Guide to the Human Genome
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Search of human proteins with 223942018

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223942018 jumonji domain containing 5 isoform 1 [Homo
sapiens]
         (454 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223942018 jumonji domain containing 5 isoform 1 [Homo sapiens]     941   0.0  
gi|223942014 jumonji domain containing 5 isoform 2 [Homo sapiens]     863   0.0  
gi|89242134 hypothetical protein LOC129450 [Homo sapiens]             101   1e-21
gi|167860114 jumonji domain containing 7 [Homo sapiens]                94   2e-19
gi|148596936 hypoxia-inducible factor 1, alpha subunit inhibitor...    94   3e-19
gi|21314714 Hspb associated protein 1 [Homo sapiens]                   91   3e-18
gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]                        67   4e-11
gi|239788849 jumonji domain containing 4 isoform 2 [Homo sapiens]      50   6e-06
gi|239788847 jumonji domain containing 4 isoform 1 [Homo sapiens]      50   6e-06
gi|56090146 jumonji domain containing 8 [Homo sapiens]                 44   4e-04
gi|125988395 jumonji domain containing 6 isoform 1 [Homo sapiens]      40   0.006
gi|125988389 jumonji domain containing 6 isoform 2 [Homo sapiens]      40   0.006
gi|106879206 chromosome 14 open reading frame 169 [Homo sapiens]       37   0.048
gi|4885323 G protein-coupled receptor 37 [Homo sapiens]                32   1.2  
gi|169205008 PREDICTED: hypothetical protein [Homo sapiens]            32   1.6  
gi|169205607 PREDICTED: hypothetical protein [Homo sapiens]            32   1.6  
gi|169204476 PREDICTED: hypothetical protein [Homo sapiens]            32   1.6  
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    32   1.6  
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    32   1.6  
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   32   1.6  
gi|156416026 zinc finger protein 219 [Homo sapiens]                    32   1.6  
gi|156415998 zinc finger protein 219 [Homo sapiens]                    32   1.6  
gi|156415996 zinc finger protein 219 [Homo sapiens]                    32   1.6  
gi|223718074 hydroxysteroid (17-beta) dehydrogenase 1 [Homo sapi...    31   2.0  
gi|51944974 tumor suppressor candidate 1 [Homo sapiens]                30   3.5  
gi|34787409 hypothetical protein LOC57148 [Homo sapiens]               30   4.5  
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]                  30   4.5  
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]                  30   4.5  
gi|27436971 potassium voltage-gated channel, shaker-related subf...    30   4.5  
gi|39930351 dynamin binding protein [Homo sapiens]                     30   5.9  

>gi|223942018 jumonji domain containing 5 isoform 1 [Homo sapiens]
          Length = 454

 Score =  941 bits (2433), Expect = 0.0
 Identities = 454/454 (100%), Positives = 454/454 (100%)

Query: 1   MSREKCSPGEGAEEGRGSEASGLKASAGHGTEPAGGGPMAGDTHCPAEPLAREGTLWEAL 60
           MSREKCSPGEGAEEGRGSEASGLKASAGHGTEPAGGGPMAGDTHCPAEPLAREGTLWEAL
Sbjct: 1   MSREKCSPGEGAEEGRGSEASGLKASAGHGTEPAGGGPMAGDTHCPAEPLAREGTLWEAL 60

Query: 61  RALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGRRDECLQSSEVILDYSWEKLNTG 120
           RALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGRRDECLQSSEVILDYSWEKLNTG
Sbjct: 61  RALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGRRDECLQSSEVILDYSWEKLNTG 120

Query: 121 TWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAALRVCDMGLLMGAAILGDILLKVA 180
           TWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAALRVCDMGLLMGAAILGDILLKVA
Sbjct: 121 TWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAALRVCDMGLLMGAAILGDILLKVA 180

Query: 181 AILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVP 240
           AILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVP
Sbjct: 181 AILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVP 240

Query: 241 GRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKY 300
           GRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKY
Sbjct: 241 GRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKY 300

Query: 301 IVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQ 360
           IVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQ
Sbjct: 301 IVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQ 360

