Search of human proteins with 222418791

Search of human proteins with 222418791

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
sapiens]
         (731 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s...  1462   0.0  
gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo s...   843   0.0  
gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo sa...   743   0.0  
gi|40255119 RAS and EF-hand domain containing [Homo sapiens]          245   9e-65
gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]           156   7e-38
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]           152   1e-36
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]          150   3e-36
gi|19923750 RAB3B, member RAS oncogene family [Homo sapiens]          150   4e-36
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa...   150   4e-36
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]            150   4e-36
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]            150   4e-36
gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]           150   4e-36
gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]           150   5e-36
gi|16933567 mel transforming oncogene [Homo sapiens]                  149   9e-36
gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]      149   9e-36
gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]          146   8e-35
gi|150170653 EF-hand calcium binding domain 4A [Homo sapiens]         142   8e-34
gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo sa...   142   1e-33
gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]          142   1e-33
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap...   140   4e-33
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa...   139   7e-33
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]          139   9e-33
gi|19923231 RAB6A, member RAS oncogene family isoform a [Homo sa...   138   2e-32
gi|38679888 RAB6A, member RAS oncogene family isoform b [Homo sa...   137   3e-32
gi|50234889 RAB43 protein [Homo sapiens]                              137   3e-32
gi|5729997 RAB27B, member RAS oncogene family [Homo sapiens]          137   5e-32
gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]         136   8e-32
gi|116812567 RAB25 [Homo sapiens]                                     135   2e-31
gi|21361884 RAB2B protein isoform 1 [Homo sapiens]                    134   3e-31
gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]           134   3e-31

>gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
           sapiens]
          Length = 731

 Score = 1462 bits (3784), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 1   MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ 60
           MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ
Sbjct: 1   MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ 60

Query: 61  TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ 120
           TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ
Sbjct: 61  TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ 120

Query: 121 NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK 180
           NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK
Sbjct: 121 NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK 180

Query: 181 QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM 240
           QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM
Sbjct: 181 QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM 240

Query: 241 EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE 300
           EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE
Sbjct: 241 EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE 300

Query: 301 TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR 360
           TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR
Sbjct: 301 TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR 360

Query: 361 EKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRG 420
           EKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRG
Sbjct: 361 EKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRG 420

Query: 421 ILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRIISVEEDPLP 480
           ILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRIISVEEDPLP
Sbjct: 421 ILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRIISVEEDPLP 480

Query: 481 QLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPS 540
           QLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPS
Sbjct: 481 QLLDGGFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPS 540

Query: 541 APDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWD 600
           APDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWD
Sbjct: 541 APDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWD 600

Query: 601 TAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL 660
           TAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL
Sbjct: 601 TAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL 660

Query: 661 DNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQV 720
           DNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQV
Sbjct: 661 DNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQV 720

Query: 721 GHPAKKKSCCG 731
           GHPAKKKSCCG
Sbjct: 721 GHPAKKKSCCG 731


>gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo
           sapiens]
          Length = 462

 Score =  843 bits (2177), Expect = 0.0
 Identities = 426/436 (97%), Positives = 428/436 (98%), Gaps = 3/436 (0%)

Query: 1   MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ 60
           MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ
Sbjct: 1   MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ 60

Query: 61  TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ 120
           TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ
Sbjct: 61  TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ 120

Query: 121 NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK 180
           NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK
Sbjct: 121 NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK 180

Query: 181 QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM 240
           QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM
Sbjct: 181 QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM 240

Query: 241 EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE 300
           EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE
Sbjct: 241 EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE 300

Query: 301 TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR 360
           TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR
Sbjct: 301 TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR 360

Query: 361 EKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRG 420
           EKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRG
Sbjct: 361 EKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRG 420

Query: 421 ILRSQSEEEEEVFGIP 436
           ILR   + +    GIP
Sbjct: 421 ILRRWPQRDR---GIP 433


>gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo
           sapiens]
          Length = 395

 Score =  743 bits (1917), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ 60
           MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ
Sbjct: 1   MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQ 60

