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Search of human proteins with 224586773
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
(777 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 1561 0.0
gi|193290160 CTAGE family, member 4 [Homo sapiens] 1543 0.0
gi|56847634 hypothetical protein LOC441294 [Homo sapiens] 1493 0.0
gi|146262005 CTAGE family, member 6 [Homo sapiens] 1487 0.0
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 1295 0.0
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 1259 0.0
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 1246 0.0
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 1205 0.0
gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isofo... 1137 0.0
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 239 7e-63
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 80 6e-15
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 78 3e-14
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 78 3e-14
gi|55770834 centromere protein F [Homo sapiens] 77 5e-14
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 77 6e-14
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 76 1e-13
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 75 2e-13
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 74 4e-13
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 74 4e-13
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 74 4e-13
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 74 4e-13
gi|118498356 kinectin 1 isoform a [Homo sapiens] 74 5e-13
gi|33620775 kinectin 1 isoform a [Homo sapiens] 74 5e-13
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 74 7e-13
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 73 9e-13
gi|42794779 myosin 18A isoform b [Homo sapiens] 73 1e-12
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 72 2e-12
gi|28416946 myosin 18A isoform a [Homo sapiens] 72 2e-12
gi|156104908 myosin heavy chain 6 [Homo sapiens] 71 4e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 6e-12
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 1561 bits (4043), Expect = 0.0
Identities = 777/777 (100%), Positives = 777/777 (100%)
Query: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW
Sbjct: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE
Sbjct: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
Query: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR
Sbjct: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ
Sbjct: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
Query: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP
Sbjct: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
Query: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE
Sbjct: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF 777
FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF 777
>gi|193290160 CTAGE family, member 4 [Homo sapiens]
Length = 777
Score = 1543 bits (3994), Expect = 0.0
Identities = 769/777 (98%), Positives = 772/777 (99%)
Query: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPGATPQPYLGLVLEEL RVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
AAEEARSLEATCEKL+RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKG+VSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLEL+VNSQ
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
WENGANLDDP KGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EKIS ATE LETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR
Sbjct: 421 EKISRATEGLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
KENAHNKQKLTE ELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
Query: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP
Sbjct: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
Query: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE
Sbjct: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF 777
FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF 777
>gi|56847634 hypothetical protein LOC441294 [Homo sapiens]
Length = 777
Score = 1493 bits (3866), Expect = 0.0
Identities = 746/777 (96%), Positives = 755/777 (97%)
Query: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPGATPQPYLGLVLEEL RVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
AAEEARSLEATCEKL+RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLEL+VNSQ
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
WENGANLDDP KGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EK+S ATE+LETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR
Sbjct: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
KENAHNKQKLTE ELKFELLEKDPNALDVSNTAFGREH+P P+PLG+ SSETRAF SPQ
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
Query: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
TLLEDPL LSPVLP GGGRGP PGNPLDHQITNERGEPS DRL DPHRAPSDTGSLSSP
Sbjct: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
Query: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
VEQD +MMFPPPGQSYPDS LPPQREDRFYSNSERLSG AEPRSFKMTSLDKMD SMPSE
Sbjct: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
MESSRNDAKDDLGNLNVPDSSLPAENEATGPG IPPPLAP+ GPLFPVDTRGPFMRRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF 777
FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPY HPRPGFYPNP F
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF 777
>gi|146262005 CTAGE family, member 6 [Homo sapiens]
Length = 777
Score = 1487 bits (3850), Expect = 0.0
Identities = 742/777 (95%), Positives = 754/777 (97%)
Query: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPGATPQPYLGLVLEEL RVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
AAEEARSLEATCEKL+RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKG+VSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLEL+VNSQ
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
WENGANLDDP KGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
TQQ SLQSENIYFESENQKLQQKLKIMTEFYQE+EMKLYRKLTVEENYRIEEEEKLS+VE
Sbjct: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
Query: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EK+S ATE+LETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR
Sbjct: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
KENAHNKQKLTE ELKFELLEKDPNALDVSNTAFGREH+P P+PLG+ SSETRAF SPQ
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
Query: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
TLLEDPL LSPVLP GGGRGP PGNPLDHQITNERGEPS DRL DPHRAPSDTGSLSSP
Sbjct: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
Query: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
VEQD +MMFPPPGQSYPDS LPPQREDRFYSNSERLSG AEPRSFKMTSLDKMD SMPSE
Sbjct: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
MESSRNDAKDDLGNLNVPDSSLPAENEATGPG IPPPLAP+ GPLFPVDTRGPFMRRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF 777
FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPY HPRPGFYPNP F
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF 777
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 1295 bits (3352), Expect = 0.0
Identities = 651/775 (84%), Positives = 695/775 (89%), Gaps = 2/775 (0%)
Query: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPG TPQPYLGL+LEEL RVVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLW
Sbjct: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGRE+KL LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK
Sbjct: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
Query: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
A E A+SLEATCEKL+RSNSELEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDE
Sbjct: 121 ATE-AQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
SKSLKSQ+AEAK+ K F+M+EER IAIKDALNENSQLQ S KQL Q EAEVWK QVSE
Sbjct: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSE 238
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
LNKQK+TFEDSKVHAEQVLNDKE+HIKTLT L MKD AA+L ED TDDDNLEL++NS+
Sbjct: 239 LNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
Query: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
ENGA LD+PPKGALKKLIHAAKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQ
Sbjct: 299 SENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 358
Query: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
T+QASLQSEN +FE+ENQKLQQKLK+MTE YQENEMKL+RKLTVEENYR+E+EEKLS+V+
Sbjct: 359 TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVD 418
Query: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EKISHATEELETYRK AKDLEEELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLR
Sbjct: 419 EKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLR 478
Query: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
KENAHN+QKLTE ELKFELLEKDP ALDV NTAFGREHSP PSPLG PSSETRAF SP
Sbjct: 479 KENAHNRQKLTETELKFELLEKDPYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPP 538
Query: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
TLLE PLRLSP+LPGGGGRG PGNPLDHQITNERGE S DRL DPHRAPSDTGSLS P
Sbjct: 539 TLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPP 598
Query: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
+QDRRMMFPPPGQSYPDS LPPQR+DRF SNS RLSGPAE RSF M SLDKMD SMPSE
Sbjct: 599 WDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSE 658
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
MESSRND KDDLGNLNVPDSSLPAENEATGPG +PPPLAPI GPLFPVD RGPF+RRGPP
Sbjct: 659 MESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPP 718
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNP 775
FPPPPPG MFGASR YFPP DFPGPP APFAMRN+YPPRG PPYL PRPGF+P P
Sbjct: 719 FPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 773
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 1259 bits (3257), Expect = 0.0
Identities = 633/754 (83%), Positives = 676/754 (89%), Gaps = 2/754 (0%)
Query: 22 VVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGAT 81
VVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLWRSFRSVRSRLYVGRE+KL
Sbjct: 10 VVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALM 69
Query: 82 LSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSE 141
LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK A E A+SLEATCEKL+RSNSE
Sbjct: 70 LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATE-AQSLEATCEKLNRSNSE 128
Query: 142 LEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMS 201
LEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDESKSLKSQ+AEAK+ K F+M+
Sbjct: 129 LEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMN 188
Query: 202 EERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLND 261
EER IAIKDALNENSQLQ S KQL Q EAEVWK QVSELNKQK+TFEDSKVHAEQVLND
Sbjct: 189 EERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLND 247
Query: 262 KENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHA 321
KE+HIKTLT L MKD AA+L ED TDDDNLEL++NS+ ENGA LD+PPKGALKKLIHA
Sbjct: 248 KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHA 307
Query: 322 AKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQ 381
AKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FE+ENQKLQ
Sbjct: 308 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQ 367
Query: 382 QKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLE 441
QKLK+MTE YQENEMKL+RKLTVEENYR+E+EEKLS+V+EKISHATEELETYRK AKDLE
Sbjct: 368 QKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLE 427
Query: 442 EELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLE 501
EELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLRKENAHN+QKLTE ELKFELLE
Sbjct: 428 EELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLE 487
Query: 502 KDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGP 561
KDP ALDV NTAFGREHSP PSPLG PSSETRAF SP TLLE PLRLSP+LPGGGGRG
Sbjct: 488 KDPYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGS 547
Query: 562 SSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRMMFPPPGQSYPDSTL 621
PGNPLDHQITNERGE S DRL DPHRAPSDTGSLS P +QDRRMMFPPPGQSYPDS L
Sbjct: 548 RGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSAL 607
Query: 622 PPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPDSS 681
PPQR+DRF SNS RLSGPAE RSF M SLDKMD SMPSEMESSRND KDDLGNLNVPDSS
Sbjct: 608 PPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSS 667
Query: 682 LPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRD 741
LPAENEATGPG +PPPLAPI GPLFPVD RGPF+RRGPPFPPPPPG MFGASR YFPP D
Sbjct: 668 LPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGD 727
Query: 742 FPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNP 775
FPGPP APFAMRN+YPPRG PPYL PRPGF+P P
Sbjct: 728 FPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 761
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 1246 bits (3225), Expect = 0.0
Identities = 626/746 (83%), Positives = 669/746 (89%), Gaps = 2/746 (0%)
Query: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
MRPD N YGFP ELV+CAAV+GFF VL FLWRSFRSVRSRLYVGRE+KL LSGLIEEK
Sbjct: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
Query: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCL 149
KLLEKFSL+QKEYEGYEVESSL+DASFEK A E A+SLEATCEKL+RSNSELEDEILCL
Sbjct: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATE-AQSLEATCEKLNRSNSELEDEILCL 119
Query: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
EK+LKEEKSKHS+QDELMADISK IQSLEDESKSLKSQ+AEAK+ K F+M+EER IAI
Sbjct: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
Query: 210 KDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
KDALNENSQLQ S KQL Q EAEVWK QVSELNKQK+TFEDSKVHAEQVLNDKE+HIKTL
Sbjct: 180 KDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTL 238
Query: 270 TGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLK 329
T L MKD AA+L ED TDDDNLEL++NS+ ENGA LD+PPKGALKKLIHAAKLN SLK
Sbjct: 239 TERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLK 298
Query: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FE+ENQKLQQKLK+MTE
Sbjct: 299 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTE 358
Query: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVH 449
YQENEMKL+RKLTVEENYR+E+EEKLS+V+EKISHATEELETYRK AKDLEEELERT+H
Sbjct: 359 LYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIH 418
Query: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDV 509
YQ Q+IS+EK+ HDNWLAAR AERNL+DLRKENAHN+QKLTE ELKFELLEKDP ALDV
Sbjct: 419 SYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDV 478
Query: 510 SNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLD 569
NTAFGREHSP PSPLG PSSETRAF SP TLLE PLRLSP+LPGGGGRG PGNPLD
Sbjct: 479 PNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLD 538
Query: 570 HQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRMMFPPPGQSYPDSTLPPQREDRF 629
HQITNERGE S DRL DPHRAPSDTGSLS P +QDRRMMFPPPGQSYPDS LPPQR+DRF
Sbjct: 539 HQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRF 598
Query: 630 YSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
SNS RLSGPAE RSF M SLDKMD SMPSEMESSRND KDDLGNLNVPDSSLPAENEAT
Sbjct: 599 CSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEAT 658
Query: 690 GPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
GPG +PPPLAPI GPLFPVD RGPF+RRGPPFPPPPPG MFGASR YFPP DFPGPP AP
Sbjct: 659 GPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAP 718
Query: 750 FAMRNIYPPRGLPPYLHPRPGFYPNP 775
FAMRN+YPPRG PPYL PRPGF+P P
Sbjct: 719 FAMRNVYPPRGFPPYLPPRPGFFPPP 744
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 1205 bits (3117), Expect = 0.0
Identities = 617/775 (79%), Positives = 660/775 (85%), Gaps = 45/775 (5%)
Query: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPG TPQPYLGL+LEEL RVVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLW
Sbjct: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGRE+KL LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK
Sbjct: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
Query: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
A E A+SLEATCEKL+RSNSELEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDE
Sbjct: 121 ATE-AQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
SKSLKSQ+AEAK+ K F+M+EER IAIKDALNENSQLQ S KQL Q EAEVWK QVSE
Sbjct: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSE 238
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
LNKQK+TFEDSKVHAEQVLNDKE+HIKTLT L MKD AA+L ED TDDDNLEL++NS+
Sbjct: 239 LNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
Query: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
ENGA LD+PPKGALKKLIHAAKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQ
Sbjct: 299 SENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 358
Query: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
T+QASLQSEN +FE+ENQKLQQKLK+MTE YQENEMKL+RKLTVEENYR+E+EEKLS+V+
Sbjct: 359 TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVD 418
Query: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EKISHATEELETYRK AKDLEEELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLR
Sbjct: 419 EKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLR 478
Query: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
KENAHN+QKLTE ELKFELLEKDP ALDV NTAFGR
Sbjct: 479 KENAHNRQKLTETELKFELLEKDPYALDVPNTAFGR------------------------ 514
Query: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
G RG PGNPLDHQITNERGE S DRL DPHRAPSDTGSLS P
Sbjct: 515 ----------------GSRG---PGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPP 555
Query: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
+QDRRMMFPPPGQSYPDS LPPQR+DRF SNS RLSGPAE RSF M SLDKMD SMPSE
Sbjct: 556 WDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSE 615
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
MESSRND KDDLGNLNVPDSSLPAENEATGPG +PPPLAPI GPLFPVD RGPF+RRGPP
Sbjct: 616 MESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPP 675
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNP 775
FPPPPPG MFGASR YFPP DFPGPP APFAMRN+YPPRG PPYL PRPGF+P P
Sbjct: 676 FPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 730
>gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isoform
1 [Homo sapiens]
Length = 745
Score = 1137 bits (2942), Expect = 0.0
Identities = 585/749 (78%), Positives = 636/749 (84%), Gaps = 5/749 (0%)
Query: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
MRPD +PYGFP ELV+ AAV GFF VL FLWRSFRSV SRLYV RE+K LSGLIEEK
Sbjct: 1 MRPDSHPYGFPWELVIRAAVAGFFAVL-FLWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
Query: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCL 149
CKLLEKFSL+QKEYEGYEVESSL++ASFEK A E A+SLEATCEKL+R NSEL EILCL
Sbjct: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATE-AQSLEATCEKLNRFNSELVHEILCL 118
Query: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
EK+LKEEKSKHS+Q+ELMADISK IQSLEDESKSLKSQ+AEAK+ K F+ +EER I I
Sbjct: 119 EKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEI 178
Query: 210 KDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
+DA ENS+LQ S KQL Q EAEVWK QVSEL KQK TFEDSKVHAEQVLNDKENHIKTL
Sbjct: 179 QDAWKENSELQESQKQLLQ-EAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTL 237
Query: 270 TGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLK 329
T L MKD A+LEED TDDDNLEL++NS+ E+GA LD+PPKGALKKLIHAAKLN SLK
Sbjct: 238 TERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLK 297
Query: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+QASLQSEN +FESENQKLQQKLK+MTE
Sbjct: 298 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTE 357
Query: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVH 449
YQENEMKLYRKL VEE R+E+EEKLS+V+E ISHATEELETYRK AKDL+E E+T+H
Sbjct: 358 LYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE-FEKTIH 416
Query: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDV 509
FYQK++I +EK+ HDNW AA TAERNL+DLRKENAHN+QKLTE E K +LLEKDP LDV
Sbjct: 417 FYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDV 476
Query: 510 SNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLD 569
NTAFGR+HSP PSPLG PSSETRA P TLLE PLRLSP+LP GGGRG PGNP D
Sbjct: 477 PNTAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPD 536
Query: 570 HQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRMMFPPPGQSYPDSTLPPQREDRF 629
HQIT ERGE S DRL DPHRAPSD G L+ P EQD RMMFPPPGQSYPDS LPPQR+DRF
Sbjct: 537 HQITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRF 596
Query: 630 YSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
YSN RLSGPAE RSF M SLDKMD SMPSEMESSRND KD+LGNL VPDSSLPAENEAT
Sbjct: 597 YSNCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEAT 656
Query: 690 GPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
GPG +PPPLAPI G LFPVDTRGPF+RRGPPFPPPPPGT+FGAS YF PRD PGPP AP
Sbjct: 657 GPGFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAP 716
Query: 750 FAMRNIYPPRGLPPYLHPRPGFY-PNPTF 777
FAMRN+Y PRG PY PRP F+ P PTF
Sbjct: 717 FAMRNVYLPRGFLPYRPPRPAFFPPAPTF 745
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 239 bits (610), Expect = 7e-63
Identities = 204/758 (26%), Positives = 359/758 (47%), Gaps = 86/758 (11%)
Query: 22 VVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGAT 81
+VA LP+ ++P + YG P + V A +G +FLWR+ V+ R+Y EQ++
Sbjct: 1160 LVATLPDDVQPGPDFYGLPWKPVFITAFLGIASFAIFLWRTVLVVKDRVYQVTEQQISEK 1219
Query: 82 LSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAA-AEEARSLEATCEKLSRSNS 140
L +++E +L++K S +++ + E + +++ + ++EA + + L ++
Sbjct: 1220 LKTIMKENTELVQKLSNYEQKIK--ESKKHVQETRKQNMILSDEAIKYKDKIKTLEKNQE 1277
Query: 141 ELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKM 200
L+D L L+ E+ ++ + +L+++ KSI+ L+D S+ +E +I K+
Sbjct: 1278 ILDDTAKNLRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIALNEAKL 1337
Query: 201 SEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLN 260
SEE+ EN++L+ +QL QQE E W +EL++Q +FE S+ E L
Sbjct: 1338 SEEKVKSECHRVQEENARLKKKKEQL-QQEIEDWSKLHAELSEQIKSFEKSQKDLEVALT 1396
Query: 261 DKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIH 320
K+++I LT + + E + + + + E G + ++ K +K+++
Sbjct: 1397 HKDDNINALTNCITQLNLLECESESEGQNKGGNDSDELANGEVGGDRNEKMKNQIKQMMD 1456
Query: 321 AAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKL 380
++ ++ +E + + ++L TK L + +K L+ + SLQ+ E E + L
Sbjct: 1457 VSRTQTAISVVEEDLKLLQLKLRASVSTKCNLEDQVKKLEDDRNSLQAAKAGLEDECKTL 1516
Query: 381 QQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDL 440
+QK++I+ E YQ+ EM L +KL+ EE R E E +LS +EK A EE++TY++ +++
Sbjct: 1517 RQKVEILNELYQQKEMALQKKLSQEEYERQEREHRLSAADEKAVSAAEEVKTYKRRIEEM 1576
Query: 441 EEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELL 500
E+EL++T ++ Q+ ++EK+ H+NWL AR AER +++ ++E A+ + KL E K +L
Sbjct: 1577 EDELQKTERSFKNQIATHEKKAHENWLKARAAERAIAEEKREAANLRHKLLELTQKMAML 1636
Query: 501 EKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRG 560
+++P + P P G+P+++ +P R P L G G
Sbjct: 1637 QEEPVIV--------------KPMP-GKPNTQ------------NPPRRGP-LSQNGSFG 1668
Query: 561 PSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRMMFPPPGQSYPDST 620
PS GE S ++P P LS+ + +RR M P D
Sbjct: 1669 PSPVSG----------GECSPPLTVEPPVRP-----LSATL--NRRDM-PRSEFGSVDGP 1710
Query: 621 LPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPDS 680
LP R+ + + P++P S T ++ R SS D+ G +N+