Query: 361 DPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFL 420
           DPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFL
Sbjct: 361 DPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFL 420

Query: 421 SCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS 454
           SCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS
Sbjct: 421 SCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS 454


>gi|223942014 jumonji domain containing 5 isoform 2 [Homo sapiens]
          Length = 416

 Score =  863 bits (2231), Expect = 0.0
 Identities = 416/416 (100%), Positives = 416/416 (100%)

Query: 39  MAGDTHCPAEPLAREGTLWEALRALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGR 98
           MAGDTHCPAEPLAREGTLWEALRALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGR
Sbjct: 1   MAGDTHCPAEPLAREGTLWEALRALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGR 60

Query: 99  RDECLQSSEVILDYSWEKLNTGTWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAAL 158
           RDECLQSSEVILDYSWEKLNTGTWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAAL
Sbjct: 61  RDECLQSSEVILDYSWEKLNTGTWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAAL 120

Query: 159 RVCDMGLLMGAAILGDILLKVAAILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKL 218
           RVCDMGLLMGAAILGDILLKVAAILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKL
Sbjct: 121 RVCDMGLLMGAAILGDILLKVAAILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKL 180

Query: 219 EKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVG 278
           EKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVG
Sbjct: 181 EKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVG 240

Query: 279 SRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDG 338
           SRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDG
Sbjct: 241 SRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDG 300

Query: 339 EEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNT 398
           EEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNT
Sbjct: 301 EEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNT 360

Query: 399 SQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS 454
           SQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS
Sbjct: 361 SQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS 416


>gi|89242134 hypothetical protein LOC129450 [Homo sapiens]
          Length = 315

 Score =  101 bits (252), Expect = 1e-21
 Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 39/257 (15%)

Query: 222 VPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGS-- 279
           VPRL   S + F +      +P++L+G+ D  PC  KW+++Y+ ++ G + V + V +  
Sbjct: 8   VPRLEGVSREQFMQHLYPQRKPLVLEGI-DLGPCTSKWTVDYLSQVGGKKEVKIHVAAVA 66

Query: 280 ---------------------RYTDEEWSQTLMTVNE-FISKYIVNEPR-DVGYLAQHQL 316
                                R  +E+  +  ++ +E +  + +  +PR DV  + +   
Sbjct: 67  QMDFISKNFVYRTLPFDQLVQRAAEEKHKEFFVSEDEKYYLRSLGEDPRKDVADIRK--- 123

Query: 317 FDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYI 376
             Q P LK DI  P++      EE+  +        G     H D   N L+QV G+K +
Sbjct: 124 --QFPLLKGDIKFPEFFK----EEQFFSSVFRISSPGLQLWTHYDVMDNLLIQVTGKKRV 177

Query: 377 RLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKY 436
            L+SP+++  LY   T     +  ++++NPDL K+P F+KA    C L  G++LFIP  +
Sbjct: 178 VLFSPRDAQYLYLKGT----KSEVLNIDNPDLAKYPLFSKARRYECSLEAGDVLFIPALW 233

Query: 437 WHYVRALDLSFSVSFWW 453
           +H V + +    V+ +W
Sbjct: 234 FHNVISEEFGVGVNIFW 250


>gi|167860114 jumonji domain containing 7 [Homo sapiens]
          Length = 316

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 71/265 (26%), Positives = 115/265 (43%), Gaps = 34/265 (12%)

Query: 222 VPRLHRPSLQ-HFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEV-GS 279
           VP L +P    HF   ++ P RP I++    HWP +QKWSL Y +   G   V V V   
Sbjct: 29  VPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPD 88

Query: 280 RYTDEEWSQTLMTVNE------FISKYIVNEPRDVGYL-AQHQ---LFDQIPELKQDI-S 328
            Y D       M   E      F+   +    +  G L  Q Q   L  ++P+L  D+ S
Sbjct: 89  GYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLES 148

Query: 329 IPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYI------------ 376
              + S   G+  +  +N W G    ++ LH+D  +N    V G K+             
Sbjct: 149 HVPWASEALGKMPD-AVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIP 207

