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Search of human proteins with 223941912
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223941912 coiled-coil domain containing 135 [Homo sapiens]
(874 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223941912 coiled-coil domain containing 135 [Homo sapiens] 1788 0.0
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 48 5e-05
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 48 5e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 45 4e-04
gi|219803769 trichoplein [Homo sapiens] 44 5e-04
gi|14150056 trichoplein [Homo sapiens] 44 5e-04
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 42 0.002
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 40 0.009
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 39 0.016
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 39 0.016
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 39 0.016
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 39 0.016
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 39 0.021
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 39 0.021
gi|154354979 myosin X [Homo sapiens] 39 0.021
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.021
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 39 0.027
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 39 0.027
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 39 0.027
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 39 0.027
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 39 0.027
gi|71061468 centromere protein E [Homo sapiens] 39 0.027
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 39 0.027
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 37 0.061
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.061
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.061
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 37 0.061
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 37 0.061
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 37 0.061
gi|28195388 RAB11 family interacting protein 4 (class II) [Homo ... 37 0.080
>gi|223941912 coiled-coil domain containing 135 [Homo sapiens]
Length = 874
Score = 1788 bits (4632), Expect = 0.0
Identities = 874/874 (100%), Positives = 874/874 (100%)
Query: 1 MEVLREKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSEIQ 60
MEVLREKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSEIQ
Sbjct: 1 MEVLREKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSEIQ 60
Query: 61 ITVSAELPAFTKDTIDISKLPISYKTNTPKEEHLLQVADNFSRQYSHLCPDRVPLFLHPL 120
ITVSAELPAFTKDTIDISKLPISYKTNTPKEEHLLQVADNFSRQYSHLCPDRVPLFLHPL
Sbjct: 61 ITVSAELPAFTKDTIDISKLPISYKTNTPKEEHLLQVADNFSRQYSHLCPDRVPLFLHPL 120
Query: 121 NECEVPKFVSTTLRPTLMPYPELYNWDSCAQFVSDFLTMVPLPDPLKPPSHLYSSTTVLK 180
NECEVPKFVSTTLRPTLMPYPELYNWDSCAQFVSDFLTMVPLPDPLKPPSHLYSSTTVLK
Sbjct: 121 NECEVPKFVSTTLRPTLMPYPELYNWDSCAQFVSDFLTMVPLPDPLKPPSHLYSSTTVLK 180
Query: 181 YQKGNCFDFSTLLCSMLIGSGYDAYCVNGYGSLDLCHMDLTREVCPLTVKPKETIKKEEK 240
YQKGNCFDFSTLLCSMLIGSGYDAYCVNGYGSLDLCHMDLTREVCPLTVKPKETIKKEEK
Sbjct: 181 YQKGNCFDFSTLLCSMLIGSGYDAYCVNGYGSLDLCHMDLTREVCPLTVKPKETIKKEEK 240
Query: 241 VLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEKAKPDALHGLR 300
VLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEKAKPDALHGLR
Sbjct: 241 VLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEKAKPDALHGLR 300
Query: 301 VHSWVLVLSGKREVPENFFIDPFTGHSYSTQDEHFLGIESLWNHKNYWINMQDCWNCCKD 360
VHSWVLVLSGKREVPENFFIDPFTGHSYSTQDEHFLGIESLWNHKNYWINMQDCWNCCKD
Sbjct: 301 VHSWVLVLSGKREVPENFFIDPFTGHSYSTQDEHFLGIESLWNHKNYWINMQDCWNCCKD 360
Query: 361 LIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDDVENLGKEDEDKSFDMPHSWVEQ 420
LIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDDVENLGKEDEDKSFDMPHSWVEQ
Sbjct: 361 LIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDDVENLGKEDEDKSFDMPHSWVEQ 420
Query: 421 IEISPEAFETRCPNGKKVIQYKRAKLEKWAPYLNSNGLVSRLTTYEDLQCTNILEIKEWY 480
IEISPEAFETRCPNGKKVIQYKRAKLEKWAPYLNSNGLVSRLTTYEDLQCTNILEIKEWY
Sbjct: 421 IEISPEAFETRCPNGKKVIQYKRAKLEKWAPYLNSNGLVSRLTTYEDLQCTNILEIKEWY 480
Query: 481 QNREDMLELKHINKTTDLKTDYFKPGHPQALRVHSYKSMQPEMDRVIEFYETARVDGLMK 540
QNREDMLELKHINKTTDLKTDYFKPGHPQALRVHSYKSMQPEMDRVIEFYETARVDGLMK
Sbjct: 481 QNREDMLELKHINKTTDLKTDYFKPGHPQALRVHSYKSMQPEMDRVIEFYETARVDGLMK 540
Query: 541 REETPRTMTEYYQGRPDFLSYRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPAKPA 600
REETPRTMTEYYQGRPDFLSYRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPAKPA
Sbjct: 541 REETPRTMTEYYQGRPDFLSYRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPAKPA 600
Query: 601 EEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVE 660
EEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVE
Sbjct: 601 EEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVE 660
Query: 661 PMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTK 720
PMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTK
Sbjct: 661 PMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTK 720
Query: 721 RNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDF 780
RNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDF
Sbjct: 721 RNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDF 780
Query: 781 KQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQ 840
KQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQ
Sbjct: 781 KQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQ 840
Query: 841 RLNRHKELAPLKYLALEEKLYKDPRLGELQKIFA 874
RLNRHKELAPLKYLALEEKLYKDPRLGELQKIFA
Sbjct: 841 RLNRHKELAPLKYLALEEKLYKDPRLGELQKIFA 874
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 47.8 bits (112), Expect = 5e-05
Identities = 117/547 (21%), Positives = 211/547 (38%), Gaps = 78/547 (14%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQ---EIRAQEKKRLREEEERLM 286
KP+E +KE+ K IK P + E E+E K++ EI+ + K+ EEE+
Sbjct: 438 KPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKA- 496
Query: 287 EAEKAKPDALHGLRVHSWVLVLSGKREVPENFFIDPFTGHSYSTQDEHFLG---IESLWN 343
A+KAKP A + W +V +G V FF +P T S + + +G ++ +
Sbjct: 497 -AQKAKPVATAPIPGTPWCVVWTGDERV---FFYNPTTRLSMWDRPDDLIGRADVDKIIQ 552
Query: 344 HKNYWINMQDCWNCCKDLIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDDVE-NL 402
+ M++ L +W++ + K + L EE IN+++ V+
Sbjct: 553 EPPHKKGMEELKKLRHPTPTMLSIQ-KWQFS-MSAIKEEQELMEE----INEDEPVKAKK 606
Query: 403 GKEDEDKSFDMPHSWVEQIEISPEAFETRCPNGKKVIQYKRAKLEK-------WAPYLNS 455
K D++K D + EI P ++ Q+K LE+ W L+
Sbjct: 607 RKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHK 666
Query: 456 NGLVSRLTTYEDLQCTNILEIKEWYQNREDMLELKHINKTTDLKTDY------------- 502
R + + + ++ + R + + NK K D+
Sbjct: 667 IVFDPRYLLLNPKERKQVFD--QYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRA 724
Query: 503 ----FKPGHPQALRVHSYKSMQPEMDRVIEFYETARVDGLMKREETPRTMTEYYQGRPDF 558
F H + R + + M+ EF AR K +E +T E + + DF
Sbjct: 725 TFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAAR----KKEKEDSKTRGE--KIKSDF 778
Query: 559 ---LSYRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPAKPAEEDVAERV------F 609
LS H R K+ ES+PR + + K E +A+ +
Sbjct: 779 FELLSNHHLDSQSRWSKVK-DKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKE 837
Query: 610 LVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNK--------IIMTPDMCISFEV-- 659
L + RI+ RE + ++ E + + + + +K + DM S +V
Sbjct: 838 LERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSW 897
Query: 660 EPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVL-----EILKLREEEEAAHTLTI 714
T + +++E+ L+REEK +++ +E L E + +E +A TLT
Sbjct: 898 SDTRRTLRKDHRWESGSLLEREEK---EKLFNEHIEALTKKKREHFRQLLDETSAITLTS 954
Query: 715 SIYDTKR 721
+ + K+
Sbjct: 955 TWKEVKK 961
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 47.8 bits (112), Expect = 5e-05
Identities = 117/547 (21%), Positives = 211/547 (38%), Gaps = 78/547 (14%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQ---EIRAQEKKRLREEEERLM 286
KP+E +KE+ K IK P + E E+E K++ EI+ + K+ EEE+
Sbjct: 459 KPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKA- 517
Query: 287 EAEKAKPDALHGLRVHSWVLVLSGKREVPENFFIDPFTGHSYSTQDEHFLG---IESLWN 343
A+KAKP A + W +V +G V FF +P T S + + +G ++ +
Sbjct: 518 -AQKAKPVATAPIPGTPWCVVWTGDERV---FFYNPTTRLSMWDRPDDLIGRADVDKIIQ 573
Query: 344 HKNYWINMQDCWNCCKDLIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDDVE-NL 402
+ M++ L +W++ + K + L EE IN+++ V+
Sbjct: 574 EPPHKKGMEELKKLRHPTPTMLSIQ-KWQFS-MSAIKEEQELMEE----INEDEPVKAKK 627
Query: 403 GKEDEDKSFDMPHSWVEQIEISPEAFETRCPNGKKVIQYKRAKLEK-------WAPYLNS 455
K D++K D + EI P ++ Q+K LE+ W L+
Sbjct: 628 RKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHK 687
Query: 456 NGLVSRLTTYEDLQCTNILEIKEWYQNREDMLELKHINKTTDLKTDY------------- 502
R + + + ++ + R + + NK K D+
Sbjct: 688 IVFDPRYLLLNPKERKQVFD--QYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRA 745
Query: 503 ----FKPGHPQALRVHSYKSMQPEMDRVIEFYETARVDGLMKREETPRTMTEYYQGRPDF 558
F H + R + + M+ EF AR K +E +T E + + DF
Sbjct: 746 TFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAAR----KKEKEDSKTRGE--KIKSDF 799
Query: 559 ---LSYRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPAKPAEEDVAERV------F 609
LS H R K+ ES+PR + + K E +A+ +
Sbjct: 800 FELLSNHHLDSQSRWSKVK-DKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKE 858
Query: 610 LVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNK--------IIMTPDMCISFEV-- 659
L + RI+ RE + ++ E + + + + +K + DM S +V
Sbjct: 859 LERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSW 918
Query: 660 EPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVL-----EILKLREEEEAAHTLTI 714
T + +++E+ L+REEK +++ +E L E + +E +A TLT
Sbjct: 919 SDTRRTLRKDHRWESGSLLEREEK---EKLFNEHIEALTKKKREHFRQLLDETSAITLTS 975
Query: 715 SIYDTKR 721
+ + K+
Sbjct: 976 TWKEVKK 982
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 44.7 bits (104), Expect = 4e-04
Identities = 57/257 (22%), Positives = 122/257 (47%), Gaps = 18/257 (7%)
Query: 601 EEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVE 660
+EDV ER+ + ++L+ R+ + +++ + E + NKI +
Sbjct: 47 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTS 106
Query: 661 PMEHTKKLLYQYEAMM--HLKREEKLSRH--QVWESELEVLEIL-KLREEEEAAHTLTIS 715
++ +++ Q ++ + EE+LS+H E E+E+ +I KL+E+EE TL
Sbjct: 107 LNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQ 166
Query: 716 IYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGE-KLTCWQAVRLKD 774
+ + + ++ E E +M ++ L++ E ++++ AQL + + Q VR KD
