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Search of human proteins with 11545918
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
sapiens]
(467 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa... 1025 0.0
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 436 e-122
gi|22538437 cathepsin B preproprotein [Homo sapiens] 159 7e-39
gi|22538435 cathepsin B preproprotein [Homo sapiens] 159 7e-39
gi|22538433 cathepsin B preproprotein [Homo sapiens] 159 7e-39
gi|22538431 cathepsin B preproprotein [Homo sapiens] 159 7e-39
gi|4503139 cathepsin B preproprotein [Homo sapiens] 159 7e-39
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens] 125 6e-29
gi|23110957 cathepsin H isoform b precursor [Homo sapiens] 89 1e-17
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] 89 1e-17
gi|23110962 cathepsin S preproprotein [Homo sapiens] 88 1e-17
gi|23110960 cathepsin L2 preproprotein [Homo sapiens] 82 8e-16
gi|22202619 cathepsin L1 preproprotein [Homo sapiens] 81 2e-15
gi|4503155 cathepsin L1 preproprotein [Homo sapiens] 81 2e-15
gi|22538442 cathepsin Z preproprotein [Homo sapiens] 79 7e-15
gi|4503151 cathepsin K preproprotein [Homo sapiens] 70 5e-12
gi|23110964 cathepsin W preproprotein [Homo sapiens] 69 7e-12
gi|4557501 cathepsin O preproprotein [Homo sapiens] 64 4e-10
gi|6042196 cathepsin F [Homo sapiens] 59 9e-09
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 43 5e-04
gi|134031945 SCO-spondin [Homo sapiens] 40 0.003
gi|161019170 mucin 5AC [Homo sapiens] 38 0.022
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 38 0.022
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 37 0.029
gi|37693519 BMP-binding endothelial regulator precursor protein ... 36 0.065
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 36 0.085
gi|156071452 nardilysin isoform b [Homo sapiens] 35 0.11
gi|156071450 nardilysin isoform a [Homo sapiens] 35 0.11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 35 0.15
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 34 0.32
>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
sapiens]
Length = 467
Score = 1025 bits (2651), Expect = 0.0
Identities = 467/467 (100%), Positives = 467/467 (100%)
Query: 1 MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD 60
MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD
Sbjct: 1 MWRCPLGLLLLLPLAGHLALGAQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRAD 60
Query: 61 DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD 120
DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD
Sbjct: 61 DCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWD 120
Query: 121 NCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGT 180
NCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGT
Sbjct: 121 NCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGT 180
Query: 181 IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD 240
IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD
Sbjct: 181 IRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASD 240
Query: 241 RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER 300
RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER
Sbjct: 241 RVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRRRGVVSDHCYPFSGRER 300
Query: 301 DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN 360
DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN
Sbjct: 301 DEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN 360
Query: 361 GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKY 420
GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKY
Sbjct: 361 GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKY 420
Query: 421 WTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH 467
WTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH
Sbjct: 421 WTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHH 467
>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
Length = 476
Score = 436 bits (1122), Expect = e-122
Identities = 210/426 (49%), Positives = 274/426 (64%), Gaps = 12/426 (2%)