Sbjct: 1711 LP---HPRWSAEASGKPSPSDPGSGTATMMNSSSRG------SSPTRVLDE-GKVNMAPK 1760
Query: 681 SLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPR 740
P PG +P P+ GP+ P GP + PF P P PP
Sbjct: 1761 GPPPF-----PG-VPLMSTPMGGPVPPPIRYGPPPQLCGPFGPRP-----------LPPP 1803
Query: 741 DFPGPPHAPFAMRNIYPPRGLPP-----YLHPRPGFYP 773
PG P +R P G+PP LHPR GF P
Sbjct: 1804 FGPG-MRPPLGLREFAP--GVPPGRRDLPLHPR-GFLP 1837
Score = 30.0 bits (66), Expect = 8.6
Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 24/163 (14%)
Query: 314 ALKKLIHAAKLNVSL-KSLEGERNHIIIQLSEVDKTKEELTE----------HIKNLQTQ 362
A++K + + N L K E E + E D E TE H + +Q
Sbjct: 157 AVEKTLQDMEKNPELSKEREPEPEPVEANSEESDSVFSENTEDLQEQFTTQKHHSHANSQ 216
Query: 363 QASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEEN----YRIEEEEKLSR 418
Q E FES + LQ KLK+ + N+ +++ E++ Y++ ++E
Sbjct: 217 ANHAQGEQASFESFEEMLQDKLKVPES--ENNKTSNSSQVSNEQDKIDAYKLLKKEMTLD 274
Query: 419 VEEKISHATEEL----ETYR---KLAKDLEEELERTVHFYQKQ 454
++ K + L ET R L D +EEL+ + K+
Sbjct: 275 LKTKFGSTADALVSDDETTRLVTSLEDDFDEELDTEYYAVGKE 317
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 80.5 bits (197), Expect = 6e-15
Identities = 90/395 (22%), Positives = 176/395 (44%), Gaps = 44/395 (11%)
Query: 74 REQKL---GATLSGLIEEKCKLLEKFSLIQKEYEGYEV--ESSLEDASFEKAAAEEARSL 128
+EQK+ T++ L E + +L ++ +QK + E+ + + + A+ R +
Sbjct: 1110 KEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLM 1169
Query: 129 EATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQI 188
+ +KL+ N+++ED LE+++K +K K E + + S+Q E+++ +K +
Sbjct: 1170 KELNQKLTNKNNKIED----LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLL 1225
Query: 189 AEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHK---QLFQQEAEVWKGQVSELNKQK 245
+ K K +E I LQ S K + QQ+ EV+K Q++E
Sbjct: 1226 VKTKKELADSKQAETDHLI-----------LQASLKGELEASQQQVEVYKIQLAE----- 1269
Query: 246 ITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGA 305
IT E K+H E + E H +TL+ + + + L+E+ + V S++E+
Sbjct: 1270 ITSEKHKIH-EHLKTSAEQHQRTLSAY----QQRVTALQEECRAAKAEQATVTSEFES-- 1322
Query: 306 NLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQAS 365
LK+ + + + + ER H+ + +D+ K +L + NLQ +
Sbjct: 1323 -YKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEML---IDQLKIKLQDSQNNLQINVSE 1378
Query: 366 LQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKL-TVEENYRIEEEEKLSRVEEKIS 424
LQ+ +SE+ L ++ M + E +L KL +++ + + E V + S
Sbjct: 1379 LQT----LQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTS 1434
Query: 425 HATEELETYRKLAKDLEEELERTVHFYQKQVISYE 459
++R + L+EE +TV Q+Q+ E
Sbjct: 1435 QNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKME 1469
Score = 72.0 bits (175), Expect = 2e-12
Identities = 103/416 (24%), Positives = 179/416 (43%), Gaps = 54/416 (12%)
Query: 88 EKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELED--- 144
EK +L + LIQ E S EK +E +L+ E+ EL D
Sbjct: 869 EKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQ-----KELRDRRA 923
Query: 145 EILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKM---S 201
E++ L+ L + S + + ++ + I++LE E K + +I + K++ K S
Sbjct: 924 ELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDS 983
Query: 202 EERRAIAIKDAL----NENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQ 257
+ +K+ L +E QL S + L Q AE +K + E KQ + K A
Sbjct: 984 SRKETQTVKEELESLRSEKDQLSASMRDLIQG-AESYKNLLLEYEKQSEQLDVEKERA-- 1040
Query: 258 VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKK 317
N+ E+ I+ LT L ++ E +D+++L ++ + N L+ ++
Sbjct: 1041 --NNFEHRIEDLTRQL---RNSTLQCETINSDNEDLLARIETLQSNAKLLE------VQI 1089
Query: 318 L-IHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESE 376
L + AK V K LE E+ L + K KE T + L+ Q LQ E + +
Sbjct: 1090 LEVQRAKAMVD-KELEAEK------LQKEQKIKEHATT-VNELEELQVQLQKE----KKQ 1137
Query: 377 NQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKL 436
QK Q+L+++ + Q+ + + ++ E E +KL+ KI E+LE K+
Sbjct: 1138 LQKTMQELELVKKDAQQTTL-MNMEIADYERLMKELNQKLTNKNNKI----EDLEQEIKI 1192
Query: 437 AKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
K +E L+ + Q V YE++ ++ L +KE A +KQ T+
Sbjct: 1193 QKQKQETLQEEITSLQSSVQQYEEKN-------TKIKQLLVKTKKELADSKQAETD 1241
Score = 68.9 bits (167), Expect = 2e-11
Identities = 98/450 (21%), Positives = 191/450 (42%), Gaps = 66/450 (14%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKL 135
Q +G +L+ + EEKC L Q++ + E+E + K EE+ CE+L
Sbjct: 784 QAVGESLAKINEEKCNLA-----FQRDEKVLELEKEI------KCLQEES---VVQCEEL 829
Query: 136 SRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC 195
+ E E + L K+L+E +S+ + ++ + + E+++L Q+ E C
Sbjct: 830 KSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTC 889
Query: 196 KTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHA 255
++ E+ IK+ +EN + K+L + AE+ I +DS +
Sbjct: 890 SKSEIHNEKEKCFIKE--HENLKPLLEQKELRDRRAEL------------ILLKDSLAKS 935
Query: 256 EQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGAL 315
V ND + +K L + ++ + EE + +K + ++ K L
Sbjct: 936 PSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEEL 995
Query: 316 KKL-IHAAKLNVSLKSL----EGERNHII---IQLSEVDKTK----------EELTEHIK 357
+ L +L+ S++ L E +N ++ Q ++D K E+LT ++
Sbjct: 996 ESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLR 1055
Query: 358 NLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLS 417
N Q ++ S+N + + LQ K++ E + K V++ E+ +K
Sbjct: 1056 NSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQR---AKAMVDKELEAEKLQKEQ 1112
Query: 418 RVEEKISHAT--EELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERN 475
+++E HAT ELE + + +++L++T+ Q + K+ A +T N
Sbjct: 1113 KIKE---HATTVNELEELQVQLQKEKKQLQKTM-----QELELVKKD-----AQQTTLMN 1159
Query: 476 --LSDLRKENAHNKQKLTERELKFELLEKD 503
++D + QKLT + K E LE++
Sbjct: 1160 MEIADYERLMKELNQKLTNKNNKIEDLEQE 1189
Score = 59.3 bits (142), Expect = 1e-08
Identities = 87/449 (19%), Positives = 187/449 (41%), Gaps = 70/449 (15%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKL 135
++L ++ L EEK + K +E + + + E E+ E + +E T +
Sbjct: 583 KELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCERE----ERLILELGKKVEQTIQY- 637
Query: 136 SRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC 195
NSELE ++ L L+E + Q D+ + + ++ L ++ + L ++
Sbjct: 638 ---NSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAE-------- 686
Query: 196 KTFKMSEERRAIAIKDALNENSQLQTSHKQ--------LFQQEAEVWKGQVSELNKQKIT 247
+K EN++L + KQ L Q+E + K +++L K+
Sbjct: 687 -------------VKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQL 733
Query: 248 FEDSKVHAEQVL-NDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLEL---------KV 297
+ + + ++L N++ + T +K+ + + ED+ + D + + K+
Sbjct: 734 MVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKI 793
Query: 298 NSQWENGANLDDPPKGALKK---------LIHAAKLNVSLKSLEGERNHIIIQLSEVDKT 348
N + N A D L+K ++ +L L+ E E+ + +L E+
Sbjct: 794 NEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSE 853
Query: 349 KEELTEHIKNLQ--TQQASLQSENIYFESEN-QKLQQKLKIMTE----FYQENEMKLYRK 401
KE L + ++ ++ L+++N+ + E + K +I E F +E+E K
Sbjct: 854 KEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHE---NLK 910
Query: 402 LTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKR 461
+E+ + +L +++ ++ + K+LEE++E +K+ E++
Sbjct: 911 PLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIEN----LEKECKEKEEK 966
Query: 462 GHDNWLAARTAERNLSDLRKENAHNKQKL 490
+ L A A++ L RKE K++L
Sbjct: 967 INKIKLVAVKAKKELDSSRKETQTVKEEL 995
Score = 55.1 bits (131), Expect = 2e-07
Identities = 94/471 (19%), Positives = 197/471 (41%), Gaps = 51/471 (10%)
Query: 91 KLLEKFSLIQKEYEGY--EVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEILC 148
+LL+ ++ Q+E + ++E+S ++ E E + E ++ S ++ + C
Sbjct: 240 ELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELK--ENLVKQCEASEKNIQKKYEC 297
Query: 149 LEKDLKEEKSKHSQQDELMAD-----------ISKSIQSLEDESKSLKSQ---IAEAKII 194
++L++ S +Q +++ + +++ ++ LED K L+SQ + +
Sbjct: 298 ELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTY 357
Query: 195 CKTFKMSEERRAIAIKDAL---NENSQLQTSHKQLFQQEA----EVWKGQVSELNKQKIT 247
K+ E A IKD E+ + + + L ++E E K +++ LNKQ
Sbjct: 358 MNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCY 417
Query: 248 FEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANL 307
+ H +V + KE H K ++ + L + + L ++ E NL
Sbjct: 418 TVEQ--HNREVQSLKEQHQKEIS------ELNETFLSDSEKEKLTLMFEIQGLKEQCENL 469
Query: 308 DDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKE-----ELTEHIKNLQTQ 362
+ A+ ++ L++ GE I Q E K ++ EL + ++ T+
Sbjct: 470 QQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTE 529
Query: 363 QASLQSENIYFESENQKLQQKLKIMTEFYQENEMK-LYRKLTVEENYRIEEEEKLSRVEE 421
+ +L + EN+KL + +++ E EN +K L K V + + L +E
Sbjct: 530 KDALLETVNRLQGENEKLLSQQELVPEL--ENTIKNLQEKNGVYLLSLSQRDTMLKELEG 587
Query: 422 KISHATEELETYRKLAKDLEEELE---RTVHFYQKQVISYEKRGHDNWLAARTAERNLSD 478
KI+ TEE + + K+ EE++ + ++ ++ K+ E+ +++
Sbjct: 588 KINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNE 647
Query: 479 LR-------KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCS 522
L KE N QKL + ++ ++L +D L + E++ S
Sbjct: 648 LTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLS 698
Score = 42.7 bits (99), Expect = 0.001
Identities = 59/300 (19%), Positives = 128/300 (42%), Gaps = 24/300 (8%)
Query: 149 LEKDLKEEKSKHSQQDELMADISKS-IQSLEDESKSLKSQIAEAKIICKTFKMSEERRAI 207
LE KE+ K +++ ++ +KS LE E + L+S+ ++E A+
Sbjct: 22 LETLPKEDLIKFAKKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTGDIIKALTERLDAL 81
Query: 208 AIKDALNENSQLQTSHKQL-FQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHI 266
++ A E L + + +QE E ++ + +K+ E S ++ + + + +N +
Sbjct: 82 LLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKE---LEQSHINYVKEIENLKNEL 138
Query: 267 KTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNV 326
+ + A L++ + N +L+++ Q + N +D K KL
Sbjct: 139 MAVRSKY---SEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVK----------KLQE 185
Query: 327 SLKSLE-GERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLK 385
++ + G I+ ++D T +E E + LQ +++ + +++ LQ++L
Sbjct: 186 EIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQN---IIEANSQHYQKNINSLQEELL 242
Query: 386 IMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELE 445
+ +QE +L ++ E KL+ ++E + E E + + K E ELE
Sbjct: 243 QLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASE--KNIQKKYECELE 300
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 78.2 bits (191), Expect = 3e-14
Identities = 94/410 (22%), Positives = 175/410 (42%), Gaps = 34/410 (8%)
Query: 124 EARSLEATCEKLSRSNSELE---DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
E +SL T E+L + +E +IL +EK+ + K + + +S+Q+ ++
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 527
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
SK L + A+ + +T + + ER+ ++ +Q +S +Q Q AE + +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 241 LNK-------------QKITFEDSKVHAE-QVLNDKENHIKTLTGHLPMMKDQAAVLEED 286
NK KI FE ++ E + +K + L L ++ + +L++
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Query: 287 TTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVD 346
T+ K+ + + + L+ + K L L L+SLE E + QL E +
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS----QLDEEN 703
Query: 347 KTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEM--KLYRKLTV 404
E +K + A LQ EN ESE ++L++ L+++ +++ E Y+ L +
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763
Query: 405 EENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHD 464
EN R+ ++ L +KI EL+ + L++ LE + K++ EK
Sbjct: 764 -ENQRL--QKTLENSNKKIQQLESELQDLEMENQTLQKNLEE-LKISSKRLEQLEKENKS 819
Query: 465 NWLAARTAERNLSDLRKENAHNKQK-------LTERELKFELLEKDPNAL 507
E++ L KEN +Q+ L E +K LEK+ L
Sbjct: 820 LEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL 869
Score = 75.9 bits (185), Expect = 1e-13
Identities = 99/441 (22%), Positives = 187/441 (42%), Gaps = 31/441 (7%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSL-IQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEK 134
+K TL E + K+LE+ + + + S + + K +E + L + ++
Sbjct: 539 EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 135 LSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKII 194
S S++E E ++K+L+ K K + +EL + LE E++ L+ +I KI
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEEL----ENELHHLEKENELLQKKITNLKIT 654
Query: 195 CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEA-EVWKGQVSELNKQKITFEDSKV 253
C+ + E+ + ++ L + FQ E+ E Q+ E N + +S
Sbjct: 655 CEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Query: 254 HAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKG 313
A + + K L +K +L+ + LE+ L +
Sbjct: 715 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLEN 774
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEV---DKTKEELTEHIKNLQTQQASLQSEN 370
+ KK+ +L L+ LE E + L E+ K E+L + K+L+ + + L+ +
Sbjct: 775 SNKKI---QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 371 IYFESENQKLQQKLKIMTEFYQENEMK----------LYRKLTV--EENYRIEEEEKLSR 418
E EN++L+Q+ +I +EN +K L +++ + E R++E EK ++
Sbjct: 832 KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Query: 419 VEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSD 478
E + AT +++T L +DL E +T Q+ EK H+ ER L D
Sbjct: 892 --ELVKRATIDIKTLVTLREDLVSEKLKT----QQMNNDLEKLTHELEKIGLNKERLLHD 945
Query: 479 LRKENAHNKQKLTERELKFEL 499
+ ++ KL E +L+ L
Sbjct: 946 -EQSTDDSRYKLLESKLESTL 965
Score = 75.9 bits (185), Expect = 1e-13
Identities = 110/483 (22%), Positives = 192/483 (39%), Gaps = 69/483 (14%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA----EEARSLE 129
+ ++L + GL E +L + K+ + ++ES L+D E EE +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTLQKNLEELKISS 807
Query: 130 ATCEKLSRSNSELEDEILCLEKDLK--EEKSKHSQQ-----DELMADISKSIQSLEDESK 182
E+L + N LE E LEKD K E+++K +Q D + + + I +LE E+K
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Query: 183 SLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELN 242
+L +I K C K E+ +K A + L T + L +E K Q +
Sbjct: 868 TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLV---SEKLKTQQMNND 924
Query: 243 KQKITFEDSKV--------HAEQVLNDKENHI------KTLTGHLPMMKDQAAVLEEDTT 288
+K+T E K+ H EQ +D + TL L + +++ A LE
Sbjct: 925 LEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLE 984
Query: 289 DDDNLE----------------LKVNSQWENGANLDDPPKGALKKLIHAAK------LNV 326
+ N LK E P G K ++ L V
Sbjct: 985 ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKV 1044
Query: 327 SLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQK--- 383
+ +E ERN+ +Q K+ L +K L+TQ +LQ++ + + + LQ++
Sbjct: 1045 KDRLIEVERNNATLQAE-----KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTT 1099
Query: 384 LKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEE 443
L+ Q L + T N + + S +E + +E E + L L ++
Sbjct: 1100 LQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKD 1159
Query: 444 LERTVHFYQKQVISYE----KRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFEL 499
E+ +++Q YE K G ++A +NL ++ +L +++ + E
Sbjct: 1160 HEKLELLHERQASEYESLISKHG-----TLKSAHKNLEVEHRDLEDRYNQLLKQKGQLED 1214
Query: 500 LEK 502
LEK
Sbjct: 1215 LEK 1217
Score = 60.8 bits (146), Expect = 5e-09
Identities = 95/441 (21%), Positives = 188/441 (42%), Gaps = 65/441 (14%)
Query: 134 KLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
K + S L E+ + ++ + + ++ E + D + ++ +E E K L+ +
Sbjct: 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS 300
Query: 194 ICKTFKM-SEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSK 252
++ +M +E A+ K + + + S + + E +K +V EL + ++K
Sbjct: 301 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK 360
Query: 253 VHAEQVLN------------DKEN-HIKTLTGHLPMMKDQ-AAVLEEDTTDDDNLELKVN 298
E L +KEN +K + M +D +EE ++ LE+
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK 420
Query: 299 SQWENGANLDDPPKGALKKLIHAAKLNVS-LKSLEGERNHIII-QLSEVDKTKEELTEHI 356
+ +L L+++ ++L+ + KSL E N + +L +++ + LT+ +
Sbjct: 421 QSMDESLHLG----WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTV 476
Query: 357 KNLQTQQASLQ---SENIYFESENQKLQQKLKIM-TEFYQE-----NEMKLYRKLTVE-- 405
+ L+T S++ S+ + E ENQ+L +K++I+ E QE N L + L E
Sbjct: 477 EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA 536
Query: 406 ------ENYRIEEEEKLSRVEEKISHATEELETYRKLA--------KDLEEELERTVHFY 451
E R E ++ +E++ H + + + R+ + KD+E+E + +H
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE-NKILHES 595
Query: 452 QKQV------ISYEKRGHDNWL--------AARTAERNLSDLRKENAHNKQKLTERELKF 497
K+ I +EKR L A E L L KEN ++K+T ++
Sbjct: 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITC 655
Query: 498 ELLEKDPNALDVSNTAFGREH 518
E +E AL+ N+ RE+
Sbjct: 656 EKIE----ALEQENSELEREN 672
Score = 54.7 bits (130), Expect = 3e-07
Identities = 95/465 (20%), Positives = 191/465 (41%), Gaps = 69/465 (14%)
Query: 74 REQKLGATLSGLIEEKC----KLLEKFSLIQKEYEGYE--------VESSL----EDASF 117
+E+K+ A L +EE +L ++ ++K YE + V+SS ED +
Sbjct: 972 KEEKIAA-LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKW 1030
Query: 118 EKAAAEEARSLEATCEKL---SRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSI 174
E+ + E R L ++L R+N+ L+ E L+ LK+ +++++ + + +
Sbjct: 1031 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1090
Query: 175 QSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV- 233
SL++++ +L++Q A+ ++ T L + S L+ ++ + ++ ++
Sbjct: 1091 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLK 1150
Query: 234 --WKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD 291
+ + + K ++ E E +++ G L V D D
Sbjct: 1151 SLYDSLIKDHEKLELLHERQASEYESLISKH--------GTLKSAHKNLEVEHRDLEDRY 1202
Query: 292 NLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSL----KSLEGERNHIIIQLSEVDK 347
N LK Q E+ L+ K +K++ K + ++ K L GE + + S++ K
Sbjct: 1203 NQLLKQKGQLED---LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK 1259
Query: 348 TKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIM--TEFYQENEMKLYRKL--- 402
E L KNL++ + + E E+E KL+++ + + T N+ +L +L
Sbjct: 1260 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1319
Query: 403 TVEENYRI------------------EEEEKLSRVEEKISHATEELETYRKLAKDLEEEL 444
EEN + E + L VE++ ++L R+ + LEE++
Sbjct: 1320 LEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR--QYIDKLNELRRQKEKLEEKI 1377
Query: 445 ERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQK 489
FY R NW+ + R L +K+ +QK
Sbjct: 1378 MDQYKFYDPS----PPRRRGNWITLKM--RKLIKSKKDINRERQK 1416
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 78.2 bits (191), Expect = 3e-14
Identities = 94/410 (22%), Positives = 175/410 (42%), Gaps = 34/410 (8%)
Query: 124 EARSLEATCEKLSRSNSELE---DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
E +SL T E+L + +E +IL +EK+ + K + + +S+Q+ ++
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 527
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
SK L + A+ + +T + + ER+ ++ +Q +S +Q Q AE + +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587
Query: 241 LNK-------------QKITFEDSKVHAE-QVLNDKENHIKTLTGHLPMMKDQAAVLEED 286
NK KI FE ++ E + +K + L L ++ + +L++
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Query: 287 TTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVD 346
T+ K+ + + + L+ + K L L L+SLE E + QL E +
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS----QLDEEN 703
Query: 347 KTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEM--KLYRKLTV 404
E +K + A LQ EN ESE ++L++ L+++ +++ E Y+ L +
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763
Query: 405 EENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHD 464
EN R+ ++ L +KI EL+ + L++ LE + K++ EK
Sbjct: 764 -ENQRL--QKTLENSNKKIQQLESELQDLEMENQTLQKNLEE-LKISSKRLEQLEKENKS 819
Query: 465 NWLAARTAERNLSDLRKENAHNKQK-------LTERELKFELLEKDPNAL 507
E++ L KEN +Q+ L E +K LEK+ L
Sbjct: 820 LEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL 869
Score = 77.4 bits (189), Expect = 5e-14
Identities = 99/441 (22%), Positives = 189/441 (42%), Gaps = 32/441 (7%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSL-IQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEK 134
+K TL E + K+LE+ + + + S + + K +E + L + ++
Sbjct: 539 EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 135 LSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKII 194
S S++E E ++K+L+ K K + +EL + LE E++ L+ +I KI
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEEL----ENELHHLEKENELLQKKITNLKIT 654
Query: 195 CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEA-EVWKGQVSELNKQKITFEDSKV 253
C+ + E+ + ++ L + FQ E+ E Q+ E N + +S
Sbjct: 655 CEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Query: 254 HAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKG 313
A + + K L +K +L+ + LE+ L +
Sbjct: 715 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLEN 774
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEV---DKTKEELTEHIKNLQTQQASLQSEN 370
+ KK+ +L L+ LE E + L E+ K E+L + K+L+ + + L+ +
Sbjct: 775 SNKKI---QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 371 IYFESENQKLQQKLKIMTEFYQENEMK----------LYRKLTV--EENYRIEEEEKLSR 418
E EN++L+Q+ +I +EN +K L +++ + E R++E EK ++
Sbjct: 832 KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Query: 419 VEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSD 478
E + AT +++T L +DL E +T Q+ EK H+ ER L D
Sbjct: 892 --ELVKRATIDIKTLVTLREDLVSEKLKT----QQMNNDLEKLTHELEKIGLNKERLLHD 945
Query: 479 LRKENAHNKQKLTERELKFEL 499
+++ ++ KL E +L+ L
Sbjct: 946 --EQSTDDRYKLLESKLESTL 964
Score = 76.6 bits (187), Expect = 8e-14
Identities = 110/482 (22%), Positives = 194/482 (40%), Gaps = 68/482 (14%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA----EEARSLE 129
+ ++L + GL E +L + K+ + ++ES L+D E EE +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTLQKNLEELKISS 807
Query: 130 ATCEKLSRSNSELEDEILCLEKDLK--EEKSKHSQQ-----DELMADISKSIQSLEDESK 182
E+L + N LE E LEKD K E+++K +Q D + + + I +LE E+K
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Query: 183 SLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELN 242
+L +I K C K E+ +K A + L T + L +E K Q +
Sbjct: 868 TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLV---SEKLKTQQMNND 924
Query: 243 KQKITFEDSKV--------HAEQVLNDKENHIK-----TLTGHLPMMKDQAAVLEEDTTD 289
+K+T E K+ H EQ +D+ ++ TL L + +++ A LE +
Sbjct: 925 LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEE 984
Query: 290 DDNLE----------------LKVNSQWENGANLDDPPKGALKKLIHAAK------LNVS 327
N LK E P G K ++ L V
Sbjct: 985 STNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVK 1044
Query: 328 LKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQK---L 384
+ +E ERN+ +Q K+ L +K L+TQ +LQ++ + + + LQ++ L
Sbjct: 1045 DRLIEVERNNATLQAE-----KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTL 1099
Query: 385 KIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEEL 444
+ Q L + T N + + S +E + +E E + L L ++
Sbjct: 1100 QTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDH 1159
Query: 445 ERTVHFYQKQVISYE----KRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELL 500
E+ +++Q YE K G ++A +NL ++ +L +++ + E L
Sbjct: 1160 EKLELLHERQASEYESLISKHG-----TLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDL 1214
Query: 501 EK 502
EK
Sbjct: 1215 EK 1216