Sbjct: 167 LTQAQAEQPAQSSTEMEEFVMMKQQLQEKE---EFISTLQAQLSQTQAEQAAQQVVREKD 223
Query: 775 -------ECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSY 827
D +L+ +A+ ++ +++ + LQ+K + ++E+ V + DL
Sbjct: 224 ARFETQVRLHEDELLQLVTQAD-VETEMQQKLRVLQRKLEEHEESLVG-RAQVVDLLQQE 281
Query: 828 CSQAMFRIRILEQRLNR 844
+ A R +IL Q+L +
Sbjct: 282 LTAAEQRNQILSQQLQQ 298
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 44.3 bits (103), Expect = 5e-04
Identities = 46/144 (31%), Positives = 71/144 (49%), Gaps = 22/144 (15%)
Query: 666 KKLLYQYEAMMHLK-REEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKR--N 722
++LLY++ + K RE +L HQ V+ ++++EE+ T + KR N
Sbjct: 136 EQLLYEHWKKNNPKLREMELDLHQK-----HVVNSWEMQKEEKKQQEATAE-QENKRYEN 189
Query: 723 EKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQ 782
E + REA+ERM EE RQ+E +L A L Q KL +A +LK E
Sbjct: 190 EYERARREALERMKAEEERRQLEDKLQ--AEALLQQMEELKLKEVEATKLKKE------- 240
Query: 783 RLINKANLIQARFEKETQELQKKQ 806
+ NL++ R+E E E ++KQ
Sbjct: 241 ----QENLLKQRWELERLEEERKQ 260
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 44.3 bits (103), Expect = 5e-04
Identities = 46/144 (31%), Positives = 71/144 (49%), Gaps = 22/144 (15%)
Query: 666 KKLLYQYEAMMHLK-REEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKR--N 722
++LLY++ + K RE +L HQ V+ ++++EE+ T + KR N
Sbjct: 136 EQLLYEHWKKNNPKLREMELDLHQK-----HVVNSWEMQKEEKKQQEATAE-QENKRYEN 189
Query: 723 EKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQ 782
E + REA+ERM EE RQ+E +L A L Q KL +A +LK E
Sbjct: 190 EYERARREALERMKAEEERRQLEDKLQ--AEALLQQMEELKLKEVEATKLKKE------- 240
Query: 783 RLINKANLIQARFEKETQELQKKQ 806
+ NL++ R+E E E ++KQ
Sbjct: 241 ----QENLLKQRWELERLEEERKQ 260
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 42.4 bits (98), Expect = 0.002
Identities = 60/232 (25%), Positives = 107/232 (46%), Gaps = 29/232 (12%)
Query: 660 EPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEIL---------KLREEEEAAH 710
EP K+ + HL++E + Q+ ++E+E ++L +LRE+EE H
Sbjct: 151 EPPAGPSKVEQLQDETNHLRKELESVGRQL-QAEVENNQMLSLLNRRQEERLREQEERLH 209
Query: 711 TLTISIYDTKRN--EKSKEYREAMERMM-HEEHLRQVETQLDYLAPFLAQLPPGEKLTCW 767
+++ + E+ + E ER+ EE LR+ E +L L + E+ C
Sbjct: 210 EQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCE---QEERLCE 266
Query: 768 QAVRLKDECLSDFKQRLINKAN--LIQARFEKETQELQKKQQWYQE-----NQVTLTPED 820
Q RL ++ ++RL+ + L Q R ++E + L ++++ E Q L +D
Sbjct: 267 QEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQD 326
Query: 821 EDLYLSYCSQAMFRIRILE--QRLNRHKELAPLKYLALEEKLYK---DPRLG 867
E L+ + + R+R LE + L R +EL + L E LY+ +PR G
Sbjct: 327 ERLWQQETLRELERLRELERLRELERLRELERMLELGW-EALYEQRAEPRSG 377
Score = 34.7 bits (78), Expect = 0.40
Identities = 15/32 (46%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ + +Q+E ++++RLRE+EERL E E+
Sbjct: 217 EQEERLCEQEERLCEQEERLREQEERLREQEE 248
Score = 34.3 bits (77), Expect = 0.52
Identities = 14/32 (43%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ +++Q+E ++++RL E+EERL E E+
Sbjct: 231 EQEERLREQEERLREQEERLHEQEERLCEQEE 262
Score = 33.9 bits (76), Expect = 0.68
Identities = 15/32 (46%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ + +Q+E ++++RLRE+EERL E E+
Sbjct: 224 EQEERLCEQEERLREQEERLREQEERLHEQEE 255
Score = 33.9 bits (76), Expect = 0.68
Identities = 15/32 (46%), Positives = 24/32 (75%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ + +Q+E ++++RL E+EERL E EK
Sbjct: 245 EQEERLHEQEERLCEQEERLCEQEERLCEQEK 276
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/32 (43%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ +++Q+E ++++RL E+EERL E E+
Sbjct: 238 EQEERLREQEERLHEQEERLCEQEERLCEQEE 269
Score = 32.3 bits (72), Expect = 2.0
Identities = 14/32 (43%), Positives = 24/32 (75%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ + +Q+E ++++RL E+EERL E E+
Sbjct: 210 EQEERLHEQEERLCEQEERLCEQEERLREQEE 241
Score = 32.0 bits (71), Expect = 2.6
Identities = 13/31 (41%), Positives = 24/31 (77%)
Query: 260 QEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
QE+ +++Q+E ++++RL E+EERL E E+
Sbjct: 197 QEERLREQEERLHEQEERLHEQEERLCEQEE 227
Score = 31.6 bits (70), Expect = 3.4
Identities = 14/32 (43%), Positives = 24/32 (75%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ + +Q+E ++++RL E+EERL E E+
Sbjct: 203 EQEERLHEQEERLHEQEERLCEQEERLCEQEE 234
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 40.0 bits (92), Expect = 0.009
Identities = 54/218 (24%), Positives = 95/218 (43%), Gaps = 49/218 (22%)
Query: 655 ISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTI 714
I ++E +KLL + L E K + ++ E ELEVL+ HT +I
Sbjct: 284 IKIKIELKHAQQKLLDSTKMCSSLTAEYKHCQQKIKELELEVLK-----------HTQSI 332
Query: 715 SIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKD 774
++ N + K +E + EE + ++ +L++ V L D
Sbjct: 333 K---SQNNLQEKLVQEKSKVADAEEKILDLQRKLEHA----------------HKVCLTD 373
Query: 775 ECLSDFKQRL---INKANLIQARFEKETQELQKKQQWYQEN------QVTLTPEDEDLYL 825
C+S+ KQ+L I +A +A+ +++ QE Q+K++ +N QV + E+L
Sbjct: 374 TCISE-KQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLE 432
Query: 826 SYCSQAMFRIRILEQRLNRHKELAPLKYLALEEKLYKD 863
CSQ RI+ ++ A LK L E++ Y +
Sbjct: 433 MTCSQQQSRIQ---------QQEALLKQLENEKRKYDE 461
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 39.3 bits (90), Expect = 0.016
Identities = 57/266 (21%), Positives = 115/266 (43%), Gaps = 65/266 (24%)
Query: 601 EEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVE 660
EE + E+ + E+ ++R R++ + K E +RR E E
Sbjct: 320 EEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQE--------------------E 356
Query: 661 PMEHTKKLLYQYEAMMHLKREEKLSRHQ--VWESELEVLEILKLREEEEAAHTLTISIYD 718
M ++ + + E MM ++EEK+ R + +WE E K+RE EE H
Sbjct: 357 MMWEKEEKMRRQEEMMW-EKEEKMRRQEEMMWEKEE------KIRELEEKMH-------- 401
Query: 719 TKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLS 778
+ ++ RE E+ EE +R+ E + + A Q + +R ++E +
Sbjct: 402 -----EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ---------EEKIREQEEKIR 447
Query: 779 DFKQRLINKANLI--QARFEKETQELQKKQQWYQENQVTLTPEDEDLY--LSYCSQAMFR 834
+ ++++ + I Q + +E + ++++ W QE ++ E E+++ + +
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI---HEQEEIWRQKEKMHEQEEK 504
Query: 835 IRILEQRLNRHKELAPLKYLALEEKL 860
IR E+++ R +E K EEK+
Sbjct: 505 IRKQEEKVWRQEE----KIREQEEKI 526
Score = 35.8 bits (81), Expect = 0.18
Identities = 15/55 (27%), Positives = 38/55 (69%), Gaps = 2/55 (3%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
K+EEK+ ++ I+ + EQE+++++Q+E+ ++++++ E+EE++ E E+
Sbjct: 609 KQEEKIREQEEKIQEQEEKIR--EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
Score = 34.7 bits (78), Expect = 0.40
Identities = 47/262 (17%), Positives = 119/262 (45%), Gaps = 23/262 (8%)
Query: 613 EERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQY 672
EE+I + RE+ + E R+ E + +I + E + + +K+ Q
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 673 EAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRNE-------KS 725
E + + + + ++W E ++ E ++ EEE H + KR E +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 726 KEYREAMERM-MHEEHLRQVETQLDYLAPFLAQLPPGEKL-TCWQAVRLKDECLSDFKQR 783
++ RE E++ EE +R+ E + + + EK+ + ++ ++E + + +++
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK--QEEKIREQEEKIQEQEEKIREQEEK 634
Query: 784 LINKANLIQARFEK---ETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQ 840
+ + + Q + EK + +++ ++++ QE + T+ ++E + + +IR E+
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI-----REQEKKIREQEE 689
Query: 841 RLNRHKELAPLKYLALEEKLYK 862
++ +E+ + EEK+++
Sbjct: 690 KIREQEEMMQEQ----EEKMWE 707
Score = 34.7 bits (78), Expect = 0.40
Identities = 23/62 (37%), Positives = 40/62 (64%), Gaps = 9/62 (14%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQE-IRAQEKK------RLREEEERLMEA 288
++EEKV ++ I+ + R EQE+++ KQ+E IR QE+K ++RE+EE++ E
Sbjct: 581 EQEEKVWRQEEKIREQEE--KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 289 EK 290
E+
Sbjct: 639 EE 640
Score = 34.3 bits (77), Expect = 0.52
Identities = 16/61 (26%), Positives = 43/61 (70%), Gaps = 1/61 (1%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEKA 291
+E ++++E+++ +K K R +E+E+++++Q+E+ ++++++RE EE++ E EK
Sbjct: 348 EEKMRRQEEMMWEKEE-KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 406
Query: 292 K 292
+
Sbjct: 407 R 407
Score = 33.9 bits (76), Expect = 0.68
Identities = 16/59 (27%), Positives = 39/59 (66%), Gaps = 3/59 (5%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+E ++EEK+ ++ + + EQE++++KQ+E ++++++RE+EE++ E E+
Sbjct: 476 EEMWRQEEKIHEQEEIWRQKEKM---HEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531
Score = 33.9 bits (76), Expect = 0.68
Identities = 18/55 (32%), Positives = 35/55 (63%), Gaps = 9/55 (16%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
K+EEKV ++ I+ EQE+++++Q+E ++++++RE+EE E EK
Sbjct: 507 KQEEKVWRQEEKIR---------EQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Score = 33.5 bits (75), Expect = 0.88
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
EK+ E+EE RE+ E W + EK+ ++R+EE +QE + E+K+ E
Sbjct: 437 EKIREQEEKIREQ--EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Score = 33.5 bits (75), Expect = 0.88
Identities = 14/55 (25%), Positives = 37/55 (67%), Gaps = 9/55 (16%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ I+ EQE+++++Q+E+ ++++++ E+EE++ E E+
Sbjct: 672 RQEEKIREQEKKIR---------EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717
Score = 33.1 bits (74), Expect = 1.2
Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 5/74 (6%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQE-IRAQEKKRLREEEERLMEAEK 290
+E ++EEK+ ++ K + QE+++++Q+E IR QEKK R +EE++ E EK
Sbjct: 410 EEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQEEKIREQEKKMWR-QEEKIHEQEK 465
Query: 291 AKPDALHGLRVHSW 304
+ + + W
Sbjct: 466 IREEEKRQEQEEMW 479
Score = 32.7 bits (73), Expect = 1.5
Identities = 30/156 (19%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
Query: 663 EHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRN 722
E K+ Q E + + + + ++W E ++ E K+REEE+ + + K +
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
Query: 723 EKSKEYREAMERMMHEEHLRQVE----TQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLS 778
E+ + +R+ + EE +R+ E Q + + ++ E+ Q +++++
Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ--- 543
Query: 779 DFKQRLINKANLIQARFEKETQELQKKQQWYQENQV 814
+ R K + + +E+E ++ Q+ + W QE ++
Sbjct: 544 EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579
Score = 32.3 bits (72), Expect = 2.0
