Guide to the Human Genome
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Search of human proteins with 223555924

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223555924 transmembrane protein 71 isoform 1 [Homo sapiens]
         (276 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223555924 transmembrane protein 71 isoform 1 [Homo sapiens]        563   e-161
gi|223555926 transmembrane protein 71 isoform 2 [Homo sapiens]        350   6e-97
gi|66346695 fibrillin 2 precursor [Homo sapiens]                       34   0.16 
gi|22094125 zinc finger protein 28 [Homo sapiens]                      33   0.35 
gi|223633988 hypothetical protein LOC85379 [Homo sapiens]              30   3.0  
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [...    30   3.0  
gi|223671927 hypothetical protein LOC222234 isoform 2 [Homo sapi...    30   3.0  
gi|223671925 hypothetical protein LOC222234 isoform 1 [Homo sapi...    30   3.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    29   3.9  
gi|4506303 protein tyrosine phosphatase, receptor type, A isofor...    29   3.9  
gi|39995071 exonuclease 1 isoform b [Homo sapiens]                     29   5.1  
gi|39995069 exonuclease 1 isoform a [Homo sapiens]                     29   5.1  
gi|18491016 exonuclease 1 isoform b [Homo sapiens]                     29   5.1  
gi|124244056 family with sequence similarity 123B [Homo sapiens]       28   6.7  
gi|24430141 fibrillin 1 precursor [Homo sapiens]                       28   6.7  
gi|56237021 fibrillin 3 precursor [Homo sapiens]                       28   6.7  
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i...    28   8.7  
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i...    28   8.7  
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i...    28   8.7  
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is...    28   8.7  

>gi|223555924 transmembrane protein 71 isoform 1 [Homo sapiens]
          Length = 276

 Score =  563 bits (1452), Expect = e-161
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MYRISQLMSTPVASSSRLEREYAGELSPTCIFPSFTCDSLDGYHSFECGSIDPLTGSHYT 60
           MYRISQLMSTPVASSSRLEREYAGELSPTCIFPSFTCDSLDGYHSFECGSIDPLTGSHYT
Sbjct: 1   MYRISQLMSTPVASSSRLEREYAGELSPTCIFPSFTCDSLDGYHSFECGSIDPLTGSHYT 60

Query: 61  CRRSPRLLTNGYYIWTEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDIN 120
           CRRSPRLLTNGYYIWTEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDIN
Sbjct: 61  CRRSPRLLTNGYYIWTEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDIN 120

Query: 121 SSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKMNAESVITSSSSHIISQPPG 180
           SSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKMNAESVITSSSSHIISQPPG
Sbjct: 121 SSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKMNAESVITSSSSHIISQPPG 180

Query: 181 GNSHSLSLQSQLTASERFQENSSDHSETRLLQEVFFQAILLAVCLIISACARWFMGEILA 240
           GNSHSLSLQSQLTASERFQENSSDHSETRLLQEVFFQAILLAVCLIISACARWFMGEILA
Sbjct: 181 GNSHSLSLQSQLTASERFQENSSDHSETRLLQEVFFQAILLAVCLIISACARWFMGEILA 240

Query: 241 SVFTCSLMITVAYVKSLFLSLASYFKTTACARFVKI 276
           SVFTCSLMITVAYVKSLFLSLASYFKTTACARFVKI
Sbjct: 241 SVFTCSLMITVAYVKSLFLSLASYFKTTACARFVKI 276


>gi|223555926 transmembrane protein 71 isoform 2 [Homo sapiens]
          Length = 232

 Score =  350 bits (899), Expect = 6e-97
 Identities = 193/295 (65%), Positives = 200/295 (67%), Gaps = 82/295 (27%)

Query: 1   MYRISQLMSTPVASSSRLEREYAGELSPTCIFPSFTCDSLDGYHSFECGSIDPLTGSHYT 60
           MYRISQLMSTPVASSSRLEREYAGELSPTCIFPSFTCDSLDGYHSFECGSIDPLTGSHYT
Sbjct: 1   MYRISQLMSTPVASSSRLEREYAGELSPTCIFPSFTCDSLDGYHSFECGSIDPLTGSHYT 60