Score = 60.8 bits (146), Expect = 5e-09
Identities = 95/441 (21%), Positives = 188/441 (42%), Gaps = 65/441 (14%)
Query: 134 KLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
K + S L E+ + ++ + + ++ E + D + ++ +E E K L+ +
Sbjct: 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS 300
Query: 194 ICKTFKM-SEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSK 252
++ +M +E A+ K + + + S + + E +K +V EL + ++K
Sbjct: 301 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK 360
Query: 253 VHAEQVLN------------DKEN-HIKTLTGHLPMMKDQ-AAVLEEDTTDDDNLELKVN 298
E L +KEN +K + M +D +EE ++ LE+
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK 420
Query: 299 SQWENGANLDDPPKGALKKLIHAAKLNVS-LKSLEGERNHIII-QLSEVDKTKEELTEHI 356
+ +L L+++ ++L+ + KSL E N + +L +++ + LT+ +
Sbjct: 421 QSMDESLHLG----WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTV 476
Query: 357 KNLQTQQASLQ---SENIYFESENQKLQQKLKIM-TEFYQE-----NEMKLYRKLTVE-- 405
+ L+T S++ S+ + E ENQ+L +K++I+ E QE N L + L E
Sbjct: 477 EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA 536
Query: 406 ------ENYRIEEEEKLSRVEEKISHATEELETYRKLA--------KDLEEELERTVHFY 451
E R E ++ +E++ H + + + R+ + KD+E+E + +H
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE-NKILHES 595
Query: 452 QKQV------ISYEKRGHDNWL--------AARTAERNLSDLRKENAHNKQKLTERELKF 497
K+ I +EKR L A E L L KEN ++K+T ++
Sbjct: 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITC 655
Query: 498 ELLEKDPNALDVSNTAFGREH 518
E +E AL+ N+ RE+
Sbjct: 656 EKIE----ALEQENSELEREN 672
Score = 54.7 bits (130), Expect = 3e-07
Identities = 95/465 (20%), Positives = 191/465 (41%), Gaps = 69/465 (14%)
Query: 74 REQKLGATLSGLIEEKC----KLLEKFSLIQKEYEGYE--------VESSL----EDASF 117
+E+K+ A L +EE +L ++ ++K YE + V+SS ED +
Sbjct: 971 KEEKIAA-LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKW 1029
Query: 118 EKAAAEEARSLEATCEKL---SRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSI 174
E+ + E R L ++L R+N+ L+ E L+ LK+ +++++ + + +
Sbjct: 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1089
Query: 175 QSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV- 233
SL++++ +L++Q A+ ++ T L + S L+ ++ + ++ ++
Sbjct: 1090 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLK 1149
Query: 234 --WKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD 291
+ + + K ++ E E +++ G L V D D
Sbjct: 1150 SLYDSLIKDHEKLELLHERQASEYESLISKH--------GTLKSAHKNLEVEHRDLEDRY 1201
Query: 292 NLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSL----KSLEGERNHIIIQLSEVDK 347
N LK Q E+ L+ K +K++ K + ++ K L GE + + S++ K
Sbjct: 1202 NQLLKQKGQLED---LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK 1258
Query: 348 TKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIM--TEFYQENEMKLYRKL--- 402
E L KNL++ + + E E+E KL+++ + + T N+ +L +L
Sbjct: 1259 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1318
Query: 403 TVEENYRI------------------EEEEKLSRVEEKISHATEELETYRKLAKDLEEEL 444
EEN + E + L VE++ ++L R+ + LEE++
Sbjct: 1319 LEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR--QYIDKLNELRRQKEKLEEKI 1376
Query: 445 ERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQK 489
FY R NW+ + R L +K+ +QK
Sbjct: 1377 MDQYKFYDPS----PPRRRGNWITLKM--RKLIKSKKDINRERQK 1415
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 77.4 bits (189), Expect = 5e-14
Identities = 105/456 (23%), Positives = 197/456 (43%), Gaps = 50/456 (10%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEK--------AAAEEARSLEATCEKLS 136
L++E L + S + +YE V +LE A EK + EE L EKL
Sbjct: 2068 LVKESESLQARLS--ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLR 2125
Query: 137 RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICK 196
E + L + + LKE + ++ + + ++ + +Q E+ + + +K +
Sbjct: 2126 VRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVE 2185
Query: 197 TFKMSEERRAIAIK----DALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFE--- 249
T K E A ++K D + S+ + KQ+ +++ GQ+SEL+K +F+
Sbjct: 2186 TLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQ-----GQLSELDKLLSSFKSLL 2240
Query: 250 DSKVHAE-QVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLD 308
+ K AE Q+ + + ++ L L + + A L D +K Q +LD
Sbjct: 2241 EEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL-----CGDQEIMKATEQ-----SLD 2290
Query: 309 DPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQ--ASL 366
P + + KL L++ E ++ ++ QL E + + L ++NL+ + A
Sbjct: 2291 PPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIART 2350
Query: 367 QSENIYFESENQK-----LQQKLKIMTEFYQENEMKLYRKLTVEENYRIE---EEEKLSR 418
E+ E+EN K L+ K++ MT+ + E+ + + +EN E E+E++S
Sbjct: 2351 NQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISE 2410
Query: 419 VEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRG---HDNWLAARTAERN 475
+E S L+ + ++E+ + Q Q+ +R H++ A + E+N
Sbjct: 2411 LEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQN 2470
Query: 476 LSD----LRKENAHNKQKLTERELKFELLEKDPNAL 507
LS L E A Q L E + + +L+ N L
Sbjct: 2471 LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGL 2506
Score = 69.3 bits (168), Expect = 1e-11
Identities = 107/466 (22%), Positives = 206/466 (44%), Gaps = 68/466 (14%)
Query: 86 IEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDE 145
++EK +LL+ S +V L+D + + E+ +SLE + LS + ELE++
Sbjct: 2009 VKEKTELLQTLSS--------DVSELLKDKTHLQ---EKLQSLEKDSQALSLTKCELENQ 2057
Query: 146 ILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEE-- 203
I L K+ KE K S + L A +S+S + SK+L++ + E ++E
Sbjct: 2058 IAQLNKE-KELLVKES--ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEV 2114
Query: 204 ---RRAI---AIKDALNENSQLQTSHK-QLFQQEAEVWKGQVSELNKQKITFEDSKVHAE 256
RR I ++ +E QL + K + ++E + K +V L ++ + S+ + E
Sbjct: 2115 HQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERE---LQMSEENQE 2171
Query: 257 QVLNDKEN---HIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKG 313
V+ D EN ++TL + M V E D + + S+ EN +G
Sbjct: 2172 LVILDAENSKAEVETLKTQIEEMARSLKVFELDL-------VTLRSEKENLTKQIQEKQG 2224
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEH-IKNLQTQQASLQSENIY 372
L +L KL S KSL E+ IQ+ E KT E+ ++ +K L A+L +
Sbjct: 2225 QLSEL---DKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEI 2281
Query: 373 FESENQKLQ-------------QKLKIMTEFYQENEMKLYRKLTVEENY---------RI 410
++ Q L +KL+ E ++ ++ + ++L E++ +
Sbjct: 2282 MKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENL 2341
Query: 411 EEEEKLSRVEEKISHATEELETYRKLAKDLEEELE---RTVHFYQKQVISYEKRGHDNWL 467
E E +++R ++ HA E E + + L+ ++E +++ + V++ +
Sbjct: 2342 ERELEIARTNQE--HAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTN 2399
Query: 468 AARTAERNLSDLRKENAHNKQKLTEREL-KFELLEKDPNALDVSNT 512
+ + +S+L N+ + L E+E K ++ EK A+++ T
Sbjct: 2400 ELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQT 2445
Score = 57.8 bits (138), Expect = 4e-08
Identities = 104/439 (23%), Positives = 192/439 (43%), Gaps = 60/439 (13%)
Query: 72 VGREQKLGATLSGLIE-------EKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEE 124
VG +K + LS +E E + +E + + E + +SS ED A +
Sbjct: 1832 VGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVND 1891
Query: 125 A---RSLEATCEKLSRSNSE---LEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLE 178
+ R L+ E LSR SE +E E L LE DL+ +++ ++ + K I LE
Sbjct: 1892 SWKERFLDVENE-LSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLE 1950
Query: 179 DESKSLKSQIAEAKIICKTFKMSEERRAI-AIKDALNENSQLQTSHKQ-----LFQQEAE 232
+E + S+ + + T MS++ A+ + + + E +Q SH+ + EAE
Sbjct: 1951 EELSVVTSERNQLRGELDT--MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAE 2008
Query: 233 V---------WKGQVSELNKQKITFEDSKVHAE---QVLN----DKENHIKTLTGHLPMM 276
V VSEL K K ++ E Q L+ + EN I L ++
Sbjct: 2009 VKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELL 2068
Query: 277 KDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALK-----KLIH-----AAKLNV 326
++ L+ ++ D +L V+ E A L + + AL+ + +H KL V
Sbjct: 2069 VKESESLQARLSESDYEKLNVSKALE--AALVEKGEFALRLSSTQEEVHQLRRGIEKLRV 2126
Query: 327 SLKSLEGERNHIIIQLSEVDKTKEELTEHIKNL--QTQQASLQSENIYFESENQK----- 379
+++ E ++ HI +L E ++ + L + ++NL + Q + E + ++EN K
Sbjct: 2127 RIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVET 2186
Query: 380 LQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEK---LSRVEEKISHATEELETYRKL 436
L+ +++ M + E+ L + +EN + +EK LS +++ +S LE +
Sbjct: 2187 LKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQA 2246
Query: 437 AKDLEEELERTVHFYQKQV 455
++EE + V Q Q+
Sbjct: 2247 EIQIKEESKTAVEMLQNQL 2265
Score = 57.8 bits (138), Expect = 4e-08
Identities = 105/531 (19%), Positives = 217/531 (40%), Gaps = 105/531 (19%)
Query: 59 LWRSFRSVRSRLYVGREQKL--GATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDAS 116
L R +R R+ +++L L E L +K +++E + E L
Sbjct: 2117 LRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILD 2176
Query: 117 FEKAAAEEARSLEATCEKLSRSNSELEDEILCLE-------KDLKEEKSKHSQQDELMAD 169
E + AE +L+ E+++RS E +++ L K ++E++ + S+ D+L++
Sbjct: 2177 AENSKAE-VETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSS 2235
Query: 170 ISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIA---------------IKDALN 214
++ E +K + A + + ++ E A+A + +
Sbjct: 2236 FKSLLEEKEQAEIQIKEESKTAVEMLQN-QLKELNEAVAALCGDQEIMKATEQSLDPPIE 2294
Query: 215 ENSQLQTSHKQL--------------------FQQEAEVWKGQVSELNKQKITFEDSKVH 254
E QL+ S ++L + A++ KG+V L ++ ++ H
Sbjct: 2295 EEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEH 2354
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDT----TDDDNL------------ELKV- 297
A + + ++TL + M LE D ++ +NL EL++
Sbjct: 2355 AALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEII 2414
Query: 298 NSQWENGANLDDPPKGALKKLIHAAK--LNVSLKSLEGERNHIIIQLSEVDKTKEE-LTE 354
NS +EN + K +K+ A L LK L ER + E K KE+ L+
Sbjct: 2415 NSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELN-ERVAALHNDQEACKAKEQNLSS 2473
Query: 355 HIKNLQTQQASL-----QSENIYF-------------ESENQKLQQK------------- 383
++ L+ ++A L +++N Y E QKL++K
Sbjct: 2474 QVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQD 2533
Query: 384 -LKIMTEFYQ-ENEMKLYRKLTVE-ENYRIEEEEKLSRVEEKISHATEELETYRKLAKDL 440
+++++ Q E E +L+++ +E N +E E+K+ ++ K + + LE + K+L
Sbjct: 2534 QEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNL 2593
Query: 441 EEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLT 491
E ELE T + +S+ ++ + +R + ++ ++ A +++L+
Sbjct: 2594 ENELELT----KMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELS 2640
Score = 56.6 bits (135), Expect = 9e-08
Identities = 91/433 (21%), Positives = 188/433 (43%), Gaps = 54/433 (12%)
Query: 85 LIEEKCKLLEKFSLIQK-EYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELE 143
L + K +L+EK ++ K E + + AS + A E+ L+ E LS E
Sbjct: 322 LEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ--KLKKLTEDLSCQRQNAE 379
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFK---M 200
LE+ +KE++ + Q+EL +S Q+L+ E +K+++ + K
Sbjct: 380 SARCSLEQKIKEKEKEF--QEELSRQ-QRSFQTLDQECIQMKARLTQELQQAKNMHNVLQ 436
Query: 201 SEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKV------- 253
+E + ++K L N L+ ++L + E Q+ E N+ + + E+ K
Sbjct: 437 AELDKLTSVKQQLENN--LEEFKQKLCRAEQAFQASQIKE-NELRRSMEEMKKENNLLKS 493
Query: 254 HAEQVLNDK---ENHIKTLTGHLPMMKDQAAVLEEDTTDDD----NLELKVNSQWENGAN 306
H+EQ + E +K + L ++ A ++ T + +L+ K+N Q EN
Sbjct: 494 HSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQ-ENSLT 552
Query: 307 LDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASL 366
L+ KL +++ LE +R+ L + + E+L + + + + +L
Sbjct: 553 LE--------------KLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Query: 367 QSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHA 426
S + E ++L+++ + + + ENE L + + +EN ++ KI+H
Sbjct: 599 LSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKEN-----------LQSKINHL 647
Query: 427 TEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHN 486
L+T + + + E + RT+ ++ +S E R N L +++ E L
Sbjct: 648 ETCLKTQQIKSHEYNERV-RTLEM-DRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQ 705
Query: 487 KQKLTERELKFEL 499
K + ++++ + E+
Sbjct: 706 KAEFSDQKHQKEI 718
Score = 48.5 bits (114), Expect = 2e-05
Identities = 84/381 (22%), Positives = 159/381 (41%), Gaps = 49/381 (12%)
Query: 107 EVESSLEDASFE-KAAAEEARSLEATCEKLSRSNSELED---EILCLEKDLKEEKSKHSQ 162
E S+LE+ E + ++ + +A ++L +SN LED E+ L + L EK + S
Sbjct: 901 ETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMS- 959
Query: 163 QDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTS 222
+++ + I+ L E+ +LK I +LN+
Sbjct: 960 --SIISLNKREIEELTQENGTLKE----------------------INASLNQEKMNLIQ 995
Query: 223 HKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAV 282
+ F + + +SEL+ Q ++ K+ Q + N + L+ K +AA
Sbjct: 996 KSESFANYIDEREKSISELSDQ---YKQEKLILLQRCEETGNAYEDLS-----QKYKAA- 1046
Query: 283 LEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQL 342
+E + + L + S EN N + K A K + L E +++++L
Sbjct: 1047 -QEKNSKLECLLNECTSLCENRKNELEQLKEAFAK--EHQEFLTKLAFAEERNQNLMLEL 1103
Query: 343 SEVDKT-KEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRK 401
V + + E+T++ N +++ L+ E + + E K+Q K + + QENE +
Sbjct: 1104 ETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQ---KEVNDLLQENEQLMKVM 1160
Query: 402 LTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKR 461
T E +E E + V+E+ S E + K DLE + E ++ Y Q++ E
Sbjct: 1161 KTKHECQNLESEPIRNSVKERES---ERNQCNFKPQMDLEVK-EISLDSYNAQLVQLEAM 1216
Query: 462 GHDNWLAARTAERNLSDLRKE 482
+ L + +E+ L+ E
Sbjct: 1217 LRNKELKLQESEKEKECLQHE 1237
Score = 47.0 bits (110), Expect = 7e-05
Identities = 84/412 (20%), Positives = 165/412 (40%), Gaps = 54/412 (13%)
Query: 126 RSLEATCEKLSRSNSELED----------EILCLEKDLKEEKSKHSQQDELMADISKSIQ 175
+ +E C K S+ ++ED EI+ ++ ++ +++ +L+ S+
Sbjct: 716 KEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLV 775
Query: 176 SLEDESKSLKSQIAE-------AKIICKTFKMSEERRAIAIK-DALNENSQLQTSHKQLF 227
+ ED +SL + + A II + M ER ++ D +NS + +
Sbjct: 776 TNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSL 835
Query: 228 QQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDT 287
+ E K S+L KQ K E+ L E ++ + + L+EDT
Sbjct: 836 EFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAET---SQRISKLQEDT 892
Query: 288 TDDDNLELKVNSQWENGAN----LDDPPKGALKKLIHAAKLNVSLK-------------S 330
+ N+ + S EN L+D + ++ K N L+ S
Sbjct: 893 SAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLS 952
Query: 331 LEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSE--NIYFESEN-----QKLQQK 383
LE + II L++ + EELT+ L+ ASL E N+ +SE+ + ++
Sbjct: 953 LEKKEMSSIISLNK--REIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKS 1010
Query: 384 LKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEE 443
+ +++ Y++ ++ L ++ N + +K +EK S L L ++ + E
Sbjct: 1011 ISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNE 1070
Query: 444 LERTVHFYQKQVISY-------EKRGHDNWLAARTAERNLSDLRKENAHNKQ 488
LE+ + K+ + E+R + L T ++ L +N +N +
Sbjct: 1071 LEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSK 1122
Score = 45.4 bits (106), Expect = 2e-04
Identities = 98/474 (20%), Positives = 197/474 (41%), Gaps = 81/474 (17%)
Query: 59 LWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFE 118
L S +R+RL +++L L L E + L++ E E E + + E
Sbjct: 2299 LRNSIEKLRARLEADEKKQL-CVLQQLKESE----HHADLLKGRVENLERELEIARTNQE 2353
Query: 119 KAAAE------EARSLEATCEKLSRSNSELEDEILCL---EKDLKEEKSKHSQQDELMAD 169
AA E E +L+A E +++S LE +++ + +++L E K ++ +
Sbjct: 2354 HAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI 2413
Query: 170 ISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQ 229
I+ S +++ E + K Q+ +E+ + A++ LQT K+L ++
Sbjct: 2414 INSSFENILQEKEQEKVQM-------------KEKSSTAME-------MLQTQLKELNER 2453
Query: 230 EA------EVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHI----KTLTGHLPMMKDQ 279
A E K + L+ Q E K Q L++ +N+ ++ G + ++D
Sbjct: 2454 VAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDG 2513
Query: 280 AAVLEEDTTDDDNLELKVNSQWENGANLDDPP-KGALKKLIHAAKLNVSLKSLEGERNHI 338
LE+ + L+ ++ Q + + L + L K + N+ L++L E
Sbjct: 2514 KQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWK-----EQNLELRNLTVELEQ- 2567
Query: 339 IIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKL 398
++ + L + ++ LQ+ +L++E + + +K+ MT E +L
Sbjct: 2568 --KIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMT----AKETEL 2621
Query: 399 YRKLTVEENYRIEEEEKLS----RVEEKISHATEELETYRKLAKDL---EEELERTVHFY 451
R++ E +E+LS R+ ++ EE+++ + K+L EL++++
Sbjct: 2622 QREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCM 2681
Query: 452 QKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPN 505
K + EK G +R+E A + +L E E K + L D N
Sbjct: 2682 HKDQV--EKEG---------------KVREEIAEYQLRLHEAEKKHQALLLDTN 2718
Score = 45.1 bits (105), Expect = 3e-04
Identities = 73/370 (19%), Positives = 151/370 (40%), Gaps = 43/370 (11%)
Query: 138 SNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKT 197
S S+ ED K+++E K ++ L A K+ Q+L + + + IA +
Sbjct: 160 SGSKYEDLKEKYNKEVEERKRLEAEVKALQA--KKASQTLPQATMNHRD-IARHQASSSV 216
Query: 198 FKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQ 257
F +E+ L+ NSQ + A + G+ E+ + T + K A
Sbjct: 217 FSWQQEKTP----SHLSSNSQRTPIRRDF---SASYFSGE-QEVTPSRSTLQIGKRDANS 268
Query: 258 VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDN-LELKVNSQWENGANLDDPPKGALK 316
D + P + DQ ++ + N LEL++ + KG +
Sbjct: 269 SFFDNSSS--------PHLLDQLKAQNQELRNKINELELRLQGH-------EKEMKGQVN 313
Query: 317 KL----IHAAKLNVSL----KSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ--TQQASL 366
K + K V L K L R+ ++ ++ D+ + T + L+ T+ S
Sbjct: 314 KFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSC 373
Query: 367 QSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHA 426
Q +N ES L+QK+K + +QE + R + I+ + +L++ ++ +
Sbjct: 374 QRQNA--ESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNM 431
Query: 427 TEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKEN--- 483
L+ ++++LE + +++++ E+ + + R++ +++KEN
Sbjct: 432 HNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLL 491
Query: 484 -AHNKQKLTE 492
+H++QK E
Sbjct: 492 KSHSEQKARE 501
Score = 41.2 bits (95), Expect = 0.004
Identities = 57/307 (18%), Positives = 132/307 (42%), Gaps = 25/307 (8%)
Query: 71 YVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEA 130
+V + K+ A + L E ++ +K + +Q+E G + + E + EE +S +
Sbjct: 2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGE----LQLLLEEIKSSKD 2662
Query: 131 TCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQI-A 189
++L+ NSEL+ + C+ KD E++ K ++ +A+ + E + ++L
Sbjct: 2663 QLKELTLENSELKKSLDCMHKDQVEKEGKVREE---IAEYQLRLHEAEKKHQALLLDTNK 2719
Query: 190 EAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFE 249
+ ++ +T++ + + E L++S ++L K L + K T
Sbjct: 2720 QYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNS----LKATTQILEELKKTKM 2775
Query: 250 DSKVHAEQVLNDKE---NHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGAN 306
D+ + Q+ + E +K L ++++ +L+++ + +L+ + +
Sbjct: 2776 DNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELS-----QLQAAQEKQKTGT 2830
Query: 307 LDDPPKGALKKLIHAAKLNVSLKSLEGERN-----HIIIQLSEVDKTKEELTEHIKNLQT 361
+ D L I K + K+ E + ++I +++K KE L + +L +
Sbjct: 2831 VMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCS 2890
Query: 362 QQASLQS 368
QQ+ S
Sbjct: 2891 QQSKQDS 2897
Score = 40.0 bits (92), Expect = 0.008
Identities = 89/431 (20%), Positives = 167/431 (38%), Gaps = 52/431 (12%)
Query: 109 ESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEI----LCLEKDLKE-EKSKHSQQ 163
E +L A A+ LE+ CE +S +LE+++ + K+++E E+ S++
Sbjct: 1533 EENLTRKETPSAPAKGVEELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSER 1592
Query: 164 DELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSH 223
EL + + E + L S E + K E+ ++ ++ A + L S
Sbjct: 1593 QELDCLRKQYLSENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSS 1652
Query: 224 KQLF-----------QQEAEVWKGQVSELNKQKITFEDSKV---HAEQVLNDKENHIKTL 269
+ L + ++ K SE ++ + ++ A+Q LN I T
Sbjct: 1653 RSLLGIDTEDAIQGRNESCDISKEHTSETTERTPKHDVHQICDKDAQQDLNLDIEKI-TE 1711
Query: 270 TGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKL--------IHA 321
TG + + + DT + E K E + L AL + IH
Sbjct: 1712 TGAVKPTGECSGEQSPDTNYEPPGEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHN 1771
Query: 322 AKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQ 381
+L V K E ++ + + D+ E L +K L ++ L + + ++ +
Sbjct: 1772 LQLRV--KETSNENLRLLHVIEDRDRKVESLLNEMKELDSK---LHLQEVQLMTKIEACI 1826
Query: 382 QKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLE 441
+ KI+ E +EN L KL E + + +E L RV ET L DLE
Sbjct: 1827 ELEKIVGELKKENS-DLSEKL---EYFSCDHQELLQRV-----------ETSEGLNSDLE 1871
Query: 442 EELERTVHFYQKQVISYEKRGHDNWLAA-RTAERNLSDLRKENAHNKQKLTERELKFELL 500
+++ ++ + + +D+W E LS +R E A + + E E++
Sbjct: 1872 MHADKS---SREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVV 1928
Query: 501 EKDPNALDVSN 511
+ + L+ N
Sbjct: 1929 QTEKLCLEKDN 1939
Score = 38.1 bits (87), Expect = 0.031
Identities = 83/387 (21%), Positives = 153/387 (39%), Gaps = 40/387 (10%)
Query: 141 ELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED---ESKSLKSQIAEAKIICKT 197
ELE + L+K KE++ + Q D L A + K Q +E+ E +LK + IC++
Sbjct: 22 ELEGQ---LDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICES 78
Query: 198 FKMSEER--RAIAIKDA-LN-ENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKV 253
+ ++++ + +K++ +N + QL + KQ+ + E E+ K SEL + + +
Sbjct: 79 LEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQEL-KRCKSELERS----QQAAQ 133
Query: 254 HAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDN--------LELKVNSQWENGA 305
A+ LN K T L + + ED + N LE +V + A
Sbjct: 134 SADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKA 193
Query: 306 NLDDPPKGALKKLI--HAAKLNVSLKSLEGERNHIIIQLSEVD----------KTKEELT 353
+ P + I H A +V E +H+ ++E+T
Sbjct: 194 SQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVT 253
Query: 354 EHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEE 413
LQ + S + + S + L +LK + + +L +L E +
Sbjct: 254 PSRSTLQIGKRDANS-SFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQV 312
Query: 414 EKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAE 473
K ++ ++ A EL K+ +EL RT Y + Y + L T +
Sbjct: 313 NKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKY--TALEQKLKKLTED 370
Query: 474 RNLSDLRKENAH--NKQKLTERELKFE 498
+ E+A +QK+ E+E +F+
Sbjct: 371 LSCQRQNAESARCSLEQKIKEKEKEFQ 397
Score = 34.7 bits (78), Expect = 0.35
Identities = 92/461 (19%), Positives = 182/461 (39%), Gaps = 54/461 (11%)
Query: 82 LSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSE 141
L L E + LEK ++++ E + + E E+ + E + L+ ++ N +
Sbjct: 1552 LESLCEVYRQSLEK---LEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQ 1608
Query: 142 LEDEI----LCLEKDLKEEKSKHSQQDELMADISK-SIQSLEDESKSLKSQIAEAKIICK 196
+ ++ L +E L EK K ++Q L ++++ +Q L+ S+SL E I
Sbjct: 1609 WQQKLTSVTLEMESKLAAEK-KQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDAI--- 1664
Query: 197 TFKMSEERRAIAIKDALNENSQLQTSHK------QLFQQEAEVWKGQVSELNKQKITFED 250
K+ +E ++ H + QQ+ + +++E K T E
