Guide to the Human Genome
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Search of human proteins with 22538446

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22538446 tumor protein p53 inducible protein 3 [Homo
sapiens]
         (332 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]      667   0.0  
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]      667   0.0  
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]          140   2e-33
gi|24308257 vesicle amine transport protein 1 homolog (T. califo...   130   2e-30
gi|28557745 zinc binding alcohol dehydrogenase domain containing...   115   7e-26
gi|194239674 crystallin, zeta isoform a [Homo sapiens]                114   9e-26
gi|13236495 crystallin, zeta isoform a [Homo sapiens]                 114   9e-26
gi|41872631 fatty acid synthase [Homo sapiens]                        106   3e-23
gi|194239676 crystallin, zeta isoform b [Homo sapiens]                 90   3e-18
gi|197927207 crystallin, zeta isoform c [Homo sapiens]                 69   8e-12
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa...    67   3e-11
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a...    62   9e-10
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]        60   2e-09
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]        60   2e-09
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]        60   2e-09
gi|90669511 crystallin, zeta-like 1 [Homo sapiens]                     60   2e-09
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b...    58   1e-08
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s...    45   1e-04
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap...    41   0.002
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa...    37   0.019
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                     37   0.019
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa...    37   0.024
gi|226246682 prostaglandin reductase 2 [Homo sapiens]                  36   0.055
gi|226246680 prostaglandin reductase 2 [Homo sapiens]                  36   0.055
gi|22748929 prostaglandin reductase 2 [Homo sapiens]                   36   0.055
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa...    36   0.055
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         35   0.12 
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]    33   0.35 
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]      33   0.35 
gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]             32   1.0  

>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score =  667 bits (1721), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60
           MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI
Sbjct: 1   MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60

Query: 61  LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120
           LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA
Sbjct: 61  LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120

Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180
           IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM
Sbjct: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180

Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240
           AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL
Sbjct: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240

Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300
           MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV
Sbjct: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300

Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332
           LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
Sbjct: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score =  667 bits (1721), Expect = 0.0
 Identities = 332/332 (100%), Positives = 332/332 (100%)

Query: 1   MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60
           MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI
Sbjct: 1   MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60

Query: 61  LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120
           LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA
Sbjct: 61  LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120

Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180
           IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM
Sbjct: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180

Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240
           AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL
Sbjct: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240

Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300
           MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV
Sbjct: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300

Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332
           LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
Sbjct: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score =  140 bits (353), Expect = 2e-33
 Identities = 100/325 (30%), Positives = 158/325 (48%), Gaps = 14/325 (4%)

Query: 15  LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74
           L  +  A P+PG G++ L++ A  LN ADLM RQG YD  P      G+E +G V  +G 
Sbjct: 64  LQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGE 123

Query: 75  GCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHL 134
           G     K GD  M L   G   + VTVP      IPE +T  +AAA+   ++TA+ +L  
Sbjct: 124 GVSDR-KAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFD 182

Query: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK 194
            GN+Q G  VL+H    GVG AA+QL R    + +    S  K +  ++ G     +Y  
Sbjct: 183 FGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDYHT 242

Query: 195 EDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDINGPLF 251
            D+ +   K +   GV++++D +GGS   K  N L   G+ V YG   L+ G   N    
Sbjct: 243 TDYVDEIKKISP-KGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMAL 301

Query: 252 SKLLFKRGSLITSLLRSRDNK--------YKQMLVNAFTEQILPHFSTEGPQRLLPVLDR 303
           ++  + + S +T+L   + N+        Y    V   +  +    +      + P +D 
Sbjct: 302 ARTWWNQFS-VTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDS 360

Query: 304 IYPVTEIQEAHKYMEANKNIGKIVL 328
           ++P  ++ +A K M+  KN+GK++L
Sbjct: 361 VWPFEKVADAMKQMQEKKNVGKVLL 385


>gi|24308257 vesicle amine transport protein 1 homolog (T.
           californica)-like [Homo sapiens]
          Length = 419