Query: 61  CRRSPRLLTNGYYIWTEDSFLCDKDGNITLNPSQTSVMYKENLV---------------- 104
           CRRSPRLLTNGYYIWTEDSFLCDKDGNITLNPSQTSVMYKENLV                
Sbjct: 61  CRRSPRLLTNGYYIWTEDSFLCDKDGNITLNPSQTSVMYKENLVRIFRKKKRICHSFSSL 120

Query: 105 ---STSKSWLHGSIFGDINSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKM 161
              STSKSWLHGSIFG                            D++ S   D+W  G  
Sbjct: 121 FNLSTSKSWLHGSIFG----------------------------DINSSPSEDNWLKG-- 150

Query: 162 NAESVITSSSSHIISQPPGGNSHSLSLQSQLTASERFQENSSDHSETRLLQEVFFQAILL 221
                                            + R   +  + +ETRLLQEVFFQAILL
Sbjct: 151 ---------------------------------TRRLDTDHCNGNETRLLQEVFFQAILL 177

Query: 222 AVCLIISACARWFMGEILASVFTCSLMITVAYVKSLFLSLASYFKTTACARFVKI 276
           AVCLIISACARWFMGEILASVFTCSLMITVAYVKSLFLSLASYFKTTACARFVKI
Sbjct: 178 AVCLIISACARWFMGEILASVFTCSLMITVAYVKSLFLSLASYFKTTACARFVKI 232


>gi|66346695 fibrillin 2 precursor [Homo sapiens]
          Length = 2912

 Score = 33.9 bits (76), Expect = 0.16
 Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 12/66 (18%)

Query: 34   SFTCDSLDGYHSF-----ECGSIDPLTGSHYTCRRSPRLLTNGYYIWTEDSFLCDKDGNI 88
            SF C+  +GY S       C  ID        C R+P L   G  + TE SF CD     
Sbjct: 1137 SFECECFEGYESGFMMMKNCMDIDE-------CERNPLLCRGGTCVNTEGSFQCDCPLGH 1189

Query: 89   TLNPSQ 94
             L+PS+
Sbjct: 1190 ELSPSR 1195


>gi|22094125 zinc finger protein 28 [Homo sapiens]
          Length = 868

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 34/144 (23%), Positives = 61/144 (42%), Gaps = 15/144 (10%)

Query: 74  IWTEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDINSS-------PSED 126
           IW  +S L    G+    P   S++ +E      K  L GS+F    S        P +D
Sbjct: 257 IWENNSDL-GSAGHCVAKPDLVSLLEQEKEPWMVKRELTGSLFSGQRSVHETQELFPKQD 315

Query: 127 NWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKMNAESVITSSSSHIISQPPGGNSHSL 186
           ++ +G     TD  +     LDCSS  ++W+S  +    +     +    Q P  ++ +L
Sbjct: 316 SYAEGV----TDRTSNTK--LDCSSFRENWDSDYVFGRKLAVGQETQ-FRQEPITHNKTL 368

Query: 187 SLQSQLTASERFQENSSDHSETRL 210
           S + + T ++  +    D SE ++
Sbjct: 369 SKERERTYNKSGRWFYLDDSEEKV 392


>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
          Length = 1806

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 11/115 (9%)

Query: 107  SKSWLHGSIFGDINSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKMNAESV 166
            S  W   S   D  S P  D   +   R  T+  + +    +  S    W     + ES+
Sbjct: 1492 SVPWRSHSFCKDRRSGPFVDQLKQCFSRQPTEPKDTDTLVHEAGSQYGTWTEQCQSGESL 1551

Query: 167  IT----SSSSHIISQPPGGNSHSLSLQSQLTAS------ERFQENSS-DHSETRL 210
             T    SS++    QPP     SLS Q++ T++       R Q ++S DHS T L
Sbjct: 1552 ATESPDSSATSTRKQPPSSRLSSLSSQTEPTSAGDQYDCSRDQRSTSVDHSSTDL 1606


>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a
           [Homo sapiens]
          Length = 1336

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)

Query: 158 SGKMNAESVITS--SSSHIISQPPGGNSHSLSLQSQLTASERFQENSSDHSETRLLQE 213
           SG+  A S+ TS  SSSH+  +PP G+S S   +S LT    FQ+      E +L ++
Sbjct: 813 SGRKRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLT---YFQQQLKPGKEDKLFRK 867