Query: 377 -RLYSP-----QESGALYPHDTHLLHNTSQVDVE--NPDLEKFPKFAKAPFLSCILSPGE 428
             LY+P      E G     D   +     + ++   PDL ++P +++A  L C +  GE
Sbjct: 208 YELYTPATYQLTEEGTFKVVDEEAMEKVPWIPLDPLAPDLARYPSYSQAQALRCTVRAGE 267

Query: 429 ILFIPVKYWHYVRALDLSFSVSFWW 453
           +L++P  ++H+V+      +V+FW+
Sbjct: 268 MLYLPALWFHHVQQSQGCIAVNFWY 292


>gi|148596936 hypoxia-inducible factor 1, alpha subunit inhibitor
           [Homo sapiens]
          Length = 349

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 72/261 (27%), Positives = 120/261 (45%), Gaps = 30/261 (11%)

Query: 220 KTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGS 279
           + +PRL +   +   E+ +    PV+L      +P + KW LEY+QE  G     V   S
Sbjct: 40  RPIPRLSQSDPR--AEELIENEEPVVLTDTNLVYPAL-KWDLEYLQENIGNGDFSVYSAS 96

Query: 280 R----YTDEEWSQTL-----------MTVNEFISKY--IVNEPRDVGYLAQHQLFDQIP- 321
                Y DE+                M  +EF+ K   I     +     Q  L D +  
Sbjct: 97  THKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGR 156

Query: 322 ELKQDISIPDYCSLGDGEEE----EITINAWF-GPQGTISPLHQDPQQNFLVQVMGRKYI 376
           ++  D    ++  +   + +    ++T N    G +G ++P H D QQNF  Q+ G K  
Sbjct: 157 KIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRC 216

Query: 377 RLYSPQESGALYPHDTHL-LHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVK 435
            L+ P +   LYP+  H      SQVD +NPD E+FP F        ++ PG++L+IP+ 
Sbjct: 217 ILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMY 276

Query: 436 YWHYVRAL---DLSFSVSFWW 453
           +WH++ +L    ++ +V+FW+
Sbjct: 277 WWHHIESLLNGGITITVNFWY 297


>gi|21314714 Hspb associated protein 1 [Homo sapiens]
          Length = 488

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 65/235 (27%), Positives = 114/235 (48%), Gaps = 28/235 (11%)

Query: 242 RPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVG--SRYTDEEWSQTLMTVNEFISK 299
           +P I   +   WP  + W+ +Y+ ++   + +   +G  S  T  ++  T   V   + +
Sbjct: 42  QPAIFCNMVFDWPA-RHWNAKYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEE 100

Query: 300 YI--------VNEP-RD---------VGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEE 341
           ++        ++ P RD           Y     LF+   +L QD+   D+   G   +E
Sbjct: 101 FLTWNCDQSSISGPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQE 160

Query: 342 EITINAWFGPQGTISPLHQDPQQ-NFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNT-- 398
                 W G  G  +P H D    N + QV GRK   L+ P+++  LYP       ++  
Sbjct: 161 S---TLWIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVF 217

Query: 399 SQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALD-LSFSVSFW 452
           S+++V NPDL++FP+F KA   +  LSPG++LF+P  +WHYV ++D ++ S++ W
Sbjct: 218 SKINVVNPDLKRFPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSW 272


>gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]
          Length = 1012

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 50/175 (28%), Positives = 75/175 (42%), Gaps = 14/175 (8%)

Query: 222 VPRLHRPSLQ-HFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEV-GS 279
           VP L +P    HF   ++ P RP I++    HWP +QKWSL Y +   G   V V V   
Sbjct: 29  VPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPD 88

Query: 280 RYTDEEWSQTLMTVNE------FISKYIVNEPRDVGYL-AQHQ---LFDQIPELKQDI-S 328
            Y D       M   E      F+   +    +  G L  Q Q   L  ++P+L  D+ S
Sbjct: 89  GYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLES 148

Query: 329 IPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQE 383
              + S   G+  +  +N W G    ++ LH+D  +N    V G K+   + P +
Sbjct: 149 HVPWASEALGKMPD-AVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSD 202


