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Search of human proteins with 223972648
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
(513 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 1019 0.0
gi|170932494 syntaxin 7 [Homo sapiens] 137 3e-32
gi|28933465 syntaxin 12 [Homo sapiens] 135 1e-31
gi|37537558 nuclear apoptosis inducing factor 1 [Homo sapiens] 68 2e-11
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens] 61 2e-09
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens] 58 2e-08
gi|60460889 Myb protein P42POP [Homo sapiens] 55 2e-07
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 53 8e-07
gi|4759184 syntaxin 3 [Homo sapiens] 53 8e-07
gi|47778943 syntaxin 16 isoform a [Homo sapiens] 52 1e-06
gi|198041692 syntaxin 16 isoform d [Homo sapiens] 52 1e-06
gi|198041688 syntaxin 16 isoform c [Homo sapiens] 52 1e-06
gi|34447229 syntaxin 16 isoform b [Homo sapiens] 52 1e-06
gi|58761537 hypothetical protein LOC84437 [Homo sapiens] 52 1e-06
gi|16418379 syntaxin 1B [Homo sapiens] 51 3e-06
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 50 5e-06
gi|20149560 syntaxin 4 [Homo sapiens] 49 1e-05
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 49 1e-05
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 49 1e-05
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 47 4e-05
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 47 4e-05
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 47 4e-05
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 45 2e-04
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 45 2e-04
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 44 3e-04
gi|117956403 rabaptin, RAB GTPase binding effector protein 2 [Ho... 44 3e-04
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 44 4e-04
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 44 5e-04
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 43 8e-04
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 42 0.001
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 1019 bits (2636), Expect = 0.0
Identities = 513/513 (100%), Positives = 513/513 (100%)
Query: 1 MSYGSIARGGGLGSRGPFGGPSRQGCQPLECARCWTEYGIRHFPCPSPESKLQNRCVGKD 60
MSYGSIARGGGLGSRGPFGGPSRQGCQPLECARCWTEYGIRHFPCPSPESKLQNRCVGKD
Sbjct: 1 MSYGSIARGGGLGSRGPFGGPSRQGCQPLECARCWTEYGIRHFPCPSPESKLQNRCVGKD 60
Query: 61 GEGDLGPAGTPIVPRARKRGPGVAPEGSRMPEPTSSPTIGPRKDSAAGPHGRMAGPSTTR 120
GEGDLGPAGTPIVPRARKRGPGVAPEGSRMPEPTSSPTIGPRKDSAAGPHGRMAGPSTTR
Sbjct: 61 GEGDLGPAGTPIVPRARKRGPGVAPEGSRMPEPTSSPTIGPRKDSAAGPHGRMAGPSTTR 120
Query: 121 AKKRKPNFCPQETEVLVSKVSKHHQLLFGTGLLKAEPTRRYRVWSRILQAVNALGYCRRD 180
AKKRKPNFCPQETEVLVSKVSKHHQLLFGTGLLKAEPTRRYRVWSRILQAVNALGYCRRD
Sbjct: 121 AKKRKPNFCPQETEVLVSKVSKHHQLLFGTGLLKAEPTRRYRVWSRILQAVNALGYCRRD 180
Query: 181 VVDLKHKWRDLRAVVRRKLGDLRKAAHGPSPGSGKPQALALTPVEQVVAKTFSCQALPSE 240
VVDLKHKWRDLRAVVRRKLGDLRKAAHGPSPGSGKPQALALTPVEQVVAKTFSCQALPSE
Sbjct: 181 VVDLKHKWRDLRAVVRRKLGDLRKAAHGPSPGSGKPQALALTPVEQVVAKTFSCQALPSE 240
Query: 241 GFSLEPPRATQVDPCNLQELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHT 300
GFSLEPPRATQVDPCNLQELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHT
Sbjct: 241 GFSLEPPRATQVDPCNLQELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHT 300
Query: 301 AQQETNKTIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKI 360
AQQETNKTIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKI
Sbjct: 301 AQQETNKTIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKI 360
Query: 361 AEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEEDLEAIR 420
AEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEEDLEAIR
Sbjct: 361 AEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEEDLEAIR 420
Query: 421 LREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASR 480
LREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASR
Sbjct: 421 LREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASR 480
Query: 481 HQLQRHKIKCCFLSAGVTALLVIIIIIATSVRK 513
HQLQRHKIKCCFLSAGVTALLVIIIIIATSVRK
Sbjct: 481 HQLQRHKIKCCFLSAGVTALLVIIIIIATSVRK 513
>gi|170932494 syntaxin 7 [Homo sapiens]
Length = 261
Score = 137 bits (344), Expect = 3e-32
Identities = 81/249 (32%), Positives = 138/249 (55%), Gaps = 5/249 (2%)
Query: 259 ELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQ 318
+L Q +S+N+ +I ++R+L LGTP D+ ELR L QQ TN+ + +K+
Sbjct: 13 QLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKE 72
