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Search of human proteins with 115430231
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115430231 REC8 homolog [Homo sapiens]
(547 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115430231 REC8 homolog [Homo sapiens] 1102 0.0
gi|115430229 REC8 homolog [Homo sapiens] 1102 0.0
gi|110349719 titin isoform N2-A [Homo sapiens] 74 3e-13
gi|5453994 RAD21 homolog [Homo sapiens] 72 2e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 60 4e-09
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 52 1e-06
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 49 9e-06
gi|116686120 periaxin isoform 2 [Homo sapiens] 49 9e-06
gi|222136644 RAD21-like 1 [Homo sapiens] 49 2e-05
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 45 1e-04
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 44 3e-04
gi|40353729 Ras and Rab interactor 3 [Homo sapiens] 43 6e-04
gi|61966919 hypothetical protein LOC442444 [Homo sapiens] 43 6e-04
gi|209529739 hypothetical protein LOC100132247 [Homo sapiens] 43 8e-04
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 43 8e-04
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 43 8e-04
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 42 0.001
gi|157074225 nuclear pore complex interacting protein-like 3 [Ho... 42 0.001
gi|17136078 VGF nerve growth factor inducible precursor [Homo sa... 42 0.001
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 42 0.001
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 42 0.001
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 42 0.001
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 42 0.001
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 42 0.001
gi|47132519 Ras association and pleckstrin homology domains 1 is... 42 0.001
gi|47078278 choline kinase alpha isoform b [Homo sapiens] 42 0.002
gi|47078276 choline kinase alpha isoform a [Homo sapiens] 42 0.002
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 41 0.002
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 41 0.002
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s... 41 0.002
>gi|115430231 REC8 homolog [Homo sapiens]
Length = 547
Score = 1102 bits (2850), Expect = 0.0
Identities = 547/547 (100%), Positives = 547/547 (100%)
Query: 1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL 60
MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL
Sbjct: 1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL 60
Query: 61 PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP 120
PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP
Sbjct: 61 PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP 120
Query: 121 NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPRE 180
NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPRE
Sbjct: 121 NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPRE 180
Query: 181 PERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLP 240
PERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLP
Sbjct: 181 PERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLP 240
Query: 241 PPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRR 300
PPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRR
Sbjct: 241 PPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRR 300
Query: 301 RRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPP 360
RRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPP
Sbjct: 301 RRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPP 360
Query: 361 ELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEIS 420
ELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEIS
Sbjct: 361 ELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEIS 420
Query: 421 LEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLE 480
LEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLE
Sbjct: 421 LEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLE 480
Query: 481 AVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLI 540
AVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLI
Sbjct: 481 AVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLI 540
Query: 541 QPGPRFH 547
QPGPRFH
Sbjct: 541 QPGPRFH 547
>gi|115430229 REC8 homolog [Homo sapiens]
Length = 547
Score = 1102 bits (2850), Expect = 0.0
Identities = 547/547 (100%), Positives = 547/547 (100%)
Query: 1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL 60
MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL
Sbjct: 1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL 60
Query: 61 PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP 120
PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP
Sbjct: 61 PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP 120
Query: 121 NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPRE 180
NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPRE
Sbjct: 121 NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPRE 180
Query: 181 PERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLP 240
PERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLP
Sbjct: 181 PERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLP 240
Query: 241 PPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRR 300
PPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRR
Sbjct: 241 PPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRR 300
Query: 301 RRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPP 360
RRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPP
Sbjct: 301 RRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPP 360
Query: 361 ELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEIS 420
ELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEIS
Sbjct: 361 ELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEIS 420
Query: 421 LEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLE 480
LEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLE
Sbjct: 421 LEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLE 480
Query: 481 AVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLI 540
AVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLI
Sbjct: 481 AVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLI 540
Query: 541 QPGPRFH 547
QPGPRFH
Sbjct: 541 QPGPRFH 547
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 73.9 bits (180), Expect = 3e-13
Identities = 104/399 (26%), Positives = 169/399 (42%), Gaps = 70/399 (17%)
Query: 143 DPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTE---PREPERIPVTVLPPEAITILEA 199
+PR+P P +P++ E +PE+ +PP E P+ PE P V+P + + +
Sbjct: 10487 EPRVP-PTKVPEVLPPKEV-VPEKKVPVPPAKKPEAPPPKVPEA-PKEVVPEKKVPV--- 10540
Query: 200 EPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEEL 259
P + E+ + +PEV + A E+ + IP P P EV + + PE+
Sbjct: 10541 PPPKKPEVPPTK-VPEVPKA------AVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEK- 10592
Query: 260 RLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKF 319
++ P EVTP + P PE++ PVPPP K+ ++ P K
Sbjct: 10593 KVPAAPPKK--PEVTPVKVPEAPKEVVPEKKVPVPPP-------------KKPEVPPTKV 10637
Query: 320 QEQLQTRAHCWECPMVQPPERTIRGPAELFRTPT-LSGWLPPELLGLWTHCAQPPPKAL- 377
E + + P PP+ P E+F P ++ PP + A PP +
Sbjct: 10638 PEVPKVAVPEKKVPEAIPPKPE-SPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVP 10696
Query: 378 -RRELPEEAAAEEERRKIEVP--SEIEVPREAL-EPSVPLMVSLEISLEAAEEEKSRISL 433
++ +PE+ A +K E+P EVP+E + E VPL+V + E +++
Sbjct: 10697 PKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVP-----KKPEAPPAKVPE 10751
Query: 434 IP----PEERWAWPE------VEAPEAPALPVVPELPEVPM------------EMPLVLP 471
+P PE++ A P+ + PE P PV+ E P VP+ E P +
Sbjct: 10752 VPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIA 10811
Query: 472 PELELLSLEAVHRAVALELQANREPDFSSLVSPLSPRRM 510
PE E+ E VA E EP+ P P+++
Sbjct: 10812 PEEEIAPEEEKPVPVAEE----EEPEVPPPAVPEEPKKI 10846
Score = 68.6 bits (166), Expect = 1e-11
Identities = 91/323 (28%), Positives = 133/323 (41%), Gaps = 39/323 (12%)
Query: 163 IPERVEEIPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELD 222
+P++VE PP+VP + REP +PV LP E + E E + E+ E E EV E +
Sbjct: 10077 VPKKVEAPPPKVPKK-REPVPVPVA-LPQEEEVLFEEEIVPEEEVLPEEE--EVLPEEEE 10132
Query: 223 LLIAEEEEAILLEIPRLPPP---APAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEEL 279
+L EEE +L E +PP P E E + PEE E +L EV P +
Sbjct: 10133 VL--PEEEEVLPEEEEIPPEEEEVPPEEEYV-----PEEEEFVPEEE--VLPEVKPKVPV 10183
Query: 280 RLPAP-------------PSPERRPP--VPPPPRRRRRRRLLFWDKETQISPEKFQEQLQ 324
P P P E PP VP P++ +R++ KE ++ P + E+ +
Sbjct: 10184 PAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIIL-PKEEEVLPVEVTEEPE 10242
Query: 325 TRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEE 384
E +PP R P + PE + PP + +++PEE
Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEE 10302
Query: 385 AAAEEERRKIEVPSEI-EVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWP 443
++K P+++ EVP++ E V L EA K R L
Sbjct: 10303 KVPVPVQKKEAPPAKVPEVPKKVPEKKV-----LVPKKEAVPPAKGRTVLEEKVSVAFRQ 10357
Query: 444 EVEAPEAPALPVV-PELPEVPME 465
EV E L VV E+ E+P E
Sbjct: 10358 EVVVKERLELEVVEAEVEEIPEE 10380
Score = 67.8 bits (164), Expect = 2e-11
Identities = 93/390 (23%), Positives = 157/390 (40%), Gaps = 66/390 (16%)
Query: 144 PRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPE-RIPVTVL-----PPEAITIL 197
PR P P + + +P++ E P +VP P++PE ++PV + PP + +
Sbjct: 9954 PRKPVPEEKKPV------PVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEV 10007
Query: 198 EAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIP--RLPPPAPAEVEG------ 249
+P+ E ++P ++++ A+ E +P ++P PAP +VE
Sbjct: 10008 PKKPVP------EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVP 10061
Query: 250 -IGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFW 308
+ + L PEE + T P+++ P P P++R PVP P + +LF
Sbjct: 10062 EVPKKLIPEEKKPT-----------PVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFE 10110
Query: 309 DK---ETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGL 365
++ E ++ PE+ + + E V P E I P E P ++P E +
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEI--PPEEEEVPPEEEYVPEEEEFV 10168
Query: 366 WTHCAQPPPKALRRELPEEAAAEEERRKIE-----VPSEIEVPREALEPSVPLMVSLEIS 420
P K ++P A E ++K+ +P + E P A P VP V +
Sbjct: 10169 PEEEVLPEVKP---KVPVPAPVPEIKKKVTEKKVVIPKKEEAP-PAKVPEVPKKVEEKRI 10224
Query: 421 LEAAEEEKSRISLIPPEERWAWPEVEAPEAP---------ALPVVPE-----LPEVPMEM 466
+ EEE + + E E E PE P A P VPE +PE P +
Sbjct: 10225 ILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPV 10284
Query: 467 PLVLPPELELLSLEAVHRAVALELQANREP 496
P + +S + V + +Q P
Sbjct: 10285 PKKVEAPPAKVSKKIPEEKVPVPVQKKEAP 10314
Score = 63.9 bits (154), Expect = 4e-10
Identities = 96/388 (24%), Positives = 147/388 (37%), Gaps = 64/388 (16%)
Query: 145 RLPSPFDIPQIRHLLEAAIPERVE--EIPPEVPTEPREPERIPVTVLPPEAITILEAEPI 202
R+ + ++ ++E E VE E P P P E+I PP + + P
Sbjct: 10408 RVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPA 10467
Query: 203 RMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLT 262
++ PEV ++ I EE+ + E PR+PP EV E + +++ +
Sbjct: 10468 KV---------PEVPKK-----IVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPV- 10512
Query: 263 GWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQ 322
P A E PP+ P PE++ PVPPP K+ ++ P K E
Sbjct: 10513 ---PPAKKPEAPPPKVPEAPKEVVPEKKVPVPPP-------------KKPEVPPTKVPEV 10556
Query: 323 LQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPP--------- 373
+ + P PP+ P P P E++ A PP
Sbjct: 10557 PKAAVPEKKVPEAIPPKPESPPP----EVPE----APKEVVPEKKVPAAPPKKPEVTPVK 10608
Query: 374 -PKALRRELPEEAAAEEERRKIEVP--SEIEVPREAL-EPSVPLMVSLEISLEAAE--EE 427
P+A + +PE+ +K EVP EVP+ A+ E VP + + E EE
Sbjct: 10609 VPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE 10668
Query: 428 KSRISL-IPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVHRAV 486
