Search of human proteins with 223941803

Search of human proteins with 223941803

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223941803 N-glycanase 1 isoform 3 [Homo sapiens]
         (612 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223941803 N-glycanase 1 isoform 3 [Homo sapiens]                  1255   0.0  
gi|21314690 N-glycanase 1 isoform 1 [Homo sapiens]                   1254   0.0  
gi|223941798 N-glycanase 1 isoform 2 [Homo sapiens]                  1130   0.0  
gi|223941808 N-glycanase 1 isoform 4 [Homo sapiens]                  1023   0.0  
gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein...    38   0.031
gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]               36   0.12 
gi|46276885 WD repeat domain 78 isoform 2 [Homo sapiens]               36   0.12 
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa...    35   0.15 
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa...    35   0.15 
gi|4502613 cyclin A [Homo sapiens]                                     35   0.26 
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 34   0.34 
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 34   0.34 
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  34   0.34 
gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]            34   0.45 
gi|50345997 E1A binding protein p300 [Homo sapiens]                    33   0.59 
gi|224809302 xeroderma pigmentosum, complementation group C isof...    33   0.59 
gi|224809295 xeroderma pigmentosum, complementation group C isof...    33   0.59 
gi|11067749 bromodomain containing protein 3 [Homo sapiens]            33   1.0  
gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]      32   1.7  
gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ...    32   1.7  
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          31   2.9  
gi|221139926 NHS-like 1 [Homo sapiens]                                 31   3.8  
gi|13376854 UBX domain protein 6 [Homo sapiens]                        31   3.8  
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     30   5.0  
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]    30   6.5  
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]    30   6.5  
gi|124517695 ankyrin repeat domain 36B [Homo sapiens]                  30   6.5  
gi|16753207 ubiquilin 2 [Homo sapiens]                                 30   8.5  
gi|56549111 optineurin [Homo sapiens]                                  30   8.5  
gi|56549109 optineurin [Homo sapiens]                                  30   8.5  

>gi|223941803 N-glycanase 1 isoform 3 [Homo sapiens]
          Length = 612

 Score = 1255 bits (3248), Expect = 0.0
 Identities = 612/612 (100%), Positives = 612/612 (100%)

Query: 1   MRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 60
           MRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR
Sbjct: 1   MRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 60

Query: 61  DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 120
           DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA
Sbjct: 61  DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 120

Query: 121 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180
           STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN
Sbjct: 121 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180

Query: 181 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 240
           ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY
Sbjct: 181 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 240

Query: 241 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 300
           CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY
Sbjct: 241 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 300

Query: 301 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR 360
           SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR
Sbjct: 301 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR 360

Query: 361 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS 420
           TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS
Sbjct: 361 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS 420

Query: 421 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW 480
           VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW
Sbjct: 421 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW 480

Query: 481 KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE 540
           KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE
Sbjct: 481 KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE 540

Query: 541 WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE 600
           WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE
Sbjct: 541 WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE 600

Query: 601 NCLEIIIKFSDL 612
           NCLEIIIKFSDL
Sbjct: 601 NCLEIIIKFSDL 612


>gi|21314690 N-glycanase 1 isoform 1 [Homo sapiens]
          Length = 654

 Score = 1254 bits (3245), Expect = 0.0
 Identities = 611/612 (99%), Positives = 612/612 (100%)

Query: 1   MRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 60
           +RNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR
Sbjct: 43  LRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 102

Query: 61  DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 120
           DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA
Sbjct: 103 DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 162

Query: 121 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180
           STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN
Sbjct: 163 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222

Query: 181 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 240
           ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY
Sbjct: 223 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 282

Query: 241 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 300
           CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY
Sbjct: 283 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 342

Query: 301 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR 360
           SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR
Sbjct: 343 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR 402

Query: 361 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS 420
           TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS
Sbjct: 403 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS 462

Query: 421 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW 480
           VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW
Sbjct: 463 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW 522

Query: 481 KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE 540
           KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE
Sbjct: 523 KMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVE 582

Query: 541 WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE 600
           WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE
Sbjct: 583 WKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEE 642