Query: 319 MAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQS 378
L + P E+ +Q + Q DRL + + ++ + VQ++ AE+ + + + S+ S
Sbjct: 73 FGSL--PTTPSEQ-RQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVS 129
Query: 379 PQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAILQMESNLLDVNQ 438
F E + E+ ++ Q Q Q +ITE+DL I RE +I Q+E++++D+N+
Sbjct: 130 --GSFPEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINE 187
Query: 439 IIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIKCCFLSAGVT 498
I KDL M+ EQG+ +DSIEA++E A H + A Q L+ A+ +Q + K C + V
Sbjct: 188 IFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVI 247
Query: 499 ALLVIIIII 507
+ +I +II
Sbjct: 248 GVAIISLII 256
>gi|28933465 syntaxin 12 [Homo sapiens]
Length = 276
Score = 135 bits (339), Expect = 1e-31
Identities = 89/254 (35%), Positives = 144/254 (56%), Gaps = 11/254 (4%)
Query: 256 NLQELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASS 315
+ + Q S N+ RI+ + ++ + LGT D+ +L+++L Q TN+ +
Sbjct: 21 DFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQLQHSTNQLAKETNEL 80
Query: 316 VKQMAEL-LRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRG 374
+K++ L L S ++R Q+R Q +RL S A+ + VQ++++EK + + A+ G
Sbjct: 81 LKELGSLPLPLSTSEQR--QQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIARARAG 138
Query: 375 SKQSPQAPFAELADDEKVFNGSDNMW-QGQEQALLPDITEEDLEAIRLREEAILQMESNL 433
S+ S + E ++ V S W Q Q Q ITE+DLE I+ RE AI Q+E+++
Sbjct: 139 SRLSAEERQRE---EQLVSFDSHEEWNQMQSQEDEVAITEQDLELIKERETAIRQLEADI 195
Query: 434 LDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIKCCFL 493
LDVNQI KDLA M+ +QG+ +DSIEA++E++ H E A + L A+ +Q + K K C L
Sbjct: 196 LDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRK-KMCIL 254
Query: 494 SAGVTALLVIIIII 507
V L VII+I+
Sbjct: 255 ---VLVLSVIILIL 265
>gi|37537558 nuclear apoptosis inducing factor 1 [Homo sapiens]
Length = 327
Score = 67.8 bits (164), Expect = 2e-11
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 26/157 (16%)
Query: 121 AKKRKPNFCPQETEVLVSKVSKHHQLLFGTGLLKAEPTRRYRVWSRILQAVNALGYCRRD 180
AKKRK NF +E E++V ++ LL + W IL+ VNA+ CRR+
Sbjct: 5 AKKRKMNFSEREVEIIVEELELKKHLLVNHFNAGVPLAAKSAAWHGILRRVNAVATCRRE 64
Query: 181 VVDLKHKWRDLRAVVRRKLGDLRKAAHG---PSP----GSGKP-------------QALA 220
+ ++K KW DL+ VRRK+ +R A G P P G+G P +
Sbjct: 65 LPEVKKKWSDLKTEVRRKVAQVRAAVEGGEAPGPTEEDGAGGPGTGGGSGGGGPAVAPVL 124
Query: 221 LTPVEQVVAKTFSCQALPSEGFSLEPPRATQVDPCNL 257
LTP++Q + L E + P T++ P L
Sbjct: 125 LTPMQQRICN------LLGEATIISLPSTTEIHPVAL 155
>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
Length = 288
Score = 61.2 bits (147), Expect = 2e-09
Identities = 55/264 (20%), Positives = 124/264 (46%), Gaps = 24/264 (9%)
Query: 262 QEMSANVFRINSSVTSLERSLQS-LGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMA 320
+E+ ++ +I V ++++ L P+ ++++ L ++ NK I +A+ ++
Sbjct: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEEL----EDLNKEIKKTANKIRAKL 92
Query: 321 ELLRSSCPQER--------LQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLP-MA 371
+ + S Q+ L+ R Q L + +A+ Y Q E+S+ +
Sbjct: 93 KAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQL 152
Query: 372 QRGSKQSPQAPFAELADDEK--VFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAILQM 429
+ + + E+ + K +F SD + Q IT + L I R + I+++
Sbjct: 153 EITGRTTTDDELEEMLESGKPSIFT-SDIISDSQ-------ITRQALNEIESRHKDIMKL 204
Query: 430 ESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIK 489
E+++ +++++ D+A V QGE +++IE ++ A+ + E A++ A ++Q + + K
Sbjct: 205 ETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKK 264
Query: 490 CCFLSAGVTALLVIIIIIATSVRK 513
++ V + +I +II SV K
Sbjct: 265 WIIIAVSVVLVAIIALIIGLSVGK 288
>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
Length = 287
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/263 (22%), Positives = 127/263 (48%), Gaps = 26/263 (9%)
Query: 262 QEMSANVFRINSSVTSLERSLQS-LGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMA 320
+E+ ++ +I V ++++ L P+ ++++ L ++ NK I +A+ ++
Sbjct: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEEL----EDLNKEIKKTANKIRAKL 92
Query: 321 ELLRSSCPQER--------LQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLP-MA 371
+ + S Q+ L+ R Q L + +A+ Y Q E+S+ +
Sbjct: 93 KAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQL 152
Query: 372 QRGSKQSPQAPFAELADDEK--VFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAILQM 429
+ + + E+ + K +F SD + Q IT + L I R + I+++
