Guide to the Human Genome
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Search of human proteins with 115511032

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
         (359 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila...   723   0.0  
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]                     655   0.0  
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]                     655   0.0  
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]                     655   0.0  
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]                     655   0.0  
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]                     645   0.0  
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]              582   e-166
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]              575   e-164
gi|38201714 ELAV-like 1 [Homo sapiens]                                491   e-139
gi|4506447 RNA binding motif, single stranded interacting protei...   126   3e-29
gi|8400718 RNA binding motif, single stranded interacting protei...   126   3e-29
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s...   121   1e-27
gi|51317355 RNA binding motif, single stranded interacting prote...   117   2e-26
gi|51317351 RNA binding motif, single stranded interacting prote...   117   2e-26
gi|51317353 RNA binding motif, single stranded interacting prote...   116   3e-26
gi|4506449 RNA binding motif, single stranded interacting protei...   113   3e-25
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]     111   9e-25
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...   110   3e-24
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...   110   3e-24
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...   110   3e-24
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]             105   8e-23
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]     102   7e-22
gi|188219593 TIA1 protein isoform 1 [Homo sapiens]                    101   9e-22
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]            100   2e-21
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                     97   2e-20
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...    93   4e-19
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom...    92   7e-19
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo...    92   7e-19
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]      90   3e-18
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                89   8e-18

>gi|115511032 ELAV (embryonic lethal, abnormal vision,
           Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
          Length = 359

 Score =  723 bits (1866), Expect = 0.0
 Identities = 359/359 (100%), Positives = 359/359 (100%)

Query: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFG 60
           METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFG
Sbjct: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFG 60

Query: 61  SIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSA 120
           SIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSA
Sbjct: 61  SIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSA 120

Query: 121 SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180
           SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE
Sbjct: 121 SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180

Query: 181 EAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLD 240
           EAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLD
Sbjct: 181 EAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLD 240

Query: 241 NLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFG 300
           NLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFG
Sbjct: 241 NLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFG 300

Query: 301 AVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA 359
           AVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA
Sbjct: 301 AVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA 359


>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
          Length = 369

 Score =  655 bits (1689), Expect = 0.0
 Identities = 324/360 (90%), Positives = 344/360 (95%), Gaps = 2/360 (0%)

Query: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSG-NTEDSKTNLIVNYLPQNMTQEELKSLF 59
           ME Q+SNGPT +NT+NGP++ N NC SP+ +G  T+DSKTNLIVNYLPQNMTQEE +SLF
Sbjct: 11  MEPQVSNGPT-SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLF 69

Query: 60  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
           GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS
Sbjct: 70  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 129

Query: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
           ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEA
Sbjct: 130 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEA 189

Query: 180 EEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRL 239
           EEAIKGLNGQKP GATEPITVKFANNPSQK++QA+LSQLYQSPNRRYPGPL  QAQRFRL
Sbjct: 190 EEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRL 249

Query: 240 DNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPF 299
           DNLLNMAYGVKRFSP+TIDGMTSL G+NIPGH GTGWCIFVYNL+PD+DES+LWQ+FGPF
Sbjct: 250 DNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPF 309

Query: 300 GAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA 359
           GAV NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK HK+
Sbjct: 310 GAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS 369


>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
          Length = 366

 Score =  655 bits (1689), Expect = 0.0
 Identities = 324/360 (90%), Positives = 344/360 (95%), Gaps = 2/360 (0%)

Query: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSG-NTEDSKTNLIVNYLPQNMTQEELKSLF 59
           ME Q+SNGPT +NT+NGP++ N NC SP+ +G  T+DSKTNLIVNYLPQNMTQEE +SLF
Sbjct: 8   MEPQVSNGPT-SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLF 66

Query: 60  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
           GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS
Sbjct: 67  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 126

Query: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
           ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEA
Sbjct: 127 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEA 186

Query: 180 EEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRL 239
           EEAIKGLNGQKP GATEPITVKFANNPSQK++QA+LSQLYQSPNRRYPGPL  QAQRFRL
Sbjct: 187 EEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRL 246

Query: 240 DNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPF 299
           DNLLNMAYGVKRFSP+TIDGMTSL G+NIPGH GTGWCIFVYNL+PD+DES+LWQ+FGPF
Sbjct: 247 DNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPF 306

Query: 300 GAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA 359
           GAV NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK HK+
Sbjct: 307 GAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS 366


>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
          Length = 383

 Score =  655 bits (1689), Expect = 0.0
 Identities = 324/360 (90%), Positives = 344/360 (95%), Gaps = 2/360 (0%)

Query: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSG-NTEDSKTNLIVNYLPQNMTQEELKSLF 59
           ME Q+SNGPT +NT+NGP++ N NC SP+ +G  T+DSKTNLIVNYLPQNMTQEE +SLF
Sbjct: 25  MEPQVSNGPT-SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLF 83

Query: 60  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
           GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS
Sbjct: 84  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 143

Query: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
           ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEA
Sbjct: 144 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEA 203

Query: 180 EEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRL 239
           EEAIKGLNGQKP GATEPITVKFANNPSQK++QA+LSQLYQSPNRRYPGPL  QAQRFRL
Sbjct: 204 EEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRL 263

Query: 240 DNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPF 299
           DNLLNMAYGVKRFSP+TIDGMTSL G+NIPGH GTGWCIFVYNL+PD+DES+LWQ+FGPF
Sbjct: 264 DNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPF 323

Query: 300 GAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA 359
           GAV NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK HK+
Sbjct: 324 GAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS 383


>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
          Length = 366

 Score =  655 bits (1689), Expect = 0.0
 Identities = 324/360 (90%), Positives = 344/360 (95%), Gaps = 2/360 (0%)

Query: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSG-NTEDSKTNLIVNYLPQNMTQEELKSLF 59
           ME Q+SNGPT +NT+NGP++ N NC SP+ +G  T+DSKTNLIVNYLPQNMTQEE +SLF
Sbjct: 8   MEPQVSNGPT-SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLF 66

Query: 60  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
           GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS
Sbjct: 67  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 126

Query: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
           ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEA
Sbjct: 127 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEA 186

Query: 180 EEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRL 239
           EEAIKGLNGQKP GATEPITVKFANNPSQK++QA+LSQLYQSPNRRYPGPL  QAQRFRL
Sbjct: 187 EEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRL 246

Query: 240 DNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPF 299
           DNLLNMAYGVKRFSP+TIDGMTSL G+NIPGH GTGWCIFVYNL+PD+DES+LWQ+FGPF
Sbjct: 247 DNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPF 306

Query: 300 GAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA 359
           GAV NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK HK+
Sbjct: 307 GAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS 366


>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
          Length = 380

 Score =  645 bits (1664), Expect = 0.0
 Identities = 324/374 (86%), Positives = 344/374 (91%), Gaps = 16/374 (4%)

Query: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSG-NTEDSKTNLIVNYLPQNMTQEELKSLF 59
           ME Q+SNGPT +NT+NGP++ N NC SP+ +G  T+DSKTNLIVNYLPQNMTQEE +SLF
Sbjct: 8   MEPQVSNGPT-SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLF 66

Query: 60  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
           GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS
Sbjct: 67  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 126

Query: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
           ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEA
Sbjct: 127 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEA 186

Query: 180 EEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRL 239
           EEAIKGLNGQKP GATEPITVKFANNPSQK++QA+LSQLYQSPNRRYPGPL  QAQRFRL
Sbjct: 187 EEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRL 246

Query: 240 DNLLNMAYGVK--------------RFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAP 285
           DNLLNMAYGVK              RFSP+TIDGMTSL G+NIPGH GTGWCIFVYNL+P
Sbjct: 247 DNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSP 306