>gi|239788849 jumonji domain containing 4 isoform 2 [Homo sapiens]
          Length = 447

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 63/251 (25%), Positives = 98/251 (39%), Gaps = 32/251 (12%)

Query: 229 SLQHFREQFLVPGRPVILKGV-ADHWPCMQKW-------SLEYIQEIAGCRTVPVEVGSR 280
           S   F   FL+P  P +        W   ++W         +++    G   VPV     
Sbjct: 86  SYADFVRGFLLPNLPCVFSSAFTQGWGSRRRWVTPAGRPDFDHLLRTYGDVVVPVANCGV 145

Query: 281 YTDEEWSQTLMTVNEFIS---KYI---VNEPRDVGYLAQHQLFDQIPELKQDISIPDYCS 334
                  +  MT+ ++I+   +YI    + PR   YL    L    P ++   ++P Y S
Sbjct: 146 QEYNSNPKEHMTLRDYITYWKEYIQAGYSSPRGCLYLKDWHLCRDFP-VEDVFTLPVYFS 204

Query: 335 ------LGDGEEEEITINAWFGPQGTISPLHQDPQQNFL--VQVMGRKYIRLYSPQESGA 386
                   D  + +     + GP G+ SP H D  ++F   V V GRK   L+ P +  A
Sbjct: 205 SDWLNEFWDALDVDDYRFVYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEA 264

Query: 387 LYPHDTHLLHNTSQVDVENP---DLEKFPKFAKA-PFLSCILSPGEILFIPVKYWHYVRA 442
           L        H     DV +P   D    P+   A P L      GE++F+P  + H V  
Sbjct: 265 LRDR-----HGNLPYDVTSPALCDTHLHPRNQLAGPPLEITQEAGEMVFVPSGWHHQVHN 319

Query: 443 LDLSFSVSFWW 453
           LD + S++  W
Sbjct: 320 LDDTISINHNW 330


>gi|239788847 jumonji domain containing 4 isoform 1 [Homo sapiens]
          Length = 463

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 63/251 (25%), Positives = 98/251 (39%), Gaps = 32/251 (12%)

Query: 229 SLQHFREQFLVPGRPVILKGV-ADHWPCMQKW-------SLEYIQEIAGCRTVPVEVGSR 280
           S   F   FL+P  P +        W   ++W         +++    G   VPV     
Sbjct: 86  SYADFVRGFLLPNLPCVFSSAFTQGWGSRRRWVTPAGRPDFDHLLRTYGDVVVPVANCGV 145

Query: 281 YTDEEWSQTLMTVNEFIS---KYI---VNEPRDVGYLAQHQLFDQIPELKQDISIPDYCS 334
                  +  MT+ ++I+   +YI    + PR   YL    L    P ++   ++P Y S
Sbjct: 146 QEYNSNPKEHMTLRDYITYWKEYIQAGYSSPRGCLYLKDWHLCRDFP-VEDVFTLPVYFS 204

Query: 335 ------LGDGEEEEITINAWFGPQGTISPLHQDPQQNFL--VQVMGRKYIRLYSPQESGA 386
                   D  + +     + GP G+ SP H D  ++F   V V GRK   L+ P +  A
Sbjct: 205 SDWLNEFWDALDVDDYRFVYAGPAGSWSPFHADIFRSFSWSVNVCGRKKWLLFPPGQEEA 264

Query: 387 LYPHDTHLLHNTSQVDVENP---DLEKFPKFAKA-PFLSCILSPGEILFIPVKYWHYVRA 442
           L        H     DV +P   D    P+   A P L      GE++F+P  + H V  
Sbjct: 265 LRDR-----HGNLPYDVTSPALCDTHLHPRNQLAGPPLEITQEAGEMVFVPSGWHHQVHN 319

Query: 443 LDLSFSVSFWW 453
           LD + S++  W
Sbjct: 320 LDDTISINHNW 330


>gi|56090146 jumonji domain containing 8 [Homo sapiens]
          Length = 285

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 48/214 (22%), Positives = 82/214 (38%), Gaps = 22/214 (10%)