Query: 45 GRYCQEQDLCCRGRADDCALPYLGA--ICYCDLFCNRTVSDCCPDFWDFCLGV---PPPF 99
G+YC+ CC R D C + A +CYCD FC+R SDCCPD+ FC PP
Sbjct: 54 GQYCRNFG-CCEDRDDGCVTEFYAANALCYCDKFCDRENSDCCPDYKSFCREEKEWPPHT 112
Query: 100 PPI--QGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGW 157
P +GC G+ Y +NCN CTC +QW+C Q CLV ++I+ +N+G+YGW
Sbjct: 113 QPWYPEGCFKDGQHYEEGSVIKENCNSCTCS-GQQWKCSQHVCLVRSELIEQVNKGDYGW 171
Query: 158 QAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLI 217
A N+S FWGMTL++G ++RLGT+ PS +++M+E+ L LP F AS KWP
Sbjct: 172 TAQNYSQFWGMTLEDGFKFRLGTLPPSPMLLSMNEMTASLPATTDLPEFFVASYKWPGWT 231
Query: 218 HEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDG 277
H PLDQ NCA SWAFSTA+VA+DR++I S G T LSPQNL+SC + GC G +D
Sbjct: 232 HGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDR 291
Query: 278 AWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDI 337
AWW+LR+RG+VS CYP +D+ C M SR+ GRGKR AT CPN+ +N I
Sbjct: 292 AWWYLRKRGLVSHACYPLF---KDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRI 348
Query: 338 YQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRH 397
YQ +P YR+ SN+ EIMKE+M+NGPVQA+M+V EDFF YK GIY H + E+YR+
Sbjct: 349 YQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKL 408
Query: 398 GTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWG 457
TH+VK+TGWG G+ K+W AANSWG +WGE G+FRI+RGVNE DIE ++ WG
Sbjct: 409 QTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAWG 468
Query: 458 RVGMED 463
++ D
Sbjct: 469 QLTSSD 474
>gi|22538437 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 159 bits (401), Expect = 7e-39
Identities = 104/324 (32%), Positives = 155/324 (47%), Gaps = 41/324 (12%)
Query: 145 DMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYR---LGTIRPSSSVMNMHEIYTVLNPGE 201
+++ +N+ N WQAG++ F+ + + R LG +P VM ++
Sbjct: 29 ELVNYVNKRNTTWQAGHN--FYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK------- 79
Query: 202 VLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNL 259
LP +F+A E+WP I E DQG+C WAF SDR+ IH+ H++ +S ++L
Sbjct: 80 -LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 260 LSC-DTHQQQGCRGGRLDGAWWFLRRRGVVSDH-------CYPFS--GRERDEAGPAPPC 309
L+C + GC GG AW F R+G+VS C P+S E G PPC
Sbjct: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198
Query: 310 MMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEV 369
K + P + + Y Y + +++K+IM E+ +NGPV+ V
Sbjct: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNS---YSVSNSEKDIMAEIYKNGPVEGAFSV 255
Query: 370 HEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGP 429
+ DF LYK G+Y H + G H+++I GWG E YW ANSW
Sbjct: 256 YSDFLLYKSGVYQHVTGEM--------MGGHAIRILGWGVE-----NGTPYWLVANSWNT 302
Query: 430 AWGERGHFRIVRGVNECDIESFVL 453
WG+ G F+I+RG + C IES V+
Sbjct: 303 DWGDNGFFKILRGQDHCGIESEVV 326
>gi|22538435 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 159 bits (401), Expect = 7e-39
Identities = 104/324 (32%), Positives = 155/324 (47%), Gaps = 41/324 (12%)
Query: 145 DMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYR---LGTIRPSSSVMNMHEIYTVLNPGE 201
+++ +N+ N WQAG++ F+ + + R LG +P VM ++
Sbjct: 29 ELVNYVNKRNTTWQAGHN--FYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK------- 79
Query: 202 VLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNL 259
LP +F+A E+WP I E DQG+C WAF SDR+ IH+ H++ +S ++L
Sbjct: 80 -LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 260 LSC-DTHQQQGCRGGRLDGAWWFLRRRGVVSDH-------CYPFS--GRERDEAGPAPPC 309
L+C + GC GG AW F R+G+VS C P+S E G PPC
Sbjct: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198
Query: 310 MMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEV 369
K + P + + Y Y + +++K+IM E+ +NGPV+ V
Sbjct: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNS---YSVSNSEKDIMAEIYKNGPVEGAFSV 255
Query: 370 HEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGP 429
+ DF LYK G+Y H + G H+++I GWG E YW ANSW
Sbjct: 256 YSDFLLYKSGVYQHVTGEM--------MGGHAIRILGWGVE-----NGTPYWLVANSWNT 302
Query: 430 AWGERGHFRIVRGVNECDIESFVL 453
WG+ G F+I+RG + C IES V+
Sbjct: 303 DWGDNGFFKILRGQDHCGIESEVV 326