Query: 286 DADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDR 345
           D+DES+LWQ+FGPFGAV NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDR
Sbjct: 307 DSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDR 366

Query: 346 VLQVSFKTNKTHKA 359
           VLQVSFKTNK HK+
Sbjct: 367 VLQVSFKTNKAHKS 380


>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
          Length = 360

 Score =  582 bits (1500), Expect = e-166
 Identities = 294/360 (81%), Positives = 316/360 (87%), Gaps = 9/360 (2%)

Query: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFG 60
           ME+Q+  GP      NGP    N        G T+DSKTNLIVNYLPQNMTQ+E KSLFG
Sbjct: 9   MESQVGGGPAGPALPNGPLLGTN--------GATDDSKTNLIVNYLPQNMTQDEFKSLFG 60

Query: 61  SIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSA 120
           SIG+IESCKLVRDKITGQSLGYGFVNY DP DA+KAINTLNGL+LQTKTIKVSYARPSSA
Sbjct: 61  SIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSA 120

Query: 121 SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180
           SIRDANLYVSGLPKTM+QKE+EQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEAE
Sbjct: 121 SIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAE 180

Query: 181 EAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLD 240
           EAIKGLNGQKP GA EPITVKFANNPSQKT QA+L+ LYQS  RRY GPL  Q QRFRLD
Sbjct: 181 EAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLD 240

Query: 241 NLLNMAYGVKRFSPMTIDGMTSLAGINIP-GHPGTGWCIFVYNLAPDADESILWQMFGPF 299
           NLLNMAYGVKRFSP+ IDGM+ LAG+ +  G  G GWCIFVYNL+P+ADES+LWQ+FGPF
Sbjct: 241 NLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPF 300

Query: 300 GAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA 359
           GAVTNVKVIRDF TNKCKGFGFVTMTNYDEAAMAIASLNGYRLG+RVLQVSFKT+K HKA
Sbjct: 301 GAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA 360


>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
          Length = 367

 Score =  575 bits (1482), Expect = e-164
 Identities = 294/367 (80%), Positives = 316/367 (86%), Gaps = 16/367 (4%)

Query: 1   METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFG 60
           ME+Q+  GP      NGP    N        G T+DSKTNLIVNYLPQNMTQ+E KSLFG
Sbjct: 9   MESQVGGGPAGPALPNGPLLGTN--------GATDDSKTNLIVNYLPQNMTQDEFKSLFG 60

Query: 61  SIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSA 120
           SIG+IESCKLVRDKITGQSLGYGFVNY DP DA+KAINTLNGL+LQTKTIKVSYARPSSA
Sbjct: 61  SIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSA 120

Query: 121 SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180
           SIRDANLYVSGLPKTM+QKE+EQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEAE
Sbjct: 121 SIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAE 180

Query: 181 EAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLD 240
           EAIKGLNGQKP GA EPITVKFANNPSQKT QA+L+ LYQS  RRY GPL  Q QRFRLD
Sbjct: 181 EAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLD 240

Query: 241 NLLNMAYGVK-------RFSPMTIDGMTSLAGINIP-GHPGTGWCIFVYNLAPDADESIL 292
           NLLNMAYGVK       RFSP+ IDGM+ LAG+ +  G  G GWCIFVYNL+P+ADES+L
Sbjct: 241 NLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVL 300

Query: 293 WQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFK 352
           WQ+FGPFGAVTNVKVIRDF TNKCKGFGFVTMTNYDEAAMAIASLNGYRLG+RVLQVSFK
Sbjct: 301 WQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFK 360

Query: 353 TNKTHKA 359
           T+K HKA
Sbjct: 361 TSKQHKA 367


>gi|38201714 ELAV-like 1 [Homo sapiens]
          Length = 326

 Score =  491 bits (1264), Expect = e-139
 Identities = 237/321 (73%), Positives = 274/321 (85%), Gaps = 13/321 (4%)

Query: 38  KTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI 97
           +TNLIVNYLPQNMTQ+EL+SLF SIGE+ES KL+RDK+ G SLGYGFVNY+  KDAE+AI
Sbjct: 19  RTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAI 78

Query: 98  NTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           NTLNGLRLQ+KTIKVSYARPSS  I+DANLY+SGLP+TMTQK++E +FS++GRII SR+L
Sbjct: 79  NTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQ 217
           VDQ TG+SRGV FIRFDKR EAEEAI   NG KPPG++EPITVKFA NP+Q  N A+LSQ
Sbjct: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQ 198

Query: 218 LYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWC 277
           LY SP RR+ GP+  QAQRF             RFSPM +D M+ L+G+N+PG+  +GWC
Sbjct: 199 LYHSPARRFGGPVHHQAQRF-------------RFSPMGVDHMSGLSGVNVPGNASSGWC 245

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           IF+YNL  DADE ILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNY+EAAMAIASL
Sbjct: 246 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 305

Query: 338 NGYRLGDRVLQVSFKTNKTHK 358
           NGYRLGD++LQVSFKTNK+HK
Sbjct: 306 NGYRLGDKILQVSFKTNKSHK 326



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 2/101 (1%)

Query: 115 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFD 174
           A      I   NL V+ LP+ MTQ EL  LFS  G + +++++ D+V G S G GF+ + 
Sbjct: 10  AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69

Query: 175 KRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAIL 215
              +AE AI  LNG +    T  I V +A   S+    A L
Sbjct: 70  TAKDAERAINTLNGLRLQSKT--IKVSYARPSSEVIKDANL 108


>gi|4506447 RNA binding motif, single stranded interacting protein 1
           isoform c [Homo sapiens]
          Length = 403

 Score =  126 bits (316), Expect = 3e-29
 Identities = 80/215 (37%), Positives = 117/215 (54%), Gaps = 23/215 (10%)

Query: 19  TTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQ 78
           T+ NNN SS  +SG  + SKTNL +  LP + T ++L  L    G+I S K + DK T +
Sbjct: 42  TSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNK 101

Query: 79  SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQ 138
             GYGFV++  P  A+KA++ L    +Q +  K     P+       NLY+S LP +M +
Sbjct: 102 CKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDE 154

Query: 139 KELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG---QKPPGA- 194
           +ELE +   +G++I++RIL D  +G SRGVGF R +   + E  I   NG   + PPG  
Sbjct: 155 QELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVS 213

Query: 195 --TEPITVKFANNPSQKTNQAILSQLYQSPNRRYP 227
             TEP+  KFA+   +K          Q+PN+  P
Sbjct: 214 APTEPLLCKFADGGQKKR---------QNPNKYIP 239



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 261 TSLAGINIPGHPGTGWC------IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTN 314
           T+ +  N      +GW       +++  L P   +  L ++  P+G + + K I D  TN
Sbjct: 41  TTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTN 100

Query: 315 KCKGFGFVTMTNYDEAAMAIASL 337
           KCKG+GFV   +   A  A+++L
Sbjct: 101 KCKGYGFVDFDSPAAAQKAVSAL 123



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++ NL    DE  L  M  PFG V + +++RD ++   +G GF  M + ++    I   
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201

Query: 338 NG 339
           NG
Sbjct: 202 NG 203


>gi|8400718 RNA binding motif, single stranded interacting protein 1
           isoform a [Homo sapiens]
          Length = 406

 Score =  126 bits (316), Expect = 3e-29
 Identities = 80/215 (37%), Positives = 117/215 (54%), Gaps = 23/215 (10%)

Query: 19  TTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQ 78
           T+ NNN SS  +SG  + SKTNL +  LP + T ++L  L    G+I S K + DK T +
Sbjct: 42  TSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNK 101

Query: 79  SLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQ 138
             GYGFV++  P  A+KA++ L    +Q +  K     P+       NLY+S LP +M +
Sbjct: 102 CKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDE 154

