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Search of human proteins with 222418637
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
(750 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 1523 0.0
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 1203 0.0
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 1125 0.0
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 903 0.0
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 875 0.0
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 831 0.0
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 497 e-140
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 494 e-139
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 383 e-106
gi|239750781 PREDICTED: golgi autoantigen, golgin subfamily a-li... 323 3e-88
gi|148746195 trichohyalin [Homo sapiens] 285 1e-76
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 251 2e-66
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 235 1e-61
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 228 1e-59
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 226 6e-59
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 225 1e-58
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 224 3e-58
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 222 9e-58
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 216 8e-56
gi|221219020 NYD-SP11 protein [Homo sapiens] 201 2e-51
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 174 2e-43
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 174 2e-43
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 169 1e-41
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 166 7e-41
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 166 1e-40
gi|21735548 centrosomal protein 2 [Homo sapiens] 151 2e-36
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 150 3e-36
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 150 3e-36
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 150 3e-36
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 150 3e-36
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 1523 bits (3944), Expect = 0.0
Identities = 750/750 (100%), Positives = 750/750 (100%)
Query: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL
Sbjct: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
Query: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA
Sbjct: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
Query: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA
Sbjct: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI
Sbjct: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
Query: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
Query: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Query: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
Query: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE
Sbjct: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
Query: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
Query: 721 EQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
EQEEKMRRQEEKMWEQEVRLRQQEEKMQEH
Sbjct: 721 EQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 1203 bits (3112), Expect = 0.0
Identities = 609/680 (89%), Positives = 634/680 (93%), Gaps = 19/680 (2%)
Query: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL
Sbjct: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
Query: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA
Sbjct: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
Query: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA
Sbjct: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI
Sbjct: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
Query: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM RRQEEMMWE
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM--------------RRQEEMMWE 346
Query: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
KEEKMRRQEEMMWEKEEKMRR EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 406
Query: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 466
Query: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
QEEKI EQEEIWRQKEKMHEQ EKIRKQEEKVWRQEEK+ +QEEKIREQEEKMWRQEEKI
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQ-EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
Query: 541 REQEEMWRE-EEKMHEQEKIW--EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
REQEE RE EEK+ EQE++ +EEK EQE+KM +++EK+R QEEK+ QEEKIREQ+
Sbjct: 526 REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-QEQEKMRRQEEKIREQEEKIREQK 584
Query: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 657
EK +EQEEK+W+QEEKIREQEE +QEQEEK+ EQEEK+ EQEE QEQEEKM QEEKM
Sbjct: 585 EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 644
Query: 658 EQEEKMQEQEETMWRQEEKI 677
EQE ++++QEE M +E +
Sbjct: 645 EQEVRLRQQEEKMQEHQEHL 664
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 1125 bits (2909), Expect = 0.0
Identities = 581/678 (85%), Positives = 605/678 (89%), Gaps = 44/678 (6%)
Query: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
MLMWPQPHLP THPHLPTHPHLPTHPMMSKETRQSKL
Sbjct: 86 MLMWPQPHLP------------------------THPHLPTHPHLPTHPMMSKETRQSKL 121
Query: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA
Sbjct: 122 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 181