>gi|22538433 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 159 bits (401), Expect = 7e-39
Identities = 104/324 (32%), Positives = 155/324 (47%), Gaps = 41/324 (12%)
Query: 145 DMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYR---LGTIRPSSSVMNMHEIYTVLNPGE 201
+++ +N+ N WQAG++ F+ + + R LG +P VM ++
Sbjct: 29 ELVNYVNKRNTTWQAGHN--FYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK------- 79
Query: 202 VLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNL 259
LP +F+A E+WP I E DQG+C WAF SDR+ IH+ H++ +S ++L
Sbjct: 80 -LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 260 LSC-DTHQQQGCRGGRLDGAWWFLRRRGVVSDH-------CYPFS--GRERDEAGPAPPC 309
L+C + GC GG AW F R+G+VS C P+S E G PPC
Sbjct: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198
Query: 310 MMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEV 369
K + P + + Y Y + +++K+IM E+ +NGPV+ V
Sbjct: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNS---YSVSNSEKDIMAEIYKNGPVEGAFSV 255
Query: 370 HEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGP 429
+ DF LYK G+Y H + G H+++I GWG E YW ANSW
Sbjct: 256 YSDFLLYKSGVYQHVTGEM--------MGGHAIRILGWGVE-----NGTPYWLVANSWNT 302
Query: 430 AWGERGHFRIVRGVNECDIESFVL 453
WG+ G F+I+RG + C IES V+
Sbjct: 303 DWGDNGFFKILRGQDHCGIESEVV 326
>gi|22538431 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 159 bits (401), Expect = 7e-39
Identities = 104/324 (32%), Positives = 155/324 (47%), Gaps = 41/324 (12%)
Query: 145 DMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYR---LGTIRPSSSVMNMHEIYTVLNPGE 201
+++ +N+ N WQAG++ F+ + + R LG +P VM ++
Sbjct: 29 ELVNYVNKRNTTWQAGHN--FYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK------- 79
Query: 202 VLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNL 259
LP +F+A E+WP I E DQG+C WAF SDR+ IH+ H++ +S ++L
Sbjct: 80 -LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 260 LSC-DTHQQQGCRGGRLDGAWWFLRRRGVVSDH-------CYPFS--GRERDEAGPAPPC 309
L+C + GC GG AW F R+G+VS C P+S E G PPC
Sbjct: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198
Query: 310 MMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEV 369
K + P + + Y Y + +++K+IM E+ +NGPV+ V
Sbjct: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNS---YSVSNSEKDIMAEIYKNGPVEGAFSV 255
Query: 370 HEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGP 429
+ DF LYK G+Y H + G H+++I GWG E YW ANSW
Sbjct: 256 YSDFLLYKSGVYQHVTGEM--------MGGHAIRILGWGVE-----NGTPYWLVANSWNT 302
Query: 430 AWGERGHFRIVRGVNECDIESFVL 453
WG+ G F+I+RG + C IES V+
Sbjct: 303 DWGDNGFFKILRGQDHCGIESEVV 326
>gi|4503139 cathepsin B preproprotein [Homo sapiens]
Length = 339
Score = 159 bits (401), Expect = 7e-39
Identities = 104/324 (32%), Positives = 155/324 (47%), Gaps = 41/324 (12%)
Query: 145 DMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYR---LGTIRPSSSVMNMHEIYTVLNPGE 201
+++ +N+ N WQAG++ F+ + + R LG +P VM ++
Sbjct: 29 ELVNYVNKRNTTWQAGHN--FYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK------- 79
Query: 202 VLPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNL 259
LP +F+A E+WP I E DQG+C WAF SDR+ IH+ H++ +S ++L
Sbjct: 80 -LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 260 LSC-DTHQQQGCRGGRLDGAWWFLRRRGVVSDH-------CYPFS--GRERDEAGPAPPC 309
L+C + GC GG AW F R+G+VS C P+S E G PPC
Sbjct: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198
Query: 310 MMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEV 369
K + P + + Y Y + +++K+IM E+ +NGPV+ V
Sbjct: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNS---YSVSNSEKDIMAEIYKNGPVEGAFSV 255
Query: 370 HEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGP 429
+ DF LYK G+Y H + G H+++I GWG E YW ANSW
Sbjct: 256 YSDFLLYKSGVYQHVTGEM--------MGGHAIRILGWGVE-----NGTPYWLVANSWNT 302
Query: 430 AWGERGHFRIVRGVNECDIESFVL 453
WG+ G F+I+RG + C IES V+
Sbjct: 303 DWGDNGFFKILRGQDHCGIESEVV 326
>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
Length = 463
Score = 125 bits (315), Expect = 6e-29
Identities = 92/319 (28%), Positives = 147/319 (46%), Gaps = 42/319 (13%)