Query: 61  TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ 120
           TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ
Sbjct: 61  TCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQ 120

Query: 121 NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK 180
           NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK
Sbjct: 121 NNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVK 180

Query: 181 QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM 240
           QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM
Sbjct: 181 QLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEM 240

Query: 241 EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE 300
           EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE
Sbjct: 241 EQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHE 300

Query: 301 TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR 360
           TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR
Sbjct: 301 TKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQR 360

Query: 361 EKAGLLKQLDFLR 373
           EKAGLLKQLDFLR
Sbjct: 361 EKAGLLKQLDFLR 373


>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
          Length = 740

 Score =  245 bits (626), Expect = 9e-65
 Identities = 206/745 (27%), Positives = 352/745 (47%), Gaps = 82/745 (11%)

Query: 52  LRKAQEFFQTCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTT 111
           L + +  F  CDA   G + R++ + L  EL +   + E VF  LDAD +G +T QEF  
Sbjct: 10  LARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDGAITFQEFAR 69

Query: 112 GFSHFFFSQNN---------PSQEDAGEQVAQRHEEKVYLSRGDEDLG-----DMGEDEE 157
           GF                  P+  +AG +     E++     GDED         G    
Sbjct: 70  GFLGSLRGGRRRDWGPLDPAPAVSEAGPETHDSEEDE-----GDEDAAAALATSCGPASP 124

Query: 158 AQ-FRMLMDRLGAQ-KVLEDESDVKQLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEK 215
            + ++    RLG + K +  E  V  L+  +   EP L+  +E  +   I +++    E 
Sbjct: 125 GRAWQDFQARLGDEAKFIPREEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQSTEM 184

Query: 216 NELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQ 275
             L  A+KR       ++  L EEM+Q+I++ + +    +  + +    +L ++   +  
Sbjct: 185 ENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVG 244

Query: 276 ELEQLTQKQKRLEGQCTALHH--DKHETKAENTKLKLTNQELARELERTSWELQDAQQQL 333
           +L+   +K ++LE Q   +    D    K +   L + NQ++ ++L      +   Q +L
Sbjct: 245 DLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFLQSEL 304

Query: 334 ESLQQEAC--KLHQEKEMEVYRVTESLQREKAGLLKQLDFLRERNKHLRDERD------- 384
           ++L+ +     L+ E+++E+ R   +   ++  L +Q++ L+  N+ L D  D       
Sbjct: 305 DALKSDYADQSLNTERDLEIIR---AYTEDRNSLERQIEILQTANRKLHDSNDGLRSALE 361

Query: 385 ICFQK-NKAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQ--SEEEEEVFGIP----- 436
             + K N++   N  +   +  + S   IG      G  RS   S  +E+   +      
Sbjct: 362 NSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDPL 421

Query: 437 RRSSLGLSGYP--------LTEEEPGTGEPGPGGPYPRPLRRIISVEED--------PLP 480
           +R++  +   P         T  +P   +      + R  +R   V+E          +P
Sbjct: 422 QRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDVP 481

Query: 481 QLLDG---GFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEES 537
            + D    G E   S    + + S    +G I  +    ++  SP+   V   A  K  S
Sbjct: 482 DIRDEETFGLEDVASVLDWKPQGSVS--EGSIVSSSRKPISALSPQTDLVDDNA--KSFS 537

Query: 538 SPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQ 597
           S  A    +KIV  G++AVGK+SFL R C++ F   ++AT+G+D+++KTL VD  +  LQ
Sbjct: 538 SQKA----YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQ 593

Query: 598 LWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLG 657
           LWDTAGQER+R I + +FRKADGV+++YD+T ++SFL++R W+  +E+A  + VP++L+G
Sbjct: 594 LWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVG 653

Query: 658 NKLD------NEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQ-- 709
           NK D       E ++ VP   GE+LA     +F E SA  G N  E++LHLAR +K++  
Sbjct: 654 NKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTD 713