 Score =  130 bits (326), Expect = 2e-30
 Identities = 96/337 (28%), Positives = 165/337 (48%), Gaps = 23/337 (6%)

Query: 10  GGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHV 69
           GG   L +   A P P +GE+ ++V A  LN  DLM RQG  D PP    + G E SG V
Sbjct: 51  GGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIV 110

Query: 70  AELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAF 129
             LG   +G+ +IGD  MA +     A+ V  P   +  IP+ ++ ++AAA P  ++TA+
Sbjct: 111 EALGDSVKGY-EIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAY 169

Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189
            +L  V N++ G  VL+H+   GVG A  QL      +P VT          E +  +  
Sbjct: 170 VMLFEVANLREGMSVLVHSAGGGVGQAVAQL---CSTVPNVTVFGTASTFKHEAIKDSVT 226

Query: 190 FNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDI 246
             + +       +K     GV+++LDC+ G    K ++ L   G ++LYG   ++ G   
Sbjct: 227 HLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETK 286

Query: 247 NGPLFSK-----------LLFKRGSLIT--SLLRSRDNKYKQMLVNAFTEQILPHFSTEG 293
           +   F+K            L++   +I   SLL     + +  L+    E+++  ++   
Sbjct: 287 SFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYN--- 343

Query: 294 PQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330
            +++ PV+D ++ + E++EA + +    NIGK++L++
Sbjct: 344 QKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDV 380


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score =  115 bits (287), Expect = 7e-26
 Identities = 93/321 (28%), Positives = 142/321 (44%), Gaps = 20/321 (6%)

Query: 23  PSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKI 82
           P PG+G++L++     +N +D+    G+YDP       +G E  G V  LG      + +
Sbjct: 58  PLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASARYTV 117

Query: 83  GDTAMALLPGGGQAQYVTVPEGLLMPI----PEGLTLTQAAAIPEAWLTAFQLLHLVGNV 138
           G  A+A +  G  A+Y  VP  +  P+    PE LTL  +        TA+  L  +G +
Sbjct: 118 GQ-AVAYMAPGSFAEYTVVPASIATPVPSVKPEYLTLLVSGT------TAYISLKELGGL 170

Query: 139 QAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFS 198
             G  VL+ A   G G  A+QL++ A    + T  S +K    + LG     NYK E   
Sbjct: 171 SEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYKTEPVG 230

Query: 199 EATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDI--------NGPL 250
              LK     GV+++ + +GG+ ++  V+ LA  GR ++ G + G            G L
Sbjct: 231 -TVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSPVKAGTL 289

Query: 251 FSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEI 310
            +KLL K  S+    L    +KY+  + +     +      E     L    R   +  I
Sbjct: 290 PAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESI 349

Query: 311 QEAHKYMEANKNIGKIVLELP 331
             A  YM   KN GKIV+ELP
Sbjct: 350 FRAVNYMYMGKNTGKIVVELP 370


>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score =  114 bits (286), Expect = 9e-26
 Identities = 91/332 (27%), Positives = 157/332 (47%), Gaps = 12/332 (3%)

Query: 1   MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59
           M AV   + GGPE L ++ ++A P P + +VL+KV A  +N  +   R G Y   P    
Sbjct: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67

Query: 60  ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119
             G + +G +  +G       K      +    GG A+Y    +  +  +PE L   Q A
Sbjct: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127

Query: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179
           AI   + TA++ L     V+AG+ VL+H    GVG AA Q+ R  G   L TAG+++  +
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187

Query: 180 MAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG 239
           +  + GA   FN+++ ++ +   K+    G+++I++ +      K+++ L+  GR ++ G
Sbjct: 188 IVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVG 247

Query: 240 LMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLP 299
             G  +IN       + K  S+I   L S   +  Q    A    +   +       L P
Sbjct: 248 SRGTIEINP---RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKP 297

Query: 300 VLDRIYPVTEIQEAHK-YMEANKNIGKIVLEL 330
           V+   YP+ ++ EAH+  +  +   GK++L L
Sbjct: 298 VIGSQYPLEKVAEAHENIIHGSGATGKMILLL 329