Query: 143 DPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIR----PSSSVMNMHEIYTVLN 198
D + +KAIN W A + + +TL + IR G R P + + +L+
Sbjct: 171 DHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILH 230
Query: 199 PGEVLPTAFE-ASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQ 257
LPT+++ + N + +Q +C ++F++ + R+ I + TP+LSPQ
Sbjct: 231 ----LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQ 286
Query: 258 NLLSCDTHQQQGCRGG---RLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSR 314
++SC + Q GC GG + G + + G+V + C+P++G + PC M
Sbjct: 287 EVVSCSQYAQ-GCEGGFPYLIAGK--YAQDFGLVEEACFPYTGTDS-------PCKMKE- 335
Query: 315 AMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFF 374
C Y + Y + G N+ + EL+ +GP+ EV++DF
Sbjct: 336 -----------DCFRYYSSE---YHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFL 381
Query: 375 LYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGER 434
YK GIY HT L P H+V + G+G ++ + YW NSWG WGE
Sbjct: 382 HYKKGIYHHT--GLRDPFNPFELTNHAVLLVGYGTDSASG---MDYWIVKNSWGTGWGEN 436
Query: 435 GHFRIVRGVNECDIESFVL 453
G+FRI RG +EC IES +
Sbjct: 437 GYFRIRRGTDECAIESIAV 455
>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
Length = 323
Score = 88.6 bits (218), Expect = 1e-17
Identities = 67/237 (28%), Positives = 100/237 (42%), Gaps = 42/237 (17%)
Query: 215 NLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSC-DTHQQQGCRGG 273
N + +QG C W FST ++I + G M L+ Q L+ C GC+GG
Sbjct: 115 NFVSPVKNQGACGSCWTFSTTGALESAIAI-ATGKMLS-LAEQQLVDCAQDFNNHGCQGG 172
Query: 274 RLDGAW-WFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYV 332
A+ + L +G++ + YP+ G++ +C +
Sbjct: 173 LPSQAFEYILYNKGIMGEDTYPYQGKD-------------------------GYC--KFQ 205
Query: 333 NNNDIYQVTPVYRLGSNDKEIMKELME-NGPVQALMEVHEDFFLYKGGIYSHTPVSLGRP 391
I V V + D+E M E + PV EV +DF +Y+ GIYS T P
Sbjct: 206 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK-TP 264
Query: 392 ERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDI 448
++ H+V G+GE+ + YW NSWGP WG G+F I RG N C +
Sbjct: 265 DKVN----HAVLAVGYGEKN-----GIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 312
>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
Length = 335
Score = 88.6 bits (218), Expect = 1e-17
Identities = 67/237 (28%), Positives = 100/237 (42%), Gaps = 42/237 (17%)
Query: 215 NLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSC-DTHQQQGCRGG 273
N + +QG C W FST ++I + G M L+ Q L+ C GC+GG
Sbjct: 127 NFVSPVKNQGACGSCWTFSTTGALESAIAI-ATGKMLS-LAEQQLVDCAQDFNNHGCQGG 184
Query: 274 RLDGAW-WFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYV 332
A+ + L +G++ + YP+ G++ +C +
Sbjct: 185 LPSQAFEYILYNKGIMGEDTYPYQGKD-------------------------GYC--KFQ 217
Query: 333 NNNDIYQVTPVYRLGSNDKEIMKELME-NGPVQALMEVHEDFFLYKGGIYSHTPVSLGRP 391
I V V + D+E M E + PV EV +DF +Y+ GIYS T P
Sbjct: 218 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK-TP 276
Query: 392 ERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDI 448
++ H+V G+GE+ + YW NSWGP WG G+F I RG N C +
Sbjct: 277 DKVN----HAVLAVGYGEKN-----GIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 324
>gi|23110962 cathepsin S preproprotein [Homo sapiens]
Length = 331
Score = 88.2 bits (217), Expect = 1e-17
Identities = 74/260 (28%), Positives = 115/260 (44%), Gaps = 50/260 (19%)
Query: 198 NPGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQ 257
NP +LP + + EK + E QG+C WAFS ++ + + G + LS Q
Sbjct: 110 NPNRILPDSVDWREK--GCVTEVKYQGSCGACWAFSAVGALEAQLKLKT-GKLVS-LSAQ 165
Query: 258 NLLSCDTHQ--QQGCRGGRLDGAW-WFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSR 314
NL+ C T + +GC GG + A+ + + +G+ SD YP+ ++ C S+
Sbjct: 166 NLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQK-------CQYDSK 218
Query: 315 AMGRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMEN-GPVQALMEV-HED 372
R AT Y P R ++++KE + N GPV ++ H
Sbjct: 219 Y-----RAATC----------SKYTELPYGR-----EDVLKEAVANKGPVSVGVDARHPS 258
Query: 373 FFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWG 432
FFLY+ G+Y + ++ H V + G+G D +YW NSWG +G
Sbjct: 259 FFLYRSGVYYEPSCT--------QNVNHGVLVVGYG-----DLNGKEYWLVKNSWGHNFG 305