Query: 710 EDTVREDTIQVGHPAKK----KSCC 730
           +D  R  T   G  +KK    K+CC
Sbjct: 714 KDDSRSITNLTGTNSKKSPQMKNCC 738


>gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]
          Length = 220

 Score =  156 bits (394), Expect = 7e-38
 Identities = 79/176 (44%), Positives = 115/176 (65%)

Query: 534 KEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQ 593
           ++ESS    D +FKI+ +GNS+VGKTSFL R+ +D F+P   +TVGID++VKT+  ++ +
Sbjct: 11  QKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKR 70

Query: 594 VALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPV 653
           + LQ+WDTAGQERYR IT  ++R A G I+MYD+T+++SF +V+ W + ++    D   V
Sbjct: 71  IKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQV 130

Query: 654 LLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQ 709
           LL+GNK D E ER V    G QLA      F+E SA    N K++   L   + E+
Sbjct: 131 LLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEK 186


>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score =  152 bits (384), Expect = 1e-36
 Identities = 70/164 (42%), Positives = 114/164 (69%)

Query: 541 APDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWD 600
           A D LFK++ +G+S VGKT  + RF ED F+    +T+GID++++T++++  ++ LQ+WD
Sbjct: 4   AYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWD 63

Query: 601 TAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL 660
           TAGQER++ IT  ++R A G+I++YD+TD++SF +++ W+ S++E     V  LLLGNK 
Sbjct: 64  TAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKC 123

Query: 661 DNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLAR 704
           D E +R+V +   ++LA E+ + F+E SA S  N  E+   LAR
Sbjct: 124 DMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLAR 167


>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score =  150 bits (380), Expect = 3e-36
 Identities = 74/194 (38%), Positives = 117/194 (60%), Gaps = 6/194 (3%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTA 602
           D LFKIV +GN+ VGKT  +RRF +  F PG  AT+G+D+ +KT+ ++  +V LQ+WDTA
Sbjct: 7   DFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTA 66

Query: 603 GQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDN 662
           GQER+R ITQ ++R A+ +I+ YD+T ++SF  +  WL  +E+   ++V  +L+GNK+D 
Sbjct: 67  GQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDL 126

Query: 663 EKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLA-RFLKEQEDTVREDTIQVG 721
            + REV +   E+ +   ++ + E SA    N ++  L LA R + E       + +   
Sbjct: 127 AERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSP 186

Query: 722 HPAKKKS-----CC 730
            P + KS     CC
Sbjct: 187 LPGEGKSISYLTCC 200


>gi|19923750 RAB3B, member RAS oncogene family [Homo sapiens]
          Length = 219

 Score =  150 bits (379), Expect = 4e-36
 Identities = 76/188 (40%), Positives = 119/188 (63%), Gaps = 1/188 (0%)

Query: 535 EESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQV 594
           +++S    D +FK++ +GNS+VGKTSFL R+ +D F+P   +TVGID++VKT+     +V
Sbjct: 12  KDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRV 71

Query: 595 ALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVL 654
            LQ+WDTAGQERYR IT  ++R A G I+MYD+T+++SF +V+ W + ++    D   V+
Sbjct: 72  KLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVI 131

Query: 655 LLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLA-RFLKEQEDTV 713
           L+GNK D E+ER VP   G+ LA +    F+E SA    + +++   L      +  D++
Sbjct: 132 LVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSL 191

Query: 714 REDTIQVG 721
             D   +G
Sbjct: 192 DTDPSMLG 199


>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
           family [Homo sapiens]
          Length = 327

 Score =  150 bits (379), Expect = 4e-36
 Identities = 70/164 (42%), Positives = 112/164 (68%)

Query: 541 APDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWD 600
           A D LFK++ +G+S VGKT  + RF ED F+    +T+GID++++T++++  ++ LQ+WD
Sbjct: 128 AYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWD 187

Query: 601 TAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL 660
           TAGQER++ IT  ++R A G+I+ YD+TD++SF +++ W+ S+ E     V  LLLGNK 
Sbjct: 188 TAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKC 247

Query: 661 DNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLAR 704
           D E +R+V +   ++LA E+ + F+E SA S  N  E+   LAR
Sbjct: 248 DMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLAR 291