++L PP E PE AP +P +PE + PEL + + V + V
Sbjct: 10669 PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEV 10728
Query: 487 ALELQANREPDFSSLVSPLSPRRMAARV 514
E + LV P P A+V
Sbjct: 10729 VPEKKV-------PLVVPKKPEAPPAKV 10749
Score = 62.0 bits (149), Expect = 1e-09
Identities = 90/357 (25%), Positives = 144/357 (40%), Gaps = 59/357 (16%)
Query: 163 IPERVEEIPPEVPTEP--------------REPERI--PVTVLP--PEAITILEAEPIRM 204
IP++++ PP+VP EP RE E++ P +P P+ + E P+
Sbjct: 9828 IPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPR 9887
Query: 205 LEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGW 264
E+ +PEV + +A EEE + L VE E + EE +T
Sbjct: 9888 KEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYL-------VEEEEEYIHEEEEFITEE 9940
Query: 265 EPGALLMEVTPPEELRLPAPPSPERRPPVPPP-------------PRRRRRRRLLFWDKE 311
E ++ V P + +P P PE + PVP P P++ + + K+
Sbjct: 9941 E----VVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK 9996
Query: 312 TQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQ 371
+ P K E + + P V P++ PA++ P +P + + +
Sbjct: 9997 EKPPPAKVPEVPKKPVPEEKVP-VPVPKKVEAPPAKVPEVPKKP--VPEKKVPVPAPKKV 10053
Query: 372 PPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLM---VSLEISLEAAEEEK 428
P A E+P++ EE++ VP ++E P P VP V + ++L EE
Sbjct: 10054 EAPPAKVPEVPKK-LIPEEKKPTPVPKKVEAP----PPKVPKKREPVPVPVALPQEEEVL 10108
Query: 429 SRISLIP-----PEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLE 480
++P PEE PE E V+PE E+P E V PPE E + E
Sbjct: 10109 FEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEV-PPEEEYVPEE 10164
Score = 56.6 bits (135), Expect = 6e-08
Identities = 92/355 (25%), Positives = 139/355 (39%), Gaps = 56/355 (15%)
Query: 142 VDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTE-PREPERIPVTVLPPEAITILEAE 200
V P P +P+ A +PE +E+ PE P++PE P V +LE +
Sbjct: 10728 VVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEK 10787
Query: 201 PIRMLEIEGERELPEVSRRELDL-----LIAEEEEAILL---EIPRLPPPAPAEVEGIGE 252
P + E PEV ++ + EEE+ + + E P +PPPA E +
Sbjct: 10788 PAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEP---K 10844
Query: 253 ALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKET 312
+ PE+ +P A + PE++ + P R PP PP P + + +F K
Sbjct: 10845 KIIPEKKVPVIKKPEAPPPKEPEPEKV-IEKPKLKPRPPPPPPAPPKEDVKEKIFQLK-- 10901
Query: 313 QISPEKFQEQLQTRAHCWECPMVQP-PERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQ 371
I +K E+ Q P+ P E+ +R L PE +
Sbjct: 10902 AIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRK-------------LLPE--------RK 10940
Query: 372 PPP------KALRRELPEEAAAEEERRKIE------VPSEIEVPREALEPSVPLMVSLEI 419
P P K++ R+ PEE + E +K+E VP E P+ E VP + E
Sbjct: 10941 PEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVP-EPPPPKPVEEVEVPTVTKRER 10999
Query: 420 SL---EAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLP 471
+ E K I L PE + PE E PV PE P+ P+ +P
Sbjct: 11000 KIPEPTKVPEIKPAIPLPAPEPK-PKPEAEVKTIKPPPVEPE--PTPIAAPVTVP 11051
Score = 54.7 bits (130), Expect = 2e-07
Identities = 85/360 (23%), Positives = 146/360 (40%), Gaps = 66/360 (18%)
Query: 144 PRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREP---ERIPVTV-----LPPEAIT 195
P++P + P + IP++VE P+VP P++P E+ PV V P +
Sbjct: 9286 PKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVP 9345
Query: 196 ILEAEPIR----MLEIEGERELPEVSRRELDL-LIAEEEEAILLEIPRLPPPAPAEVEGI 250
+ +P+ + + ++E P E+ ++ EE+ I+ + PPPA E I
Sbjct: 9346 EVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPE---I 9402
Query: 251 GEALGPEELRLTGWEPGALLMEVTPPEEL-RLPAPPSPERRPPVP-------PPPRRRRR 302
+ PEE + + EV PP ++ LP P PE + VP PPPR
Sbjct: 9403 PKKKVPEERKPVPRKE----EEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVS 9458
Query: 303 RRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPEL 362
++ + +K ++ EK + R V+ + E
Sbjct: 9459 KKTVVEEKRF-VAEEKLSFAVPQR--------VEVTRHEVSAEEE--------------- 9494
Query: 363 LGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLE 422
W++ + ++ EE EEE ++ +E P E + ++S + E
Sbjct: 9495 ---WSYSEEEEGVSI-SVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAE 9550
Query: 423 AA---EEEKSRISLIP--PEERWAWPEVEAPEAPALPVVPELPEVPMEMP---LVLPPEL 474
A E ++ +I L P P + P + PEAP +VPE +VP +P V PP++
Sbjct: 9551 PAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPK-KIVPE-KKVPAPVPKKEKVPPPKV 9608
Score = 54.7 bits (130), Expect = 2e-07
Identities = 94/380 (24%), Positives = 142/380 (37%), Gaps = 87/380 (22%)
Query: 160 EAAIPERVEEIPPEVPTEPREPERIPVTVLPPEA---ITILEAEP------------IRM 204
E IP EE+PPE P E E +P + PE + + P I
Sbjct: 10144 EEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPK 10203
Query: 205 LEIEGERELPEVSRR--ELDLLIAEEEEAILLEIPRLP-------------PPAPAEVEG 249
E ++PEV ++ E +++ +EEE + +E+ P PP+ EVE
Sbjct: 10204 KEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEE 10263
Query: 250 IGEALGPEELRLTGWE---PGALLMEVTP-------PEELRLPAPPSPERRPP--VPPPP 297
+ PE ++ E P +E P PEE ++P P + PP VP P
Sbjct: 10264 VAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEE-KVPVPVQKKEAPPAKVPEVP 10322
Query: 298 RRRRRRRLLFWDKETQISPEKFQEQLQTRAHC-----------WECPMVQ------PPER 340
++ +++L KE + P K + L+ + E +V+ P E
Sbjct: 10323 KKVPEKKVLVPKKEA-VPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEE 10381
Query: 341 TIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEI 400
E F H + K + + EE E+ R IEV
Sbjct: 10382 EFHEVEEYFEEGEF-------------HEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAE 10428
Query: 401 EVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPV----- 455
EV E E EIS + +K ++P +E P + PE P V
Sbjct: 10429 EV--EVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKE----PPAKVPEVPKKIVVEEKV 10482
Query: 456 -VPELPEV-PMEMPLVLPPE 473
VPE P V P ++P VLPP+
Sbjct: 10483 RVPEEPRVPPTKVPEVLPPK 10502
Score = 50.8 bits (120), Expect = 3e-06
Identities = 95/426 (22%), Positives = 170/426 (39%), Gaps = 72/426 (16%)
Query: 72 QLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLPNHLAMMETLED 131
+ ++ V + +Y+VE+ HI+ + A+ + E +L P A +E
Sbjct: 9519 EAEVTEYEVMEEPEEYVVEEKLHIISKRVEAE-PAEVTERQEKKIVLKPKIPAKIEE--- 9574
Query: 132 APDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPP 191
P P + P P +P+ + + A +P++ + PP+VP EP++P +P +PP
Sbjct: 9575 -PPP-----AKVPEAPKKI-VPEKK--VPAPVPKKEKVPPPKVPEEPKKP--VPEKKVPP 9623
Query: 192 EAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIG 251
+ I + E P + V+ R + + +EE +L+ + + P A V
Sbjct: 9624 KVIKMEEPLPAK------------VTERHMQI---TQEEKVLVAVTKKEAPPKARVPEEP 9668
Query: 252 EALGPEELRL-----TGWEPGALLME----VTPPEELRLPAP---PSPERRPPVPPPPRR 299
+ PEE L EP A + E V E++ + AP P P + + R
Sbjct: 9669 KRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKER 9728
Query: 300 RRR--------RRLLFWDKETQISPEKFQEQLQTRAHCW-------ECPMVQPPERTIRG 344
+R +++ + ++F+E T + E + E I
Sbjct: 9729 AYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITE 9788
Query: 345 PAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPR 404
P + P +P E + T PP K L++ +PEE +K++ P P+
Sbjct: 9789 PEK----PIPVKPVPEEPVP--TKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPP----PK 9838
Query: 405 EALEPSVPLMVSLEISLEAAEEEK--SRISLIP--PEERWAWPEVEAPEAPALPVVPELP 460
EP + IS+ E+E+ + +P P+ A +V P P V +P
Sbjct: 9839 VPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPV-RVP 9897
Query: 461 EVPMEM 466
EVP E+
Sbjct: 9898 EVPKEL 9903
Score = 45.8 bits (107), Expect = 1e-04
Identities = 79/347 (22%), Positives = 134/347 (38%), Gaps = 76/347 (21%)
Query: 161 AAIPERVEEIPPEVPTEP-----------REPERIPVTVLPPEAITILEAEPIRMLEIEG 209
A +PE+ PP+V +P E E++ VT +P + I+ +P R E
Sbjct: 9167 AKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEE 9226
Query: 210 ERELPEVSRRELDLLIAEE--------EEAILLEIPRLPPPAPAEVEGIGEALGPEELRL 261
E+ + ++I+EE EE + + +P + E + E++ +
Sbjct: 9227 VIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQK----------EIVTEEKIHV 9276
Query: 262 TGWEPGALLMEVTPPEEL-RLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQ 320
A+ V PP ++ LP P+PE PVP P K+ + K
Sbjct: 9277 ------AISKRVEPPPKVPELPEKPAPEEVAPVPIP-------------KKVEPPAPKVP 9317
Query: 321 EQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRE 380
E + + E V P++ P ++ P +P E + P P A ++E
Sbjct: 9318 E-VPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKP--VPEEKI--------PVPVAKKKE 9366
Query: 381 LPEEAAAEEER-----RKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIP 435
P E ++ KI + ++ E E+ P+VP EI + EE+ +P
Sbjct: 9367 APPAKVPEVQKGVVTEEKITIVTQRE---ESPPPAVP-----EIPKKKVPEERKP---VP 9415
Query: 436 PEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAV 482
+E P + P P PV E VP+ + PP +S + V
Sbjct: 9416 RKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTV 9462
Score = 38.1 bits (87), Expect = 0.021
Identities = 71/362 (19%), Positives = 131/362 (36%), Gaps = 69/362 (19%)
Query: 138 GMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITIL 197
G+ SV RL + L ++E PP++P +P+ +PPE I +
Sbjct: 8901 GVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPV 8960
Query: 198 EAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILL----------EIPRLPPPAPAEV 247
A PI +L E + P R E+ +++ ++ EI + PPP +
Sbjct: 8961 VAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLI 9020
Query: 248 EGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLF 307
A PE + ++ +M +T +E++ E++ V
Sbjct: 9021 ----PAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAV-------------- 9062
Query: 308 WDKETQISPEKFQE-----QLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPEL 362
KE ++ E F+E +++ +E P + P+ + E+
Sbjct: 9063 -HKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYE---------EIKVEAKKEV 9112
Query: 363 LGLWTHCAQPPPKALRRELPEEAAAEE------ERRKIEVPSEI-----------EVPRE 405
W + + RE + EE ER I+V E+ +VP +
Sbjct: 9113 HEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEK 9172
Query: 406 ALEP-----SVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELP 460
P P++ +E + EEEK +++ +P + P+ + PV E+
Sbjct: 9173 KAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQ----KPSRTPVQEEVI 9228
Query: 461 EV 462
EV
Sbjct: 9229 EV 9230
Score = 36.2 bits (82), Expect = 0.079
Identities = 50/183 (27%), Positives = 76/183 (41%), Gaps = 34/183 (18%)
Query: 138 GMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITIL 197
G V LP P+ +L++ + +R EE P+V EP++ E++ +P
Sbjct: 10928 GEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKV--EPKKLEKVKKPAVP------- 10978
Query: 198 EAEPIRMLEIEGERELPEVSRRELDL----LIAEEEEAILLEIPRLPPPAPAEVEGIGEA 253
E P + +E E E+P V++RE + + E + AI L P P AEV+ I
Sbjct: 10979 EPPPPKPVE---EVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPP 11035
Query: 254 LGPEELRLTGWEPGALLMEVTPP---EELRLPAPPSPERRPPVP--------PPPRRRRR 302
P E EP + VT P ++ AP +P P P P R
Sbjct: 11036 --PVEP-----EPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAER 11088
Query: 303 RRL 305
R+L
Sbjct: 11089 RKL 11091
>gi|5453994 RAD21 homolog [Homo sapiens]
Length = 631
Score = 71.6 bits (174), Expect = 2e-12
Identities = 146/672 (21%), Positives = 237/672 (35%), Gaps = 168/672 (25%)
Query: 1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL 60
MFY VL + G A IWLAA +L K N+ + E I++
Sbjct: 1 MFYAHFVLSKR-GPLAKIWLAAHWDKKLTKAHVFECNLESSVESIIS------------- 46
Query: 61 PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP 120
P+ + +L S L +GV+R+Y ++ +YL+ D ++ A +D+ E
Sbjct: 47 PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAY- 105
Query: 121 NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEI---------- 170
N + + E D P + +D + F + Q R + E + E V I
Sbjct: 106 NAITLPEEFHDFDQPLPDLDDID--VAQQFSLNQSR-VEEITMREEVGNISILQENDFGD 162
Query: 171 ----PPEVPTEPREPERIPVTVLPPEAITILEA--------EPIRMLEIEGERELPEVSR 218
E+ E E + V + +LE+ E I LE E + +
Sbjct: 163 FGMDDREIMREGSAFEDDDMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGE 222