Sbjct: 153 EITGRTTTDDELEEMLESGKPSIFT-SDIISDSQ-------ITRQALNEIESRHKDIMKL 204
Query: 430 ESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIK 489
E+++ +++++ D+A V QGE +++IE ++ A+ + E A++ A ++Q + + K
Sbjct: 205 ETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARR-K 263
Query: 490 CCFLSAGVTALLVII-IIIATSV 511
F+ V LLVI+ II+AT++
Sbjct: 264 LMFIIICVIVLLVILGIILATTL 286
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 54.7 bits (130), Expect = 2e-07
Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 4/142 (2%)
Query: 114 AGPSTTRAKKRKPNFCPQETEVLVSKVSKHHQLLFGTGLLKAEPTRRYRVWSRILQAVNA 173
AG + + RKP F +E ++L+ +V H+ L+G + R RVW I +N
Sbjct: 6 AGEAEETTRLRKPRFSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDGIAAKING 65
Query: 174 LGYCRRDVVDLKHKWRDLRAVVRRKLGDLRKAAHGPSPGSGKPQALALTPVEQVVAKTFS 233
+ +R +++ +W D + + KL + + G P + + E + A
Sbjct: 66 ITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAA---EDAFSAEEETIFAILGP 122
Query: 234 CQALPSEGFSL-EPPRATQVDP 254
A P G EPP A P
Sbjct: 123 GVAAPGAGAGAEEPPAAPSSQP 144
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 52.8 bits (125), Expect = 8e-07
Identities = 54/263 (20%), Positives = 122/263 (46%), Gaps = 24/263 (9%)
Query: 259 ELFQEMSANVFRINSSVTSLERSLQS-LGTPSDTQELRDSLHTAQQETNKTIAASASSVK 317
E +E+ + +I +V ++R + L +P+ ++ ++ L + KT S +K
Sbjct: 35 EQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLK 94
Query: 318 QMAELLRSSCPQERLQQERPQLDRLKTQLS-------DAIQCYGVVQKKIAEKSRALLPM 370
+ + + +E L + L KTQ S + + Y Q E+ + +
Sbjct: 95 SIEQSIEQ---EEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRI-- 149
Query: 371 AQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPD--ITEEDLEAIRLREEAILQ 428
QR + + + +E +D + +G+ ++ ++ D I+++ L I R I++
Sbjct: 150 -QRQLEITGRTTTSEELED-MLESGNPAIFAS---GIIMDSSISKQALSEIETRHSEIIK 204
Query: 429 MESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKI 488
+E+++ +++ + D+A +V QGE +D IE ++E A + E A A ++Q + +
Sbjct: 205 LENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRK 264
Query: 489 KCCFLSAGVTALLVIIIIIATSV 511
K + +++ I+IA++V
Sbjct: 265 KIMI----IICCVILGIVIASTV 283
>gi|4759184 syntaxin 3 [Homo sapiens]
Length = 289
Score = 52.8 bits (125), Expect = 8e-07
Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 17/257 (6%)
Query: 262 QEMSANVFRINSSVTSLERSLQS-LGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMA 320
+E N+ +I+ V ++ L P + +D L E K + +K M
Sbjct: 40 EETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSME 99
Query: 321 ELL-----RSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLP-MAQRG 374
+ + RSS L+ + Q L + + + Y Q E+S+ + +
Sbjct: 100 KHIEEDEVRSSAD---LRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEIT 156
Query: 375 SKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAILQMESNLL 434
K++ E+ + + + Q I+++ L I R + I+++ES++
Sbjct: 157 GKKTTDEELEEMLESGNPAIFTSGIIDSQ-------ISKQALSEIEGRHKDIVRLESSIK 209
Query: 435 DVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIKCCFLS 494
+++ + D+A +V QGE +D+IE ++ H E AR A ++Q Q K +
Sbjct: 210 ELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIV 269
Query: 495 AGVTALLVIIIIIATSV 511
V L ++ +II SV
Sbjct: 270 LVVVLLGILALIIGLSV 286
>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
Length = 325
Score = 52.4 bits (124), Expect = 1e-06
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 28/278 (10%)
Query: 241 GFSLEPPRA---TQVDPCNLQELFQEMSANVFRINSSV---TSLERSLQSLGTPSDTQEL 294
G SL+P A T+ P + E+ +V RI + SL + T D+ E
Sbjct: 59 GISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEE 118
Query: 295 RDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQER------LQQERPQLDRLKTQLSD 348
++ QE + +V+ + R+ QE + L L T
Sbjct: 119 EHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRH 178
Query: 349 AIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALL 408
A Y K E+S+ + P + DD +++ ++Q +L
Sbjct: 179 AQSGYLKRMKNREERSQHFFDTS---------VPLMDDGDDNTLYHRGFT----EDQLVL 225
Query: 409 PDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHA 468
E++ + RE I Q+ ++ D+N+I +DL +M+ EQG +D I+ ++E +
Sbjct: 226 ---VEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKT 282
Query: 469 EAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIII 506
E + L A ++Q + K+ + + +L+++++
Sbjct: 283 EDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 320
>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
Length = 308
Score = 52.4 bits (124), Expect = 1e-06