Query: 242 RPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYI 301
           RPVIL+G+ D+       S + +    G R V +   + Y+   + +  +   E++ + +
Sbjct: 85  RPVILQGLTDNSRFRALCSRDRLLASFGDRVVRLSTANTYS---YHKVDLPFQEYVEQLL 141

Query: 302 -VNEPRDVG----YLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTIS 356
              +P  +G    Y      F +   L +  S P +  LG        I       G+  
Sbjct: 142 HPQDPTSLGNDTLYFFGDNNFTEWASLFRHYSPPPFGLLGTAPAYSFGIAG----AGSGV 197

Query: 357 PLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAK 416
           P H      +   + GRK   LY P+++   +P+ T L           P          
Sbjct: 198 PFHWHGP-GYSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLRDTYPALPPSARP------ 250

Query: 417 APFLSCILSPGEILFIPVKYWHYVRALDLSFSVS 450
              L C +  GE+L+ P ++WH    LD S  +S
Sbjct: 251 ---LECTIRAGEVLYFPDRWWHATLNLDTSVFIS 281


>gi|125988395 jumonji domain containing 6 isoform 1 [Homo sapiens]
          Length = 414

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 56/244 (22%), Positives = 99/244 (40%), Gaps = 35/244 (14%)

Query: 229 SLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQ 288
           S++ F E++  P +PV+L    + W   +KW+LE ++     R    + G    D +   
Sbjct: 55  SVEEFVERYERPYKPVVLLNAQEGWSAQEKWTLERLKR--KYRNQKFKCGE---DNDGYS 109

Query: 289 TLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIP---ELKQDISIPDYCS---LGDGEEEE 342
             M +  +I +Y+ +   D         + + P   +L +D  +P + +        E+ 
Sbjct: 110 VKMKMKYYI-EYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKR 168

Query: 343 ITINAWF--GPQGTISPLHQDP----QQNFLVQVMGRKYIRLY---SPQE-------SGA 386
                WF  GP  + + +H DP      N LVQ  G K   L+   +P+E        G 
Sbjct: 169 RPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQ--GHKRWCLFPTSTPRELIKVTRDEGG 226

Query: 387 LYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLS 446
               +     N      + P     P+F     L  +  PGE +F+P  +WH V  LD +
Sbjct: 227 NQQDEAITWFNVIYPRTQLPTWP--PEFKP---LEILQKPGETVFVPGGWWHVVLNLDTT 281

Query: 447 FSVS 450
            +++
Sbjct: 282 IAIT 285


>gi|125988389 jumonji domain containing 6 isoform 2 [Homo sapiens]
          Length = 403

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 56/244 (22%), Positives = 99/244 (40%), Gaps = 35/244 (14%)

Query: 229 SLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQ 288
           S++ F E++  P +PV+L    + W   +KW+LE ++     R    + G    D +   
Sbjct: 55  SVEEFVERYERPYKPVVLLNAQEGWSAQEKWTLERLKR--KYRNQKFKCGE---DNDGYS 109

Query: 289 TLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIP---ELKQDISIPDYCS---LGDGEEEE 342
             M +  +I +Y+ +   D         + + P   +L +D  +P + +        E+ 
Sbjct: 110 VKMKMKYYI-EYMESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKR 168

Query: 343 ITINAWF--GPQGTISPLHQDP----QQNFLVQVMGRKYIRLY---SPQE-------SGA 386
                WF  GP  + + +H DP      N LVQ  G K   L+   +P+E        G 
Sbjct: 169 RPPYRWFVMGPPRSGTGIHIDPLGTSAWNALVQ--GHKRWCLFPTSTPRELIKVTRDEGG 226

Query: 387 LYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLS 446
               +     N      + P     P+F     L  +  PGE +F+P  +WH V  LD +
Sbjct: 227 NQQDEAITWFNVIYPRTQLPTWP--PEFKP---LEILQKPGETVFVPGGWWHVVLNLDTT 281

Query: 447 FSVS 450
            +++
Sbjct: 282 IAIT 285


>gi|106879206 chromosome 14 open reading frame 169 [Homo sapiens]
          Length = 641

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 14/86 (16%)