>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score =  114 bits (286), Expect = 9e-26
 Identities = 91/332 (27%), Positives = 157/332 (47%), Gaps = 12/332 (3%)

Query: 1   MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59
           M AV   + GGPE L ++ ++A P P + +VL+KV A  +N  +   R G Y   P    
Sbjct: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67

Query: 60  ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119
             G + +G +  +G       K      +    GG A+Y    +  +  +PE L   Q A
Sbjct: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127

Query: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179
           AI   + TA++ L     V+AG+ VL+H    GVG AA Q+ R  G   L TAG+++  +
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187

Query: 180 MAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG 239
           +  + GA   FN+++ ++ +   K+    G+++I++ +      K+++ L+  GR ++ G
Sbjct: 188 IVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVG 247

Query: 240 LMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLP 299
             G  +IN       + K  S+I   L S   +  Q    A    +   +       L P
Sbjct: 248 SRGTIEINP---RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKP 297

Query: 300 VLDRIYPVTEIQEAHK-YMEANKNIGKIVLEL 330
           V+   YP+ ++ EAH+  +  +   GK++L L
Sbjct: 298 VIGSQYPLEKVAEAHENIIHGSGATGKMILLL 329


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score =  106 bits (264), Expect = 3e-23
 Identities = 88/318 (27%), Positives = 147/318 (46%), Gaps = 36/318 (11%)

Query: 28   GEVLLKVAASALNRADLMQRQGQYDPP--PGA----SNILGLEASGHVAELGPGCQGHWK 81
            G  L  V  ++LN  D+M   G+  P   PG      ++LG+E SG  A           
Sbjct: 1560 GAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDAS---------- 1609

Query: 82   IGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAG 141
             G   M L+P  G A  V +    L  +P   TL +AA++P  + TA+  L + G V+ G
Sbjct: 1610 -GKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPG 1668

Query: 142  DYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE----KLGAAAGFNYKKEDF 197
            + +LIH+G  GVG AAI +    G     T GS +K    +    +L + +  N +   F
Sbjct: 1669 ETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSF 1728

Query: 198  SEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDINGPLFSKL 254
             +  L  T G GV+L+L+ +     + +V CLA  GR++  G   L     +   +F K 
Sbjct: 1729 EQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKN 1788

Query: 255  LFKRGSLITSLLRSRDNKYKQM--LVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQE 312
            +   G L+ +        ++++  LV A           +G  R  P+   ++   ++++
Sbjct: 1789 VTFHGVLLDAFFNESSADWREVWALVQAGIR--------DGVVR--PLKCTVFHGAQVED 1838

Query: 313  AHKYMEANKNIGKIVLEL 330
            A +YM   K+IGK+V+++
Sbjct: 1839 AFRYMAQGKHIGKVVVQV 1856


>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
          Length = 295

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 61/198 (30%), Positives = 98/198 (49%), Gaps = 1/198 (0%)

Query: 1   MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59
           M AV   + GGPE L ++ ++A P P + +VL+KV A  +N  +   R G Y   P    
Sbjct: 8   MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 67

Query: 60  ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119
             G + +G +  +G       K      +    GG A+Y    +  +  +PE L   Q A
Sbjct: 68  TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 127

Query: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179
           AI   + TA++ L     V+AG+ VL+H    GVG AA Q+ R  G   L TAG+++  +
Sbjct: 128 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 187

Query: 180 MAEKLGAAAGFNYKKEDF 197
           +  + GA   FN+++ ++
Sbjct: 188 IVLQNGAHEVFNHREVNY 205


>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
          Length = 192

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 54/202 (26%), Positives = 101/202 (50%), Gaps = 13/202 (6%)

Query: 132 LHLVGN--VQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189
           +HL+ +  V+AG+ VL+H    GVG AA Q+ R  G   L TAG+++  ++  + GA   
Sbjct: 1   MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 60