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 28/278 (10%)
Query: 241 GFSLEPPRA---TQVDPCNLQELFQEMSANVFRINSSV---TSLERSLQSLGTPSDTQEL 294
G SL+P A T+ P + E+ +V RI + SL + T D+ E
Sbjct: 42 GISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEE 101
Query: 295 RDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQER------LQQERPQLDRLKTQLSD 348
++ QE + +V+ + R+ QE + L L T
Sbjct: 102 EHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRH 161
Query: 349 AIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALL 408
A Y K E+S+ + P + DD +++ ++Q +L
Sbjct: 162 AQSGYLKRMKNREERSQHFFDTS---------VPLMDDGDDNTLYHRGFT----EDQLVL 208
Query: 409 PDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHA 468
E++ + RE I Q+ ++ D+N+I +DL +M+ EQG +D I+ ++E +
Sbjct: 209 ---VEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKT 265
Query: 469 EAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIII 506
E + L A ++Q + K+ + + +L+++++
Sbjct: 266 EDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 303
>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
Length = 321
Score = 52.4 bits (124), Expect = 1e-06
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 28/278 (10%)
Query: 241 GFSLEPPRA---TQVDPCNLQELFQEMSANVFRINSSV---TSLERSLQSLGTPSDTQEL 294
G SL+P A T+ P + E+ +V RI + SL + T D+ E
Sbjct: 55 GISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEE 114
Query: 295 RDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQER------LQQERPQLDRLKTQLSD 348
++ QE + +V+ + R+ QE + L L T
Sbjct: 115 EHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRH 174
Query: 349 AIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALL 408
A Y K E+S+ + P + DD +++ ++Q +L
Sbjct: 175 AQSGYLKRMKNREERSQHFFDTS---------VPLMDDGDDNTLYHRGFT----EDQLVL 221
Query: 409 PDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHA 468
E++ + RE I Q+ ++ D+N+I +DL +M+ EQG +D I+ ++E +
Sbjct: 222 ---VEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKT 278
Query: 469 EAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIII 506
E + L A ++Q + K+ + + +L+++++
Sbjct: 279 EDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 316
>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
Length = 304
Score = 52.4 bits (124), Expect = 1e-06
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 28/278 (10%)
Query: 241 GFSLEPPRA---TQVDPCNLQELFQEMSANVFRINSSV---TSLERSLQSLGTPSDTQEL 294
G SL+P A T+ P + E+ +V RI + SL + T D+ E
Sbjct: 38 GISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEE 97
Query: 295 RDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQER------LQQERPQLDRLKTQLSD 348
++ QE + +V+ + R+ QE + L L T
Sbjct: 98 EHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRH 157
Query: 349 AIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALL 408
A Y K E+S+ + P + DD +++ ++Q +L
Sbjct: 158 AQSGYLKRMKNREERSQHFFDTS---------VPLMDDGDDNTLYHRGFT----EDQLVL 204
Query: 409 PDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHA 468
E++ + RE I Q+ ++ D+N+I +DL +M+ EQG +D I+ ++E +
Sbjct: 205 ---VEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKT 261
Query: 469 EAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIII 506
E + L A ++Q + K+ + + +L+++++
Sbjct: 262 EDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 299
>gi|58761537 hypothetical protein LOC84437 [Homo sapiens]
Length = 345
Score = 52.0 bits (123), Expect = 1e-06
Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 5/96 (5%)
Query: 122 KKRKPNFCPQETEVLVSKVSKHHQLLFGTGLLKAEPTRRYRVWSRILQAVNALGYC-RRD 180
+KRK NF QET+ L+ +++K +++F L + W I Q VNA+G +R
Sbjct: 6 RKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGEQRT 65
Query: 181 VVDLKHKWRDLRAVVRRKLGDLRKAAHGPSPGSGKP 216
++K ++ D RA+++RK R A+ GSG P
Sbjct: 66 GTEVKRRYLDWRALMKRK----RMKANIKLVGSGFP 97
>gi|16418379 syntaxin 1B [Homo sapiens]
Length = 288
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/224 (20%), Positives = 102/224 (45%), Gaps = 17/224 (7%)
Query: 292 QELRDSLHTAQQETNKT---IAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSD 348
QEL D ++ NK + A S++Q L RSS L+ + Q L + +
Sbjct: 72 QELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSAD---LRIRKTQHSTLSRKFVE 128
Query: 349 AIQCYGVVQKKIAEKSRALLP-MAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQAL 407
+ Y Q K ++ + + + + + ++ + K+ +D++ +
Sbjct: 129 VMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQ--- 185