Identities = 14/60 (23%), Positives = 39/60 (65%), Gaps = 5/60 (8%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSR-----FEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ I+ + R +E+E+++++Q+E+ ++++++R +EE + E E+
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Score = 32.3 bits (72), Expect = 2.0
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 15/61 (24%)
Query: 9 EEEEEAEREEAAEWAE-----------WARMEKMMRPVEVRKEEITLKQETLRDLEKKLS 57
E+EE+ R+E W + W + EKM R E+ E K+E +R+LE+K+
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE----KEEKIRELEEKMH 401
Query: 58 E 58
E
Sbjct: 402 E 402
Score = 32.0 bits (71), Expect = 2.6
Identities = 14/53 (26%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Query: 238 EEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EEK+ ++ I+ + EQE+++++Q+E+ ++++++R +EE + E E+
Sbjct: 313 EEKIQEQEEKIREQEEKIR--EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Score = 32.0 bits (71), Expect = 2.6
Identities = 20/61 (32%), Positives = 37/61 (60%), Gaps = 11/61 (18%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
K ++ ++EE + K+ I+ E E+++ +Q++IR QE+K R+EEE++ E E
Sbjct: 375 KEEKMRRQEEMMWEKEEKIR---------ELEEKMHEQEKIREQEEK--RQEEEKIREQE 423
Query: 290 K 290
K
Sbjct: 424 K 424
Score = 31.6 bits (70), Expect = 3.4
Identities = 16/70 (22%), Positives = 46/70 (65%), Gaps = 3/70 (4%)
Query: 222 REVCPLTVKPKETI-KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLRE 280
RE +T + +E + ++EEK+ ++ ++ + + + QE+++++Q++ ++++++RE
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE--TMWRQEEKIREQEKKIREQEEKIRE 693
Query: 281 EEERLMEAEK 290
+EE + E E+
Sbjct: 694 QEEMMQEQEE 703
Score = 31.6 bits (70), Expect = 3.4
Identities = 14/58 (24%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
K+ ++EEK+ ++ ++ + +EQE+++ +Q+E ++++++R +EE++ E E
Sbjct: 682 KKIREQEEKIREQEEMMQEQEE--KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Score = 31.2 bits (69), Expect = 4.4
Identities = 15/59 (25%), Positives = 42/59 (71%), Gaps = 3/59 (5%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+E ++++E+++ +K + R+L + +++++++Q+E R QE++++RE+E+R + K
Sbjct: 376 EEKMRRQEEMMWEKE--EKIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQEQEAK 431
Score = 31.2 bits (69), Expect = 4.4
Identities = 17/59 (28%), Positives = 37/59 (62%), Gaps = 6/59 (10%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREE----EERLMEAEK 290
++EEK+ ++ I+ + QE+++ +Q++IR +EK++ +EE EE++ E E+
Sbjct: 434 RQEEKIREQEEKIREQEK--KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Score = 31.2 bits (69), Expect = 4.4
Identities = 16/35 (45%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 259 EQEQEVKKQQE-IRAQEKKRLREEEERLMEAEKAK 292
EQE++V +Q+E IR QE+KR +EE+ + EK +
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Score = 30.8 bits (68), Expect = 5.7
Identities = 16/61 (26%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEKA 291
+E ++++E+++ +K K R +E+E+++++ +E + E++++RE+EE+ E EK
Sbjct: 362 EEKMRRQEEMMWEKEE-KMRRQEEMMWEKEEKIRELEE-KMHEQEKIREQEEKRQEEEKI 419
Query: 292 K 292
+
Sbjct: 420 R 420
Score = 30.8 bits (68), Expect = 5.7
Identities = 11/50 (22%), Positives = 31/50 (62%)
Query: 9 EEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
E+EE+ + +E W + ++ + + + ++E+I ++E +++ E+K+ E
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707
Score = 30.8 bits (68), Expect = 5.7
Identities = 11/29 (37%), Positives = 24/29 (82%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLME 287
EQE+++++Q+E +++ RLR++EE++ E
Sbjct: 721 EQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 30.4 bits (67), Expect = 7.5
Identities = 12/54 (22%), Positives = 31/54 (57%)
Query: 5 REKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
+E++ +EE E+ W + +M + + ++E++ ++E +R+ E+K+ E
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Score = 30.4 bits (67), Expect = 7.5
Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 14/68 (20%)
Query: 5 REKVEEEEEAEREEAAEWAE-----------WARMEKMMRPVEVRKEE---ITLKQETLR 50
+EK+ EEE+ + +E W + W + EK+ E R+E+ + ++E +R
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 51 DLEKKLSE 58
+ E+K+ E
Sbjct: 616 EQEEKIQE 623
Score = 30.4 bits (67), Expect = 7.5
Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 6/53 (11%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
EK+ E+EE +E+ E W + EK + ++E+I ++E +R+ E+K+ E
Sbjct: 591 EKIREQEEKRQEQ--EEKMWKQEEK----IREQEEKIQEQEEKIREQEEKIRE 637
Score = 30.4 bits (67), Expect = 7.5
Identities = 12/55 (21%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++E+K+ ++ I+ ++ EQE+++ +Q+E +++++++E+EE++ E+
Sbjct: 679 EQEKKIREQEEKIREQEEMMQ--EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Score = 30.0 bits (66), Expect = 9.8
Identities = 15/35 (42%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 259 EQEQEVKKQQE-IRAQEKKRLREEEERLMEAEKAK 292
EQE+++++Q+E IR QE+K R+EE + EK +
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Score = 30.0 bits (66), Expect = 9.8
Identities = 14/61 (22%), Positives = 38/61 (62%), Gaps = 3/61 (4%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
+ +E + ++EK+ ++ K + QE+++++Q+E ++++++RE+EE+ E E
Sbjct: 548 REEEKMHEQEKIWEEE---KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE 604
Query: 290 K 290
+
Sbjct: 605 E 605
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/56 (35%), Positives = 39/56 (69%), Gaps = 4/56 (7%)
Query: 236 KKEEKVLPKKYTIKPPRD-LCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EE++ ++ ++ + LC EQE+ +++Q+E ++++RLRE+EERL E EK
Sbjct: 280 EQEERLCEQEERLREQEERLC---EQEERLREQEERLCEQEERLREQEERLCEQEK 332
Score = 38.5 bits (88), Expect = 0.027
Identities = 18/44 (40%), Positives = 30/44 (68%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEKAKPDALHGLRVH 302
EQE+ +++Q+E ++++RLRE+EERL E E+ + LR H
Sbjct: 210 EQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREH 253
Score = 36.2 bits (82), Expect = 0.14
Identities = 58/268 (21%), Positives = 107/268 (39%), Gaps = 48/268 (17%)
Query: 578 AESNPRPIVKITERFFRNPAKPAEEDVAERVFLVAEERIQLRYHCREDHITASKREFLRR 637
AE ++ + R + EE + E+ + E+ +L C ++ + E LR
Sbjct: 182 AEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERL---CEQEERLREQEERLRE 238
Query: 638 TEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLK---REEKLSRHQVWESEL 694
E + E EH ++L Q E + + RE++ H+ E
Sbjct: 239 QE------------ERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLC 286
Query: 695 EVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPF 754
E E L+ +EE + + + E+ + RE ER+ +E L E L+ +
Sbjct: 287 EQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEV--- 343
Query: 755 LAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQV 814
EKL L+ E + ++RL+ + L++ E +EL ++++
Sbjct: 344 -------EKL-------LEQERRQEEQERLLERERLLE-----EVEELLEQER------- 377
Query: 815 TLTPEDEDLYLSYCSQAMFRIRILEQRL 842
L +DE L+ Q + R+R LE+ L
Sbjct: 378 -LRQQDERLWQQETLQELERLRELERML 404
Score = 35.8 bits (81), Expect = 0.18
Identities = 15/32 (46%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ +++Q+E ++++RLRE EERL E E+
Sbjct: 231 EQEERLREQEERLCEQEERLREHEERLCEQEE 262
Score = 35.4 bits (80), Expect = 0.23
Identities = 15/32 (46%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ + +Q+E ++++RLRE+EERL E E+
Sbjct: 273 EQEERLHEQEERLCEQEERLREQEERLCEQEE 304
Score = 34.3 bits (77), Expect = 0.52
Identities = 14/31 (45%), Positives = 25/31 (80%)
Query: 260 QEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
QE+ +++Q+E ++++RLRE+EERL E E+
Sbjct: 197 QEERLREQEERLREQEERLREQEERLCEQEE 227
Score = 33.5 bits (75), Expect = 0.88
Identities = 18/56 (32%), Positives = 38/56 (67%), Gaps = 4/56 (7%)
Query: 236 KKEEKVLPKKYTIKPPRD-LCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EE++ ++ ++ + LC EQE+ +++Q+E ++++RL E+EERL E E+
Sbjct: 203 EQEERLREQEERLREQEERLC---EQEERLREQEERLREQEERLCEQEERLREHEE 255
Score = 33.1 bits (74), Expect = 1.2
Identities = 18/56 (32%), Positives = 37/56 (66%), Gaps = 4/56 (7%)
Query: 236 KKEEKVLPKKYTIKPPRD-LCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EE++ ++ ++ + LC EQE+ + +Q+E ++++RL E+EERL E E+
Sbjct: 238 EQEERLCEQEERLREHEERLC---EQEERLCEQEERLREQEERLHEQEERLCEQEE 290
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/32 (43%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+ +++Q+E ++++RL E+EERL E E+
Sbjct: 266 EQEERLREQEERLHEQEERLCEQEERLREQEE 297
Score = 32.3 bits (72), Expect = 2.0
Identities = 18/63 (28%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQ--EQEVKKQQEIRAQEKKRLREEEERLMEAE 289
+E ++++E+ L ++ + L E+ EQE +++++ R E++RL EE E L+E E
Sbjct: 317 EERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQE 376
Query: 290 KAK 292
+ +
Sbjct: 377 RLR 379
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/65 (30%), Positives = 36/65 (55%)
Query: 228 TVKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLME 287
TV KE K + K+ KK K P D R E ++ K+ +E + +++++++ EEE +
Sbjct: 30 TVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKK 89
Query: 288 AEKAK 292
E+ K
Sbjct: 90 EEEEK 94
Score = 33.1 bits (74), Expect = 1.2
Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEI--RAQEKKRLREEEERLMEAEKAKP 293
KKE+K KK K + S+ ++E+E KK QE + QE++ R++EE K K
Sbjct: 66 KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKE 125
Query: 294 DALHGLRVHSW 304
+++ L +W
Sbjct: 126 ESIQ-LHQEAW 135
Score = 31.2 bits (69), Expect = 4.4
Identities = 18/56 (32%), Positives = 30/56 (53%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERL 285
K +E +K EE+ K+ K R +QE++ K+QQE A + + +EE +L
Sbjct: 75 KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQL 130
Score = 30.4 bits (67), Expect = 7.5
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 17/69 (24%)
Query: 229 VKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEA 288
VK +E KK+E+ KK+ QE+E KKQ+E + KR +EEE
Sbjct: 80 VKAEEESKKKEEEEKKKH-------------QEEERKKQEE----QAKRQQEEEAAAQMK 122
Query: 289 EKAKPDALH 297
EK + LH
Sbjct: 123 EKEESIQLH 131
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/65 (30%), Positives = 36/65 (55%)
Query: 228 TVKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLME 287
TV KE K + K+ KK K P D R E ++ K+ +E + +++++++ EEE +
Sbjct: 30 TVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKK 89
Query: 288 AEKAK 292
E+ K
Sbjct: 90 EEEEK 94
Score = 33.1 bits (74), Expect = 1.2
Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEI--RAQEKKRLREEEERLMEAEKAKP 293
KKE+K KK K + S+ ++E+E KK QE + QE++ R++EE K K