Query: 139 KELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG---QKPPGA- 194
           +ELE +   +G++I++RIL D  +G SRGVGF R +   + E  I   NG   + PPG  
Sbjct: 155 QELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVS 213

Query: 195 --TEPITVKFANNPSQKTNQAILSQLYQSPNRRYP 227
             TEP+  KFA+   +K          Q+PN+  P
Sbjct: 214 APTEPLLCKFADGGQKKR---------QNPNKYIP 239



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 6/83 (7%)

Query: 261 TSLAGINIPGHPGTGWC------IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTN 314
           T+ +  N      +GW       +++  L P   +  L ++  P+G + + K I D  TN
Sbjct: 41  TTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTN 100

Query: 315 KCKGFGFVTMTNYDEAAMAIASL 337
           KCKG+GFV   +   A  A+++L
Sbjct: 101 KCKGYGFVDFDSPAAAQKAVSAL 123



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++ NL    DE  L  M  PFG V + +++RD ++   +G GF  M + ++    I   
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201

Query: 338 NG 339
           NG
Sbjct: 202 NG 203


>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
           sapiens]
          Length = 614

 Score =  121 bits (303), Expect = 1e-27
 Identities = 89/337 (26%), Positives = 158/337 (46%), Gaps = 60/337 (17%)

Query: 30  DSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYID 89
           D G  +    N+ +  L  ++  + L   F + G I SCK+  D+    S G+GFV++  
Sbjct: 90  DPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFET 147

Query: 90  PKDAEKAINTLNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKEL 141
            + A++AINT+NG+ L  + + V +        A   + ++   N+YV  LP  + ++ L
Sbjct: 148 HEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGL 207

Query: 142 EQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVK 201
           + LFSQ+G++++ +++ D  +G SR  GF+ F+K  EA++A+  +NG++  G        
Sbjct: 208 QDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG-------- 258

Query: 202 FANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMT 261
                                   Y G   ++ +R    N L      +RF  M  D + 
Sbjct: 259 ---------------------RLLYAGRAQKRVER---QNELK-----RRFEQMKQDRLR 289

Query: 262 SLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGF 321
              G+N          ++V NL    D+  L + F P+G +T+ KV+ +      KGFGF
Sbjct: 290 RYQGVN----------LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGF 337

Query: 322 VTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
           V  ++ +EA  A+  +NG  +G + L V+    K  +
Sbjct: 338 VCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEER 374



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 4/151 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L  ++T+  L   F   G I S ++ RD  T +SLGY ++N+  P DAE+A++T
Sbjct: 12  SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71

Query: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           +N   L+ + I++ +++  P        N+++  L  ++  K L   FS +G I++ ++ 
Sbjct: 72  MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
            D+    SRG GF+ F+    A++AI  +NG
Sbjct: 132 CDEHG--SRGFGFVHFETHEAAQQAINTMNG 160



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 60/219 (27%), Positives = 106/219 (48%), Gaps = 28/219 (12%)

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           TN+ V  LP ++ ++ L+ LF   G++ S K++RD  +G S  +GFVN+   ++A+KA+ 
Sbjct: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249

Query: 99  TLNGLRLQTKTIKVSYARPSSASIRD------------------ANLYVSGLPKTMTQKE 140
            +NG  +  + +    A+       +                   NLYV  L  ++   +
Sbjct: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309

Query: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200
           L + FS YG I +++++ +   G S+G GF+ F    EA +A+  +NG+     T+P+ V
Sbjct: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGRIV--GTKPLYV 365

Query: 201 KFANNPSQKTNQAILSQLYQ---SPNRRYPGPLAQQAQR 236
             A    ++  +AIL+  Y    S  R    PL    Q+
Sbjct: 366 ALAQRKEER--KAILTNQYMQRLSTMRTLSNPLLGSFQQ 402



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           IF+ NL    D   L+  F  FG + + KV  D + ++  GFGFV    ++ A  AI ++
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158

Query: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
           NG  L DR + V  FK+ +  +A
Sbjct: 159 NGMLLNDRKVFVGHFKSRREREA 181



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 17/61 (27%), Positives = 36/61 (59%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           ++V +L PD  E++L++ F P G + +++V RD  T +  G+ ++      +A  A+ ++
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72

Query: 338 N 338
           N
Sbjct: 73  N 73


>gi|51317355 RNA binding motif, single stranded interacting protein
           3 isoform 1 [Homo sapiens]
          Length = 437

 Score =  117 bits (293), Expect = 2e-26
 Identities = 79/225 (35%), Positives = 123/225 (54%), Gaps = 16/225 (7%)

Query: 1   METQLSNGPTCNNTAN-GPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLF 59
           ++T+ S  P  +  A   P+T +++ +S  +S   + SKTNL +  LP   T ++L  L 
Sbjct: 22  LQTKQSYAPAPHPMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLC 81

Query: 60  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
              G+I S K + DK T Q  GYGFV++  P  A+KA+ +L    +Q +  K     P+ 
Sbjct: 82  QPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT- 140

Query: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
                 NLY+S LP +M ++ELE +   +G +I++RIL D   G+SRGVGF R +   + 
Sbjct: 141 ------NLYISNLPISMDEQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKC 193

Query: 180 EEAIKGLNG---QKPPG---ATEPITVKFANNPSQK-TNQAILSQ 217
           E  I+  NG   + PPG    +EP+  KFA+   +K  NQ+  +Q
Sbjct: 194 EVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQ 238



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 22/60 (36%), Positives = 35/60 (58%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++  L P   +  L ++  P+G + + K I D NTN+CKG+GFV   +   A  A+ASL
Sbjct: 63  LYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 122



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++ NL    DE  L  M  PFG V + +++RD N    +G GF  M + ++  + I   
Sbjct: 142 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 200

Query: 338 NG 339
           NG
Sbjct: 201 NG 202


>gi|51317351 RNA binding motif, single stranded interacting protein
           3 isoform 2 [Homo sapiens]
          Length = 420

 Score =  117 bits (293), Expect = 2e-26
 Identities = 79/225 (35%), Positives = 123/225 (54%), Gaps = 16/225 (7%)

Query: 1   METQLSNGPTCNNTAN-GPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLF 59
           ++T+ S  P  +  A   P+T +++ +S  +S   + SKTNL +  LP   T ++L  L 
Sbjct: 22  LQTKQSYAPAPHPMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLC 81

Query: 60  GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
              G+I S K + DK T Q  GYGFV++  P  A+KA+ +L    +Q +  K     P+ 
Sbjct: 82  QPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT- 140

Query: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
                 NLY+S LP +M ++ELE +   +G +I++RIL D   G+SRGVGF R +   + 
Sbjct: 141 ------NLYISNLPISMDEQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKC 193

Query: 180 EEAIKGLNG---QKPPG---ATEPITVKFANNPSQK-TNQAILSQ 217
           E  I+  NG   + PPG    +EP+  KFA+   +K  NQ+  +Q
Sbjct: 194 EVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQ 238



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 22/60 (36%), Positives = 35/60 (58%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++  L P   +  L ++  P+G + + K I D NTN+CKG+GFV   +   A  A+ASL
Sbjct: 63  LYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 122



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++ NL    DE  L  M  PFG V + +++RD N    +G GF  M + ++  + I   
Sbjct: 142 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 200

Query: 338 NG 339
           NG
Sbjct: 201 NG 202


>gi|51317353 RNA binding motif, single stranded interacting protein
           3 isoform 3 [Homo sapiens]
          Length = 419

 Score =  116 bits (291), Expect = 3e-26
 Identities = 75/207 (36%), Positives = 115/207 (55%), Gaps = 15/207 (7%)