Query: 359 HQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAP 418
           H D  + F++Q+ GRK  R+Y P+         T  L  TS  +    DL +       P
Sbjct: 340 HYDDIEAFVLQLEGRKLWRVYRPRV-------PTEELALTSSPNFSQDDLGE-------P 385

Query: 419 FLSCILSPGEILFIPVKYWHYVRALD 444
            L  +L PG++L+ P  + H     D
Sbjct: 386 VLQTVLEPGDLLYFPRGFIHQAECQD 411


>gi|4885323 G protein-coupled receptor 37 [Homo sapiens]
          Length = 613

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 37/106 (34%), Positives = 48/106 (45%), Gaps = 10/106 (9%)

Query: 7   SPGEGAEEGRGSEASGLKASAGHGTEPAGGGPMAGDT-HCPAEPLAREGTLWEALRALLP 65
           +PG     GRG+EAS      G  T P G     G     P+E L R      AL+  L 
Sbjct: 91  APGRDPAAGRGAEASA-AGPPGPPTRPPGPWRWKGARGQEPSETLGRGNP--TALQLFLQ 147

Query: 66  HSKEDLKLDLGEKV-----ERSVVTLLQRATELFYEGRRDECLQSS 106
            S+E+ K   G  +     E+SV T +  A++LFY  RR   LQ S
Sbjct: 148 ISEEEEKGPRGAGISGRSQEQSVKT-VPGASDLFYWPRRAGKLQGS 192


>gi|169205008 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 234

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 15/76 (19%)

Query: 8   PGEGAEEGRGSEASGLKASAGHGTEPAG--------------GGPMAGDTHCPAEPLARE 53
           PG   + GRG   SG++A  G G E AG               G    DT     P A  
Sbjct: 149 PGGSGDRGRGGRGSGVRAGPG-GAEAAGEGEAREGRGLAVSVSGTSVSDTATDTRPWAEA 207

Query: 54  GTLWEALRALLPHSKE 69
             L E  R    H KE
Sbjct: 208 DLLREWRRVAKQHLKE 223


>gi|169205607 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 234

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 15/76 (19%)

Query: 8   PGEGAEEGRGSEASGLKASAGHGTEPAG--------------GGPMAGDTHCPAEPLARE 53
           PG   + GRG   SG++A  G G E AG               G    DT     P A  
Sbjct: 149 PGGSGDRGRGGRGSGVRAGPG-GAEAAGEGEAREGRGLAVSVSGTSVSDTATDTRPWAEA 207

Query: 54  GTLWEALRALLPHSKE 69
             L E  R    H KE
Sbjct: 208 DLLREWRRVAKQHLKE 223


>gi|169204476 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 234

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 24/76 (31%), Positives = 27/76 (35%), Gaps = 15/76 (19%)

Query: 8   PGEGAEEGRGSEASGLKASAGHGTEPAG--------------GGPMAGDTHCPAEPLARE 53
           PG   + GRG   SG++A  G G E AG               G    DT     P A  
Sbjct: 149 PGGSGDRGRGGRGSGVRAGPG-GAEAAGEGEAREGRGLAVSVSGTSVSDTATDTRPWAEA 207

Query: 54  GTLWEALRALLPHSKE 69
             L E  R    H KE
Sbjct: 208 DLLREWRRVAKQHLKE 223


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 17/43 (39%), Positives = 18/43 (41%), Gaps = 5/43 (11%)

Query: 9   GEGAEEGRGSEASGLKASAGHGTEPAGGG-----PMAGDTHCP 46
           G G   GRG    G     G G  P+GGG       AGD  CP
Sbjct: 387 GRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCP 429


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 7/51 (13%)

Query: 10   EGAEEGRGSEASGLKASAGHGTEPAGGGPM-------AGDTHCPAEPLARE 53
            +G ++G  SEA  ++   G GT P+G G +       AGD   P E L  E
Sbjct: 2062 DGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSE 2112


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 18/48 (37%), Positives = 19/48 (39%)

Query: 2   SREKCSPGEGAEEGRGSEASGLKASAGHGTEPAGGGPMAGDTHCPAEP 49
           S    S G GA  G G    G   S G G+   GGG   G T   A P
Sbjct: 793 SGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGP 840