Query: 190 FNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGP 249
           FN+++ ++ +   K+    G+++I++ +      K+++ L+  GR ++ G  G  +IN  
Sbjct: 61  FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP- 119

Query: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309
                + K  S+I   L S   +  Q    A    +   +       L PV+   YP+ +
Sbjct: 120 --RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKPVIGSQYPLEK 170

Query: 310 IQEAHK-YMEANKNIGKIVLEL 330
           + EAH+  +  +   GK++L L
Sbjct: 171 VAEAHENIIHGSGATGKMILLL 192


>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
           sapiens]
          Length = 396

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 69/218 (31%), Positives = 101/218 (46%), Gaps = 36/218 (16%)

Query: 29  EVLLKVAASALNRADLMQRQGQYDPPPGASNI-------------------LGLEASGHV 69
           EV++KV A+++N  D+  R G      GA+ +                   LG + SG V
Sbjct: 73  EVIVKVHAASVNPIDVNMRSGY-----GATALNMKRDPLHVKIKGEEFPLTLGRDVSGVV 127

Query: 70  AELGPGCQGHWKIGDTAMALLPG---GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWL 126
            E G   + ++K GD   A +P    G  +++V V    +   P+ LT TQAA++P   L
Sbjct: 128 MECGLDVK-YFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVAL 186

Query: 127 TAFQLLHLVGNVQ----AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182
           TA+  ++ VG +      G  VLI     GVGT AIQ+ + A    +    SQ   ++  
Sbjct: 187 TAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMK-AWDAHVTAVCSQDASELVR 245

Query: 183 KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
           KLGA    +YK     E  LK  K    + ILD +GGS
Sbjct: 246 KLGADDVIDYKSGSVEE-QLKSLK--PFDFILDNVGGS 280


>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
           [Homo sapiens]
          Length = 373

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 64/234 (27%), Positives = 103/234 (44%), Gaps = 7/234 (2%)

Query: 29  EVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMA 88
           +V +K+ A+ +N +D+   QG Y   P    + G E    V  +G    G  K GD  + 
Sbjct: 72  DVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTG-LKPGDWVIP 130

Query: 89  LLPGGGQAQYVTV-PEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147
              G G  +   V  E  L+ +P  + L  AA +     TA+++L     +Q GD V+ +
Sbjct: 131 ANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQN 190

Query: 148 AGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKL-GAAAGFNYKKEDFSEATLK-- 203
           A  SGVG A IQ+    G   +     +  +Q ++++L    A     +E+     +K  
Sbjct: 191 ASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNF 250

Query: 204 FTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK 257
           F       L L+C+GG    + +  LA  G  V YG M    +   + S L+FK
Sbjct: 251 FKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASV-SLLIFK 303


>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160
           E LL   P+ + L+ A   +    LTA F LL + G V+ G+ V+++A    VG+   Q+
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161

Query: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
            ++ G   +   GS +K+   +KLG    FNYK  +  E TLK     G +   D +GG 
Sbjct: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221

Query: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250
           +    +  +   GR  + G +   +  GPL
Sbjct: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160
           E LL   P+ + L+ A   +    LTA F LL + G V+ G+ V+++A    VG+   Q+
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161

Query: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
            ++ G   +   GS +K+   +KLG    FNYK  +  E TLK     G +   D +GG 
Sbjct: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221

Query: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250
           +    +  +   GR  + G +   +  GPL
Sbjct: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160
           E LL   P+ + L+ A   +    LTA F LL + G V+ G+ V+++A    VG+   Q+
Sbjct: 103 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 161

Query: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
            ++ G   +   GS +K+   +KLG    FNYK  +  E TLK     G +   D +GG 
Sbjct: 162 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 221

Query: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPL 250
           +    +  +   GR  + G +   +  GPL
Sbjct: 222 FSNTVIGQMKKFGRIAICGAISTYNRTGPL 251


>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
          Length = 349

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 60/204 (29%), Positives = 96/204 (47%), Gaps = 17/204 (8%)