Sbjct: 1665 ---QGRNESCDISKEHTSETTERTPKHDVHQICDKDAQQDLNLDIEKITETGAVKPTGEC 1721
Query: 251 S-----KVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEE---DTTDDDNLELKVNSQWE 302
S + E DK L A V + + D NL+L+V
Sbjct: 1722 SGEQSPDTNYEPPGEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHNLQLRVKETSN 1781
Query: 303 NGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ 362
L + +K+ L +K L+ + + +QL + EL + + L+ +
Sbjct: 1782 ENLRLLHVIEDRDRKV---ESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKE 1838
Query: 363 QASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRK---------LTVEENYR---I 410
+ L + YF ++Q+L Q+++ + EM + V ++++ +
Sbjct: 1839 NSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFL 1898
Query: 411 EEEEKLSRVEEK---ISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWL 467
+ E +LSR+ + I H LE ++ + + LE+ QK ++ E+ L
Sbjct: 1899 DVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEE-----L 1953
Query: 468 AARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALD 508
+ T+ERN LR E +K T + E +++ L+
Sbjct: 1954 SVVTSERN--QLRGELDTMSKKTTALDQLSEKMKEKTQELE 1992
Score = 30.8 bits (68), Expect = 5.0
Identities = 23/105 (21%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
Query: 342 LSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRK 401
L ++ + + +L + K Q +Q L S + + QK++ + T +EN+ +L
Sbjct: 17 LQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQ-RLMEI 75
Query: 402 LTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELER 446
E + + +L E +++ +L + +K + LE+EL+R
Sbjct: 76 CESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKR 120
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 77.0 bits (188), Expect = 6e-14
Identities = 109/442 (24%), Positives = 189/442 (42%), Gaps = 56/442 (12%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEI 146
EEK K L K Q+ + S LE+ K + + LE KL ++L+D+I
Sbjct: 1019 EEKAKNLAKIRNKQEV-----MISDLEERL--KKEEKTRQELEKAKRKLDGETTDLQDQI 1071
Query: 147 LCLEKDLKEEKSKHSQQDELMADISKSIQSLEDES----------KSLKSQIAEAKIICK 196
L+ + E K + ++++E ++ ++ +DE+ + L++QIAE + +
Sbjct: 1072 AELQAQIDELKLQLAKKEE---ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFE 1128
Query: 197 TFKMSEERRAIAIKDALNENSQLQTSHKQLF-----QQEAEVWKGQ-VSELNKQKITFED 250
+ K S + +D E L+T + QQE + Q V+EL +K E+
Sbjct: 1129 SEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL--KKALEEE 1186
Query: 251 SKVHAEQVLNDKENH---IKTLTGHLPMMKDQAAVLEEDTT--DDDNLELKVNSQWENGA 305
+K H Q+ + ++ H ++ L+ L K A LE++ + DN EL +
Sbjct: 1187 TKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQV 1246
Query: 306 NLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQAS 365
+ K +K + A + K EG+R + E+ + +L + N+ T
Sbjct: 1247 KAESEHK---RKKLDAQVQELHAKVSEGDRLRV-----ELAEKASKLQNELDNVSTLLEE 1298
Query: 366 LQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISH 425
+ + I F + L+ +L+ E QE + KL + R EEEK S E++
Sbjct: 1299 AEKKGIKFAKDAASLESQLQDTQELLQEETRQ---KLNLSSRIRQLEEEKNSLQEQQ--- 1352
Query: 426 ATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAH 485
EE E RK LE+ V Q Q+ +K+ D+ + E L K+
Sbjct: 1353 --EEEEEARK-------NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEA 1403
Query: 486 NKQKLTERELKFELLEKDPNAL 507
Q+L E+ L ++ LEK N L
Sbjct: 1404 LSQRLEEKALAYDKLEKTKNRL 1425
Score = 69.7 bits (169), Expect = 1e-11
Identities = 102/477 (21%), Positives = 204/477 (42%), Gaps = 50/477 (10%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDAS-----FEKAAAEEARSLEA 130
Q+L A +S + +L EK S +Q E + V + LE+A F K AA L+
Sbjct: 1262 QELHAKVSEGDRLRVELAEKASKLQNELDN--VSTLLEEAEKKGIKFAKDAASLESQLQD 1319
Query: 131 TCEKL---SRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQ 187
T E L +R L I LE++ + + +++E ++ K + +L+ + K +
Sbjct: 1320 TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK 1379
Query: 188 IAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVS-ELNKQKI 246
+ + T + EE + +KDA + +L+ K L + E K ++ EL+ +
Sbjct: 1380 VDDD---LGTIESLEEAKKKLLKDAEALSQRLE--EKALAYDKLEKTKNRLQQELDDLTV 1434
Query: 247 TFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGAN 306
+ H QV ++ E K L K +A E+ D E + + +
Sbjct: 1435 DLD----HQRQVASNLEKKQKKFDQLLAEEKSISARYAEER---DRAEAEAREKETKALS 1487
Query: 307 LDDPPKGALKKLIHAAKLNVSLKS----LEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ 362
L + AL+ + N L++ L ++ + + E++K+K L + ++ ++TQ
Sbjct: 1488 LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ 1547
Query: 363 QASLQSENIYFESENQKLQQKLKIMTEFYQ----------ENEMKLYRKLTVEENYRIEE 412
L+ E E +L+ ++ M ++ E + +L K E +E+
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED 1607
Query: 413 EEKLSRV----EEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKR------G 462
E K + ++K+ ++LE + A +E+ + + Q Q+ Y++
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARAS 1667
Query: 463 HDNWLA-ARTAERNLSDLRKENAHNKQKL--TERELKFELLEKDPNALDVSNTAFGR 516
D A ++ +E+ L L E +++L +ER + E+D A +++N+A G+
Sbjct: 1668 RDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGK 1724
Score = 66.2 bits (160), Expect = 1e-10
Identities = 113/538 (21%), Positives = 225/538 (41%), Gaps = 108/538 (20%)
Query: 60 WRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESS--LEDASF 117
WR F V+ L V R+++ L EE K+ EK + ++ E E E + LE+ +
Sbjct: 835 WRVFTKVKPLLQVTRQEE---ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI 891
Query: 118 EKAAAEEARSLEATCE----KLSRSNSELEDEILCLEKDLKEEKSKH----SQQDELMAD 169
+ L A E +L+ ELE+ + LE ++EE+ ++ +++ ++ A
Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
Query: 170 ISKSIQSLEDESKS-----LKSQIAEAKI--ICKTFKMSEERRAIAIKDALNENSQLQTS 222
I + L++E + L+ AEAKI + + + E++ + IK+ ++
Sbjct: 952 IQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAEC 1011
Query: 223 HKQLFQQEAEVWKGQVSELNKQKITFED-----------------SKVHAEQVLNDKENH 265
QL ++E E K NKQ++ D +K + D ++
Sbjct: 1012 SSQLAEEE-EKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQ 1070
Query: 266 IKTLTGHLPMMKDQAAVLEEDTT------DDDNL-----------------ELKVNSQWE 302
I L + +K Q A EE+ DD+ L EL+ + + E
Sbjct: 1071 IAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130
Query: 303 NGA-NLDDPPKGALKKLIHAAKLNV--------SLKSLEGERNHIIIQLSEV--DKTK-- 349
+ N + K L + + A K + + + L +R + +L + ++TK
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH 1190
Query: 350 ---------------EELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQEN 394
EEL+E ++ + +A+L+ E++N++L ++K++ + E+
Sbjct: 1191 EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAES 1250
Query: 395 EMK----------LYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYR----KLAKD- 439
E K L+ K++ + R+E EK S+++ ++ + + LE K AKD
Sbjct: 1251 EHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDA 1310
Query: 440 --LEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTEREL 495
LE +L+ T Q++ + +K + + E+N ++E +K E+++
Sbjct: 1311 ASLESQLQDTQELLQEE--TRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Score = 65.9 bits (159), Expect = 1e-10
Identities = 93/408 (22%), Positives = 178/408 (43%), Gaps = 59/408 (14%)
Query: 123 EEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESK 182
E+ +E E++ R + +L +E L + L+ E ++ +E+ A ++ Q LE+
Sbjct: 866 EKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILH 925
Query: 183 SLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELN 242
L+S++ E EER I NE ++Q +H Q +++ + +G +L
Sbjct: 926 DLESRVEE----------EEERNQI----LQNEKKKMQ-AHIQDLEEQLDEEEGARQKLQ 970
Query: 243 KQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWE 302
+K+T E E+ + E+ +M+D+ A +++ E
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEE----------E 1020
Query: 303 NGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ 362
NL K K+ + + L LK E R E++K K +L +LQ Q
Sbjct: 1021 KAKNL---AKIRNKQEVMISDLEERLKKEEKTR-------QELEKAKRKLDGETTDLQDQ 1070
Query: 363 QASLQSE----NIYFESENQKLQQKLKIMTE--FYQENEMKLYRKL--TVEENYRIEEEE 414
A LQ++ + + ++LQ L + ++ N +K+ R+L + E E E
Sbjct: 1071 IAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130
Query: 415 KLSR--VEEKISHATEELETYRKLAKDLEEELERT-----VHFYQKQVISYEKRGHDNWL 467
K SR E++ +EELE L +LE+ L+ T + ++Q ++ K+ +
Sbjct: 1131 KASRNKAEKQKRDLSEELEA---LKTELEDTLDTTAAQQELRTKREQEVAELKKALEE-- 1185
Query: 468 AARTAERNLSDLRKENAHNKQKLT---ERELKFEL-LEKDPNALDVSN 511
+ E + D+R+ +A ++L+ E+ +F+ LEK+ L+ N
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDN 1233
Score = 59.3 bits (142), Expect = 1e-08
Identities = 77/368 (20%), Positives = 147/368 (39%), Gaps = 40/368 (10%)
Query: 100 QKEYEGYEVESSLEDASFEKAAAE-EARSLEATCEKLSRSNSELEDEILCLEKDLKEEKS 158
+KE + + +LE+A K E + + L A E L S ++ + LEK + +
Sbjct: 1480 EKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQ 1539
Query: 159 KHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI-----ICKTFKMSEERRAIAIKDAL 213
+ + + ++ +Q+ ED L+ + K + + +EE++ + IK
Sbjct: 1540 QVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVR 1599
Query: 214 NENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHL 273
++L+ KQ V+ K +I +D + E ++ IK L
Sbjct: 1600 ELEAELEDERKQRALA--------VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQ 1651
Query: 274 PMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEG 333
MKD LEE D + + + +L+ +L L S E
Sbjct: 1652 AQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE----------AEILQLQEELASSER 1701
Query: 334 ERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQE 393
R H ++ ++EL + I N + +++L E E+ +L+++L+ ++
Sbjct: 1702 ARRH-------AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELE-----EEQ 1749
Query: 394 NEMKL----YRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVH 449
+ M+L +RK T++ + E +K +A ++LE K K +ELE V
Sbjct: 1750 SNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVK 1809
Query: 450 FYQKQVIS 457
K IS
Sbjct: 1810 SKFKATIS 1817
Score = 35.8 bits (81), Expect = 0.16
Identities = 44/186 (23%), Positives = 82/186 (44%), Gaps = 28/186 (15%)
Query: 83 SGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA-----------AAEE--ARSLE 129
S L++EK +L + + +++E E + L + F K AAE A+ +
Sbjct: 1725 SALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD 1784
Query: 130 ATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIA 189
++L R N EL+ ++ LE +K + + L A I + + LE E+ K + A
Sbjct: 1785 NARQQLERQNKELKAKLQELEGAVKSKFK--ATISALEAKIGQLEEQLEQEA---KERAA 1839
Query: 190 EAKIICKTFKM---------SEERRAIAIKDALNE-NSQLQTSHKQLFQQEAEVWKGQVS 239
K++ +T K E R A K+ + + N++++ +QL + E E + S
Sbjct: 1840 ANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANAS 1899
Query: 240 ELNKQK 245
Q+
Sbjct: 1900 RRKLQR 1905
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 75.9 bits (185), Expect = 1e-13
Identities = 105/483 (21%), Positives = 192/483 (39%), Gaps = 45/483 (9%)
Query: 63 FRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA 122
F ++ L +K AT+ E + L + +KE E V E +
Sbjct: 837 FFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQ 896
Query: 123 EEARSL---EATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED 179
E +L E CE L +S + LE +KE + +++E+ +++ ++LED
Sbjct: 897 SETENLMDAEERCEGLIKSK-------ILLEAKVKELTERLEEEEEMNSELVAKKRNLED 949
Query: 180 ESKSLKSQIAEAKIIC------------KTFKMSEERRAIA--IKDALNENSQLQTSHKQ 225
+ SLK I + ++ K +SEE A+ I E LQ +H+Q
Sbjct: 950 KCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQ 1009
Query: 226 L---FQQEAEVWKGQV---SELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQ 279
Q E + G + ++L +Q E S +++ D E + L G L M ++
Sbjct: 1010 TLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQES 1069
Query: 280 AAVLEEDTTD-DDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGE---- 334
LE D ++ L+ K + A +DD +L+ +L ++ LE E
Sbjct: 1070 IMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAE 1129
Query: 335 ---RNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFY 391
R I Q S++ + EE++E ++ ++ N E+E QK+++ L+ T +
Sbjct: 1130 HTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQH 1189
Query: 392 QENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELE-TYRKLAKDLE------EEL 444
+ L +K E+ + L RV++K+ EL+ +A ++E +
Sbjct: 1190 EATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNI 1249
Query: 445 ERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDP 504
ERT + Q + + + L+ +N ++ E+E L K
Sbjct: 1250 ERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSK 1309
Query: 505 NAL 507
AL
Sbjct: 1310 QAL 1312
Score = 67.8 bits (164), Expect = 4e-11
Identities = 106/441 (24%), Positives = 188/441 (42%), Gaps = 47/441 (10%)
Query: 99 IQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKS 158
IQ+ E E + L E A E + + C L ++ L+ E+ L +DL+ +
Sbjct: 1384 IQRTEELEEAKKKLAQRLQE--AEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHT 1441
Query: 159 KHSQQDELMADISKSI----QSLEDESKSLKSQIAEAKIIC-KTFKMSEERRAIA--IKD 211
+ D+ + K + Q L++ L++ E++ + + FKM + ++
Sbjct: 1442 ACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLET 1501
Query: 212 ALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHI----- 266
EN LQ L +Q AE K + E K K E K + L + E +
Sbjct: 1502 LRRENKNLQEEISDLTEQIAETGKN-LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES 1560
Query: 267 KTLTGHLPMMKDQAAVLEEDTTDDDNLE-LKVNSQWENGANLDDPPKGALKKLIHAAKLN 325
K L L + + ++ + + D+ +E LK NSQ A L ++ A +L
Sbjct: 1561 KILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEA-LQSVLDAEIRSRNDALRLK 1619
Query: 326 VSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFES---ENQKLQQ 382
K +EG+ N + IQL + ++ E K+L+T Q L+ ++ + N+ L++
Sbjct: 1620 ---KKMEGDLNEMEIQLGH---SNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKE 1673
Query: 383 KLKIMTE-----FYQENEMKLYRKLTVEENYRIEEEEKL---SRVEEKISHATEELETYR 434
+L I+ + EMK+ + T E R+ E+E L RV+ S T + T +
Sbjct: 1674 QLAIVERRNGLLLEELEEMKVALEQT-ERTRRLSEQELLDASDRVQLLHSQNTSLINTKK 1732
Query: 435 KLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKE---NAHNKQ--- 488
KL D+ + + Q+ + EK AA AE +L+KE +AH ++
Sbjct: 1733 KLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAE----ELKKEQDTSAHLERMKK 1788
Query: 489 --KLTERELKFELLEKDPNAL 507
+ T ++L+ L E + AL
Sbjct: 1789 NLEQTVKDLQHRLDEAEQLAL 1809
Score = 60.8 bits (146), Expect = 5e-09
Identities = 85/396 (21%), Positives = 177/396 (44%), Gaps = 54/396 (13%)
Query: 86 IEEKCKLLEK------FSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSN 139
+E+KC L++ +L + E E + E+ +++ S EE +LE KL++
Sbjct: 947 LEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLS------EEMTALEENISKLTKEK 1000
Query: 140 SELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLE---DESKSLKSQIAEAKIICK 196
L++ DL+ E+ K + ++ A + + LE ++ K L++ + AK +
Sbjct: 1001 KSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLE 1060
Query: 197 -TFKMSEERRAIAIKDALNENSQLQTSHK----QLFQQEAEVWKGQVSELNKQKITFE-- 249
KMS+E +I D N+ Q++ K +L Q +A++ QV L QK E
Sbjct: 1061 GDLKMSQE----SIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQ 1116
Query: 250 ------DSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWE- 302
+ ++ AE L K I+ L ++ + E+ + + ++++N + E
Sbjct: 1117 ARIEELEEEIEAEHTLRAK---IEKQRSDLARELEEISERLEEASGATSAQIEMNKKREA 1173
Query: 303 ---------NGANLDDPPKGAL---KKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKE 350
A L A K+ A+L + +L+ + + + SE+ +
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1233
Query: 351 ELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTV--EENY 408
++ +I+ L +++++ E + +++ K + T+ + M+ R T E ++
Sbjct: 1234 DMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSH 1293
Query: 409 RIEEEEKL-SRVEEKISHATEELETYRKLAKDLEEE 443
R+EE+E L S++ + T++LE +L + +EEE
Sbjct: 1294 RVEEKESLISQLTKSKQALTQQLE---ELKRQMEEE 1326
Score = 53.1 bits (126), Expect = 9e-07
Identities = 81/371 (21%), Positives = 166/371 (44%), Gaps = 62/371 (16%)
Query: 107 EVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQ--- 163
EVE SLE EE++ L E LS+ SEL+ +++ EKD + E+ K + Q
Sbjct: 1550 EVEGSLEH--------EESKILRVQLE-LSQVKSELDRKVI--EKDEEIEQLKRNSQRAA 1598
Query: 164 DELMADISKSIQSLEDE---SKSLKSQIAEAKIIC--KTFKMSEERRAIAIKDALNENSQ 218
+ L + + I+S D K ++ + E +I +M+E ++ + ++SQ
Sbjct: 1599 EALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQ 1658
Query: 219 LQT-----SHKQLFQQEAEVWKGQ---VSELNKQKITFEDSKVH---AEQVLNDKENHIK 267
L S++ L +Q A V + + EL + K+ E ++ +EQ L D + ++
Sbjct: 1659 LHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQ 1718
Query: 268 TLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVS 327
L + + LE D + +V + + N ++ K K + AA +
Sbjct: 1719 LLHSQNTSLINTKKKLEADIAQ---CQAEVENSIQESRNAEEKAK---KAITDAAMMAEE 1772
Query: 328 LKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIM 387
LK + H+ ++ K+ L + +K+LQ + ++E + + +++Q+ +
Sbjct: 1773 LKKEQDTSAHL-------ERMKKNLEQTVKDLQHRLD--EAEQLALKGGKKQIQKLENRV 1823
Query: 388 TEFYQENEMKL--------------YRKLTVEENYRIEEEEK-LSRVEEKISHATEELET 432
E ENE+ + Y + E Y+ EE+ K + R+++ + ++++
Sbjct: 1824 REL--ENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKS 1881
Query: 433 YRKLAKDLEEE 443
Y++ A++ EE+
Sbjct: 1882 YKRQAEEAEEQ 1892
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 75.5 bits (184), Expect = 2e-13
Identities = 103/474 (21%), Positives = 208/474 (43%), Gaps = 81/474 (17%)
Query: 76 QKLGATLSGLIEEK----CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT 131
++L + L++EK C++ E +QK + + D + E E
Sbjct: 1357 EELHHNIDDLLQEKKSLECEVEELHRTVQKRQQ----QKDFIDGNVESLMTE------LE 1406
Query: 132 CEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEA 191
EK + + ++ DEI C+EK L + +S+ + D L+A+ + ++++K+ + +A
Sbjct: 1407 IEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA 1466
Query: 192 K-IICKTFKMSEERRAIAIKDALN------ENSQLQTSHKQLFQ---QEAEVWKG----- 236
K + +T +EE A + A+N + LQ K L Q ++ E+ K
Sbjct: 1467 KRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIV 1526
Query: 237 -------QVSELNKQKITFEDSKVHAE-QVLNDKENHIKTLTGHLPMMKDQAAVLEEDTT 288
Q K+K+T E K+ + ++ E+H HL ++K+ +L+
Sbjct: 1527 AAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDH------HLQVLKESEVLLQAKRA 1580
Query: 289 DDDNLELKVNSQWENGANLDDPPKGALKKLIH---------AAKLNVSLKSLEGERNHII 339
+ + L+ +V SQ + A L D G K+ +H A L +L+ E E
Sbjct: 1581 ELEKLKSQVTSQQQEMAVL-DRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKC 1639
Query: 340 IQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKL- 398
+ EV EEL+ L Q + +++ + E +K ++ L+++ +++ +L
Sbjct: 1640 NHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELK 1699
Query: 399 ------------YRKLTVEENYRIEEEEK--LSRVEEKISHATEELETYRKLAKDLEEEL 444
+ L ++ + R+ E EK ++ +EEK+ ELE +++++ + E+
Sbjct: 1700 NILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKL-----ELENLQQISQQQKGEI 1754
Query: 445 ERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDL---RKENAHNKQKLTEREL 495
E +QKQ++ +KR + A A ++ + KE+ K + E++L
Sbjct: 1755 E-----WQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKL 1803
Score = 66.2 bits (160), Expect = 1e-10
Identities = 73/389 (18%), Positives = 175/389 (44%), Gaps = 34/389 (8%)
Query: 86 IEEKCKLLEK-FSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELED 144
++EKC + EK + ++ E S +E ++ EK R L+ ++L+R L +
Sbjct: 1792 LQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELN-VRKLQQELDQLNRDKLSLHN 1850
Query: 145 EILCLEKDLKEEKSKHSQQDELMADI--------------SKSIQSLEDESKSLKSQIAE 190
+I +++ L+E++ + E +A++ +K L E L+ I+E
Sbjct: 1851 DISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISE 1910
Query: 191 AKII---CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKIT 247
C+ + +++++ +++ + EN + +FQ+ + + + S+L K+T
Sbjct: 1911 WANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVT 1970
Query: 248 FEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANL 307
++ + E+ L D+++ + + + +++ L+E+ ++LE K SQ + L
Sbjct: 1971 LKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLE-KTLSQTKR--QL 2027
Query: 308 DDPPKGALKKLIHAAKLNVSLKSLEGE----RNHIIIQLSEVDKTKEELTEHIKNLQTQQ 363
+ + ++K L S+ + RN + + + +K L E +K Q+
Sbjct: 2028 SEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALK---IQR 2084
Query: 364 ASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEEN---YRIEEEEKLSRVE 420
+ L+ + + EN +Q+++ + Q+N + R+L E N Y E +K +
Sbjct: 2085 SQLEKNLLEQKQENSCIQKEMATIELVAQDNHERA-RRLMKELNQMQYEYTELKKQMANQ 2143
Query: 421 EKISHATEEL-ETYRKLAKDLEEELERTV 448
+ + E+ + R L ++++E+ ++
Sbjct: 2144 KDLERRQMEISDAMRTLKSEVKDEIRTSL 2172
Score = 65.1 bits (157), Expect = 2e-10
Identities = 104/451 (23%), Positives = 196/451 (43%), Gaps = 62/451 (13%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEA--RSLEATCEKLSRSNSEL 142
L ++K KL E+ +QK+ E E ED + E ++ A EKL +
Sbjct: 1536 LSKKKEKLTEELQKLQKDIEMAERN---EDHHLQVLKESEVLLQAKRAELEKLKSQVTSQ 1592
Query: 143 EDEILCLEKDLKEEKSK-HSQQDELM---ADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
+ E+ L++ L +K + H Q ++ AD+ ++++ E E + I E K + +
Sbjct: 1593 QQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEEL 1652
Query: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDS----KVH 254
+ + I + +QL T KQ ++E E + + +++K K ++ ++
Sbjct: 1653 SFQKGELNVQISE---RKTQL-TLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLE 1708
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGA 314
++ K H + ++ + K Q AVLEE LEL EN + KG
Sbjct: 1709 NHELQGLKLQHDQRVS---ELEKTQVAVLEE------KLEL------ENLQQISQQQKGE 1753
Query: 315 L---KKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHI-----KNLQTQQA-S 365
+ K+L+ K + + E ++ + K KE+L E K QT++ +
Sbjct: 1754 IEWQKQLLERDKREIERMTAESRALQSCVEC--LSKEKEDLQEKCDIWEKKLAQTKRVLA 1811
Query: 366 LQSENIYFESEN-QKLQQKL-KIMTEFYQEN--EMKLYRKLTVEENYRIEEEEKLSRVEE 421
EN E N +KL+ + K+ E Q N ++ L+ ++ + E+ E ++ ++E
Sbjct: 1812 AAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQE 1871
Query: 422 KISHATEELETYRKLAKDLEEELERTVHF---------YQKQVISYEKRGHDNWLAARTA 472
++++ + L LAK ++ L T H QK + + R D T
Sbjct: 1872 ELANVQDHLN----LAK--QDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETK 1925
Query: 473 ERNLSDLRKENAHNKQKLTERELKFELLEKD 503
++ L L+ E NK KL ++E+ F+ L+K+
Sbjct: 1926 QQQLQVLQNEIEENKLKLVQQEMMFQRLQKE 1956
Score = 60.5 bits (145), Expect = 6e-09
Identities = 100/490 (20%), Positives = 199/490 (40%), Gaps = 81/490 (16%)
Query: 75 EQKLGATLSGLIEEKCKL---LEKFSLIQKEYEGYEVESSLEDASFEK---AAAEEARSL 128
E+ L L + + K +L L+ L E +G +++ + EK A EE L
Sbjct: 1681 EENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLEL 1740
Query: 129 EATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQI 188
E + + E+E + LE+D +E E M S+++QS + K +
Sbjct: 1741 ENLQQISQQQKGEIEWQKQLLERDKREI--------ERMTAESRALQSCVECLSKEKEDL 1792
Query: 189 AEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITF 248
E I + K+++ +R +A A ENS+++ S+ + + + ++ +LN+ K++
Sbjct: 1793 QEKCDIWEK-KLAQTKRVLA---AAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSL 1848
Query: 249 EDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEED---TTDDDNLEL-------KVN 298
+ +Q L +K + +L L ++D + ++D TT ++ L K
Sbjct: 1849 HNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDI 1908
Query: 299 SQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKN 358
S+W N +D K K +L V +E + ++ Q + ++E
Sbjct: 1909 SEWAN--RFEDCQKEEETK---QQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESK 1963