Query: 601 NCLEIIIKFSDL 612
           NCLEIIIKFSDL
Sbjct: 643 NCLEIIIKFSDL 654


>gi|223941798 N-glycanase 1 isoform 2 [Homo sapiens]
          Length = 636

 Score = 1130 bits (2922), Expect = 0.0
 Identities = 571/613 (93%), Positives = 575/613 (93%), Gaps = 20/613 (3%)

Query: 1   MRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 60
           +RNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR
Sbjct: 43  LRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 102

Query: 61  DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 120
           DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA
Sbjct: 103 DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 162

Query: 121 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180
           STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN
Sbjct: 163 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222

Query: 181 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 240
           ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY
Sbjct: 223 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 282

Query: 241 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 300
           CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYT+       
Sbjct: 283 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTE------- 335

Query: 301 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSK-DEVVDVTWRYSCKHEEVIAR 359
               QR L             L EI  GK    +    K  +VVDVTWRYSCKHEEVIAR
Sbjct: 336 ---LQRTLSLKL-------TTLKEI--GKTFLRISKRQKLIQVVDVTWRYSCKHEEVIAR 383

Query: 360 RTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISG 419
           RTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISG
Sbjct: 384 RTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISG 443

Query: 420 SVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGV 479
           SVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGV
Sbjct: 444 SVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGV 503

Query: 480 WKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTV 539
           WKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTV
Sbjct: 504 WKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTV 563

Query: 540 EWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHE 599
           EWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHE
Sbjct: 564 EWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHE 623

Query: 600 ENCLEIIIKFSDL 612
           ENCLEIIIKFSDL
Sbjct: 624 ENCLEIIIKFSDL 636


>gi|223941808 N-glycanase 1 isoform 4 [Homo sapiens]
          Length = 558

 Score = 1023 bits (2644), Expect = 0.0
 Identities = 494/496 (99%), Positives = 496/496 (100%)

Query: 1   MRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 60
           +RNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR
Sbjct: 43  LRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 102

Query: 61  DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 120
           DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA
Sbjct: 103 DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 162

Query: 121 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180
           STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN
Sbjct: 163 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222

Query: 181 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 240
           ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY
Sbjct: 223 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 282

Query: 241 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 300
           CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY
Sbjct: 283 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 342

Query: 301 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR 360
           SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR
Sbjct: 343 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARR 402

Query: 361 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS 420
           TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS
Sbjct: 403 TKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGS 462

Query: 421 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW 480
           VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW
Sbjct: 463 VAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVW 522

Query: 481 KMESIFRKVETDWHMV 496
           KMESIFRKVETDWHM+
Sbjct: 523 KMESIFRKVETDWHMI 538


>gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein
           [Homo sapiens]
          Length = 614

 Score = 37.7 bits (86), Expect = 0.031
 Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 377 KQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKE 436
           +Q+Q+ +     K++LQ++  E++  +SP+  KP E     +G+V   V      L R+ 
Sbjct: 266 RQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRES 325

Query: 437 TLFIPCE--NEKISKQLHLCYNIVKDRYVRVSN 467
              + CE   E+++  +   + I+K    ++ N
Sbjct: 326 MWDLSCETVREQLTNSIRKQWRILKSHVEKLDN 358


>gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]
          Length = 848

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 17/116 (14%)

Query: 71  LDGSNKSHKVKSSQQPAASTQLPTTPSS-----NPSGLNQHTRNRQGQSSDPPSASTVAA 125
           L G+ K  K+ +SQ+ +  ++  ++ S      NPS L Q TR+  G S+   S S+V+A
Sbjct: 135 LTGTAKPSKLLTSQEGSLGSEFISSYSLYQNTINPSTLGQFTRSVLGSST--VSKSSVSA 192

Query: 126 DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINI 181
             +I E L          E P+ + + L      ++ R + EK+     L+K I I
Sbjct: 193 SESIAEDL----------EEPSYKRERLTSFTDLQVIRAAPEKIVTKEDLEKNIEI 238


>gi|46276885 WD repeat domain 78 isoform 2 [Homo sapiens]
          Length = 545

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 17/116 (14%)

Query: 71  LDGSNKSHKVKSSQQPAASTQLPTTPSS-----NPSGLNQHTRNRQGQSSDPPSASTVAA 125
           L G+ K  K+ +SQ+ +  ++  ++ S      NPS L Q TR+  G S+   S S+V+A
Sbjct: 135 LTGTAKPSKLLTSQEGSLGSEFISSYSLYQNTINPSTLGQFTRSVLGSST--VSKSSVSA 192