Query: 18  PTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITG 77
           P+T +++ +S  +S   + SKTNL +  LP   T ++L  L    G+I S K + DK T 
Sbjct: 39  PSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTN 98

Query: 78  QSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMT 137
           Q  GYGFV++  P  A+KA+ +L    +Q +  K     P+       NLY+S LP +M 
Sbjct: 99  QCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT-------NLYISNLPISMD 151

Query: 138 QKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG---QKPPG- 193
           ++ELE +   +G +I++RIL D   G+SRGVGF R +   + E  I+  NG   + PPG 
Sbjct: 152 EQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGI 210

Query: 194 --ATEPITVKFANNPSQK-TNQAILSQ 217
              +EP+  KFA+   +K  NQ+  +Q
Sbjct: 211 PAPSEPLLCKFADGGQKKRQNQSKYTQ 237



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 22/60 (36%), Positives = 35/60 (58%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++  L P   +  L ++  P+G + + K I D NTN+CKG+GFV   +   A  A+ASL
Sbjct: 62  LYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 121



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++ NL    DE  L  M  PFG V + +++RD N    +G GF  M + ++  + I   
Sbjct: 141 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 199

Query: 338 NG 339
           NG
Sbjct: 200 NG 201


>gi|4506449 RNA binding motif, single stranded interacting protein 2
           [Homo sapiens]
          Length = 407

 Score =  113 bits (282), Expect = 3e-25
 Identities = 71/194 (36%), Positives = 106/194 (54%), Gaps = 15/194 (7%)

Query: 26  SSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFV 85
           SS   +GN + SKTNL +  L    T ++L  L    G+I S K + DK T +  GYGFV
Sbjct: 43  SSSGSNGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFV 102

Query: 86  NYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLF 145
           ++  P  A+KA+  L    +Q +  K     P+       NLY+S LP +M ++ELE + 
Sbjct: 103 DFDSPSAAQKAVTALKASGVQAQMAKQQEQDPT-------NLYISNLPLSMDEQELEGML 155

Query: 146 SQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG---QKPPGA---TEPIT 199
             +G++I++RIL D  +G SRGVGF R +   + E  I   NG   + PPG    ++P+ 
Sbjct: 156 KPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLL 214

Query: 200 VKFAN-NPSQKTNQ 212
            KFA+  P ++ NQ
Sbjct: 215 CKFADGGPKKRQNQ 228



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 20/60 (33%), Positives = 33/60 (55%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++  L P   +  L ++  P+G + + K I D  TNKCKG+GFV   +   A  A+ +L
Sbjct: 58  LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++ NL    DE  L  M  PFG V + +++RD  +   +G GF  M + ++    I   
Sbjct: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195

Query: 338 NG 339
           NG
Sbjct: 196 NG 197


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score =  111 bits (278), Expect = 9e-25
 Identities = 84/329 (25%), Positives = 152/329 (46%), Gaps = 64/329 (19%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L +++  + L   F + G I SCK+V D+    S GYGFV++   + AE+AI  
Sbjct: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157

Query: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149
           +NG+ L  +  KV   R  S   R+A          N+Y+    + M  + L+ LF ++G
Sbjct: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215

Query: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209
             ++ +++ D+ +G S+G GF+ F++  +A++A+  +NG++  G                
Sbjct: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG---------------- 258

Query: 210 TNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIP 269
                         + Y G   ++ +R             ++F  M  D +T   G+N  
Sbjct: 259 -------------KQIYVGRAQKKVER--------QTELKRKFEQMKQDRITRYQGVN-- 295

Query: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329
                   ++V NL    D+  L + F PFG +T+ KV+ +    + KGFGFV  ++ +E
Sbjct: 296 --------LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEE 345

Query: 330 AAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
           A  A+  +NG  +  + L V+    K  +
Sbjct: 346 ATKAVTEMNGRIVATKPLYVALAQRKEER 374



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 50/151 (33%), Positives = 89/151 (58%), Gaps = 4/151 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L  ++T+  L   F   G I S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 12  SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71

Query: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           +N   ++ K +++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 72  MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
            D+    S+G GF+ F+ +  AE AI+ +NG
Sbjct: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 28/218 (12%)

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           TN+ +    ++M  E LK LFG  G   S K++ D+ +G+S G+GFV++   +DA+KA++
Sbjct: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249

Query: 99  TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 140
            +NG  L  K I V  A+                        +  NLYV  L   +  + 
Sbjct: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309

Query: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+    AT+P+ V
Sbjct: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIV--ATKPLYV 365

Query: 201 KFANNPSQKTNQAILSQLY---QSPNRRYPGPLAQQAQ 235
             A    ++  QA L+  Y    +  R  P P+    Q
Sbjct: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPVINPYQ 401



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 31/83 (37%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           IF+ NL    D   L+  F  FG + + KV+ D   N  KG+GFV     + A  AI  +
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158

Query: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
           NG  L DR + V  FK+ K  +A
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 24/71 (33%), Positives = 39/71 (54%)

Query: 117 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKR 176
           PS+ S   A+LYV  L   +T+  L + FS  G I++ R+  D +T  S G  ++ F + 
Sbjct: 3   PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62

Query: 177 IEAEEAIKGLN 187
            +AE A+  +N
Sbjct: 63  ADAERALDTMN 73



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 18/61 (29%), Positives = 36/61 (59%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           ++V +L PD  E++L++ F P G + +++V RD  T +  G+ +V      +A  A+ ++
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 338 N 338
           N
Sbjct: 73  N 73


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score =  110 bits (274), Expect = 3e-24
 Identities = 83/329 (25%), Positives = 155/329 (47%), Gaps = 64/329 (19%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L +++  + L   F + G I SCK+V D+    S GY FV++   + A+KAI  
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157

Query: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149
           +NG+ L  +  KV   R  S   R+A          N+Y+    + +  + L++LFSQ+G
Sbjct: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215

Query: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209
           + ++ +++ D   G S+G GF+ ++K  +A +A++ +NG++  G      + F     +K
Sbjct: 216 KTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISG-----KIIFVGRAQKK 269

Query: 210 TNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIP 269
                               + +QA+  R            +F  +  + ++   G+N  
Sbjct: 270 --------------------VERQAELKR------------KFEQLKQERISRYQGVN-- 295

Query: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329
                   +++ NL    D+  L + F PFG++T+ KV+      + KGFGFV  ++ +E
Sbjct: 296 --------LYIKNLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEE 345

Query: 330 AAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
           A  A+  +NG  +G + L V+    K  +
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEER 374



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 48/151 (31%), Positives = 89/151 (58%), Gaps = 4/151 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L  ++T+  L   F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71

Query: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
            D+    S+G  F+ F+ +  A++AI+ +NG
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNG 160



 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 27/196 (13%)

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           TN+ +    + +  E LK LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249

Query: 99  TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 140
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309

Query: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365

Query: 201 KFANNPSQK----TNQ 212
             A    ++    TNQ
Sbjct: 366 ALAQRKEERKAHLTNQ 381



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158

Query: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
           NG  L DR + V  FK+ K  +A
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 18/61 (29%), Positives = 35/61 (57%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           ++V +L  D  E++L++ F P G V +++V RD  T +  G+ +V      +A  A+ ++
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 338 N 338
           N
Sbjct: 73  N 73


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score =  110 bits (274), Expect = 3e-24
 Identities = 83/329 (25%), Positives = 155/329 (47%), Gaps = 64/329 (19%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L +++  + L   F + G I SCK+V D+    S GY FV++   + A+KAI  
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157

Query: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149
           +NG+ L  +  KV   R  S   R+A          N+Y+    + +  + L++LFSQ+G
Sbjct: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215

