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Search of human proteins with 22538446
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22538446 tumor protein p53 inducible protein 3 [Homo
sapiens]
(332 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens] 667 0.0
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens] 667 0.0
gi|18379349 vesicle amine transport protein 1 [Homo sapiens] 140 2e-33
gi|24308257 vesicle amine transport protein 1 homolog (T. califo... 130 2e-30
gi|28557745 zinc binding alcohol dehydrogenase domain containing... 115 7e-26
gi|194239674 crystallin, zeta isoform a [Homo sapiens] 114 9e-26
gi|13236495 crystallin, zeta isoform a [Homo sapiens] 114 9e-26
gi|41872631 fatty acid synthase [Homo sapiens] 106 3e-23
gi|194239676 crystallin, zeta isoform b [Homo sapiens] 90 3e-18
gi|197927207 crystallin, zeta isoform c [Homo sapiens] 69 8e-12
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa... 67 3e-11
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a... 62 9e-10
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens] 60 2e-09
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens] 60 2e-09
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens] 60 2e-09
gi|90669511 crystallin, zeta-like 1 [Homo sapiens] 60 2e-09
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b... 58 1e-08
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s... 45 1e-04
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap... 41 0.002
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa... 37 0.019
gi|156627571 sorbitol dehydrogenase [Homo sapiens] 37 0.019
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa... 37 0.024
gi|226246682 prostaglandin reductase 2 [Homo sapiens] 36 0.055
gi|226246680 prostaglandin reductase 2 [Homo sapiens] 36 0.055
gi|22748929 prostaglandin reductase 2 [Homo sapiens] 36 0.055
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa... 36 0.055
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 35 0.12
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens] 33 0.35
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens] 33 0.35
gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens] 32 1.0
>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 667 bits (1721), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60
MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI
Sbjct: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60
Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120
LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA
Sbjct: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120
Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180
IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM
Sbjct: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180
Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240
AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL
Sbjct: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240
Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300
MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV
Sbjct: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300
Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332
LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
Sbjct: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332
>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 667 bits (1721), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60
MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI
Sbjct: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60
Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120
LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA
Sbjct: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120
Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180
IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM
Sbjct: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180
Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240
AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL
Sbjct: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240
Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300
MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV
Sbjct: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300
Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332
LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
Sbjct: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332
>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
Length = 393
Score = 140 bits (353), Expect = 2e-33
Identities = 100/325 (30%), Positives = 158/325 (48%), Gaps = 14/325 (4%)
Query: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74
L + A P+PG G++ L++ A LN ADLM RQG YD P G+E +G V +G
Sbjct: 64 LQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGE 123
Query: 75 GCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHL 134
G K GD M L G + VTVP IPE +T +AAA+ ++TA+ +L
Sbjct: 124 GVSDR-KAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFD 182
Query: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK 194
GN+Q G VL+H GVG AA+QL R + + S K + ++ G +Y
Sbjct: 183 FGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDYHT 242
Query: 195 EDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDINGPLF 251
D+ + K + GV++++D +GGS K N L G+ V YG L+ G N
Sbjct: 243 TDYVDEIKKISP-KGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMAL 301
Query: 252 SKLLFKRGSLITSLLRSRDNK--------YKQMLVNAFTEQILPHFSTEGPQRLLPVLDR 303
++ + + S +T+L + N+ Y V + + + + P +D
Sbjct: 302 ARTWWNQFS-VTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDS 360
Query: 304 IYPVTEIQEAHKYMEANKNIGKIVL 328
++P ++ +A K M+ KN+GK++L
Sbjct: 361 VWPFEKVADAMKQMQEKKNVGKVLL 385
>gi|24308257 vesicle amine transport protein 1 homolog (T.