Query: 408 LPDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSH 467
+T++ L I R I+++E+++ +++ + D+A +V QGE +D IE ++E + +
Sbjct: 186 ---MTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDY 242
Query: 468 AEAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIIIIATSV 511
E A A ++Q + + K + +V+ +++A+S+
Sbjct: 243 VERAVSDTKKAVKYQSKARRKKIMI----IICCVVLGVVLASSI 282
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 50.1 bits (118), Expect = 5e-06
Identities = 51/242 (21%), Positives = 100/242 (41%), Gaps = 22/242 (9%)
Query: 251 QVDPCNLQELFQEMSANVFRINSSVTSLERSLQSL-----GTPSDTQELRDSLHTAQQET 305
++D N + ++ A+ + LE Q+L GT + ++ +S+ AQ++
Sbjct: 12 KLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKL 71
Query: 306 NKTIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSR 365
+ + + +A L R R+Q +LDR + +L+ A+Q +K E R
Sbjct: 72 EQAEKKATDAEADVASLNR------RIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
Query: 366 ALLPMAQRGSKQSPQAPFAE--LADDEKVFNGSDNMWQ--GQEQALLPDITEEDLEAIRL 421
+ + R K + E L + + + SD ++ ++ +L E E +
Sbjct: 126 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 185
Query: 422 REEAILQMESNLLDVNQIIKDLASMVSEQG-------EAVDSIEASLEAASSHAEAARQL 474
E Q+E L ++Q +K L + E E + +E L+ A + AE A +
Sbjct: 186 AESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERS 245
Query: 475 LA 476
+A
Sbjct: 246 VA 247
>gi|20149560 syntaxin 4 [Homo sapiens]
Length = 297
Score = 48.9 bits (115), Expect = 1e-05
Identities = 51/255 (20%), Positives = 109/255 (42%), Gaps = 21/255 (8%)
Query: 268 VFRINSSVTSLERS-LQSLGTPSDTQELRDSLHTAQQETN---KTIAASASSVKQMAELL 323
+ ++ + V LE+ + L TP + ++ L + E + I +++ E
Sbjct: 52 IVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEA 111
Query: 324 RSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPF 383
+ + + Q L Q + I +Q + EK+ + ++ +
Sbjct: 112 DENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERI-------RRQLKITN 164
Query: 384 AELADDEKVFNGSDNMWQGQEQALLPDI------TEEDLEAIRLREEAILQMESNLLDVN 437
A + DE++ D+ GQ + + +I T + L I R I Q+E ++ +++
Sbjct: 165 AGMVSDEELEQMLDS---GQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELH 221
Query: 438 QIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIKCCF-LSAG 496
I LA+ V QGE ++ IE ++ +++ + E ++ + A +Q + K K +
Sbjct: 222 DIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVS 281
Query: 497 VTALLVIIIIIATSV 511
+T +L+ +II T V
Sbjct: 282 ITVVLLAVIIGVTVV 296
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/215 (22%), Positives = 87/215 (40%), Gaps = 12/215 (5%)
Query: 270 RINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQ 329
++ + SL++ L+ GT + + ++L AQ++ + + +A L R
Sbjct: 38 QLEDELVSLQKKLK--GTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR----- 90
Query: 330 ERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADD 389
R+Q +LDR + +L+ A+Q +K E R + + R K + E+
Sbjct: 91 -RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
Query: 390 EKVFNGSDNMWQGQEQALLPDITEEDL----EAIRLREEAILQMESNLLDVNQIIKDLAS 445
E D + +E A I E DL E L E + Q+E L ++Q +K L +
Sbjct: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA 209
Query: 446 MVSEQGEAVDSIEASLEAASSHAEAARQLLAGASR 480
+ + D E ++ S + A A R
Sbjct: 210 AEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/215 (22%), Positives = 87/215 (40%), Gaps = 12/215 (5%)
Query: 270 RINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQ 329
++ + SL++ L+ GT + + ++L AQ++ + + +A L R
Sbjct: 38 QLEDELVSLQKKLK--GTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR----- 90
Query: 330 ERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADD 389
R+Q +LDR + +L+ A+Q +K E R + + R K + E+
Sbjct: 91 -RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
Query: 390 EKVFNGSDNMWQGQEQALLPDITEEDL----EAIRLREEAILQMESNLLDVNQIIKDLAS 445
E D + +E A I E DL E L E + Q+E L ++Q +K L +
Sbjct: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMA 209
Query: 446 MVSEQGEAVDSIEASLEAASSHAEAARQLLAGASR 480
+ + D E ++ S + A A R
Sbjct: 210 AEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 47.0 bits (110), Expect = 4e-05
Identities = 50/213 (23%), Positives = 84/213 (39%), Gaps = 12/213 (5%)
Query: 272 NSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQER 331
+SS+ ++ R ++SL +D E R T Q+E + ++ +A L R R
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAG--TLQRELDHERKLRETAEADVASLNR------R 55
Query: 332 LQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEK 391
+Q +LDR + +L+ A+Q +K E R + + R K + E+ E
