DAV 129 D V Sbjct: 533 DGV 535 >gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens] Length = 1058 Score = 108 bits (271), Expect = 4e-24 Identities = 69/188 (36%), Positives = 94/188 (50%), Gaps = 7/188 (3%) Query: 9 GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68 G ++ + Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D Sbjct: 45 GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104 Query: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128 D +QF +R +G+NRAE S R LN V V T + E F + F Sbjct: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQV 161 Query: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE----EKTKVAKV 184 V LT + ++V + CH IK D G G F + GE + E+ A V Sbjct: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221 Query: 185 SQGVEDGP 192 S +D P Sbjct: 222 SMVTKDNP 229 Score = 48.5 bits (114), Expect = 7e-06 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%) Query: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72 +YD Q+ ++G + Q++L + LVG +G E+ KN + G+ + + D + + Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509 Query: 73 PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125 + QFL R V + +++ + + +NP + V DTE I + FF Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567 Query: 126 FDAVCLTCCSRDVIVKVDQIC 146 D V + D + +D+ C Sbjct: 568 LDGVANALDNVDARMYMDRRC 588 >gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens] Length = 1058 Score = 108 bits (271), Expect = 4e-24 Identities = 69/188 (36%), Positives = 94/188 (50%), Gaps = 7/188 (3%) Query: 9 GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68 G ++ + Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D Sbjct: 45 GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104 Query: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128 D +QF +R +G+NRAE S R LN V V T + E F + F Sbjct: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQV 161 Query: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE----EKTKVAKV 184 V LT + ++V + CH IK D G G F + GE + E+ A V Sbjct: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221 Query: 185 SQGVEDGP 192 S +D P Sbjct: 222 SMVTKDNP 229 Score = 48.5 bits (114), Expect = 7e-06 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%) Query: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72 +YD Q+ ++G + Q++L + LVG +G E+ KN + G+ + + D + + Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509 Query: 73 PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125 + QFL R V + +++ + + +NP + V DTE I + FF Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567 Query: 126 FDAVCLTCCSRDVIVKVDQIC 146 D V + D + +D+ C Sbjct: 568 LDGVANALDNVDARMYMDRRC 588 >gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo sapiens] Length = 534 Score = 100 bits (248), Expect = 2e-21 Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 3/162 (1%) Query: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPG 77 +YDRQ+RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G Sbjct: 12 KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAG 71 Query: 78 AQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCC 134 F ++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T Sbjct: 72 NNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQL 131 Query: 135 SRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176 +++ + + I +G GY + EH +E Sbjct: 132 PESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 173 >gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo sapiens] Length = 528 Score = 90.5 bits (223), Expect = 2e-18 Identities = 51/158 (32%), Positives = 79/158 (50%), Gaps = 3/158 (1%) Query: 22 QIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFL 81 + RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G F Sbjct: 10 EARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFF 69 Query: 82 IRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138 ++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T Sbjct: 70 LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129 Query: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176 +++ + + I +G GY + EH +E Sbjct: 130 SLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 167 >gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens] Length = 1052 Score = 86.7 bits (213), Expect = 2e-17 Identities = 60/172 (34%), Positives = 85/172 (49%), Gaps = 5/172 (2%) Query: 13 EEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVT 72 E + A Y RQ + G A +++ S V L G+ GLG EIAKNL+LAG+K +T+ D E+ Sbjct: 38 EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97 Query: 73 PEDPGAQFLIRTGSV--GRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-SFFTQFDAV 129 D G F + V RNRAEA L+ LNP V V + + + SF ++ V Sbjct: 98 AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157 Query: 130 CLTCCSRDVIVKVDQICHKN--SIKFFTGDVFGYHGYTFANLGEHEFVEEKT 