Query: 219 RE-----LDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEV 273
D LI+ + I + PPA +E + PE+ ++
Sbjct: 223 GNDGGILDDKLISNNDGGIFDD-----PPALSE----AGVMLPEQ---------PAHDDM 264
Query: 274 TPPEELRLPAPPSPERRPPVPPPP---------------------------RRRRRRRLL 306
+ + + P SP+ PV P P + +R+R L
Sbjct: 265 DEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKL 324
Query: 307 FWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIR------GPAELFRTPTLSGWLPP 360
D ++ + + QL + + PP + + G +LF P W
Sbjct: 325 IVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLW-NN 383
Query: 361 ELLGLWTHCAQP-PPKALRR--------------------ELPEEAAAEEERRK------ 393
LL L+T C P P+ LR+ E+P E ++ +++
Sbjct: 384 RLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEP 443
Query: 394 -IEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPA 452
IE PS ++ +E S + + + K + I PE +VE E P
Sbjct: 444 IIEEPSRLQ--ESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPP 501
Query: 453 LPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQANREPDFSS------------ 500
+ + PE P P L+ PELELL + + E E + +S
Sbjct: 502 VELPPEEP--PNICQLI--PELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWN 557
Query: 501 --------------------LVSPL-----SPRRMAARVFYLLLVLSAQQILHVKQEKPY 535
+S L + R+ AA FY LVL QQ + + QE+PY
Sbjct: 558 KRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPY 617
Query: 536 GRLLIQPGPRFH 547
++ PGPRFH
Sbjct: 618 SDIIATPGPRFH 629
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 60.5 bits (145), Expect = 4e-09
Identities = 85/290 (29%), Positives = 112/290 (38%), Gaps = 42/290 (14%)
Query: 198 EAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILL---EIPRLPPPAPAEVEGIGEAL 254
EA+P+ ++ E +L E+ LL EE + E P PPP + + E L
Sbjct: 415 EAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEEL 474
Query: 255 GPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQI 314
L P AL + P EE L PP P+ PPP L +E+ +
Sbjct: 475 PASPL------PEALHLS-RPLEESPLSPPPEES---PLSPPPESSPFSPL----EESPL 520
Query: 315 SPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPP 374
SP + + E P+ PPE + P F LS PPE L PPP
Sbjct: 521 SPPEESPP----SPALETPLSPPPEASPLSPP--FEESPLSP--PPEELP-----TSPPP 567
Query: 375 KALRRELPEEAAAEE---ERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRI 431
+A R P E + E + P E E S PL E S + E SR+
Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES-PLSPPPEESPLSPPPEASRL 626
Query: 432 SLIPPEERWAWPEVEAPEAPA--------LPVVPELPEVPMEMPLVLPPE 473
S P + + P E+P +P LPVV L P E PL PPE
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE 676
Score = 57.8 bits (138), Expect = 3e-08
Identities = 101/353 (28%), Positives = 126/353 (35%), Gaps = 51/353 (14%)
Query: 141 SVDPRLPSPFDIP---------QIRHLLEAAIPERVEEIPP--EVPTEPREPERIPVTVL 189
S+ P+ P P Q+ LEA + E + +PP E P P PE P T
Sbjct: 403 SMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSP-PPEESP-TSP 460
Query: 190 PPEAITILEAEPIRMLEIEGERELPEVSRR-ELDLLIAEEEEAILLEIPRLPPPAPAEVE 248
PPEA + + P L E +SR E L EE+ L P P +P E
Sbjct: 461 PPEASRL--SPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518
Query: 249 GIG--EALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLL 306
+ E P T P ++PP E P P PE P PPP R
Sbjct: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFE-ESPLSPPPEELPTSPPPEASR------ 571
Query: 307 FWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLW 366
+SP + + E PM PPE + P F LS PPE L
Sbjct: 572 -------LSPPPEESPMSPPPE--ESPMSPPPEASRLFPP--FEESPLSP--PPEESPL- 617
Query: 367 THCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEE 426
PPP+A R P E + + S + P E S PL V +S E
Sbjct: 618 ----SPPPEASRLSPPPEDSPMSPPPE---ESPMSPPPEVSRLS-PLPVVSRLSPPPEES 669
Query: 427 EKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSL 479
S PPEE P EA P P + P PPE L+SL
Sbjct: 670 PLSP----PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Score = 48.1 bits (113), Expect = 2e-05
Identities = 108/443 (24%), Positives = 150/443 (33%), Gaps = 99/443 (22%)
Query: 113 ELPSLLLPNHLAMMETLEDAP---DPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEE 169
ELP+ LP L + LE++P P +S P SPF LE + EE
Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE-SSPFSP------LEESPLSPPEE 525
Query: 170 IPP----EVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLI 225
PP E P P PE P++ PP + L P ELP E L
Sbjct: 526 SPPSPALETPLSP-PPEASPLS--PPFEESPLSPPP---------EELPTSPPPEASRLS 573
Query: 226 AEEEEAILL----EIPRLPPPAPAEV----EGIGEALGPEELRLTGWEPGALLMEVTPPE 277
EE+ + E P PPP + + E + PEE L+ P ++PP
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS---PPPEASRLSPPP 630
Query: 278 ELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQP 337
E P P PE P PPP + +++SP +L E P+ P
Sbjct: 631 E-DSPMSPPPEESPMSPPP-------------EVSRLSPLPVVSRLSPPPE--ESPLSPP 674
Query: 338 PERTIRGP----AELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELP----------- 382
PE + P + L P S PP A PPP+ LP
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPE----DSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 383 -----------------EEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAE 425
EE + + + E P + +P P + ++ +
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790
Query: 426 EEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVHRA 485
+ + PEE P+ E P +P P L P E L E LS
Sbjct: 791 QAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH 850
Query: 486 VALELQANREPDFSSLVSPLSPR 508
++ EL+ PLSPR
Sbjct: 851 LSPELEK----------PPLSPR 863
Score = 35.0 bits (79), Expect = 0.18
Identities = 104/393 (26%), Positives = 147/393 (37%), Gaps = 85/393 (21%)
Query: 54 QPPQPGL-PRPRFSLYLSAQLQIGVIRVYSQQ-CQYLVEDIQHILERLHRAQL-----QI 106
+P +P L PRP +LS Q + + ++ C V + H+ + L ++
Sbjct: 746 RPEEPHLSPRPE-EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL 804
Query: 107 RIDMETELPSLL-LPNHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHL---LEAA 162
+ +TE P L +P + +P P +S P P+ HL LE
Sbjct: 805 HLSPQTEEPHLSPVPEEPCL------SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP 858
Query: 163 IPERVEEIPPEVPTEPREPERIPVTVLPPE-AITILEAEPIRMLEIEGERELPEVSRREL 221
E PPE P + PE +P+ P E +++ L EP L GE P +S
Sbjct: 859 PLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP--ALSEPGE---PPLSPLPE 913
Query: 222 DLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRL 281
+L ++ E L P+L PP P + L P +T P AL +P EL
Sbjct: 914 ELPLSPSGEPSL--SPQLMPPDP-----LPPPLSP---IITAAAPPAL----SPLGELEY 959
Query: 282 PAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWE----CPMVQP 337
P + P P L ET ISP A+C + PM+ P
Sbjct: 960 PFGAKGDSDPESP----------LAAPILETPISP-------PPEANCTDPEPVPPMILP 1002
Query: 338 PE-RTIRGPAELFRTPTLSGWLPPELLGLWTHCAQP--------PPKALRRELPEEAA-- 386
P + GPA +P L LPP+ L H P P AL +P +
Sbjct: 1003 PSPGSPVGPA----SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPI 1058
Query: 387 ---------AEEERRKIEVPSEIEVPREALEPS 410
AE + E SE E P ALEPS
Sbjct: 1059 GKVVGVSDEAELHEMETEKVSEPECP--ALEPS 1089
Score = 31.2 bits (69), Expect = 2.6
Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 23/146 (15%)
Query: 160 EAAIPERVEEIPPEVPTEPR--EPERIPVTVLPPE-AITILEAEPIRMLEIEGERELPEV 216
E+ + + E P P E +PE +P +LPP + A PI M E P+
Sbjct: 970 ESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM-----EPLPPQC 1024
Query: 217 SRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALG--------------PEELRLT 262
S L+ + P LP P+ + IG+ +G E
Sbjct: 1025 SPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECP 1084
Query: 263 GWEPGALLMEVTPPEELRLPAP-PSP 287
EP A +P +L PAP P+P
Sbjct: 1085 ALEPSATSPLPSPMGDLSCPAPSPAP 1110
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 52.0 bits (123), Expect = 1e-06
Identities = 78/290 (26%), Positives = 111/290 (38%), Gaps = 37/290 (12%)
Query: 159 LEAAIPERVEEIPPEVPT---EPREPERIPVTVLPPEAITI-LEAEPIRMLEIEGERELP 214
L AAI +E P E + E E P V P A + +E P+ + GE
Sbjct: 527 LLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTA 586
Query: 215 EVSRRELDLLIAEEEEAILLEIPRLPPP---APAEVEGIGEALGPEELRLTGWEPGALLM 271
E + + LL A E A PPP APAEV+ P E++ E
Sbjct: 587 EEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP--A 644
Query: 272 EVTPPEELRLPA----PPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRA 327
EV PP PA PP+ E V PPP + ++ + E E+
Sbjct: 645 EVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV-----QSLPAEETPIEETLAAV 699
Query: 328 HCWECPMVQPPERTI---RGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEE 384
H V E ++ PA+L T +G + PPP + PE+
Sbjct: 700 HSPPADDVPAEEASVDKHSPPADLLLTEEFP-------IGEASAEVSPPPS---EQTPED 749
Query: 385 AAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLI 434
A E V +E + P+ A P+V L S+ + EA EE S+I+ +
Sbjct: 750 EALVE-----NVSTEFQSPQVAGIPAVKL-GSVVLEGEAKFEEVSKINSV 793
Score = 50.4 bits (119), Expect = 4e-06
Identities = 95/369 (25%), Positives = 128/369 (34%), Gaps = 88/369 (23%)
Query: 177 EPREPERIPVTVLPP---EAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEE----- 228
EP E+ P + PP EA E P ++ + E E +AE
Sbjct: 258 EPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQ 317
Query: 229 ----EEAILLEIP-RLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPA 283
EEA L+E P + PP+ E + LL E+ PP A
Sbjct: 318 PPPAEEAPLVEFPAEIQPPSAEESPSV-----------------ELLAEILPPS-----A 355
Query: 284 PPSPERRPP---VPPPPRRRRRRRLL--FWDKETQISPEKFQEQLQTRAHCWECPM-VQP 337
SP PP +PPP + LL Q +P + Q L E P V+P
Sbjct: 356 EESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQP-LPAEGALEEAPAKVEP 414
Query: 338 P--ERTI---------RGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAA 386
P E T+ P E R LS + A+ P + LP+E
Sbjct: 415 PTVEETLADVQPLLPEEAPREEARELQLSTAMETP--------AEEAPTEFQSPLPKETT 466
Query: 387 AEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLE--------------AAEEEKSRIS 432
AEE +I++ + E P + +S E S E AEE + I
Sbjct: 467 AEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQ 526
Query: 433 LI-----PPEERWA------WPEVEAPEAPALPVVPELPEVPM-EMPLVL-PPELELLSL 479
L+ P +E A E A EAPA P V + E PL L PP E +
Sbjct: 527 LLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTA 586
Query: 480 EAVHRAVAL 488
E A+ L
Sbjct: 587 EEASAAIQL 595
Score = 48.1 bits (113), Expect = 2e-05
Identities = 83/343 (24%), Positives = 122/343 (35%), Gaps = 40/343 (11%)
Query: 147 PSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLE 206
PS + P + LL +P EE P E P P +LPP A E +E
Sbjct: 336 PSAEESPSVE-LLAEILPPSAEESPSEEP---------PAEILPPPA------EKSPSVE 379
Query: 207 IEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEP 266
+ GE P + +++ E A+ ++ PP E + L PEE P
Sbjct: 380 LLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEA------P 433
Query: 267 GALLMEVTPPEELRLPAPPSP-ERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQT 325
E+ + PA +P E + P+P + T+ P + +
Sbjct: 434 REEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATE--PPADETPAEA 491
Query: 326 RAHCWECPMVQPPERTIRGP-AELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEE 384
R+ E + ++ P AE S + +LL A P + L EE
Sbjct: 492 RSPLSEETSAEEAHAEVQSPLAEETTAEEASAEI--QLLAAIEAPADETPAEAQSPLSEE 549
Query: 385 AAAEEERRKIEVPSEI-----EVPREALEPS----VPLMVSLEISLEAAEE---EKSRIS 432
+AEE +++ PS E P E PS S I L AA E E++
Sbjct: 550 TSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAE 609
Query: 433 LIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELE 475
+ PP A EV+ P A P + P V PP E
Sbjct: 610 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE 652
Score = 42.0 bits (97), Expect = 0.001
Identities = 85/332 (25%), Positives = 128/332 (38%), Gaps = 52/332 (15%)
Query: 213 LPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLME 272
L + R E+ + + +E A+ A AE+E P +++ E E
Sbjct: 230 LEDELREEVTVPVVQEGSAV-------KKVASAEIEPPSTEKFPAKIQPPLVEEATAKAE 282
Query: 273 VTPPEELRLPAPPSPERRP-------------PVPPPPRRRRRRRLLFWDKETQ------ 313