Sbjct: 56 IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEA 115
Query: 392 VFNGSDNMWQGQEQALLPDITEEDL----EAIRLREEAILQMESNLLDVNQIIKDLASMV 447
D + +E A I E DL E L E ++E L V +K L +
Sbjct: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
Query: 448 SEQGEAVDSIEASLEAASSHAEAARQLLAGASR 480
+ + D E ++ S + A A R
Sbjct: 176 EKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 208
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 47.0 bits (110), Expect = 4e-05
Identities = 47/215 (21%), Positives = 84/215 (39%), Gaps = 12/215 (5%)
Query: 270 RINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQ 329
++ + SL++ L+ GT + + ++L AQ++ + + +A L R
Sbjct: 38 QLEDELVSLQKKLK--GTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR----- 90
Query: 330 ERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADD 389
R+Q +LDR + +L+ A+Q +K E R + + R K + E+
Sbjct: 91 -RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
Query: 390 EKVFNGSDNMWQGQEQALLPDITEEDL----EAIRLREEAILQMESNLLDVNQIIKDLAS 445
E D + +E A I E DL E L E ++E L V +K L +
Sbjct: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
Query: 446 MVSEQGEAVDSIEASLEAASSHAEAARQLLAGASR 480
+ + D E ++ S + A A R
Sbjct: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 47.0 bits (110), Expect = 4e-05
Identities = 47/215 (21%), Positives = 84/215 (39%), Gaps = 12/215 (5%)
Query: 270 RINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQ 329
++ + SL++ L+ GT + + ++L AQ++ + + +A L R
Sbjct: 38 QLEDELVSLQKKLK--GTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR----- 90
Query: 330 ERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADD 389
R+Q +LDR + +L+ A+Q +K E R + + R K + E+
Sbjct: 91 -RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 149
Query: 390 EKVFNGSDNMWQGQEQALLPDITEEDL----EAIRLREEAILQMESNLLDVNQIIKDLAS 445
E D + +E A I E DL E L E ++E L V +K L +
Sbjct: 150 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 209
Query: 446 MVSEQGEAVDSIEASLEAASSHAEAARQLLAGASR 480
+ + D E ++ S + A A R
Sbjct: 210 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAER 244
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/189 (23%), Positives = 74/189 (39%), Gaps = 10/189 (5%)
Query: 296 DSLHTAQQETNKTIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGV 355
+ LH A+ A+A + +A L R R+Q +LDR + +L+ A+Q
Sbjct: 62 EELHKAEDSLLAAEEAAAKAEADVASLNR------RIQLVEEELDRAQERLATALQKLEE 115
Query: 356 VQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEED 415
+K E R + + R K + E+ E D + +E A I E D
Sbjct: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
Query: 416 L----EAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAA 471
L E L E + Q+E L ++Q +K L + + + D E ++ S + A
Sbjct: 176 LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA 235
Query: 472 RQLLAGASR 480
A R
Sbjct: 236 ETRAEFAER 244
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/220 (21%), Positives = 94/220 (42%), Gaps = 23/220 (10%)
Query: 270 RINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQ 329
++ + ++++ L+ GT + + ++L AQ++ +A + ++A L R
Sbjct: 39 QLEDELAAMQKKLK--GTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNR----- 91
Query: 330 ERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAE--LA 387
R+Q +LDR + +L+ A+Q +K E R + + R K + E L
Sbjct: 92 -RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 150
Query: 388 DDEKVFNGSDNMWQGQEQALLPDITEEDL----EAIRLREEAILQMESNLLDVNQIIKDL 443
+ + + +D ++ + L+ I E DL E L E ++E L +V +K L
Sbjct: 151 EAKHIAEEADRKYEEVARKLV--IIEGDLERTEERAELAESKCSELEEELKNVTNNLKSL 208
Query: 444 ASMVSEQGEAVDSIEA-------SLEAASSHAEAARQLLA 476
+ + + D E L+ A + AE A + +A
Sbjct: 209 EAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVA 248
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 44.3 bits (103), Expect = 3e-04
Identities = 49/242 (20%), Positives = 97/242 (40%), Gaps = 22/242 (9%)
Query: 251 QVDPCNLQELFQEMSANVFRINSSVTSLERSLQSL-----GTPSDTQELRDSLHTAQQET 305
++D N + ++ A+ + LE Q+L GT + ++ +S+ AQ++
Sbjct: 12 KLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKL 71
Query: 306 NKTIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSR 365
+ + + +A L R R+Q +LDR + +L+ A+Q +K E R
Sbjct: 72 EQAEKKATDAEADVASLNR------RIQLVEEELDRAQERLATALQKLEEAEKAADESER 125
Query: 366 ALLPMAQRGSKQSPQAPFAE--LADDEKVFNGSDNMWQ--GQEQALLPDITEEDLEAIRL 421
+ + R K + E L + + + SD ++ ++ +L E E +
Sbjct: 126 GMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEV 185