Query: 433 ERGHFRIVRGV-NECDIESF 451
E G+ R+ R N C I SF
Sbjct: 306 EEGYIRMARNKGNHCGIASF 325
>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
Length = 334
Score = 82.4 bits (202), Expect = 8e-16
Identities = 64/226 (28%), Positives = 92/226 (40%), Gaps = 39/226 (17%)
Query: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQ-QQGCRGGRLDGAWW 280
+Q C WAFS ++ G + LS QNL+ C Q QGC GG + A+
Sbjct: 131 NQKQCGSCWAFSATGALEGQM-FRKTGKLVS-LSEQNLVDCSRPQGNQGCNGGFMARAFQ 188
Query: 281 FLRRRGVV-SDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQ 339
+++ G + S+ YP+ DE P NS N+
Sbjct: 189 YVKENGGLDSEESYPYVAV--DEICKYRP-------------------ENSVANDTGFTV 227
Query: 340 VTPVYRLGSNDKEIMKELMENGPVQALMEV-HEDFFLYKGGIYSHTPVSLGRPERYRRHG 398
V P +K +MK + GP+ M+ H F YK GIY P+ ++
Sbjct: 228 VAP-----GKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFE-------PDCSSKNL 275
Query: 399 THSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVN 444
H V + G+G E + KYW NSWGP WG G+ +I + N
Sbjct: 276 DHGVLVVGYGFEGANSNNS-KYWLVKNSWGPEWGSNGYVKIAKDKN 320
>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
Length = 333
Score = 81.3 bits (199), Expect = 2e-15
Identities = 63/233 (27%), Positives = 96/233 (41%), Gaps = 41/233 (17%)
Query: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQ-QQGCRGGRLDGAWW 280
+QG C WAFS ++ G + LS QNL+ C Q +GC GG +D A+
Sbjct: 131 NQGQCGSCWAFSATGALEGQM-FRKTGRLIS-LSEQNLVDCSGPQGNEGCNGGLMDYAFQ 188
Query: 281 FLRRRGVV-SDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQ 339
+++ G + S+ YP+ E ++ + P V N+ +
Sbjct: 189 YVQDNGGLDSEESYPYEATE----------------------ESCKYNPKYSVANDTGFV 226
Query: 340 VTPVYRLGSNDKEIMKELMENGPVQALMEV-HEDFFLYKGGIYSHTPVSLGRPERYRRHG 398
P +K +MK + GP+ ++ HE F YK GIY P+
Sbjct: 227 DIP-----KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFE-------PDCSSEDM 274
Query: 399 THSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRG-VNECDIES 450
H V + G+G E+ KYW NSWG WG G+ ++ + N C I S
Sbjct: 275 DHGVLVVGYGFESTESDNN-KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIAS 326
>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
Length = 333
Score = 81.3 bits (199), Expect = 2e-15
Identities = 63/233 (27%), Positives = 96/233 (41%), Gaps = 41/233 (17%)
Query: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQ-QQGCRGGRLDGAWW 280
+QG C WAFS ++ G + LS QNL+ C Q +GC GG +D A+
Sbjct: 131 NQGQCGSCWAFSATGALEGQM-FRKTGRLIS-LSEQNLVDCSGPQGNEGCNGGLMDYAFQ 188
Query: 281 FLRRRGVV-SDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQ 339
+++ G + S+ YP+ E ++ + P V N+ +
Sbjct: 189 YVQDNGGLDSEESYPYEATE----------------------ESCKYNPKYSVANDTGFV 226
Query: 340 VTPVYRLGSNDKEIMKELMENGPVQALMEV-HEDFFLYKGGIYSHTPVSLGRPERYRRHG 398
P +K +MK + GP+ ++ HE F YK GIY P+
Sbjct: 227 DIP-----KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFE-------PDCSSEDM 274
Query: 399 THSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRG-VNECDIES 450
H V + G+G E+ KYW NSWG WG G+ ++ + N C I S
Sbjct: 275 DHGVLVVGYGFESTESDNN-KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIAS 326
>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
Length = 303
Score = 79.3 bits (194), Expect = 7e-15
Identities = 57/216 (26%), Positives = 93/216 (43%), Gaps = 29/216 (13%)
Query: 226 CAGSWAFSTAAVASDRVSIHSLGHM-TPVLSPQNLLSCDTHQQQGCRGGRLDGAWWFLRR 284
C WA ++ + +DR++I G + +LS QN++ C C GG W + +
Sbjct: 89 CGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGN--AGSCEGGNDLSVWDYAHQ 146
Query: 285 RGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPVY 344
G+ + C + ++++ C ++ G H + N +++V
Sbjct: 147 HGIPDETCNNYQAKDQE-------CDKFNQC-GTCNEFKECHA----IRNYTLWRVGDYG 194
Query: 345 RLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKI 404
L +K +M E+ NGP+ + E Y GGIY+ + + H V +
Sbjct: 195 SLSGREK-MMAEIYANGPISCGIMATERLANYTGGIYAEYQDTT--------YINHVVSV 245
Query: 405 TGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIV 440
GWG + DG +YW NSWG WGERG RIV
Sbjct: 246 AGWG---ISDGT--EYWIVRNSWGEPWGERGWLRIV 276
>gi|4503151 cathepsin K preproprotein [Homo sapiens]
Length = 329