Query: 126 DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINI 181
             +I E L          E P+ + + L      ++ R + EK+     L+K I I
Sbjct: 193 SESIAEDL----------EEPSYKRERLTSFTDLQVIRAAPEKIVTKEDLEKNIEI 238


>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
            sapiens]
          Length = 1690

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 290  DYTDHVWT---EVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVT 346
            D T H+W      + PS+ R+LH    + + +KPL  +   GK  S      K E V+  
Sbjct: 1460 DETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVK---GKDSSEKKRKRKLEKVEQL 1516

Query: 347  WRYSCKHEEVIARRTKVKEALLR---DTINGLNKQRQLFLSENRRKELLQRIIVELVEFI 403
            +    +  + + +  K ++  L+   D    LNK  +    E  RK+  ++     VE +
Sbjct: 1517 FGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEERKKKKEKAAAAKVELV 1576

Query: 404  SPKTPKPGE 412
               T K  E
Sbjct: 1577 KESTEKKRE 1585


>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
            sapiens]
          Length = 1641

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 290  DYTDHVWT---EVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVT 346
            D T H+W      + PS+ R+LH    + + +KPL  +   GK  S      K E V+  
Sbjct: 1465 DETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVK---GKDSSEKKRKRKLEKVEQL 1521

Query: 347  WRYSCKHEEVIARRTKVKEALLR---DTINGLNKQRQLFLSENRRKELLQRIIVELVEFI 403
            +    +  + + +  K ++  L+   D    LNK  +    E  RK+  ++     VE +
Sbjct: 1522 FGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEERKKKKEKAAAAKVELV 1581

Query: 404  SPKTPKPGE 412
               T K  E
Sbjct: 1582 KESTEKKRE 1590


>gi|4502613 cyclin A [Homo sapiens]
          Length = 432

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 15/118 (12%)

Query: 62  LIAIERSSRLDGSNKSHKVKSS--QQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPS 119
           L+A+++++  +     +  K++  QQP     L    S NP GL Q  R         P 
Sbjct: 18  LLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQR---------PK 68

Query: 120 ASTVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDK 177
              VA     L+ L  N +HV V    A  ++    I V E ++++Q+K + ++K+++
Sbjct: 69  TRRVAP----LKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIER 122


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%)

Query: 34   FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 93
            + + + E + H+  P   S   L+   D+ + ++ S     + S +   ++  ++S++  
Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218

Query: 94   TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 135
            +TPSSN    NQ H  + Q +S  P  A+T    S   E +Q+
Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%)

Query: 34   FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 93
            + + + E + H+  P   S   L+   D+ + ++ S     + S +   ++  ++S++  
Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218

Query: 94   TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 135
            +TPSSN    NQ H  + Q +S  P  A+T    S   E +Q+
Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%)

Query: 34   FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 93
            + + + E + H+  P   S   L+   D+ + ++ S     + S +   ++  ++S++  
Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218

Query: 94   TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 135
            +TPSSN    NQ H  + Q +S  P  A+T    S   E +Q+
Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261


>gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]
          Length = 298

 Score = 33.9 bits (76), Expect = 0.45
 Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 15/138 (10%)

Query: 75  NKSHKVKSSQQPAASTQLPTTP--------SSNPSGLNQHTRNRQGQSSDPPSASTVAA- 125
           N   + K+     AST LP +P        S+ PS  +QH R  Q  S +PP+     A 
Sbjct: 4   NTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPSPAP 63

Query: 126 -----DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180
                +S+  E     +  V++  +P + + +LA +   + +R   E+L      ++ + 
Sbjct: 64  DDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGE-DVYERTLT 122

Query: 181 ISDEDFLLLELLHWFKEE 198
           +  ED  L+ +  W  E+
Sbjct: 123 VDGEDTTLVVVDTWEAEK 140


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 33.5 bits (75), Expect = 0.59
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 10/114 (8%)

Query: 81   KSSQQPAASTQLPTTPSSNP---SGLNQHTRNRQGQSSDPPSASTVAADSAIL------- 130
            +S Q  AAS   PT P   P   + L+Q   + +GQ S+PPS S+   +S  +       
Sbjct: 915  RSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQ 974