Sbjct: 66 KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKE 125
Query: 294 DALHGLRVHSW 304
+++ L +W
Sbjct: 126 ESIQ-LHQEAW 135
Score = 31.2 bits (69), Expect = 4.4
Identities = 18/56 (32%), Positives = 30/56 (53%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERL 285
K +E +K EE+ K+ K R +QE++ K+QQE A + + +EE +L
Sbjct: 75 KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQL 130
Score = 30.4 bits (67), Expect = 7.5
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 17/69 (24%)
Query: 229 VKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEA 288
VK +E KK+E+ KK+ QE+E KKQ+E + KR +EEE
Sbjct: 80 VKAEEESKKKEEEEKKKH-------------QEEERKKQEE----QAKRQQEEEAAAQMK 122
Query: 289 EKAKPDALH 297
EK + LH
Sbjct: 123 EKEESIQLH 131
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 38.9 bits (89), Expect = 0.021
Identities = 44/236 (18%), Positives = 106/236 (44%), Gaps = 35/236 (14%)
Query: 613 EERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQY 672
EE++ + RE + E +R E + + + I + E + ++++ +
Sbjct: 350 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ 409
Query: 673 EAMMHLKREEKLSRHQVWESELEVLEIL-KLREEEEAAHTLTISIYDTKRNEKSKEYREA 731
E M ++EEK+ WE E E+ E K+R +EE K E+ K+ RE
Sbjct: 410 EEKMG-EQEEKM-----WEQEEEMQEQEEKMRRQEE------------KIREQEKKIREQ 451
Query: 732 MERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLI 791
E++ +E + Q + + ++ E C Q +++++ + +R K
Sbjct: 452 EEKIREQEEMMQEQEE---------KMGEQEGKMCEQEAKMQEQ--EEKMRRQEEKIREQ 500
Query: 792 QARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQRLNRHKE 847
+ + ++ ++++++++ QE + + ++E + C Q +++ E+++ R +E
Sbjct: 501 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKM----CEQEE-KMQEQEEKMRRQEE 551
Score = 35.8 bits (81), Expect = 0.18
Identities = 39/188 (20%), Positives = 83/188 (44%), Gaps = 41/188 (21%)
Query: 663 EHTKKLLYQYEAMMHLKREEKLSRHQ--VWESELEVLEILKLREEEEAAHTLTISIYDTK 720
E +K+ Q E M ++EEK+ R + +WE E K+RE EE H
Sbjct: 313 EQEEKMRRQEEMMW--EKEEKMRRQEEMMWEKEE------KIRELEEKMH---------- 354
Query: 721 RNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDF 780
+ ++ RE E+ EE +R+ E + + ++ W+ ++E + +
Sbjct: 355 ---EQEKIREQEEKRQEEEKIREQEKRQE------------QEAKMWR----QEEKIREQ 395
Query: 781 KQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQ 840
++++ + ++Q + EK + Q+++ W QE ++ E + +IR E+
Sbjct: 396 EEKIREQEEMMQEQEEKMGE--QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE 453
Query: 841 RLNRHKEL 848
++ +E+
Sbjct: 454 KIREQEEM 461
Score = 35.4 bits (80), Expect = 0.23
Identities = 16/62 (25%), Positives = 41/62 (66%), Gaps = 5/62 (8%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSR-----FEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ I+ + R +E+E+++++Q+E+ ++++++RE EE++ E EK
Sbjct: 299 EREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 358
Query: 291 AK 292
+
Sbjct: 359 IR 360
Score = 35.4 bits (80), Expect = 0.23
Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 9/58 (15%)
Query: 6 EKVEEEEEAEREEAAEWAE-----WARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
EK++E+EE RE+ + W + EKM R E+ E K+E +R+LE+K+ E
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE----KEEKIRELEEKMHE 355
Score = 34.3 bits (77), Expect = 0.52
Identities = 12/32 (37%), Positives = 27/32 (84%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+++++Q+E +++K++RE+EE++ E E+
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Score = 34.3 bits (77), Expect = 0.52
Identities = 12/32 (37%), Positives = 27/32 (84%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+++++Q+E +++K++RE+EE++ E E+
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Score = 33.5 bits (75), Expect = 0.88
Identities = 15/59 (25%), Positives = 41/59 (69%), Gaps = 1/59 (1%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+E I+++E+++ ++ K +EQE+E+++Q+E ++++++RE+E+++ E E+
Sbjct: 396 EEKIREQEEMMQEQEE-KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE 453
Score = 33.5 bits (75), Expect = 0.88
Identities = 14/55 (25%), Positives = 37/55 (67%), Gaps = 9/55 (16%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ I+ EQE+++++Q+E+ ++++++ E+EE++ E E+
Sbjct: 492 RQEEKIREQEKKIR---------EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Score = 32.7 bits (73), Expect = 1.5
Identities = 10/32 (31%), Positives = 27/32 (84%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+++++Q+E+ ++++++ E+EE++ E E+
Sbjct: 394 EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Score = 32.0 bits (71), Expect = 2.6
Identities = 20/61 (32%), Positives = 37/61 (60%), Gaps = 11/61 (18%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
K ++ ++EE + K+ I+ E E+++ +Q++IR QE+K R+EEE++ E E
Sbjct: 328 KEEKMRRQEEMMWEKEEKIR---------ELEEKMHEQEKIREQEEK--RQEEEKIREQE 376
Query: 290 K 290
K
Sbjct: 377 K 377
Score = 32.0 bits (71), Expect = 2.6
Identities = 17/59 (28%), Positives = 38/59 (64%), Gaps = 3/59 (5%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+E I+++E+ K+ + R+ R EQE ++ +Q+E ++++++RE+EE + E E+
Sbjct: 356 QEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Score = 31.6 bits (70), Expect = 3.4
Identities = 14/58 (24%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
K+ ++EEK+ ++ ++ + +EQE+++ +Q+E ++++++R +EE++ E E
Sbjct: 502 KKIREQEEKIREQEEMMQEQEE--KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Score = 31.6 bits (70), Expect = 3.4
Identities = 11/29 (37%), Positives = 24/29 (82%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLME 287
EQE+++++Q+E +++ RLR++EE++ E
Sbjct: 541 EQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 31.2 bits (69), Expect = 4.4
Identities = 17/66 (25%), Positives = 40/66 (60%), Gaps = 5/66 (7%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKK-----RLREEEERLM 286
+E I+++E+ + ++ + ++ R ++E +K+++IR E+K ++RE+EE+
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 287 EAEKAK 292
E EK +
Sbjct: 368 EEEKIR 373
Score = 31.2 bits (69), Expect = 4.4
Identities = 15/59 (25%), Positives = 42/59 (71%), Gaps = 3/59 (5%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+E ++++E+++ +K + R+L + +++++++Q+E R QE++++RE+E+R + K
Sbjct: 329 EEKMRRQEEMMWEKE--EKIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQEQEAK 384
Score = 31.2 bits (69), Expect = 4.4
Identities = 17/59 (28%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Query: 2 EVLREKVE--EEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
E +RE+ E +EEE RE+ + A+M + + ++E+I ++E +++ E+K+ E
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415
Score = 30.8 bits (68), Expect = 5.7
Identities = 13/54 (24%), Positives = 35/54 (64%), Gaps = 9/54 (16%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
++EEK+ ++ I+ EQE+++++Q+E+ ++++++ E+E ++ E E
Sbjct: 436 RQEEKIREQEKKIR---------EQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Score = 30.4 bits (67), Expect = 7.5
Identities = 12/55 (21%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++E+K+ ++ I+ ++ EQE+++ +Q+E +++++++E+EE++ E+
Sbjct: 499 EQEKKIREQEEKIREQEEMMQ--EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Score = 30.4 bits (67), Expect = 7.5
Identities = 11/32 (34%), Positives = 26/32 (81%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+++++Q+E ++++++RE+E RL + E+
Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEE 565
Score = 30.0 bits (66), Expect = 9.8
Identities = 14/59 (23%), Positives = 37/59 (62%), Gaps = 3/59 (5%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+E ++EEK+ ++ K + QE+++++Q+E ++++ ++E+EE++ E E+
Sbjct: 363 EEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 418
Score = 30.0 bits (66), Expect = 9.8
Identities = 18/56 (32%), Positives = 38/56 (67%), Gaps = 4/56 (7%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQE-IRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ ++ + R QE+++++Q++ IR QE+K +RE+EE + E E+
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRR--QEEKIREQEKKIREQEEK-IREQEEMMQEQEE 467
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 38.9 bits (89), Expect = 0.021
Identities = 45/241 (18%), Positives = 111/241 (46%), Gaps = 32/241 (13%)
Query: 613 EERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQY 672
EE+I + RE+ + E R+ E + +I + I + E + ++ +++
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK-IHEQEEKIRKQEEKMWRQ 562
Query: 673 EAMMHLKREEKLSRHQ--VWESELEVLE-ILKLREEEEAAHTLTISIYDTKRNEKSKEYR 729
E MH +EEK+ + VW E ++ E K+RE+EE I + E+ ++
Sbjct: 563 EEKMH-DQEEKIREQEEKVWRQEEKIREQEEKIREQEE-----KIREQEEMTQEQEEKMG 616
Query: 730 EAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKAN 789
E E+M +E Q + + + + +R +++ + + ++++ +
Sbjct: 617 EQEEKMCEQEEKMQEQEE--------------KMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 790 LIQARFEK---ETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQRLNRHK 846
++Q + EK + +++ ++++ QE + + ++E ++ + R+R E+++ H+
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW-----EQEVRLRQQEEKMQEHQ 717
Query: 847 E 847
E
Sbjct: 718 E 718
Score = 38.1 bits (87), Expect = 0.036
Identities = 44/203 (21%), Positives = 92/203 (45%), Gaps = 46/203 (22%)
Query: 663 EHTKKLLYQYEAMMHLKREEKLSRHQ--VWESELEVLEILKLREEEEAAHTLTISIYDTK 720
E +K+ Q E M ++EEK+ R + +WE E K+RE EE H
Sbjct: 407 EKEEKMRRQEEMMW--EKEEKMRRQEEMMWEKEE------KIRELEEKMH---------- 448
Query: 721 RNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDF 780
+ ++ RE E+ EE +R+ E + + A Q + +R ++E + +
Sbjct: 449 ---EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ---------EEKIREQEEKIREQ 496
Query: 781 KQRLINKANLI--QARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRIL 838
++++ + I Q + +E + ++++ W QE ++ E E+++ + +I
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIW-----RQKEKIHEQ 548
Query: 839 EQRLNRHKELAPLKYLALEEKLY 861
E+++ + +E K EEK++
Sbjct: 549 EEKIRKQEE----KMWRQEEKMH 567
Score = 35.4 bits (80), Expect = 0.23
Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 23/220 (10%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
K ++ ++EE + K+ I+ E E+++ +Q++IR QE+K R+EEE++ E E
Sbjct: 422 KEEKMRRQEEMMWEKEEKIR---------ELEEKMHEQEKIREQEEK--RQEEEKIREQE 470
Query: 290 KAKPDALHGLRVHSWVLVLSGK-REVPENFFIDPFTGHSYS--TQDEHFLGIESLWNHKN 346
K + R + K RE E + H ++E E +W +
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 347 YWINMQDCWNCCKDLIFDLGDPVRWEYMLLGTDKSQL-----SLTEEDDSGINDEDDV-- 399
++ W K+ I + + +R + + + ++ + E+++ E+ +
Sbjct: 531 KIREQEEIWR-QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIRE 589
Query: 400 -ENLGKEDEDKSFDMPHSWVEQIEISPEAFETRCPNGKKV 438