Query: 23  PSPGEGEVLLKVAASALNRAD---LMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGH 79
           P   +  V L+V A AL++ +   L + + + D  P     +G E +G V ++G      
Sbjct: 26  PVTEDNFVKLQVKACALSQINTKLLAEMKMKKDLFP-----VGREIAGIVLDVGSKVS-F 79

Query: 80  WKIGDTAMALLP----GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLV 135
           ++  D  + +LP      G  + V V E  L+  PE +T T+AA      + A+  LH +
Sbjct: 80  FQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYL 139

Query: 136 GNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEK----LGAAAGFN 191
            ++  G  VLI  G S  GT AIQL    GA  + TA S +  Q  E+    +      +
Sbjct: 140 SHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVS 199

Query: 192 YKKEDFSEATLKFTKGAGVNLILD 215
             K   +E+ L+ T G GV+++LD
Sbjct: 200 NGKVHVAESCLEETGGLGVDIVLD 223


>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
           [Homo sapiens]
          Length = 297

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 62/227 (27%), Positives = 98/227 (43%), Gaps = 7/227 (3%)

Query: 36  ASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQ 95
           A+ +N +D+   QG Y   P    + G E    V  +G    G  K GD  +    G G 
Sbjct: 3   AAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTG-LKPGDWVIPANAGLGT 61

Query: 96  AQYVTV-PEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154
            +   V  E  L+ +P  + L  AA +     TA+++L     +Q GD V+ +A  SGVG
Sbjct: 62  WRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVG 121

Query: 155 TAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKL-GAAAGFNYKKEDFSEATLK--FTKGAGV 210
            A IQ+    G   +     +  +Q ++++L    A     +E+     +K  F      
Sbjct: 122 QAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQP 181

Query: 211 NLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK 257
            L L+C+GG    + +  LA  G  V YG M    +   + S L+FK
Sbjct: 182 RLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASV-SLLIFK 227


>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
           sapiens]
          Length = 374

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 63/259 (24%), Positives = 99/259 (38%), Gaps = 63/259 (24%)

Query: 15  LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74
           L ++E+    P   EV +K+ A+A+   D     G  DP      ILG E +G V  +G 
Sbjct: 20  LSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGA-DPEGCFPVILGHEGAGIVESVGE 78

Query: 75  GCQGHWKIGDTAMAL-LPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQ--- 130
           G     K GDT + L +P  G+ ++   P+  L    + + +TQ   +     + F    
Sbjct: 79  GVT-KLKAGDTVIPLYIPQCGECKFCLNPKTNLC---QKIRVTQGKGLMPDGTSRFTCKG 134

Query: 131 --LLHLVGNVQAGDYVLIHA---------------------------------------- 148
             +LH +G     +Y ++                                          
Sbjct: 135 KTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSV 194

Query: 149 ----GLSGVGTAAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFNYKKEDFS----E 199
               GL GVG A I   ++AGA  ++     K K   A++ GA    N   +DFS    E
Sbjct: 195 CAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECIN--PQDFSKPIQE 252

Query: 200 ATLKFTKGAGVNLILDCIG 218
             ++ T G GV+   +CIG
Sbjct: 253 VLIEMTDG-GVDYSFECIG 270


>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
           sapiens]
          Length = 380

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 5/128 (3%)

Query: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155
           +QY  V +  L  I +   L +   +   + T +        V  G    +  GL GVG 
Sbjct: 153 SQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF-GLGGVGL 211

Query: 156 AAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYK--KEDFSEATLKFTKGAGVNL 212
           +A+   + AGA  ++    + +K   A+ LGA    N +   +   E  ++ TKG GV+ 
Sbjct: 212 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVDF 270

Query: 213 ILDCIGGS 220
            LDC GGS
Sbjct: 271 ALDCAGGS 278


>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
           sapiens]
          Length = 375

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206

Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211
           +AI   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 207 SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264

Query: 212 LILDCIG 218
              + IG
Sbjct: 265 FSFEVIG 271


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 61/267 (22%), Positives = 100/267 (37%), Gaps = 44/267 (16%)

