BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|22538470 eomesodermin [Homo sapiens] (686 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|22538470 eomesodermin [Homo sapiens] 1418 0.0 gi|5730081 T-box, brain, 1 [Homo sapiens] 521 e-148 gi|7019549 T-box 21 [Homo sapiens] 341 1e-93 gi|18129690 T-box 4 [Homo sapiens] 194 2e-49 gi|197333868 T-box 2 [Homo sapiens] 194 2e-49 gi|18201894 T-box 5 isoform 3 [Homo sapiens] 192 1e-48 gi|18201892 T-box 5 isoform 1 [Homo sapiens] 192 1e-48 gi|31652232 T-box 5 isoform 1 [Homo sapiens] 192 1e-48 gi|18201896 T-box 5 isoform 2 [Homo sapiens] 191 3e-48 gi|5174711 T-box 1 isoform B [Homo sapiens] 184 2e-46 gi|18104952 T-box 1 isoform C [Homo sapiens] 184 2e-46 gi|18104950 T-box 1 isoform A [Homo sapiens] 184 2e-46 gi|122937456 T-box 18 [Homo sapiens] 181 3e-45 gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] 179 6e-45 gi|122937388 MAX gene associated [Homo sapiens] 177 4e-44 gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] 174 2e-43 gi|158187509 T-box 22 isoform 1 [Homo sapiens] 174 2e-43 gi|18375603 T-box 22 isoform 1 [Homo sapiens] 174 2e-43 gi|4507339 transcription factor T [Homo sapiens] 172 1e-42 gi|4827024 T-box 19 [Homo sapiens] 171 2e-42 gi|117676399 T-box transcription factor TBX20 [Homo sapiens] 171 2e-42 gi|18201900 T-box 6 [Homo sapiens] 171 2e-42 gi|55770860 T-box 15 [Homo sapiens] 169 1e-41 gi|32567784 T-box 10 [Homo sapiens] 168 2e-41 gi|158187511 T-box 22 isoform 2 [Homo sapiens] 142 1e-33 gi|122937424 one cut homeobox 3 [Homo sapiens] 65 2e-10 gi|110832843 TBP-associated factor 4 [Homo sapiens] 62 1e-09 gi|153792074 proline rich 12 [Homo sapiens] 61 4e-09 gi|48762934 alpha 2 type I collagen [Homo sapiens] 59 1e-08 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 59 1e-08 >gi|22538470 eomesodermin [Homo sapiens] Length = 686 Score = 1418 bits (3670), Expect = 0.0 Identities = 686/686 (100%), Positives = 686/686 (100%) Query: 1 MQLGEQLLVSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLS 60 MQLGEQLLVSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLS Sbjct: 1 MQLGEQLLVSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLS 60 Query: 61 CEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAA 120 CEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAA Sbjct: 61 CEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAA 120 Query: 121 AAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAP 180 AAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAP Sbjct: 121 AAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAP 180 Query: 181 NGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLY 240 NGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLY Sbjct: 181 NGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLY 240 Query: 241 GPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL 300 GPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL Sbjct: 241 GPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL 300 Query: 301 SFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGS 360 SFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGS Sbjct: 301 SFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGS 360 Query: 361 HWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQ 420 HWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQ Sbjct: 361 HWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQ 420 Query: 421 TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPF 480 TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPF Sbjct: 421 TFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPF 480 Query: 481 VNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEY 540 VNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEY Sbjct: 481 VNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEY 540 Query: 541 TSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVF 600 TSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVF Sbjct: 541 TSSTLLPYGIKSLPLQTSHALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVF 600 Query: 601 SEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKC 660 SEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKC Sbjct: 601 SEDQLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKC 660 Query: 661 EDINAEEYSKDTSKGMGGYYAFYTTP 686 EDINAEEYSKDTSKGMGGYYAFYTTP Sbjct: 661 EDINAEEYSKDTSKGMGGYYAFYTTP 686 >gi|5730081 T-box, brain, 1 [Homo sapiens] Length = 682 Score = 521 bits (1343), Expect = e-148 Identities = 306/622 (49%), Positives = 381/622 (61%), Gaps = 105/622 (16%) Query: 133 RYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLP 192 R+S D +++RY L S AP ++FPY HGP +PA + GS Sbjct: 94 RHSFDGSAADRYLLSQSSQPQSAATAPSAMFPYPGQ----HGPAHPA-----FSIGS--- 141 Query: 193 PGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYS-QGAPLYGPYPGAAAAGS 251 P + A + S G + G P Y +S QGAP Y + + Sbjct: 142 PSRYMAHHPVITNGAYNSLLSNSSPQGYPTAGYPYPQQYGHSYQGAPFY------QFSST 195 Query: 252 CGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTA 311 GL VPG +A VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNI+GL+PTA Sbjct: 196 QPGL----VPG---KAQVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTA 248 Query: 312 HYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGK 371 HYN+FV+V+LADPNHWRFQGGKWV CGKAD N+QGN++Y+HP+SPNTG+HWMRQEISFGK Sbjct: 249 HYNIFVDVILADPNHWRFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGK 308 Query: 372 LKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIA 431 LKLTNNKGA+NNN QM+VLQSLHKYQPRLH+VEV EDG ED ++P + QTFTF ETQFIA Sbjct: 309 LKLTNNKGASNNNGQMVVLQSLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIA 368 Query: 432 VTAYQNTDITQLKIDHNPFAKGFRDNYDSSH------------------QIVPGGRYGVQ 473 VTAYQNTDITQLKIDHNPFAKGFRDNYD+ + QIVPG RY + Sbjct: 369 VTAYQNTDITQLKIDHNPFAKGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMA 428 Query: 474 -SFFPEPFVNTLPQARYYNG---------ERTVPQTNGLLSPQQSEEVANP-PQRWLVTP 522 SF + FV+ +AR++ G +R+VP TNGLLSPQQ+E+ P PQRW VT Sbjct: 429 GSFLQDQFVSNYAKARFHPGAGAGPGPGTDRSVPHTNGLLSPQQAEDPGAPSPQRWFVT- 487 Query: 523 VQQPGTNKLDI--SSYESEY----TSSTLLPY---GIKSLPLQ----TSHALGYYPDPTF 569 P N+LD S+Y++ ++TLL Y G+K+LPLQ T LGYY DP Sbjct: 488 ---PANNRLDFAASAYDTATDFAGNAATLLSYAAAGVKALPLQAAGCTGRPLGYYADP-- 542 Query: 570 PAMAGWGGRGSYQ--------------------RKMAAGLPWTSRTSPTVFSE------D 603 +GWG R Q +MA P+ + + +E Sbjct: 543 ---SGWGARSPPQYCGTKSGSVLPCWPNSAAAAARMAGANPYLGEEAEGLAAERSPLPPG 599 Query: 604 QLSKEKVKEEIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSS-NENSPSIKCED 662 K K+ SSWIETP SIKS+DS+DSG+Y A KRRR+SP+++ +E+S +K E Sbjct: 600 AAEDAKPKDLSDSSWIETPSSIKSIDSSDSGIYEQA-KRRRISPADTPVSESSSPLKSEV 658 Query: 663 INAEEYSKDTSKGMGGYYAFYT 684 + + K+ +K + GYY FY+ Sbjct: 659 LAQRDCEKNCAKDISGYYGFYS 680 >gi|7019549 T-box 21 [Homo sapiens] Length = 535 Score = 341 bits (875), Expect = 1e-93 Identities = 221/523 (42%), Positives = 280/523 (53%), Gaps = 54/523 (10%) Query: 143 RYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCP 202 RY+ PG Q ++ + G G YP GA P PP F A Sbjct: 34 RYFYPEPGAQDAD----------ERRGGGSLGSPYPG--GALVP----APPSRFLGAYAY 77 Query: 203 PGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPG 262 P R Q GAG + G Y+ P G YPG + GL V G Sbjct: 78 PPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPA--GLEVSG 135 Query: 263 SGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLA 322 + V L N LW KF++HQTEMIITKQGRRMFPFLSF + GL PT+HY +FV+VVL Sbjct: 136 ---KLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLV 192 Query: 323 DPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANN 382 D +HWR+Q GKWV CGKA+ +M GN++YVHP+SPNTG+HWMRQE+SFGKLKLTNNKGA+N Sbjct: 193 DQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASN 252 Query: 383 NNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQ 442 N TQMIVLQSLHKYQPRLHIVEV + E S T FTF ETQFIAVTAYQN +ITQ Sbjct: 253 NVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQ 312 Query: 443 LKIDHNPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGER-------- 494 LKID+NPFAKGFR+N++S + V + P P P ++ G+ Sbjct: 313 LKIDNNPFAKGFRENFESMYT-------SVDTSIPSP---PGPNCQFLGGDHYSPLLPNQ 