>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score =  150 bits (379), Expect = 4e-36
 Identities = 70/164 (42%), Positives = 112/164 (68%)

Query: 541 APDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWD 600
           A D LFK++ +G+S VGKT  + RF ED F+    +T+GID++++T++++  ++ LQ+WD
Sbjct: 128 AYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWD 187

Query: 601 TAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL 660
           TAGQER++ IT  ++R A G+I+ YD+TD++SF +++ W+ S+ E     V  LLLGNK 
Sbjct: 188 TAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKC 247

Query: 661 DNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLAR 704
           D E +R+V +   ++LA E+ + F+E SA S  N  E+   LAR
Sbjct: 248 DMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLAR 291


>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score =  150 bits (379), Expect = 4e-36
 Identities = 70/164 (42%), Positives = 112/164 (68%)

Query: 541 APDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWD 600
           A D LFK++ +G+S VGKT  + RF ED F+    +T+GID++++T++++  ++ LQ+WD
Sbjct: 128 AYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWD 187

Query: 601 TAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKL 660
           TAGQER++ IT  ++R A G+I+ YD+TD++SF +++ W+ S+ E     V  LLLGNK 
Sbjct: 188 TAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSIMENASAGVEHLLLGNKC 247

Query: 661 DNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLAR 704
           D E +R+V +   ++LA E+ + F+E SA S  N  E+   LAR
Sbjct: 248 DMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLAR 291


>gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]
          Length = 207

 Score =  150 bits (379), Expect = 4e-36
 Identities = 70/179 (39%), Positives = 117/179 (65%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTA 602
           D LFK++ +G+S VGKT  L RF ED F+    +T+GID++++T+ +D  ++ LQ+WDTA
Sbjct: 6   DYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTA 65

Query: 603 GQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDN 662
           GQER+R IT  ++R A G++++YD+T+++SF +++ W+ ++EE     V  ++LGNK D 
Sbjct: 66  GQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDM 125

Query: 663 EKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQVG 721
             +R+V +  GE+LA +  + F E SA S  N +E+   LAR +  + +    D+   G
Sbjct: 126 NDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAG 184


>gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]
          Length = 219

 Score =  150 bits (378), Expect = 5e-36
 Identities = 75/183 (40%), Positives = 114/183 (62%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTA 602
           D +FK++ +GNS+VGKTSFL R+ +D F+P   +TVGID++VKT+   + ++ LQ+WDTA
Sbjct: 20  DYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTA 79

Query: 603 GQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDN 662
           GQERYR IT  ++R A G ++MYD+ +++SF +V+ W + ++    D   V+L+GNK D 
Sbjct: 80  GQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDL 139

Query: 663 EKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQVGH 722
           E ER VP   G +LA +    F+E SA    N K+    L   + E+ +   E +   G 
Sbjct: 140 EDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEPSSSSGS 199

Query: 723 PAK 725
             K
Sbjct: 200 NGK 202


>gi|16933567 mel transforming oncogene [Homo sapiens]
          Length = 207

 Score =  149 bits (376), Expect = 9e-36
 Identities = 69/169 (40%), Positives = 114/169 (67%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTA 602
           D LFK++ +G+S VGKT  L RF ED F+    +T+GID++++T+ +D  ++ LQ+WDTA
Sbjct: 6   DYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTA 65

Query: 603 GQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDN 662
           GQER+R IT  ++R A G++++YD+T+++SF ++R W+ ++EE     V  ++LGNK D 
Sbjct: 66  GQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDV 125

Query: 663 EKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQED 711
             +R+V +  GE+LA +  + F E SA +  N + +   LAR +K + D
Sbjct: 126 NDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMD 174


>gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]
          Length = 200

 Score =  149 bits (376), Expect = 9e-36
 Identities = 70/177 (39%), Positives = 119/177 (67%), Gaps = 6/177 (3%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTA 602
           D LFK++ +G+S VGKT  L RF +D F+    +T+GID+++KT+ +   ++ LQ+WDTA
Sbjct: 7   DLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTA 66