californica)-like [Homo sapiens]
Length = 419
Score = 130 bits (326), Expect = 2e-30
Identities = 96/337 (28%), Positives = 165/337 (48%), Gaps = 23/337 (6%)
Query: 10 GGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHV 69
GG L + A P P +GE+ ++V A LN DLM RQG D PP + G E SG V
Sbjct: 51 GGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIV 110
Query: 70 AELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAF 129
LG +G+ +IGD MA + A+ V P + IP+ ++ ++AAA P ++TA+
Sbjct: 111 EALGDSVKGY-EIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAY 169
Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189
+L V N++ G VL+H+ GVG A QL +P VT E + +
Sbjct: 170 VMLFEVANLREGMSVLVHSAGGGVGQAVAQL---CSTVPNVTVFGTASTFKHEAIKDSVT 226
Query: 190 FNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDI 246
+ + +K GV+++LDC+ G K ++ L G ++LYG ++ G
Sbjct: 227 HLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETK 286
Query: 247 NGPLFSK-----------LLFKRGSLIT--SLLRSRDNKYKQMLVNAFTEQILPHFSTEG 293
+ F+K L++ +I SLL + + L+ E+++ ++
Sbjct: 287 SFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYN--- 343
Query: 294 PQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330
+++ PV+D ++ + E++EA + + NIGK++L++
Sbjct: 344 QKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDV 380
>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
[Homo sapiens]
Length = 377
Score = 115 bits (287), Expect = 7e-26
Identities = 93/321 (28%), Positives = 142/321 (44%), Gaps = 20/321 (6%)
Query: 23 PSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKI 82
P PG+G++L++ +N +D+ G+YDP +G E G V LG + +
Sbjct: 58 PLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASARYTV 117
Query: 83 GDTAMALLPGGGQAQYVTVPEGLLMPI----PEGLTLTQAAAIPEAWLTAFQLLHLVGNV 138
G A+A + G A+Y VP + P+ PE LTL + TA+ L +G +
Sbjct: 118 GQ-AVAYMAPGSFAEYTVVPASIATPVPSVKPEYLTLLVSGT------TAYISLKELGGL 170
Query: 139 QAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFS 198
G VL+ A G G A+QL++ A + T S +K + LG NYK E
Sbjct: 171 SEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYKTEPVG 230
Query: 199 EATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDI--------NGPL 250
LK GV+++ + +GG+ ++ V+ LA GR ++ G + G G L
Sbjct: 231 -TVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSPVKAGTL 289
Query: 251 FSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEI 310
+KLL K S+ L +KY+ + + + E L R + I
Sbjct: 290 PAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESI 349
Query: 311 QEAHKYMEANKNIGKIVLELP 331
A YM KN GKIV+ELP
Sbjct: 350 FRAVNYMYMGKNTGKIVVELP 370
>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 114 bits (286), Expect = 9e-26
Identities = 91/332 (27%), Positives = 157/332 (47%), Gaps = 12/332 (3%)
Query: 1 MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59
M AV + GGPE L ++ ++A P P + +VL+KV A +N + R G Y P
Sbjct: 8 MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67
Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119
G + +G + +G K + GG A+Y + + +PE L Q A
Sbjct: 68 TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127
Query: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179
AI + TA++ L V+AG+ VL+H GVG AA Q+ R G L TAG+++ +
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187
Query: 180 MAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG 239
+ + GA FN+++ ++ + K+ G+++I++ + K+++ L+ GR ++ G
Sbjct: 188 IVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVG 247
Query: 240 LMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLP 299
G +IN + K S+I L S + Q A + + L P
Sbjct: 248 SRGTIEINP---RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKP 297
Query: 300 VLDRIYPVTEIQEAHK-YMEANKNIGKIVLEL 330
V+ YP+ ++ EAH+ + + GK++L L
Sbjct: 298 VIGSQYPLEKVAEAHENIIHGSGATGKMILLL 329
>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 114 bits (286), Expect = 9e-26
Identities = 91/332 (27%), Positives = 157/332 (47%), Gaps = 12/332 (3%)
Query: 1 MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59
M AV + GGPE L ++ ++A P P + +VL+KV A +N + R G Y P
Sbjct: 8 MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67
Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119
G + +G + +G K + GG A+Y + + +PE L Q A
Sbjct: 68 TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127
Query: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179
AI + TA++ L V+AG+ VL+H GVG AA Q+ R G L TAG+++ +
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187
Query: 180 MAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG 239
+ + GA FN+++ ++ + K+ G+++I++ + K+++ L+ GR ++ G
Sbjct: 188 IVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVG 247
Query: 240 LMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLP 299