362 Query: 495 -TVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSL 553 VP P Q+++V P WL P SYE+E+ + ++ P + S Sbjct: 363 YPVPSRFYPDLPGQAKDVV-PQAYWLGAPRDH---------SYEAEFRAVSMKPAFLPSA 412 Query: 554 PLQTSHALGYYPDPTFPAM-AGWGGRGSYQRKMAAGLPWTSRTSPTVFSEDQLSKEKVKE 612 P T + YY A AGW Y KM + + + S+ + E Sbjct: 413 PGPT---MSYYRGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPE 469 Query: 613 EIGSSWIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENS 655 + G + T + +S+DSG+ KRRR+SP SS ++S Sbjct: 470 DQGPPLVWTEIAPIRPESSDSGLGEGDSKRRRVSPYPSSGDSS 512 >gi|18129690 T-box 4 [Homo sapiens] Length = 545 Score = 194 bits (494), Expect = 2e-49 Identities = 111/256 (43%), Positives = 148/256 (57%), Gaps = 14/256 (5%) Query: 209 GPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAH 268 GP G S A PG + G+P P PGA + + Sbjct: 18 GPALGEASAANAPEPALAAPGLSGAALGSP---PGPGADVVAAAAAEQTIE------NIK 68 Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 V L + LW KFH TEMIITK GRRMFP + G+NP Y + +++V AD + ++ Sbjct: 69 VGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYK 128 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 F KW+ GKA+ M G ++YVHP+SP TG+HWMRQ +SF KLKLTNN + + I Sbjct: 129 FCDNKWMVAGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFGHI 184 Query: 389 VLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHN 448 +L S+HKYQPRLHIV+ E+ ++ + T F ET FI+VT+YQN ITQLKI++N Sbjct: 185 ILNSMHKYQPRLHIVKADENNAFG-SKNTAFCTHVFPETSFISVTSYQNHKITQLKIENN 243 Query: 449 PFAKGFRDNYDSSHQI 464 PFAKGFR + DS ++ Sbjct: 244 PFAKGFRGSDDSDLRV 259 >gi|197333868 T-box 2 [Homo sapiens] Length = 712 Score = 194 bits (493), Expect = 2e-49 Identities = 136/373 (36%), Positives = 185/373 (49%), Gaps = 47/373 (12%) Query: 164 PYQAAAGAPHGPVYPAPNGARYPYGSMLP---PGGFPAAVCPPG---RAQFGPGAGAGSG 217 P AA+ + P + AP A +P + L P FPA PPG + PG + Sbjct: 4 PALAASAMAYHPFH-APRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAA 62 Query: 218 AGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLW 277 A ++ G + GP+P AA S L + V L + LW Sbjct: 63 AAAAAAAAAEAGLH-----VSALGPHPPAAHLRSLKSLEPEDEVEDDPK--VTLEAKELW 115 Query: 278 LKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTC 337 +FH+ TEM+ITK GRRMFP ++GL+ A Y + +++V AD ++F +W+ Sbjct: 116 DQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVA 175 Query: 338 GKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQ 397 GKAD M +MY+HP+SP TG WM + ++F KLKLTNN + T +L S+HKYQ Sbjct: 176 GKADPEMP-KRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFT---ILNSMHKYQ 231 Query: 398 PRLHIVEVTEDGVEDLNEPSKT-QTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456 PR HIV + L P T +T+ F ET FIAVTAYQN ITQLKID+NPFAKGFRD Sbjct: 232 PRFHIVRAN----DILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRD 287 Query: 457 NYDSSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQ 516 + + + TLP R Y E P+ +G S S +PP Sbjct: 288 TGNGRRE--------------KRKQLTLPSLRLYE-EHCKPERDGAESDASS---CDPP- 328 Query: 517 RWLVTPVQQPGTN 529 P ++P T+ Sbjct: 329 -----PAREPPTS 336 Score = 52.8 bits (125), Expect = 1e-06 Identities = 67/229 (29%), Positives = 84/229 (36%), Gaps = 33/229 (14%) Query: 37 PSAAPSPQKLDLDKASKKFSGSLSCEAVSG-EPAAASAGAPAAMLSDTDAGDAFASAAAV 95 P AAPSP +L +A +K SC A S EP S A L + A D+ AS + Sbjct: 337 PGAAPSPLRLHRARAEEK-----SCAADSDPEPERLSEERAGAPLGRSPAPDS-ASPTRL 390 Query: 96 AKPG-------------PPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSE 142 +P P + P G L A A A L+ Sbjct: 391 TEPERARERRSPERGKEPAESGGDGPFGLRSLEKERAEARRKDEGRKEAAEGKEQGLAPL 450 Query: 143 RYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCP 202 S P G+ P A + HG + P GA P L PG F P Sbjct: 451 VVQTDSASPLGA------GHLPGLAFSSHLHGQQFFGPLGAGQPL--FLHPGQFTMG--P 500 Query: 203 PGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGS 251 + G G S AGG +GGGGGPGT + G G P A+AA + Sbjct: 501 GAFSAMGMGHLLASVAGGGNGGGGGPGT---AAGLDAGGLGPAASAAST 546 Score = 31.6 bits (70), Expect = 2.6 Identities = 29/71 (40%), Positives = 34/71 (47%), Gaps = 7/71 (9%) Query: 67 EPA-AASAGAPAAMLSDTDAGDAFASAAAVAKPG------PPDGRKGSPCGEEELPSAAA 119 EPA AASA A + A ++ A A+P P G P + L AAA Sbjct: 3 EPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAA 62 Query: 120 AAAAAAAAAAA 130 AAAAAAAAA A Sbjct: 63 AAAAAAAAAEA 73 >gi|18201894 T-box 5 isoform 3 [Homo sapiens] Length = 468 Score = 192 bits (487), Expect = 1e-48 Identities = 127/327 (38%), Positives = 175/327 (53%), Gaps = 18/327 (5%) Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 V+L R LWLKFH TEMIITK GRRMFP + GLNP Y + +++V AD + ++ Sbjct: 6 VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYK 65 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 F KW GKA+ M G ++YVHP+SP TG+HWMRQ +SF KLKLTNN + + I Sbjct: 66 FADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFGHI 121 Query: 389 VLQSLHKYQPRLHIVEVTE-DGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDH 447 +L S+HKYQPRLHIV+ E +G N + T F ET FIAVT+YQN ITQLKI++ Sbjct: 122 ILNSMHKYQPRLHIVKADENNGFGSKN--TAFCTHVFPETAFIAVTSYQNHKITQLKIEN 179 Query: 448 NPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPFVN---TLPQARYYNGERTVPQTNGLLS 504 NPFAKGFR + D + + P V + + + R + ++ L S Sbjct: 180 NPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGS 239 Query: 505 PQQSEEVANPPQRWLVT-----PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSH 559 Q E + P + L+ P+ Q + + + E S+T PY + S Sbjct: 240 QYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSE 299 Query: 560 ALGYYPDPTFPAMAGWGGRGSYQRKMA 586 +Y ++P G G SY+ + A Sbjct: 300 EDSFYRS-SYPQQQGLG--ASYRTESA 323 >gi|18201892 T-box 5 isoform 1 [Homo sapiens] Length = 518 Score = 192 bits (487), Expect = 1e-48 Identities = 127/327 (38%), Positives = 175/327 (53%), Gaps = 18/327 (5%) Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 V+L R LWLKFH TEMIITK GRRMFP + GLNP Y + +++V AD + ++ Sbjct: 56 VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYK 115 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 F KW GKA+ M G ++YVHP+SP TG+HWMRQ +SF KLKLTNN + + I Sbjct: 116 FADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFGHI 171 Query: 389 VLQSLHKYQPRLHIVEVTE-DGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDH 447 +L S+HKYQPRLHIV+ E +G N + T F ET FIAVT+YQN ITQLKI++ Sbjct: 172 ILNSMHKYQPRLHIVKADENNGFGSKN--TAFCTHVFPETAFIAVTSYQNHKITQLKIEN 229 Query: 448 NPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPFVN---TLPQARYYNGERTVPQTNGLLS 504 NPFAKGFR + D + + P V + + + R + ++ L S Sbjct: 230 NPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGS 289 Query: 505 PQQSEEVANPPQRWLVT-----PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSH 559 Q E + P + L+ P+ Q + + + E S+T PY + S Sbjct: 290 QYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSE 349 Query: 560 ALGYYPDPTFPAMAGWGGRGSYQRKMA 586 +Y ++P G G SY+ + A Sbjct: 350 EDSFYRS-SYPQQQGLG--ASYRTESA 373 >gi|31652232 T-box 5 isoform 1 [Homo sapiens] Length = 518 Score = 192 bits (487), Expect = 1e-48 Identities = 127/327 (38%), Positives = 175/327 (53%), Gaps = 18/327 (5%) Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 V+L R LWLKFH TEMIITK GRRMFP + GLNP Y + +++V AD + ++ Sbjct: 56 VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYK 115 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 F KW GKA+ M G ++YVHP+SP TG+HWMRQ +SF KLKLTNN + + I Sbjct: 116 FADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFGHI 171 Query: 389 VLQSLHKYQPRLHIVEVTE-DGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDH 447 +L S+HKYQPRLHIV+ E +G N + T F ET FIAVT+YQN ITQLKI++ Sbjct: 172 ILNSMHKYQPRLHIVKADENNGFGSKN--TAFCTHVFPETAFIAVTSYQNHKITQLKIEN 229 Query: 448 NPFAKGFRDNYDSSHQIVPGGRYGVQSFFPEPFVN---TLPQARYYNGERTVPQTNGLLS 504 NPFAKGFR + D + + P V + + + R + ++ L S Sbjct: 230 NPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGS 289 Query: 505 PQQSEEVANPPQRWLVT-----PVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSH 559 Q E + P + L+ P+ Q + + + E S+T PY + S Sbjct: 290 QYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSE 349 Query: 560 ALGYYPDPTFPAMAGWGGRGSYQRKMA 586 +Y ++P G G SY+ + A Sbjct: 350 EDSFYRS-SYPQQQGLG--ASYRTESA 