Query: 359 LQTQQASLQSENIYFESE----NQKLQQKL-KIMT---------------EFYQENEMKL 398
L+T + +L+ + E E KL Q L K++ E ++ +
Sbjct: 1964 LETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQT 2023
Query: 399 YRKLTVEENYRIEEEEKL-------------------------SRVEEKISHATEELETY 433
R+L+ E +E+ +L + E++++ E L+
Sbjct: 2024 KRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQ 2083
Query: 434 R-KLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAH-NKQKLT 491
R +L K+L E+ + QK++ + E DN AR + L+ ++ E KQ
Sbjct: 2084 RSQLEKNLLEQKQEN-SCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMAN 2142
Query: 492 ERELKFELLE 501
+++L+ +E
Sbjct: 2143 QKDLERRQME 2152
Score = 50.8 bits (120), Expect = 5e-06
Identities = 76/336 (22%), Positives = 136/336 (40%), Gaps = 55/336 (16%)
Query: 123 EEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESK 182
+EA LE EK + + + EI L+ + SK + + A S Q L+ +K
Sbjct: 510 QEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNK 569
Query: 183 S---LKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVS 239
L+S++ E I+ + K +EE IKD + ++ Q + + +++ E G +S
Sbjct: 570 QYQQLESRLDE--ILSRIAKETEE-----IKDLEEQLTEGQIAANEALKKDLE---GVIS 619
Query: 240 ELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDN------- 292
L + T + A+ + +TL L ++ + LE D +N
Sbjct: 620 GLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAE 679
Query: 293 LELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEEL 352
LE + Q E A+L +G L + A+L L + E N + KEEL
Sbjct: 680 LESALQEQHEVNASLQQT-QGDLSA--YEAELEARLNLRDAEANQL----------KEEL 726
Query: 353 TEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEE 412
+ + Q +Q++LQ+E E E Q L+ L + + E+
Sbjct: 727 EKVTRLTQLEQSALQAE---LEKERQALKNALG-------------------KAQFSEEK 764
Query: 413 EEKLSRVEEKISHATEELETYRKLAKDLEEELERTV 448
E++ S + K+ H ++ ++ KD + L V
Sbjct: 765 EQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVV 800
Score = 46.6 bits (109), Expect = 9e-05
Identities = 80/400 (20%), Positives = 169/400 (42%), Gaps = 45/400 (11%)
Query: 80 ATLSGLIEEKCKLLEKFSLIQKEYEGYEVES----SLEDASFEKAAAEEARSLEATCEKL 135
A L ++E+ ++ Q + YE E +L DA + E + T +
Sbjct: 678 AELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQ 737
Query: 136 SRSNSELEDEILCLEKDL-KEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAK-- 192
S +ELE E L+ L K + S+ +Q+ +++ ++ L+D++ LK Q+ + +
Sbjct: 738 SALQAELEKERQALKNALGKAQFSEEKEQEN--SELHAKLKHLQDDNNLLKQQLKDFQNH 795
Query: 193 IICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSK 252
+ + A D L +L T + ++V +++L KQ F +
Sbjct: 796 LNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNI-HSPSDVLGKSLADLQKQ---FSEIL 851
Query: 253 VHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTD--DDNLELKVN-SQWENGANLDD 309
++ ++ + + L + + +++ A +E+ + LE ++N + ++ A +
Sbjct: 852 ARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQ 911
Query: 310 PPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ----TQQAS 365
++ IH + N LKS+E + +QL E D+ KE + ++ L+ + A
Sbjct: 912 -----MENEIHYLQEN--LKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAK 964
Query: 366 LQSENIYFESENQKLQQ------KLKIMTEFYQENEMK----LYRKLTVEENYRIEEEEK 415
Q + + E +KL++ KL ++++K K+ E ++E E+
Sbjct: 965 SQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAER 1024
Query: 416 LSR----VEEKISHATEELETYRKLAKDLEE----ELERT 447
SR ++ A E+E + L + E E+E+T
Sbjct: 1025 FSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEKT 1064
Score = 43.5 bits (101), Expect = 7e-04
Identities = 65/383 (16%), Positives = 160/383 (41%), Gaps = 48/383 (12%)
Query: 142 LEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMS 201
LE+E+ LE ++ KSK ++ + A +S + +E+ ++ + E K + ++
Sbjct: 1321 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSL--ECEVE 1378
Query: 202 EERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLND 261
E R + Q QQ+ + G V L ++ E S H E ++++
Sbjct: 1379 ELHRTV-----------------QKRQQQKDFIDGNVESL-MTELEIEKSLKHHEDIVDE 1420
Query: 262 KENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKV-----------NSQWENGANLDDP 310
E KTL +++ +L E ++ + K S + ++ ++
Sbjct: 1421 IECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEEL 1480
Query: 311 PKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSEN 370
+ A + ++ K + L+SL+ + + + ++ +E+ + + + L +
Sbjct: 1481 ERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKK 1540
Query: 371 IYFESENQKLQQKLKIM-------TEFYQENEMKLYRKLTVEENYRIE---EEEKLSRVE 420
E QKLQ+ +++ + +E+E+ L K E + + ++++++ ++
Sbjct: 1541 EKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLD 1600
Query: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
++ H EEL + + +L+ + + +V EK H R + L +L
Sbjct: 1601 RQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVT--EKCNH-----IREVKSLLEELS 1653
Query: 481 KENAHNKQKLTERELKFELLEKD 503
+ +++ER+ + L++++
Sbjct: 1654 FQKGELNVQISERKTQLTLIKQE 1676
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 74.3 bits (181), Expect = 4e-13
Identities = 96/399 (24%), Positives = 176/399 (44%), Gaps = 66/399 (16%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQK--EYEGYEVESSLEDASFEKAAAEEARSLEAT 131
+E++L A L+ L +E + +K + ++K E EG+ + ED E+AA +A +
Sbjct: 1088 KEEELQAALARLDDE---IAQKNNALKKIRELEGH-ISDLQEDLDSERAARNKAEKQKRD 1143
Query: 132 C-EKLSRSNSELED-----------------EILCLEKDLKEEKSKHSQQDELMADISKS 173
E+L +ELED E+ L+K L EE H Q + M K
Sbjct: 1144 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ--KH 1201
Query: 174 IQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV 233
Q++E+ ++ L+ Q AK K + E+ + L Q KQ + + +
Sbjct: 1202 AQAVEELTEQLE-QFKRAKANLDKNKQTLEKENADLAGELRVLGQA----KQEVEHKKKK 1256
Query: 234 WKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL 293
+ QV EL + E ++ ++ +N ++++TG L + +A L +D
Sbjct: 1257 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS---- 1312
Query: 294 ELKVNSQWENGANLDDPPKGALKKLIHAAKLNVS--LKSLEGERNHIIIQLSEVDKTKEE 351
++SQ ++ L KLNVS L+ LE ERN + QL E + K+
Sbjct: 1313 ---LSSQLQDTQELLQEET--------RQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQN 1361
Query: 352 LTEHIKNLQTQQASLQSENIYF-------ESENQKLQQKLKIMTEFYQENEMKLYRKLTV 404
L HI L Q + + + F E ++ Q++++ +T+ Y+E + Y KL
Sbjct: 1362 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKL-- 1418
Query: 405 EENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEE 443
E+ +R+++++ +L+ R+L +LE++
Sbjct: 1419 --------EKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Score = 63.9 bits (154), Expect = 5e-10
Identities = 99/453 (21%), Positives = 185/453 (40%), Gaps = 74/453 (16%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSL---EATCEKLSRSNSELE 143
E K K LE L+ + + S E E+ ++ +L E + L++ ++ E
Sbjct: 977 EAKIKKLEDEILVMDDQNN---KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEE 203
I LE LK+E+ + ++L + ++ L++QIAE K+ + K EE
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM--QLAKKEEE 1091
Query: 204 RRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKE 263
+A A+ +E +Q + K++ + E G +S+L + + ++ AE+ D
Sbjct: 1092 LQA-ALARLDDEIAQKNNALKKIRELE-----GHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 264 NHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAK 323
++ L L EDT D + ++ ++ E + LKK +
Sbjct: 1146 EELEALKTEL-----------EDTLDSTATQQELRAKREQEVTV-------LKKALDEET 1187
Query: 324 LNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQK 383
+ + E + H + EELTE ++ + +A+L E EN L +
Sbjct: 1188 RSHEAQVQEMRQKHA--------QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1239
Query: 384 LKIMTEFYQENEMK----------LYRKLTVEENYRIEEEEKLSRVEEKISHATEELETY 433
L+++ + QE E K L K + E R E +K+ +++ ++ T L
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299
Query: 434 R----KLAKD---LEEELERTVHFYQKQV------------ISYEKRGHDNWL-----AA 469
KLAKD L +L+ T Q++ + E+ + L A
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 470 RTAERNLSDLRKENAHNKQKLTERELKFELLEK 502
+ ER++S L + + +K+KL + E LE+
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392
Score = 55.8 bits (133), Expect = 1e-07
Identities = 102/491 (20%), Positives = 197/491 (40%), Gaps = 89/491 (18%)
Query: 91 KLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE---KLSRSNSELEDEIL 147
+LL + I +Y + E E A AR+LE E +L R+N L+ E+
Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM- 1513
Query: 148 CLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFK-------- 199
+DL K D+ K++ LE ++L++Q+ E K + +
Sbjct: 1514 ---EDLVSSKD----------DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
Query: 200 ------------MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV----WKGQVSELNK 243
+ R + +D NE + Q +QL + E E+ + ++ K
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL-QRQLHEYETELEDERKQRALAAAAK 1619
Query: 244 QKI--TFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD---------- 291
+K+ +D ++ A+ + +E IK L MKD LE+ D
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
Query: 292 ----NLELKVNSQWENGANLDDPPKGA-LKKLIHAAKLNVSL---KSLEGERNHIIIQLS 343
+LE + E+ A + K A L+K A +L SL +L+ E+ + +++
Sbjct: 1680 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739
Query: 344 EVDKTKEE--------------LTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
++++ EE T+ + L + A+ +S ES Q+L+++ K +
Sbjct: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
Query: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELER--- 446
E E + K ++ E K++++EE++ E + K K +++L+
Sbjct: 1800 KLHEMEGAVKSKF---KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILL 1856
Query: 447 TVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNA 506
V +K Y+++ + +R L + +E+ Q++ K L+++ +
Sbjct: 1857 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES----QRINANRRK---LQRELDE 1909
Query: 507 LDVSNTAFGRE 517
SN A GRE
Sbjct: 1910 ATESNEAMGRE 1920
Score = 43.1 bits (100), Expect = 0.001
Identities = 78/370 (21%), Positives = 141/370 (38%), Gaps = 37/370 (10%)
Query: 86 IEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELE-- 143
+E++ K + +K+ EG + L+ S K E + L ++ ELE
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 144 ----DEILCLEKDLKEEKSKHSQQD-----ELMADISKSIQSLEDESKSLKSQIAEAKII 194
DEI K+ E+K+K + D E +A ++ + + E + L ++A + +
Sbjct: 1665 RASRDEIFATAKE-NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA-SSLS 1722
Query: 195 CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVH 254
+ E+RR A L E + + + + Q +L+ + T +
Sbjct: 1723 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1782
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGA 314
E E K L L M + AV + + LE K+ +Q E + K A
Sbjct: 1783 NESARQQLERQNKELRSKLHEM--EGAVKSKFKSTIAALEAKI-AQLEEQVEQEAREKQA 1839
Query: 315 LKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTE-------HIKNLQTQQASLQ 367
K SLK + + I++Q+ + K E+ E +K L+ Q +
Sbjct: 1840 ATK---------SLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1890
Query: 368 SENIYFESENQKLQQKLKIMTEFYQE-----NEMKLYRKLTVEENYRIEEEEKLSRVEEK 422
E+ + +KLQ++L TE + N +K + E ++ RV E
Sbjct: 1891 EESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIEN 1950
Query: 423 ISHATEELET 432
+ EE +T
Sbjct: 1951 ADGSEEETDT 1960
Score = 37.4 bits (85), Expect = 0.054
Identities = 42/173 (24%), Positives = 73/173 (42%), Gaps = 12/173 (6%)
Query: 344 EVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENE---MKLYR 400
E+ KTKE + + + L+ ++ E LQ++L+ TE Y E E ++L
Sbjct: 860 ELQKTKERQ----QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAA 915
Query: 401 KLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEK 460
K E E E +L E++ E + + DLEE+LE QK + EK
Sbjct: 916 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK--LQLEK 973
Query: 461 RGHDNWLAARTAERNLSDLRKENAHNKQKLTER---ELKFELLEKDPNALDVS 510
+ + E + D + ++KL E +L L E++ A +++
Sbjct: 974 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 74.3 bits (181), Expect = 4e-13
Identities = 96/399 (24%), Positives = 176/399 (44%), Gaps = 66/399 (16%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQK--EYEGYEVESSLEDASFEKAAAEEARSLEAT 131
+E++L A L+ L +E + +K + ++K E EG+ + ED E+AA +A +
Sbjct: 1095 KEEELQAALARLDDE---IAQKNNALKKIRELEGH-ISDLQEDLDSERAARNKAEKQKRD 1150
Query: 132 C-EKLSRSNSELED-----------------EILCLEKDLKEEKSKHSQQDELMADISKS 173
E+L +ELED E+ L+K L EE H Q + M K
Sbjct: 1151 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ--KH 1208
Query: 174 IQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV 233
Q++E+ ++ L+ Q AK K + E+ + L Q KQ + + +
Sbjct: 1209 AQAVEELTEQLE-QFKRAKANLDKNKQTLEKENADLAGELRVLGQA----KQEVEHKKKK 1263
Query: 234 WKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL 293
+ QV EL + E ++ ++ +N ++++TG L + +A L +D
Sbjct: 1264 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS---- 1319
Query: 294 ELKVNSQWENGANLDDPPKGALKKLIHAAKLNVS--LKSLEGERNHIIIQLSEVDKTKEE 351
++SQ ++ L KLNVS L+ LE ERN + QL E + K+
Sbjct: 1320 ---LSSQLQDTQELLQEET--------RQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQN 1368
Query: 352 LTEHIKNLQTQQASLQSENIYF-------ESENQKLQQKLKIMTEFYQENEMKLYRKLTV 404
L HI L Q + + + F E ++ Q++++ +T+ Y+E + Y KL
Sbjct: 1369 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKL-- 1425
Query: 405 EENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEE 443
E+ +R+++++ +L+ R+L +LE++
Sbjct: 1426 --------EKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Score = 63.9 bits (154), Expect = 5e-10
Identities = 99/453 (21%), Positives = 185/453 (40%), Gaps = 74/453 (16%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSL---EATCEKLSRSNSELE 143
E K K LE L+ + + S E E+ ++ +L E + L++ ++ E
Sbjct: 984 EAKIKKLEDEILVMDDQNN---KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1040
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEE 203
I LE LK+E+ + ++L + ++ L++QIAE K+ + K EE
Sbjct: 1041 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM--QLAKKEEE 1098
Query: 204 RRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKE 263
+A A+ +E +Q + K++ + E G +S+L + + ++ AE+ D
Sbjct: 1099 LQA-ALARLDDEIAQKNNALKKIRELE-----GHISDLQEDLDSERAARNKAEKQKRDLG 1152
Query: 264 NHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAK 323
++ L L EDT D + ++ ++ E + LKK +
Sbjct: 1153 EELEALKTEL-----------EDTLDSTATQQELRAKREQEVTV-------LKKALDEET 1194
Query: 324 LNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQK 383
+ + E + H + EELTE ++ + +A+L E EN L +
Sbjct: 1195 RSHEAQVQEMRQKHA--------QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1246
Query: 384 LKIMTEFYQENEMK----------LYRKLTVEENYRIEEEEKLSRVEEKISHATEELETY 433
L+++ + QE E K L K + E R E +K+ +++ ++ T L
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306
Query: 434 R----KLAKD---LEEELERTVHFYQKQV------------ISYEKRGHDNWL-----AA 469
KLAKD L +L+ T Q++ + E+ + L A
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 470 RTAERNLSDLRKENAHNKQKLTERELKFELLEK 502
+ ER++S L + + +K+KL + E LE+
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399
Score = 55.8 bits (133), Expect = 1e-07
Identities = 102/491 (20%), Positives = 197/491 (40%), Gaps = 89/491 (18%)
Query: 91 KLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE---KLSRSNSELEDEIL 147
+LL + I +Y + E E A AR+LE E +L R+N L+ E+
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM- 1520
Query: 148 CLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFK-------- 199
+DL K D+ K++ LE ++L++Q+ E K + +
Sbjct: 1521 ---EDLVSSKD----------DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1567
Query: 200 ------------MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV----WKGQVSELNK 243
+ R + +D NE + Q +QL + E E+ + ++ K
Sbjct: 1568 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL-QRQLHEYETELEDERKQRALAAAAK 1626
Query: 244 QKI--TFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD---------- 291
+K+ +D ++ A+ + +E IK L MKD LE+ D
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1686
Query: 292 ----NLELKVNSQWENGANLDDPPKGA-LKKLIHAAKLNVSL---KSLEGERNHIIIQLS 343
+LE + E+ A + K A L+K A +L SL +L+ E+ + +++
Sbjct: 1687 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746
Query: 344 EVDKTKEE--------------LTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
++++ EE T+ + L + A+ +S ES Q+L+++ K +
Sbjct: 1747 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1806
Query: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELER--- 446
E E + K ++ E K++++EE++ E + K K +++L+
Sbjct: 1807 KLHEMEGAVKSKF---KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILL 1863
Query: 447 TVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNA 506
V +K Y+++ + +R L + +E+ Q++ K L+++ +
Sbjct: 1864 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES----QRINANRRK---LQRELDE 1916
Query: 507 LDVSNTAFGRE 517
SN A GRE
Sbjct: 1917 ATESNEAMGRE 1927
Score = 43.1 bits (100), Expect = 0.001
Identities = 78/370 (21%), Positives = 141/370 (38%), Gaps = 37/370 (10%)
Query: 86 IEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELE-- 143
+E++ K + +K+ EG + L+ S K E + L ++ ELE
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 144 ----DEILCLEKDLKEEKSKHSQQD-----ELMADISKSIQSLEDESKSLKSQIAEAKII 194
DEI K+ E+K+K + D E +A ++ + + E + L ++A + +
Sbjct: 1672 RASRDEIFATAKE-NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA-SSLS 1729
Query: 195 CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVH 254
+ E+RR A L E + + + + Q +L+ + T +
Sbjct: 1730 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1789
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGA 314
E E K L L M + AV + + LE K+ +Q E + K A
Sbjct: 1790 NESARQQLERQNKELRSKLHEM--EGAVKSKFKSTIAALEAKI-AQLEEQVEQEAREKQA 1846
Query: 315 LKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTE-------HIKNLQTQQASLQ 367
K SLK + + I++Q+ + K E+ E +K L+ Q +
Sbjct: 1847 ATK---------SLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1897
Query: 368 SENIYFESENQKLQQKLKIMTEFYQE-----NEMKLYRKLTVEENYRIEEEEKLSRVEEK 422
E+ + +KLQ++L TE + N +K + E ++ RV E
Sbjct: 1898 EESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIEN 1957
Query: 423 ISHATEELET 432
+ EE +T
Sbjct: 1958 ADGSEEETDT 1967
Score = 37.4 bits (85), Expect = 0.054
Identities = 42/173 (24%), Positives = 73/173 (42%), Gaps = 12/173 (6%)
Query: 344 EVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENE---MKLYR 400
E+ KTKE + + + L+ ++ E LQ++L+ TE Y E E ++L
Sbjct: 867 ELQKTKERQ----QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAA 922
Query: 401 KLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEK 460
K E E E +L E++ E + + DLEE+LE QK + EK
Sbjct: 923 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK--LQLEK 980
Query: 461 RGHDNWLAARTAERNLSDLRKENAHNKQKLTER---ELKFELLEKDPNALDVS 510
+ + E + D + ++KL E +L L E++ A +++
Sbjct: 981 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 74.3 bits (181), Expect = 4e-13
Identities = 96/399 (24%), Positives = 176/399 (44%), Gaps = 66/399 (16%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQK--EYEGYEVESSLEDASFEKAAAEEARSLEAT 131
+E++L A L+ L +E + +K + ++K E EG+ + ED E+AA +A +
Sbjct: 1095 KEEELQAALARLDDE---IAQKNNALKKIRELEGH-ISDLQEDLDSERAARNKAEKQKRD 1150
Query: 132 C-EKLSRSNSELED-----------------EILCLEKDLKEEKSKHSQQDELMADISKS 173
E+L +ELED E+ L+K L EE H Q + M K
Sbjct: 1151 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ--KH 1208
Query: 174 IQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV 233
Q++E+ ++ L+ Q AK K + E+ + L Q KQ + + +
Sbjct: 1209 AQAVEELTEQLE-QFKRAKANLDKNKQTLEKENADLAGELRVLGQA----KQEVEHKKKK 1263
Query: 234 WKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL 293
+ QV EL + E ++ ++ +N ++++TG L + +A L +D
Sbjct: 1264 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS---- 1319
Query: 294 ELKVNSQWENGANLDDPPKGALKKLIHAAKLNVS--LKSLEGERNHIIIQLSEVDKTKEE 351
++SQ ++ L KLNVS L+ LE ERN + QL E + K+
Sbjct: 1320 ---LSSQLQDTQELLQEET--------RQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQN 1368
Query: 352 LTEHIKNLQTQQASLQSENIYF-------ESENQKLQQKLKIMTEFYQENEMKLYRKLTV 404
L HI L Q + + + F E ++ Q++++ +T+ Y+E + Y KL
Sbjct: 1369 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKL-- 1425
Query: 405 EENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEE 443
E+ +R+++++ +L+ R+L +LE++
Sbjct: 1426 --------EKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Score = 63.9 bits (154), Expect = 5e-10
Identities = 99/453 (21%), Positives = 185/453 (40%), Gaps = 74/453 (16%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSL---EATCEKLSRSNSELE 143
E K K LE L+ + + S E E+ ++ +L E + L++ ++ E
Sbjct: 984 EAKIKKLEDEILVMDDQNN---KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1040
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEE 203
I LE LK+E+ + ++L + ++ L++QIAE K+ + K EE
Sbjct: 1041 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM--QLAKKEEE 1098
Query: 204 RRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKE 263
+A A+ +E +Q + K++ + E G +S+L + + ++ AE+ D
Sbjct: 1099 LQA-ALARLDDEIAQKNNALKKIRELE-----GHISDLQEDLDSERAARNKAEKQKRDLG 1152
Query: 264 NHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAK 323
++ L L EDT D + ++ ++ E + LKK +
Sbjct: 1153 EELEALKTEL-----------EDTLDSTATQQELRAKREQEVTV-------LKKALDEET 1194
Query: 324 LNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQK 383
+ + E + H + EELTE ++ + +A+L E EN L +
Sbjct: 1195 RSHEAQVQEMRQKHA--------QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1246
Query: 384 LKIMTEFYQENEMK----------LYRKLTVEENYRIEEEEKLSRVEEKISHATEELETY 433
L+++ + QE E K L K + E R E +K+ +++ ++ T L
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306
Query: 434 R----KLAKD---LEEELERTVHFYQKQV------------ISYEKRGHDNWL-----AA 469
KLAKD L +L+ T Q++ + E+ + L A
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 470 RTAERNLSDLRKENAHNKQKLTERELKFELLEK 502
+ ER++S L + + +K+KL + E LE+
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399
Score = 59.7 bits (143), Expect = 1e-08
Identities = 106/507 (20%), Positives = 202/507 (39%), Gaps = 89/507 (17%)
Query: 91 KLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE---KLSRSNSELEDEIL 147
+LL + I +Y + E E A AR+LE E +L R+N L+ E+
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM- 1520
Query: 148 CLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFK-------- 199
+DL K D+ K++ LE ++L++Q+ E K + +
Sbjct: 1521 ---EDLVSSKD----------DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1567
Query: 200 ------------MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV----WKGQVSELNK 243
+ R + +D NE + Q +QL + E E+ + ++ K
Sbjct: 1568 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL-QRQLHEYETELEDERKQRALAAAAK 1626
Query: 244 QKI--TFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD---------- 291
+K+ +D ++ A+ + +E IK L MKD LE+ D
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1686
Query: 292 ----NLELKVNSQWENGANLDDPPKGA-LKKLIHAAKLNVSL---KSLEGERNHIIIQLS 343
+LE + E+ A + K A L+K A +L SL +L+ E+ + +++
Sbjct: 1687 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746
Query: 344 EVDKTKEE--------------LTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
++++ EE T+ + L + A+ +S ES Q+L+++ K +
Sbjct: 1747 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1806
Query: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELER--- 446