P EE + PS E P V PPP L+ + E Q
Sbjct: 283 PRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPP--AEEAPLVEFPAEIQPPSAEE 340
Query: 314 -ISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLG-LWTHCAQ 371
S E E L A E P +PP + PAE ++P++ ELLG + + AQ
Sbjct: 341 SPSVELLAEILPPSAE--ESPSEEPPAEILPPPAE--KSPSV------ELLGEIRSPSAQ 390
Query: 372 PPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRI 431
P + + LP E A EE K+E P+ +E ++P +P E EA E + S
Sbjct: 391 KAPIEV-QPLPAEGALEEAPAKVEPPT-VEETLADVQPLLPEEAPRE---EARELQLSTA 445
Query: 432 SLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQ 491
P EE A E ++P LP E E+ L+ E A R+ L +
Sbjct: 446 METPAEE--APTEFQSP----LPKETTAEEASAEIQLLAATEPPADETPAEARS-PLSEE 498
Query: 492 ANREPDFSSLVSPLSPRRMAARVFYLLLVLSA 523
+ E + + SPL+ A + +L+A
Sbjct: 499 TSAEEAHAEVQSPLAEETTAEEASAEIQLLAA 530
Score = 41.2 bits (95), Expect = 0.002
Identities = 92/394 (23%), Positives = 134/394 (34%), Gaps = 67/394 (17%)
Query: 139 MMSVDPRLPSPFDIPQIRHL-LEAAIPERVEEIPPE----VPTEPREPE-----RIPVTV 188
+ V P LP + R L L A+ EE P E +P E E ++
Sbjct: 421 LADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAAT 480
Query: 189 LPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPA---PA 245
PP T EA E E EV + AEE A + + + PA PA
Sbjct: 481 EPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPA 540
Query: 246 EVEG-IGEALGPEELRLTGWEPGALLMEVTP-PEELRLPAPPSPERRPPVPPPPRRRRRR 303
E + + E EE P A + + P EL+ PPS E
Sbjct: 541 EAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQ---PPSGE--------------- 582
Query: 304 RLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELL 363
+ + + Q T A E P P PAE+ P P E+
Sbjct: 583 -----ETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEA--PAEV- 634
Query: 364 GLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEA 423
QPPP AEE +++ P E P E ++P E+
Sbjct: 635 -------QPPP------------AEEAPAEVQPPPAEEAPAE-VQPPPAEEAPAEVQPPP 674
Query: 424 AEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVH 483
AEE + + +P EE P E A P ++P + PP LL+ E
Sbjct: 675 AEEAPAEVQSLPAEET---PIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPI 731
Query: 484 RAVALELQ---ANREPDFSSLVSPLSPRRMAARV 514
+ E+ + + P+ +LV +S + +V
Sbjct: 732 GEASAEVSPPPSEQTPEDEALVENVSTEFQSPQV 765
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 49.3 bits (116), Expect = 9e-06
Identities = 75/307 (24%), Positives = 122/307 (39%), Gaps = 44/307 (14%)
Query: 125 MMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERI 184
+ E + AP P FG +S+ P P D+P+ + PPEV P++P
Sbjct: 52 LSEHPKKAPLPEFGAVSLKPPPPEVTDLPK-------------KPPPPEVTDLPKKPPPP 98
Query: 185 PVTVL----PPEAITILEAEPIRMLEIEGERELPEVS-----RRELDLLIAEEEEAILLE 235
VT L PP +T L +P ++ + ++ P++ R+ L + E L
Sbjct: 99 EVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPFPRKPLQPEVGEAPLKASLP 158
Query: 236 IPRLPPPAPAEVEGIGEALGPEELRLTG------WEPGALLMEVTP----PEELRLPAPP 285
P P P + + + P +G W+P A E TP PE P P
Sbjct: 159 EPGAPARKPLQPDELSHPARPPSEPKSGAFPRKLWQPEA--GEATPRSPQPELSTFPKKP 216
Query: 286 SPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGP 345
+ +P P++ + ++ K++ PE F E QT W+ P P+R
Sbjct: 217 A---QPEFNVYPKKPPQPQVGGLPKKSVPQPE-FSEAAQT--PLWK-PQSSEPKRDSSAF 269
Query: 346 AELFRTPTLSGW--LPPE-LLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEV 402
+ P LS + PP+ LG T + P ++ + P A + +K P +
Sbjct: 270 PKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKRPRPAEFKALSKKPPQPELGGL 329
Query: 403 PREALEP 409
PR + EP
Sbjct: 330 PRTSSEP 336
>gi|116686120 periaxin isoform 2 [Homo sapiens]
Length = 1461
Score = 49.3 bits (116), Expect = 9e-06
Identities = 91/358 (25%), Positives = 145/358 (40%), Gaps = 56/358 (15%)
Query: 135 PFFGMMSVDPRLPSPFDIPQIRHLLEAAIPER-VEEIPPEVPTEPREPE----RIPVTVL 189
P FG+ ++PR +P + L +P + PEV P+ PE + P L
Sbjct: 394 PTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKV-PKGPEVKLPKAPEVKL 452
Query: 190 P--PEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEV 247
P PEA +R+ E+E LP+VS +L + + L LP + ++
Sbjct: 453 PKVPEAAL----PEVRLPEVE----LPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKL 504
Query: 248 EGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLF 307
+ E PE +RL P L++V+ + ++P PE R P P+
Sbjct: 505 PKVPEMAVPE-VRL----PEVQLLKVSEMKLPKVPEMAVPEVRLPEVQLPK--------- 550
Query: 308 WDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWT 367
+S K E + P VQ P+ E+ + P + PE+
Sbjct: 551 ------VSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEM-KLPKVPEMKLPEM----- 598
Query: 368 HCAQPPPKALRRELPEEAAAEEERRKIEVPS--EIEVPREALE----PSVPLMVSLEISL 421
P+ ++PE A + ++++P E+++P L P VP M ++ L
Sbjct: 599 ----KLPEVQLPKVPEMAVPDVHLPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHL 654
Query: 422 EAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPE--LPEVP-MEMPLVLPPELEL 476
+ K +P A PEV PE LP V E LP+VP M +P V PE++L
Sbjct: 655 PEVQLPKVPEMKLPKMPEMAVPEVRLPEV-QLPKVSEMKLPKVPEMAVPDVHLPEVQL 711
Score = 47.4 bits (111), Expect = 3e-05
Identities = 87/349 (24%), Positives = 130/349 (37%), Gaps = 51/349 (14%)
Query: 142 VDPRLP-SPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITILEAE 200
V PRLP + +PQ+ A E +PT P P I + + E
Sbjct: 237 VGPRLPGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVE 296
Query: 201 PIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELR 260
+ + LP + RE A+ + +P L AP G+ AL E+
Sbjct: 297 LPALPSLPTLPTLPCLETRE---------GAVSVVVPTLDVAAPTV--GVDLALPGAEVE 345
Query: 261 LTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQ 320
G P L + P PR R + + K ++SPE
Sbjct: 346 ARGEAPEVAL-------------------KMPRLSFPRFGARAKEVAEAKVAKVSPEARV 386
Query: 321 EQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPP------- 373
+ + R + +++P + PT+ +P +G+ + P
Sbjct: 387 KGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIK--MPSLGIGVSGPEVKVPKGPEVKL 444
Query: 374 PKALRRELPE--EAAAEEERRKIEVPSEIEVPR--EALEPSVPLMVSLEISLEAAEEEKS 429
PKA +LP+ EAA E R E+E+P+ E P VP M E+ L E K
Sbjct: 445 PKAPEVKLPKVPEAALPEVRLP-----EVELPKVSEMKLPKVPEMAVPEVRLPEVELPKV 499
Query: 430 RISLIPPEERWAWPEVEAPEAPALPVVP-ELPEVP-MEMPLVLPPELEL 476
+P A PEV PE L V +LP+VP M +P V PE++L
Sbjct: 500 SEMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKVPEMAVPEVRLPEVQL 548
Score = 40.8 bits (94), Expect = 0.003
Identities = 83/334 (24%), Positives = 128/334 (38%), Gaps = 50/334 (14%)
Query: 169 EIP--PEVPTEPREP--------ERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVS- 217
E+P P +PT P P + V L A T+ + E+E E PEV+
Sbjct: 296 ELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPEVAL 355
Query: 218 ---RRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVT 274
R A +E ++ ++ P A + G L L+ EP EV
Sbjct: 356 KMPRLSFPRFGARAKEVAEAKVAKVSPEARVK----GPRLRMPTFGLSLLEPRPAAPEVV 411
Query: 275 PPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPM 334
+L+LP P V P + + + K ++ K E P
Sbjct: 412 E-SKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAA--------LPE 462
Query: 335 VQPPERTIRGPAELFRTPTLSGWLPPEL----LGLWTHCAQPPPKALRRELPEEAAAEEE 390
V+ PE + +E+ + P + PE+ + L PK +PE E +
Sbjct: 463 VRLPEVELPKVSEM-KLPKVPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQ 521
Query: 391 RRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEA 450
K+ SE+++P+ VP M E+ L + K +P A PEV PE
Sbjct: 522 LLKV---SEMKLPK------VPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEV 572
Query: 451 PALPVVPE-------LPEVP-MEMPLVLPPELEL 476
LP VPE LP+VP M++P + PE++L
Sbjct: 573 -QLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQL 605
Score = 40.8 bits (94), Expect = 0.003
Identities = 84/351 (23%), Positives = 139/351 (39%), Gaps = 47/351 (13%)
Query: 144 PRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITILEAEPIR 203
P++P +P++R L E +P+ E P+VP R+P LP + L P
Sbjct: 453 PKVPEAA-LPEVR-LPEVELPKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVP-- 508
Query: 204 MLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVE-------GIGEALGP 256
E +PEV E+ LL E +++P++P A EV + E P
Sbjct: 509 ------EMAVPEVRLPEVQLLKVSE-----MKLPKVPEMAVPEVRLPEVQLPKVSEMKLP 557
Query: 257 E-------ELRLTGWE----PGALLMEVTPPE--ELRLPAPPSPERRPPVPPP---PRRR 300
E E+RL + P + E+ P+ E++LP PE + P P P
Sbjct: 558 EVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVH 617
Query: 301 RRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPP 360
L E ++ K E + P V PE + E+ + P + P
Sbjct: 618 LPEVQLPKVPEMKLPEMKLPEVKLPKVPEMAVPDVHLPEVQLPKVPEM-KLPKMPEMAVP 676
Query: 361 ELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPS--EIEVPREALE----PSVPLM 414
E+ + L + +PE A + ++++P E++VP L P VP M
Sbjct: 677 EVRLPEVQLPKVSEMKLPK-VPEMAVPDVHLPEVQLPKVCEMKVPDMKLPEIKLPKVPEM 735
Query: 415 VSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPME 465
++ L + K +P + P+V P+AP + +P PEV ++
Sbjct: 736 AVPDVHLPEVQLPKVSEIRLPEMQVPKVPDVHLPKAPEVK-LPRAPEVQLK 785
>gi|222136644 RAD21-like 1 [Homo sapiens]
Length = 556
Score = 48.5 bits (114), Expect = 2e-05
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 3 YYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPR 62
+Y +VL G A IWLAA +L K N+ T E+IL+ P+
Sbjct: 2 FYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIEKILS-------------PK 48
Query: 63 PRFSLYLSAQLQIGVIRVYSQQCQYLVED 91
+ +L S L +GV+R+Y+++ +YL+ D
Sbjct: 49 VKIALRTSGHLLLGVVRIYNRKAKYLLAD 77
Score = 36.2 bits (82), Expect = 0.079
Identities = 58/267 (21%), Positives = 105/267 (39%), Gaps = 20/267 (7%)
Query: 298 RRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTI-----RGPAELFRTP 352
R+ ++RRLL D ++S + +QL + A + PP + + RG +
Sbjct: 291 RKGKKRRLLI-DPIKELSSKVIHKQLTSFADTLMVLELAPPTQRLMMWKKRGGVHTLLST 349
Query: 353 TLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEE--RRKIEVPSEIEVPREALEPS 410
+ EL L+T C L R++ ++ + EE + I S ++ P E S
Sbjct: 350 AAQDLIHAELKMLFTKCFLSSGFKLGRKMIQKESVREEVGNQNIVETSMMQEPNYQQELS 409
Query: 411 VPLMVSLEIS-LEAAEEEKSRISLIPPEERWAWPEVEAPEAPALP--VVPELPEVPMEMP 467
P I + + E + ++ ++ + A E+ + E+ P+E+
Sbjct: 410 KPQTWKDVIGGSQHSSHEDTNKNINSEQDIVEMVSLAAEESSLMNDLFAQEIEYSPVELE 469
Query: 468 LVLPPELELLSLEAVHRAVALELQANREPDFSSLVS-------PLSPRRMAARVFYLLLV 520
+ E + E + + L RE + + S S R+ AA FY LV
Sbjct: 470 SL--SNEENIETERWNGRILQMLNRLRESNKMGMQSFSLMKLCRNSDRKQAAAKFYSFLV 527
Query: 521 LSAQQILHVKQEKPYGRLLIQPGPRFH 547
L Q + + Q PY ++ GP F+
Sbjct: 528 LKKQLAIELSQSAPYADIIATMGPMFY 554
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 45.4 bits (106), Expect = 1e-04
Identities = 97/384 (25%), Positives = 126/384 (32%), Gaps = 66/384 (17%)
Query: 206 EIEGERELPEVSRREL--DLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTG 263
E E ++E E R + +++ A E+E L P L PPAP+ P L
Sbjct: 371 EEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSP---------PPPLPPPS 421
Query: 264 WEPGALLMEVTPP--EELRLPAPPSP-------ERRPPVPPPPRRRRRRRLLFWDKETQ- 313
P L PP LP+PP P E PPV P R+R R +
Sbjct: 422 TSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAE 481
Query: 314 ----------ISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELL 363
SP T + P V P T F P +S +
Sbjct: 482 REAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIK 541
Query: 364 GLWTHCAQPPPKALRREL------PEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSL 417
+ PPK + E+ P + + VPS PR PS P+ +
Sbjct: 542 TPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSP---PRAPTPPSTPVPLP- 597
Query: 418 EISLEAAEEEKSRISLIPPEERWAW------PEVEAPEAPALPVVPELPEVPMEMPLVL- 470
EK R L P RW P AP P P P P PL+L
Sbjct: 598 ---------EKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLR 648
Query: 471 -----PPELELLSLEAVHRAVALELQANREPDFSSL-VSPLSPR-RMAARVFYLLLVLSA 523
P E L E+V L EP+ SP P R R +L L A
Sbjct: 649 APQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFA 708
Query: 524 QQI-LHVKQE-KPYGRLLIQPGPR 545
+ VK E P+G + GP+
Sbjct: 709 PVVTTPVKAEVSPHGAPALSNGPQ 732
Score = 37.0 bits (84), Expect = 0.047