E +E E+K + EQ E E E C +K+
Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 629
Score = 34.3 bits (77), Expect = 0.52
Identities = 16/61 (26%), Positives = 43/61 (70%), Gaps = 1/61 (1%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEKA 291
+E ++++E+++ +K K R +E+E+++++Q+E+ ++++++RE EE++ E EK
Sbjct: 395 EEKMRRQEEMMWEKEE-KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 453
Query: 292 K 292
+
Sbjct: 454 R 454
Score = 34.3 bits (77), Expect = 0.52
Identities = 12/32 (37%), Positives = 27/32 (84%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+++++Q+E +++K++RE+EE++ E E+
Sbjct: 631 EQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Score = 33.5 bits (75), Expect = 0.88
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 12/63 (19%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEV---------RKEEITL-KQETLRDLEKK 55
EK+ E+EE R + E W + EKM R E+ R+EE+ K+E +R+LE+K
Sbjct: 389 EKIREQEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 446
Query: 56 LSE 58
+ E
Sbjct: 447 MHE 449
Score = 33.5 bits (75), Expect = 0.88
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
EK+ E+EE RE+ E W + EK+ ++R+EE +QE + E+K+ E
Sbjct: 484 EKIREQEEKIREQ--EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 534
Score = 33.5 bits (75), Expect = 0.88
Identities = 14/55 (25%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 5 REKV-EEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
+EK+ E+EE+ ++E W + +M + ++E++ ++E +R+ E+K+ E
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596
Score = 33.5 bits (75), Expect = 0.88
Identities = 14/55 (25%), Positives = 37/55 (67%), Gaps = 9/55 (16%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ I+ EQE+++++Q+E+ ++++++ E+EE++ E E+
Sbjct: 638 RQEEKIREQEKKIR---------EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Score = 33.1 bits (74), Expect = 1.2
Identities = 36/210 (17%), Positives = 100/210 (47%), Gaps = 20/210 (9%)
Query: 663 EHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRN 722
E K+ Q E + + + + ++W E ++ E K+REEE+ + + K
Sbjct: 474 EQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 533
Query: 723 EKSKEYREAMERMMHEEHLRQVETQL----DYLAPFLAQLPPGEKLTCW---QAVRLKDE 775
E+ + +R+ + EE +R+ E ++ + + ++ E+ W + +R ++E
Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE-KVWRQEEKIREQEE 592
Query: 776 CLSDFKQRLINKANLIQARFEK---ETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAM 832
+ + ++++ + + Q + EK + +++ ++++ QE + + ++E + +
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI-----REQE 647
Query: 833 FRIRILEQRLNRHKELAPLKYLALEEKLYK 862
+IR E+++ +E+ + EEK+++
Sbjct: 648 KKIREQEEKIREQEEMMQEQ----EEKMWE 673
Score = 32.3 bits (72), Expect = 2.0
Identities = 15/60 (25%), Positives = 37/60 (61%), Gaps = 5/60 (8%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFE-----QEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ I+ ++ E QE+++ +Q+E ++++++R +EE++ E EK
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK 648
Score = 32.0 bits (71), Expect = 2.6
Identities = 14/53 (26%), Positives = 35/53 (66%), Gaps = 2/53 (3%)
Query: 238 EEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EEK+ ++ I+ + EQE+++++Q+E+ ++++++R +EE + E E+
Sbjct: 374 EEKIQEQEEKIREQEEKIR--EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Score = 31.6 bits (70), Expect = 3.4
Identities = 44/225 (19%), Positives = 102/225 (45%), Gaps = 29/225 (12%)
Query: 601 EEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVE 660
EE + E+ + E+ ++R R++ + K E +RR E +M E E
Sbjct: 381 EEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQE------------EMMWEKE-E 424
Query: 661 PMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEE-AAHTLTISIYDT 719
M ++++++ E + E+ + ++ E E + E K+RE+E+ + +
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 720 KRNEKSKEYREAMERM------MHE-EHLRQVETQLDYLAPFLAQLPPGEKLTCW---QA 769
K E+ ++ RE E+M +HE E +R+ E + + + + E+ W +
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Query: 770 VRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQV 814
+ ++E + ++++ + + + EK + Q+++ W QE ++
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIRE--QEEKVWRQEEKI 587
Score = 31.6 bits (70), Expect = 3.4
Identities = 14/58 (24%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
K+ ++EEK+ ++ ++ + +EQE+++ +Q+E ++++++R +EE++ E E
Sbjct: 648 KKIREQEEKIREQEEMMQEQEE--KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Score = 31.2 bits (69), Expect = 4.4
Identities = 11/49 (22%), Positives = 29/49 (59%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEK 54
EK+ E+E+ + +EA W + ++ + + ++E++ ++E + + EK
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK 512
Score = 31.2 bits (69), Expect = 4.4
Identities = 22/71 (30%), Positives = 46/71 (64%), Gaps = 5/71 (7%)
Query: 222 REVCPLTVKPKETI-KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQE-IRAQEKKRLR 279
RE +T + +E + ++EEK+ ++ ++ + R QE+++++Q++ IR QE+K +R
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR--QEEKIREQEKKIREQEEK-IR 658
Query: 280 EEEERLMEAEK 290
E+EE + E E+
Sbjct: 659 EQEEMMQEQEE 669
Score = 31.2 bits (69), Expect = 4.4
Identities = 11/32 (34%), Positives = 26/32 (81%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+++++Q+E +++ RLR++EE++ E ++
Sbjct: 687 EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 30.4 bits (67), Expect = 7.5
Identities = 12/55 (21%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++E+K+ ++ I+ ++ EQE+++ +Q+E +++++++E+EE++ E+
Sbjct: 645 EQEKKIREQEEKIREQEEMMQ--EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Score = 30.0 bits (66), Expect = 9.8
Identities = 15/35 (42%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 259 EQEQEVKKQQE-IRAQEKKRLREEEERLMEAEKAK 292
EQE+++++Q+E IR QE+K R+EE + EK +
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 413
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 38.9 bits (89), Expect = 0.021
Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 5 REKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSEIQITVS 64
++K EEEE+ +REE E R E +R ++EE T KQ+ L L+K E ++T
Sbjct: 821 KKKQEEEEKKKREEEERERERERREAELR---AQQEEETRKQQELEALQKSQKEAELTRE 877
Query: 65 AELPAFTKDTIDISKL 80
E K +I +L
Sbjct: 878 LEKQKENKQVEEILRL 893
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/87 (26%), Positives = 43/87 (49%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
K +E +K+++ ++ + R+ R +QE+E +KQQE+ A +K + E R +E +
Sbjct: 822 KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQ 881
Query: 290 KAKPDALHGLRVHSWVLVLSGKREVPE 316
K LR+ + L +E E
Sbjct: 882 KENKQVEEILRLEKEIEDLQRMKEQQE 908
Score = 32.7 bits (73), Expect = 1.5
Identities = 17/36 (47%), Positives = 26/36 (72%), Gaps = 3/36 (8%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEKAKPD 294
++EQE KK+QE +E+K+ REEEER E E+ + +
Sbjct: 815 KREQEEKKKQE---EEEKKKREEEERERERERREAE 847
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 38.9 bits (89), Expect = 0.021
Identities = 21/65 (32%), Positives = 41/65 (63%), Gaps = 4/65 (6%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQE----IRAQEKKRLREEEERLME 287
KE +KE+K P K T+K ++ ++ ++E+E +K++E R +E + R+EEERL +
Sbjct: 325 KEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ 384
Query: 288 AEKAK 292
++ +
Sbjct: 385 EKRER 389
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 38.5 bits (88), Expect = 0.027
Identities = 48/192 (25%), Positives = 89/192 (46%), Gaps = 16/192 (8%)
Query: 679 KREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHE 738
++EE +S + E + E + L L+ EE HTL + + +K + R A+E ++
Sbjct: 171 RKEESISLMKETEGKREKINEL-LKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIYN 229
Query: 739 EHLRQVETQLDYLAPFLAQLPPGEK----LTCWQAVRLKDECLSDFKQRLINKANLIQAR 794
+ L + +LD L+ + GEK Q R K E + + L K + +
Sbjct: 230 QELNETRAKLDELS--AKRETSGEKSRQLRDAQQDARDKMEDIERQVREL--KTKISAMK 285
Query: 795 FEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRI-----RILEQRLNRHKELA 849
EKE ++++Q Q ++ L +D L+ S+ R+ ++LE+ + KELA
Sbjct: 286 EEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELA 345
Query: 850 PL--KYLALEEK 859
K+ +++EK
Sbjct: 346 ETEPKFNSVKEK 357
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 38.5 bits (88), Expect = 0.027
Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 43/191 (22%)
Query: 631 KREFLR-RTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQV 689
+REFLR + E S + + + +P H K LL+Q + + ++EE R +V
Sbjct: 352 RREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEE---RRRV 408
Query: 690 WESELEVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLD 749
E + E KL+E+E+ + E M+ + EE RQ E + +
Sbjct: 409 EEQQRREREQRKLQEKEQ------------------QRRLEDMQALRREEERRQAEREQE 450
Query: 750 YLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWY 809
Y + +L+++ S+ QR + + + + K Q+ Q++QQ
Sbjct: 451 Y-----------------KRKQLEEQRQSERLQRQLQQ----EHAYLKSLQQQQQQQQLQ 489
Query: 810 QENQVTLTPED 820
++ Q L P D
Sbjct: 490 KQQQQQLLPGD 500
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 38.5 bits (88), Expect = 0.027
Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 43/191 (22%)
Query: 631 KREFLR-RTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQV 689
+REFLR + E S + + + +P H K LL+Q + + ++EE R +V
Sbjct: 352 RREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEE---RRRV 408
Query: 690 WESELEVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLD 749
E + E KL+E+E+ + E M+ + EE RQ E + +
Sbjct: 409 EEQQRREREQRKLQEKEQ------------------QRRLEDMQALRREEERRQAEREQE 450
Query: 750 YLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWY 809
Y + +L+++ S+ QR + + + + K Q+ Q++QQ
Sbjct: 451 Y-----------------KRKQLEEQRQSERLQRQLQQ----EHAYLKSLQQQQQQQQLQ 489
Query: 810 QENQVTLTPED 820
++ Q L P D
Sbjct: 490 KQQQQQLLPGD 500
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 38.5 bits (88), Expect = 0.027
Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 43/191 (22%)
Query: 631 KREFLR-RTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQV 689
+REFLR + E S + + + +P H K LL+Q + + ++EE R +V
Sbjct: 352 RREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEE---RRRV 408
Query: 690 WESELEVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLD 749
E + E KL+E+E+ + E M+ + EE RQ E + +
Sbjct: 409 EEQQRREREQRKLQEKEQ------------------QRRLEDMQALRREEERRQAEREQE 450
Query: 750 YLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWY 809
Y + +L+++ S+ QR + + + + K Q+ Q++QQ