Query: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA
Sbjct: 182 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 241
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI
Sbjct: 242 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 301
Query: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE
Sbjct: 302 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 361
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM RRQEEMMWE
Sbjct: 362 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM--------------RRQEEMMWE 407
Query: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR
Sbjct: 408 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 467
Query: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
EQEKRQEQEAKMWRQEEKIREQEEKIREQE+KMWRQEEKIHEQEKIREEEKRQEQEEMWR
Sbjct: 468 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR 527
Query: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
QEEKI EQEEIWRQKEK+HEQEEKIRKQEEK+WRQEEK+ +QEEKIREQEEK+WRQEEKI
Sbjct: 528 QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 541 REQEEMWRE-EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599
REQEE RE EEK+ EQ EE QEQE+KM QEEK+ EQEEK+ QEEK+R QEEK
Sbjct: 588 REQEEKIREQEEKIREQ-----EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659
+EQE+K+ +QEEKIREQEE +QEQEEK+ EQEEK+ EQEE QEQEEKM QEEKM EQ
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Query: 660 EEKMQEQEETMWRQEEKI 677
E ++++QEE M +E +
Sbjct: 703 EVRLRQQEEKMQEHQEHL 720
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 903 bits (2334), Expect = 0.0
Identities = 486/601 (80%), Positives = 524/601 (87%), Gaps = 38/601 (6%)
Query: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
MLMWPQPHLPTH PHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL
Sbjct: 1 MLMWPQPHLPTH------------PHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 48
Query: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA
Sbjct: 49 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 108
Query: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
LRRELEAQV TIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA
Sbjct: 109 LRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 168
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI
Sbjct: 169 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 228
Query: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
KMWRQ EEKIQE+EEKI+EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE
Sbjct: 289 KMWRQ-------EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK-RQEEEKI 419
KEEK+R EE M E +EK+R QEE ++EEKIRE E++ ++ K+ QEEK R++EEKI
Sbjct: 342 KEEKIRELEEKMHE-QEKIREQEEKR-QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 399
Query: 420 REQEK-RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE-KIRE-EEKRQEQE 476
REQE+ QEQE KM QEEK+ EQEE+++EQE+KM RQEEKI EQE KIRE EEK +EQE
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459
Query: 477 EMWR-QEEKIHEQE-EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
EM + QEEK+ EQE ++ Q+ KM EQEEK+R+QEEK+ QE+KIREQEEKIREQEE M
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519
Query: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
QEEK MW +EEKM EQ EEK QEQE+KM RQEEK+REQE ++ +QEEK++
Sbjct: 520 EQEEK------MWEQEEKMCEQ-----EEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Query: 595 E 595
E
Sbjct: 569 E 569
Score = 446 bits (1148), Expect = e-125
Identities = 239/396 (60%), Positives = 300/396 (75%), Gaps = 19/396 (4%)
Query: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK--------- 424
+K++ R EE+ E++ EL E+++E+ K QE+ ++ E EK
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234
Query: 425 --RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 482
R+ + AK+ +++++ + + + ++ + + + + E+ ++ +Q++E+MWRQE
Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 294
Query: 483 EKIHEQEE-IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
EKI E+EE I Q+EK+ EQEEK+R+QEE +W +EEK+R QEE + E+EEK+ EEK+
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354
Query: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
EQE++ +EEK E+EKI E+EKRQEQE KMWRQEEKIREQEEK+ QEE ++EQEEK
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 602 EQEEKMWKQEE-------KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 654
EQEEKMW+QEE K+R QEEKI+EQE+KIREQEEKIREQEEM QEQEEKMGEQE
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 655 KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714
KMCEQE KMQEQEE M RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 534
Query: 715 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
QEEKMQEQEEKMRRQEEKM EQEVRLRQQEEKMQEH
Sbjct: 535 QEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 355 bits (911), Expect = 9e-98
Identities = 213/473 (45%), Positives = 323/473 (68%), Gaps = 24/473 (5%)
Query: 245 KELKRKLERAKLLLPQQ-QLQAE---ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
+EL+ +++ ++L Q+ +LQ + H K+L+ + L +++ ++ + +Q
Sbjct: 111 RELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALS 170
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
+ Q++K + E++ ++ + + + + +E+++ + + EK + + ++ +
Sbjct: 171 AVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQL 230
Query: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
++++R+ E+ + + Q+++ E + +EL+ K++ Q E+ + ++