Query: 11  GPENLYVKEVAKPSPGEGEVLLKVAASALNRADL----MQRQGQYDPPPGASNILGLEAS 66
           GP +L ++    P PG  EVLL++ +  +  +D+      R G +        +LG EAS
Sbjct: 16  GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVK--KPMVLGHEAS 73

Query: 67  GHVAELGPGCQGHWKIGDTAMALLPG-----------------------------GGQAQ 97
           G V ++G   + H K GD  +A+ PG                             G   +
Sbjct: 74  GTVEKVGSSVK-HLKPGD-RVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131

Query: 98  YVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157
           +          +P+ +T  + A I    +         G V  G  VL+  G   +G   
Sbjct: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLV-CGAGPIGMVT 188

Query: 158 IQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKF--TKGAGVNLIL 214
           + + +  GA   +VT  S  +L  A+++GA       KE   E   K     G    + +
Sbjct: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248

Query: 215 DCIGG-SYWEKNVNCLALDGRWVLYGL 240
           +C G  +  +  +      G  VL GL
Sbjct: 249 ECTGAEASIQAGIYATRSGGNLVLVGL 275


>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
           sapiens]
          Length = 375

 Score = 37.0 bits (84), Expect = 0.024
 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206

Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211
           +A+   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 207 SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264

Query: 212 LILDCIG 218
              + IG
Sbjct: 265 FSFEVIG 271


>gi|226246682 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score = 35.8 bits (81), Expect = 0.055
 Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 5/124 (4%)

Query: 120 AIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGV-GTAAIQLTRMAGAIPLV-TAGSQK 176
           AI    LT+   +   G++ AG +  ++ +G +G  G+ A Q+    G   +V   G+ +
Sbjct: 132 AIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHE 191

Query: 177 K-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235
           K + +  +LG  A  NYKK++ +E  L+ +  AGV++  D +GG+  +  ++ +  +   
Sbjct: 192 KCILLTSELGFDAAINYKKDNVAE-QLRESCPAGVDVYFDNVGGNISDTVISQMNENSHI 250

Query: 236 VLYG 239
           +L G
Sbjct: 251 ILCG 254


>gi|226246680 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score = 35.8 bits (81), Expect = 0.055
 Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 5/124 (4%)

Query: 120 AIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGV-GTAAIQLTRMAGAIPLV-TAGSQK 176
           AI    LT+   +   G++ AG +  ++ +G +G  G+ A Q+    G   +V   G+ +
Sbjct: 132 AIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHE 191

Query: 177 K-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235
           K + +  +LG  A  NYKK++ +E  L+ +  AGV++  D +GG+  +  ++ +  +   
Sbjct: 192 KCILLTSELGFDAAINYKKDNVAE-QLRESCPAGVDVYFDNVGGNISDTVISQMNENSHI 250

Query: 236 VLYG 239
           +L G
Sbjct: 251 ILCG 254


>gi|22748929 prostaglandin reductase 2 [Homo sapiens]
          Length = 351

 Score = 35.8 bits (81), Expect = 0.055
 Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 5/124 (4%)

Query: 120 AIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGV-GTAAIQLTRMAGAIPLV-TAGSQK 176
           AI    LT+   +   G++ AG +  ++ +G +G  G+ A Q+    G   +V   G+ +
Sbjct: 132 AIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHE 191

Query: 177 K-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235
           K + +  +LG  A  NYKK++ +E  L+ +  AGV++  D +GG+  +  ++ +  +   
Sbjct: 192 KCILLTSELGFDAAINYKKDNVAE-QLRESCPAGVDVYFDNVGGNISDTVISQMNENSHI 250

Query: 236 VLYG 239
           +L G
Sbjct: 251 ILCG 254


>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
           sapiens]
          Length = 375

 Score = 35.8 bits (81), Expect = 0.055
 Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 7/127 (5%)

Query: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF-GLGGVGL 206

Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211
           + +   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 207 SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264