E E + K ++ E K++++EE++ E + K K +++L+
Sbjct: 1807 KLHEMEGAVKSKF---KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILL 1863
Query: 447 TVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNA 506
V +K Y+++ + +R L + +E+ Q++ K L+++ +
Sbjct: 1864 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES----QRINANRRK---LQRELDE 1916
Query: 507 LDVSNTAFGREHSPCSPSPLGRPSSET 533
SN A GRE + G P ET
Sbjct: 1917 ATESNEAMGREVNALKSKLRGPPPQET 1943
Score = 42.7 bits (99), Expect = 0.001
Identities = 69/322 (21%), Positives = 125/322 (38%), Gaps = 32/322 (9%)
Query: 86 IEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELE-- 143
+E++ K + +K+ EG + L+ S K E + L ++ ELE
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 144 ----DEILCLEKDLKEEKSKHSQQD-----ELMADISKSIQSLEDESKSLKSQIAEAKII 194
DEI K+ E+K+K + D E +A ++ + + E + L ++A + +
Sbjct: 1672 RASRDEIFATAKE-NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA-SSLS 1729
Query: 195 CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVH 254
+ E+RR A L E + + + + Q +L+ + T +
Sbjct: 1730 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1789
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGA 314
E E K L L M + AV + + LE K+ +Q E + K A
Sbjct: 1790 NESARQQLERQNKELRSKLHEM--EGAVKSKFKSTIAALEAKI-AQLEEQVEQEAREKQA 1846
Query: 315 LKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTE-------HIKNLQTQQASLQ 367
K SLK + + I++Q+ + K E+ E +K L+ Q +
Sbjct: 1847 ATK---------SLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1897
Query: 368 SENIYFESENQKLQQKLKIMTE 389
E+ + +KLQ++L TE
Sbjct: 1898 EESQRINANRRKLQRELDEATE 1919
Score = 37.4 bits (85), Expect = 0.054
Identities = 42/173 (24%), Positives = 73/173 (42%), Gaps = 12/173 (6%)
Query: 344 EVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENE---MKLYR 400
E+ KTKE + + + L+ ++ E LQ++L+ TE Y E E ++L
Sbjct: 867 ELQKTKERQ----QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAA 922
Query: 401 KLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEK 460
K E E E +L E++ E + + DLEE+LE QK + EK
Sbjct: 923 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK--LQLEK 980
Query: 461 RGHDNWLAARTAERNLSDLRKENAHNKQKLTER---ELKFELLEKDPNALDVS 510
+ + E + D + ++KL E +L L E++ A +++
Sbjct: 981 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 74.3 bits (181), Expect = 4e-13
Identities = 96/399 (24%), Positives = 176/399 (44%), Gaps = 66/399 (16%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQK--EYEGYEVESSLEDASFEKAAAEEARSLEAT 131
+E++L A L+ L +E + +K + ++K E EG+ + ED E+AA +A +
Sbjct: 1088 KEEELQAALARLDDE---IAQKNNALKKIRELEGH-ISDLQEDLDSERAARNKAEKQKRD 1143
Query: 132 C-EKLSRSNSELED-----------------EILCLEKDLKEEKSKHSQQDELMADISKS 173
E+L +ELED E+ L+K L EE H Q + M K
Sbjct: 1144 LGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ--KH 1201
Query: 174 IQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV 233
Q++E+ ++ L+ Q AK K + E+ + L Q KQ + + +
Sbjct: 1202 AQAVEELTEQLE-QFKRAKANLDKNKQTLEKENADLAGELRVLGQA----KQEVEHKKKK 1256
Query: 234 WKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL 293
+ QV EL + E ++ ++ +N ++++TG L + +A L +D
Sbjct: 1257 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS---- 1312
Query: 294 ELKVNSQWENGANLDDPPKGALKKLIHAAKLNVS--LKSLEGERNHIIIQLSEVDKTKEE 351
++SQ ++ L KLNVS L+ LE ERN + QL E + K+
Sbjct: 1313 ---LSSQLQDTQELLQEET--------RQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQN 1361
Query: 352 LTEHIKNLQTQQASLQSENIYF-------ESENQKLQQKLKIMTEFYQENEMKLYRKLTV 404
L HI L Q + + + F E ++ Q++++ +T+ Y+E + Y KL
Sbjct: 1362 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKL-- 1418
Query: 405 EENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEE 443
E+ +R+++++ +L+ R+L +LE++
Sbjct: 1419 --------EKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Score = 63.9 bits (154), Expect = 5e-10
Identities = 99/453 (21%), Positives = 185/453 (40%), Gaps = 74/453 (16%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSL---EATCEKLSRSNSELE 143
E K K LE L+ + + S E E+ ++ +L E + L++ ++ E
Sbjct: 977 EAKIKKLEDEILVMDDQNN---KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEE 203
I LE LK+E+ + ++L + ++ L++QIAE K+ + K EE
Sbjct: 1034 SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM--QLAKKEEE 1091
Query: 204 RRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKE 263
+A A+ +E +Q + K++ + E G +S+L + + ++ AE+ D
Sbjct: 1092 LQA-ALARLDDEIAQKNNALKKIRELE-----GHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 264 NHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAK 323
++ L L EDT D + ++ ++ E + LKK +
Sbjct: 1146 EELEALKTEL-----------EDTLDSTATQQELRAKREQEVTV-------LKKALDEET 1187
Query: 324 LNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQK 383
+ + E + H + EELTE ++ + +A+L E EN L +
Sbjct: 1188 RSHEAQVQEMRQKHA--------QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1239
Query: 384 LKIMTEFYQENEMK----------LYRKLTVEENYRIEEEEKLSRVEEKISHATEELETY 433
L+++ + QE E K L K + E R E +K+ +++ ++ T L
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299
Query: 434 R----KLAKD---LEEELERTVHFYQKQV------------ISYEKRGHDNWL-----AA 469
KLAKD L +L+ T Q++ + E+ + L A
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 470 RTAERNLSDLRKENAHNKQKLTERELKFELLEK 502
+ ER++S L + + +K+KL + E LE+
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392
Score = 59.7 bits (143), Expect = 1e-08
Identities = 106/507 (20%), Positives = 202/507 (39%), Gaps = 89/507 (17%)
Query: 91 KLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE---KLSRSNSELEDEIL 147
+LL + I +Y + E E A AR+LE E +L R+N L+ E+
Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM- 1513
Query: 148 CLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFK-------- 199
+DL K D+ K++ LE ++L++Q+ E K + +
Sbjct: 1514 ---EDLVSSKD----------DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
Query: 200 ------------MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV----WKGQVSELNK 243
+ R + +D NE + Q +QL + E E+ + ++ K
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL-QRQLHEYETELEDERKQRALAAAAK 1619
Query: 244 QKI--TFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD---------- 291
+K+ +D ++ A+ + +E IK L MKD LE+ D
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
Query: 292 ----NLELKVNSQWENGANLDDPPKGA-LKKLIHAAKLNVSL---KSLEGERNHIIIQLS 343
+LE + E+ A + K A L+K A +L SL +L+ E+ + +++
Sbjct: 1680 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739
Query: 344 EVDKTKEE--------------LTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTE 389
++++ EE T+ + L + A+ +S ES Q+L+++ K +
Sbjct: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
Query: 390 FYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELER--- 446
E E + K ++ E K++++EE++ E + K K +++L+
Sbjct: 1800 KLHEMEGAVKSKF---KSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILL 1856
Query: 447 TVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNA 506
V +K Y+++ + +R L + +E+ Q++ K L+++ +
Sbjct: 1857 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES----QRINANRRK---LQRELDE 1909
Query: 507 LDVSNTAFGREHSPCSPSPLGRPSSET 533
SN A GRE + G P ET
Sbjct: 1910 ATESNEAMGREVNALKSKLRGPPPQET 1936
Score = 42.7 bits (99), Expect = 0.001
Identities = 69/322 (21%), Positives = 125/322 (38%), Gaps = 32/322 (9%)
Query: 86 IEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELE-- 143
+E++ K + +K+ EG + L+ S K E + L ++ ELE
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 144 ----DEILCLEKDLKEEKSKHSQQD-----ELMADISKSIQSLEDESKSLKSQIAEAKII 194
DEI K+ E+K+K + D E +A ++ + + E + L ++A + +
Sbjct: 1665 RASRDEIFATAKE-NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA-SSLS 1722
Query: 195 CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVH 254
+ E+RR A L E + + + + Q +L+ + T +
Sbjct: 1723 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1782
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGA 314
E E K L L M + AV + + LE K+ +Q E + K A
Sbjct: 1783 NESARQQLERQNKELRSKLHEM--EGAVKSKFKSTIAALEAKI-AQLEEQVEQEAREKQA 1839
Query: 315 LKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTE-------HIKNLQTQQASLQ 367
K SLK + + I++Q+ + K E+ E +K L+ Q +
Sbjct: 1840 ATK---------SLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1890
Query: 368 SENIYFESENQKLQQKLKIMTE 389
E+ + +KLQ++L TE
Sbjct: 1891 EESQRINANRRKLQRELDEATE 1912
Score = 37.4 bits (85), Expect = 0.054
Identities = 42/173 (24%), Positives = 73/173 (42%), Gaps = 12/173 (6%)
Query: 344 EVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENE---MKLYR 400
E+ KTKE + + + L+ ++ E LQ++L+ TE Y E E ++L
Sbjct: 860 ELQKTKERQ----QKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAA 915
Query: 401 KLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEK 460
K E E E +L E++ E + + DLEE+LE QK + EK
Sbjct: 916 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK--LQLEK 973
Query: 461 RGHDNWLAARTAERNLSDLRKENAHNKQKLTER---ELKFELLEKDPNALDVS 510
+ + E + D + ++KL E +L L E++ A +++
Sbjct: 974 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 73.9 bits (180), Expect = 5e-13
Identities = 95/470 (20%), Positives = 196/470 (41%), Gaps = 64/470 (13%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARS-LEATCE 133
E K A L+ L ++ +L+ + + E L+ +K AE+A + L+ +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELT---------EKTGKLQQEEVQKKNAEQAATQLKVQLQ 491
Query: 134 KLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
+ R E++ I + + ++ + D+ + E+E +SL S++ + +
Sbjct: 492 EAERRWEEVQSYI----------RKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLV 541
Query: 194 ICKTFKMSEERRAIAIKDA----LNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFE 249
K E+R + + ++ +N+ LQ + + +Q E K Q+ + + Q
Sbjct: 542 S----KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN-EALKAQIQQFHSQIAAQT 596
Query: 250 DSKVHAEQ---VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGAN 306
+ V AE+ V+ +K+ IK L +D+ EE+ D N+ + ++ +
Sbjct: 597 SASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA 656
Query: 307 LDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASL 366
L + A +L E + + ++ ++ +E+L I N + L
Sbjct: 657 LANEQAAAAHEL-------------EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKIL 703
Query: 367 QSENIYFESENQKLQ---------QKLKIMTEFYQENEMKLYRKLTVEENYRIE---EEE 414
+N +SE QKLQ ++ M + QE + KL + E I+ +EE
Sbjct: 704 NDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEE 763
Query: 415 KLSRVEEKISHATEELETYRKLAKD------LEEELERTVHFYQKQVISYEKRGHDNWLA 468
+L+ + + S T+E++ + D L EEL++ +H ++ S E+ L
Sbjct: 764 ELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLK 823
Query: 469 ARTAERNLSDLRKENAHNKQKLTEREL-KFELLEKDPNALDVSNTAFGRE 517
E+ + DL++E K+++ +L K + L ++ N G+E
Sbjct: 824 VANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Score = 61.6 bits (148), Expect = 3e-09
Identities = 99/463 (21%), Positives = 204/463 (44%), Gaps = 63/463 (13%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT--C 132
+Q+L L L+E + K + K +Q + + ++ A ++ ++ A A+
Sbjct: 543 KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA 602
Query: 133 EKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAK 192
E+L + +E + +I E L E+ + + ++E + DI L+ E + L++ E
Sbjct: 603 EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQA 662
Query: 193 IICKTFKMSEERRAIAIKD----ALNENSQLQTSHK----QLFQQEAEVWKGQVSELNK- 243
++ + ++++ +KD L E Q + S+K ++ + + K +V +L
Sbjct: 663 --AAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTL 720
Query: 244 -QKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEED-----------TTDDD 291
+ +D E+ + +K+ +KT+ L Q A EE+ T +
Sbjct: 721 VSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ 780
Query: 292 NLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEE 351
+L+ K N Q + +++ LKK+IH + + +KS+E +++++ +KT ++
Sbjct: 781 DLKAKQNDQVSFASLVEE-----LKKVIH--EKDGKIKSVEELLEAELLKVANKEKTVQD 833
Query: 352 LTEHIKNLQTQQASLQSEN---IYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENY 408
L + IK L+ + ++Q E + S+ Q+LQ LK E Q N MK
Sbjct: 834 LKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEE--QMNTMKAV--------- 882
Query: 409 RIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLA 468
+EE+EK +L K +DL+EE E ++ + ++V + + + A
Sbjct: 883 -LEEKEK-------------DLANTGKWLQDLQEENE-SLKAHVQEVAQHNLKEASS--A 925
Query: 469 ARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDVSN 511
++ E + KEN + + +E + +L K DV +
Sbjct: 926 SQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
Score = 61.6 bits (148), Expect = 3e-09
Identities = 77/383 (20%), Positives = 171/383 (44%), Gaps = 38/383 (9%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEK--AAAEEARSLEAT 131
+++++ T L E+ +L K ++E + + + L A +K A A E +
Sbjct: 612 KDKQIKQTEDSLASERDRLTSK----EEELKDIQNMNFLLKAEVQKLQALANEQAAAAHE 667
Query: 132 CEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEA 191
EK+ +S +D+I LE+ L+ E S ++ +++ D +K+++S + ++L S+
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNK 727
Query: 192 KIICKTFKMSEER-RAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQ------ 244
++ + K +E+ + + L E +Q + K ++E + + S L K+
Sbjct: 728 DVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK---EEELNAIRTENSSLTKEVQDLKA 784
Query: 245 ----KITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
+++F ++V+++K+ IK++ L + A +E T D E+K +
Sbjct: 785 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVA-NKEKTVQDLKQEIKALKE 843
Query: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
L+ + ++ + +L LK E + N + L E +K + +++LQ
Sbjct: 844 EIGNVQLEKAQQLSITSKVQ--ELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
+ SL++ + Q LK + Q E+++ K E+E +L R+E
Sbjct: 902 EENESLKAH------VQEVAQHNLKEASSASQFEELEIVLK---------EKENELKRLE 946
Query: 421 EKISHATEELETYRKLAKDLEEE 443
+ +L + +L +D+++E
Sbjct: 947 AMLKERESDLSSKTQLLQDVQDE 969
Score = 55.1 bits (131), Expect = 2e-07
Identities = 82/368 (22%), Positives = 143/368 (38%), Gaps = 48/368 (13%)
Query: 143 EDEILCLEKDLKEEKS--KHSQQDELMADISKSIQSLEDESKSL---KSQIAEAKIICKT 197
EDE LC+ LKE+ + + + +++ I L+++ K L K A K CK
Sbjct: 298 EDEALCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQ 357
Query: 198 FK---MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVH 254
M+E+ R+ + + + +FQ + V E + ++ F+
Sbjct: 358 LTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHV---SYQETQQMQMKFQ----- 409
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLEL-KVNSQWENGANLDDPPKG 313
QV E I L +++D + + EL K+ + N G
Sbjct: 410 --QVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTG 467
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ----QASLQSE 369
L++ V K+ E + +QL E ++ EE+ +I+ + Q LQS+
Sbjct: 468 KLQQE------EVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSK 521
Query: 370 NIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEE 429
+ E+E Q L KL Q+ E +L +L E R+ +EE L + I E
Sbjct: 522 FVAKENEVQSLHSKLTDTLVSKQQLEQRL-MQLMESEQKRVNKEESLQMQVQDILEQNEA 580
Query: 430 LETY----------RKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAAR----TAERN 475
L+ + A L EEL + + KQ+ K+ D+ + R + E
Sbjct: 581 LKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQI----KQTEDSLASERDRLTSKEEE 636
Query: 476 LSDLRKEN 483
L D++ N
Sbjct: 637 LKDIQNMN 644
Score = 53.5 bits (127), Expect = 7e-07
Identities = 107/439 (24%), Positives = 190/439 (43%), Gaps = 45/439 (10%)
Query: 70 LYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLE 129
L G+E+++ T+ ++EEK K L K + + E+ A ++ A +
Sbjct: 868 LLKGKEEQMN-TMKAVLEEKEKDLANTG---KWLQDLQEENESLKAHVQEVAQHNLKEAS 923
Query: 130 ATC--EKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQ 187
+ E+L E E+E+ LE LKE +S S + +L+ D+ +DE+K KSQ
Sbjct: 924 SASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDV-------QDENKLFKSQ 976
Query: 188 IAEAK----IICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNK 243
I + K +F EE + I + E S L L + E + + ++L +
Sbjct: 977 IEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSL-KDAVEHQRKKNNDLRE 1034
Query: 244 QKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLE-EDTTDDDNLELKVNSQWE 302
+ ++ E++L DK N T + +A LE ++ ++ V S
Sbjct: 1035 KNWEAMEALASTEKMLQDKVNK----TSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLS 1090
Query: 303 NGANLDDPPKGALKKLIHAAKLNVSLKSL-----EGERNHIIIQLSEVDKTKEELTEHIK 357
G L K A K+ + + +K L E + H ++QL E +K K L E
Sbjct: 1091 YGEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQL-ECEKYKSVLAETEG 1148
Query: 358 NLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVE---ENYRIEEEE 414
LQ Q S++ E ++ + + + +K M + +E +L R + EN R E E
Sbjct: 1149 ILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREH 1208
Query: 415 ---KLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAART 471
+L + E + S E+ + L +L+++L+ + Y + V E+ N L A+
Sbjct: 1209 LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDS---YSEAVRQNEEL---NLLKAQL 1262
Query: 472 AERNLSDLRKENAHNKQKL 490
E L+ LR E + +QK+
Sbjct: 1263 NE-TLTKLRTEQ-NERQKV 1279
Score = 32.3 bits (72), Expect = 1.7
Identities = 31/143 (21%), Positives = 66/143 (46%), Gaps = 9/143 (6%)
Query: 99 IQKEYEGYEVESSL---EDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCLEKDLKE 155
++ E E E+E S E + E + L+ + + R N EL L + L +
Sbjct: 1209 LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTK 1268
Query: 156 EKSKHSQQDELMADISKSIQSLE-DESKSLKSQ-----IAEAKIICKTFKMSEERRAIAI 209
+++ +++ ++ D+ K+ QSLE +SK +K+ I + + +T +E ++++
Sbjct: 1269 LRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSL 1328
Query: 210 KDALNENSQLQTSHKQLFQQEAE 232
+ + QL + Q +E E
Sbjct: 1329 NQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 73.9 bits (180), Expect = 5e-13
Identities = 95/470 (20%), Positives = 196/470 (41%), Gaps = 64/470 (13%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARS-LEATCE 133
E K A L+ L ++ +L+ + + E L+ +K AE+A + L+ +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELT---------EKTGKLQQEEVQKKNAEQAATQLKVQLQ 491
Query: 134 KLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
+ R E++ I + + ++ + D+ + E+E +SL S++ + +
Sbjct: 492 EAERRWEEVQSYI----------RKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLV 541
Query: 194 ICKTFKMSEERRAIAIKDA----LNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFE 249
K E+R + + ++ +N+ LQ + + +Q E K Q+ + + Q
Sbjct: 542 S----KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN-EALKAQIQQFHSQIAAQT 596
Query: 250 DSKVHAEQ---VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGAN 306
+ V AE+ V+ +K+ IK L +D+ EE+ D N+ + ++ +
Sbjct: 597 SASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQA 656
Query: 307 LDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASL 366
L + A +L E + + ++ ++ +E+L I N + L
Sbjct: 657 LANEQAAAAHEL-------------EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKIL 703
Query: 367 QSENIYFESENQKLQ---------QKLKIMTEFYQENEMKLYRKLTVEENYRIE---EEE 414
+N +SE QKLQ ++ M + QE + KL + E I+ +EE
Sbjct: 704 NDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEE 763
Query: 415 KLSRVEEKISHATEELETYRKLAKD------LEEELERTVHFYQKQVISYEKRGHDNWLA 468
+L+ + + S T+E++ + D L EEL++ +H ++ S E+ L
Sbjct: 764 ELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLK 823
Query: 469 ARTAERNLSDLRKENAHNKQKLTEREL-KFELLEKDPNALDVSNTAFGRE 517
E+ + DL++E K+++ +L K + L ++ N G+E
Sbjct: 824 VANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Score = 61.6 bits (148), Expect = 3e-09
Identities = 99/463 (21%), Positives = 204/463 (44%), Gaps = 63/463 (13%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT--C 132
+Q+L L L+E + K + K +Q + + ++ A ++ ++ A A+
Sbjct: 543 KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA 602
Query: 133 EKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAK 192
E+L + +E + +I E L E+ + + ++E + DI L+ E + L++ E
Sbjct: 603 EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQA 662
Query: 193 IICKTFKMSEERRAIAIKD----ALNENSQLQTSHK----QLFQQEAEVWKGQVSELNK- 243
++ + ++++ +KD L E Q + S+K ++ + + K +V +L
Sbjct: 663 --AAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTL 720
Query: 244 -QKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEED-----------TTDDD 291
+ +D E+ + +K+ +KT+ L Q A EE+ T +
Sbjct: 721 VSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ 780
Query: 292 NLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEE 351
+L+ K N Q + +++ LKK+IH + + +KS+E +++++ +KT ++
Sbjct: 781 DLKAKQNDQVSFASLVEE-----LKKVIH--EKDGKIKSVEELLEAELLKVANKEKTVQD 833
Query: 352 LTEHIKNLQTQQASLQSEN---IYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENY 408
L + IK L+ + ++Q E + S+ Q+LQ LK E Q N MK
Sbjct: 834 LKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEE--QMNTMKAV--------- 882
Query: 409 RIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLA 468
+EE+EK +L K +DL+EE E ++ + ++V + + + A
Sbjct: 883 -LEEKEK-------------DLANTGKWLQDLQEENE-SLKAHVQEVAQHNLKEASS--A 925
Query: 469 ARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDVSN 511
++ E + KEN + + +E + +L K DV +
Sbjct: 926 SQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
Score = 61.6 bits (148), Expect = 3e-09
Identities = 77/383 (20%), Positives = 171/383 (44%), Gaps = 38/383 (9%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEK--AAAEEARSLEAT 131
+++++ T L E+ +L K ++E + + + L A +K A A E +
Sbjct: 612 KDKQIKQTEDSLASERDRLTSK----EEELKDIQNMNFLLKAEVQKLQALANEQAAAAHE 667
Query: 132 CEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEA 191
EK+ +S +D+I LE+ L+ E S ++ +++ D +K+++S + ++L S+
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNK 727
Query: 192 KIICKTFKMSEER-RAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQ------ 244
++ + K +E+ + + L E +Q + K ++E + + S L K+
Sbjct: 728 DVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK---EEELNAIRTENSSLTKEVQDLKA 784
Query: 245 ----KITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
+++F ++V+++K+ IK++ L + A +E T D E+K +
Sbjct: 785 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVA-NKEKTVQDLKQEIKALKE 843
Query: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
L+ + ++ + +L LK E + N + L E +K + +++LQ
Sbjct: 844 EIGNVQLEKAQQLSITSKVQ--ELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
+ SL++ + Q LK + Q E+++ K E+E +L R+E
Sbjct: 902 EENESLKAH------VQEVAQHNLKEASSASQFEELEIVLK---------EKENELKRLE 946
Query: 421 EKISHATEELETYRKLAKDLEEE 443
+ +L + +L +D+++E
Sbjct: 947 AMLKERESDLSSKTQLLQDVQDE 969
Score = 55.1 bits (131), Expect = 2e-07
Identities = 82/368 (22%), Positives = 143/368 (38%), Gaps = 48/368 (13%)
Query: 143 EDEILCLEKDLKEEKS--KHSQQDELMADISKSIQSLEDESKSL---KSQIAEAKIICKT 197
EDE LC+ LKE+ + + + +++ I L+++ K L K A K CK
Sbjct: 298 EDEALCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQ 357
Query: 198 FK---MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVH 254
M+E+ R+ + + + +FQ + V E + ++ F+
Sbjct: 358 LTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHV---SYQETQQMQMKFQ----- 409
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLEL-KVNSQWENGANLDDPPKG 313
QV E I L +++D + + EL K+ + N G
Sbjct: 410 --QVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTG 467