Query: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209
           + ++ +++ D   G S+G GF+ ++K  +A +A++ +NG++  G      + F     +K
Sbjct: 216 KTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISG-----KIIFVGRAQKK 269

Query: 210 TNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIP 269
                               + +QA+  R            +F  +  + ++   G+N  
Sbjct: 270 --------------------VERQAELKR------------KFEQLKQERISRYQGVN-- 295

Query: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329
                   +++ NL    D+  L + F PFG++T+ KV+      + KGFGFV  ++ +E
Sbjct: 296 --------LYIKNLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEE 345

Query: 330 AAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
           A  A+  +NG  +G + L V+    K  +
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEER 374



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 48/151 (31%), Positives = 89/151 (58%), Gaps = 4/151 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L  ++T+  L   F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71

Query: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
            D+    S+G  F+ F+ +  A++AI+ +NG
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNG 160



 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 27/196 (13%)

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           TN+ +    + +  E LK LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249

Query: 99  TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 140
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309

Query: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365

Query: 201 KFANNPSQK----TNQ 212
             A    ++    TNQ
Sbjct: 366 ALAQRKEERKAHLTNQ 381



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158

Query: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
           NG  L DR + V  FK+ K  +A
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 18/61 (29%), Positives = 35/61 (57%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           ++V +L  D  E++L++ F P G V +++V RD  T +  G+ +V      +A  A+ ++
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 338 N 338
           N
Sbjct: 73  N 73


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score =  110 bits (274), Expect = 3e-24
 Identities = 83/329 (25%), Positives = 155/329 (47%), Gaps = 64/329 (19%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L +++  + L   F + G I SCK+V D+    S GY FV++   + A+KAI  
Sbjct: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157

Query: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149
           +NG+ L  +  KV   R  S   R+A          N+Y+    + +  + L++LFSQ+G
Sbjct: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215

Query: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209
           + ++ +++ D   G S+G GF+ ++K  +A +A++ +NG++  G      + F     +K
Sbjct: 216 KTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISG-----KIIFVGRAQKK 269

Query: 210 TNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIP 269
                               + +QA+  R            +F  +  + ++   G+N  
Sbjct: 270 --------------------VERQAELKR------------KFEQLKQERISRYQGVN-- 295

Query: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329
                   +++ NL    D+  L + F PFG++T+ KV+      + KGFGFV  ++ +E
Sbjct: 296 --------LYIKNLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEE 345

Query: 330 AAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
           A  A+  +NG  +G + L V+    K  +
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEER 374



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 48/151 (31%), Positives = 89/151 (58%), Gaps = 4/151 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L  ++T+  L   F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71

Query: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
            D+    S+G  F+ F+ +  A++AI+ +NG
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNG 160



 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 27/196 (13%)

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           TN+ +    + +  E LK LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249

Query: 99  TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 140
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309

Query: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365

Query: 201 KFANNPSQK----TNQ 212
             A    ++    TNQ
Sbjct: 366 ALAQRKEERKAHLTNQ 381



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158

Query: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
           NG  L DR + V  FK+ K  +A
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 18/61 (29%), Positives = 35/61 (57%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           ++V +L  D  E++L++ F P G V +++V RD  T +  G+ +V      +A  A+ ++
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 338 N 338
           N
Sbjct: 73  N 73


>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
          Length = 375

 Score =  105 bits (261), Expect = 8e-23
 Identities = 76/315 (24%), Positives = 147/315 (46%), Gaps = 61/315 (19%)

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
           L V  L +++T+  +  LF  IG  +SCK++ +  +     Y FV + + +DA  A+  +
Sbjct: 11  LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAM 68

Query: 101 NGLRLQTKTIKVSYARPSSASIRDAN----LYVSGLPKTMTQKELEQLFSQYGRIITSRI 156
           NG ++  K +KV++A   S+  +D +    ++V  L   +T ++++  F+ +G+I  +R+
Sbjct: 69  NGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARV 128

Query: 157 LVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILS 216
           + D  TG S+G GF+ F  +++AE AI  + GQ            +      +TN A   
Sbjct: 129 VKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQ------------WLGGRQIRTNWA--- 173

Query: 217 QLYQSPNRRYPGPLAQQ---AQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPG 273
                  R+ P P + Q    ++ R ++++N +      SP                   
Sbjct: 174 ------TRKPPAPKSTQENNTKQLRFEDVVNQS------SPKNC---------------- 205

Query: 274 TGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMA 333
               ++   +A    + ++ Q F PFG +  ++V  +      KG+ FV  + ++ AA A
Sbjct: 206 ---TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHA 256

Query: 334 IASLNGYRLGDRVLQ 348
           I S+NG  +   V++
Sbjct: 257 IVSVNGTTIEGHVVK 271



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 50/188 (26%), Positives = 89/188 (47%), Gaps = 28/188 (14%)

Query: 23  NNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGY 82
           N  ++P        +  ++ V  L   +T E++KS F   G+I   ++V+D  TG+S GY
Sbjct: 81  NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGY 140

Query: 83  GFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA--RP--------------------SSA 120
           GFV++ +  DAE AI  + G  L  + I+ ++A  +P                    + +
Sbjct: 141 GFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQS 200

Query: 121 SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180
           S ++  +Y  G+   +T + + Q FS +G+I+  R+  +      +G  F+RF     A 
Sbjct: 201 SPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAA 254

Query: 181 EAIKGLNG 188
            AI  +NG
Sbjct: 255 HAIVSVNG 262



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 27/78 (34%), Positives = 46/78 (58%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +FV +L+P+     +   F PFG +++ +V++D  T K KG+GFV+  N  +A  AI  +
Sbjct: 99  VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158

Query: 338 NGYRLGDRVLQVSFKTNK 355
            G  LG R ++ ++ T K
Sbjct: 159 GGQWLGGRQIRTNWATRK 176



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 24/84 (28%), Positives = 47/84 (55%), Gaps = 5/84 (5%)

Query: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329
           G P T   ++V NL+ D  E ++ Q+F   G   + K+I +  +N    + FV    + +
Sbjct: 6   GQPRT---LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRD 60

Query: 330 AAMAIASLNGYRLGDRVLQVSFKT 353
           AA A+A++NG ++  + ++V++ T
Sbjct: 61  AAAALAAMNGRKILGKEVKVNWAT 84



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 46  LPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 105
           +   +T + ++  F   G+I   ++  +K      GY FV +   + A  AI ++NG  +
Sbjct: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265

Query: 106 QTKTIKVSYARPS 118
           +   +K  + + S
Sbjct: 266 EGHVVKCYWGKES 278


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score =  102 bits (253), Expect = 7e-22
 Identities = 80/327 (24%), Positives = 147/327 (44%), Gaps = 60/327 (18%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ V  L +++  + L     + G I SC +V D+    S GYGFV++   + AE+AI  
Sbjct: 100 NIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERAIKK 157

Query: 100 LNGLRL--------QTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 151
           +NG+ L        Q K+ K   A   + +    N+Y+    + M  + L+ LF ++G  
Sbjct: 158 MNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPA 217

Query: 152 ITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTN 211
           ++ +++ D+ +G S+G GF+ F++  +A++A+  +NG++  G                  
Sbjct: 218 LSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG------------------ 258

Query: 212 QAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGH 271
                       + Y G   ++ +R             + F  M  D +T    +N    
Sbjct: 259 -----------KQIYVGRAQKKVER--------QTELKRTFEQMKQDRITRYQVVN---- 295

Query: 272 PGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAA 331
                 ++V NL    D+  L + F PFG +T+ KV+ +    + KGFGFV  ++ +EA 
Sbjct: 296 ------LYVKNLDDGIDDERLRKAFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEAT 347