Query: 603 GQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDN 662
           GQER+  IT  ++R A G++++YD+T+ +SF ++ +WL +++E   + V  +LLGNK D 
Sbjct: 67  GQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDM 126

Query: 663 EKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQ 719
           + +R VP+G G Q+A E+ + F+E SA +  N +++ L LA      ED +R+  ++
Sbjct: 127 DDKRVVPKGKGGQIAREHGIRFFETSAKANINIEKAFLTLA------EDILRKTPVK 177


>gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]
          Length = 227

 Score =  146 bits (368), Expect = 8e-35
 Identities = 71/169 (42%), Positives = 110/169 (65%)

Query: 534 KEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQ 593
           +++SS    D +FK++ +GNS+VGKTSFL R+ +D F+    +TVGID++VKT+  +  +
Sbjct: 19  QKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKR 78

Query: 594 VALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPV 653
           + LQ+WDTAGQERYR IT  ++R A G I+MYD+T+++SF +V+ W + ++    D   V
Sbjct: 79  IKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQV 138

Query: 654 LLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHL 702
           +L+GNK D E ER +    G+ L  +    F+E SA    N K++   L
Sbjct: 139 ILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERL 187


>gi|150170653 EF-hand calcium binding domain 4A [Homo sapiens]
          Length = 294

 Score =  142 bits (359), Expect = 8e-34
 Identities = 92/276 (33%), Positives = 153/276 (55%), Gaps = 14/276 (5%)

Query: 37  EQKETQEQTSG-QLVMLRKAQEFFQTCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDA 95
           E+ E +  ++G +  +L +A+E F  CD E KGFI + D+Q L  +LPL+ E+LE VF++
Sbjct: 15  EEGELEGGSAGPRAAILEQAEELFLLCDKEAKGFITKHDLQGLQSDLPLTPEQLEAVFES 74

Query: 96  LDADGNGYLTPQEFTTGFSHFFFSQNNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMG-- 153
           LD    G+LT +EF  G   F    +             R  E+ + S G +  G  G  
Sbjct: 75  LDRAHTGFLTAREFCLGLGMFVGVASAQGANPC------RTPEETFESGGLDVQGTAGSL 128

Query: 154 ---EDEEAQFRMLMDRLGAQKVLEDESDVKQLWLQLKKEEPHLLSNFEDFLTRIISQLQE 210
              E+EE +F  ++++LG   VL  +  V+ LW +L++E P LL +FED L R  + L+E
Sbjct: 129 DEEEEEEERFHTVLEQLGVAPVLGKQRAVRTLWARLQRERPELLGSFEDVLIRASACLEE 188

Query: 211 AHEEKNELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERFQARSQELEQKL 270
           A  E++ LE AL+R+ + ++ E++ LYEE E Q++ +  +   ++  R + RS+ LE +L
Sbjct: 189 AARERDGLEQALRRRESEHEREVRALYEETE-QLREQSRRPPSQNFARGERRSR-LELEL 246

Query: 271 LCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENT 306
             +EQ+LE+   +Q+   G+    H ++    A  T
Sbjct: 247 QSREQDLERAGLRQRERRGRRLQEHAERESQPATAT 282


>gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo
           sapiens]
          Length = 223

 Score =  142 bits (357), Expect = 1e-33
 Identities = 82/219 (37%), Positives = 124/219 (56%), Gaps = 8/219 (3%)

Query: 520 TSPRGQPVGKEALCKEESSPSAP--DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPG-MAA 576
           T   G    ++    E S P +P  D   K++ +G++ VGKT FL +F +  F  G   A
Sbjct: 2   TGTPGAVATRDGEAPERSPPCSPSYDLTGKVMLLGDTGVGKTCFLIQFKDGAFLSGTFIA 61

Query: 577 TVGIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSV 636
           TVGID+R K + VD  +V LQ+WDTAGQER+R +T  ++R A  ++++YD+T+K SF ++
Sbjct: 62  TVGIDFRNKVVTVDGVRVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITNKSSFDNI 121