Identities = 46/176 (26%), Positives = 61/176 (34%), Gaps = 25/176 (14%)
Query: 134 DPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEA 193
+P F S+ LP P P P PP T R P + P
Sbjct: 606 EPTFRWTSLTRELPPPPPAPP---------PPPAPSPPPAPATSSRRPLLLRAPQFTPSE 656
Query: 194 ITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAIL-----LEIPRLPP----PAP 244
+ E + G E PE D AE E + L +PR P P
Sbjct: 657 AHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVK 716
Query: 245 AEVEGIGEAL---GPEE----LRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPV 293
AEV G GP+ L+ LL + PP + +L PPSP++ PP+
Sbjct: 717 AEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPL 772
Score = 32.3 bits (72), Expect = 1.1
Identities = 65/254 (25%), Positives = 85/254 (33%), Gaps = 55/254 (21%)
Query: 140 MSVDPRLPSPFDI-PQIRHLLEAAIPERVEEIP----PEVPTEPREPERIPVTVLPPEAI 194
M DP P ++ P +R + + P E P P PT P P +P LP +
Sbjct: 547 MDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP--VP---LPEKRR 601
Query: 195 TILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEAL 254
+IL R + RELP P PPP PA A
Sbjct: 602 SILREPTFRWTSL--TRELPPP--------------------PPAPPPPPAPSPPPAPAT 639
Query: 255 G---PEELRLTGWEPGALLMEV-----TPPEELRLPAPPSPERRP----PVPPPPRRRRR 302
P LR + P +++ TPP L P P PE P P P PR R
Sbjct: 640 SSRRPLLLRAPQFTPSEAHLKIYESVLTPP-PLGAPEAPEPEPPPADDSPAEPEPRAVGR 698
Query: 303 RRLLFWDKETQI--SPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPP 360
L + + +P K + P Q + P + +T L LPP
Sbjct: 699 TNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQ---AQLLQPLQALQTQLLPQALPP 755
Query: 361 ELLGLWTHCAQPPP 374
L QPPP
Sbjct: 756 PQPQL-----QPPP 764
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/157 (29%), Positives = 59/157 (37%), Gaps = 31/157 (19%)
Query: 265 EPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQ 324
E L+ + LR P P +P + PPPRR RR + P +L
Sbjct: 8 ETTVLMSQTEADLALRPPPPLGTAGQPRLGPPPRRARR-------FSGKAEPRPRSSRLS 60
Query: 325 TRA-------HCWECPM------VQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQ 371
R+ W P PP+ GPA R+P S PPE G WT A
Sbjct: 61 RRSSVDLGLLSSWSLPASPAPDPPDPPDSAGPGPA---RSPPPSSKEPPE--GTWTEGA- 114
Query: 372 PPPKA----LRRELPEEAAAEEERRKIEVPSEIEVPR 404
P KA R ELP+ A R + VP + + R
Sbjct: 115 -PVKAAEDSARPELPDSAVGPGSREPLRVPEAVALER 150
>gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
Length = 985
Score = 43.1 bits (100), Expect = 6e-04
Identities = 66/268 (24%), Positives = 95/268 (35%), Gaps = 60/268 (22%)
Query: 164 PERVEEIPPEVPTEPREPERIPV--TVLPPEAITILEAEPIRMLEIEGERELPEVSRREL 221
P R PP +P +P P + PV + P A + + P+ + P +
Sbjct: 277 PRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQP 336
Query: 222 DLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRL 281
++ E RLP P LGP LR +PGA + ++
Sbjct: 337 PMMTCE----------RLPCPTAG--------LGP--LREEAMKPGAASSPLQ-----QV 371
Query: 282 PAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERT 341
PAPP P ++ PPRRR R+ D+ ++ E Q L PP+ T
Sbjct: 372 PAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSL-------------PPQGT 418
Query: 342 IRGPAELFRTPTLSG----------WLPPELLGLWTHCAQPPP--KALRRELPEEAAAEE 389
GP + R T G PEL PPP K + R+L A
Sbjct: 419 SDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPL 478
Query: 390 ERRK-------IEVPSEIEVPREALEPS 410
E + +E P+ PRE P+
Sbjct: 479 ENAELCTQAMALETPTP-GPPREGQSPA 505
>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
Length = 1035
Score = 43.1 bits (100), Expect = 6e-04
Identities = 59/210 (28%), Positives = 81/210 (38%), Gaps = 15/210 (7%)
Query: 338 PERTIRGPAELFRTP--TLSGWLPPEL--LGLWTHCAQPPPKALR--RELPEEAAAEE-- 389
PE + G + L P TL L PE G+ C +PP + R+LP EA
Sbjct: 320 PEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLC 379
Query: 390 -ERRKIEVPS-EIEVPREALEPSVPLMVSLEISLEAAEEEK---SRISLIPPEERWAWPE 444
E K VP E P+ + P P IS +E K S + L PP+ R +
Sbjct: 380 PEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLR 439
Query: 445 VEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQANREPDFSSLVSP 504
E PE + PE P+ + + PPE + L + PD VS
Sbjct: 440 PEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTG--VSH 497
Query: 505 LSPRRMAARVFYLLLVLSAQQILHVKQEKP 534
L P RV +L S + H++ E P
Sbjct: 498 LCPEPPKTRVSHLRPEPSETGVSHLRPEPP 527
Score = 40.0 bits (92), Expect = 0.006
Identities = 103/422 (24%), Positives = 150/422 (35%), Gaps = 86/422 (20%)
Query: 155 IRHLLEAAIPERVEEI---PPE--VPTEPREPERIPVTVLPPE----AITILEAEPIRML 205
+ HL RV + PPE VP EP + V+ L PE ++ L EP + L
Sbjct: 279 VSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTL 338
Query: 206 EIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWE 265
E PE + L E E + + +LPP A G+ L PE
Sbjct: 339 VSSLHPEPPETG---VSHLCPEPPETRVSPLRQLPPEA-----GVSH-LCPE-------- 381
Query: 266 PGALLMEVTPPEELRLPA--PPSPER--RPPVPPPPRRRRRRRLLFWDKETQISPEKFQE 321
P + R+P P +P+ P P PP+ T+IS + +
Sbjct: 382 ----------PPKTRVPPLRPETPKNGVSPLFPEPPK-------------TRISNLRSEP 418
Query: 322 QLQTRAH-CWECPMV-------QPPERTIRG-PAELFRTPTLSGWLPPELLGLWTHCAQP 372
+H C E P +PPE + E +T S L P G+ C +P
Sbjct: 419 PKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEP 478
Query: 373 PPKA---LRRELPEEAAAE--EERRKIEV----PSEIEVPREALEPSVPLMVSLEISLEA 423
P K LR E P+ + E K V P E L P P ++ +
Sbjct: 479 PEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAP 538
Query: 424 AEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVH 483
E S + PPE + E P+ + PE P+ + PP+ + SL
Sbjct: 539 PESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPP-- 596
Query: 484 RAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLL-IQP 542
EP + VS L P RV +L + H++ E P R+ ++P
Sbjct: 597 -----------EPPETG-VSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRP 644
Query: 543 GP 544
P
Sbjct: 645 EP 646
Score = 33.1 bits (74), Expect = 0.67
Identities = 118/497 (23%), Positives = 171/497 (34%), Gaps = 105/497 (21%)
Query: 111 ETELPSLLLPNHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEI 170
ET +P L L + + L P G+ + P P + L+ + PE E
Sbjct: 300 ETGVPDLCLEPPKSRVSHLRPEPSET-GVSHLHPEPP--------KTLVSSLHPEPPETG 350
Query: 171 PPEVPTEPREPERIPVTVLPPEA-ITILEAEP----IRMLEIEGERE-----LPEVSRRE 220
+ EP E P+ LPPEA ++ L EP + L E + PE +
Sbjct: 351 VSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTR 410
Query: 221 LDLLIAEEEEAILLEIPRLPP--------PAPAEVEGIGEALGPE-------ELRLTGWE 265
+ L +E + + + PP P P E G+ L PE L L E
Sbjct: 411 ISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPET-GVSH-LRPEPPKTRVSSLHLEPPE 468
Query: 266 PGALLMEVTPPEE----LRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQIS------ 315
G + PPE+ LR P PP P PP+ R L ET +S
Sbjct: 469 TGVSHLCPEPPEKDVSHLR-PEPPDTGVSHLCPEPPKTRVSH-LRPEPSETGVSHLRPEP 526
Query: 316 ------------PEKFQEQLQTRAHCWECPMVQP-----------PERTIRGPAELFRTP 352
PE L+ ++P PE G + L P
Sbjct: 527 PKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEP 586
Query: 353 --TLSGWLPPEL--LGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALE 408
T LPPE G+ C +PP + PE + E P + +L
Sbjct: 587 PKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPP---KTRMYSLR 643
Query: 409 PSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPL 468
P P + +S E K+R+S +PPE PE + PE PE +
Sbjct: 644 PEPP---NTGVSHLCPEPPKTRVSSLPPEP---------PETGVSHLCPEPPETRVSHLR 691
Query: 469 VLPPELELLSLEAVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILH 528
PPE + L + EP + VS L +RV +L + H
Sbjct: 692 PEPPETGVSRL-------------HPEPP-KTRVSSLHAEPPESRVSHLCPEPPETGVSH 737
Query: 529 VKQEKPYGRL-LIQPGP 544
++ E P R+ ++P P
Sbjct: 738 LRPEPPKPRVSSLRPEP 754
Score = 32.3 bits (72), Expect = 1.1
Identities = 73/293 (24%), Positives = 103/293 (35%), Gaps = 35/293 (11%)
Query: 214 PEVSRRELDLLIAEEEEAILLEIPRLPP--------PAPAEVEGIGEALGPEELRLTGWE 265
PE S + L E + ++ + + PP P P E P + R+
Sbjct: 512 PEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLR 571
Query: 266 P-----GALLMEVTPPEELRLPAPPSPERR--PPVPPPPRRRRRRRLLFWDKETQISPEK 318
P G + PP+ PP P + P P R L ET +S +
Sbjct: 572 PEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLR 631
Query: 319 FQEQLQTRAHCWECPMVQPPERTIRGPAELFRTP--TLSGWLPPEL--LGLWTHCAQPPP 374
E +TR + PE G + L P T LPPE G+ C +PP
Sbjct: 632 -PEPPKTRMYSLR------PEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPE 684
Query: 375 KA---LRRELPEEAAAE--EERRKIEVPS-EIEVPREALEPSVPLMVSLEISLEAAEEEK 428
LR E PE + E K V S E P + P +S E K
Sbjct: 685 TRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPK 744
Query: 429 SRISLIPPEE---RWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLS 478
R+S + PE R + E PE + PELP+ + + PP+ +S
Sbjct: 745 PRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVS 797
>gi|209529739 hypothetical protein LOC100132247 [Homo sapiens]
Length = 1133
Score = 42.7 bits (99), Expect = 8e-04
Identities = 68/263 (25%), Positives = 97/263 (36%), Gaps = 54/263 (20%)
Query: 239 LPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPE---RRPP--- 292
LPP A ++ P E LT P A TPPE L P PPS + + PP
Sbjct: 293 LPPSADDNLKT------PPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECL 346
Query: 293 -VPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRT 351
P PP +P + L+TRA C P+ + ++ P+E T
Sbjct: 347 LTPLPP------------SALPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSERQLT 394
Query: 352 PTLSGWLPPELLGLWTHCAQPPPKALRRELPEEA----AAEEERRKIEVP--------SE 399
P LPP + P + LR LP A ER+ +P
Sbjct: 395 P-----LPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDN 449
Query: 400 IEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPP------EERWAWPEVEAPEAPAL 453
I+ P E L PL S + +L+ E +++ +PP ++ P E P
Sbjct: 450 IKTPAERLRG--PLPPSADDNLKTPSER--QLTPLPPSAPPSADDNIKTP-AERLRGPLP 504
Query: 454 PVVPELPEVPMEMPL-VLPPELE 475
P + + P E L LPP +
Sbjct: 505 PSADDNLKTPSERQLTALPPSAD 527
Score = 35.4 bits (80), Expect = 0.14
Identities = 42/146 (28%), Positives = 53/146 (36%), Gaps = 20/146 (13%)
Query: 170 IPPEVPTEPREPERIPVTVLPPEAITILE------AEPIR-MLEIEGERELPEVSRRELD 222
+PP + P +T LPP A + AE +R L + L S R+L
Sbjct: 419 LPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLT 478
Query: 223 LLIAEE----EEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEE 278
L ++ I RL P P + P E +LT P A TP E
Sbjct: 479 PLPPSAPPSADDNIKTPAERLRGPLPPSADD--NLKTPSERQLTALPPSADDNIKTPAER 536
Query: 279 LRLPAPPS-------PERRPPVPPPP 297
LR P PPS P R P PP
Sbjct: 537 LRGPLPPSADDNLKTPSERQLTPLPP 562
Score = 33.9 bits (76), Expect = 0.39
Identities = 33/127 (25%), Positives = 44/127 (34%), Gaps = 22/127 (17%)
Query: 241 PPAPAEVEGIGE----ALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPP 296
PP P + I + P E LT P A TPPE + P PPS + PP
Sbjct: 247 PPPPTQQHSITDNSLSLKTPPECLLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPP- 305
Query: 297 PRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSG 356
+ P + L+T C P+ + ++ P E TP
Sbjct: 306 ------------ECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTP---- 349
Query: 357 WLPPELL 363
LPP L
Sbjct: 350 -LPPSAL 355
Score = 33.5 bits (75), Expect = 0.51
Identities = 53/213 (24%), Positives = 75/213 (35%), Gaps = 40/213 (18%)
Query: 117 LLLPNHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVE-EIPPEVP 175
+++ HL + +L P M + LPS ER+ +PP
Sbjct: 833 MIISRHLPSVSSLPFHPQLHPQQMIISRHLPS-------------VCGERLRGPLPPSAD 879
Query: 176 TEPREPERIPVTVLPPEAITILE------AEPIR-MLEIEGERELPEVSRRELDLLIAEE 228
+ P +T LPP A + AE +R L + L S R+L L
Sbjct: 880 DNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSA 939
Query: 229 ----EEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLME----VTPPEELR 280
++ I RL P P + P E +LT P A TP E LR
Sbjct: 940 PPSADDNIKTPAERLRGPLPPSADD--NLKTPSERQLTPLPPSAPPSADDNIKTPAERLR 997
Query: 281 LPAPPSPERRPPVPP---------PPRRRRRRR 304
P PPS + PP PR+ +R+R
Sbjct: 998 GPLPPSADDNLKTPPLATQEAEAEKPRKPKRQR 1030
Score = 32.0 bits (71), Expect = 1.5