373 >gi|18201896 T-box 5 isoform 2 [Homo sapiens] Length = 349 Score = 191 bits (484), Expect = 3e-48 Identities = 103/192 (53%), Positives = 129/192 (67%), Gaps = 7/192 (3%) Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 V+L R LWLKFH TEMIITK GRRMFP + GLNP Y + +++V AD + ++ Sbjct: 56 VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYK 115 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 F KW GKA+ M G ++YVHP+SP TG+HWMRQ +SF KLKLTNN + + I Sbjct: 116 FADNKWSVTGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN---HLDPFGHI 171 Query: 389 VLQSLHKYQPRLHIVEVTE-DGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDH 447 +L S+HKYQPRLHIV+ E +G N + T F ET FIAVT+YQN ITQLKI++ Sbjct: 172 ILNSMHKYQPRLHIVKADENNGFGSKN--TAFCTHVFPETAFIAVTSYQNHKITQLKIEN 229 Query: 448 NPFAKGFRDNYD 459 NPFAKGFR + D Sbjct: 230 NPFAKGFRGSDD 241 >gi|5174711 T-box 1 isoform B [Homo sapiens] Length = 372 Score = 184 bits (467), Expect = 2e-46 Identities = 117/297 (39%), Positives = 153/297 (51%), Gaps = 29/297 (9%) Query: 163 FPYQAAAGA-PHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGS 221 FP A+ GA P+GP P P RY + PG P PP F P AGA + A Sbjct: 27 FPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAE 85 Query: 222 SGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFH 281 G PGA+ A + +G V L + LW +F+ Sbjct: 86 PEG-------------------PGASCAAAAKAPVKKNAKVAG--VSVQLEMKALWDEFN 124 Query: 282 RHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR--FQGGKWVTCGK 339 + TEMI+TK GRRMFP + G++P A Y + ++ V D +R F W+ GK Sbjct: 125 QLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGK 184 Query: 340 ADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPR 399 AD G +++ HP+SP G+ WM+Q +SF KLKLTNN +N + I+L S+H+YQPR Sbjct: 185 ADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH---IILNSMHRYQPR 240 Query: 400 LHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456 H+V V + +TF F ET+F AVTAYQN ITQLKI NPFAKGFRD Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297 Score = 30.0 bits (66), Expect = 7.4 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 4/69 (5%) Query: 60 SCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAA 119 S A G P AAS GA + A A PG P G P P A A Sbjct: 20 SLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAP----GPPPPPHAYPFAPA 75 Query: 120 AAAAAAAAA 128 A AA +AAA Sbjct: 76 AGAATSAAA 84 >gi|18104952 T-box 1 isoform C [Homo sapiens] Length = 495 Score = 184 bits (467), Expect = 2e-46 Identities = 117/297 (39%), Positives = 153/297 (51%), Gaps = 29/297 (9%) Query: 163 FPYQAAAGA-PHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGS 221 FP A+ GA P+GP P P RY + PG P PP F P AGA + A Sbjct: 27 FPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAE 85 Query: 222 SGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFH 281 G PGA+ A + +G V L + LW +F+ Sbjct: 86 PEG-------------------PGASCAAAAKAPVKKNAKVAG--VSVQLEMKALWDEFN 124 Query: 282 RHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR--FQGGKWVTCGK 339 + TEMI+TK GRRMFP + G++P A Y + ++ V D +R F W+ GK Sbjct: 125 QLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGK 184 Query: 340 ADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPR 399 AD G +++ HP+SP G+ WM+Q +SF KLKLTNN +N + I+L S+H+YQPR Sbjct: 185 ADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH---IILNSMHRYQPR 240 Query: 400 LHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456 H+V V + +TF F ET+F AVTAYQN ITQLKI NPFAKGFRD Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297 Score = 34.7 bits (78), Expect = 0.30 Identities = 47/193 (24%), Positives = 65/193 (33%), Gaps = 31/193 (16%) Query: 41 PSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGP 100 PS + D +A ++F AV G+PA A +LS + G A + V PG Sbjct: 331 PSGTEKDAAEARREFQRDAGGPAVLGDPAHPPQ-LLARVLSPSLPG-AGGAGGLVPLPGA 388 Query: 101 PDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPC 160 P GR P E L + A+ + L Y P Sbjct: 389 PGGRPSPPNPELRLEAPGAS----------------EPLHHHPYKY------------PA 420 Query: 161 SLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGG 220 + + + A + P YP P + Y P V P A A A + Sbjct: 421 AAYDHYLGAKSRPAP-YPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMY 479 Query: 221 SSGGGGGPGTYQY 233 SS G PG+Y Y Sbjct: 480 SSAGAAPPGSYDY 492 Score = 31.2 bits (69), Expect = 3.3 Identities = 44/137 (32%), Positives = 53/137 (38%), Gaps = 34/137 (24%) Query: 9 VSSVNLPGAHFYPLESARGGSGGSAG--HLPSAAPSPQKLDLDKASKKFSGSLSCEAVSG 66 V S +LPGA GG+GG P PSP +L + + E + Sbjct: 368 VLSPSLPGA---------GGAGGLVPLPGAPGGRPSPPNPEL-----RLEAPGASEPLHH 413 Query: 67 EPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPS--------AA 118 P PAA A D + A + P P G +G P AA Sbjct: 414 HPYKY----PAA------AYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAA 463 Query: 119 AAAAAAAAAAAATARYS 135 AAAAAAAAAAAA YS Sbjct: 464 AAAAAAAAAAAAANMYS 480 Score = 30.0 bits (66), Expect = 7.4 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 4/69 (5%) Query: 60 SCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAA 119 S A G P AAS GA + A A PG P G P P A A Sbjct: 20 SLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAP----GPPPPPHAYPFAPA 75 Query: 120 AAAAAAAAA 128 A AA +AAA Sbjct: 76 AGAATSAAA 84 >gi|18104950 T-box 1 isoform A [Homo sapiens] Length = 398 Score = 184 bits (467), Expect = 2e-46 Identities = 117/297 (39%), Positives = 153/297 (51%), Gaps = 29/297 (9%) Query: 163 FPYQAAAGA-PHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGS 221 FP A+ GA P+GP P P RY + PG P PP F P AGA + A Sbjct: 27 FPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAE 85 Query: 222 SGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFH 281 G PGA+ A + +G V L + LW +F+ Sbjct: 86 PEG-------------------PGASCAAAAKAPVKKNAKVAG--VSVQLEMKALWDEFN 124 Query: 282 RHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR--FQGGKWVTCGK 339 + TEMI+TK GRRMFP + G++P A Y + ++ V D +R F W+ GK Sbjct: 125 QLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGK 184 Query: 340 ADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPR 399 AD G +++ HP+SP G+ WM+Q +SF KLKLTNN +N + I+L S+H+YQPR Sbjct: 185 ADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH---IILNSMHRYQPR 240 Query: 400 LHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456 H+V V + +TF F ET+F AVTAYQN ITQLKI NPFAKGFRD Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297 Score = 30.0 bits (66), Expect = 7.4 Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 4/69 (5%) Query: 60 SCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAA 119 S A G P AAS GA + A A PG P G P P A A Sbjct: 20 SLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAP----GPPPPPHAYPFAPA 75 Query: 120 AAAAAAAAA 128 A AA +AAA Sbjct: 76 AGAATSAAA 84 >gi|122937456 T-box 18 [Homo sapiens] Length = 607 Score = 181 bits (458), Expect = 3e-45 Identities = 117/270 (43%), Positives = 154/270 (57%), Gaps = 21/270 (7%) Query: 198 AAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGS-CGGLG 256 AA+ PP A GP A SGA G GG +PL P G + GS L Sbjct: 73 AALPPPAGATSGP---ARSGADLERGAAGGCEDGFQQGASPLASP--GGSPKGSPARSLA 127 Query: 257 GLGVPGSGFRA-HVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNV 315 G P +A V L LW +FH TEMIITK GRRMFP + I+GL+P Y + Sbjct: 128 RPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYI 187 Query: 316 FVEVVLADPNHWRF--QGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLK 373 +++V D +R+ KW+ G AD+ + ++Y+HP+SP +G WMRQ ISF KLK Sbjct: 188 AMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPP-RVYIHPDSPASGETWMRQVISFDKLK 246 Query: 374 LTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNE----PSK--TQTFTFSET 427 LTNN+ + + I+L S+HKYQPR+H++ +D +DL+ PS + F+F ET Sbjct: 247 LTNNELDDQGH---IILHSMHKYQPRVHVIR--KDCGDDLSPIKPVPSGEGVKAFSFPET 301 Query: 428 QFIAVTAYQNTDITQLKIDHNPFAKGFRDN 457 F VTAYQN IT+LKID NPFAKGFRD+ Sbjct: 302 VFTTVTAYQNQQITRLKIDRNPFAKGFRDS 331 >gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] Length = 723 Score = 179 bits (455), Expect = 6e-45 Identities = 93/189 (49%), Positives = 123/189 (65%), Gaps = 9/189 (4%) Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 