Query: 212 LILDCIG 218
              + IG
Sbjct: 265 FSFEVIG 271


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 26/115 (22%), Positives = 42/115 (36%), Gaps = 8/115 (6%)

Query: 27  EGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTA 86
           E  +    AA+ ++ +     +    P  G + +    A       GPG +       T 
Sbjct: 456 EDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTE 515

Query: 87  MALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAG 141
             L+  GG+      P+G  +P+P           PE W+T  Q  H+    QAG
Sbjct: 516 EPLITAGGEESGSPPPDGPPLPLP--------TVAPERWITPAQREHVGMKGQAG 562


>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
          Length = 375

 Score = 33.1 bits (74), Expect = 0.35
 Identities = 61/261 (23%), Positives = 93/261 (35%), Gaps = 56/261 (21%)

Query: 8   KPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASG 67
           KPG P ++   EVA P   E  V +KV A+ L   + M+  G          ILG E +G
Sbjct: 17  KPGAPFSIEEVEVAPPKAKE--VRIKVVATGLCGTE-MKVLGSKHLDLLYPTILGHEGAG 73

Query: 68  HVAELGPGCQGHWKIGDTAMAL-LPGGGQA------------------------------ 96
            V  +G G     K GD  + L LP  G+                               
Sbjct: 74  IVESIGEGVSTV-KPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFT 132

Query: 97  ----------------QYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQA 140
                           +Y  + E  +  I     L +   I   + T F        V  
Sbjct: 133 CKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTP 192

Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYK--KEDF 197
           G    +  GL GVG + +   + AGA  ++    +++K + A++LGA    N +  K+  
Sbjct: 193 GSTCAVF-GLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPI 251

Query: 198 SEATLKFTKGAGVNLILDCIG 218
            E     T  AG++   + IG
Sbjct: 252 QEVLFDMT-DAGIDFCFEAIG 271


>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
          Length = 368

 Score = 33.1 bits (74), Expect = 0.35
 Identities = 61/261 (23%), Positives = 93/261 (35%), Gaps = 56/261 (21%)

Query: 8   KPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASG 67
           KPG P ++   EVA P   E  V +KV A+ L   + M+  G          ILG E +G
Sbjct: 17  KPGAPFSIEEVEVAPPKAKE--VRIKVVATGLCGTE-MKVLGSKHLDLLYPTILGHEGAG 73

Query: 68  HVAELGPGCQGHWKIGDTAMAL-LPGGGQA------------------------------ 96
            V  +G G     K GD  + L LP  G+                               
Sbjct: 74  IVESIGEGVSTV-KPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFT 132

Query: 97  ----------------QYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQA 140
                           +Y  + E  +  I     L +   I   + T F        V  
Sbjct: 133 CKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTP 192

Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYK--KEDF 197
           G    +  GL GVG + +   + AGA  ++    +++K + A++LGA    N +  K+  
Sbjct: 193 GSTCAVF-GLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPI 251

Query: 198 SEATLKFTKGAGVNLILDCIG 218
            E     T  AG++   + IG
Sbjct: 252 QEVLFDMT-DAGIDFCFEAIG 271


>gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]
          Length = 880

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 11/114 (9%)

Query: 2   LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61
           LA  + +PGGP +  ++E+A+ SP     LLKV   A   A     +    P PG+    
Sbjct: 640 LAGQWPEPGGPYDKAIQELAQGSPS----LLKVDLEAWKAAPTGSPKPAVTPGPGS---- 691

Query: 62  GLEASGHVAELGPGCQGHWKIGDTAMALLP--GGGQAQYVTVPEGLLMPIPEGL 113
            L+      + GP  +       T M  +P  GG      TV      P P  L
Sbjct: 692 -LKGKLGARQSGPRTKASLSAKGTHMRKVPPQGGQDCSASTVSASPEAPTPSPL 744


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,560,157
Number of Sequences: 37866
Number of extensions: 649337
Number of successful extensions: 1451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1401
Number of HSP's gapped (non-prelim): 52
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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