Query: 422 REEAILQMESNLLDVNQIIKDLASMVSEQG-------EAVDSIEASLEAASSHAEAARQL 474
E +E L V +K L + + E + +E L+ A + AE A +
Sbjct: 186 AESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERS 245
Query: 475 LA 476
+A
Sbjct: 246 VA 247
>gi|117956403 rabaptin, RAB GTPase binding effector protein 2 [Homo
sapiens]
Length = 569
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/272 (22%), Positives = 107/272 (39%), Gaps = 26/272 (9%)
Query: 208 GPSPGSGKPQAL-ALTPVEQVVAKTFSCQALPSEGFSLEPPRATQVDPCNLQELFQEMSA 266
G S PQ+ L+P ++ A S L EG L PP V ++L E
Sbjct: 242 GVGSSSSLPQSRQGLSPEQEETASLVSTGTLVPEGIYLPPPGYQLVPDTQWEQLQTEGR- 300
Query: 267 NVFRINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAELLRSS 326
L++ L+S+ D EL++ L + ++ K + + V+ +LLR+
Sbjct: 301 ----------QLQKDLESVSRERD--ELQEGLRRSNEDCAKQMQVLLAQVQNSEQLLRTL 348
Query: 327 CPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAEL 386
QER QL +L +C K++ E+++ L A++ +PQ E
Sbjct: 349 QGTVSQAQERVQLQ--MAELVTTHKCLHHEVKRLNEENQGL--RAEQLPSSAPQGSQQEQ 404
Query: 387 ADDEKVFNGSDNMWQ-----GQEQALLPDITEEDLEAIRLREEAILQMESNLLDVNQIIK 441
++E + + + Q QE E E +R+ I+ + L +
Sbjct: 405 GEEESLPSSVPELQQLLCCTRQEARARLQAQEHGAERLRIE---IVTLREALEEETVARA 461
Query: 442 DLASMVSEQGEAVDSIEASLEAASSHAEAARQ 473
L + Q E + +EASL + + E +Q
Sbjct: 462 SLEGQLRVQREETEVLEASLCSLRTEMERVQQ 493
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 43.9 bits (102), Expect = 4e-04
Identities = 47/217 (21%), Positives = 89/217 (41%), Gaps = 16/217 (7%)
Query: 270 RINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQ 329
++ +T L++ L+ GT + + + L AQ++ T ++ + +A L R
Sbjct: 38 QVEEELTHLQKKLK--GTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNR----- 90
Query: 330 ERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAE--LA 387
R+Q +LDR + +L+ A+Q +K E R + + R K + E L
Sbjct: 91 -RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLK 149
Query: 388 DDEKVFNGSDNMWQGQEQALLPDITEEDLEAIRLREEA----ILQMESNLLDVNQIIKDL 443
+ + + +D ++ + L+ I E +LE R E +E L +V +K L
Sbjct: 150 EAKHIAEEADRKYEEVARKLV--ILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSL 207
Query: 444 ASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASR 480
+ + E D E ++ S + A A R
Sbjct: 208 EAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAER 244
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/189 (23%), Positives = 71/189 (37%), Gaps = 10/189 (5%)
Query: 296 DSLHTAQQETNKTIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGV 355
+ LH A+ A+A + +A L R R+Q +LDR + +L+ A+Q
Sbjct: 62 EELHKAEDSLLAAEEAAAKAEADVASLNR------RIQLVEEELDRAQERLATALQKLEE 115
Query: 356 VQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEED 415
+K E R + + R K + E+ E D + +E A I E D
Sbjct: 116 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 175
Query: 416 L----EAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAA 471
L E L E ++E L V +K L + + + D E ++ S + A
Sbjct: 176 LERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA 235
Query: 472 RQLLAGASR 480
A R
Sbjct: 236 ETRAEFAER 244
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 42.7 bits (99), Expect = 8e-04
Identities = 54/275 (19%), Positives = 113/275 (41%), Gaps = 30/275 (10%)
Query: 252 VDPCNLQELFQEMSANVFRINSSVTSLERS-LQSLGTPSDTQ--ELR---DSLHTAQQET 305
++ N E E +N +N+S LE L L D + EL+ + + T +ET
Sbjct: 733 LEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKET 792
Query: 306 NKTIAASASSVKQMAELL-RSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKS 364
+++S KQ+ +L+ + E+L++ +L + S A++ ++++ I EK
Sbjct: 793 KDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKD 852
Query: 365 RALLPMAQRGS-----------KQSPQAPFA---------ELADDEKVFNGSDNMWQGQ- 403
R+L M + + +QS AP A ELA + N + +
Sbjct: 853 RSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEI 912
Query: 404 --EQALLPDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASL 461
Q ++ D + ++ ++ +E +M+ Q+ + E+ E + S++ ++
Sbjct: 913 KHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTI 972
Query: 462 EAASSHAEAARQLLAGASRHQLQRHKIKCCFLSAG 496
E + RQ + + Q K++ + G
Sbjct: 973 EQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENG 1007
Score = 31.2 bits (69), Expect = 2.4
Identities = 43/227 (18%), Positives = 95/227 (41%), Gaps = 34/227 (14%)
Query: 262 QEMSANVFRINSSVTSLERSL-QSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMA 320
+E+ ++ ++N+ ++ + + + S+ +LR +L +QE N++I+ + + ++