Query: 637 RRWLSSVEEAVGDRVPVLLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTK 696
           R WL+ + E     V ++LLGNK D   ER +    GE LA E  + F E SA +G N +
Sbjct: 122 RAWLTEIHEYAQRDVVIMLLGNKADMSSERVIRSEDGETLAREYGVPFLETSAKTGMNVE 181

Query: 697 ESLLHLARFLK-----EQEDTVREDTIQVGHPAKKKSCC 730
            + L +A+ LK     + ++   +    V    K+ SCC
Sbjct: 182 LAFLAIAKELKYRAGHQADEPSFQIRDYVESQKKRSSCC 220


>gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]
          Length = 256

 Score =  142 bits (357), Expect = 1e-33
 Identities = 75/168 (44%), Positives = 110/168 (65%), Gaps = 1/168 (0%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPG-MAATVGIDYRVKTLNVDNSQVALQLWDT 601
           D  FK++ VG+S VGKT  L RF +  F  G   +TVGID+R K L+VD  +V LQ+WDT
Sbjct: 61  DVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQMWDT 120

Query: 602 AGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLD 661
           AGQER+R +T  ++R A  ++++YD+T+K SF +++ WL+ + E     V ++LLGNK+D
Sbjct: 121 AGQERFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVD 180

Query: 662 NEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQ 709
           +  ER V R  GE+LA E  L F E SA +G N   +   +A+ LK++
Sbjct: 181 SAHERVVKREDGEKLAKEYGLPFMETSAKTGLNVDLAFTAIAKELKQR 228


>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
           sapiens]
          Length = 205

 Score =  140 bits (353), Expect = 4e-33
 Identities = 62/167 (37%), Positives = 109/167 (65%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTA 602
           D LFK++ +G+S VGK+  L RF +D ++    +T+G+D++++T+ +D   + LQ+WDTA
Sbjct: 9   DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTA 68

Query: 603 GQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDN 662
           GQER+R IT  ++R A G+IV+YD+TD++SF +V++WL  ++    + V  LL+GNK D 
Sbjct: 69  GQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDL 128

Query: 663 EKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQ 709
             ++ V     ++ A    + F E SA +  N ++S + +A  +K++
Sbjct: 129 TTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKR 175


>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
           sapiens]
          Length = 216

 Score =  139 bits (351), Expect = 7e-33
 Identities = 77/192 (40%), Positives = 115/192 (59%), Gaps = 6/192 (3%)

Query: 545 LFKIVFVGNSAVGKTSFLRRFCEDRFSPG-MAATVGIDYRVKTLNVDNSQVALQLWDTAG 603
           L K + VG+S VGKTS L +F + +F PG  +ATVGI +  K + VD  +V LQ+WDTAG
Sbjct: 22  LHKTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTNKVVTVDGVRVKLQIWDTAG 81

Query: 604 QERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDNE 663
           QER+R +T  ++R A  ++++YD+T+K SF ++R WL+ + E     V ++LLGNK D  
Sbjct: 82  QERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADMS 141

Query: 664 KEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLK-----EQEDTVREDTI 718
            ER +    GE LA E  + F E SA +G N + + L +A+ LK     + ++   +   
Sbjct: 142 SERVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKELKYRAGHQADEPSFQIRD 201

Query: 719 QVGHPAKKKSCC 730
            V    K+ SCC
Sbjct: 202 YVESQKKRSSCC 213


>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score =  139 bits (350), Expect = 9e-33
 Identities = 60/167 (35%), Positives = 109/167 (65%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTA 602
           D LFK++ +G+S VGK+  L RF +D ++    +T+G+D++++T+ +D   + LQ+WDTA
Sbjct: 6   DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTA 65

Query: 603 GQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDN 662
           GQER+R IT  ++R A G+IV+YD+TD++S+ +V++WL  ++    + V  LL+GNK D 
Sbjct: 66  GQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDL 125