Score = 69.7 bits (169), Expect = 5e-12
Identities = 59/225 (26%), Positives = 94/225 (41%), Gaps = 43/225 (19%)
Query: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWWF 281
+QG C WAFS+ ++ G + LSPQNL+ C + GC GG + A+ +
Sbjct: 132 NQGQCGSCWAFSSVGALEGQLK-KKTGKLLN-LSPQNLVDC-VSENDGCGGGYMTNAFQY 188
Query: 282 LRR-RGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQV 340
+++ RG+ S+ YP+ G+E CM + GK A C Y+
Sbjct: 189 VQKNRGIDSEDAYPYVGQEES-------CMYNPT----GK---AAKCRG--------YRE 226
Query: 341 TPVYRLGSNDKEIMKELMENGPVQALMEVH-EDFFLYKGGIYSHTPVSLGRPERYRRHGT 399
P N+K + + + GPV ++ F Y G+Y +
Sbjct: 227 IPE----GNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLN------- 275
Query: 400 HSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVN 444
H+V G+G + + K+W NSWG WG +G+ + R N
Sbjct: 276 HAVLAVGYGIQ-----KGNKHWIIKNSWGENWGNKGYILMARNKN 315
>gi|23110964 cathepsin W preproprotein [Homo sapiens]
Length = 376
Score = 69.3 bits (168), Expect = 7e-12
Identities = 71/259 (27%), Positives = 97/259 (37%), Gaps = 52/259 (20%)
Query: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRL-DGAWW 280
DQ NC WA + A I + +S Q LL C GC GG + D
Sbjct: 146 DQKNCNCCWAMAAAGNIETLWRISFWDFVD--VSVQELLDCG-RCGDGCHGGFVWDAFIT 202
Query: 281 FLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQV 340
L G+ S+ YPF G+ R A C P Y + +
Sbjct: 203 VLNNSGLASEKDYPFQGKVR-----AHRCH-----------------PKKY---QKVAWI 237
Query: 341 TPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTH 400
L +N+ I + L GP+ + + + LY+ G+ TP + P+ H
Sbjct: 238 QDFIMLQNNEHRIAQYLATYGPITVTINM-KPLQLYRKGVIKATPTTCD-PQLV----DH 291
Query: 401 SVKITGWGEETLPDG---------------RTLKYWTAANSWGPAWGERGHFRIVRGVNE 445
SV + G+G +G YW NSWG WGE+G+FR+ RG N
Sbjct: 292 SVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNT 351
Query: 446 CDIESFVLGVWGRVGMEDM 464
C I F L RV DM
Sbjct: 352 CGITKFPL--TARVQKPDM 368
>gi|4557501 cathepsin O preproprotein [Homo sapiens]
Length = 321
Score = 63.5 bits (153), Expect = 4e-10
Identities = 66/260 (25%), Positives = 99/260 (38%), Gaps = 45/260 (17%)
Query: 199 PGEVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQN 258
P LP F+ +K ++ + +Q C G WAFS +I G LS Q
Sbjct: 104 PNVSLPLRFDWRDK--QVVTQVRNQQMCGGCWAFSVVGAVESAYAIK--GKPLEDLSVQQ 159
Query: 259 LLSCDTHQQQGCRGGRLDGAWWFLRRRGV--VSDHCYPFSGRERDEAGPAPPCMMHSRAM 316
++ C ++ GC GG A +L + V V D YPF +
Sbjct: 160 VIDC-SYNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQN----------------- 201
Query: 317 GRGKRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLY 376
G + +H S + Y + E+ K L+ GP+ +++ + Y
Sbjct: 202 GLCHYFSGSHSGFSIKGYS-------AYDFSDQEDEMAKALLTFGPLVVIVDA-VSWQDY 253
Query: 377 KGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGH 436
GGI H S H+V ITG+ + G T YW NSWG +WG G+
Sbjct: 254 LGGIIQHHCSS--------GEANHAVLITGFDKT----GST-PYWIVRNSWGSSWGVDGY 300
Query: 437 FRIVRGVNECDIESFVLGVW 456
+ G N C I V ++
Sbjct: 301 AHVKMGSNVCGIADSVSSIF 320
>gi|6042196 cathepsin F [Homo sapiens]
Length = 484
Score = 58.9 bits (141), Expect = 9e-09
Identities = 68/311 (21%), Positives = 126/311 (40%), Gaps = 50/311 (16%)
Query: 141 LVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPG 200
+V I+A+++G + + F +T +E L T+ M + +V G
Sbjct: 215 MVRAQKIQALDRGTAQYGV---TKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSV---G 268
Query: 201 EVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLL 260
++ P ++ K + + DQG C WAFS + ++ ++ LS Q LL
Sbjct: 269 DLAPPEWDWRSK--GAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLS--LSEQELL 324
Query: 261 SCDTHQQQGCRGGRLDGAWWFLRRRG-VVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRG 319
CD + C GG A+ ++ G + ++ Y + G H ++
Sbjct: 325 DCDK-MDKACMGGLPSNAYSAIKNLGGLETEDDYSYQG--------------HMQSCNFS 369
Query: 320 KRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGG 379
+A Y+N++ L N++++ L + GP+ + F Y+ G
Sbjct: 370 AEKAKV-----YINDS--------VELSQNEQKLAAWLAKRGPISVAINAFGMQF-YRHG 415
Query: 380 IYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRI 439
I P+ RP H+V + G+G + + +W NSWG WGE+G++ +