Query: 332 MAIASLNGYRLGDRVLQVSFKTNKTHK 358
            A+  +NG  +  + L V+    K  +
Sbjct: 348 KAVTEMNGRIVATKPLYVALAQRKEER 374



 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 63/214 (29%), Positives = 105/214 (49%), Gaps = 33/214 (15%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +    ++M  E LK LFG  G   S K++ D+ +G+S G+GFV++   +DA+KA++ 
Sbjct: 192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDE 250

Query: 100 LNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKEL 141
           +NG  L  K I V  A+                        +  NLYV  L   +  + L
Sbjct: 251 MNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERL 310

Query: 142 EQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVK 201
            + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+    AT+P+ V 
Sbjct: 311 RKAFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIV--ATKPLYVA 366

Query: 202 FANNPSQKTNQAILSQLYQS--------PNRRYP 227
            A    ++  QA L+  Y          PN+R P
Sbjct: 367 LAQRKEER--QAYLTNEYMQRMASVRAVPNQRAP 398



 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 49/151 (32%), Positives = 82/151 (54%), Gaps = 4/151 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L  ++T+  L   F   G I S ++ RD IT  S  Y +VN+   KDAE A++T
Sbjct: 12  SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71

Query: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           +N   ++ K +++ +++  PS       N++V  L K++  K L    S +G I++  ++
Sbjct: 72  MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVV 131

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
            D+    S+G GF+ F+    AE AIK +NG
Sbjct: 132 CDE--NGSKGYGFVHFETHEAAERAIKKMNG 160



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 64/273 (23%), Positives = 113/273 (41%), Gaps = 34/273 (12%)

Query: 117 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKR 176
           PS+ S   A+LYV  L   +T+  L + FS  G I++ RI  D +T  S    ++ F   
Sbjct: 3   PSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHT 62

Query: 177 IEAEEAIKGLNGQKPPGATEPITVKFA-NNPSQK---TNQAILSQLYQSPNRRYPGPLAQ 232
            +AE A+  +N     G  +P+ + ++  +PS +        +  L +S N +       
Sbjct: 63  KDAEHALDTMNFDVIKG--KPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS 120

Query: 233 QAQRFRLDNLL-----NMAYG-------------VKRFSPMTIDGMTSLAG--------- 265
                   N++     +  YG             +K+ + M ++G     G         
Sbjct: 121 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE 180

Query: 266 INIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMT 325
             +         +++ N   D D+  L  +FG FG   +VKV+ D  + K KGFGFV+  
Sbjct: 181 AELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFVSFE 239

Query: 326 NYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
            +++A  A+  +NG  L  + + V     K  +
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER 272



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           IFV NL    +   L+     FG + +  V+ D N +K  G+GFV    ++ A  AI  +
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSK--GYGFVHFETHEAAERAIKKM 158

Query: 338 NGYRL-GDRVLQVSFKTNKTHKA 359
           NG  L G +V    FK+ K  +A
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREA 181


>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
          Length = 375

 Score =  101 bits (252), Expect = 9e-22
 Identities = 77/321 (23%), Positives = 146/321 (45%), Gaps = 61/321 (19%)

Query: 35  EDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 94
           ++    L V  L +++T+  +  LF  IG  ++CK++ D  T  +  Y FV + + + A 
Sbjct: 3   DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60

Query: 95  KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 150
            A+  +NG ++  K +KV++A   S+  +D     +++V  L   +T ++++  F+ +GR
Sbjct: 61  AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120

Query: 151 IITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKT 210
           I  +R++ D  TG S+G GF+ F  + +AE AI+ + GQ            +      +T
Sbjct: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQ------------WLGGRQIRT 168

Query: 211 NQAILSQLYQSPNRRYPGPLA---QQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGIN 267
           N A          R+ P P +      ++   D ++N +      SP             
Sbjct: 169 NWA---------TRKPPAPKSTYESNTKQLSYDEVVNQS------SP------------- 200

Query: 268 IPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNY 327
                 +   ++   +     E ++ Q F PFG +  ++V  D      KG+ FV   ++
Sbjct: 201 ------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSH 248

Query: 328 DEAAMAIASLNGYRLGDRVLQ 348
           + AA AI S+NG  +   V++
Sbjct: 249 ESAAHAIVSVNGTTIEGHVVK 269



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 67/256 (26%), Positives = 113/256 (44%), Gaps = 40/256 (15%)

Query: 23  NNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGY 82
           N  ++P        +  ++ V  L   +T E++K+ F   G I   ++V+D  TG+S GY
Sbjct: 79  NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGY 138

Query: 83  GFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN------------- 126
           GFV++ +  DAE AI  + G  L  + I+ ++A    P+  S  ++N             
Sbjct: 139 GFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQS 198

Query: 127 ------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180
                 +Y  G+   +T++ + Q FS +G+I+  R+  D      +G  F+RF+    A 
Sbjct: 199 SPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAA 252

Query: 181 EAIKGLNGQKPPG-------ATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQ 233
            AI  +NG    G         E + +    NP Q+ NQ    Q Y    + Y    AQQ
Sbjct: 253 HAIVSVNGTTIEGHVVKCYWGKETLDM---INPVQQQNQIGYPQPYGQWGQWYGN--AQQ 307

Query: 234 AQRFRLDNLLNMAYGV 249
             ++  +     AYG+
Sbjct: 308 IGQYMPNGWQVPAYGM 323



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 27/78 (34%), Positives = 46/78 (58%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +FV +L+P+     +   F PFG +++ +V++D  T K KG+GFV+  N  +A  AI  +
Sbjct: 97  VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156

Query: 338 NGYRLGDRVLQVSFKTNK 355
            G  LG R ++ ++ T K
Sbjct: 157 GGQWLGGRQIRTNWATRK 174



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 2/76 (2%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           ++V NL+ D  E+++ Q+F   G   N K+I D   N    + FV    +  AA A+A++
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66

Query: 338 NGYRLGDRVLQVSFKT 353
           NG ++  + ++V++ T
Sbjct: 67  NGRKIMGKEVKVNWAT 82


>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
          Length = 392

 Score =  100 bits (249), Expect = 2e-21
 Identities = 78/330 (23%), Positives = 150/330 (45%), Gaps = 74/330 (22%)

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRD----KITGQSLG-----------YGFV 85
           L V  L +++T+  +  LF  IG  +SCK++ +    +    S+G           Y FV
Sbjct: 11  LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70

Query: 86  NYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDAN----LYVSGLPKTMTQKEL 141
            + + +DA  A+  +NG ++  K +KV++A   S+  +D +    ++V  L   +T +++
Sbjct: 71  EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 130

Query: 142 EQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVK 201
           +  F+ +G+I  +R++ D  TG S+G GF+ F  +++AE AI  + GQ            
Sbjct: 131 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQ------------ 178

Query: 202 FANNPSQKTNQAILSQLYQSPNRRYPGPLAQQ---AQRFRLDNLLNMAYGVKRFSPMTID 258
           +      +TN A          R+ P P + Q    ++ R ++++N +      SP    
Sbjct: 179 WLGGRQIRTNWA---------TRKPPAPKSTQENNTKQLRFEDVVNQS------SPKNC- 222

Query: 259 GMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKG 318
                              ++   +A    + ++ Q F PFG +  ++V  +      KG
Sbjct: 223 ------------------TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KG 258

Query: 319 FGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 348
           + FV  + ++ AA AI S+NG  +   V++
Sbjct: 259 YSFVRFSTHESAAHAIVSVNGTTIEGHVVK 288



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 50/188 (26%), Positives = 89/188 (47%), Gaps = 28/188 (14%)