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ----QASLQSE 369
L++ V K+ E + +QL E ++ EE+ +I+ + Q LQS+
Sbjct: 468 KLQQE------EVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSK 521
Query: 370 NIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEE 429
+ E+E Q L KL Q+ E +L +L E R+ +EE L + I E
Sbjct: 522 FVAKENEVQSLHSKLTDTLVSKQQLEQRL-MQLMESEQKRVNKEESLQMQVQDILEQNEA 580
Query: 430 LETY----------RKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAAR----TAERN 475
L+ + A L EEL + + KQ+ K+ D+ + R + E
Sbjct: 581 LKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQI----KQTEDSLASERDRLTSKEEE 636
Query: 476 LSDLRKEN 483
L D++ N
Sbjct: 637 LKDIQNMN 644
Score = 53.5 bits (127), Expect = 7e-07
Identities = 107/439 (24%), Positives = 190/439 (43%), Gaps = 45/439 (10%)
Query: 70 LYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLE 129
L G+E+++ T+ ++EEK K L K + + E+ A ++ A +
Sbjct: 868 LLKGKEEQMN-TMKAVLEEKEKDLANTG---KWLQDLQEENESLKAHVQEVAQHNLKEAS 923
Query: 130 ATC--EKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQ 187
+ E+L E E+E+ LE LKE +S S + +L+ D+ +DE+K KSQ
Sbjct: 924 SASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDV-------QDENKLFKSQ 976
Query: 188 IAEAK----IICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNK 243
I + K +F EE + I + E S L L + E + + ++L +
Sbjct: 977 IEQLKQQNYQQASSFPPHEELLKV-ISEREKEISGLWNELDSL-KDAVEHQRKKNNDLRE 1034
Query: 244 QKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLE-EDTTDDDNLELKVNSQWE 302
+ ++ E++L DK N T + +A LE ++ ++ V S
Sbjct: 1035 KNWEAMEALASTEKMLQDKVNK----TSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLS 1090
Query: 303 NGANLDDPPKGALKKLIHAAKLNVSLKSL-----EGERNHIIIQLSEVDKTKEELTEHIK 357
G L K A K+ + + +K L E + H ++QL E +K K L E
Sbjct: 1091 YGEWLHGFEKKA-KECMAGTSGSEEVKVLEHKLKEADEMHTLLQL-ECEKYKSVLAETEG 1148
Query: 358 NLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVE---ENYRIEEEE 414
LQ Q S++ E ++ + + + +K M + +E +L R + EN R E E
Sbjct: 1149 ILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREH 1208
Query: 415 ---KLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAART 471
+L + E + S E+ + L +L+++L+ + Y + V E+ N L A+
Sbjct: 1209 LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDS---YSEAVRQNEEL---NLLKAQL 1262
Query: 472 AERNLSDLRKENAHNKQKL 490
E L+ LR E + +QK+
Sbjct: 1263 NE-TLTKLRTEQ-NERQKV 1279
Score = 32.3 bits (72), Expect = 1.7
Identities = 31/143 (21%), Positives = 66/143 (46%), Gaps = 9/143 (6%)
Query: 99 IQKEYEGYEVESSL---EDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCLEKDLKE 155
++ E E E+E S E + E + L+ + + R N EL L + L +
Sbjct: 1209 LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTK 1268
Query: 156 EKSKHSQQDELMADISKSIQSLE-DESKSLKSQ-----IAEAKIICKTFKMSEERRAIAI 209
+++ +++ ++ D+ K+ QSLE +SK +K+ I + + +T +E ++++
Sbjct: 1269 LRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSL 1328
Query: 210 KDALNENSQLQTSHKQLFQQEAE 232
+ + QL + Q +E E
Sbjct: 1329 NQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 73.6 bits (179), Expect = 7e-13
Identities = 94/436 (21%), Positives = 197/436 (45%), Gaps = 44/436 (10%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEI 146
EEK K L K ++ ++E + + LE+ + ++ + LE T KL +++L D+I
Sbjct: 1012 EEKSKSLAK---LKNKHEA--MITDLEERL--RREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 147 LCLEKDLKEEKSKHSQQDELMADISKSIQSLEDES----------KSLKSQIAEAKIICK 196
L+ + E K + ++++E ++ ++ +E+E+ + L+SQI+E + +
Sbjct: 1065 AELQAQIAELKMQLAKKEE---ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE 1121
Query: 197 TFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEA---EVWKGQVSELNKQKITFED-SK 252
+ + S + +D E L+T + A E+ + E+N K T E+ +K
Sbjct: 1122 SERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAK 1181
Query: 253 VHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPK 312
H Q+ ++ H + + ++ A LE+ NLE + L + K
Sbjct: 1182 THEAQIQEMRQKHSQAV-------EELAEQLEQTKRVKANLEKAKQTLENERGELANEVK 1234
Query: 313 GALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIY 372
L+ K +E + + ++ +E ++ + EL + + LQ + ++
Sbjct: 1235 VLLQG---KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQ 1291
Query: 373 FESENQKLQQKLKIMTEFYQENEMKLYRKLTVEEN-YRIEEEEKLSRVEEKISHATEELE 431
+S++ KL + + E++++ ++L EEN ++ KL +VE++ + E+LE
Sbjct: 1292 SDSKSSKLTKDFSAL-----ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE 1346
Query: 432 TYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLT 491
+ +LE+++ T+H QV +K+ D+ TAE L+K+ Q+
Sbjct: 1347 EEEEAKHNLEKQIA-TLH---AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHE 1402
Query: 492 ERELKFELLEKDPNAL 507
E+ ++ LEK L
Sbjct: 1403 EKVAAYDKLEKTKTRL 1418
Score = 67.0 bits (162), Expect = 6e-11
Identities = 95/430 (22%), Positives = 180/430 (41%), Gaps = 61/430 (14%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEI 146
E K K LE+ +I E + + E E AE +L EK S+S ++L+++
Sbjct: 970 EAKLKKLEEEQII---LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK-SKSLAKLKNKH 1025
Query: 147 LCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRA 206
+ DL+E + +Q + ++ K+ + LE +S L QIAE + KM ++
Sbjct: 1026 EAMITDLEERLRREEKQRQ---ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 207 IAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHI 266
++ AL + + + K + ++ + Q+SEL + + S+ AE+ D +
Sbjct: 1083 EELQAALARVEE-EAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141
Query: 267 KTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNV 326
+ L L EDT D + ++ S+ E N+ LKK +
Sbjct: 1142 EALKTEL-----------EDTLDSTAAQQELRSKREQEVNI-------LKKTLEEEAKTH 1183
Query: 327 SLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKI 386
+ E + H + EEL E ++ + +A+L+ E+E +L ++K+
Sbjct: 1184 EAQIQEMRQKH--------SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Query: 387 MTEFYQENEMK----------LYRKLTVEENYRIEEEEKLSRVEEKISHATEEL----ET 432
+ + ++E K L K E R E +K+++++ ++ + T L
Sbjct: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
Query: 433 YRKLAKD---LEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQK 489
KL KD LE +L+ T Q++ + L+ T + + D ++N+ +Q
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEE--------NRQKLSLSTKLKQVED--EKNSFREQL 1345
Query: 490 LTERELKFEL 499
E E K L
Sbjct: 1346 EEEEEAKHNL 1355
Score = 65.5 bits (158), Expect = 2e-10
Identities = 97/443 (21%), Positives = 183/443 (41%), Gaps = 50/443 (11%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASF--EKAAAE-EARSLEATCEKLSRSNSELE 143
+ C L +K QK+++ E A + E+ AE EAR E L+R+ E
Sbjct: 1434 QSACNLEKK----QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI---------- 193
++ LE+ K+ +++ D+ KS+ LE ++L+ Q+ E K
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Query: 194 ICKTFKMSEERRAIAIK-----DALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITF 248
+ K+ E A+K D + Q + KQL +Q E+ + ++ + KQ+
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREM-EAELEDERKQRSMA 1608
Query: 249 EDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLD 308
++ E L D E HI + + Q L+ D LD
Sbjct: 1609 VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR-------------ELD 1655
Query: 309 DPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQS 368
D + L A + LKS+E E + +L+ ++ K + + L + A+
Sbjct: 1656 DTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSG 1715
Query: 369 ENIYFESENQKLQQKLKIMTEFYQENE--MKLYRKLTVEENYRIEEEEKLSRVE----EK 422
+ E ++L+ ++ + E +E + +L + N +I++ +E +K
Sbjct: 1716 KGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQK 1775
Query: 423 ISHATEELETYRKLAKDLEEELERTVHF-YQKQVISYEKRGHDNWLAARTAERNLSDLRK 481
+A ++LE K K +E+E TV Y+ + + E + A+ E+ ++ ++
Sbjct: 1776 NENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNETKE 1829
Query: 482 ENAHNKQ-KLTERELKFELLEKD 503
A KQ + TE++LK LL+ D
Sbjct: 1830 RQAACKQVRRTEKKLKDVLLQVD 1852
Score = 60.8 bits (146), Expect = 5e-09
Identities = 95/444 (21%), Positives = 175/444 (39%), Gaps = 97/444 (21%)
Query: 60 WRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEK 119
WR F V+ L V R+++ ++ KE E +V EK
Sbjct: 828 WRLFTKVKPLLQVSRQEE-------------------EMMAKEEELVKVR--------EK 860
Query: 120 AAAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED 179
A E R E + S+L E L L++ L+ E ++ +EL A ++ Q LE+
Sbjct: 861 QLAAENRLTE-----METLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEE 915
Query: 180 ESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVS 239
L++++ E + C+ + +++ I++ L E + + S +Q Q E + ++
Sbjct: 916 ICHDLEARVEEEEERCQHLQAEKKKMQQNIQE-LEEQLEEEESARQKLQLEKVTTEAKLK 974
Query: 240 ELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNS 299
+L +++I ED + E+ I T +L EE+ +LK
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNL---------TEEEEKSKSLAKLKNKH 1025
Query: 300 QWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNL 359
+ A + D + ++ +L + + LEG+ +L++ I L
Sbjct: 1026 E----AMITDLEERLRREEKQRQELEKTRRKLEGD--------------STDLSDQIAEL 1067
Query: 360 QTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRV 419
Q Q A L+ + + ++LQ L + E + M L +K+ +
Sbjct: 1068 QAQIAELKMQ---LAKKEEELQAALARVEEEAAQKNMAL---------------KKIREL 1109
Query: 420 EEKISHATEELETYR-------KLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTA 472
E +IS E+LE+ R K +DL EELE K ++ L + A
Sbjct: 1110 ESQISELQEDLESERASRNKAEKQKRDLGEELEAL------------KTELEDTLDSTAA 1157
Query: 473 ERNLSDLRKENAHNKQKLTERELK 496
++ L R++ + +K E E K
Sbjct: 1158 QQELRSKREQEVNILKKTLEEEAK 1181
Score = 36.2 bits (82), Expect = 0.12
Identities = 21/108 (19%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEI 146
E K KL E ++ +Y+ + A E+ E + +A C+++ R+ +L+D +
Sbjct: 1789 ELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVL 1848
Query: 147 LCLEKDLKEEKSKHSQQDELMADISKSIQSLED-ESKSLKSQIAEAKI 193
L ++ + + + Q D+ + + + LE+ E ++ ++ + K+
Sbjct: 1849 LQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKL 1896
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 73.2 bits (178), Expect = 9e-13
Identities = 90/434 (20%), Positives = 189/434 (43%), Gaps = 36/434 (8%)
Query: 85 LIEEKCKLLEKFSLIQKEY-EGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELE 143
L ++ +L +K ++E+ E +V + + K + E+ + E+L +
Sbjct: 489 LARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIL 548
Query: 144 DEILCLEKDLKEEKSKHSQQD-ELMADISKSIQSLEDESKSLKSQI-AEAKIICKTFKMS 201
E +DL++E + + EL + + KS+Q +++SK L + AE K +
Sbjct: 549 TESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVM 608
Query: 202 EERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQK--ITFEDSKV----HA 255
E+ ++ ++ L T Q+ +Q+ + ++ E +Q+ +D ++ H
Sbjct: 609 VEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHI 668
Query: 256 EQV-------LNDKENHIKTLTGHLPMMKDQAAVLEEDTT----DDDNLELKVNSQWENG 304
E++ L+ K+ +++L+ L + LEE+ + D ++ ++ ++ +
Sbjct: 669 EEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQ 728
Query: 305 ANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ-- 362
N ++ K H + + K+L+ + N + + L E DK +E H++NL+
Sbjct: 729 KNHHQQQVDSIIKE-HEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIK 787
Query: 363 --QASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
+ LQ + + Q Q T+ Y+E +L +KL E RI ++++ VE
Sbjct: 788 RSEGELQQASAKLDVF-QSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVE 846
Query: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
+ EL+ ++ +DL ++LE+ +++V S + E L D
Sbjct: 847 AQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKS----------LTQVYESKLEDGN 896
Query: 481 KENAHNKQKLTERE 494
KE KQ L E+E
Sbjct: 897 KEQEQTKQILVEKE 910
Score = 63.2 bits (152), Expect = 9e-10
Identities = 102/445 (22%), Positives = 189/445 (42%), Gaps = 58/445 (13%)
Query: 89 KCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEA-TCEKLSRSNSELEDEIL 147
K KLL++ + ++KE E +E S ++ F E A++ A + +SR + +++I
Sbjct: 971 KKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIE 1030
Query: 148 CL----EKDLKE-----EKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
L ++L + EK + Q +EL +Q E E LK +I C+
Sbjct: 1031 SLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI--LLFGCEKE 1088
Query: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQV 258
+M++E + ++ + +++ L +QL Q+ A V N K H E++
Sbjct: 1089 EMNKEITWLK-EEGVKQDTTLNELQEQLKQKSAHV--------NSLAQDETKLKAHLEKL 1139
Query: 259 LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKL 318
D +K T + + + EED L K+ + D +LK
Sbjct: 1140 EVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKT--------TDEEFQSLKSS 1191
Query: 319 IHAAKLNVSLKSLEGER--NHIIIQLSEVDKTKEEL----TEHIKNLQTQQA-SLQSENI 371
+ ++ KSLE ++ + IQL K E L T + N+ + + ++ S
Sbjct: 1192 HEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRIS 1251
Query: 372 YFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELE 431
+ + K+++ L I T E E +L R+LT E+N + AT +LE
Sbjct: 1252 HCQHRTTKVKEALLIKTCTVSELEAQL-RQLTEEQN----------TLNISFQQATHQLE 1300
Query: 432 TYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHN----- 486
K ++ ++E V +K+ + +K G + AA E ++ L+KE + N
Sbjct: 1301 EKENQIKSMKADIESLV--TEKEAL--QKEGGNQQQAASEKESCITQLKKELSENINAVT 1356
Query: 487 --KQKLTERELKFELLEKDPNALDV 509
K++L E++++ L K L+V
Sbjct: 1357 LMKEELKEKKVEISSLSKQLTDLNV 1381
Score = 62.8 bits (151), Expect = 1e-09
Identities = 91/451 (20%), Positives = 200/451 (44%), Gaps = 60/451 (13%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE 133
REQK + + EE K L ++ + E + + EK + EE SL+ +
Sbjct: 402 REQKEKSERAAF-EELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQ---Q 457
Query: 134 KLSRSNSEL--------EDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLK 185
+LSR E+ E++I L+K ++E ++ Q+ ++K +Q+ E E + +
Sbjct: 458 ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQE------LTKKLQTREREFQE-Q 510
Query: 186 SQIAEAKIICKTFKMSEERR---AIAIKDA-LNENSQLQTSHKQL--FQQEAEVWKGQVS 239
++A K + K+S+E+ ++A+++ L + + L S +L QQEAE ++ ++
Sbjct: 511 MKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRIL 570
Query: 240 ELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQ-----AAVLEEDTTDDDNLE 294
EL E+ L + +N K L HL K++ ++E+ T+ ++L+
Sbjct: 571 ELESS----------LEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLK 620
Query: 295 LKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHI-----IIQLSEVDKTK 349
+ ++ W K + K + ++ + E E+ + II + +++
Sbjct: 621 HQQDALWTE--------KLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMN 672
Query: 350 EELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYR 409
E+ E + QT+ SL SE KL+++L ++ + + + +L K+ ++N+
Sbjct: 673 EKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHH 732
Query: 410 IEEEEKLSRVEEKISHATE-----ELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHD 464
++ + + + E TE ++ L K+ ++ L+ H + + + + +
Sbjct: 733 QQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKE--HQAHVENLEADIKRSE 790
Query: 465 NWLAARTAERNLSDLRKENAHNKQKLTEREL 495
L +A+ ++ + H + K E +L
Sbjct: 791 GELQQASAKLDVFQSYQSATHEQTKAYEEQL 821
Score = 62.4 bits (150), Expect = 2e-09
Identities = 88/383 (22%), Positives = 171/383 (44%), Gaps = 34/383 (8%)
Query: 136 SRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC 195
S S SE E I L K EEK + Q + D+S + +L E S Q+ +
Sbjct: 1386 SISLSEKEAAISSLRKQYDEEKCELLDQ---VQDLSFKVDTLSKEKISALEQVDDWSNKF 1442
Query: 196 KTFKMSEERRAIAIKDALNE-NSQLQTSHKQLFQQEAEV--WKGQVSELNKQ----KITF 248
+K + R ++ + E QL+ K+ ++++ ++ K ++ + NK+ K
Sbjct: 1443 SEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM 1502
Query: 249 EDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLD 308
ED K E+ ++ E +K+ T + ++D + + T + ++L +V + +++
Sbjct: 1503 EDDKSKMEKKESNLETELKSQTARIMELEDH---ITQKTIEIESLN-EVLKNYNQQKDIE 1558
Query: 309 DPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQL-SEVDKTKEELTEHIKNLQTQQASLQ 367
K ++KL H +L + E I+ L ++V K EL K L+ S++
Sbjct: 1559 H--KELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVK 1616
Query: 368 SENIYFESENQKLQQKLKIMTEFYQENEMKLYR-KLTVEENYRIEEEEKLSRVEEKISHA 426
S+ E E + L+ +L+ E+ KL K E+ +++ LS++EEK
Sbjct: 1617 SK----EEELKALEDRLE------SESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQY 1666
Query: 427 TEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHN 486
+ E++ +E ER VH ++++ S E + + R+A+ + +E A +
Sbjct: 1667 KKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADS 1726
Query: 487 K---QKLTERE---LKFELLEKD 503
+ QK E + L+ L EK+
Sbjct: 1727 QGCVQKTYEEKISVLQRNLTEKE 1749
Score = 53.5 bits (127), Expect = 7e-07
Identities = 98/474 (20%), Positives = 208/474 (43%), Gaps = 79/474 (16%)
Query: 80 ATLSGLIEEKCKL---LEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLS 136
A ++ L +++ KL LEK + ++ SL++ +F + E+ L+ E+
Sbjct: 1120 AHVNSLAQDETKLKAHLEKLEV--------DLNKSLKENTFLQ---EQLVELKMLAEEDK 1168
Query: 137 RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDES---KSLKSQIAEAKI 193
R SEL ++ +++ + KS H KS +SLED+S K L ++A
Sbjct: 1169 RKVSELTSKLKTTDEEFQSLKSSH----------EKSNKSLEDKSLEFKKLSEELAIQLD 1218
Query: 194 IC--KTFKMSEERRAIAIKDALNENSQL-----QTSHKQLFQQEAEVWK--------GQV 238
IC KT + E + I + ++ + + H+ +EA + K Q+
Sbjct: 1219 ICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQL 1278
Query: 239 SELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEED-------TTDDD 291
+L +++ T S A L +KEN IK++ + + + L+++ ++ +
Sbjct: 1279 RQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKE 1338
Query: 292 NLELKVNSQWENGANLDDPPKGALK-KLIHAAKLNVSLKSLE---------GERNHIIIQ 341
+ ++ + N K LK K + + L+ L L E+ I
Sbjct: 1339 SCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISS 1398
Query: 342 L-SEVDKTKEELTEHIKNLQTQQASLQSENI-----YFESENQKLQQKLKIMTEFYQE-- 393
L + D+ K EL + +++L + +L E I + N+ + K K + F Q
Sbjct: 1399 LRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQN 1458
Query: 394 --NEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFY 451
E+++ +L +E Y E++E+++ ++E++ + + + +D + ++E+
Sbjct: 1459 TVKELQIQLELKSKEAY--EKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNL 1516
Query: 452 QKQVISYEKR--GHDNWLAARTAE-RNLSDLRKENAHNKQKLTERELKFELLEK 502
+ ++ S R ++ + +T E +L+++ K +N+QK E + EL++K
Sbjct: 1517 ETELKSQTARIMELEDHITQKTIEIESLNEVLKN--YNQQKDIEHK---ELVQK 1565
Score = 49.3 bits (116), Expect = 1e-05
Identities = 107/532 (20%), Positives = 213/532 (40%), Gaps = 76/532 (14%)
Query: 64 RSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAE 123
+ + S++ EQ T S L E KL E+ E E + +E L+ S E + +E
Sbjct: 1653 KQLLSQMEEKEEQYKKGTESHLSELNTKLQER------EREVHILEEKLK--SVESSQSE 1704
Query: 124 EARSLEATCEKLSRSNSELEDEILCLEKDLKEEKS----KHSQQDELMADISKSIQSLED 179
+ + + E D C++K +E+ S +++++L+ + + +
Sbjct: 1705 TLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVS 1764
Query: 180 ESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVS 239
++ Q E I + + + I E + + + Q E G+ +
Sbjct: 1765 SHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNN 1824
Query: 240 ELNKQKI--TFED-SKVHAEQVLNDK--ENHIKTLTGHLPMMKDQAAV-LEEDTTDDDNL 293
KQ + F+D K E+ L + E IK L L K+ V +EE T+ + L
Sbjct: 1825 IQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKL 1884
Query: 294 ELKVNSQWENGAN--LDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEE 351
+ N L++ + K + KL L ++E + N + +L+ ++ K++
Sbjct: 1885 QALQQMDGRNKPTELLEENTEEKSKSHLVQPKL---LSNMEAQHNDLEFKLAGAEREKQK 1941
Query: 352 LTEHIKNLQTQQASLQSEN-----IYFESENQKLQQKLK----------------IMTEF 390
L + I LQ L+ E+ I + +Q+ ++K+K +M EF
Sbjct: 1942 LGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREF 2001
Query: 391 -----YQENEMKLYRKLTVEENYRIEEE------EKLSRVEEKISHATEELETYRKL--- 436
+E E+++ K T+ + +E E E+ +++ +KI+ ++L+ K
Sbjct: 2002 NTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEE 2061
Query: 437 ------------AKDLEEELERTVHFYQKQVISYEKRGHDN----WLAARTAERN--LSD 478
+DL+ +LE YQ+++ E G+DN L + A++ +SD
Sbjct: 2062 ILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISD 2121
Query: 479 LRKENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPS 530
+ + ++++ E + + EK+ A V G S G P+
Sbjct: 2122 SKLKEQEFREQIHNLEDRLKKYEKNVYATTVGTPYKGGNLYHTDVSLFGEPT 2173
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 72.8 bits (177), Expect = 1e-12
Identities = 109/564 (19%), Positives = 228/564 (40%), Gaps = 50/564 (8%)
Query: 64 RSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEY-----EGYEVESSLEDASFE 118
+ VR+ ++++ + LS EE + + +Q+E E + ++ LE+ +
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Query: 119 KAA-AEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSL 177
A ++ SLEA + +S S+ E + ++K L++ ++K Q+E + + + +IQ L
Sbjct: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
Query: 178 EDESKSLKSQI-----AEAKIICKTFKMSEERRAIAIKDALNENSQLQTSH--KQLFQQE 230
E L+ ++ +K + + EE R K QL+ + KQ +E
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
Query: 231 AEVWKGQVSELNKQ--KITFEDSK------VHAEQVLNDKENHIKTLTGHLPMMKDQAAV 282
+G+++ L+ Q + FE K + +L D + + L P ++ A +
Sbjct: 1629 KRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQL 1688
Query: 283 LEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQL 342
+ + V ++ ++D L L L+ E+N I +L
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748
Query: 343 SEVDKTKEELTEHIKNLQTQQA-------SLQSENIYFESENQKLQQKLKIMTEFYQENE 395
E + EL + K Q + LQ++ E Q+LQ+KL+ + +++
Sbjct: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL-----QSQ 1803
Query: 396 MKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQV 455
++ + V+++ +E K+ +E ++ +++ LA L+E +E+ +++
Sbjct: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRI 1863
Query: 456 ISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDVSNTAFG 515
+ + N + +R L D ++E +K E K LE D +L+ +N +
Sbjct: 1864 AAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQ 1919
Query: 516 REHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNE 575
+ + Q +ED + G S + L+ ++
Sbjct: 1920 AD-----------LKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGV 1968
Query: 576 RGEPSYDRLIDPHRAPSDTGSLSS 599
+ S ++ P +A SD GSL S
Sbjct: 1969 KSWLSKNK--GPSKAASDDGSLKS 1990
Score = 37.4 bits (85), Expect = 0.054
Identities = 41/207 (19%), Positives = 85/207 (41%), Gaps = 13/207 (6%)
Query: 323 KLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQ-------SENIYFES 375
+L L+ E ERN + + ++ ELT + + + S +E + E
Sbjct: 1265 QLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEK 1324
Query: 376 ENQKLQQKLKIMTEFYQENEMKLYRKLTV---EENYRIEEEEKLSRVEEKISHATEELET 432
E ++LQ + + + + EM++ + E N +++++ K A E++
Sbjct: 1325 EMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDF 1384
Query: 433 YRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
+K L++E E + Q+ E+R D + ++R L L+K+ +L +
Sbjct: 1385 TKKR---LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQD 1441
Query: 493 RELKFELLEKDPNALDVSNTAFGREHS 519
+L E + + L+ F E S
Sbjct: 1442 TKLHLEGQQVRNHELEKKQRRFDSELS 1468
Score = 33.1 bits (74), Expect = 1.0
Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 20/133 (15%)
Query: 378 QKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLA 437
++LQQ+ + E Q+N+ +L R+L + E + L ++++K T EL+
Sbjct: 1387 KRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ------ 1440
Query: 438 KDLEEELERTVHFYQKQVISYE----KRGHDNWLAARTAERNLSDLRKENAHNKQKLTER 493