V+L + LW +FH+ TEM+ITK GRRMFP +GL+ A Y + ++++ AD ++ Sbjct: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 F +W+ GKAD M +MY+HP+SP TG WM + ++F KLKLTNN + T Sbjct: 165 FHNSRWMVAGKADPEMP-KRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFT--- 220 Query: 389 VLQSLHKYQPRLHIVEVTEDGVEDLNEPSKT-QTFTFSETQFIAVTAYQNTDITQLKIDH 447 +L S+HKYQPR HIV + L P T +T+ F ET+FIAVTAYQN ITQLKID+ Sbjct: 221 ILNSMHKYQPRFHIVRAN----DILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDN 276 Query: 448 NPFAKGFRD 456 NPFAKGFRD Sbjct: 277 NPFAKGFRD 285 Score = 39.7 bits (91), Expect = 0.009 Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 15/158 (9%) Query: 22 LESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLS 81 L ++ GG+ + +A P + AS SG S S A +GA AA L Sbjct: 500 LHPSQFAMGGAFSSMAAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLP 559 Query: 82 DTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSS 141 AS P GS AAAAAA++AAA+++ R+ +L++ Sbjct: 560 FHLQQHVLASQGLAMSPF------GSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNT 613 Query: 142 ER-------YYLQSPGPQGSELAAPCSLFPYQAAAGAP 172 R Y + P P GS L + P AAA P Sbjct: 614 MRPRLRYSPYSIPVPVPDGSSLLT--TALPSMAAAAGP 649 >gi|122937388 MAX gene associated [Homo sapiens] Length = 3114 Score = 177 bits (448), Expect = 4e-44 Identities = 93/191 (48%), Positives = 127/191 (66%), Gaps = 8/191 (4%) Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 V L N +W +F+ TEMI+TKQGRRMFP+ + I GL+ Y + +++ D + ++ Sbjct: 77 VTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNHRYK 136 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 + G W GKA+ ++ G ++++HPESP+TG +WM Q +SF KLKLTNN + I Sbjct: 137 WNGRWWEPSGKAEPHVLG-RVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGH---I 192 Query: 389 VLQSLHKYQPRLHIVEVTEDGVE--DLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKID 446 +L S+H+Y PRLH+V E VE LN P TFTF +T+F AVTAYQN ITQLKID Sbjct: 193 ILHSMHRYLPRLHLVPA-EKAVEVIQLNGPG-VHTFTFPQTEFFAVTAYQNIQITQLKID 250 Query: 447 HNPFAKGFRDN 457 +NPFAKGFRD+ Sbjct: 251 YNPFAKGFRDD 261 >gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] Length = 743 Score = 174 bits (441), Expect = 2e-43 Identities = 96/207 (46%), Positives = 126/207 (60%), Gaps = 25/207 (12%) Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 V+L + LW +FH+ TEM+ITK GRRMFP +GL+ A Y + ++++ AD ++ Sbjct: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNN----------- 377 F +W+ GKAD M +MY+HP+SP TG WM + ++F KLKLTNN Sbjct: 165 FHNSRWMVAGKADPEMP-KRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223 Query: 378 -------KGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKT-QTFTFSETQF 429 +G + TQ I L S+HKYQPR HIV + L P T +T+ F ET+F Sbjct: 224 PSDHATWQGNYSFGTQTI-LNSMHKYQPRFHIVRAN----DILKLPYSTFRTYLFPETEF 278 Query: 430 IAVTAYQNTDITQLKIDHNPFAKGFRD 456 IAVTAYQN ITQLKID+NPFAKGFRD Sbjct: 279 IAVTAYQNDKITQLKIDNNPFAKGFRD 305 Score = 39.7 bits (91), Expect = 0.009 Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 15/158 (9%) Query: 22 LESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLS 81 L ++ GG+ + +A P + AS SG S S A +GA AA L Sbjct: 520 LHPSQFAMGGAFSSMAAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLP 579 Query: 82 DTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSS 141 AS P GS AAAAAA++AAA+++ R+ +L++ Sbjct: 580 FHLQQHVLASQGLAMSPF------GSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNT 633 Query: 142 ER-------YYLQSPGPQGSELAAPCSLFPYQAAAGAP 172 R Y + P P GS L + P AAA P Sbjct: 634 MRPRLRYSPYSIPVPVPDGSSLLT--TALPSMAAAAGP 669 >gi|158187509 T-box 22 isoform 1 [Homo sapiens] Length = 520 Score = 174 bits (441), Expect = 2e-43 Identities = 95/223 (42%), Positives = 134/223 (60%), Gaps = 15/223 (6%) Query: 244 PGAAAAGSCGGLGGLGVPGSGFRA---HVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL 300 P +A+ CG G G + L LW +FH TEMIITK GRRMFP + Sbjct: 66 PSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSV 125 Query: 301 SFNINGLNPTAHYNVFVEVVLADPNHWRF--QGGKWVTCGKADNNMQGNKMYVHPESPNT 358 + GL+P Y+V ++VV D +R+ +W+ G D+ + YVHP+SP + Sbjct: 126 RVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCS 185 Query: 359 GSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNE--- 415 G WMRQ ISF ++KLTNN+ + + I+LQS+HKY+PR+H++E + DL++ Sbjct: 186 GETWMRQIISFDRMKLTNNEMDDKGH---IILQSMHKYKPRVHVIE--QGSSVDLSQIQS 240 Query: 416 -PSK-TQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456 P++ +TF+F ET+F VTAYQN IT+LKI+ NPFAKGFRD Sbjct: 241 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRD 283 >gi|18375603 T-box 22 isoform 1 [Homo sapiens] Length = 520 Score = 174 bits (441), Expect = 2e-43 Identities = 95/223 (42%), Positives = 134/223 (60%), Gaps = 15/223 (6%) Query: 244 PGAAAAGSCGGLGGLGVPGSGFRA---HVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFL 300 P +A+ CG G G + L LW +FH TEMIITK GRRMFP + Sbjct: 66 PSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSV 125 Query: 301 SFNINGLNPTAHYNVFVEVVLADPNHWRF--QGGKWVTCGKADNNMQGNKMYVHPESPNT 358 + GL+P Y+V ++VV D +R+ +W+ G D+ + YVHP+SP + Sbjct: 126 RVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCS 185 Query: 359 GSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNE--- 415 G WMRQ ISF ++KLTNN+ + + I+LQS+HKY+PR+H++E + DL++ Sbjct: 186 GETWMRQIISFDRMKLTNNEMDDKGH---IILQSMHKYKPRVHVIE--QGSSVDLSQIQS 240 Query: 416 -PSK-TQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456 P++ +TF+F ET+F VTAYQN IT+LKI+ NPFAKGFRD Sbjct: 241 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRD 283 >gi|4507339 transcription factor T [Homo sapiens] Length = 435 Score = 172 bits (435), Expect = 1e-42 Identities = 90/187 (48%), Positives = 118/187 (63%), Gaps = 14/187 (7%) Query: 276 LWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWV 335 LWL+F EMI+TK GRRMFP L N++GL+P A Y+ ++ V AD + W++ G+WV Sbjct: 51 LWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWV 110 Query: 336 TCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHK 395 GK + + +Y+HP+SPN G+HWM+ +SF K+KLTN N I+L SLHK Sbjct: 111 PGGKPEPQAP-SCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKL----NGGGQIMLNSLHK 165 Query: 396 YQPRLHIVEVTEDGVEDLNEPSKTQT-FTFSETQFIAVTAYQNTDITQLKIDHNPFAKGF 454 Y+PR+HIV V P + T F ETQFIAVTAYQN +IT LKI +NPFAK F Sbjct: 166 YEPRIHIVRV--------GGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAF 217 Query: 455 RDNYDSS 461 D + S Sbjct: 218 LDAKERS 224 >gi|4827024 T-box 19 [Homo sapiens] Length = 448 Score = 171 bits (434), Expect = 2e-42 Identities = 87/194 (44%), Positives = 121/194 (62%), Gaps = 12/194 (6%) Query: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328 + L + PLW +F EMI+TK GRRMFP L ++ GL+P A Y++ ++ V D + W+ Sbjct: 43 IILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWK 102 Query: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMI 388 + G+WV GK + + + +Y+HP+SPN G+HWM+ ISF K+KLTN N I Sbjct: 103 YVNGEWVPAGKPEVSSH-SCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL----NGGGQI 157 Query: 389 VLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHN 448 +L SLHKY+P++HIV V + +F ETQFIAVTAYQN +IT LKI +N Sbjct: 158 MLNSLHKYEPQVHIVRVG-------SAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210 Query: 449 PFAKGFRDNYDSSH 462 PFAK F D + +H Sbjct: 211 PFAKAFLDAKERNH 224 >gi|117676399 T-box transcription factor TBX20 [Homo sapiens] Length = 447 Score = 171 bits (433), Expect = 2e-42 Identities = 116/318 (36%), Positives = 162/318 (50%), Gaps = 29/318 (9%) Query: 274 RPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR--FQG 331 + LW KFH TEMIITK GRRMFP + + +G++P A Y V +++V D +R + Sbjct: 107 KELWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHR 166 Query: 332 GKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQ 391 W+ GKAD + ++YVHP+SP TG ++Q +SF K+KLTNN+ + + I+L Sbjct: 167 SSWLVAGKADPPLPA-RLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGH---IILN 222 Query: 392 SLHKYQPRLHIVEVTEDGVEDLNEPSKT-QTFTFSETQFIAVTAYQNTDITQLKIDHNPF 450 S+HKYQPR+HI++ + LN S+ +TF F ET F AVTAYQN IT+LKID NPF Sbjct: 223 SMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPF 282 Query: 451 AKGFRDNYDSSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEE 510 AKGFRD S ++ R V+S + P R Y GE V +P + Sbjct: 283 AKGFRD----SSRLTDIERESVESLIQKHSYARSP-IRTYGGEEDVLGDESQTTPNRGSA 337 Query: 511 VANPP----QRWLVTPVQQP-----------GTNKLDISSYESEYTSSTLLPYGIKSLPL 555 W+ + P GT+ I++ +L PY +PL Sbjct: 338 FTTSDNLSLSSWVSSSSSFPGFQHPQSLTALGTSTASIATPIPHPIQGSLPPYSRLGMPL 397 Query: 556 QTSHALGYY--PDPTFPA 571 S PTFP+ Sbjct: 398 TPSAIASSMQGSGPTFPS 415 >gi|18201900 T-box 6 [Homo sapiens] Length = 436 Score = 171 bits (433), Expect = 2e-42 Identities = 94/220 (42%), Positives = 133/220 (60%), Gaps = 16/220 (7%) Query: 238 PLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMF 297 P G P +A + L G+ + L NR LW +F TEMIITK GRRMF Sbjct: 71 PAMGTEPAPSAPEALHSLPGVSLS---------LENRELWKEFSSVGTEMIITKAGRRMF 121 Query: 298 PFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPN 357 P ++ GL+P A Y ++V+ D +R+QG +W GKA+ + +++Y+HP+SP Sbjct: 122 PACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLP-DRVYIHPDSPA 180 Query: 358 TGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPS 417 TG+HWMRQ +SF ++KLTN+ + + ++L S+HKYQPR+H+V + + + Sbjct: 181 TGAHWMRQPVSFHRVKLTNSTLDPHGH---LILHSMHKYQPRIHLVRAAQLCSQHWGGMA 237 Query: 418 KTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDN 457 +F F ET FI+VTAYQN ITQLKI NPFAKGFR+N Sbjct: 238 ---SFRFPETTFISVTAYQNPQITQLKIAANPFAKGFREN 274 >gi|55770860 T-box 15 [Homo sapiens] Length = 496 Score = 169 bits (427), Expect = 1e-41 Identities = 127/367 (34%), Positives = 179/367 (48%), Gaps = 49/367 (13%) Query: 276 LWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRF--QGGK 333 LW +FH TEMIITK GRRMFP + I GL+P Y + +++V D +R+ K Sbjct: 16 LWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSK 75 Query: 334 WVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSL 393 W+ G AD+ + ++Y+HP+S +G WMRQ +SF KLKLTNN+ + + I+L S+ Sbjct: 76 WMVAGNADSPVPP-RVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGH---IILHSM 131 Query: 394 HKYQPRLHIVEVTEDGVEDLNEPSK-------TQTFTFSETQFIAVTAYQNTDITQLKID 446 HKYQPR+H++ +D DL+ P+K +TF F ET F VTAYQN IT+LKID Sbjct: 132 HKYQPRVHVIR--KDFSSDLS-PTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKID 188 Query: 447 HNPFAKGFRDN------YDSSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTN 500 NPFAKGFRD+ ++ + R V++ E F Q G + Sbjct: 189 RNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSST 248 Query: 501 GLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSH- 559 G SP S + +P P N ++ ES+ + L Y P S+ Sbjct: 249 GTPSPSASSHLLSPS---CSPPTFHLAPNTFNVGCRESQLCNLNLSDYP----PCARSNM 301 Query: 560 -ALGYYPDPTFPAMAGWGGRGSYQRKMAAGLPWTSRTSPTVFSEDQLSKEKVKEEIGSSW 618 AL YP G S ++ +G TS T P+ Q + + S Sbjct: 302 AALQSYP----------GLSDSGYNRLQSGT--TSATQPSETFMPQRTPSLI------SG 343 Query: 619 IETPPSI 625 I TPPS+ Sbjct: 344 IPTPPSL 350 >gi|32567784 T-box 10 [Homo sapiens] Length = 385 Score = 168 bits (425), Expect = 2e-41 Identities = 98/236 (41%), Positives = 131/236 (55%), Gaps = 12/236 (5%) Query: 239 LYGPYPGAAAAGSCGGLGGLGVPGSG------FRAHVYLCNRPLWLKFHRHQTEMIITKQ 292 L P+P S G G G R V L +PLW +F++ TEMI+TK Sbjct: 31 LGSPFPSGPCTSSTGAQAVAEPTGQGPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKA 90 Query: 293 GRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR--FQGGKWVTCGKADNNMQGNKMY 350 GRRMFP I G++ A Y + ++ + D +R F W+ GKAD G +++ Sbjct: 91 GRRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPG-RVH 149 Query: 351 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV 410 HP+SP G+ WMRQ +SF KLKLTNN +N + I+L S+H+YQPR H+V V Sbjct: 150 FHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGH---IILNSMHRYQPRFHVVFVDPRKD 206 Query: 411 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSSHQIVP 466 + ++F F+ETQF AVTAYQN ITQLKI NPFAKGFR++ S + P Sbjct: 207 SERYAQENFKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESDLDSWPVAP 262 >gi|158187511 T-box 22 isoform 2 [Homo sapiens] Length = 400 Score = 142 bits (357), Expect = 1e-33 Identities = 74/168 (44%), Positives = 109/168 (64%), Gaps = 12/168 (7%) Query: 296 MFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRF--QGGKWVTCGKADNNMQGNKMYVHP 353 MFP + + GL+P Y+V ++VV D +R+ +W+ G D+ + YVHP Sbjct: 1 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60 Query: 354 ESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDL 413 +SP +G WMRQ ISF ++KLTNN+ + + I+LQS+HKY+PR+H++E + DL Sbjct: 61 DSPCSGETWMRQIISFDRMKLTNNEMDDKGH---IILQSMHKYKPRVHVIE--QGSSVDL 115 Query: 414 NE----PSK-TQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456 ++ P++ +TF+F ET+F VTAYQN IT+LKI+ NPFAKGFRD Sbjct: 116 SQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRD 163 >gi|122937424 one cut homeobox 3 [Homo sapiens] Length = 494 Score = 65.5 bits (158), Expect = 2e-10 Identities = 84/268 (31%), Positives = 100/268 (37%), Gaps = 42/268 (15%) Query: 22 LESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSL------SCEAVSGEPAAASAGA 75 L+ GG GG AG A + D + +G L +CEA G + Sbjct: 54 LDGGGGGGGGGAGGAGGAGSAGGGADF---RGELAGPLHPAMGMACEA-PGLGGTYTTLT 109 Query: 76 PAAMLSDTDA-GDAF---ASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAAT 131 P L A D F A+AAAVA G G P+AA AA+ Sbjct: 110 PLQHLPPLAAVADKFHQHAAAAAVA------GAHGGHPHAHPHPAAAPPPPPPPQRLAAS 163 Query: 132 ARYSMDSLSSERYYLQSPG----PQGSELAA--------PCSLFPYQAAAGAPHGPVYPA 179 S + ER L S G P G EL A P +L P A P P P Sbjct: 164 VSGSFTLMRDERAALASVGHLYGPYGKELPAMGSPLSPLPNALPPALHGAPQPPPPPPPP 223 Query: 180 PNGARYPYG-----SMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYS 234 P A P G +LPP F GRA+ G G GG+ GG G G+ Sbjct: 224 PLAAYGPPGHLAGDKLLPPAAFEPHAALLGRAEDALARGLPGGGGGTGSGGAGSGS---- 279 Query: 235 QGAPLYGPYPGAAAAGSCGGLGGLGVPG 262 A L P G AAAG+ G GG G PG Sbjct: 280 -AAGLLAPLGGLAAAGAHGPHGGGGGPG 306 Score = 35.0 bits (79), Expect = 0.23 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 195 GFPAAVCPPGRAQFGPGAGAGSGAGGSSGGG--GGPGTYQYSQGAPLYGPYPGAAAAGSC 252 G P V G G G G GAGG+ G G GG ++ PL +P A Sbjct: 42 GRPGLVAGMASLLDGGGGGGGGGAGGAGGAGSAGGGADFRGELAGPL---HPAMGMACEA 98 Query: 253 GGLGG 257 GLGG Sbjct: 99 PGLGG 103 Score = 31.6 bits (70), Expect = 2.6 Identities = 27/76 (35%), Positives = 30/76 (39%), Gaps = 28/76 (36%) Query: 188 GSMLPPGGFPAAVCP------PGRAQFGPGAGAGSGA---GGSSGGGGGPGTYQYSQGAP 238 G +L PG +A PGR PG AG + GG GGGGG G Sbjct: 20 GELLSPGHARSAAAQHRGLVAPGR----PGLVAGMASLLDGGGGGGGGGAG--------- 66 Query: 239 LYGPYPGAAAAGSCGG 254 GA AGS GG Sbjct: 67 ------GAGGAGSAGG 76 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 62.4 bits (150), Expect = 1e-09 Identities = 81/274 (29%), Positives = 100/274 (36%), Gaps = 52/274 (18%) Query: 15 PGAHFYPLESARGGSGGSAGHLPS----------AAPSPQKLDLDKASKKFSGSLSCEAV 64 PGA P + R GG P A P+P L + +GS C V Sbjct: 83 PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS--CAPV 140 Query: 65 SGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPC-GEEELPSAAAAAAA 123 A A+ PA AG A +A A PGP G P G+ P AA Sbjct: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG 200 Query: 124 AAAA-----AAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYP 178 +AA AAA A +++ + L P G+ + P P+ AA AP P P Sbjct: 201 SAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTP----PFVGAA-APPAPAAP 255 Query: 179 APNGARYPYG-------------SMLPPGGFPA-------AVCPPGRAQFGPGAGA---- 214 +P A P ++ P G PA AV PP AQ G AGA Sbjct: 256 SPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAP 315 Query: 215 GSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAA 248 AGG +G G PG GA P PG A Sbjct: 316 APAAGGPAGVSGQPG-----PGAAAAAPAPGVKA 344 Score = 61.2 bits (147), Expect = 3e-09 Identities = 70/231 (30%), Positives = 78/231 (33%), Gaps = 44/231 (19%) Query: 22 LESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLS 81 LES S HL P + A PAA + GAP A Sbjct: 29 LESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPE 88 Query: 82 DTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSS 141 AG A +PGPP R+ P A A AA Sbjct: 89 PPPAGRARPGGGGPQRPGPPSPRR---------PLVPAGPAPPAAKL------------- 126 Query: 142 ERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVC 201 P P+GS A C+ P AAA GP PAP G P G PAA+ Sbjct: 127 ------RPPPEGS--AGSCA--PVPAAAAVAAGP-EPAPAGPAKPAG--------PAALA 167 Query: 202 PPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQG-APLYGPYPGAAAAGS 251 RA GPG G G G G G GPG Q G A L + AA A S Sbjct: 168 --ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVS 216 Score = 36.2 bits (82), Expect = 0.10 Identities = 58/206 (28%), Positives = 66/206 (32%), Gaps = 43/206 (20%) Query: 16 GAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGA 75 GA P +A A P+AAP P A P AG Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPP--------------PAPATLARPPGHPAGP 290 Query: 76 PAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYS 135 P A + A +A A P P G P G P AAAAA A A Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPA-AGGPAGVSGQPGPGAAAAAPAPGVKA----- 344 Query: 136 MDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGG 195 S + +Q+ P LAA P AA GP GA LP Sbjct: 345 ----ESPKRVVQAAPPAAQTLAAS---GPASTAASMVIGPTM---QGA-------LPS-- 385 Query: 196 FPAAVCPPGRAQFGPGAGAGSGAGGS 221 PAAV PP G G GA G+ Sbjct: 386 -PAAVPPPAP---GTPTGLPKGAAGA 407 Score = 32.7 bits (73), Expect = 1.1 Identities = 35/120 (29%), Positives = 46/120 (38%), Gaps = 8/120 (6%) Query: 16 GAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGA 75 GA P +A G +G S P AA + + S K + A A+ A Sbjct: 310 GAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAST 369 Query: 76 PAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYS 135 A+M+ A S AAV P P G+P G LP AA A + + TA S Sbjct: 370 AASMVIGPTMQGALPSPAAVPPPAP-----GTPTG---LPKGAAGAVTQSLSRTPTATTS 421 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 60.8 bits (146), Expect = 4e-09 Identities = 80/302 (26%), Positives = 106/302 (35%), Gaps = 58/302 (19%) Query: 6 QLLVSSVNLPGAHFYPLESARGG--SGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEA 63 +L +S LPG+ +P SA S G P PS L S +G LS Sbjct: 129 ELFISGA-LPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHD 187 Query: 64 VSGEPAAASAGAPAAMLSDTDAGDAFASAAAVA-------KPGPPDGRKGSPCGEEELPS 116 V + + P+++ + AG A + +PGPPD P LP+ Sbjct: 188 VLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPD----PPPPPRHLPT 243 Query: 117 AAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCS---LFPYQAAAGAPH 173 A+++AAAAA + S + + +PGP E A P + YQ A A Sbjct: 244 QFNLLASSSAAAAAAEQSSPQLYN---FSGAAPGPPPPERALPRQDTVIKHYQRPASAQP 300 Query: 174 GPVYPAPN--------GARYPY--------------GSMLPPGGFPAAVCPPGRAQFGPG 211 P P + G YP G P G P+ P G G Sbjct: 301 PPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASG 360 Query: 212 AGAGSGAGGSSGGGGGPGTYQ-------YSQGAPLYG---------PYPGAAAAGSCGGL 255 G A G G GGG G Y+ Y G YG P P + A C L Sbjct: 361 RATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSL 420 Query: 256 GG 257 GG Sbjct: 421 GG 422 Score = 44.3 bits (103), Expect = 4e-04 Identities = 67/269 (24%), Positives = 84/269 (31%), Gaps = 44/269 (16%) Query: 21 PLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAV-------SGEPAAASA 73 P + GG+GG G SP K K G+ + A + P S Sbjct: 365 PEAAGGGGAGGGGGGYRPIIQSPGY----KTGKGGYGAAAGGATRPPPPRSTATPKCQSL 420 Query: 74 GAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAA------ 127 G PAA + A A + PG P G G + A + A + Sbjct: 421 GGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP 480 Query: 128 ----------AAATARYSMDSLSSERYYLQS---PGPQGSELAAPCSLFPYQAAAGAPHG 174 A YS D L + Y +Q PGP P + + G H Sbjct: 481 QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTG--HS 538 Query: 175 PVYPAPNGARYPYGSMLPPGG--FPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQ 232 P G P S L GG P+ + P Q P G G G G PG Y Sbjct: 539 PALSGHGGGWGP--SSLGGGGEASPSHIIRP--LQSPPATGRPPGVGSP----GAPGKYL 590 Query: 233 YS--QGAPLYGPYPGAAAAGSCGGLGGLG 259 S AP P + A GG G G Sbjct: 591 SSVLASAPFLAPPGAGSYAAGAGGYKGKG 619 Score = 42.0 bits (97), Expect = 0.002 Identities = 75/303 (24%), Positives = 99/303 (32%), Gaps = 73/303 (24%) Query: 23 ESARGGSGGSAGHL-----PSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPA 77 ++ +GG G +AG P + +P+ L + ++ + A A S G P Sbjct: 390 KTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQ 449 Query: 78 AMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMD 137 +L G F A P G P + PS A + YS D Sbjct: 450 GLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP----QPPSGPPPPGLATCQS-----YSPD 500 Query: 138 SLSSERYYLQS---PGP----QGSELAAPCSLF-----PYQAAAGAPHGPVYPAPNGARY 185 L + Y +Q PGP QG A+P + P + G GP G Sbjct: 501 QLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEAS 560 Query: 186 PYGSMLPPGGFPAAVCPPGRAQFG------------------PGAGAG-SGAGGSSGGG- 225 P + P PA PPG G PGAG+ +GAGG G G Sbjct: 561 PSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD 620 Query: 226 -----GGPG------------TYQYSQGAP----------LYGPYPGAAAAGSCGGLGGL 258 GPG Q+ AP L G A A+ GG GG Sbjct: 621 GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGA 680 Query: 259 GVP 261 G P Sbjct: 681 GGP 683 Score = 37.0 bits (84), Expect = 0.061 Identities = 45/152 (29%), Positives = 54/152 (35%), Gaps = 26/152 (17%) Query: 98 PGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELA 157 PG + K P G + A A+ A AA + R +QSPG + + Sbjct: 341 PGAGEPSKAGPSG-----ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGG 395 Query: 158 APCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSG 217 Y AAAG P P P P L G PAA G+A SG Sbjct: 396 -------YGAAAGGATRP--PPPRSTATPKCQSL---GGPAAAYATGKA---------SG 434 Query: 218 AGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAA 249 AGG+ G PG Q G YG G A Sbjct: 435 AGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQA 466 Score = 33.9 bits (76), Expect = 0.51 Identities = 62/221 (28%), Positives = 75/221 (33%), Gaps = 40/221 (18%) Query: 69 AAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPS----AAAAAAAA 124 A++SA A AA S + F+ AA PGPP + P + + A+A Sbjct: 249 ASSSAAAAAAEQSSPQLYN-FSGAA----PGPPPPERALPRQDTVIKHYQRPASAQPPPP 303 Query: 125 AAAAAATARY-----SMDSLSSERYYLQSP---GPQGSELAAPCSLFPYQAAAGAPH--- 173 A A Y S S+ SP G P P A AGA Sbjct: 304 PPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRAT 363 Query: 174 GPVYPAPNGARYPYGSMLP----------PGGFPAAVC-----PPGRAQFGP-----GAG 213 GP GA G P GG+ AA PP R+ P G Sbjct: 364 GPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGP 423 Query: 214 AGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGG 254 A + A G + G GG G YS G P P A G GG Sbjct: 424 AAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGG 464 Score = 32.7 bits (73), Expect = 1.1 Identities = 36/117 (30%), Positives = 44/117 (37%), Gaps = 29/117 (24%) Query: 148 SPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGS----MLPPGGFPA----- 198 SPG G L++ + P+ A GA Y A G G + PGG PA Sbjct: 582 SPGAPGKYLSSVLASAPFLAPPGAGS---YAAGAGGYKGKGDGSELLAGPGGPPAERTED 638 Query: 199 ----------AVCPP------GRAQFGPGAGAGSGAGGSSGGGGGPGT-YQYSQGAP 238 A PP G A A G GGS G GG PGT Y+ ++ P Sbjct: 639 EEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDP 695 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 59.3 bits (142), Expect = 1e-08 Identities = 68/241 (28%), Positives = 84/241 (34%), Gaps = 36/241 (14%) Query: 28 GSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASA-GAPAAMLSDTDAG 86 G+ G +G PS P + K G G P A GAP A+ + AG Sbjct: 631 GTAGPSG--PSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAG 688 Query: 87 -DAFASAAAVAKPGPPDGRKGSPCGEEEL----PSAAAAAAAAAAAAAATARYSMDSLSS 141 A A P P G +GSP E+ P+ A A AA A Sbjct: 689 ATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKG 748 Query: 142 ERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVC 201 E + GP G+ A P+GP P P G+R G Sbjct: 749 ENGVVGPTGPVGA------------AGPAGPNGP--PGPAGSRGDGG------------- 781 Query: 202 PPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVP 261 PPG F PGA +G G SG G PG + L GP G G +G +G P Sbjct: 782 PPGMTGF-PGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPP 840 Query: 262 G 262 G Sbjct: 841 G 841 Score = 52.4 bits (124), Expect = 1e-06 Identities = 73/249 (29%), Positives = 85/249 (34%), Gaps = 41/249 (16%) Query: 28 GSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLSDTDAGD 87 GS GS G + A P S G GE A PA Sbjct: 235 GSDGSVGPVGPAGPI--------GSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVG 286 Query: 88 AFASAAAVAKPGPPD-----GRKGSP-----CGEEELPSAAAAAAAAAAAAAATARYSMD 137 + V PG P G KG+ G LP AA A AR Sbjct: 287 LPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGAR---- 342 Query: 138 SLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYG---SMLPPG 194 L E PGP GS+ + P A P GP G R P G S PPG Sbjct: 343 GLVGE------PGPAGSKGESGNKGEPGSAGPQGPPGP--SGEEGKRGPNGEAGSAGPPG 394 Query: 195 GFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGG 254 PPG + PG+ GA G +G G PG+ S A + GP A G G Sbjct: 395 -------PPG-LRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL 446 Query: 255 LGGLGVPGS 263 +G G+PGS Sbjct: 447 MGPRGLPGS 455 Score = 49.3 bits (116), Expect = 1e-05 Identities = 78/275 (28%), Positives = 94/275 (34%), Gaps = 52/275 (18%) Query: 14 LPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASA 73 LPG P G+ G+ G + P+ SK SG+ GEP +A Sbjct: 323 LPGPRGIPGPVGAAGATGARGLVGEPGPA--------GSKGESGN------KGEPGSAGP 368 Query: 74 GAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSA--------------AA 119 P + A + PGPP G +GSP G LP A A+ Sbjct: 369 QGPPGPSGEEGKRGPNGEAGSAGPPGPP-GLRGSP-GSRGLPGADGRAGVMGPPGSRGAS 426 Query: 120 AAAAAAAAAAATARYSMDSLSSERYYLQSPG---PQGSELAAPCSLFPYQAAAGAPHGPV 176 A R L R SPG P G E P L G P GP+ Sbjct: 427 GPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKE--GPVGL---PGIDGRP-GPI 480 Query: 177 YPAPNGARYPYGSMLPPG-----GFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTY 231 PA GAR G++ PG G P G A GA G G++G G PG Sbjct: 481 GPA--GARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLA-GARGAPGPDGNNGAQGPPGPQ 537 Query: 232 QYSQGAPLYGPYPG----AAAAGSCGGLGGLGVPG 262 G GP PG G G G +G PG Sbjct: 538 GVQGGKGEQGP-PGPPGFQGLPGPSGPAGEVGKPG 571 Score = 42.4 bits (98), Expect = 0.001 Identities = 68/264 (25%), Positives = 80/264 (30%), Gaps = 29/264 (10%) Query: 26 RGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLSDTDA 85 +G GG P P Q L G + GE P Sbjct: 537 QGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGE 596 Query: 86 GDAFASAAAVAKPGP-----PDGRKGSP-------CGEEELPSAAAAAAAAAAAAAATAR 133 A + GP PDG KG P PS AA Sbjct: 597 SGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGE 656 Query: 134 YSMDSLSSERYYLQSPGPQGSELA-------APCSLFPYQAAAGAPHGPVYPA-PNGARY 185 L E + +PG G+ A P + AGA GP PA P G+ Sbjct: 657 KGEPGLRGE---IGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAA-GPAGPAGPRGSPG 712 Query: 186 PYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPY-- 243 G + P G P P A PGA GA G G G G A GP Sbjct: 713 ERGEVGPAG--PNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP 770 Query: 244 PGAAAAGSCGGLGGL-GVPGSGFR 266 PG A + GG G+ G PG+ R Sbjct: 771 PGPAGSRGDGGPPGMTGFPGAAGR 794 Score = 39.7 bits (91), Expect = 0.009 Identities = 90/369 (24%), Positives = 112/369 (30%), Gaps = 122/369 (33%) Query: 9 VSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEP 68 V +V PG + E G G+AG P P PQ G L + G P Sbjct: 834 VGAVGPPG---FAGEKGPSGEAGTAG--PPGTPGPQ------------GLLGAPGILGLP 876 Query: 69 AA-ASAGAPAAMLSDTDAGDAFASAAAVAKPGP-----PDGRKGSPCGEEELPSAAAAAA 122 + G P A AV +PGP P G +G P G P A Sbjct: 877 GSRGERGLPGV-------------AGAVGEPGPLGIAGPPGARGPP-GAVGSPGVNGAPG 922 Query: 123 AAAAAA-----AATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVY 177 A R ER Y + GP G+ A A PHGPV Sbjct: 923 EAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGA------------AGAPGPHGPVG 970 Query: 178 PA----------PNGARYPYGSMLPPG-----------GFPAAVCP-------------- 202 PA P+G P G++ P G G P P Sbjct: 971 PAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQG 1030 Query: 203 -PGRA----------QFGPGAGAG-SGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAG 250 PG A GP G +G G +G G G A + GP AG Sbjct: 1031 LPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAG 1090 Query: 251 SCGGLGGLGVPG-------SGFRAHVYLCNRP--------------LWLKFHRHQTEMII 289 G G G PG G+ Y ++P LK +Q E ++ Sbjct: 1091 PPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIETLL 1150 Query: 290 TKQGRRMFP 298 T +G R P Sbjct: 1151 TPEGSRKNP 1159 Score = 38.5 bits (88), Expect = 0.021 Identities = 74/283 (26%), Positives = 86/283 (30%), Gaps = 56/283 (19%) Query: 23 ESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASA----GAPAA 78 E G G AG P+ A ++ +K G +G AA G P Sbjct: 716 EVGPAGPNGFAG--PAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGP 773 Query: 79 MLSDTDAGD----AFASAAAVAKPGPPDGRKG-----SPCGEEEL--------PSAAAAA 121 S D G F AA P P G G P G+E L P Sbjct: 774 AGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGE 833 Query: 122 AAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSL----------FPYQAAAGA 171 A + +PGPQG L AP L P A A Sbjct: 834 VGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGL-LGAPGILGLPGSRGERGLPGVAGAVG 892 Query: 172 PHGPVYPA-PNGARYPYGSMLPPG-----------GFPAAVCPPGRAQFGPGAGAGSGAG 219 GP+ A P GAR P G++ PG G P PPGR G Sbjct: 893 EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGR----------DGQP 942 Query: 220 GSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPG 262 G G G PG A GP+ AG G G G G Sbjct: 943 GHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSG 985 Score = 34.3 bits (77), Expect = 0.39 Identities = 49/191 (25%), Positives = 60/191 (31%), Gaps = 27/191 (14%) Query: 94 AVAKPGP-----PDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQS 148 A PGP P G G P + P+ A A A ER + Sbjct: 104 AAGAPGPQGFQGPAGEPGEP--GQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVV-- 159 Query: 149 PGPQGSE-------LAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVC 201 GPQG+ L + + G P P G G PG A Sbjct: 160 -GPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGL 218 Query: 202 PPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPG----------AAAAGS 251 P R + G AG+ S G GP S G P + PG A AG Sbjct: 219 PGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGP 278 Query: 252 CGGLGGLGVPG 262 G G +G+PG Sbjct: 279 AGPRGEVGLPG 289 Score = 31.6 bits (70), Expect = 2.6 Identities = 32/116 (27%), Positives = 37/116 (31%), Gaps = 10/116 (8%) Query: 149 PGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRA-- 206 PGP G + G P P P P G + + G P G Sbjct: 47 PGPPGRD--------GEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGP 98 Query: 207 QFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPG 262 + PGA G G G G PG + A GP AG G G G PG Sbjct: 99 RGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPG 154 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 58.9 bits (141), Expect = 1e-08 Identities = 79/279 (28%), Positives = 92/279 (32%), Gaps = 68/279 (24%) Query: 28 GSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAA-ASAGAPAAMLSDTDAG 86 G GG G + P PQ L + G GEP AGAP A DAG Sbjct: 624 GPGGDKGD--TGPPGPQGL---QGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAG 678 Query: 87 DAFASAAAVAKPGPPDGRKGSPC----GEEELPSAAAAAAAAAAAAAATARYSMDSLSSE 142 A + GPP G G+P P AA A + + E Sbjct: 679 -------APGERGPP-GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE 730 Query: 143 RYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPG-------- 194 R L SPGP+G + G P P +G R P G + PPG Sbjct: 731 RGGLGSPGPKGDK-----------GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK 779 Query: 195 ------GFPAAVCPPG----RAQFGPGAGAG----------------SGAGGSSGGGGGP 228 G P P G R + GP AG GA G G GG P Sbjct: 780 GEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP 839 Query: 229 GTYQYSQGAPLYGPYPGAAAA----GSCGGLGGLGVPGS 263 G G+ GP PG GS GG G G PG+ Sbjct: 840 GVAGPPGGSGPAGP-PGPQGVKGERGSPGGPGAAGFPGA 877 Score = 56.2 bits (134), Expect = 1e-07 Identities = 72/256 (28%), Positives = 85/256 (33%), Gaps = 51/256 (19%) Query: 14 LPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASA 73 LPG E R G+ GS G LP SP K + +GS G P Sbjct: 1000 LPGLAGTAGEPGRDGNPGSDG-LPGRDGSPG----GKGDRGENGSPGAPGAPGHPGPPGP 1054 Query: 74 GAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATAR 133 PA D A A PGP G +G+P + AA Sbjct: 1055 VGPAGKSGDRGESGPAGPAGA---PGPA-GSRGAPGPQGPRGDKGETGERGAAG------ 1104 Query: 134 YSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPP 193 + R + +PG GS A Q A G+P P G R P G PP Sbjct: 