Query: 131  EVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDE 184
            EV       V   E    Q + ++   V++ K +S E   R+ +L   I   ++
Sbjct: 975  EVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEED 1028


>gi|224809302 xeroderma pigmentosum, complementation group C isoform
           2 [Homo sapiens]
          Length = 903

 Score = 33.5 bits (75), Expect = 0.59
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 296 WTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDE-VVDVTWRY 349
           W EV+   +++W+  D    V  +PL       K ++YV+    D  V DVT RY
Sbjct: 494 WLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRY 548


>gi|224809295 xeroderma pigmentosum, complementation group C isoform
           1 [Homo sapiens]
          Length = 940

 Score = 33.5 bits (75), Expect = 0.59
 Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 296 WTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDE-VVDVTWRY 349
           W EV+   +++W+  D    V  +PL       K ++YV+    D  V DVT RY
Sbjct: 531 WLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRY 585


>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
          Length = 726

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 2/70 (2%)

Query: 54  EQLQKIRDLIAIERSSRLDG--SNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQ 111
           +Q  K ++ +A E+   L+    + S ++ SS++PA   +  + PS  PS L+  + +  
Sbjct: 651 KQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSES 710

Query: 112 GQSSDPPSAS 121
           G SS   S+S
Sbjct: 711 GSSSSSGSSS 720



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 81  KSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQHV 140
           K   +P  +  LP   +   S   + +R+ +  SSD  S+ +    +  L  LQ  ++  
Sbjct: 414 KMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLK-- 471

Query: 141 LVYENPALQEKALACIPVQELKRKSQEKLSRARKLDK 177
            V+E  A    AL+  PV + K+K ++K    +K DK
Sbjct: 472 AVHEQLA----ALSQAPVNKPKKKKEKKEKEKKKKDK 504


>gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]
          Length = 144

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 26/112 (23%)

Query: 11  SIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQL-QKIRDLIAIERSS 69
           S+R+ N++    ++    A++   E   +  ++HL++  +  VE L ++I++LI  E++S
Sbjct: 36  SVRLDNSSSGASVV----AIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELI--EKNS 89

Query: 70  RLDGSNKSHKVKSSQ-------------------QPAASTQLPTTPSSNPSG 102
           +L+  N   K  +S                    QP  +TQ P  P+S  SG
Sbjct: 90  QLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSG 141


>gi|183396804 Regulation of nuclear pre-mRNA domain containing 2
           [Homo sapiens]
          Length = 1461

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)

Query: 36  MGFEEGETHLIFPKK-ASVEQLQKIRDLIAIERSSRLDGSNK----SHKVKSSQQPAAST 90
           MG EE ++  +  +K A+ E +   RD+  +E S   D  +K      K K +++ A ST
Sbjct: 341 MGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVST 400

Query: 91  QLPTTPSSNPSGLNQHTRNRQGQSSDPP 118
            +PT P+ N S  +  T      ++ PP
Sbjct: 401 SVPTKPTENISKASSCTPVPVTMTATPP 428


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 45   LIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLN 104
            L+FP   + E L     L    R  + D S K    K+S     STQ PT  S  PSG N
Sbjct: 1320 LLFPSSLAGETLGSFSGL----RVGQADDSTKPTN-KASSTSLTSTQ-PTKTSGVPSGFN 1373

Query: 105  QHTRNRQGQSSDPPSASTVAADS 127
                   G+ ++PP  S+    S
Sbjct: 1374 FTAPPVLGKHTEPPVTSSATTTS 1396


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%)

Query: 49   KKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAAST-QLPTTPSSNPSGLNQHT 107
            ++ + EQ   +     ++ S+ L   N +++++S  QPA+ T  LPT   S+  G +   
Sbjct: 1094 ERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSA 1153

Query: 108  RNRQGQSSDPPSASTVAADSA 128
              R G  S  P A +     A
Sbjct: 1154 AERGGPVSRSPGAPSAGEAEA 1174


>gi|13376854 UBX domain protein 6 [Homo sapiens]
          Length = 441

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 13/38 (34%), Positives = 22/38 (57%)

Query: 3   NPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEE 40
           +P +EKYR I++ N  F  R+  + G  E    +GF++
Sbjct: 188 HPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQK 225