G +IN + K S+I L S + Q A + + L P
Sbjct: 248 SRGTIEINP---RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKP 297
Query: 300 VLDRIYPVTEIQEAHK-YMEANKNIGKIVLEL 330
V+ YP+ ++ EAH+ + + GK++L L
Sbjct: 298 VIGSQYPLEKVAEAHENIIHGSGATGKMILLL 329
>gi|41872631 fatty acid synthase [Homo sapiens]
Length = 2511
Score = 106 bits (264), Expect = 3e-23
Identities = 88/318 (27%), Positives = 147/318 (46%), Gaps = 36/318 (11%)
Query: 28 GEVLLKVAASALNRADLMQRQGQYDPP--PGA----SNILGLEASGHVAELGPGCQGHWK 81
G L V ++LN D+M G+ P PG ++LG+E SG A
Sbjct: 1560 GAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDAS---------- 1609
Query: 82 IGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAG 141
G M L+P G A V + L +P TL +AA++P + TA+ L + G V+ G
Sbjct: 1610 -GKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPG 1668
Query: 142 DYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE----KLGAAAGFNYKKEDF 197
+ +LIH+G GVG AAI + G T GS +K + +L + + N + F
Sbjct: 1669 ETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSF 1728
Query: 198 SEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDINGPLFSKL 254
+ L T G GV+L+L+ + + +V CLA GR++ G L + +F K
Sbjct: 1729 EQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKN 1788
Query: 255 LFKRGSLITSLLRSRDNKYKQM--LVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQE 312
+ G L+ + ++++ LV A +G R P+ ++ ++++
Sbjct: 1789 VTFHGVLLDAFFNESSADWREVWALVQAGIR--------DGVVR--PLKCTVFHGAQVED 1838
Query: 313 AHKYMEANKNIGKIVLEL 330
A +YM K+IGK+V+++
Sbjct: 1839 AFRYMAQGKHIGKVVVQV 1856
>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
Length = 295
Score = 89.7 bits (221), Expect = 3e-18
Identities = 61/198 (30%), Positives = 98/198 (49%), Gaps = 1/198 (0%)
Query: 1 MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59
M AV + GGPE L ++ ++A P P + +VL+KV A +N + R G Y P
Sbjct: 8 MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67
Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119
G + +G + +G K + GG A+Y + + +PE L Q A
Sbjct: 68 TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127
Query: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179
AI + TA++ L V+AG+ VL+H GVG AA Q+ R G L TAG+++ +
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187
Query: 180 MAEKLGAAAGFNYKKEDF 197
+ + GA FN+++ ++
Sbjct: 188 IVLQNGAHEVFNHREVNY 205
>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
Length = 192
Score = 68.6 bits (166), Expect = 8e-12
Identities = 54/202 (26%), Positives = 101/202 (50%), Gaps = 13/202 (6%)
Query: 132 LHLVGN--VQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189
+HL+ + V+AG+ VL+H GVG AA Q+ R G L TAG+++ ++ + GA
Sbjct: 1 MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 60
Query: 190 FNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGP 249
FN+++ ++ + K+ G+++I++ + K+++ L+ GR ++ G G +IN
Sbjct: 61 FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP- 119
Query: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309
+ K S+I L S + Q A + + L PV+ YP+ +
Sbjct: 120 --RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKPVIGSQYPLEK 170
Query: 310 IQEAHK-YMEANKNIGKIVLEL 330
+ EAH+ + + GK++L L
Sbjct: 171 VAEAHENIIHGSGATGKMILLL 192
>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
sapiens]
Length = 396
Score = 66.6 bits (161), Expect = 3e-11
Identities = 69/218 (31%), Positives = 101/218 (46%), Gaps = 36/218 (16%)
Query: 29 EVLLKVAASALNRADLMQRQGQYDPPPGASNI-------------------LGLEASGHV 69
EV++KV A+++N D+ R G GA+ + LG + SG V
Sbjct: 73 EVIVKVHAASVNPIDVNMRSGY-----GATALNMKRDPLHVKIKGEEFPLTLGRDVSGVV 127
Query: 70 AELGPGCQGHWKIGDTAMALLPG---GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWL 126
E G + ++K GD A +P G +++V V + P+ LT TQAA++P L
Sbjct: 128 MECGLDVK-YFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVAL 186
Query: 127 TAFQLLHLVGNVQ----AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182
TA+ ++ VG + G VLI GVGT AIQ+ + A + SQ ++
Sbjct: 187 TAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMK-AWDAHVTAVCSQDASELVR 245
Query: 183 KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
KLGA +YK E LK K + ILD +GGS
Sbjct: 246 KLGADDVIDYKSGSVEE-QLKSLK--PFDFILDNVGGS 280
>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
[Homo sapiens]
Length = 373
Score = 61.6 bits (148), Expect = 9e-10
Identities = 64/234 (27%), Positives = 103/234 (44%), Gaps = 7/234 (2%)
Query: 29 EVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMA 88
+V +K+ A+ +N +D+ QG Y P + G E V +G G K GD +
Sbjct: 72 DVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTG-LKPGDWVIP 130
Query: 89 LLPGGGQAQYVTV-PEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147