Identities = 59/241 (24%), Positives = 81/241 (33%), Gaps = 34/241 (14%)
Query: 170 IPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEE 229
+PP + P +T LPP A + ++ ER + D L E
Sbjct: 916 LPPSADDNLKTPSERQLTPLPPSAPPSADDN----IKTPAERLRGPLPPSADDNLKTPSE 971
Query: 230 EAILLEIPRLPPPAPAEVEGIGEAL-GPEELRLTGWEPGALLMEVTPP-----EELRLPA 283
+ P PP A ++ E L GP P A TPP E P
Sbjct: 972 RQLTPLPPSAPPSADDNIKTPAERLRGP-------LPPSADDNLKTPPLATQEAEAEKPR 1024
Query: 284 PPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIR 343
P +R + PPP +RRR D E P++ RA E P P+R
Sbjct: 1025 KPKRQRAAEMEPPPEPKRRR---VGDVEPSRKPKR------RRAADVE-PSSPEPKRRRV 1074
Query: 344 GPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVP 403
G E R P E + P PK R E + + RR +V + P
Sbjct: 1075 GDVEPSRKPKRRRAADVE-------PSSPEPKRRRVGDVEPSRKPKRRRAADVEPSLPEP 1127
Query: 404 R 404
+
Sbjct: 1128 K 1128
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 42.7 bits (99), Expect = 8e-04
Identities = 94/389 (24%), Positives = 140/389 (35%), Gaps = 84/389 (21%)
Query: 112 TELPSLLLPNH-LAMMETLEDAPDPFFGMMSVDPRLPS-PFDIPQIRHLLEAAIPERVEE 169
TE PS+ ++M ET+ P ++ P P+ P + P IP
Sbjct: 686 TEKPSIPTEKPTISMEETIISTEKP-----TISPEKPTIPTEKP--------TIPTEKST 732
Query: 170 IPPEVPTEPREPERIPV---TVLP-------------PEAITILEAEPIRMLEIEG-ERE 212
I PE PT P E IP T+ P PE +TI +P E E
Sbjct: 733 ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTE 792
Query: 213 LPEVSRRE-----LDLLIAEEEEAILLEIPRLP-PPAPAEVEGIGEALGPEELRLTGWEP 266
P +S E + I+ E+ +I +E P LP VE + E+L + +P
Sbjct: 793 KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVE--ETTISTEKLTIPMEKP 850
Query: 267 GALLMEVT--------PPEELRLPAP--PSPERRPPVPPPPRRRRRRRLLFWDKETQISP 316
+ T PE+L +P P +P +P +L ++ ISP
Sbjct: 851 TISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISP 910
Query: 317 EKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKA 376
EK + E P + E TI E PT + PE L + T +P
Sbjct: 911 EKPTISTEKPTIPTEKPTIPTEETTI--STEKLTIPTEKPTISPEKLTIPTE--KPTIST 966
Query: 377 LRRELPEEAAAEEERRKIEVPSE-IEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIP 435
+ +P E K+ +P+E +P E +P++P + +L P
Sbjct: 967 EKPTIPTE--------KLTIPTEKPTIPTE--KPTIP--------------TEKLTALRP 1002
Query: 436 PEERWAWPEVEAPEAPALPVVPELPEVPM 464
P P A AL + P P PM
Sbjct: 1003 PH-----PSPTATGLAALVMSPHAPSTPM 1026
Score = 36.6 bits (83), Expect = 0.061
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 39/347 (11%)
Query: 160 EAAIPERVEEIPPEVPTEPREPERIPV--TVLPPEAITILEAEPIRMLE-----IEGERE 212
E IP IP E P+ P E I + T++ E TI +P E E
Sbjct: 674 EPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTI 733
Query: 213 LPEVSRRELDL-LIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLM 271
PE + I E+ I E P P P + PE+L + +P
Sbjct: 734 SPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKP--------TISPEKLTIPTEKPTIPTE 785
Query: 272 EVTPPEE-----LRLPAPPSPE-----RRPPVPPPPRRRRRRRLLFWDKETQISPEKFQE 321
+ T P E P P+ E +P +P +ET IS EK
Sbjct: 786 KPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTI 845
Query: 322 QLQTRAHCWECPMVQPPERTIRG-----PAELFRTPTLSGWLPPELLGLWTHCAQPPPKA 376
++ E P + + TI P E PT +P E + T P +
Sbjct: 846 PMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEK 905
Query: 377 LRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPP 436
PE+ E+ I E P E + L I E +++ IP
Sbjct: 906 PTIS-PEKPTISTEKPTIPT----EKPTIPTEETTISTEKLTIPTEKPTISPEKLT-IPT 959
Query: 437 EERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVH 483
E+ E L + E P +P E P + P +L +L H
Sbjct: 960 EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTI--PTEKLTALRPPH 1004
Score = 33.5 bits (75), Expect = 0.51
Identities = 58/260 (22%), Positives = 95/260 (36%), Gaps = 42/260 (16%)
Query: 236 IPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPP 295
+P LPP +P G E G E + + +E + P P+ +P +P
Sbjct: 539 LPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIE---KPSVTTEKPTVPKEKPTIPT 595
Query: 296 PPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLS 355
+ ++ + EK + E P + + TI P+E PT+S
Sbjct: 596 EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI--PSE---KPTIS 650
Query: 356 GWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPL-- 413
P + T P + + E E K +P+E +PS+P
Sbjct: 651 TEKPT----VPTEEPTTPTEETTTSMEEPVIPTE---KPSIPTE--------KPSIPTEK 695
Query: 414 -MVSLEISLEAAEE-----EKSRI----SLIPPEERWAWPE--VEAPEAPALP-----VV 456
+S+E ++ + E+ EK I IP E+ PE E P +P +
Sbjct: 696 PTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTIS 755
Query: 457 PELPEVPMEMPLVLPPELEL 476
PE P P E P + P +L +
Sbjct: 756 PEKPTTPTEKPTISPEKLTI 775
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 42.7 bits (99), Expect = 8e-04
Identities = 94/389 (24%), Positives = 140/389 (35%), Gaps = 84/389 (21%)
Query: 112 TELPSLLLPNH-LAMMETLEDAPDPFFGMMSVDPRLPS-PFDIPQIRHLLEAAIPERVEE 169
TE PS+ ++M ET+ P ++ P P+ P + P IP
Sbjct: 686 TEKPSIPTEKPTISMEETIISTEKP-----TISPEKPTIPTEKP--------TIPTEKST 732
Query: 170 IPPEVPTEPREPERIPV---TVLP-------------PEAITILEAEPIRMLEIEG-ERE 212
I PE PT P E IP T+ P PE +TI +P E E
Sbjct: 733 ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTE 792
Query: 213 LPEVSRRE-----LDLLIAEEEEAILLEIPRLP-PPAPAEVEGIGEALGPEELRLTGWEP 266
P +S E + I+ E+ +I +E P LP VE + E+L + +P
Sbjct: 793 KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVE--ETTISTEKLTIPMEKP 850
Query: 267 GALLMEVT--------PPEELRLPAP--PSPERRPPVPPPPRRRRRRRLLFWDKETQISP 316
+ T PE+L +P P +P +P +L ++ ISP
Sbjct: 851 TISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISP 910
Query: 317 EKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKA 376
EK + E P + E TI E PT + PE L + T +P
Sbjct: 911 EKPTISTEKPTIPTEKPTIPTEETTI--STEKLTIPTEKPTISPEKLTIPTE--KPTIST 966
Query: 377 LRRELPEEAAAEEERRKIEVPSE-IEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIP 435
+ +P E K+ +P+E +P E +P++P + +L P
Sbjct: 967 EKPTIPTE--------KLTIPTEKPTIPTE--KPTIP--------------TEKLTALRP 1002
Query: 436 PEERWAWPEVEAPEAPALPVVPELPEVPM 464
P P A AL + P P PM
Sbjct: 1003 PH-----PSPTATGLAALVMSPHAPSTPM 1026
Score = 36.6 bits (83), Expect = 0.061
Identities = 80/347 (23%), Positives = 115/347 (33%), Gaps = 39/347 (11%)
Query: 160 EAAIPERVEEIPPEVPTEPREPERIPV--TVLPPEAITILEAEPIRMLE-----IEGERE 212
E IP IP E P+ P E I + T++ E TI +P E E
Sbjct: 674 EPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTI 733
Query: 213 LPEVSRRELDL-LIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLM 271
PE + I E+ I E P P P + PE+L + +P
Sbjct: 734 SPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKP--------TISPEKLTIPTEKPTIPTE 785
Query: 272 EVTPPEE-----LRLPAPPSPE-----RRPPVPPPPRRRRRRRLLFWDKETQISPEKFQE 321
+ T P E P P+ E +P +P +ET IS EK
Sbjct: 786 KPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTI 845
Query: 322 QLQTRAHCWECPMVQPPERTIRG-----PAELFRTPTLSGWLPPELLGLWTHCAQPPPKA 376
++ E P + + TI P E PT +P E + T P +
Sbjct: 846 PMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEK 905
Query: 377 LRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPP 436
PE+ E+ I E P E + L I E +++ IP
Sbjct: 906 PTIS-PEKPTISTEKPTIPT----EKPTIPTEETTISTEKLTIPTEKPTISPEKLT-IPT 959
Query: 437 EERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVH 483
E+ E L + E P +P E P + P +L +L H
Sbjct: 960 EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTI--PTEKLTALRPPH 1004
Score = 33.5 bits (75), Expect = 0.51
Identities = 58/260 (22%), Positives = 95/260 (36%), Gaps = 42/260 (16%)
Query: 236 IPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPP 295
+P LPP +P G E G E + + +E + P P+ +P +P
Sbjct: 539 LPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIE---KPSVTTEKPTVPKEKPTIPT 595
Query: 296 PPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLS 355
+ ++ + EK + E P + + TI P+E PT+S
Sbjct: 596 EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI--PSE---KPTIS 650
Query: 356 GWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPL-- 413
P + T P + + E E K +P+E +PS+P
Sbjct: 651 TEKPT----VPTEEPTTPTEETTTSMEEPVIPTE---KPSIPTE--------KPSIPTEK 695
Query: 414 -MVSLEISLEAAEE-----EKSRI----SLIPPEERWAWPE--VEAPEAPALP-----VV 456
+S+E ++ + E+ EK I IP E+ PE E P +P +
Sbjct: 696 PTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTIS 755
Query: 457 PELPEVPMEMPLVLPPELEL 476
PE P P E P + P +L +
Sbjct: 756 PEKPTTPTEKPTISPEKLTI 775
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 42.4 bits (98), Expect = 0.001
Identities = 64/256 (25%), Positives = 91/256 (35%), Gaps = 45/256 (17%)
Query: 129 LEDAPDPFFGMMS--VDPRLP-SPFDIPQIRHLLEAAIPERVEEIPPEVPTEPRE--PER 183
++ +P PF ++P+LP S FD I H + + E+PP +P P P
Sbjct: 793 MKSSPPPFIATQVPVLEPQLPGSVFD--PIGHFTQPILHLPQPELPPHLPQPPEHSTPPH 850
Query: 184 IP--VTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPP 241
+ V PP L +P R LP R + A + +L + P P
Sbjct: 851 LNQHAVVSPPALHNALPQQPSR--PSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQP 908
Query: 242 PAPAEVEGIGEALGPEELRLTGWEPGALLME---VTPPEELRLPAPPSPERRPPVPPPPR 298
P + + E P LT + L + V PP L + PP+PPPP
Sbjct: 909 P-----QVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH 963
Query: 299 RRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWL 358
Q+QLQ + P QPP P + + P L
Sbjct: 964 ------------------PSVQQQLQQQPPPPPPPQPQPP------PQQQHQPPPRPVHL 999
Query: 359 PPELLGLWTHCAQPPP 374
P + TH QPPP
Sbjct: 1000 QP--MQFSTHIQQPPP 1013
Score = 38.5 bits (88), Expect = 0.016
Identities = 50/217 (23%), Positives = 78/217 (35%), Gaps = 35/217 (16%)
Query: 275 PPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPM 334
PP++ P PP +++PP PPPP ++ + SP F + P+
Sbjct: 760 PPQQPPPPPPPQQQQQPPPPPPPPSMPQQAA----PAMKSSPPPF--------IATQVPV 807
Query: 335 VQPP-ERTIRGPAELFRTPTL---SGWLPPELLGLWTHCAQP--------PPKALRRELP 382
++P ++ P F P L LPP L H P P AL LP
Sbjct: 808 LEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALP 867
Query: 383 EEAAAEEERRKIEVPSEIEVP-------REALEPSVPLMVSLEISLEAAEEEKSRISLIP 435
++ + R P P + L P P+ ++ LE E ++ +
Sbjct: 868 QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927
Query: 436 PEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPP 472
+ + P P LP V +V + P LPP
Sbjct: 928 MQLYLQQLQKVQPPTPLLPSV----KVQSQPPPPLPP 960
Score = 38.1 bits (87), Expect = 0.021
Identities = 42/185 (22%), Positives = 67/185 (36%), Gaps = 34/185 (18%)
Query: 284 PPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIR 343
PP P ++PP PPPP+++++ P +Q P ++
Sbjct: 757 PPPPPQQPPPPPPPQQQQQ-------PPPPPPPPSMPQQ------------AAPAMKSSP 797
Query: 344 GPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVP 403
P + P L LP + H QP + ELP + P E P
Sbjct: 798 PPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPH---------LPQPPEHSTP 848
Query: 404 REALEPSVPLMVSLEISL-EAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEV 462
+ +V +L +L + +R + +PP+ P +PAL P LP+
Sbjct: 849 PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPK-----PARPPAVSPALTQTPLLPQP 903
Query: 463 PMEMP 467
PM P
Sbjct: 904 PMAQP 908
Score = 32.0 bits (71), Expect = 1.5
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 270 LMEVTPPEELRLPAPPSPERRPPVPPPPR 298
+M V PP+ L+ P P P+ +PP P P+
Sbjct: 238 VMTVVPPQPLQTPPPVPPQPQPPPAPAPQ 266
Score = 32.0 bits (71), Expect = 1.5
Identities = 72/346 (20%), Positives = 121/346 (34%), Gaps = 80/346 (23%)
Query: 147 PSPFDIPQIRHLLEAA--IPERVEEIPPEVPTEPREPERIPVT-------------VLPP 191
P P P + L +P+ PP+V E EP P+T V PP
Sbjct: 882 PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
Query: 192 EAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIG 251
+ P ++ + LP + + ++ P PPP P
Sbjct: 942 TPLL-----PSVKVQSQPPPPLPPPPHPSVQQQLQQQP-------PPPPPPQPQPPPQQQ 989
Query: 252 EALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKE 311
P + L + + + PP+ + P PP P ++PP P P + ++ +
Sbjct: 990 HQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPP-PGQQPPPPQPAKPQQ-------VIQ 1041