>gi|223671927 hypothetical protein LOC222234 isoform 2 [Homo
           sapiens]
          Length = 275

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 50  SIDPLTGSHYTCRRSPRLLTNGYYIWTEDSFLCDKDGNITL 90
           +ID L GS  T      LL    Y++TE SFL    G+ITL
Sbjct: 104 TIDKLQGSSVTVSTEDGLL-KAKYLYTESSFLSSAAGDITL 143


>gi|223671925 hypothetical protein LOC222234 isoform 1 [Homo
           sapiens]
          Length = 392

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 50  SIDPLTGSHYTCRRSPRLLTNGYYIWTEDSFLCDKDGNITL 90
           +ID L GS  T      LL    Y++TE SFL    G+ITL
Sbjct: 221 TIDKLQGSSVTVSTEDGLL-KAKYLYTESSFLSSAAGDITL 260


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 32/138 (23%), Positives = 58/138 (42%), Gaps = 9/138 (6%)

Query: 76  TEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDINSSPSEDNWLKGTRRL 135
           ++ S   D D + + N S +S    ++  S+  S    S     +SS SE +      + 
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSS----DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640

Query: 136 DTDHCNG-----NADDLDCSSLTDDWESGKMNAESVITSSSSHIISQPPGGNSHSLSLQS 190
           D+   N      N+D  D S+ ++  +S   +  S  +SSS    S     +S S +   
Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSE 700

Query: 191 QLTASERFQENSSDHSET 208
              +S+    +SSD S++
Sbjct: 701 SSDSSDSSDSDSSDSSDS 718



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 7/94 (7%)

Query: 120 NSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKMN-----AESVITSSSSHI 174
           +S  S+ +    + R D+ + + ++D  D S+ +D  +S   N     ++S  +S+SS  
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903

Query: 175 ISQPPGGNSHSLSLQSQLTASERFQENSSDHSET 208
            S     +S S    +   +SE    NSSD+S +
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSE--SSNSSDNSNS 935


>gi|4506303 protein tyrosine phosphatase, receptor type, A isoform 1
           precursor [Homo sapiens]
          Length = 802

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 64  SPRLLTNGYYIWTEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDINSSP 123
           SP +     Y+ T +S   D D   T   S  S+      +S + +WL  + F D  + P
Sbjct: 66  SPNITLGPTYLTTVNS--SDSDNGTTRTASTNSIGIT---ISPNGTWLPDNQFTDARTEP 120

Query: 124 SEDNWLKGTRRLDTDHCNGNADDLD 148
            E N        +T   +GN+D  D
Sbjct: 121 WEGNSSTAATTPETFPPSGNSDSKD 145


>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 10/80 (12%)

Query: 76  TEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDINSSPSEDNWLKGTRRL 135
           T   F C  D    ++   +     E  V+  ++ LH S +GD           +G R +
Sbjct: 502 TRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGD----------QEGKRLV 551

Query: 136 DTDHCNGNADDLDCSSLTDD 155
           DTD    ++DD+  + +  D
Sbjct: 552 DTDVARNSSDDIPNNHIPGD 571


>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
          Length = 803

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 10/80 (12%)

Query: 76  TEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDINSSPSEDNWLKGTRRL 135
           T   F C  D    ++   +     E  V+  ++ LH S +GD           +G R +
Sbjct: 502 TRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGD----------QEGKRLV 551

Query: 136 DTDHCNGNADDLDCSSLTDD 155
           DTD    ++DD+  + +  D
Sbjct: 552 DTDVARNSSDDIPNNHIPGD 571


>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
          Length = 846

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 10/80 (12%)

Query: 76  TEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDINSSPSEDNWLKGTRRL 135
           T   F C  D    ++   +     E  V+  ++ LH S +GD           +G R +
Sbjct: 502 TRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGD----------QEGKRLV 551

Query: 136 DTDHCNGNADDLDCSSLTDD 155
           DTD    ++DD+  + +  D
Sbjct: 552 DTDVARNSSDDIPNNHIPGD 571


>gi|124244056 family with sequence similarity 123B [Homo sapiens]
          Length = 1135