Query: 663 EKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQ 709
             ++ V     ++ A    + F E SA +  N +++ + +A  +K++
Sbjct: 126 TTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKR 172


>gi|19923231 RAB6A, member RAS oncogene family isoform a [Homo
           sapiens]
          Length = 208

 Score =  138 bits (347), Expect = 2e-32
 Identities = 72/182 (39%), Positives = 108/182 (59%), Gaps = 3/182 (1%)

Query: 542 PDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDT 601
           P R FK+VF+G  +VGKTS + RF  D F     AT+GID+  KT+ +++  + LQLWDT
Sbjct: 10  PLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDT 69

Query: 602 AGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLD 661
           AGQER+R +   + R +   +V+YD+T+  SF    +W+  V    G  V ++L+GNK D
Sbjct: 70  AGQERFRSLIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTD 129

Query: 662 NEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFL---KEQEDTVREDTI 718
              +R+V    GE+ A E N++F E SA +G+N K+    +A  L   +  +D  RED I
Sbjct: 130 LADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMI 189

Query: 719 QV 720
            +
Sbjct: 190 DI 191


>gi|38679888 RAB6A, member RAS oncogene family isoform b [Homo
           sapiens]
          Length = 208

 Score =  137 bits (346), Expect = 3e-32
 Identities = 73/182 (40%), Positives = 108/182 (59%), Gaps = 3/182 (1%)

Query: 542 PDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDT 601
           P R FK+VF+G  +VGKTS + RF  D F     AT+GID+  KT+ +++  V LQLWDT
Sbjct: 10  PLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDT 69

Query: 602 AGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLD 661
           AGQER+R +   + R +   +V+YD+T+  SF    +W+  V    G  V ++L+GNK D
Sbjct: 70  AGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTD 129

Query: 662 NEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFL---KEQEDTVREDTI 718
              +R+V    GE+ A E N++F E SA +G+N K+    +A  L   +  +D  RED I
Sbjct: 130 LADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMI 189

Query: 719 QV 720
            +
Sbjct: 190 DI 191


>gi|50234889 RAB43 protein [Homo sapiens]
          Length = 212

 Score =  137 bits (346), Expect = 3e-32
 Identities = 69/162 (42%), Positives = 102/162 (62%), Gaps = 1/162 (0%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTA 602
           D LFK+V VG+++VGKT  ++RF    FS    +T+G+D+ +KTL +   +V LQ+WDTA
Sbjct: 16  DFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQIWDTA 75

Query: 603 GQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDN 662
           GQER+R ITQ ++R A+G I+ YD+T + SFLSV  W+  V +  G  +  LL+GNK D 
Sbjct: 76  GQERFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDL 135

Query: 663 EKEREVPRGLGEQLATENNLI-FYECSAYSGHNTKESLLHLA 703
            + REV     + LA   +++   E SA    N +E+ L +A
Sbjct: 136 SELREVSLAEAQSLAEHYDILCAIETSAKDSSNVEEAFLRVA 177


>gi|5729997 RAB27B, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score =  137 bits (344), Expect = 5e-32
 Identities = 86/213 (40%), Positives = 125/213 (58%), Gaps = 26/213 (12%)

Query: 543 DRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQ--------- 593
           D L K++ +G+S VGKT+FL R+ +++F+P    TVGID+R K + V N+Q         
Sbjct: 7   DYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRV-VYNAQGPNGSSGKA 65

Query: 594 --VALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVE-EAVGDR 650
             V LQLWDTAGQER+R +T  FFR A G ++M+DLT +QSFL+VR W+S ++  A  + 
Sbjct: 66  FKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCEN 125

Query: 651 VPVLLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTK---ESLLHLARFLK 707
             ++L+GNK D   +REV      +LA +  + ++E SA +G N +   E+LL L     
Sbjct: 126 PDIVLIGNKADLPDQREVNERQARELADKYGIPYFETSAATGQNVEKAVETLLDLIMKRM 185