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 7/125 (5%)

Query: 65  IERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVA 124
           +ER  RL    K  K K+ +Q         +PSS  S  +Q     Q     P S + ++
Sbjct: 802 VERERRLIRKEKVEKDKTDKQKRKGKV--HSPSSQSSETDQENEREQSPEK-PRSCNKLS 858

Query: 125 ADSAILEVLQSN----IQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180
            + A  E +  N    +  V++      + K +   PV++LK K      ++  LD+ + 
Sbjct: 859 REKADKEGIAKNRLELMPCVVLTRVKEKEGKVIDHTPVEKLKAKLDNDTVKSSALDQKLQ 918

Query: 181 ISDED 185
           +S  +
Sbjct: 919 VSQTE 923


>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
          Length = 710

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 4/74 (5%)

Query: 39  EEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSS 98
           E  ++  + P+K S +++   + +  +  ++R+ G  KS  V S +QPA+ T    T S+
Sbjct: 119 EGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSA 178

Query: 99  NPSGLNQHTRNRQG 112
               LN  T  + G
Sbjct: 179 ----LNTATEIKDG 188


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 22/94 (23%)

Query: 29   AVECLFEMGFEEGETHLIFPKKASVEQL-QKIRDLIAIERSSRLDGSNKSHKVKSSQ--- 84
            A++   E   +  ++HL++  +  VE L ++I++LI  E++S+L+  N   K  +S    
Sbjct: 979  AIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELI--EKNSQLEQENNLLKTLASPEQL 1036

Query: 85   ----------------QPAASTQLPTTPSSNPSG 102
                            QP  +TQ P  P+S  SG
Sbjct: 1037 AQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSG 1070


>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
          Length = 1121

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 4/74 (5%)

Query: 39  EEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSS 98
           E  ++  + P+K S +++   + +  +  ++R+ G  KS  V S +QPA+ T    T S+
Sbjct: 84  EGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSA 143

Query: 99  NPSGLNQHTRNRQG 112
               LN  T  + G
Sbjct: 144 ----LNTATEIKDG 153


>gi|16753207 ubiquilin 2 [Homo sapiens]
          Length = 624

 Score = 29.6 bits (65), Expect = 8.5
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 68  SSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADS 127
           SS  +G+  S        P      P T SS  +     T +  G SS   + +TVAA +
Sbjct: 299 SSSGEGTQPSRTENRDPLPNPWAPPPATQSSATTSTTTSTGSGSGNSSSNATGNTVAAAN 358

Query: 128 AILEV-----LQSNIQHVLVYENPALQEKALA 154
            +  +     +QS +Q +   ENP L +  L+
Sbjct: 359 YVASIFSTPGMQSLLQQIT--ENPQLIQNMLS 388


>gi|56549111 optineurin [Homo sapiens]
          Length = 577

 Score = 29.6 bits (65), Expect = 8.5
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 97  SSNPSGLNQHTR----NRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKA 152
           S+ PS LN+       N++ +       S +  + A  E  +S +  + +  N  LQE  
Sbjct: 342 SAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHN 401

Query: 153 LACIPVQELKRKSQEKLSRA--RKLDKGINISDE 184
            A   ++EL RK  EK+ RA  ++L + + ++++
Sbjct: 402 NALKTIEELTRKESEKVDRAVLKELSEKLELAEK 435


>gi|56549109 optineurin [Homo sapiens]
          Length = 577

 Score = 29.6 bits (65), Expect = 8.5
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 97  SSNPSGLNQHTR----NRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKA 152
           S+ PS LN+       N++ +       S +  + A  E  +S +  + +  N  LQE  
Sbjct: 342 SAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHN 401

Query: 153 LACIPVQELKRKSQEKLSRA--RKLDKGINISDE 184
            A   ++EL RK  EK+ RA  ++L + + ++++
Sbjct: 402 NALKTIEELTRKESEKVDRAVLKELSEKLELAEK 435


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,575,000
Number of Sequences: 37866
Number of extensions: 1073891
Number of successful extensions: 3709
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 3685
Number of HSP's gapped (non-prelim): 47
length of query: 612
length of database: 18,247,518
effective HSP length: 108
effective length of query: 504
effective length of database: 14,157,990
effective search space: 7135626960
effective search space used: 7135626960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.