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 9/72 (12%)

Query: 115 IFGDINSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKMNAESVITSSSSHI 174
           +FGD+ S  S D+ L G        C     + D  S+TD   SG   A    T  SS +
Sbjct: 312 LFGDVTSLKSFDS-LTG--------CGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCL 362

Query: 175 ISQPPGGNSHSL 186
           ++   GG   +L
Sbjct: 363 VTYQGGGEEMAL 374


>gi|24430141 fibrillin 1 precursor [Homo sapiens]
          Length = 2871

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 11/53 (20%)

Query: 34  SFTCDSLDGYHSF----ECGSIDPLTGSHYTCRRSPRLLTNGYYIWTEDSFLC 82
           S+TC    GY S     EC  ID        C ++ R+  NG  I T+ SF C
Sbjct: 510 SYTCQCRAGYQSTLTRTECRDIDE-------CLQNGRICNNGRCINTDGSFHC 555


>gi|56237021 fibrillin 3 precursor [Homo sapiens]
          Length = 2809

 Score = 28.5 bits (62), Expect = 6.7
 Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 7/73 (9%)

Query: 30   CIFPSFTCDSLDGYHSFECG-SIDPLTGS------HYTCRRSPRLLTNGYYIWTEDSFLC 82
            C      C +L G  +  C   + PL GS         C   P L  NG  + T  SF C
Sbjct: 2218 CHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRC 2277

Query: 83   DKDGNITLNPSQT 95
            D D     +P+ T
Sbjct: 2278 DCDEGFQPSPTLT 2290


>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
            isoform 4 [Homo sapiens]
          Length = 2490

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 119  INSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDD---WESGKMNAESVITSSSSHII 175
            I+SS  + +W +GT R  +++  G +  L   SL+      ES  ++   V    +SH+ 
Sbjct: 1211 IDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLG 1270

Query: 176  SQPPGGNSH---SLSLQSQLTASERFQENSSDHSETR 209
             Q    + H   S S+ S+ T  E F +  S+ S+T+
Sbjct: 1271 DQTWQESQHGSPSPSVISKATEKETFTD--SNQSKTK 1305


>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
            isoform 3 [Homo sapiens]
          Length = 2294

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 119  INSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDD---WESGKMNAESVITSSSSHII 175
            I+SS  + +W +GT R  +++  G +  L   SL+      ES  ++   V    +SH+ 
Sbjct: 1020 IDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLG 1079

Query: 176  SQPPGGNSH---SLSLQSQLTASERFQENSSDHSETR 209
             Q    + H   S S+ S+ T  E F +  S+ S+T+
Sbjct: 1080 DQTWQESQHGSPSPSVISKATEKETFTD--SNQSKTK 1114


>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
            isoform 1 [Homo sapiens]
          Length = 2485

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 119  INSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDD---WESGKMNAESVITSSSSHII 175
            I+SS  + +W +GT R  +++  G +  L   SL+      ES  ++   V    +SH+ 
Sbjct: 1211 IDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLG 1270

Query: 176  SQPPGGNSH---SLSLQSQLTASERFQENSSDHSETR 209
             Q    + H   S S+ S+ T  E F +  S+ S+T+
Sbjct: 1271 DQTWQESQHGSPSPSVISKATEKETFTD--SNQSKTK 1305


>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
            2 [Homo sapiens]
          Length = 2466

 Score = 28.1 bits (61), Expect = 8.7
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 119  INSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDD---WESGKMNAESVITSSSSHII 175
            I+SS  + +W +GT R  +++  G +  L   SL+      ES  ++   V    +SH+ 
Sbjct: 1192 IDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLG 1251

Query: 176  SQPPGGNSH---SLSLQSQLTASERFQENSSDHSETR 209
             Q    + H   S S+ S+ T  E F +  S+ S+T+
Sbjct: 1252 DQTWQESQHGSPSPSVISKATEKETFTD--SNQSKTK 1286


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.130    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,662,715
Number of Sequences: 37866
Number of extensions: 457632
Number of successful extensions: 1333
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1309
Number of HSP's gapped (non-prelim): 43
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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