179 LT + K++ C IKF + DV G F + G+ V + T Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTT 209 Score = 39.3 bits (90), Expect = 0.004 Identities = 31/145 (21%), Positives = 59/145 (40%), Gaps = 11/145 (7%) Query: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGV-----KG-LTMLDHEQVTPEDPGAQFLIRTG 85 ++L+ + LVG +G E+ KN L GV KG +T+ D + + + QFL R Sbjct: 456 QKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPH 515 Query: 86 SVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPES-----FFTQFDAVCLTCCSRDVIV 140 + + ++ + + +N + + + E+ F+T+ D + + + Sbjct: 516 HIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVIITALDNVEARR 575 Query: 141 KVDQICHKNSIKFFTGDVFGYHGYT 165 VD C N G G+T Sbjct: 576 YVDSRCLANLRPLLDSGTMGTKGHT 600 >gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] Length = 640 Score = 57.8 bits (138), Expect = 1e-08 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 4/138 (2%) Query: 29 EAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVG 88 E + + RVL+VG G+G E+ KNL+L G + ++D + + + QFL + VG Sbjct: 10 ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVG 69 Query: 89 RNRAEASLERAQNLNPMVDVKVDTEDIEKKPE---SFFTQFDAVCLTCCSRDVIVKVDQI 145 R++A+ + E P ++ V D P+ FF QF V +R V+++ Sbjct: 70 RSKAQVAKESVLQFYPKANI-VAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRM 128 Query: 146 CHKNSIKFFTGDVFGYHG 163 C + GY G Sbjct: 129 CLAADVPLIESGTAGYLG 146 >gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens] Length = 449 Score = 55.8 bits (133), Expect = 4e-08 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 3/107 (2%) Query: 34 LRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAE 93 L +VL++G GLG E+ KNL L+G + + ++D + + + QFL R +GR +AE Sbjct: 53 LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 112 Query: 94 ASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIV 140 + E + P +V I+ ++F+ QF + C D I+ Sbjct: 113 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII---VCGLDSII 156 >gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens] Length = 463 Score = 55.8 bits (133), Expect = 4e-08 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 3/107 (2%) Query: 34 LRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAE 93 L +VL++G GLG E+ KNL L+G + + ++D + + + QFL R +GR +AE Sbjct: 67 LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 126 Query: 94 ASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIV 140 + E + P +V I+ ++F+ QF + C D I+ Sbjct: 127 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII---VCGLDSII 170 >gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens] Length = 460 Score = 48.1 bits (113), Expect = 9e-06 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 2/99 (2%) Query: 11 ISEEEAAQYDRQIRL--WGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68 +S +E +Y RQ+ L G+ Q RL + VL+VG GLG +A+ L AGV L ++D+ Sbjct: 55 LSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDY 114 Query: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVD 107 + V + Q L G+ +A ++ + LN V+ Sbjct: 115 DVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVE 153 >gi|222144229 APG7 autophagy 7-like isoform c [Homo sapiens] Length = 623 Score = 37.0 bits (84), Expect = 0.021 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%) Query: 38 RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94 + LL+G LG +A+ L+ GV+ +T +D+ +++ +P Q L G+ +A A Sbjct: 318 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 377 Query: 95 SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154 + +R Q + P V+ + I F +V L RDV +++Q+ + + F Sbjct: 378 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 434 Query: 155 TGD 157 D Sbjct: 435 LMD 437 >gi|222144227 APG7 autophagy 7-like isoform b [Homo sapiens] Length = 676 Score = 37.0 bits (84), Expect = 0.021 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%) Query: 38 RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94 + LL+G LG +A+ L+ GV+ +T +D+ +++ +P Q L G+ +A A Sbjct: 357 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 416 Query: 95 SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154 + +R Q + P V+ + I F +V L RDV +++Q+ + + F Sbjct: 417 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 473 Query: 155 TGD 157 D Sbjct: 474 LMD 476 >gi|5453668 APG7 autophagy 7-like isoform a [Homo sapiens] Length = 703 Score = 37.0 bits (84), Expect = 0.021 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%) Query: 38 RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94 + LL+G LG +A+ L+ GV+ +T +D+ +++ +P Q L G+ +A A Sbjct: 357 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 416 Query: 95 SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154 + +R Q + P V+ + I F +V L RDV +++Q+ + + F Sbjct: 417 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 473 Query: 155 TGD 157 D Sbjct: 474 LMD 476 >gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens] Length = 348 Score = 34.7 bits (78), Expect = 0.10 Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Query: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91 +++R V +VG+ G+G+ A+ L G+ L + D+++V + F + G ++ Sbjct: 13 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 71 Query: 92 AEASLERAQNLNPMVDVKVDTEDI 115 +A+ +N+NP V +V +I Sbjct: 72 VQAAEHTLRNINPDVLFEVHNYNI 95 >gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens] Length = 404 Score = 34.7 bits (78), Expect = 0.10 Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Query: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91 +++R V +VG+ G+G+ A+ L G+ L + D+++V + F + G ++ Sbjct: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 127 Query: 92 AEASLERAQNLNPMVDVKVDTEDI 115 +A+ +N+NP V +V +I Sbjct: 128 VQAAEHTLRNINPDVLFEVHNYNI 151 >gi|193788653 hypothetical protein LOC100131897 [Homo sapiens] Length = 535 Score = 30.8 bits (68), Expect = 1.5 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 168 NLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEV-DWSS 226 NL E + V +++Q +EDGP +R K+ + V K PV LE W S Sbjct: 137 NLSEQDIVSSDLAYLRLAQHLEDGP--RRVKVSHAFLPRVPKVQSNGPVSICLEAGTWRS 194 Query: 227 -EKAKAALK 234 EKA AA++ Sbjct: 195 LEKATAAIQ 203 >gi|21361766 zinc finger protein 692 isoform 2 [Homo sapiens] Length = 519 Score = 28.9 bits (63), Expect = 5.8 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Query: 213 FCPVKEALEVDWSSEKAKAALKR-TTSDYFLLQGPVSAGPSSQQLLLLRWHEGEWDCGV 270 +C +KE L S+ AK L R T+S L GP P Q L+L H +C + Sbjct: 38 WCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAGPEPLPPKGLQYLVLLSHAHSRECSL 96 >gi|209862873 zinc finger protein 692 isoform 1 [Homo sapiens] Length = 524 Score = 28.9 bits (63), Expect = 5.8 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Query: 213 FCPVKEALEVDWSSEKAKAALKR-TTSDYFLLQGPVSAGPSSQQLLLLRWHEGEWDCGV 270 +C +KE L S+ AK L R T+S L GP P Q L+L H +C + Sbjct: 43 WCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAGPEPLPPKGLQYLVLLSHAHSRECSL 101 >gi|169214758 PREDICTED: hypothetical protein [Homo sapiens] Length = 199 Score = 28.5 bits (62), Expect = 7.5 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 3/33 (9%) Query: 269 GVPWPQVNSRFGSPRDA---NCSMPTCIPCPLP 298 G P SRFG R A + S+P C CPLP Sbjct: 2 GAPGTPRLSRFGGSRGALGGSVSLPGCTKCPLP 34 >gi|169214978 PREDICTED: hypothetical protein [Homo sapiens] Length = 199 Score = 28.5 bits (62), Expect = 7.5 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 3/33 (9%) Query: 269 GVPWPQVNSRFGSPRDA---NCSMPTCIPCPLP 298 G P SRFG R A + S+P C CPLP Sbjct: 2 GAPGTPRLSRFGGSRGALGGSVSLPGCTKCPLP 34 >gi|169214665 PREDICTED: hypothetical protein [Homo sapiens] Length = 199 Score = 28.5 bits (62), Expect = 7.5 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 3/33 (9%) Query: 269 GVPWPQVNSRFGSPRDA---NCSMPTCIPCPLP 298 G P SRFG R A + S+P C CPLP Sbjct: 2 GAPGTPRLSRFGGSRGALGGSVSLPGCTKCPLP 34 >gi|104526627 triadin [Homo sapiens] Length = 729 Score = 28.5 bits (62), Expect = 7.5 Identities = 14/36 (38%), Positives = 23/36 (63%) Query: 175 VEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK 210 V + K A+VS+ VED P +K+AK + + + K+K Sbjct: 648 VTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQK 683 >gi|27545326 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform a [Homo sapiens] Length = 385 Score = 28.1 bits (61), Expect = 9.8 Identities = 38/145 (26%), Positives = 57/145 (39%), Gaps = 12/145 (8%) Query: 149 NSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVK 208 N ++ F G ++ + + L VEE+ K+ S G + P+TK D TT+ Sbjct: 34 NYLRMFRGSLYKRYPSLWRRLAT---VEERKKIVASSHGKKTKPNTK----DHGYTTLA- 85 Query: 209 KKVVFCPVKEALEV-DWSSEKAKAALKRTTSDYFLLQGPVSAGPSSQQLLLLRWHEGEWD 267 V E E+ D + EK KA T +L + A +SQ + L D Sbjct: 86 TSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLRE--QKAKRNSQWVPTLPNSSHHLD 143 Query: 268 CGVPWPQVNSRFGSPRDANCSMPTC 292 VP +R RD + P C Sbjct: 144 -AVPCSTTINRNRMGRDKKRTFPLC 167 >gi|119220585 apical early endosomal glycoprotein precursor [Homo sapiens] Length = 1137 Score = 28.1 bits (61), Expect = 9.8 Identities = 11/28 (39%), Positives = 14/28 (50%), Gaps = 3/28 (10%) Query: 266 WDCGVPWPQVNSRFGSPRDANCSMPTCI 293 WDCG+P PQ N P +C C+ Sbjct: 218 WDCGLPTPQANC---PPGHHHCQNKVCV 242 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,822,214 Number of Sequences: 37866 Number of extensions: 520722 Number of successful extensions: 1478 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 1445 Number of HSP's gapped (non-prelim): 32 length of query: 299 length of database: 18,247,518 effective HSP length: 102 effective length of query: 197 effective length of database: 14,385,186 effective search space: 2833881642 effective search space used: 2833881642 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.