Query: 312 TQISPEKFQEQLQTRAHCWECP---MVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTH 368
SP + + H E P M+ P ++ + +L+ PP+
Sbjct: 1042 HHHSPRHHKSDPYSTGHLREAPSPLMIHSP--------QMSQFQSLTHQSPPQ------Q 1087
Query: 369 CAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEK 428
QP + LR AA+ + + + V E ++ + S P SL
Sbjct: 1088 NVQPKKQELR------AASVVQPQPLVVVKEEKIHSPIIR-SEPFSPSLRPE-------- 1132
Query: 429 SRISLIPPEERWAWPEVEAPEAPA-LPVVPELPEVPMEMPLVLPPE 473
PP+ E+ +AP LP PE+ V + P++ PPE
Sbjct: 1133 ------PPK------HPESIKAPVHLPQRPEMKPVDVGRPVIRPPE 1166
>gi|157074225 nuclear pore complex interacting protein-like 3 [Homo
sapiens]
Length = 678
Score = 42.4 bits (98), Expect = 0.001
Identities = 58/217 (26%), Positives = 82/217 (37%), Gaps = 46/217 (21%)
Query: 239 LPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPE---RRPP--- 292
LPP A ++ P E LT P A TPPE L P PPS + + PP
Sbjct: 293 LPPSADDNLKT------PPECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECL 346
Query: 293 -VPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRT 351
P PP +P + L+TRA C P+ + ++ P+E T
Sbjct: 347 LTPLPP------------SALPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSERQLT 394
Query: 352 PTLSGWLPPELLGLWTHCAQPPPKALRRELPEEA----AAEEERRKIEVP--------SE 399
P LPP + P + LR LP A ER+ +P
Sbjct: 395 P-----LPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDN 449
Query: 400 IEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPP 436
I+ P E L PL S + +L+ E +++ +PP
Sbjct: 450 IKTPAERLRG--PLPPSADDNLKTPSER--QLTPLPP 482
Score = 33.9 bits (76), Expect = 0.39
Identities = 33/127 (25%), Positives = 44/127 (34%), Gaps = 22/127 (17%)
Query: 241 PPAPAEVEGIGE----ALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPP 296
PP P + I + P E LT P A TPPE + P PPS + PP
Sbjct: 247 PPPPTQQHSITDNSLSLKTPPECLLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPP- 305
Query: 297 PRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSG 356
+ P + L+T C P+ + ++ P E TP
Sbjct: 306 ------------ECVLTPLPPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTP---- 349
Query: 357 WLPPELL 363
LPP L
Sbjct: 350 -LPPSAL 355
Score = 32.7 bits (73), Expect = 0.88
Identities = 43/159 (27%), Positives = 58/159 (36%), Gaps = 26/159 (16%)
Query: 170 IPPEVPTEPREPERIPVTVLPPEAITILE------AEPIR-MLEIEGERELPEVSRRELD 222
+PP + P +T LPP A + AE +R L + L S R+L
Sbjct: 419 LPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLT 478
Query: 223 LLIAEE----EEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLME----VT 274
L ++ I RL P P + P E +LT P A T
Sbjct: 479 PLPPSAPPSADDNIKTPAERLRGPLPPSADD--NLKTPSERQLTPLPPSAPPSADDNIKT 536
Query: 275 PPEELRLPAPPSPERRPPVPP---------PPRRRRRRR 304
P E LR P PPS + PP PR+ +R+R
Sbjct: 537 PAERLRGPLPPSADDNLKTPPLATQEAEAEKPRKPKRQR 575
Score = 32.0 bits (71), Expect = 1.5
Identities = 59/241 (24%), Positives = 81/241 (33%), Gaps = 34/241 (14%)
Query: 170 IPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEE 229
+PP + P +T LPP A + ++ ER + D L E
Sbjct: 461 LPPSADDNLKTPSERQLTPLPPSAPPSADDN----IKTPAERLRGPLPPSADDNLKTPSE 516
Query: 230 EAILLEIPRLPPPAPAEVEGIGEAL-GPEELRLTGWEPGALLMEVTPP-----EELRLPA 283
+ P PP A ++ E L GP P A TPP E P
Sbjct: 517 RQLTPLPPSAPPSADDNIKTPAERLRGP-------LPPSADDNLKTPPLATQEAEAEKPR 569
Query: 284 PPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIR 343
P +R + PPP +RRR D E P++ RA E P P+R
Sbjct: 570 KPKRQRAAEMEPPPEPKRRR---VGDVEPSRKPKR------RRAADVE-PSSPEPKRRRV 619
Query: 344 GPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVP 403
G E R P E + P PK R E + + RR +V + P
Sbjct: 620 GDVEPSRKPKRRRAADVE-------PSSPEPKRRRVGDVEPSRKPKRRRAADVEPSLPEP 672
Query: 404 R 404
+
Sbjct: 673 K 673
>gi|17136078 VGF nerve growth factor inducible precursor [Homo
sapiens]
Length = 615
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/144 (34%), Positives = 64/144 (44%), Gaps = 26/144 (18%)
Query: 159 LEAAIPERVEEIPPEVPTEPREPERIPVTVLP-PEAITILEAEPIRMLEIEGERELPE-V 216
L AA P R E PP + +E +EP + +P P+ + E R E + E EL + V
Sbjct: 20 LGAAPPGRPEAQPPPLSSEHKEP--VAGDAVPGPKDGSAPEVRGARNSEPQDEGELFQGV 77
Query: 217 SRRELDLLIAEEEEAILLEIPRLP--PPAPAEVEGIGEALGPEELRLTGWEPGALLMEVT 274
R L A+LL+ P PPAP+ G GPEE ALL E
Sbjct: 78 DPRAL--------AAVLLQALDRPASPPAPS-----GSQQGPEEEAAE-----ALLTETV 119
Query: 275 PPEELRLPAPPSPERRPPVPPPPR 298
+ LPAP SPE P PP P+
Sbjct: 120 RSQTHSLPAPESPE--PAAPPRPQ 141
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 42.4 bits (98), Expect = 0.001
Identities = 44/162 (27%), Positives = 65/162 (40%), Gaps = 18/162 (11%)
Query: 280 RLPAP---PSPERRPP---VPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECP 333
R P+P PSP RR P +PPPPR RR R + + + S + + P
Sbjct: 313 RRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV--RRRRRSSASLSGSSSSSSSSRSRSP 370
Query: 334 MVQPPERTIRGPAELFR-TPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERR 392
+PP+RT P + R +P+ S PP + A PPPK P+++ + R
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSAS---PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSR 427
Query: 393 KIEVPSEI------EVPREALEPSVPLMVSLEISLEAAEEEK 428
P E E P ++ L +EE+K
Sbjct: 428 VSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDK 469
Score = 35.4 bits (80), Expect = 0.14
Identities = 38/135 (28%), Positives = 49/135 (36%), Gaps = 24/135 (17%)
Query: 275 PPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPM 334
PP R P PP P RR P PPP RR SP ++ +Q R P
Sbjct: 566 PPRRRRTPTPP-PRRRTPSPPPRRR-------------SPSPRRYSPPIQRR----YSPS 607
Query: 335 VQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKI 394
P RT P R + S PP + +H PPPK + + + +
Sbjct: 608 PPPKRRTASPPPPPKRRASPS---PPPKRRV-SH--SPPPKQRSSPVTKRRSPSLSSKHR 661
Query: 395 EVPSEIEVPREALEP 409
+ S REA P
Sbjct: 662 KGSSPSRSTREARSP 676
Score = 32.7 bits (73), Expect = 0.88
Identities = 49/206 (23%), Positives = 77/206 (37%), Gaps = 26/206 (12%)
Query: 274 TPPEELRLPAPPSPERRPPVP-PPPRRR-------RRRRLLFWDKETQISPEKFQEQLQT 325
+PP + R +PP P +R P PPP+RR ++R + + K ++
Sbjct: 607 SPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP 666
Query: 326 RAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEA 385
E QP +R P+ R P S PP G A P+ RR+ P
Sbjct: 667 SRSTREARSPQPNKR--HSPSPRPRAPQTSSSPPPVRRG-----ASSSPQ--RRQSP-SP 716
Query: 386 AAEEERRKIEVPSEIEVPREAL-EPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPE 444
+ RR P ++ + A P VS S+ + E ++ PP +
Sbjct: 717 STRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSP----VQ 772
Query: 445 VEAPE---APALPVVPELPEVPMEMP 467
++P +PA+PV P P
Sbjct: 773 SQSPSTNWSPAVPVKKAKSPTPSPSP 798
Score = 32.0 bits (71), Expect = 1.5
Identities = 13/28 (46%), Positives = 17/28 (60%)
Query: 274 TPPEELRLPAPPSPERRPPVPPPPRRRR 301
+PP + R P P+RR PPPP +RR
Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPPPKRR 624
Score = 30.0 bits (66), Expect = 5.7
Identities = 27/102 (26%), Positives = 36/102 (35%), Gaps = 22/102 (21%)
Query: 274 TPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECP 333
+P + + +P RR P PPP RRRR SP + R
Sbjct: 532 SPRKRQKETSPRGRRRRSPSPPPTRRRR-------------SPSPAPPPRRRRT------ 572
Query: 334 MVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPK 375
PP R P R+P+ + PP + PPPK
Sbjct: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQR---RYSPSPPPK 611
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 42.0 bits (97), Expect = 0.001
Identities = 71/306 (23%), Positives = 102/306 (33%), Gaps = 45/306 (14%)
Query: 207 IEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEP 266
++G L + ++ L+ EE +L+ PPP P G + + TG
Sbjct: 246 MDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG--- 302
Query: 267 GALLMEVTP--PEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQ 324
L+E P P R P SP PP PPPP T P
Sbjct: 303 ---LIENRPQSPATGRTPVFVSP--TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPP 357
Query: 325 TRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEE 384
A + P V PP PA L P + PP + QP P R E
Sbjct: 358 PPATALQAPAVPPP------PAPLQIAPGVLHPAPPPIA---PPLVQPSPPVARAAPVCE 408
Query: 385 AAAEEERRKIEV------PSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEE 438
+ EV P +P + PS P+ V+ A S + P
Sbjct: 409 TVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVT------ALAHPPSGLHPTP--- 459
Query: 439 RWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLS------LEAVHRAVAL-ELQ 491
P P +P P +P P P L ++S LEA+ + + L +++
Sbjct: 460 ----STAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVE 515
Query: 492 ANREPD 497
RE +
Sbjct: 516 EQREQE 521
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 42.0 bits (97), Expect = 0.001
Identities = 71/306 (23%), Positives = 102/306 (33%), Gaps = 45/306 (14%)
Query: 207 IEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEP 266
++G L + ++ L+ EE +L+ PPP P G + + TG
Sbjct: 246 MDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG--- 302
Query: 267 GALLMEVTP--PEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQ 324
L+E P P R P SP PP PPPP T P
Sbjct: 303 ---LIENRPQSPATGRTPVFVSP--TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPP 357
Query: 325 TRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEE 384
A + P V PP PA L P + PP + QP P R E
Sbjct: 358 PPATALQAPAVPPP------PAPLQIAPGVLHPAPPPIA---PPLVQPSPPVARAAPVCE 408
Query: 385 AAAEEERRKIEV------PSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEE 438
+ EV P +P + PS P+ V+ A S + P
Sbjct: 409 TVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVT------ALAHPPSGLHPTP--- 459
Query: 439 RWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLS------LEAVHRAVAL-ELQ 491
P P +P P +P P P L ++S LEA+ + + L +++
Sbjct: 460 ----STAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVE 515
Query: 492 ANREPD 497
RE +
Sbjct: 516 EQREQE 521
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 42.0 bits (97), Expect = 0.001
Identities = 71/306 (23%), Positives = 102/306 (33%), Gaps = 45/306 (14%)
Query: 207 IEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEP 266
++G L + ++ L+ EE +L+ PPP P G + + TG
Sbjct: 246 MDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG--- 302
Query: 267 GALLMEVTP--PEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQ 324
L+E P P R P SP PP PPPP T P
Sbjct: 303 ---LIENRPQSPATGRTPVFVSP--TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPP 357
Query: 325 TRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEE 384
A + P V PP PA L P + PP + QP P R E
Sbjct: 358 PPATALQAPAVPPP------PAPLQIAPGVLHPAPPPIA---PPLVQPSPPVARAAPVCE 408
Query: 385 AAAEEERRKIEV------PSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEE 438
+ EV P +P + PS P+ V+ A S + P
Sbjct: 409 TVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVT------ALAHPPSGLHPTP--- 459
Query: 439 RWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLS------LEAVHRAVAL-ELQ 491
P P +P P +P P P L ++S LEA+ + + L +++
Sbjct: 460 ----STAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVE 515
Query: 492 ANREPD 497
RE +
Sbjct: 516 EQREQE 521
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 42.0 bits (97), Expect = 0.001
Identities = 71/306 (23%), Positives = 102/306 (33%), Gaps = 45/306 (14%)
Query: 207 IEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEP 266
++G L + ++ L+ EE +L+ PPP P G + + TG
Sbjct: 246 MDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG--- 302
Query: 267 GALLMEVTP--PEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQ 324
L+E P P R P SP PP PPPP T P
Sbjct: 303 ---LIENRPQSPATGRTPVFVSP--TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPP 357
Query: 325 TRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEE 384
A + P V PP PA L P + PP + QP P R E
Sbjct: 358 PPATALQAPAVPPP------PAPLQIAPGVLHPAPPPIA---PPLVQPSPPVARAAPVCE 408
Query: 385 AAAEEERRKIEV------PSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEE 438
+ EV P +P + PS P+ V+ A S + P