+ +H +QV ++E +R D+ L+ E L++E ++ +
Sbjct: 1441 -------DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
Query: 494 E---LKFELLEKD 503
E LK +L EKD
Sbjct: 1494 EAFSLKQQLEEKD 1506
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 72.0 bits (175), Expect = 2e-12
Identities = 101/473 (21%), Positives = 202/473 (42%), Gaps = 62/473 (13%)
Query: 86 IEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA-EEARSLEATCEKLSRSNSELED 144
+E+K K + K L E + + E + EK EE +L+ C KL S + D
Sbjct: 311 LEDKIKDINK-KLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSD 369
Query: 145 EILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEER 204
+ E+ L + S E + + +++ E+E L S + + K+
Sbjct: 370 TMTEKERILAQSASV-----EEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRI 424
Query: 205 RAIAIKDAL--NENSQLQTSHKQLFQQEAEVWKGQV-------SELNKQKITFEDSKVHA 255
+ + +L E +LQ S +L E EV K SEL+ ++ E +
Sbjct: 425 EVLEKEKSLLSQEKEELQMSLLKL-NNEYEVIKSTATRDISLDSELHDLRLNLEAKEQEL 483
Query: 256 EQVLNDKENHIKTL----------TGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGA 305
Q +++KE I + T H+ ++KDQ L + + D++ K+
Sbjct: 484 NQSISEKETLIAEIEELDRQNQEATKHMILIKDQ---LSKQQNEGDSIISKLKQ------ 534
Query: 306 NLDDPPKGALKKLIHAA---KLNVSLKSLEGERNHII---IQLSEVDKTKEELTEHIKNL 359
+L+D KK +H K++++ K L+ ++ +I + L+++ TK++L + ++NL
Sbjct: 535 DLNDE-----KKRVHQLEDDKMDIT-KELDVQKEKLIQSEVALNDLHLTKQKLEDKVENL 588
Query: 360 QTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRI------EEE 413
Q Q N+ + EN +L++ ++ E +L + L + N E E
Sbjct: 589 VDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKERE 648
Query: 414 EKLSRVEEKISHATEELETYRKLAKDLEEELERTV-------HFYQKQVISYEKRGHDNW 466
++ +++ +S + E +K+A D++ E E+ V H ++ + + +
Sbjct: 649 AEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKN 708
Query: 467 LAARTAERNLSDLRKENAHNKQKLTERELKFE-LLEKDPNALDVSNTAFGREH 518
T + ++ E K++L E K+E +E+ NA +++ +A EH
Sbjct: 709 TIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEH 761
Score = 62.4 bits (150), Expect = 2e-09
Identities = 92/395 (23%), Positives = 175/395 (44%), Gaps = 42/395 (10%)
Query: 141 ELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSL-----KSQIAEAKIIC 195
+LED+ + + K+L +K K Q + + D+ + Q LED+ ++L KSQ + I
Sbjct: 545 QLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQK 604
Query: 196 KTFKMSEERRAIA---------IKDALNENSQLQTSHKQLFQQEAEV--WKGQVSEL--- 241
+ ++ E R + +LN++S L ++EAEV K +SEL
Sbjct: 605 ENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQL 664
Query: 242 --NKQKITFEDSKVHAEQVL--NDKENHIKT-LTGHLPMMKDQAAVLEEDTTDDDNLELK 296
N +K+ F+ + + VL D + ++ L G+ + ++ ++E T + E++
Sbjct: 665 NENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVE--TLKMEKGEIE 722
Query: 297 VNSQWENGANLDDPPK--GALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTE 354
W L++ K +++L +A LN S LE E H+I + D EL +
Sbjct: 723 AELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHE--HLIKLNQKKDMEIAELKK 780
Query: 355 HIKNLQTQQASLQ---SENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIE 411
+I+ + T + S ++ + + +L K +I E +E KL +L +
Sbjct: 781 NIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRK 840
Query: 412 EEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDN--WLAA 469
E +EEK L + ++ L+EELER + + + D+ LA+
Sbjct: 841 NEILRQTIEEK----DRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELAS 896
Query: 470 RTAERN-LSDLRKENAHNKQKLTE--RELKFELLE 501
++ N + + +E + QK+ E + K +LL+
Sbjct: 897 EVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQ 931
Score = 49.3 bits (116), Expect = 1e-05
Identities = 69/364 (18%), Positives = 157/364 (43%), Gaps = 64/364 (17%)
Query: 65 SVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEE 124
+ ++L++ +++++ + + + K +L E+ IQ + E+ ++ + E + +
Sbjct: 952 ATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKH 1011
Query: 125 ARSLEATCEKLSRSNSELEDEILCL-EKDLKEEKSKHSQQDELMADISKSIQSLEDESKS 183
S +A E+L + E E EI L EK++ K + + +++ IQ + E ++
Sbjct: 1012 DLS-KAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQA 1070
Query: 184 LKSQIAEAKII---------CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQ----QE 230
L ++I+ + + M E+ + + ENS L+T + ++ +E
Sbjct: 1071 LHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKE 1130
Query: 231 AEVWKGQVSELNKQKIT---------FEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAA 281
A + K Q + NK+ T F ++ + +++ +K+ I L+ + A
Sbjct: 1131 AALIKLQ--DENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTL---LA 1185
Query: 282 VLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQ 341
VL+ +T ++ G N + + L ER+ + Q
Sbjct: 1186 VLQTSSTGNE----------AGGVNSNQ------------------FEELLQERDKLKQQ 1217
Query: 342 LSEVDKTKEELTEHIKNLQTQQASLQSENIYFESE-------NQKLQQKLKIMTEFYQEN 394
+ ++++ K+++ ++N+Q + A LQ E +++ N KLQ + + Y++N
Sbjct: 1218 VKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQN 1277
Query: 395 EMKL 398
E KL
Sbjct: 1278 ETKL 1281
Score = 48.1 bits (113), Expect = 3e-05
Identities = 105/500 (21%), Positives = 201/500 (40%), Gaps = 80/500 (16%)
Query: 59 LWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFE 118
L V + L R +++ A + L E +L + + +++++E E++ + S+
Sbjct: 38 LMEGTEEVEAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYR 97
Query: 119 KAAAEEARSLEATCEKLSRSNSELEDEILCLEK----------------------DLKEE 156
++ E L L+D++L L+ +
Sbjct: 98 NQLQQK----EVEISHLKARQIALQDQLLKLQSAAQSVPSGAGVPATTASSSFAYGISHH 153
Query: 157 KSKHSQQDELMADISKS---IQSLEDESKSLKSQIAEAKIICKTFKM-----SEERRAIA 208
S D DI S I L +E L+S++ + I +T K S++
Sbjct: 154 PSAFHDDDMDFGDIISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICK 213
Query: 209 IKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKT 268
+++ + E Q ++ Q E V + ++QK+T E S+ H E+ L+D E I+
Sbjct: 214 LQNIIKELKQNRSQEIDDHQHEMSV----LQNAHQQKLT-EISRRHREE-LSDYEERIEE 267
Query: 269 LTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAK-LNVS 327
L L + + V+E D + E++ Q ++ K +++L K +N
Sbjct: 268 LENLL--QQGGSGVIETDLSKI--YEMQKTIQVLQIEKVESTKK--MEQLEDKIKDINKK 321
Query: 328 LKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIM 387
L S E +R+ + + +++ K ++ E +NL+ E KLQ
Sbjct: 322 LSSAENDRDILRREQEQLNVEKRQIMEECENLKL--------------ECSKLQPSAVKQ 367
Query: 388 TEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKD-LEEELER 446
++ E E L + +VEE +R+ ++ LS E +I + L LA+D L+ ++
Sbjct: 368 SDTMTEKERILAQSASVEEVFRL--QQALSDAENEIMRLS-SLNQDNSLAEDNLKLKMRI 424
Query: 447 TVHFYQKQVISYEKR---------GHDNWLAARTAERNLS------DLRKENAHNKQKLT 491
V +K ++S EK ++ + TA R++S DLR +Q+L
Sbjct: 425 EVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELN 484
Query: 492 ERELKFELLEKDPNALDVSN 511
+ + E L + LD N
Sbjct: 485 QSISEKETLIAEIEELDRQN 504
Score = 42.0 bits (97), Expect = 0.002
Identities = 75/369 (20%), Positives = 147/369 (39%), Gaps = 61/369 (16%)
Query: 92 LLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDEILCLEK 151
L E L+Q+E E E+ SL++ +AT L +N L D I +
Sbjct: 1338 LSESSELLQQELE--ELRKSLQEK-------------DATIRTLQENNHRLSDSIAATSE 1382
Query: 152 DLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKD 211
E+ +H Q D I+ L+++ L+ + E ++ K A D
Sbjct: 1383 ---LERKEHEQTDS-------EIKQLKEKQDVLQKLLKEKDLLIK-----------AKSD 1421
Query: 212 AL---NENSQLQTSHKQLFQQEAEVWKGQVS--ELNKQKITFEDSKVHAEQVLNDKENHI 266
L NEN + + +L +Q K ++ E++ K+ E+ K+ + KE
Sbjct: 1422 QLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKI--VETYRGKETEY 1479
Query: 267 KTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAK-LN 325
+ L MK + +L E + +++ K + + + G L +L++A K +
Sbjct: 1480 QALQE--TNMKF-SMMLREKEFECHSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQ 1536
Query: 326 VSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLK 385
+ ER+ +++ L K Q + +LQ+E + + Q+L+
Sbjct: 1537 EKTVVFQQERDQVMLAL--------------KQKQMENTALQNEVQRLRDKEFRSNQELE 1582
Query: 386 IMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELE 445
+ E+E R+ E+ + +K++ +EEK+ ++ +E A E L+
Sbjct: 1583 RLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQ 1642
Query: 446 RTVHFYQKQ 454
++ KQ
Sbjct: 1643 EQLNVVSKQ 1651
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 72.0 bits (175), Expect = 2e-12
Identities = 94/476 (19%), Positives = 200/476 (42%), Gaps = 37/476 (7%)
Query: 64 RSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEY-----EGYEVESSLEDASFE 118
+ VR+ ++++ + LS EE + + +Q+E E + ++ LE+ +
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Query: 119 KAA-AEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSL 177
A ++ SLEA + +S S+ E + ++K L++ ++K Q+E + + + +IQ L
Sbjct: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
Query: 178 EDESKSLKSQI-----AEAKIICKTFKMSEERRAIAIKDALNENSQLQTSH--KQLFQQE 230
E L+ ++ +K + + EE R K QL+ + KQ +E
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
Query: 231 AEVWKGQVSELNKQ--KITFEDSK------VHAEQVLNDKENHIKTLTGHLPMMKDQAAV 282
+G+++ L+ Q + FE K + +L D + + L P ++ A +
Sbjct: 1629 KRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQL 1688
Query: 283 LEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQL 342
+ + V ++ ++D L L L+ E+N I +L
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748
Query: 343 SEVDKTKEELTEHIKNLQTQQA-------SLQSENIYFESENQKLQQKLKIMTEFYQENE 395
E + EL + K Q + LQ++ E Q+LQ+KL+ + +++
Sbjct: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL-----QSQ 1803
Query: 396 MKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQV 455
++ + V+++ +E K+ +E ++ +++ LA L+E +E+ +++
Sbjct: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRI 1863
Query: 456 ISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDVSN 511
+ + N + +R L D ++E +K E K LE D +L+ +N
Sbjct: 1864 AAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAAN 1915
Score = 44.7 bits (104), Expect = 3e-04
Identities = 78/392 (19%), Positives = 157/392 (40%), Gaps = 59/392 (15%)
Query: 100 QKEYEGYEVESSLEDASFEKAAAEEAR---SLEATCEKLSRSNSELEDEILCLEKDLKEE 156
QK+ + EV+ E +K E+ L ++++R + E E L KDLK
Sbjct: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKR---LRKDLKRT 1661
Query: 157 KSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC-------KTFKMSEERRAIAI 209
K+ + +LM D K+ + E LK+Q+ E++ C K ++ E + I
Sbjct: 1662 KALLADA-QLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQI 1720
Query: 210 KDALNENSQLQTSHKQLFQQEAEVW-----------------KGQVSELNKQKITFEDSK 252
D + L+ +L +++ E+ K V++ ++ D +
Sbjct: 1721 DDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQ 1780
Query: 253 VHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL--------ELKVNSQWENG 304
E+ +K+ L L ++ Q LE+ D + EL+ ++E
Sbjct: 1781 AQLEEANKEKQE----LQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT 1836
Query: 305 A-----NLDDPPKGALKKLIHAAKLNVSLKSLEGERN-HIIIQLSEVDKTKEELTEHIKN 358
+L K ++KL ++ ++ E E+N + QL + + EL
Sbjct: 1837 QVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1896
Query: 359 LQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSR 418
++ L+ + E+ NQ LQ LK+ + + + + ++ +EN E+ ++
Sbjct: 1897 ASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDEN-----EDLINS 1951
Query: 419 VEEKISHATEELETYRKLA--KDLEEELERTV 448
+++ + T+ + KL D++ ELE V
Sbjct: 1952 LQDMV---TKYQKRKNKLEGDSDVDSELEDRV 1980
Score = 37.4 bits (85), Expect = 0.054
Identities = 41/207 (19%), Positives = 85/207 (41%), Gaps = 13/207 (6%)
Query: 323 KLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQ-------SENIYFES 375
+L L+ E ERN + + ++ ELT + + + S +E + E
Sbjct: 1265 QLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEK 1324
Query: 376 ENQKLQQKLKIMTEFYQENEMKLYRKLTV---EENYRIEEEEKLSRVEEKISHATEELET 432
E ++LQ + + + + EM++ + E N +++++ K A E++
Sbjct: 1325 EMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDF 1384
Query: 433 YRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
+K L++E E + Q+ E+R D + ++R L L+K+ +L +
Sbjct: 1385 TKKR---LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQD 1441
Query: 493 RELKFELLEKDPNALDVSNTAFGREHS 519
+L E + + L+ F E S
Sbjct: 1442 TKLHLEGQQVRNHELEKKQRRFDSELS 1468
Score = 33.1 bits (74), Expect = 1.0
Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 20/133 (15%)
Query: 378 QKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLA 437
++LQQ+ + E Q+N+ +L R+L + E + L ++++K T EL+
Sbjct: 1387 KRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ------ 1440
Query: 438 KDLEEELERTVHFYQKQVISYE----KRGHDNWLAARTAERNLSDLRKENAHNKQKLTER 493
+ +H +QV ++E +R D+ L+ E L++E ++ +
Sbjct: 1441 -------DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
Query: 494 E---LKFELLEKD 503
E LK +L EKD
Sbjct: 1494 EAFSLKQQLEEKD 1506
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 70.9 bits (172), Expect = 4e-12
Identities = 102/494 (20%), Positives = 204/494 (41%), Gaps = 43/494 (8%)
Query: 43 LVVCAAVIGFFVVLLFLW-RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQK 101
LV+ + F V + W + + ++ L +K AT+ + LEK +K
Sbjct: 814 LVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRK 873
Query: 102 EYEGYEVESSLEDASFE---KAAAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKS 158
E E V E + +A + E C++L ++ +LE ++ KE
Sbjct: 874 ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKV-------KEMNE 926
Query: 159 KHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC------------KTFKMSEERRA 206
+ ++E+ A+++ + LEDE LK I + ++ K ++EE
Sbjct: 927 RLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 986
Query: 207 I--AIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFED-------SKVHAEQ 257
+ I E LQ +H+Q + +V + +V+ L+K K+ E S ++
Sbjct: 987 LDEIIAKLTKEKKALQEAHQQAL-DDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKK 1045
Query: 258 VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTD-DDNLELKVNSQWENGANLDDPPKGALK 316
V D E + L G L + ++ LE D ++ L+ K + + ++D AL+
Sbjct: 1046 VRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQ 1105
Query: 317 KLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ------QASLQSE- 369
+ ++ LE E ++V+K + +L+ ++ + + S+Q E
Sbjct: 1106 LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEM 1165
Query: 370 NIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEE 429
N E+E QK+++ L+ T ++ L +K E+ + L RV++K+ E
Sbjct: 1166 NKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSE 1225
Query: 430 LETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQK 489
+ E++ + +K + E + ++ + A+R+L+D + A K +
Sbjct: 1226 FKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRA--KLQ 1283
Query: 490 LTERELKFELLEKD 503
EL +L EK+
Sbjct: 1284 TENGELARQLEEKE 1297
Score = 69.7 bits (169), Expect = 1e-11
Identities = 102/456 (22%), Positives = 191/456 (41%), Gaps = 62/456 (13%)
Query: 66 VRSRLYVGR---EQKLGATLSGLIEEKCKLLE---KFSLIQKEYEGYEVESSLEDASFEK 119
VR +L V + + L + L E+ K+L +F+ I+ E E E E ++
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1590
Query: 120 AAAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED 179
SL+ + + +RS +E+ +E DL E + + S + + A+ K ++SL+
Sbjct: 1591 NHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1650
Query: 180 ESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVS 239
K + Q+ +A + D L EN + L Q E E + V
Sbjct: 1651 LLKDTQIQLDDA---------------VRANDDLKENIAIVERRNNLLQAELEELRAVVE 1695
Query: 240 ELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNS 299
+ E S+ AEQ L + ++ L + +Q +E D T L+ +V
Sbjct: 1696 QT-------ERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ---LQSEVEE 1745
Query: 300 QWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNL 359
+ N ++ K K + AA + LK + H+ ++ K+ + + IK+L
Sbjct: 1746 AVQECRNAEEKAK---KAITDAAMMAEELKKEQDTSAHL-------ERMKKNMEQTIKDL 1795
Query: 360 QTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRV 419
Q + ++E I + ++LQ+ + E E E++ +K E + + E+ R+
Sbjct: 1796 QHRLD--EAEQIALKGGKKQLQKLEARVREL--EGELEAEQKRNAESVKGMRKSER--RI 1849
Query: 420 EEKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDL 479
+E +++ TEE + +DL ++L+ V Y++Q E++ A NLS
Sbjct: 1850 KE-LTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQ----------ANTNLSKF 1898
Query: 480 RKENAHNKQKLTERELKFELLEKDPNALDVSNTAFG 515
RK + +L E E + ++ E N L + G
Sbjct: 1899 RKV----QHELDEAEERADIAESQVNKLRAKSRDIG 1930
Score = 58.5 bits (140), Expect = 2e-08
Identities = 100/482 (20%), Positives = 189/482 (39%), Gaps = 101/482 (20%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE 133
R ++ G S IE K +F ++++ E ++ A+ K A+ L +
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 134 KLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
L R +LE E + +L + S Q + A++ K ++LED++ + ++ EA+
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 194 ICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKV 253
++ D + ++LQT + +L +Q E + +S+L + K+++
Sbjct: 1271 --------------SLNDFTTQRAKLQTENGELARQLEEK-EALISQLTRGKLSYTQQME 1315
Query: 254 HAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLEL-------KVNS---QW-- 301
++ L ++ L L + +L E ++ + K NS QW
Sbjct: 1316 DLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1375
Query: 302 -------ENGANLDDPPKGALKKLIHAAK----LNVSLKSLEGERNHIIIQLSEV----- 345
+ L++ K ++L A + +N SLE ++ + ++ ++
Sbjct: 1376 KYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1435
Query: 346 ---------DKTK--------------EELTEHIKNLQTQQASLQSE-----NIYFES-- 375
DK + EE +++ Q + SL +E N Y ES
Sbjct: 1436 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1495
Query: 376 -------ENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEE------- 421
EN+ LQ+++ +TE E ++ V + +E+ E S +EE
Sbjct: 1496 HLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEH 1555
Query: 422 ---KISHATEEL-----ETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAE 473
KI A E E RKLA + +EE+E+ +Q+ V S + L A T
Sbjct: 1556 EEGKILRAQLEFNQIKAEIERKLA-EKDEEMEQAKRNHQRVVDSLQTS-----LDAETRS 1609
Query: 474 RN 475
RN
Sbjct: 1610 RN 1611
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 70.5 bits (171), Expect = 6e-12
Identities = 108/566 (19%), Positives = 226/566 (39%), Gaps = 84/566 (14%)
Query: 59 LWRSFRSVRSRLYVGREQ--KLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDAS 116
+WR +R + REQ K+ L E++ +L E+ ++++ + E E +++
Sbjct: 257 MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ- 315
Query: 117 FEKAAAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQS 176
E+ E+ + EK+ R L ++ EK ++E++ K Q+E M + + ++
Sbjct: 316 -EEKMWEQEEKMREQEEKMWRQEERLWEQ----EKQMREQEQKMRDQEERMWEQDERLRE 370
Query: 177 LEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQ-QEAEVWK 235
E+ + + + + KM EE R + + E + ++ Q QE +W+
Sbjct: 371 KEERMREQEKMWEQEE------KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 424
Query: 236 GQVSELNKQKITFEDSKVHAEQVLNDKENHI----------KTLTGHLPMMKDQAAVLE- 284
+ E +Q++ + K+ ++ + ++E I + + G M Q + E
Sbjct: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Query: 285 EDTTDDDNLELKVNSQ---------WENGANL---DDPPKGALKKLIHAAKLNVSLKSLE 332
ED + +++ Q WE L ++ + K K+ K+ E
Sbjct: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE 544
Query: 333 GERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKL---QQKLKIMTE 389
E+ E + +E + E K ++ ++ ++ + + + +K+ ++K+ E
Sbjct: 545 QEKK--TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Query: 390 FYQENEMKLYR------------KLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLA 437
QE E K++ K+ +E E+EEK+ EEK+ E++ +
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
Query: 438 KDLEEEL---ERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERE 494
++ EE++ E + ++++ E++ + R E + ++ ++K+ +E
Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE 722
Query: 495 LKFELLEKDPNALDVSNTAFGR--EH-----SPCSPSPLGRPSSETRAFPSPQTLLEDPL 547
E+ EK+ D R EH PC P P +L +
Sbjct: 723 ---EMREKEERIRDQKEKMQERLPEHEERCSEPCLP---------------PSKVLCNMS 764
Query: 548 RLSPVLPGGGGRGPSSP-GNPLDHQI 572
V P GG G SP NP +I
Sbjct: 765 HTGSVEPAGGEAGEGSPQDNPTAQEI 790
Score = 60.1 bits (144), Expect = 8e-09
Identities = 87/435 (20%), Positives = 186/435 (42%), Gaps = 35/435 (8%)
Query: 86 IEEKCKLLE-KFSLIQKEYEGYEVESSLEDASF------EKAAAEEARSLEATCEKLSRS 138
++EK +L E + S IQ + E++ LE A F EE E + +
Sbjct: 192 LQEKLRLAESEKSEIQLNVK--ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
Query: 139 NSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
+ E+++ E+ L+E++ K +Q+E M K ++ E E + + ++ E K
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ----KKL 305
Query: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVW--KGQVSELNKQKITFEDSKVHAE 256
+ EE+ + + +++ +++++QE +W + Q+ E ++ E+ +
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Query: 257 QVLNDKENHIK---TLTGHLPMMKDQAAVLE------EDTTDDDNLELKVNSQWENGANL 307
+ L +KE ++ + M+++ + E E+ E K+ Q EN
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 308 DDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQASLQ 367
++ + KL K E E I + E + +EE+ K + Q+ +
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEK--IWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 368 SENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHAT 427
E+ +E E + Q+ K+ + QE M + E+ R+ E++K+ + EEK+
Sbjct: 484 QEDQMWEQEEKMRDQEQKM---WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 428 EELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNK 487
+ E +K D EE++ ++++ EK+ + R E + + ++ +
Sbjct: 541 KTQEQEKK-TWDQEEKMRE-----EERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
Query: 488 QKLTERELKFELLEK 502
+K+ E+E K + E+
Sbjct: 595 EKMWEQEEKMQEQEE 609
Score = 44.7 bits (104), Expect = 3e-04
Identities = 62/285 (21%), Positives = 109/285 (38%), Gaps = 43/285 (15%)
Query: 223 HKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAV 282
H++ ++E E + L QK E + +++ E+ G+L KD A
Sbjct: 79 HQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFED------GNLGESKDLAGR 132
Query: 283 LEEDTTDDDNLE--LKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIII 340
L L+ L S W K + ++ L ER+ + +
Sbjct: 133 LHHSWHFAGELQRALSAVSTWHK-------------------KADRYIEELTKERDALSL 173
Query: 341 QLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKL---KIMTEFYQENEMK 397
+L T EEL + LQ + +SE + ++L++KL K + Q N
Sbjct: 174 ELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTN--T 231
Query: 398 LYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERTVHFYQKQVIS 457
L ++ +E E+E+K+ + EEK+ E L ++ EE++ R
Sbjct: 232 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR----------- 280
Query: 458 YEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEK 502
EKR + R E+ L + +K +Q + E +E EK
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEK 325
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,975,545
Number of Sequences: 37866
Number of extensions: 2244970
Number of successful extensions: 19786
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 295
Number of HSP's successfully gapped in prelim test: 1445
Number of HSP's that attempted gapping in prelim test: 10831
Number of HSP's gapped (non-prelim): 6180
length of query: 777
length of database: 18,247,518
effective HSP length: 110
effective length of query: 667
effective length of database: 14,082,258
effective search space: 9392866086
effective search space used: 9392866086
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.