Query: 708 EQ--EDTVREDTIQVGH--------PAKKKSCC 730
           EQ  E T   DT+  G+        P +KK  C
Sbjct: 186 EQCVEKTQIPDTVNGGNSGNLDGEKPPEKKCIC 218


>gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]
          Length = 244

 Score =  136 bits (342), Expect = 8e-32
 Identities = 62/170 (36%), Positives = 104/170 (61%), Gaps = 1/170 (0%)

Query: 534 KEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQ 593
           + +  P   D   +++ +G+  VGKTS + RF +D F     +TVG+D+++KT+ +   +
Sbjct: 31  RRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKK 90

Query: 594 VALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPV 653
           + LQ+WDTAGQER+  IT  ++R A G+I++YD+T K++F  + +W+  +++   +   +
Sbjct: 91  IRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAEL 150

Query: 654 LLLGNKLDNEKEREVPRGLGEQLATE-NNLIFYECSAYSGHNTKESLLHL 702
           LL+GNKLD E +RE+ R  GE+ A +   + F E SA    N  E  L L
Sbjct: 151 LLVGNKLDCETDREITRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKL 200


>gi|116812567 RAB25 [Homo sapiens]
          Length = 213

 Score =  135 bits (339), Expect = 2e-31
 Identities = 70/199 (35%), Positives = 114/199 (57%), Gaps = 13/199 (6%)

Query: 545 LFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQ 604
           +FK+V +G S VGKT+ L RF  + FS     T+G+++  +T+ +  + V  Q+WDTAG 
Sbjct: 12  VFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGL 71

Query: 605 ERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDNEK 664
           ERYR IT  ++R A G ++++DLT  Q++  V RWL  + +     + V+L+GNK D  +
Sbjct: 72  ERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQ 131

Query: 665 EREVPRGLGEQLATENNLIFYECSAYSGHNTK---ESLLH--LARFLKEQEDTVREDTIQ 719
            REVP       A  N L+F E SA    N +   E++L    A+  K++++++R + I 
Sbjct: 132 AREVPTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQRQNSIRTNAIT 191

Query: 720 VGH--------PAKKKSCC 730
           +G         P +K++CC
Sbjct: 192 LGSAQAGQEPGPGEKRACC 210


>gi|21361884 RAB2B protein isoform 1 [Homo sapiens]
          Length = 216

 Score =  134 bits (337), Expect = 3e-31
 Identities = 60/160 (37%), Positives = 101/160 (63%)

Query: 545 LFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQ 604
           LFK + +G++ VGK+  L +F + RF P    T+G+++  + +N+D  Q+ LQ+WDTAGQ
Sbjct: 6   LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQ 65

Query: 605 ERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDNEK 664
           E +R IT+ ++R A G +++YD+T +++F  +  WL    +     + ++L+GNK D E 
Sbjct: 66  ESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLES 125

Query: 665 EREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLAR 704
            R+V R  GE  A E+ LIF E SA +  N +E+ ++ A+
Sbjct: 126 RRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAK 165


>gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]
          Length = 212

 Score =  134 bits (337), Expect = 3e-31
 Identities = 63/180 (35%), Positives = 107/180 (59%), Gaps = 3/180 (1%)

Query: 545 LFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQ 604
           LFK + +G++ VGK+  L +F + RF P    T+G+++  + + +D  Q+ LQ+WDTAGQ
Sbjct: 6   LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQ 65

Query: 605 ERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDNEK 664
           E +R IT+ ++R A G +++YD+T + +F  +  WL    +     + ++L+GNK D E 
Sbjct: 66  ESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLES 125

Query: 665 EREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQVGHPA 724
            REV +  GE  A E+ LIF E SA +  N +E+ ++ A   KE  + ++E    + + A
Sbjct: 126 RREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTA---KEIYEKIQEGVFDINNEA 182


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,698,625
Number of Sequences: 37866
Number of extensions: 1680066
Number of successful extensions: 14672
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 487
Number of HSP's successfully gapped in prelim test: 1151
Number of HSP's that attempted gapping in prelim test: 7497
Number of HSP's gapped (non-prelim): 4562
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.