Sbjct: 409 TVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVT------ALAHPPSGLHPTP--- 459
Query: 439 RWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLS------LEAVHRAVAL-ELQ 491
P P +P P +P P P L ++S LEA+ + + L +++
Sbjct: 460 ----STAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVE 515
Query: 492 ANREPD 497
RE +
Sbjct: 516 EQREQE 521
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/248 (23%), Positives = 87/248 (35%), Gaps = 38/248 (15%)
Query: 236 IPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPP-------EELRLPAPPSPE 288
+P PPP P G A +L+ P PP + + APP+P
Sbjct: 709 VPPPPPPPPPPTPGSAMA----QLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764
Query: 289 RRPPVPPP-PRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAE 347
PP+P P P + + L+ T S + + A P V P ++ PA
Sbjct: 765 PPPPIPAPLPPQAPPKPLVTIPAPT--STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822
Query: 348 LF--RTPTLSGWLPPELL-GLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPR 404
PT +PP L + CA+PPP L P + + ++ S+ P
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS---PVPSVVK------QIASQFPPP- 872
Query: 405 EALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPM 464
P+ P M S + A + + +W + P P+ P P
Sbjct: 873 ----PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS-------PDFPPPPP 921
Query: 465 EMPLVLPP 472
E LV PP
Sbjct: 922 ESSLVFPP 929
Score = 38.1 bits (87), Expect = 0.021
Identities = 43/201 (21%), Positives = 68/201 (33%), Gaps = 50/201 (24%)
Query: 147 PSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEA------ITILEAE 200
P P I Q++H+ + A P P P P+ P + VT+ P + + A
Sbjct: 744 PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803
Query: 201 PIRMLEIEGERE-------------------LPEVSRRELDLLIAEEEEAILLEIPRL-- 239
P + ++ +P + + A+ + L +P +
Sbjct: 804 PTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863
Query: 240 -------PPPAPAEVEG---------IGEALGPEELRLTGWEPGALLMEVT----PPEEL 279
PPP P +E + P W+P ++ + PP E
Sbjct: 864 QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923
Query: 280 RL---PAPPSPERRPPVPPPP 297
L P PPSP PP PPPP
Sbjct: 924 SLVFPPPPPSPVPAPPPPPPP 944
Score = 31.2 bits (69), Expect = 2.6
Identities = 55/266 (20%), Positives = 89/266 (33%), Gaps = 57/266 (21%)
Query: 237 PRLPPPAPAEVEGIGEALGP--------EELRLTGWEPGALLMEVTPPE------ELRLP 282
P PPP P++ + P L+ GAL TPP + ++
Sbjct: 643 PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQIL 702
Query: 283 APPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTI 342
PP+ PP PPPP +P QL+ P P
Sbjct: 703 VPPNGVVPPPPPPPP---------------PPTPGSAMAQLKPAPCAPSLPQFSAPP--- 744
Query: 343 RGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEV 402
P ++ + ++ PP PPP + LP + A + I P+ +
Sbjct: 745 -PPLKIHQVQHITQVAPP---------TPPPPPPIPAPLPPQ-APPKPLVTIPAPTSTKT 793
Query: 403 PREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEV 462
+ + P + + A ++ S IPP +P P +PV P P +
Sbjct: 794 VAPVVTQAAPPTPTPPVP-PAKKQPAFPASYIPP----------SPPTPPVPVPP--PTL 840
Query: 463 PMEMPL-VLPPELELLSLEAVHRAVA 487
P + PP L + +V + +A
Sbjct: 841 PKQQSFCAKPPPSPLSPVPSVVKQIA 866
Score = 29.6 bits (65), Expect = 7.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Query: 272 EVTPPEELRLPAPPSPERRPPVPPPP 297
++ P P+PP P PP PPPP
Sbjct: 614 KIVTPYTASQPSPPLPPPPPPPPPPP 639
Score = 29.6 bits (65), Expect = 7.4
Identities = 11/17 (64%), Positives = 11/17 (64%)
Query: 281 LPAPPSPERRPPVPPPP 297
LP PP P PP PPPP
Sbjct: 628 LPPPPPPPPPPPPPPPP 644
Score = 29.3 bits (64), Expect = 9.7
Identities = 12/23 (52%), Positives = 12/23 (52%)
Query: 275 PPEELRLPAPPSPERRPPVPPPP 297
P L P PP P PP PPPP
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPP 646
Score = 29.3 bits (64), Expect = 9.7
Identities = 12/24 (50%), Positives = 13/24 (54%)
Query: 274 TPPEELRLPAPPSPERRPPVPPPP 297
+PP P PP P PP PPPP
Sbjct: 625 SPPLPPPPPPPPPPPPPPPPPPPP 648
>gi|47078278 choline kinase alpha isoform b [Homo sapiens]
Length = 439
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/70 (37%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 242 PAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRR 301
PAP + A E +L G +P L + PP L LP P P +PP P R
Sbjct: 29 PAPGVGQQRDAASDLESKQLGGQQP-PLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRT 87
Query: 302 RRRLLFWDKE 311
RRR W KE
Sbjct: 88 RRRAYLWCKE 97
>gi|47078276 choline kinase alpha isoform a [Homo sapiens]
Length = 457
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/70 (37%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 242 PAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRR 301
PAP + A E +L G +P L + PP L LP P P +PP P R
Sbjct: 29 PAPGVGQQRDAASDLESKQLGGQQP-PLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRT 87
Query: 302 RRRLLFWDKE 311
RRR W KE
Sbjct: 88 RRRAYLWCKE 97
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 41.2 bits (95), Expect = 0.002
Identities = 80/338 (23%), Positives = 106/338 (31%), Gaps = 31/338 (9%)
Query: 161 AAIPERVEEIPPE--VPTEPREPERIPVTVLPPEAITILEA------EPIRMLEIEGERE 212
AA+P E P VPT P EP V PPE T A EP E
Sbjct: 1005 AAVPTPEEPTSPAAAVPT-PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1063
Query: 213 LPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLME 272
P + A + P P A V E P T EP +
Sbjct: 1064 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAA 1123
Query: 273 VTPPEE-----LRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISP----------E 317
V PEE +P P P P P P + E SP
Sbjct: 1124 VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
Query: 318 KFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQP-PPKA 376
F + T P + E F +P S E L + P P +
Sbjct: 1184 SFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS 1243
Query: 377 LRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPP 436
+P + P E+ P ++ P+ S ++ EE S + +P
Sbjct: 1244 PAAAVPTLEEPTSSAAAVLTPEELSSPAASV-PTPEEPASPAAAVSNLEEPASPAAAVPT 1302
Query: 437 EERWAWP--EVEAPEAPALP--VVPELPEV-PMEMPLV 469
E A P V PE PA+P VP + EV P+ +P +
Sbjct: 1303 PEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFL 1340
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 41.2 bits (95), Expect = 0.002
Identities = 86/363 (23%), Positives = 140/363 (38%), Gaps = 38/363 (10%)
Query: 124 AMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEV---PTEPRE 180
A +++ E A P P SP + + + E PE+ + E P E +
Sbjct: 542 AEVKSPEKAKSPAKEEAKSPPEAKSP-EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600
Query: 181 PERIPVTVL-----PPEAITILEAEPIRMLEIEGERELPEVSRRELD----LLIAEEEEA 231
PE+ V P EA + ++ E E++ + ++ E E+EEA
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA 660
Query: 232 ILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPP---SPE 288
E + P A A+ ++ E + + E PE+ + P SPE
Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720
Query: 289 R-RPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERT-IRGPA 346
+ + PV + + + KE SPEK + + + + P + P + R PA
Sbjct: 721 KAKSPVKEEAKTPEKAKSPV--KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778
Query: 347 ELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREA 406
+ F PE P+ + L E+A A E+ E+P + EV
Sbjct: 779 DKF----------PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK----EIPKKEEVKSPV 824
Query: 407 LEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAP--EAPALPVVPELPEVPM 464
E P V ++ + AEEEK+ + E++ + E EAP EAP P V E E +
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE-EAPKKEAPK-PKVEEKKEPAV 882
Query: 465 EMP 467
E P
Sbjct: 883 EKP 885
Score = 38.5 bits (88), Expect = 0.016
Identities = 90/387 (23%), Positives = 137/387 (35%), Gaps = 44/387 (11%)
Query: 96 LERLHRAQLQIRIDMETELPSLLLPNHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQI 155
LE H+A + + +L + L M L + D M++D +I
Sbjct: 349 LEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALD------IEIAAY 402
Query: 156 RHLLEAA--------IPERVEEIPPEVPT-----EPREPERIPVTVLPPEAITILE--AE 200
R LLE IP + E P++P+ + + E+I V + I+E E
Sbjct: 403 RKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTE 462
Query: 201 PIRMLEIEGERELPEVSRRE-LDLLIAEEEEAILLEIPRLPPPAP--------AEVEGIG 251
++ E E E E E + EEEEA E PPA A+
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKE 522
Query: 252 EALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKE 311
EA P E + E EV PE+ + PA + P P + + E
Sbjct: 523 EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582
Query: 312 TQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQ 371
SP K + + A E P + + PAE P E+ A+
Sbjct: 583 KAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS--PEKAK 639
Query: 372 PPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRI 431
P K + E A E+ + + P + + P +A E P + EA EK++
Sbjct: 640 SPTKEEAKS--PEKAKSPEKEEAKSPEKAKSPVKA-EAKSPEKAKSPVKAEAKSPEKAK- 695
Query: 432 SLIPPEERWAWPEVEAPEAPALPVVPE 458
P +E E ++PE PV E
Sbjct: 696 --SPVKE-----EAKSPEKAKSPVKEE 715
Score = 33.5 bits (75), Expect = 0.51
Identities = 46/199 (23%), Positives = 82/199 (41%), Gaps = 13/199 (6%)
Query: 160 EAAIPERVEEIPPEV----PTEPREPERIPVTVLPPEAITILEAEPIRML----EIEGER 211
E P + EE P EV P + E E+ P T E + E + ++E ++
Sbjct: 819 EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878
Query: 212 ELPEVSRRELDLLIAEEEEAI-LLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEP-GAL 269
E P V + + + A++EEA ++P APA+VE +A E+ + EP A
Sbjct: 879 E-PAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Query: 270 LMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQIS--PEKFQEQLQTRA 327
E + P E + AP + + P + + + + +S P K + + ++
Sbjct: 938 AKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKS 997
Query: 328 HCWECPMVQPPERTIRGPA 346
+ +PPE+ A
Sbjct: 998 SSTDQKDSKPPEKATEDKA 1016
Score = 32.0 bits (71), Expect = 1.5
Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 370 AQPPPKALRRELPEEA-----AAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAA 424
A P K + + EEA A E+ + + P+E++ P +A P+ S +
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568
Query: 425 EEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPE 473
+EE + + E+ P E ++PA PE + P++ P E
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Score = 31.6 bits (70), Expect = 2.0
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 383 EEAAAEEERRKIEVPSEIEVPREALEPSVPLMVS-LEI-SLEAAEEEKSRISLIPPEERW 440
EEAA+ E+ K V E + P EA P S E+ S E A+ + PPE +
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK- 565
Query: 441 AWPEVEAPEAPALPVVPELPEVPMEMPLVLPPE 473
PE E ++PA PE + P + P E
Sbjct: 566 -SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597
>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
sapiens]
Length = 468
Score = 41.2 bits (95), Expect = 0.002
Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 44/179 (24%)
Query: 145 RLPS--PFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITILEAEPI 202
R+PS P+D P A+ + + P+ P E P +P+T PP E EP
Sbjct: 63 RVPSSGPYDCP-------ASFSHPLTRVAPQPPGEDDAPYDVPLTPKPP-----AELEP- 109
Query: 203 RMLEIEGERE-------LPEVSRRE---LDLLIAEEE----------EAILLEIPRLPPP 242
LE EG RE P +R L+L A EE + + ++P L P
Sbjct: 110 -DLEWEGGREPGPPIYAAPSNLKRASALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPE 168
Query: 243 APAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRP----PVPPPP 297
AP E G ++ L L PP RLP+ S RRP PVP P
Sbjct: 169 APPSPEPPGALASHDQDTLA----QLLARSPPPPHRPRLPSAESLSRRPLPALPVPEAP 223
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.138 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,825,770
Number of Sequences: 37866
Number of extensions: 1674546
Number of successful extensions: 16062
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 454
Number of HSP's that attempted gapping in prelim test: 12019
Number of HSP's gapped (non-prelim): 3000
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.