G G + V E L+ +P + L AA + TA+++L +Q GD V+ +
Sbjct: 131 ANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQN 190
Query: 148 AGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKL-GAAAGFNYKKEDFSEATLK-- 203
A SGVG A IQ+ G + + +Q ++++L A +E+ +K
Sbjct: 191 ASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNF 250
Query: 204 FTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK 257
F L L+C+GG + + LA G V YG M + + S L+FK
Sbjct: 251 FKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASV-SLLIFK 303
>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 60.5 bits (145), Expect = 2e-09
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
Query: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160
E LL P+ + L+ A + LTA F LL + G V+ G+ V+++A VG+ Q+
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161
Query: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
++ G + GS +K+ +KLG FNYK + E TLK G + D +GG
Sbjct: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221
Query: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250
+ + + GR + G + + GPL
Sbjct: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251
>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 60.5 bits (145), Expect = 2e-09
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
Query: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160
E LL P+ + L+ A + LTA F LL + G V+ G+ V+++A VG+ Q+
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161
Query: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
++ G + GS +K+ +KLG FNYK + E TLK G + D +GG
Sbjct: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221
Query: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250
+ + + GR + G + + GPL
Sbjct: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251
>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
Length = 301
Score = 60.5 bits (145), Expect = 2e-09
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
Query: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160
E LL P+ + L+ A + LTA F LL + G V+ G+ V+++A VG+ Q+
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161
Query: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
++ G + GS +K+ +KLG FNYK + E TLK G + D +GG
Sbjct: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221
Query: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250
+ + + GR + G + + GPL
Sbjct: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251
>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
Length = 349
Score = 60.5 bits (145), Expect = 2e-09
Identities = 60/204 (29%), Positives = 96/204 (47%), Gaps = 17/204 (8%)
Query: 23 PSPGEGEVLLKVAASALNRAD---LMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGH 79
P + V L+V A AL++ + L + + + D P +G E +G V ++G
Sbjct: 26 PVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFP-----VGREIAGIVLDVGSKVS-F 79
Query: 80 WKIGDTAMALLP----GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLV 135
++ D + +LP G + V V E L+ PE +T T+AA + A+ LH +
Sbjct: 80 FQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYL 139
Query: 136 GNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEK----LGAAAGFN 191
++ G VLI G S GT AIQL GA + TA S + Q E+ + +
Sbjct: 140 SHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVS 199
Query: 192 YKKEDFSEATLKFTKGAGVNLILD 215
K +E+ L+ T G GV+++LD
Sbjct: 200 NGKVHVAESCLEETGGLGVDIVLD 223
>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
[Homo sapiens]
Length = 297
Score = 57.8 bits (138), Expect = 1e-08
Identities = 62/227 (27%), Positives = 98/227 (43%), Gaps = 7/227 (3%)
Query: 36 ASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQ 95
A+ +N +D+ QG Y P + G E V +G G K GD + G G
Sbjct: 3 AAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTG-LKPGDWVIPANAGLGT 61
Query: 96 AQYVTV-PEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154
+ V E L+ +P + L AA + TA+++L +Q GD V+ +A SGVG
Sbjct: 62 WRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVG 121
Query: 155 TAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKL-GAAAGFNYKKEDFSEATLK--FTKGAGV 210
A IQ+ G + + +Q ++++L A +E+ +K F
Sbjct: 122 QAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQP 181
Query: 211 NLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK 257
L L+C+GG + + LA G V YG M + + S L+FK
Sbjct: 182 RLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASV-SLLIFK 227
>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
sapiens]
Length = 374
Score = 44.7 bits (104), Expect = 1e-04
Identities = 63/259 (24%), Positives = 99/259 (38%), Gaps = 63/259 (24%)
Query: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74
L ++E+ P EV +K+ A+A+ D G DP ILG E +G V +G