1105 -----IKGHRGFPGNPGAPGSPGPAG-----QQGAIGSP------GPAGPRGPVGPSGPP 1148 Query: 194 G-----GFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAA 248 G G P + PPG G GS G G PG Q P P P A Sbjct: 1149 GKDGTSGHPGPIGPPGPR-------GNRGERGSEGSPGHPG-----QPGP---PGPPGAP 1193 Query: 249 AGSCGGLGGLGVPGSG 264 CGG+G + G G Sbjct: 1194 GPCCGGVGAAAIAGIG 1209 Score = 55.5 bits (132), Expect = 2e-07 Identities = 71/252 (28%), Positives = 88/252 (34%), Gaps = 30/252 (11%) Query: 30 GGSAGHL-PSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLSDTDAGDA 88 GG AG+ P+ P P GS + GEP A P A Sbjct: 167 GGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPG------PPGA 220 Query: 89 FASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAA--AATARYSMDSLSSERYYL 146 + K G GR G P GE LP A D + E+ Sbjct: 221 IGPSGPAGKDGE-SGRPGRP-GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGET 278 Query: 147 QSPGPQGS-----ELAAPCSLFPYQAAAGAPHGPVYPAPNGARYPYGSMLPPGGFPAAVC 201 +PG +G E AP + P + A G P P GAR G+ G P Sbjct: 279 GAPGLKGENGLPGENGAPGPMGP-RGAPGERGRPGLPGAAGARGNDGAR-GSDGQPGPPG 336 Query: 202 PPGRAQF--GPGAGAGSGAGGSSGGGGGPGT--------YQYSQGAPLYGPYPGAAAAGS 251 PPG A F PGA G GS G G PG + +QG P GP + G Sbjct: 337 PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPP--GPPGINGSPGG 394 Query: 252 CGGLGGLGVPGS 263 G +G G+PG+ Sbjct: 395 KGEMGPAGIPGA 406 Score = 54.7 bits (130), Expect = 3e-07 Identities = 78/288 (27%), Positives = 91/288 (31%), Gaps = 57/288 (19%) Query: 14 LPGAHFYPLESARGGSGGSAGH--LPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPA-A 70 +PG E + GS G G LP AA ++ + F G + GE A Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGLPGAAG-------ERGAPGFRGPAGPNGIPGEKGPA 506 Query: 71 ASAGAPAAMLSDTDAGDAFASAAA--------VAKPGPP--DGRKGSPCGEEEL------ 114 GAP AG+ PG P DG+ G P + E Sbjct: 507 GERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPP 566 Query: 115 -PSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPH 173 PS + ER PGPQG P + P Sbjct: 567 GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP---------PGKNGETGPQ 617 Query: 174 GPVYPAPNGARYPYGSMLPPG-----GFPAAVCPPGR----AQFGPGAGAGS-GAGGSSG 223 GP P P G G PPG G P PPG + GP AG+ GA G G Sbjct: 618 GP--PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG 675 Query: 224 GGGGPGTYQ---------YSQGAPLYGPYPGAAAAGSCGGLGGLGVPG 262 G PG GA GP G AAG G G G PG Sbjct: 676 DAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPG 723 Score = 48.5 bits (114), Expect = 2e-05 Identities = 70/259 (27%), Positives = 87/259 (33%), Gaps = 28/259 (10%) Query: 21 PLESARGGSGGSAGHL----PSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASA--- 73 P E GG G AG P+ P PQ + ++ S G+ G P + Sbjct: 830 PGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGN 889 Query: 74 ----GAPAAMLSDTDAGDAFASAAAVAKPGP--PDGRKGSPCGEEELPSAAAAAAAAA-- 125 G + D G A + A PG P G G P GE+ P A A Sbjct: 890 PGPPGPSGSPGKDGPPGPA-GNTGAPGSPGVSGPKGDAGQP-GEKGSPGAQGPPGAPGPL 947 Query: 126 AAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARY 185 A T + SPGPQG + S P GP P P G Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKGE---SGKPGANGLSGERGP--PGPQGLPG 1002 Query: 186 PYGSMLPPG--GFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQGAPLYGPY 243 G+ PG G P + PGR G+ G G G +G G PG + GP Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGR----DGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPA 1058 Query: 244 PGAAAAGSCGGLGGLGVPG 262 + G G G G PG Sbjct: 1059 GKSGDRGESGPAGPAGAPG 1077 Score = 47.0 bits (110), Expect = 6e-05 Identities = 65/212 (30%), Positives = 75/212 (35%), Gaps = 56/212 (26%) Query: 66 GEPAAASA-GAPAAMLSDTDAGDAFASAAAVAKPGPPD--GRKGSPCGEEELPSAAAAAA 122 G P AA A G A SD G PGPP G GSP + E+ A + + Sbjct: 312 GLPGAAGARGNDGARGSDGQPGP----------PGPPGTAGFPGSPGAKGEVGPAGSPGS 361 Query: 123 AAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNG 182 A PGPQG A A P GP P NG Sbjct: 362 NGAPGQRG-----------------EPGPQG------------HAGAQGPPGP--PGING 390 Query: 183 ARYPYGSMLPPG-----GFPAAVCPPGRA--QFGPGAGAGSGAGGSSGGGGGPGTYQYSQ 235 + G M P G G A PPG A PG G+G G +G G PG Sbjct: 391 SPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERG 450 Query: 236 GAPLYGPYPGAAAA----GSCGGLGGLGVPGS 263 A + G PGA GS G G G+PG+ Sbjct: 451 EAGIPG-VPGAKGEDGKDGSPGEPGANGLPGA 481 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/100 (36%), Positives = 42/100 (42%), Gaps = 14/100 (14%) Query: 172 PHGPVYPAPNGARYPYGSMLPPG--GFPAAVCPPGRAQFGPGAGAGSGAGGSSGGGG--- 226 P GP P P G + GS PG GFP A PG PG+ G G SG G Sbjct: 850 PAGP--PGPQGVKGERGSPGGPGAAGFPGARGLPGP----PGSNGNPGPPGPSGSPGKDG 903 Query: 227 --GPGTYQYSQGAP-LYGPYPGAAAAGSCGGLGGLGVPGS 263 GP + G+P + GP A G G G G PG+ Sbjct: 904 PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA 943 Score = 39.7 bits (91), Expect = 0.009 Identities = 76/292 (26%), Positives = 89/292 (30%), Gaps = 54/292 (18%) Query: 9 VSSVNLPGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEP 68 V PG++ P + G G AG P P ++ K G + + G P Sbjct: 353 VGPAGSPGSNGAPGQRGEPGPQGHAG--AQGPPGPPGINGSPGGK---GEMGPAGIPGAP 407 Query: 69 AAASAGAPAAMLSDTDAGDAFASAA------AVAKPGP-----------------PDGRK 105 A P A A A +PGP DG+ Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467 Query: 106 GSPC--GEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLF 163 GSP G LP AA A A + + E+ GP G E AP Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPA----GPNGIPGEK------GPAG-ERGAPGPAG 516 Query: 164 PYQAAA-----GAPHGPVY---PAPNGARYPYGSMLPPG--GFPAAVCPPGRAQFGPGAG 213 P AA G P GP P G G PPG G PPG + GP Sbjct: 517 PRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS--GPRGQ 574 Query: 214 AG-SGAGGSSGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSG 264 G G G G G PG G GP G G G G G G Sbjct: 575 PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626 Score = 35.8 bits (81), Expect = 0.14 Identities = 67/273 (24%), Positives = 82/273 (30%), Gaps = 41/273 (15%) Query: 15 PGAHFYPLESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFS-------GSLSCEAVSGE 67 PG P + G G+ G S S K D + +K S G+ ++G Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI 952 Query: 68 PAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPP--DGRKGSPCGEEELPSAAAAAAAAA 125 A P M + KPG G +G P G + LP A A Sbjct: 953 TGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPP-GPQGLPGLAGTAGEPG 1011 Query: 126 AAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPVYPAPNGARY 185 D L SPG +G + GAP P +P P G Sbjct: 1012 R----DGNPGSDGLPGRD---GSPGGKGDR--------GENGSPGAPGAPGHPGPPGPVG 1056 Query: 186 PYGSM-----LPPGGFPAAVCPPG-RAQFGP----------GAGAGSGAGGSSGGGGGPG 229 P G P G A P G R GP G +G G G G PG Sbjct: 1057 PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPG 1116 Query: 230 TYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPG 262 A G AG G +G G PG Sbjct: 1117 APGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPG 1149 Score = 33.1 bits (74), Expect = 0.88 Identities = 37/122 (30%), Positives = 40/122 (32%), Gaps = 26/122 (21%) Query: 155 ELAAPCSLFPY-QAAAGAPHGPVYPA--PNGARYPYGSMLPPGGFPAAVCPPGRAQFGPG 211 EL P P+ + A P P P PNG + P G PG PPG PG Sbjct: 71 ELDCPNPEIPFGECCAVCPQPPTAPTRPPNG-QGPQGPKGDPG-------PPGI----PG 118 Query: 212 AGAGSGAGGSSGGGGGP-----------GTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGV 260 G G G G P G YS Y G A G G G G Sbjct: 119 RNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGP 178 Query: 261 PG 262 PG Sbjct: 179 PG 180 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.131 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,718,950 Number of Sequences: 37866 Number of extensions: 2062991 Number of successful extensions: 23288 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 386 Number of HSP's successfully gapped in prelim test: 933 Number of HSP's that attempted gapping in prelim test: 10947 Number of HSP's gapped (non-prelim): 6578 length of query: 686 length of database: 18,247,518 effective HSP length: 109 effective length of query: 577 effective length of database: 14,120,124 effective search space: 8147311548 effective search space used: 8147311548 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.