Sbjct: 451 Y-----------------KRKQLEEQRQSERLQRQLQQ----EHAYLKSLQQQQQQQQLQ 489
Query: 810 QENQVTLTPED 820
++ Q L P D
Sbjct: 490 KQQQQQLLPGD 500
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 38.5 bits (88), Expect = 0.027
Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 43/191 (22%)
Query: 631 KREFLR-RTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQV 689
+REFLR + E S + + + +P H K LL+Q + + ++EE R +V
Sbjct: 352 RREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEE---RRRV 408
Query: 690 WESELEVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLD 749
E + E KL+E+E+ + E M+ + EE RQ E + +
Sbjct: 409 EEQQRREREQRKLQEKEQ------------------QRRLEDMQALRREEERRQAEREQE 450
Query: 750 YLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWY 809
Y + +L+++ S+ QR + + + + K Q+ Q++QQ
Sbjct: 451 Y-----------------KRKQLEEQRQSERLQRQLQQ----EHAYLKSLQQQQQQQQLQ 489
Query: 810 QENQVTLTPED 820
++ Q L P D
Sbjct: 490 KQQQQQLLPGD 500
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 38.5 bits (88), Expect = 0.027
Identities = 84/417 (20%), Positives = 169/417 (40%), Gaps = 47/417 (11%)
Query: 436 KKVIQYKRAKLEKWAPYLNSNGLVSRLTTYEDLQCTNILEIKEWYQNREDMLELKHINKT 495
++ +Q +R +L++ + + S+ Y+ L+ T + E +E M E++H+ +
Sbjct: 1599 QEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNE------TQEKMCEIEHLKEQ 1652
Query: 496 TD--------LKTDYFKPGHPQALRVHSYKSMQPEMDRVIEFYETARVDGLMKREETPRT 547
+ ++T+ + + +S+ E D + ET +V+ +E T
Sbjct: 1653 FETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRET 1712
Query: 548 MTEYYQGRPDFLSYRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPAKPAEE--DVA 605
+T + + + L H + + R IV N K E D
Sbjct: 1713 ITRDLEKQEE-LKIVHMHLKEHQETI------DKLRGIVSEKTNEISNMQKDLEHSNDAL 1765
Query: 606 ERVFLVAEERIQLRY-HCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVEPMEH 664
+ L +E +++ + H +E T K + + D N M D+ S + E
Sbjct: 1766 KAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSN---MQKDLENS-NAKLQEK 1821
Query: 665 TKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRNEK 724
++L ++ LK++ ++ +V E +E LK + ++++ + I + +K
Sbjct: 1822 IQELKANEHQLITLKKDVNETQKKVSE-----MEQLKKQIKDQSLTLSKLEIENLNLAQK 1876
Query: 725 SKEYREAMERMMHE-EHLRQVETQL----DYLAPFLAQLPPG------EKLTCWQAVRLK 773
E E M+ +M E ++LR+VE L D L L + E T +
Sbjct: 1877 LHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEH 1936
Query: 774 DECLSDFKQRLINKA---NLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSY 827
E + ++++ K + IQ +K ELQKK Q Q+ ++ L ED+ +S+
Sbjct: 1937 KETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSH 1993
Score = 34.3 bits (77), Expect = 0.52
Identities = 24/96 (25%), Positives = 51/96 (53%), Gaps = 6/96 (6%)
Query: 2 EVLREKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSEIQI 61
E L+EK ++ +E +++ E + M+K + +E K E+ K+ TL +E + E+
Sbjct: 1127 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQ 1186
Query: 62 TVS---AELPAFTKDTIDISKLPISYKTNTPKEEHL 94
++ E+ + TK+ + +L S++T + +HL
Sbjct: 1187 KLNENYEEVKSITKERKVLKELQKSFET---ERDHL 1219
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 38.5 bits (88), Expect = 0.027
Identities = 35/113 (30%), Positives = 48/113 (42%), Gaps = 15/113 (13%)
Query: 342 WNHKNYWINMQDCW-NCCKDLIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDDVE 400
WN K I +D W K L +++ WE G S ++DD G ED
Sbjct: 574 WNKKTALIRARDPWAQDTKLLDYEVDSDEEWEEEEPGESLSHSEGDDDDDMG---ED--- 627
Query: 401 NLGKEDEDKSFDMPHSWVEQIEISPEAFETRCPNGKKVIQYKRAKLEKWAPYL 453
EDED F +PH ++ + E E E P KV Q +AK +W +L
Sbjct: 628 ----EDEDDGFFVPHGYLSEDEGVTE--ECADPENHKVRQKLKAK--EWDEFL 672
Score = 36.6 bits (83), Expect = 0.10
Identities = 24/63 (38%), Positives = 42/63 (66%), Gaps = 7/63 (11%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQ--EVKKQQEIRAQEKKRLREEEERLMEAE 289
+E +K+EK +K +K R R E+++ E K +++ + +E+KRLREEE+R+ +AE
Sbjct: 387 REKREKDEKEKAEKQRLKEER----RKERQEALEAKLEEKRKKEEEKRLREEEKRI-KAE 441
Query: 290 KAK 292
KA+
Sbjct: 442 KAE 444
Score = 30.8 bits (68), Expect = 5.7
Identities = 19/74 (25%), Positives = 40/74 (54%), Gaps = 5/74 (6%)
Query: 228 TVKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQE-----QEVKKQQEIRAQEKKRLREEE 282
T K K ++++++ L K+ ++ R+ + ++E +E KK++E + K++ R E+
Sbjct: 330 TEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK 389
Query: 283 ERLMEAEKAKPDAL 296
E EKA+ L
Sbjct: 390 REKDEKEKAEKQRL 403
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 37.4 bits (85), Expect = 0.061
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 23/194 (11%)
Query: 654 CISFE-VEPMEHTKKLLYQYE---AMMHLKREEKLSRHQVWESELEVLEILKLREEEEAA 709
C+ E V E K LL YE ++ + EE S + +S+L LE+ E+
Sbjct: 817 CLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDL--LEMKNANEKTRLE 874
Query: 710 H-TLTISIYDTKR--------NEKSKEY---REAMERMMHEEHLRQVETQLDYLAPFLAQ 757
+ L I + + + NEK K + E ++ ++ ++ LR +L L LA+
Sbjct: 875 NQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAK 934
Query: 758 LPP--GEKLTCWQAVRLKDECLSDF---KQRLINKANLIQARFEKETQELQKKQQWYQEN 812
P + L+ + + K E L K+ INK L+ + +KE +K+ Q +E
Sbjct: 935 SPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEE 994
Query: 813 QVTLTPEDEDLYLS 826
+L E + L S
Sbjct: 995 LESLRSEKDQLSAS 1008
Score = 37.0 bits (84), Expect = 0.080
Identities = 86/444 (19%), Positives = 172/444 (38%), Gaps = 49/444 (11%)
Query: 458 LVSRLTTYEDLQCTNILEIKEWYQNRE----DMLELKHINKTTDLKTDYFKPGHPQALRV 513
L S L YE + E++E +E D+LE+K+ N+ T L+ + +
Sbjct: 829 LKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQT 888
Query: 514 HSYKSMQPEMDRVIEFYETARVDGLMKREETPRTMTEYYQGRPDFLSYRHASFGPRVKKL 573
S + E ++ E + L++++E E L + P VK
Sbjct: 889 CSKSEIHNEKEKCF-IKEHENLKPLLEQKELRDRRAEL------ILLKDSLAKSPSVKND 941
Query: 574 TLSSAESNPRPIVKITE------------RFFRNPAKPAEEDVAERVFLVAEERIQLRYH 621
LSS + I + + + AK + + V EE LR
Sbjct: 942 PLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLR-- 999
Query: 622 CREDHITASKREFLRRTE--------VDSKGNKIIMTPDMCISFEVEPMEHTKKL---LY 670
+D ++AS R+ ++ E + + ++ + + +FE + T++L
Sbjct: 1000 SEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTL 1059
Query: 671 QYEAMMHLKREEKLSRHQVWESELEVLEILKLR-EEEEAAHTLTISIYDTKRNEKSKEYR 729
Q E + + E+ L+R + +S ++LE+ L + +A + ++ +K KE+
Sbjct: 1060 QCETI-NSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHA 1118
Query: 730 EAMERMMH-EEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKD--ECLSDFKQRLIN 786
+ + + L++ + QL L + + T + + D + + Q+L N
Sbjct: 1119 TTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTN 1178
Query: 787 KANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQRLNRHK 846
K N I+ +L+++ + ++ Q TL E L S +I + + K
Sbjct: 1179 KNNKIE--------DLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKK 1230
Query: 847 ELAPLKYLALEEKLYKDPRLGELQ 870
ELA K + + + GEL+
Sbjct: 1231 ELADSKQAETDHLILQASLKGELE 1254
Score = 30.8 bits (68), Expect = 5.7
Identities = 38/222 (17%), Positives = 90/222 (40%), Gaps = 11/222 (4%)
Query: 627 ITASKREFLRRTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSR 686
I + + L R E K++ ++ ++ K ++ + L++E+K+
Sbjct: 1064 INSDNEDLLARIETLQSNAKLL-------EVQILEVQRAKAMVDKELEAEKLQKEQKIKE 1116
Query: 687 HQVWESELEVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVET 746
H +ELE L++ +E+++ T+ + + + + ME +E ++++
Sbjct: 1117 HATTVNELEELQVQLQKEKKQLQKTM--QELELVKKDAQQTTLMNMEIADYERLMKELNQ 1174
Query: 747 QLDYLAPFLAQLPPGEKLTCWQAVRLKDE--CLSDFKQRLINKANLIQARFEKETQELQK 804
+L + L K+ + L++E L Q+ K I+ K +EL
Sbjct: 1175 KLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELAD 1234
Query: 805 KQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQRLNRHK 846
+Q ++ + +L S +++I++ E +HK
Sbjct: 1235 SKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHK 1276
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 37.4 bits (85), Expect = 0.061
Identities = 47/240 (19%), Positives = 105/240 (43%), Gaps = 13/240 (5%)
Query: 583 RPIVKITERFFRNPAKPAEEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDS 642
+ I K E+ +R + E++ R R + R +E + ++E + E+
Sbjct: 286 KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345
Query: 643 KGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMH----LKREEKLSRHQ---VWESELE 695
+ ++ + E + E +K+ Q E + ++ +E+ R Q +WE +
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER 405
Query: 696 VLEIL-KLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPF 754
+ E ++RE+E+ + + K E+ K+ R+ E+M EE +R+ E ++
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465
Query: 755 LAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQV 814
+ + EK+ + + E +QRL + + +E+E + Q+++ W QE ++
Sbjct: 466 MRE--QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL---WEQEKMQEQEEKIWEQEEKI 520
Score = 36.2 bits (82), Expect = 0.14
Identities = 22/72 (30%), Positives = 43/72 (59%), Gaps = 9/72 (12%)
Query: 219 DLTREVCPLTVKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRL 278
++ R+ L + K+ K+EEK+ ++ ++ EQE ++++Q+E +++KRL
Sbjct: 273 EMWRQEEELREQEKKIRKQEEKMWRQEERLR---------EQEGKMREQEEKMWRQEKRL 323
Query: 279 REEEERLMEAEK 290
RE+E+ L E EK
Sbjct: 324 REQEKELREQEK 335
Score = 36.2 bits (82), Expect = 0.14
Identities = 16/32 (50%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQEQ+++ Q+E ++ +RLRE+EER+ E EK
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Score = 35.8 bits (81), Expect = 0.18
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 35/158 (22%)
Query: 658 EVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIY 717
E E M ++ + + E M + E++ + ++ E + ++ E K++E+EE I+
Sbjct: 462 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE-------KIW 514
Query: 718 DTKRNEKSKEYREAME-RMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDEC 776
+ + + +E E +M +E +R+ E Q+ W+ ++E
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM------------------WE----QEEK 552
Query: 777 LSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQV 814
+ D +Q++ ++ + R EK+TQE Q+K+ W QE ++
Sbjct: 553 MRDQEQKMWDQ----EERMEKKTQE-QEKKTWDQEEKM 585
Score = 35.4 bits (80), Expect = 0.23
Identities = 35/165 (21%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 660 EPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISI--Y 717
E M ++ ++ E M K +E+ + W+ E ++ E ++RE E+ +
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQ--EKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 718 DTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAP----------FLAQLPPGEKLTCW 767
+ K E+ ++ +E E+M +E Q + + + + Q P +K W