Sbjct: 20 LSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGA-DPEGCFPVILGHEGAGIVESVGE 78
Query: 75 GCQGHWKIGDTAMAL-LPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQ--- 130
G K GDT + L +P G+ ++ P+ L + + +TQ + + F
Sbjct: 79 GVT-KLKAGDTVIPLYIPQCGECKFCLNPKTNLC---QKIRVTQGKGLMPDGTSRFTCKG 134
Query: 131 --LLHLVGNVQAGDYVLIHA---------------------------------------- 148
+LH +G +Y ++
Sbjct: 135 KTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSV 194
Query: 149 ----GLSGVGTAAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFNYKKEDFS----E 199
GL GVG A I ++AGA ++ K K A++ GA N +DFS E
Sbjct: 195 CAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECIN--PQDFSKPIQE 252
Query: 200 ATLKFTKGAGVNLILDCIG 218
++ T G GV+ +CIG
Sbjct: 253 VLIEMTDG-GVDYSFECIG 270
>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
sapiens]
Length = 380
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 5/128 (3%)
Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155
+QY V + L I + L + + + T + V G + GL GVG
Sbjct: 153 SQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF-GLGGVGL 211
Query: 156 AAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYK--KEDFSEATLKFTKGAGVNL 212
+A+ + AGA ++ + +K A+ LGA N + + E ++ TKG GV+
Sbjct: 212 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVDF 270
Query: 213 ILDCIGGS 220
LDC GGS
Sbjct: 271 ALDCAGGS 278
>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
sapiens]
Length = 375
Score = 37.4 bits (85), Expect = 0.019
Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155
+QY V E + I L + I + T + V V G + GL GVG
Sbjct: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206
Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211
+AI + AGA ++ K K A++LGA N YKK + LK GV+
Sbjct: 207 SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
Query: 212 LILDCIG 218
+ IG
Sbjct: 265 FSFEVIG 271
>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
Length = 357
Score = 37.4 bits (85), Expect = 0.019
Identities = 61/267 (22%), Positives = 100/267 (37%), Gaps = 44/267 (16%)
Query: 11 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADL----MQRQGQYDPPPGASNILGLEAS 66
GP +L ++ P PG EVLL++ + + +D+ R G + +LG EAS
Sbjct: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVK--KPMVLGHEAS 73
Query: 67 GHVAELGPGCQGHWKIGDTAMALLPG-----------------------------GGQAQ 97
G V ++G + H K GD +A+ PG G +
Sbjct: 74 GTVEKVGSSVK-HLKPGD-RVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131
Query: 98 YVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157
+ +P+ +T + A I + G V G VL+ G +G
Sbjct: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLV-CGAGPIGMVT 188
Query: 158 IQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKF--TKGAGVNLIL 214
+ + + GA +VT S +L A+++GA KE E K G + +
Sbjct: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248
Query: 215 DCIGG-SYWEKNVNCLALDGRWVLYGL 240
+C G + + + G VL GL
Sbjct: 249 ECTGAEASIQAGIYATRSGGNLVLVGL 275
>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
sapiens]
Length = 375
Score = 37.0 bits (84), Expect = 0.024
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155
+QY V E + I L + I + T + V V G + GL GVG
Sbjct: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206
Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211
+A+ + AGA ++ K K A++LGA N YKK + LK GV+
Sbjct: 207 SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
Query: 212 LILDCIG 218
+ IG
Sbjct: 265 FSFEVIG 271
>gi|226246682 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 35.8 bits (81), Expect = 0.055
Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 5/124 (4%)
Query: 120 AIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGV-GTAAIQLTRMAGAIPLV-TAGSQK 176
AI LT+ + G++ AG + ++ +G +G G+ A Q+ G +V G+ +
Sbjct: 132 AIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHE 191
Query: 177 K-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235
K + + +LG A NYKK++ +E L+ + AGV++ D +GG+ + ++ + +
Sbjct: 192 KCILLTSELGFDAAINYKKDNVAE-QLRESCPAGVDVYFDNVGGNISDTVISQMNENSHI 250
Query: 236 VLYG 239
+L G
Sbjct: 251 ILCG 254
>gi|226246680 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 35.8 bits (81), Expect = 0.055
Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 5/124 (4%)
Query: 120 AIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGV-GTAAIQLTRMAGAIPLV-TAGSQK 176
AI LT+ + G++ AG + ++ +G +G G+ A Q+ G +V G+ +
Sbjct: 132 AIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHE 191
Query: 177 K-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235
K + + +LG A NYKK++ +E L+ + AGV++ D +GG+ + ++ + +
Sbjct: 192 KCILLTSELGFDAAINYKKDNVAE-QLRESCPAGVDVYFDNVGGNISDTVISQMNENSHI 250
Query: 236 VLYG 239
+L G