Sbjct: 439 EELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIE 498
Query: 321 ELLRS--------------------------SCPQERLQQERPQLDRLKTQLSDAIQCYG 354
EL R S ++ L E+ ++ +L+ D +
Sbjct: 499 ELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELD 558
Query: 355 VVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEE 414
V ++K+ + AL + +KQ + L D S+ Q + L I +
Sbjct: 559 VQKEKLIQSEVALNDL--HLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQN 616
Query: 415 DLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASL 461
+ E R+R E M+S D N KD +++ E+ V +++ +L
Sbjct: 617 EEELSRIRNEL---MQSLNQDSNSNFKD--TLLKEREAEVRNLKQNL 658
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/233 (21%), Positives = 100/233 (42%), Gaps = 31/233 (13%)
Query: 251 QVDPCNLQELFQE---MSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNK 307
+V +Q+L +E + A + R N+S+T+ + +QSL D ++R T Q++ +
Sbjct: 1362 EVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSL--KEDLNKVRTEKETIQKDLDA 1419
Query: 308 TIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRAL 367
I VK + ++ + ++ + Q + LK Q Q K+ E S
Sbjct: 1420 KIIDIQEKVKTITQVKKIG------RRYKTQYEELKAQ-----------QDKVMETS--- 1459
Query: 368 LPMAQRGSKQSPQAPFAELADDEKVFNGSD---NMWQGQEQALLPDITEEDLEAIRLREE 424
G Q E+ + ++ N ++ + Q + L ++E++ EA L+E+
Sbjct: 1460 --AQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQ 1517
Query: 425 AILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAG 477
+ Q++S L + Q ++D + + + + E A A++ LAG
Sbjct: 1518 TV-QLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAG 1569
Score = 38.5 bits (88), Expect = 0.015
Identities = 37/189 (19%), Positives = 82/189 (43%), Gaps = 21/189 (11%)
Query: 261 FQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMA 320
F+ R V LER LQ EL+DSL+ +++ + +A ++ Q
Sbjct: 1214 FEVAQVESLRYRQRVELLERELQ---------ELQDSLNAEREK----VQVTAKTMAQHE 1260
Query: 321 ELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQ 380
EL++ + + + L K +L +Q +Q K+ + +LP+ + ++ S +
Sbjct: 1261 ELMKKTETMNVVMETNKMLREEKERLEQDLQ---QMQAKVRKLELDILPLQEANAELSEK 1317
Query: 381 APFAELADDEKVFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAILQMESNLLDVNQII 440
+ L ++K+ W+ + Q L+ + D E R + + + E + + Q+
Sbjct: 1318 S--GMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYR---KLLSEKEVHTKRIQQLT 1372
Query: 441 KDLASMVSE 449
+++ + +E
Sbjct: 1373 EEIGRLKAE 1381
Score = 34.7 bits (78), Expect = 0.21
Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 17/184 (9%)
Query: 248 RATQVDPCNLQELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNK 307
R T+ +L+E + ++NV + + VTSLE SL T+E+R ++ +E+ +
Sbjct: 942 RQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNK--EKQVTEEVRKNIEVRLKESAE 999
Query: 308 TIAASASSVKQMAELLRSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRAL 367
K++ E+ + QE +R ++ ++ QLS+ + VQ ++ E
Sbjct: 1000 ---FQTQLEKKLMEVEKEK--QELQDDKRRAIESMEQQLSELKKTLSSVQNEVQE----A 1050
Query: 368 LPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAIL 427
L A QA + + K+ + N + E+ L+ + D+EA++ +E +
Sbjct: 1051 LQRASTALSNEQQAR-RDCQEQAKIAVEAQNKY---ERELM--LHAADVEALQAAKEQVS 1104
Query: 428 QMES 431
+M S
Sbjct: 1105 KMAS 1108
Score = 31.2 bits (69), Expect = 2.4
Identities = 37/168 (22%), Positives = 70/168 (41%), Gaps = 27/168 (16%)
Query: 288 PSDTQELRDSLHTAQQETNKTIAASASSVKQMAELL----RSSCPQERLQQE-------- 335
PS +Q + E+ + I A A+ +KQ+ E+ + E++Q E
Sbjct: 645 PSTSQTVSTPAPVPVIESTEAIEAKAA-LKQLQEIFENYKKEKAENEKIQNEQLEKLQEQ 703
Query: 336 ----RPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEK 391
R Q ++ TQL A + Y ++Q + R + + +R K + A E+
Sbjct: 704 VTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT-----ATTQKQEQ 758
Query: 392 VFNGSDNMWQG-QEQALLPDITEEDL----EAIRLREEAILQMESNLL 434
+ N +G E+ + ++ E+L E ++L E + Q +LL
Sbjct: 759 IINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLL 806
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,829,126
Number of Sequences: 37866
Number of extensions: 1095697
Number of successful extensions: 6958
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 277
Number of HSP's that attempted gapping in prelim test: 6428
Number of HSP's gapped (non-prelim): 823
length of query: 513
length of database: 18,247,518
effective HSP length: 107
effective length of query: 406
effective length of database: 14,195,856
effective search space: 5763517536
effective search space used: 5763517536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.