Query: 23  NNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGY 82
           N  ++P        +  ++ V  L   +T E++KS F   G+I   ++V+D  TG+S GY
Sbjct: 98  NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGY 157

Query: 83  GFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA--RP--------------------SSA 120
           GFV++ +  DAE AI  + G  L  + I+ ++A  +P                    + +
Sbjct: 158 GFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQS 217

Query: 121 SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180
           S ++  +Y  G+   +T + + Q FS +G+I+  R+  +      +G  F+RF     A 
Sbjct: 218 SPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAA 271

Query: 181 EAIKGLNG 188
            AI  +NG
Sbjct: 272 HAIVSVNG 279



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 27/78 (34%), Positives = 46/78 (58%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +FV +L+P+     +   F PFG +++ +V++D  T K KG+GFV+  N  +A  AI  +
Sbjct: 116 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 175

Query: 338 NGYRLGDRVLQVSFKTNK 355
            G  LG R ++ ++ T K
Sbjct: 176 GGQWLGGRQIRTNWATRK 193



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 18/99 (18%)

Query: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRD----FNTNKCKGFG----- 320
           G P T   ++V NL+ D  E ++ Q+F   G   + K+I +       N   GF      
Sbjct: 6   GQPRT---LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHT 62

Query: 321 ------FVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKT 353
                 FV    + +AA A+A++NG ++  + ++V++ T
Sbjct: 63  SNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWAT 101



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 6/73 (8%)

Query: 46  LPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 105
           +   +T + ++  F   G+I   ++  +K      GY FV +   + A  AI ++NG  +
Sbjct: 229 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 282

Query: 106 QTKTIKVSYARPS 118
           +   +K  + + S
Sbjct: 283 EGHVVKCYWGKES 295


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 77/332 (23%), Positives = 146/332 (43%), Gaps = 72/332 (21%)

Query: 35  EDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 94
           ++    L V  L +++T+  +  LF  IG  ++CK++ D  T  +  Y FV + + + A 
Sbjct: 3   DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60

Query: 95  KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 139
            A+  +NG ++  K +KV++A   S+  +D                +++V  L   +T +
Sbjct: 61  AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120

Query: 140 ELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPIT 199
           +++  F+ +GRI  +R++ D  TG S+G GF+ F  + +AE AI+ + GQ          
Sbjct: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQ---------- 170

Query: 200 VKFANNPSQKTNQAILSQLYQSPNRRYPGPLA---QQAQRFRLDNLLNMAYGVKRFSPMT 256
             +      +TN A          R+ P P +      ++   D ++N +      SP  
Sbjct: 171 --WLGGRQIRTNWA---------TRKPPAPKSTYESNTKQLSYDEVVNQS------SP-- 211

Query: 257 IDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKC 316
                            +   ++   +     E ++ Q F PFG +  ++V  D      
Sbjct: 212 -----------------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------ 248

Query: 317 KGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 348
           KG+ FV   +++ AA AI S+NG  +   V++
Sbjct: 249 KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280



 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 69/253 (27%), Positives = 112/253 (44%), Gaps = 40/253 (15%)

Query: 26  SSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFV 85
           SS V S        ++ V  L   +T E++K+ F   G I   ++V+D  TG+S GYGFV
Sbjct: 93  SSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFV 152

Query: 86  NYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN---------------- 126
           ++ +  DAE AI  + G  L  + I+ ++A    P+  S  ++N                
Sbjct: 153 SFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPS 212

Query: 127 ---LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAI 183
              +Y  G+   +T++ + Q FS +G+I+  R+  D      +G  F+RF+    A  AI
Sbjct: 213 NCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAI 266

Query: 184 KGLNGQKPPG-------ATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQR 236
             +NG    G         E + +    NP Q+ NQ    Q Y    + Y    AQQ  +
Sbjct: 267 VSVNGTTIEGHVVKCYWGKETLDM---INPVQQQNQIGYPQPYGQWGQWYGN--AQQIGQ 321

Query: 237 FRLDNLLNMAYGV 249
           +  +     AYG+
Sbjct: 322 YMPNGWQVPAYGM 334



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 52/229 (22%)

Query: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
           LYV  L + +T+  + QLFSQ G     ++++D  T  +    F+ F +   A  A+  +
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66

Query: 187 NGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMA 246
           NG+K  G  + + V +A  PS +      S +  +          Q++Q           
Sbjct: 67  NGRKIMG--KEVKVNWATTPSSQKKDTSSSTVVST----------QRSQDH--------- 105

Query: 247 YGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVK 306
                                        + +FV +L+P+     +   F PFG +++ +
Sbjct: 106 -----------------------------FHVFVGDLSPEITTEDIKAAFAPFGRISDAR 136

Query: 307 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 355
           V++D  T K KG+GFV+  N  +A  AI  + G  LG R ++ ++ T K
Sbjct: 137 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 80/322 (24%), Positives = 147/322 (45%), Gaps = 66/322 (20%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L +++  + L   F + G+I S K++ D     S GY FV++ +   A++AI  
Sbjct: 99  NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156

Query: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149
           +NG  L  K  KV   R  +   R+A          N+Y+      M  + L+ +FS+YG
Sbjct: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214

Query: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209
           + ++ +++ D  +G S+G GF+ FD    A++A++ +NG+   G      + F     +K
Sbjct: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDING-----QLIFVGRAQKK 268

Query: 210 T-NQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINI 268
              QA L Q++            +Q +R R+        GVK                  
Sbjct: 269 VERQAELKQMF------------EQLKRERIRG----CQGVK------------------ 294

Query: 269 PGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYD 328
                    +++ NL    D+  L   F  FG+++ VKV+++    + KGFG +  ++ +
Sbjct: 295 ---------LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPE 343

Query: 329 EAAMAIASLNGYRLGDRVLQVS 350
           +A  A+  +NG  LG + L ++
Sbjct: 344 DATKAMTEMNGRILGSKPLSIA 365



 Score = 89.0 bits (219), Expect = 6e-18
 Identities = 46/152 (30%), Positives = 95/152 (62%), Gaps = 4/152 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L  ++T++ L   F ++G + S ++ RD++T +SLGY +VN++   DA+KA++T
Sbjct: 11  SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70

Query: 100 LNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           +N   ++ K+I++ +++  +   R    N+++  L K++  K L + FS +G+I++S+++
Sbjct: 71  MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQ 189
            D     S+G  F+ F  +  A+ AI+ +NG+
Sbjct: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGK 160



 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 49/169 (28%), Positives = 80/169 (47%), Gaps = 21/169 (12%)

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           TN+ +     +M  E LK +F   G+  S K++ D  +G+S G+GFV++   + A+KA+ 
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248

Query: 99  TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 140
            +NG  +  + I V  A                  R      +   LY+  L  T+  ++
Sbjct: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308

Query: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQ 189
           L   FS +G I  SR+ V Q  G S+G G I F    +A +A+  +NG+
Sbjct: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 2/76 (2%)

Query: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
           L +  L   +  E+L++ F S G I   K+++++  GQS G+G + +  P+DA KA+  +
Sbjct: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352

Query: 101 NGLRLQTKTIKVSYAR 116
           NG  L +K + ++ A+
Sbjct: 353 NGRILGSKPLSIALAQ 368



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +++ N   D D+  L  +F  +G   +VKV+ D ++ K KGFGFV+  +++ A  A+  +
Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEM 250

Query: 338 NGYRLGDRVLQVSFKTNKTHK 358
           NG  +  +++ V     K  +
Sbjct: 251 NGRDINGQLIFVGRAQKKVER 271



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +F+ NL    D   L++ F  FG + + KV+ D      KG+ FV   N   A  AI  +
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157

Query: 338 NGYRL-GDRVLQVSFKTNKTHKA 359
           NG  L G +V    FK  K  +A
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREA 180