Sbjct: 416 I--SRPL---RPLCSPWLIDHAVLLVGYGNRS-----DVPFWAIKNSWGTDWGEKGYYYL 465
Query: 440 VRGVNECDIES 450
RG C + +
Sbjct: 466 HRGSGACGVNT 476
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 43.1 bits (100), Expect = 5e-04
Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 28/103 (27%)
Query: 48 CQEQDLCCR--GRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGC 105
C E + C C L YL + D C T + C PD + C
Sbjct: 2389 CDEYECACNCVNSTVSCPLGYLASTATND--CGCTTTTCLPD---------------KVC 2431
Query: 106 MHGGRIYPVLGTYW-DNCNRCTCQEN-------RQWQCDQEPC 140
+H IYPV G +W + C+ CTC + R QC Q+PC
Sbjct: 2432 VHRSTIYPV-GQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPC 2473
Score = 37.4 bits (85), Expect = 0.029
Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPC 140
C+H G+ YP + +CN C C+ N QW C E C
Sbjct: 350 CVHSGKRYPPGTSLSRDCNTCICR-NSQWICSNEEC 384
Score = 32.0 bits (71), Expect = 1.2
Identities = 13/36 (36%), Positives = 17/36 (47%), Gaps = 1/36 (2%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPC 140
C H G+ Y T CN C C++ R+W C C
Sbjct: 829 CFHQGKEYAPGETVKIGCNTCVCRD-RKWNCTDHVC 863
Score = 29.6 bits (65), Expect = 6.1
Identities = 24/88 (27%), Positives = 34/88 (38%), Gaps = 17/88 (19%)
Query: 54 CCRGRADDCALPYLGAICYCDLFCNRTVSD-CCPDFWDFCLGVPPPFPPIQGCMHGGRIY 112
C +A C L C++ R +D CCP++ C V PP+ C G +
Sbjct: 2296 CPTAKAPTCGL--------CEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERG--LQ 2345
Query: 113 PVLGTYWDNCNRCTCQENRQWQCDQEPC 140
P L N C+ N C +E C
Sbjct: 2346 PTL------TNPGECRPNFTCACRKEEC 2367
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 29/112 (25%)
Query: 34 GLHLRGIRDAGGRYCQEQDLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPD--FWD- 90
G R A G++C G+ +DC G + C CN CP WD
Sbjct: 830 GQEYRECAPACGQHC--------GKPEDC-----GELGSCVAGCN------CPLGLLWDP 870
Query: 91 --FCLGVPPPFPPIQGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPC 140
C VPP P C G R Y CNRC CQE W C C
Sbjct: 871 EGQC--VPPSLCP---CQLGARRYAPGSATMKECNRCICQERGLWNCTARHC 917
Score = 39.3 bits (90), Expect = 0.008
Identities = 42/157 (26%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 4 CPLGLL------LLLPLAGHLALGAQQGRGRRELAPG-----------LHLRGIRDAGGR 46
CPLGLL + P LGA R APG RG+ + R
Sbjct: 862 CPLGLLWDPEGQCVPPSLCPCQLGA------RRYAPGSATMKECNRCICQERGLWNCTAR 915
Query: 47 YCQEQDLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPF------- 99
+C Q C R L Y C C D C+ P
Sbjct: 916 HCPSQAFCPR------ELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCV 969
Query: 100 -PPIQGCMHGGRIYPVLGTYWDNCNRCTCQENRQWQC 135
P + C H G+ Y T ++CN C C+ RQW C
Sbjct: 970 PPDLCPCRHSGQWYLPNATIQEDCNVCVCR-GRQWHC 1005
Score = 30.4 bits (67), Expect = 3.6
Identities = 12/36 (33%), Positives = 14/36 (38%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPC 140
C H G +YP T C C+C C PC
Sbjct: 3144 CAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179
Score = 29.6 bits (65), Expect = 6.1
Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 6/69 (8%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQC--DQEPCLVDPDMIKAINQGNYGWQAGNH 162
C G +P +C CTCQE QW C D C +++ A +G Q H
Sbjct: 1333 CEWGRNSFPPGSVLQKDCGNCTCQEG-QWHCGGDGGHC---EELVPACAEGEALCQENGH 1388
Query: 163 SAFWGMTLD 171
G D
Sbjct: 1389 CVPHGWLCD 1397
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 37.7 bits (86), Expect = 0.022
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 17/92 (18%)
Query: 49 QEQDLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHG 108
Q LC D C P + C + + T S C P LG P C HG
Sbjct: 1006 QRAQLCEDHCVDGCFCPPGRS---CTVLDDITHSGCLP------LGQCP-------CTHG 1049
Query: 109 GRIYPVLGTYWDNCNRCTCQENRQWQCDQEPC 140
GR Y ++ C+ CTC WQC PC
Sbjct: 1050 GRTYSPGTSFNTTCSSCTC-SGGLWQCQDLPC 1080
Score = 37.0 bits (84), Expect = 0.038
Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPC 140
C++ G Y TY +C CTC R W C + PC
Sbjct: 396 CVYNGAAYAPGATYSTDCTNCTCSGGR-WSCQEVPC 430
Score = 35.8 bits (81), Expect = 0.085
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPCL 141
C+H Y T +CN CTC+ NR+W+C CL
Sbjct: 1516 CVHNEATYKPGETIRVDCNTCTCR-NRRWECSHRLCL 1551