Sbjct: 251 ILCG 254
>gi|22748929 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 35.8 bits (81), Expect = 0.055
Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 5/124 (4%)
Query: 120 AIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGV-GTAAIQLTRMAGAIPLV-TAGSQK 176
AI LT+ + G++ AG + ++ +G +G G+ A Q+ G +V G+ +
Sbjct: 132 AIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHE 191
Query: 177 K-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235
K + + +LG A NYKK++ +E L+ + AGV++ D +GG+ + ++ + +
Sbjct: 192 KCILLTSELGFDAAINYKKDNVAE-QLRESCPAGVDVYFDNVGGNISDTVISQMNENSHI 250
Query: 236 VLYG 239
+L G
Sbjct: 251 ILCG 254
>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
sapiens]
Length = 375
Score = 35.8 bits (81), Expect = 0.055
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 7/127 (5%)
Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155
+QY V E + I L + I + T + V V G + GL GVG
Sbjct: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF-GLGGVGL 206
Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211
+ + + AGA ++ K K A++LGA N YKK + LK GV+
Sbjct: 207 SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
Query: 212 LILDCIG 218
+ IG
Sbjct: 265 FSFEVIG 271
>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
Length = 1388
Score = 34.7 bits (78), Expect = 0.12
Identities = 26/115 (22%), Positives = 42/115 (36%), Gaps = 8/115 (6%)
Query: 27 EGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTA 86
E + AA+ ++ + + P G + + A GPG + T
Sbjct: 456 EDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTE 515
Query: 87 MALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAG 141
L+ GG+ P+G +P+P PE W+T Q H+ QAG
Sbjct: 516 EPLITAGGEESGSPPPDGPPLPLP--------TVAPERWITPAQREHVGMKGQAG 562
>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
Length = 375
Score = 33.1 bits (74), Expect = 0.35
Identities = 61/261 (23%), Positives = 93/261 (35%), Gaps = 56/261 (21%)
Query: 8 KPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASG 67
KPG P ++ EVA P E V +KV A+ L + M+ G ILG E +G
Sbjct: 17 KPGAPFSIEEVEVAPPKAKE--VRIKVVATGLCGTE-MKVLGSKHLDLLYPTILGHEGAG 73
Query: 68 HVAELGPGCQGHWKIGDTAMAL-LPGGGQA------------------------------ 96
V +G G K GD + L LP G+
Sbjct: 74 IVESIGEGVSTV-KPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFT 132
Query: 97 ----------------QYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQA 140
+Y + E + I L + I + T F V
Sbjct: 133 CKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTP 192
Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYK--KEDF 197
G + GL GVG + + + AGA ++ +++K + A++LGA N + K+
Sbjct: 193 GSTCAVF-GLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPI 251
Query: 198 SEATLKFTKGAGVNLILDCIG 218
E T AG++ + IG
Sbjct: 252 QEVLFDMT-DAGIDFCFEAIG 271
>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
Length = 368
Score = 33.1 bits (74), Expect = 0.35
Identities = 61/261 (23%), Positives = 93/261 (35%), Gaps = 56/261 (21%)
Query: 8 KPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASG 67
KPG P ++ EVA P E V +KV A+ L + M+ G ILG E +G
Sbjct: 17 KPGAPFSIEEVEVAPPKAKE--VRIKVVATGLCGTE-MKVLGSKHLDLLYPTILGHEGAG 73
Query: 68 HVAELGPGCQGHWKIGDTAMAL-LPGGGQA------------------------------ 96
V +G G K GD + L LP G+
Sbjct: 74 IVESIGEGVSTV-KPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFT 132
Query: 97 ----------------QYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQA 140
+Y + E + I L + I + T F V
Sbjct: 133 CKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTP 192
Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYK--KEDF 197
G + GL GVG + + + AGA ++ +++K + A++LGA N + K+
Sbjct: 193 GSTCAVF-GLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPI 251
Query: 198 SEATLKFTKGAGVNLILDCIG 218
E T AG++ + IG
Sbjct: 252 QEVLFDMT-DAGIDFCFEAIG 271
>gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]
Length = 880
Score = 31.6 bits (70), Expect = 1.0
Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 11/114 (9%)
Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61
LA + +PGGP + ++E+A+ SP LLKV A A + P PG+
Sbjct: 640 LAGQWPEPGGPYDKAIQELAQGSPS----LLKVDLEAWKAAPTGSPKPAVTPGPGS---- 691
Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMALLP--GGGQAQYVTVPEGLLMPIPEGL 113
L+ + GP + T M +P GG TV P P L
Sbjct: 692 -LKGKLGARQSGPRTKASLSAKGTHMRKVPPQGGQDCSASTVSASPEAPTPSPL 744
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,560,157
Number of Sequences: 37866
Number of extensions: 649337
Number of successful extensions: 1451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1401
Number of HSP's gapped (non-prelim): 52
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.