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 768 QAVRLKD-ECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQE 811
+ ++++ E + + ++++ Q + EK+TQE Q+K+ W QE
Sbjct: 669 EHEKMQEQEKMQEQEEKIWE-----QEKMEKKTQE-QEKKTWDQE 707
Score = 33.9 bits (76), Expect = 0.68
Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 5/63 (7%)
Query: 6 EKVEEEEEAEREEAAEW--AEWARMEKMMRPVEVR---KEEITLKQETLRDLEKKLSEIQ 60
E++ E+EE RE+ W E R EK M+ E + +EE ++E +R+ EKK+ E +
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEE 463
Query: 61 ITV 63
T+
Sbjct: 464 ETM 466
Score = 33.9 bits (76), Expect = 0.68
Identities = 20/68 (29%), Positives = 40/68 (58%), Gaps = 14/68 (20%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKK-----RLREEEERLM 286
KE + ++EK+ ++ I +EQE++++ Q+E+ QEKK ++RE+E+++
Sbjct: 497 KEKLWEQEKMQEQEEKI---------WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547
Query: 287 EAEKAKPD 294
E E+ D
Sbjct: 548 EQEEKMRD 555
Score = 33.5 bits (75), Expect = 0.88
Identities = 14/32 (43%), Positives = 28/32 (87%), Gaps = 1/32 (3%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+E+++Q+E+R QE ++++E+EE++ E E+
Sbjct: 332 EQEKELREQKELREQE-EQMQEQEEKMWEQEE 362
Score = 32.7 bits (73), Expect = 1.5
Identities = 13/58 (22%), Positives = 39/58 (67%), Gaps = 3/58 (5%)
Query: 233 ETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
E +++E+K+ ++ K RD + ++E+ ++++++ +E++ +RE+EE++ + E+
Sbjct: 424 EKMREEKKMQEQE---KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478
Score = 32.7 bits (73), Expect = 1.5
Identities = 13/55 (23%), Positives = 38/55 (69%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
KK ++ K + + R+ S E+E+++++++E+ +++++++E+EE++ E E+
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Score = 32.3 bits (72), Expect = 2.0
Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 3/53 (5%)
Query: 9 EEEEEAEREEAAEWAEWARMEKMMRPVEVR---KEEITLKQETLRDLEKKLSE 58
E+EE+ +E W + RMEK + E + +EE ++E +R+ EKK+ E
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Score = 32.3 bits (72), Expect = 2.0
Identities = 16/75 (21%), Positives = 46/75 (61%), Gaps = 5/75 (6%)
Query: 221 TREVCPLTVKPKETIKKEEKVLPKKYTIKPPRDLCSRFE-----QEQEVKKQQEIRAQEK 275
T+E T +E +++EE++ ++ ++ ++ E QE+++++Q+E +++
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 276 KRLREEEERLMEAEK 290
++++E+EE++ E E+
Sbjct: 631 EKMQEQEEKMWEQEE 645
Score = 32.3 bits (72), Expect = 2.0
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 3/55 (5%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEVR--KEEITLKQETLRDLEKKLSE 58
EK++E+E+ + +E W E +MEK + E + +E ++E++R+ EKK+ E
Sbjct: 671 EKMQEQEKMQEQEEKIW-EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE 724
Score = 32.0 bits (71), Expect = 2.6
Identities = 15/61 (24%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
+ ++ ++++EK L ++ K R+ EQE+++++Q+E ++++++RE+EE++ E
Sbjct: 318 RQEKRLREQEKELREQE--KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Query: 290 K 290
+
Sbjct: 376 E 376
Score = 32.0 bits (71), Expect = 2.6
Identities = 18/74 (24%), Positives = 44/74 (59%), Gaps = 5/74 (6%)
Query: 222 REVCPLTVKPKETIKKEEKVLPKKYTIKPPRDLCSR-----FEQEQEVKKQQEIRAQEKK 276
RE L + ++ ++EEK+ ++ ++ + R +EQE+++++Q++ +++
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 277 RLREEEERLMEAEK 290
R+ E++ERL E E+
Sbjct: 398 RMWEQDERLREKEE 411
Score = 32.0 bits (71), Expect = 2.6
Identities = 20/58 (34%), Positives = 37/58 (63%), Gaps = 6/58 (10%)
Query: 5 REKVEEEEEA--EREEAAEWAE--WARMEKMMRPVEVRKEEITL--KQETLRDLEKKL 56
+EK++E+EE E+EE E W + +KM R ++R++E + ++E +RD E+K+
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Score = 31.6 bits (70), Expect = 3.4
Identities = 18/62 (29%), Positives = 40/62 (64%), Gaps = 3/62 (4%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQ--EQEVKKQQEIRAQEK-KRLREEEERLMEA 288
+E ++++EK+ + ++ + + + ++ +QE K Q+E R +E+ K++REEEE + E
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQ 469
Query: 289 EK 290
E+
Sbjct: 470 EE 471
Score = 31.6 bits (70), Expect = 3.4
Identities = 17/56 (30%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKK-QQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ + + + QEQE K QE + +E++R+RE E+++ E E+
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
Score = 31.6 bits (70), Expect = 3.4
Identities = 13/59 (22%), Positives = 39/59 (66%), Gaps = 2/59 (3%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+E +++EE + ++ ++ ++ EQE+++++Q+E ++++ + E+EE++ E E+
Sbjct: 706 QEKMREEESMREREKKMREEEEMMR--EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Score = 31.2 bits (69), Expect = 4.4
Identities = 18/65 (27%), Positives = 40/65 (61%), Gaps = 8/65 (12%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQ------QEIRAQEKKRLREEEERL 285
+E +++EE++ ++ ++ + EQE++++KQ QE + +++RL E++E+L
Sbjct: 443 EEKMQEEERIREREKKMREEEETMR--EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Query: 286 MEAEK 290
E EK
Sbjct: 501 WEQEK 505
Score = 31.2 bits (69), Expect = 4.4
Identities = 15/55 (27%), Positives = 36/55 (65%), Gaps = 1/55 (1%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ K ++ + ++++++++ +R +EKK +REEEE + E E+
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKK-MREEEEMMREQEE 734
Score = 30.8 bits (68), Expect = 5.7
Identities = 15/68 (22%), Positives = 42/68 (61%), Gaps = 5/68 (7%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSR-----FEQEQEVKKQQEIRAQEKKRLREEEERLM 286
++ ++++EK L ++ ++ + +EQE+++++Q+E ++++RL E+E+++
Sbjct: 327 EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386
Query: 287 EAEKAKPD 294
E E+ D
Sbjct: 387 EQEQKMRD 394
Score = 30.8 bits (68), Expect = 5.7
Identities = 12/59 (20%), Positives = 41/59 (69%), Gaps = 3/59 (5%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
K+T ++E+K ++ ++ + E+E+++++++E+ +++++++E+EE++ E E+
Sbjct: 569 KKTQEQEKKTWDQEEKMREEERMR---EREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 37.4 bits (85), Expect = 0.061
Identities = 48/242 (19%), Positives = 103/242 (42%), Gaps = 28/242 (11%)
Query: 598 KPAEEDVAERVFLVAEERIQLRYHCREDHITASKREFL---------------RRTEVDS 642
K ++ E++ L E+ +++ + +E + +FL + E+
Sbjct: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 643 KGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKL 702
+ KI + E E K+ Q E M ++ + ++ E E E+ E KL
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKL 305
Query: 703 REEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGE 762
RE+EE +++ + EK +E E M R EE L + E Q+ Q +
Sbjct: 306 REQEEQMQEQEEKMWE--QEEKMREQEEKMWR--QEERLWEQEKQMRE----QEQKMRDQ 357
Query: 763 KLTCWQAVRLKDECLSDFKQRLINKANL-IQARFEKETQELQKKQQWYQENQVTLTPEDE 821
+ W+ +DE L + ++R+ + + Q +E + ++++++ +E + T+ ++E
Sbjct: 358 EERMWE----QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE 413
Query: 822 DL 823
+
Sbjct: 414 KM 415
Score = 37.0 bits (84), Expect = 0.080
Identities = 22/72 (30%), Positives = 43/72 (59%), Gaps = 9/72 (12%)
Query: 219 DLTREVCPLTVKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRL 278
++ R+ L + K+ K+EEK+ ++ ++ EQE ++++Q+E +++KRL
Sbjct: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLR---------EQEGKMREQEEKMRRQEKRL 285
Query: 279 REEEERLMEAEK 290
RE+E+ L E EK
Sbjct: 286 REQEKELREQEK 297
Score = 36.2 bits (82), Expect = 0.14
Identities = 16/32 (50%), Positives = 25/32 (78%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQEQ+++ Q+E ++ +RLRE+EER+ E EK
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEK 380
Score = 36.2 bits (82), Expect = 0.14
Identities = 38/163 (23%), Positives = 76/163 (46%), Gaps = 16/163 (9%)
Query: 658 EVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIY 717
E E M ++ + + E M + E++ + ++ E + ++ E K++E+EE I
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
Query: 718 DTKR--NEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDE 775
D + ++ K +R+ R ++ Q E D Q ++ W+ +DE
Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ-----EQKMWDQEERMWE----QDE 514
Query: 776 CLSDFKQRLINKANLIQ----ARFEKETQELQKKQQWYQENQV 814
L + ++R+ + + Q R EK+TQE Q+K+ W QE ++
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQE-QEKKTWDQEEKM 556
Score = 35.4 bits (80), Expect = 0.23
Identities = 35/159 (22%), Positives = 70/159 (44%), Gaps = 42/159 (26%)
Query: 660 EPMEHTKKLLYQYEAMMHLKREEKLSRHQ---VWESELEVLEILKLREEEEAAHTLTISI 716
E M KK+ Q E M REEK ++ Q W+ E ++ E ++RE E+
Sbjct: 521 ERMREQKKMWQQEEKM----REEKKTQEQEKKTWDQEEKMREEERMREREK--------- 567
Query: 717 YDTKRNEKSKEYREAMERMM-HEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDE 775
K E+ + RE E+M EE +R+ E ++ W+ ++E
Sbjct: 568 ---KMREEEEMMREQEEKMQEQEEKMREQEEKM------------------WE----QEE 602
Query: 776 CLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQV 814
+ + ++++ + + + E++ + Q++ W QE ++
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM 641
Score = 33.9 bits (76), Expect = 0.68
Identities = 15/53 (28%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
E++ E+EE RE+ W + +M++ R + R++++ ++ET+R+ E+K+ +
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEER-IREREKKMREEEETMREQEEKMQK 417
Score = 33.9 bits (76), Expect = 0.68
Identities = 20/68 (29%), Positives = 40/68 (58%), Gaps = 14/68 (20%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKK-----RLREEEERLM 286
KE + ++EK+ ++ I +EQE++++ Q+E+ QEKK ++RE+E+++
Sbjct: 439 KEKLWEQEKMQEQEEKI---------WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 287 EAEKAKPD 294
E E+ D
Sbjct: 490 EQEEKMRD 497
Score = 33.9 bits (76), Expect = 0.68
Identities = 15/55 (27%), Positives = 37/55 (67%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ K +EQE+++++Q+E ++++++RE+EE++ E E+
Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
Score = 33.5 bits (75), Expect = 0.88
Identities = 15/33 (45%), Positives = 27/33 (81%), Gaps = 1/33 (3%)
Query: 258 FEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+EQE+++++++ IR +EKK +REEEE + E E+
Sbjct: 382 WEQEEKMQEEERIREREKK-MREEEETMREQEE 413
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/32 (43%), Positives = 27/32 (84%), Gaps = 1/32 (3%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
EQE+E+++Q++ +E+K+LRE+EE++ E E+
Sbjct: 287 EQEKELREQEK-ELREQKKLREQEEQMQEQEE 317
Score = 32.7 bits (73), Expect = 1.5
Identities = 16/75 (21%), Positives = 46/75 (61%), Gaps = 5/75 (6%)
Query: 221 TREVCPLTVKPKETIKKEEKVLPKKYTIKPPRDLCSRFE-----QEQEVKKQQEIRAQEK 275
T+E T +E +++EE++ ++ ++ ++ E QE+++++Q+E +++
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Query: 276 KRLREEEERLMEAEK 290
++++E+EE++ E E+
Sbjct: 602 EKMQEQEEKMWEQEE 616