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 37.7 bits (86), Expect = 0.022
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 17/92 (18%)
Query: 49 QEQDLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHG 108
Q LC D C P + C + + T S C P LG P C HG
Sbjct: 350 QRAQLCEDHCVDGCFCPPGRS---CTVLDDITHSGCLP------LGQCP-------CTHG 393
Query: 109 GRIYPVLGTYWDNCNRCTCQENRQWQCDQEPC 140
GR Y ++ C+ CTC WQC PC
Sbjct: 394 GRTYSPGTSFNTTCSSCTC-SGGLWQCQDLPC 424
Score = 35.8 bits (81), Expect = 0.085
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPCL 141
C+H Y T +CN CTC+ NR+W+C CL
Sbjct: 860 CVHNEATYKPGETIRVDCNTCTCR-NRRWECSHRLCL 895
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 37.4 bits (85), Expect = 0.029
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPCL 141
C+H Y T CN CTC ++R W+C +PCL
Sbjct: 865 CVHNEASYRAGQTIRVGCNTCTC-DSRMWRCTDDPCL 900
Score = 37.0 bits (84), Expect = 0.038
Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 105 CMHGGRIYPVLGTYWDNCNRCTCQENRQWQCDQEPC 140
C++ G Y TY +C CTC R W C + PC
Sbjct: 396 CVYNGAAYAPGATYSTDCTNCTCSGGR-WSCQEVPC 430
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 36.2 bits (82), Expect = 0.065
Identities = 39/152 (25%), Positives = 54/152 (35%), Gaps = 28/152 (18%)
Query: 33 PGLHLRGIR-DAGGRYCQEQDLC----CRGRADDCALPYLGAICYCDLFCNRTVSDCCPD 87
PG G++ G + E C C G C + + CCP
Sbjct: 164 PGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPK 223
Query: 88 FWDFCLGVPPPFP-PIQGCMHGGRIYPVLGTY-WDNCNRCTCQE---------NRQWQCD 136
CLG F P C+ +Y ++ +DNC CTC++ + CD
Sbjct: 224 ----CLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCD 279
Query: 137 Q------EPCL--VDPDMIKAINQGNYGWQAG 160
Q E CL V P+ IK GN +Q G
Sbjct: 280 QGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG 311
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 35.8 bits (81), Expect = 0.085
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 51 QDLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPP 101
Q+L C+GR + G C CD C + CCPD+ FC V P P
Sbjct: 25 QELSCKGRCFESF--ERGRECDCDAQCKK-YDKCCPDYESFCAEVHNPTSP 72
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 35.4 bits (80), Expect = 0.11
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 13/83 (15%)
Query: 270 CRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPN 329
C GR A W + RG D A P P M GR K ++T CP+
Sbjct: 18 CEAGRELAALWGIETRGRCEDSA---------AARPFPILAMP----GRNKAKSTCSCPD 64
Query: 330 SYVNNNDIYQVTPVYRLGSNDKE 352
N D+ + + V RLG+++ E
Sbjct: 65 LQPNGQDLGENSRVARLGADESE 87
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 35.4 bits (80), Expect = 0.11
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 13/83 (15%)
Query: 270 CRGGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPN 329
C GR A W + RG D A P P M GR K ++T CP+
Sbjct: 18 CEAGRELAALWGIETRGRCEDSA---------AARPFPILAMP----GRNKAKSTCSCPD 64
Query: 330 SYVNNNDIYQVTPVYRLGSNDKE 352
N D+ + + V RLG+++ E
Sbjct: 65 LQPNGQDLGENSRVARLGADESE 87
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 35.0 bits (79), Expect = 0.15
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 14/63 (22%)
Query: 51 QDLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGV-----------PPPF 99
Q+L C+GR + G C CD C + CCPD+ FC V P P
Sbjct: 25 QELSCKGRCFESF--ERGRECDCDAQCKK-YDKCCPDYESFCAEVKDNKKNRTKKKPTPK 81
Query: 100 PPI 102
PP+
Sbjct: 82 PPV 84
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 33.9 bits (76), Expect = 0.32
Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 3/50 (6%)
Query: 52 DLCCRGRADDCALPYLGAICYCDLFCNRTVSDCCPDFWDFCLGVPPPFPP 101
+L C+GR + G C CD C + CCPD+ FC V P P
Sbjct: 67 ELSCKGRCFESF--ERGRECDCDAQCKK-YDKCCPDYESFCAEVHNPTSP 113
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.486
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,544,723
Number of Sequences: 37866
Number of extensions: 1098513
Number of successful extensions: 2530
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 2391
Number of HSP's gapped (non-prelim): 116
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.