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/69 (34%), Positives = 40/69 (57%)

Query: 119 SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIE 178
           +A  R A+LYV  L   +T+  L + FS  G +++ RI  DQVT  S G  ++ F +  +
Sbjct: 4   AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63

Query: 179 AEEAIKGLN 187
           A++A+  +N
Sbjct: 64  AQKALDTMN 72


>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
           sapiens]
          Length = 200

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 52/151 (34%), Positives = 86/151 (56%), Gaps = 4/151 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L   +T+  L   F   G I S ++ RDKIT +SLGY +VNY  P DA++A+ T
Sbjct: 3   SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62

Query: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           LN   ++ + +++ +++  PS       N+++  L KT+  K L  +FS +G I++ ++ 
Sbjct: 63  LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
            D+     +G GF+ F K+  AE AI  +NG
Sbjct: 123 CDEKG--PKGYGFVHFQKQESAERAIDVMNG 151



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 2/73 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L + +  + L ++F + G I SCK+  D+   +  GYGFV++   + AE+AI+ 
Sbjct: 91  NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPK--GYGFVHFQKQESAERAIDV 148

Query: 100 LNGLRLQTKTIKV 112
           +NG+ L  + I V
Sbjct: 149 MNGMFLNYRKIFV 161



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +F+ NL    D   L+ +F  FG + + KV  D      KG+GFV     + A  AI  +
Sbjct: 92  VFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGPKGYGFVHFQKQESAERAIDVM 149

Query: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
           NG  L  R + V  FK++K  +A
Sbjct: 150 NGMFLNYRKIFVGRFKSHKEREA 172


>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
           sapiens]
          Length = 200

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 52/151 (34%), Positives = 86/151 (56%), Gaps = 4/151 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           +L V  L   +T+  L   F   G I S ++ RDKIT +SLGY +VNY  P DA++A+ T
Sbjct: 3   SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62

Query: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
           LN   ++ + +++ +++  PS       N+++  L KT+  K L  +FS +G I++ ++ 
Sbjct: 63  LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122

Query: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
            D+     +G GF+ F K+  AE AI  +NG
Sbjct: 123 CDEKG--PKGYGFVHFQKQESAERAIDVMNG 151



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 2/73 (2%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L + +  + L ++F + G I SCK+  D+   +  GYGFV++   + AE+AI+ 
Sbjct: 91  NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPK--GYGFVHFQKQESAERAIDV 148

Query: 100 LNGLRLQTKTIKV 112
           +NG+ L  + I V
Sbjct: 149 MNGMFLNYRKIFV 161



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +F+ NL    D   L+ +F  FG + + KV  D      KG+GFV     + A  AI  +
Sbjct: 92  VFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGPKGYGFVHFQKQESAERAIDVM 149

Query: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
           NG  L  R + V  FK++K  +A
Sbjct: 150 NGMFLNYRKIFVGRFKSHKEREA 172


>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
          Length = 382

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 80/320 (25%), Positives = 150/320 (46%), Gaps = 61/320 (19%)

Query: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
           N+ +  L +++    L  LF + G I SCK+V D     S GY +V++     A +AI  
Sbjct: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164

Query: 100 LNGLRLQTKTIKVS---YARPSSASIRD------ANLYVSGLPKTMTQKELEQLFSQYGR 150
           +NG+RL  + + V    +    +A +R        N++V  +   +  ++L++LF +YG 
Sbjct: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224

Query: 151 IITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKT 210
             + +++ D  +G S+G GF+R++    A++A+  L+G+   G      V +     +K 
Sbjct: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDG-----KVLYVGRAQKKI 278

Query: 211 NQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPG 270
            +  L++L     RR+        +R RL          ++  P              PG
Sbjct: 279 ER--LAEL----RRRF--------ERLRLK---------EKSRP--------------PG 301

Query: 271 HPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEA 330
            P     I++ NL    ++  L + F  FG+++  KV+ +    + KGFG V  ++++EA
Sbjct: 302 VP-----IYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEA 354

Query: 331 AMAIASLNGYRLGDRVLQVS 350
             A+  +NG  +G + L V+
Sbjct: 355 TKAVDEMNGRIVGSKPLHVT 374



 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 46/153 (30%), Positives = 81/153 (52%), Gaps = 4/153 (2%)

Query: 38  KTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAI 97
           K  L V  L  ++T++ L   F   G +   ++ RD +T   LGYG+VN+  P DAE A+
Sbjct: 17  KAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWAL 76

Query: 98  NTLNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSR 155
           NT+N   +  K  ++ +++P     +    N+++  L K++  + L  LFS +G I++ +
Sbjct: 77  NTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCK 136

Query: 156 ILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
           ++ D     S+G  ++ FD    A  AI  +NG
Sbjct: 137 VVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 46/169 (27%), Positives = 86/169 (50%), Gaps = 21/169 (12%)

Query: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
           TN+ V  +  ++  E+LK LF   G  ES K++RD  +G+S G+GFV Y   + A+KA+ 
Sbjct: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257

Query: 99  TLNGLRLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMTQKE 140
            L+G  +  K + V  A+     + +                    +Y+  L +T+  ++
Sbjct: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317

Query: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQ 189
           L++ FS +G I  ++++++   G  +G G + F    EA +A+  +NG+
Sbjct: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 1/81 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           +FV N+  D D+  L ++F  +G   +VKVIRD  + K KGFGFV    ++ A  A+  L
Sbjct: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDL 259

Query: 338 NGYRLGDRVLQVSFKTNKTHK 358
           +G  +  +VL V     K  +
Sbjct: 260 HGKSIDGKVLYVGRAQKKIER 280



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 18/61 (29%), Positives = 33/61 (54%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           ++V +L PD  E +L++ F P G +   ++ RD  T    G+G+V      +A  A+ ++
Sbjct: 20  LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79

Query: 338 N 338
           N
Sbjct: 80  N 80


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 57/186 (30%), Positives = 98/186 (52%), Gaps = 7/186 (3%)

Query: 26  SSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFV 85
           + P+   N +     + V  L + +++  L  LF   G + +  + +D++TGQ  GYGFV
Sbjct: 3   AGPISERNQD---ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFV 59

Query: 86  NYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIR-DANLYVSGLPKTMTQKELEQL 144
            ++  +DA+ AI  +N ++L  K I+V+ A   + ++   AN+++  L   + +K L   
Sbjct: 60  EFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDT 119

Query: 145 FSQYGRII-TSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFA 203
           FS +G I+ T +I+ D  TG S+G  FI F     ++ AI+ +NGQ       PITV +A
Sbjct: 120 FSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYL--CNRPITVSYA 177

Query: 204 NNPSQK 209
                K
Sbjct: 178 FKKDSK 183



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 1/82 (1%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNV-KVIRDFNTNKCKGFGFVTMTNYDEAAMAIAS 336
           IF+ NL P+ DE +L+  F  FG +    K++RD +T   KG+ F+   ++D +  AI +
Sbjct: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161

Query: 337 LNGYRLGDRVLQVSFKTNKTHK 358
           +NG  L +R + VS+   K  K
Sbjct: 162 MNGQYLCNRPITVSYAFKKDSK 183



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 21/73 (28%), Positives = 40/73 (54%)

Query: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
           ++V  L     E +LW++F   G V N  + +D  T + +G+GFV   + ++A  AI  +
Sbjct: 15  VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74

Query: 338 NGYRLGDRVLQVS 350
           N  +L  + ++V+
Sbjct: 75  NMIKLYGKPIRVN 87


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,509,260
Number of Sequences: 37866
Number of extensions: 586005
Number of successful extensions: 3017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 1610
Number of HSP's gapped (non-prelim): 1026
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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