>gi|156416026 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 3   REKCSPGEGAEEGRGSEASGLKAS--AGHGTEPAGGGPMAGDTHCP 46
           R+  SPG     GRG EA  L  S  AG G E   GG +     CP
Sbjct: 607 RKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCP 652


>gi|156415998 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 3   REKCSPGEGAEEGRGSEASGLKAS--AGHGTEPAGGGPMAGDTHCP 46
           R+  SPG     GRG EA  L  S  AG G E   GG +     CP
Sbjct: 607 RKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCP 652


>gi|156415996 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 3   REKCSPGEGAEEGRGSEASGLKAS--AGHGTEPAGGGPMAGDTHCP 46
           R+  SPG     GRG EA  L  S  AG G E   GG +     CP
Sbjct: 607 RKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCP 652


>gi|223718074 hydroxysteroid (17-beta) dehydrogenase 1 [Homo
          sapiens]
          Length = 328

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 4/45 (8%)

Query: 50 LAREGTLWEALRALL--PHSKEDLKLDLGEKVERSVVTLLQRATE 92
          L  +G LWEA RAL   P S E L+LD+ +   +SV    +R TE
Sbjct: 40 LKTQGRLWEAARALACPPGSLETLQLDVRD--SKSVAAARERVTE 82


>gi|51944974 tumor suppressor candidate 1 [Homo sapiens]
          Length = 212

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 3/39 (7%)

Query: 3  REKCSPGEGAEEGRGSEASGLKASAGHGTEPAGGGPMAG 41
          R  C  G+GA +GRG   SG    A  G  P+GGG   G
Sbjct: 14 RGSCCGGDGAADGRGPGRSG---RARGGGSPSGGGGGVG 49


>gi|34787409 hypothetical protein LOC57148 [Homo sapiens]
          Length = 1494

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 11/55 (20%)

Query: 299  KYIVNEPR-----DVG--YLAQHQLF----DQIPELKQDISIPDYCSLGDGEEEE 342
            K  V EPR     DVG  Y  +H+ F    D+IP +K D+SIPD   +   E EE
Sbjct: 1003 KLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEE 1057


>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
          Length = 781

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 8/50 (16%)

Query: 14  EGRGSEASGLKASAGHGTEPAGGGPMAGDTHCPAEPLAREGTLWEALRAL 63
           EGRGS    L +S G G+E AGG P       PAEPL   G L+  L  L
Sbjct: 731 EGRGSSCGSL-SSLGSGSE-AGGAPG------PAEPLDDWGPLFRTLAEL 772


>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
          Length = 819

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 8/50 (16%)

Query: 14  EGRGSEASGLKASAGHGTEPAGGGPMAGDTHCPAEPLAREGTLWEALRAL 63
           EGRGS    L +S G G+E AGG P       PAEPL   G L+  L  L
Sbjct: 769 EGRGSSCGSL-SSLGSGSE-AGGAPG------PAEPLDDWGPLFRTLAEL 810


>gi|27436971 potassium voltage-gated channel, shaker-related
          subfamily, beta member 3 [Homo sapiens]
          Length = 404

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 22/56 (39%), Positives = 23/56 (41%), Gaps = 8/56 (14%)

Query: 6  CSPGEGAEEGRGSEASGLKASAGHGTEPAGG--GPMAGDTHCPAEPLAREGTLWEA 59
          C P  G   G G  A G     GHG  P GG  GP A     P  P A  G L E+
Sbjct: 22 CGPRPGPGGGNGGPAGG-----GHGNPPGGGGSGPKARAALVPRPP-APAGALRES 71


>gi|39930351 dynamin binding protein [Homo sapiens]
          Length = 1577

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 182 ILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPS 229
           I +  LP +R A    P +PCT  + + H L+ D  L+   P + RPS
Sbjct: 596 ITEQELPERRKALRPPPPRPCTPVSTSPH-LLVDQNLKPAPPLVVRPS 642


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,601,498
Number of Sequences: 37866
Number of extensions: 954315
Number of successful extensions: 3089
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3053
Number of HSP's gapped (non-prelim): 43
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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