Score = 32.3 bits (72), Expect = 2.0
Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRK-----EEITLKQETLRDLEKKLSE 58
E++ E+EE RE+ W + +M + + E K EE ++E +R+ EKK+ E
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Score = 32.3 bits (72), Expect = 2.0
Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 10/63 (15%)
Query: 1 MEVLREKVEEEEEAER-EEAAEWAE----WARMEKMMRPVEVRKEEITLKQETLRDLEKK 55
M+ EK+ E+EE R +E W + W + EKM E+R+ K+E +RD ++K
Sbjct: 683 MQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE-----KEERIRDQKEK 737
Query: 56 LSE 58
+ E
Sbjct: 738 MQE 740
Score = 32.0 bits (71), Expect = 2.6
Identities = 15/61 (24%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query: 230 KPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAE 289
+ ++ ++++EK L ++ K R+ EQE+++++Q+E ++++++RE+EE++ E
Sbjct: 280 RQEKRLREQEKELREQE--KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
Query: 290 K 290
+
Sbjct: 338 E 338
Score = 32.0 bits (71), Expect = 2.6
Identities = 18/74 (24%), Positives = 44/74 (59%), Gaps = 5/74 (6%)
Query: 222 REVCPLTVKPKETIKKEEKVLPKKYTIKPPRDLCSR-----FEQEQEVKKQQEIRAQEKK 276
RE L + ++ ++EEK+ ++ ++ + R +EQE+++++Q++ +++
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 277 RLREEEERLMEAEK 290
R+ E++ERL E E+
Sbjct: 360 RMWEQDERLREKEE 373
Score = 32.0 bits (71), Expect = 2.6
Identities = 20/58 (34%), Positives = 37/58 (63%), Gaps = 6/58 (10%)
Query: 5 REKVEEEEEA--EREEAAEWAE--WARMEKMMRPVEVRKEEITL--KQETLRDLEKKL 56
+EK++E+EE E+EE E W + +KM R ++R++E + ++E +RD E+K+
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Score = 31.6 bits (70), Expect = 3.4
Identities = 14/32 (43%), Positives = 24/32 (75%)
Query: 259 EQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+QEQ++ Q+E ++ +RLRE+EER+ E +K
Sbjct: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKK 528
Score = 31.6 bits (70), Expect = 3.4
Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 14/94 (14%)
Query: 658 EVEPMEHTKKLLYQYEAMMHLKREEKLSRHQ--VWESELEVLEILKLREEEEAAHTLTIS 715
E + E +K+ Q E M + E+K+ + +WE E K++E+EE
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE------KMQEQEEKMWE---- 650
Query: 716 IYDTKRNEKSKEYREAMERMM-HEEHLRQVETQL 748
+ K E+ ++ RE E+M EE +R+ E ++
Sbjct: 651 -QEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Score = 31.2 bits (69), Expect = 4.4
Identities = 18/65 (27%), Positives = 40/65 (61%), Gaps = 8/65 (12%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQ------QEIRAQEKKRLREEEERL 285
+E +++EE++ ++ ++ + EQE++++KQ QE + +++RL E++E+L
Sbjct: 385 EEKMQEEERIREREKKMREEEETMR--EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 286 MEAEK 290
E EK
Sbjct: 443 WEQEK 447
Score = 31.2 bits (69), Expect = 4.4
Identities = 15/62 (24%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Query: 229 VKPKETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEA 288
++ +E + +EK + ++ ++ D +EQE++++ Q++ +++R+ E++ERL E
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQED--QMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 289 EK 290
E+
Sbjct: 520 EE 521
Score = 31.2 bits (69), Expect = 4.4
Identities = 12/55 (21%), Positives = 37/55 (67%)
Query: 236 KKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
++EEK+ ++ + + E+E ++++Q+E+ +++++++E+EE++ E E+
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Score = 31.2 bits (69), Expect = 4.4
Identities = 16/53 (30%), Positives = 33/53 (62%), Gaps = 4/53 (7%)
Query: 6 EKVEEEEEAEREEAAEWAEWARMEKMMRPVEVRKEEITLKQETLRDLEKKLSE 58
EK+ E+EE ++ + E W + EKM + ++E++ ++E +R+ E+K+ E
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKM----QEQEEKMWEQEEKMREQEEKMRE 664
Score = 30.8 bits (68), Expect = 5.7
Identities = 15/68 (22%), Positives = 42/68 (61%), Gaps = 5/68 (7%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSR-----FEQEQEVKKQQEIRAQEKKRLREEEERLM 286
++ ++++EK L ++ ++ + +EQE+++++Q+E ++++RL E+E+++
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 348
Query: 287 EAEKAKPD 294
E E+ D
Sbjct: 349 EQEQKMRD 356
Score = 30.8 bits (68), Expect = 5.7
Identities = 13/31 (41%), Positives = 23/31 (74%)
Query: 260 QEQEVKKQQEIRAQEKKRLREEEERLMEAEK 290
+EQE +QE + QE++R+RE E+++ E E+
Sbjct: 376 REQEKMWEQEEKMQEEERIREREKKMREEEE 406
Score = 30.4 bits (67), Expect = 7.5
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 6/60 (10%)
Query: 232 KETIKKEEKVLPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEK-KRLREEEERLMEAEK 290
K+ ++EEK+ +K T + + +QE K ++E R +E+ K++REEEE + E E+
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTW-----DQEEKMREEERMREREKKMREEEEMMREQEE 581
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 37.4 bits (85), Expect = 0.061
Identities = 46/212 (21%), Positives = 90/212 (42%), Gaps = 19/212 (8%)
Query: 655 ISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTI 714
+SF E ++ ++ + + E+ ++ E S V + + E++ + R+E E H +
Sbjct: 537 LSFSREQIQRARQTIAEQESKLN---EAHKSLSTVEDLKAEIVSASESRKELELKHEAEV 593
Query: 715 SIYDTKRNEKSKEYREAMERM--MHEEHLRQVETQL-----DYLAPFLAQLPPGEKLTCW 767
+ Y K KE ++RM E L ++ TQL + L+ L ++
Sbjct: 594 TNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRI--- 650
Query: 768 QAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSY 827
+LKD +KQ++ N + + ET + +K ++NQ+ L E L
Sbjct: 651 NIEKLKDNLGIHYKQQIDGLQNEMSQKI--ETMQFEKDNLITKQNQLIL----EISKLKD 704
Query: 828 CSQAMFRIRILEQRLNRHKELAPLKYLALEEK 859
Q++ + E L ++ ++ L EEK
Sbjct: 705 LQQSLVNSKSEEMTLQINELQKEIEILRQEEK 736
Score = 30.8 bits (68), Expect = 5.7
Identities = 47/214 (21%), Positives = 99/214 (46%), Gaps = 18/214 (8%)
Query: 666 KKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRNEKS 725
+ LL + +A+ K++ + ESE E+L+ +++ + L + + + +++
Sbjct: 3088 RSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRA 3147
Query: 726 KEYREAM--ERMMHEEHLRQV-ETQLDYLAPFLAQLPPGEKLTCWQAVRLKDE-----CL 777
E +E + E+M+ E ++ +T+L+ AQ ++L ++ + +KD+ L
Sbjct: 3148 TELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFR-LEVKDKTDEVHLL 3206
Query: 778 SDFKQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRI 837
+D K+ +Q EKE +L + ++ +E E EDL S SQ ++
Sbjct: 3207 NDTLASEQKKSRELQWALEKEKAKLGRSEERDKE-------ELEDLKFSLESQKQRNLQ- 3258
Query: 838 LEQRLNRHKELAPLKYLALE-EKLYKDPRLGELQ 870
L L + K+L +E +++ D +L E Q
Sbjct: 3259 LNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQ 3292
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 37.4 bits (85), Expect = 0.061
Identities = 46/212 (21%), Positives = 90/212 (42%), Gaps = 19/212 (8%)
Query: 655 ISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTI 714
+SF E ++ ++ + + E+ ++ E S V + + E++ + R+E E H +
Sbjct: 537 LSFSREQIQRARQTIAEQESKLN---EAHKSLSTVEDLKAEIVSASESRKELELKHEAEV 593
Query: 715 SIYDTKRNEKSKEYREAMERM--MHEEHLRQVETQL-----DYLAPFLAQLPPGEKLTCW 767
+ Y K KE ++RM E L ++ TQL + L+ L ++
Sbjct: 594 TNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRI--- 650
Query: 768 QAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSY 827
+LKD +KQ++ N + + ET + +K ++NQ+ L E L
Sbjct: 651 NIEKLKDNLGIHYKQQIDGLQNEMSQKI--ETMQFEKDNLITKQNQLIL----EISKLKD 704
Query: 828 CSQAMFRIRILEQRLNRHKELAPLKYLALEEK 859
Q++ + E L ++ ++ L EEK
Sbjct: 705 LQQSLVNSKSEEMTLQINELQKEIEILRQEEK 736
Score = 30.8 bits (68), Expect = 5.7
Identities = 47/214 (21%), Positives = 99/214 (46%), Gaps = 18/214 (8%)
Query: 666 KKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRNEKS 725
+ LL + +A+ K++ + ESE E+L+ +++ + L + + + +++
Sbjct: 3080 RSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRA 3139
Query: 726 KEYREAM--ERMMHEEHLRQV-ETQLDYLAPFLAQLPPGEKLTCWQAVRLKDE-----CL 777
E +E + E+M+ E ++ +T+L+ AQ ++L ++ + +KD+ L
Sbjct: 3140 TELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFR-LEVKDKTDEVHLL 3198
Query: 778 SDFKQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRI 837
+D K+ +Q EKE +L + ++ +E E EDL S SQ ++
Sbjct: 3199 NDTLASEQKKSRELQWALEKEKAKLGRSEERDKE-------ELEDLKFSLESQKQRNLQ- 3250
Query: 838 LEQRLNRHKELAPLKYLALE-EKLYKDPRLGELQ 870
L L + K+L +E +++ D +L E Q
Sbjct: 3251 LNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQ 3284
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 37.4 bits (85), Expect = 0.061
Identities = 57/219 (26%), Positives = 99/219 (45%), Gaps = 29/219 (13%)
Query: 673 EAMMHLKRE--EKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTK-RNEKSKEYR 729
EA L+R+ E L++ + E + LE L + EA S++D + E +
Sbjct: 282 EANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREAT-----SLHDANDKLENELASK 336
Query: 730 EAMERMMHEEHLRQVETQLDYLAPFLAQ-------LPPGEKLTCWQAVRLK--DECLSDF 780
E++ R EE RQ+ LD L Q LP E + L +E +F
Sbjct: 337 ESLYRQS-EEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNF 395
Query: 781 KQRLINKANLIQARFEKETQELQKKQQWYQENQV--TLTPEDEDLYLSYCSQAMF----- 833
++RL ++A+ E++ QELQ+ +Q + N E D LS ++ +
Sbjct: 396 EERL----RQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKE 451
Query: 834 RIRILEQRLNRHKELAPLKYLALEEKLYKDPRLGELQKI 872
R+ LE++ + +E+A +K L E L K+ L E++++
Sbjct: 452 RMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERM 490
>gi|28195388 RAB11 family interacting protein 4 (class II) [Homo
sapiens]
Length = 637
Score = 37.0 bits (84), Expect = 0.080
Identities = 49/217 (22%), Positives = 82/217 (37%), Gaps = 45/217 (20%)
Query: 589 TERFFRNPAKPAEEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKII 648
TE FR+ + D+ E+V + ++ +L D +T + + E +++
Sbjct: 325 TEDLFRDSIDSCDNDITEKVSFLEKKVTELE----NDSLTNGDLKSKLKQENTQLVHRVH 380
Query: 649 MTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEA 708
+M V+ E T + + EA H + KL R + E EL + +L EE
Sbjct: 381 ELEEM-----VKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEENTE 435
Query: 709 AHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQ 768
T + + EK E R+ M + + L
Sbjct: 436 LRTTVTRL--KSQTEKLDEERQRMSDRLEDTSL--------------------------- 466
Query: 769 AVRLKDECLSDFKQRLINKANLIQARFEKE---TQEL 802
RLKDE D +R+++K + F+KE TQEL
Sbjct: 467 --RLKDE--MDLYKRMMDKLRQNRLEFQKEREATQEL 499
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,040,191
Number of Sequences: 37866
Number of extensions: 1765954
Number of successful extensions: 14749
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 10751
Number of HSP's gapped (non-prelim): 3556
length of query: 874
length of database: 18,247,518
effective HSP length: 111
effective length of query: 763
effective length of database: 14,044,392
effective search space: 10715871096
effective search space used: 10715871096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.