Sbjct: 231 NVKELKRK----LERAKLLLPQQQLQAEADHLGKELQSV---SAKLQAQVEENELWNRLN 283
Query: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI---REEEKRQEQEE 477
+Q QE KMWRQEEKI+E+EEKI+EQE+K+ QEEK+ QE++ +EE+ R+++E
Sbjct: 284 QQ-----QEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 338
Query: 478 MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE 537
MW +EEKI E EE ++EK+ EQEEK R++EEK+ R++EK +EQE K+ QEEK+ QE
Sbjct: 339 MWEKEEKIRELEEKMHEQEKIREQEEK-RQEEEKI-REQEKRQEQEAKMWRQEEKIREQE 396
Query: 538 EKIREQEEMWRE-EEKMHEQ-EKIWE-EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
EKIREQEEM +E EEKM EQ EK+WE EE+ QEQE+KM RQEEKIREQE+K+ QEEKIR
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 654
EQEE QEQEEKM +QE K+ EQE K+QEQEEK+R QEEKIREQE+ +EQEEK+ EQEE
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 655 KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707
M EQEEKM EQEE M QEEK++EQE+K+R QEEK+REQE +++QEEKM E
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 875 bits (2262), Expect = 0.0
Identities = 474/781 (60%), Positives = 597/781 (76%), Gaps = 75/781 (9%)
Query: 3 MWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAE 62
MWPQPHLP HPMMS++TRQ+KLAE
Sbjct: 1 MWPQPHLP------------------------------------PHPMMSEKTRQNKLAE 24
Query: 63 AKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALR 122
AK++ TD+ VGT A+DTKKKKINNGTNPETTTS GCHSPEDE+KASHQHQEALR
Sbjct: 25 AKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALR 84
Query: 123 RELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE----GEARDLISRLHDSWKFAGELE 178
RE+EAQ HTIRILTCQKTEL+ ALYYSQ A ++ E GE++DL RLH SW FAGEL+
Sbjct: 85 REIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQ 144
Query: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238
+ALSAV+T KKADRYIEELTKERDALSLELYRNTIT+EELK+KNA+LQEKL+L ESEKS
Sbjct: 145 RALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKS 204
Query: 239 EIQLNVKELKRKLERAKLLLPQQQ---LQAEADHLGKELQSVSAKLQAQVEENELW---N 292
EIQLNVKELKRKLERAK LLPQ Q LQ E +EL+ K++ Q E ++W
Sbjct: 205 EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMWRQEE 262
Query: 293 RLNQQ------QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 346
RL +Q QEEKM RQE++++E E++++EQE+++REQ +K+REQEE+M+ QEE MWE
Sbjct: 263 RLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ-KKLREQEEQMQEQEEKMWE 321
Query: 347 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 406
+EEKMR QEE MW +EE++ QE+ M E+E+KMR QEE MWE++E++RE EE+M EQEK+
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
Query: 407 REQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465
EQEEK QEEE+IRE+EK+ +E+E M QEEK+++QEE + EQE+K W+Q+ ++EK
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Query: 466 IREEEKRQEQEE-MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEE 524
+ E+EK QEQEE +W QEEKI +QEE+W Q++KM Q EK+R+QE+++W QEEK+R+QE+
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEKMRDQEQ 500
Query: 525 KIREQEEKMWRQEEKIREQEEMWREEEKMHEQ-EKIWEEEKRQEQEDKMWRQEEKIREQE 583
K+ +QEE+MW Q+E++RE+EE RE++KM +Q EK+ EE+K QEQE K W QEEK+RE E
Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-E 559
Query: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE--M 641
E++ +E+K+RE+EE +EQEEKM +QEEK+REQEEK+ EQEEK++EQEEK+ EQEE
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Query: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
QE+E+KM EQEE M EQEEKMQEQEE MW QEEK+REQE+K+REQEEK++ QEE M+EQ
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 702 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW-------------EQEVRLRQQEEKMQ 748
EEKM QEEKM EQEEKM+ QEEKM QEEKMW E+E R+R Q+EKMQ
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Query: 749 E 749
E
Sbjct: 740 E 740
Score = 269 bits (688), Expect = 6e-72
Identities = 180/466 (38%), Positives = 291/466 (62%), Gaps = 41/466 (8%)
Query: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTEL---QMALYYSQHAVKQLEGEARDLISR 166
EQK + +E ++ + E + Q+ ++ + L+ + +++ E + RD R
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 167 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 226
+ W+ L + + Q+K ++ EE +E + + + +E ++E+ K+
Sbjct: 361 M---WEQDERLREKEERMREQEKMWEQ--EEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 227 QEKLQLV--ESEKSEIQLNVKELKRKL--------ERAKLLLPQQQLQAEADHLGKELQS 276
Q++ + + + EK Q + E K KL + K+ +++++ + + G+E +
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE-KK 474
Query: 277 VSAKLQAQVEENELWNRLNQQ--QEEKMWRQEEKIQEWEEKIQEQEEKIRE------QEE 328
+ + + + +E+++W + + QE+KMW QEE++ E +E+++E+EE++RE QEE
Sbjct: 475 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534
Query: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
K+RE E+K + QE+ W++EEKM R+EE M E+E+KMR +EEMM E+EEKM+ QEE M E
Sbjct: 535 KMRE-EKKTQEQEKKTWDQEEKM-REEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 389 KEEKIRELEEKMHEQ-EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
+EEK+ E EEKM EQ EK+ EQEEK E+E E++K QEQE MW QEEK++EQEEK+
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQE---EEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Query: 448 EQEKKMWRQEEKIHEQEKI---REEEKRQEQEEMWRQEEKIHEQEEIWR-QKEKMHEQEE 503
EQE+KM QEEK+ EQE+ +EE+ R+++E+M QEEK+ EQEE R Q+EKM QEE
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEE 709
Query: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549
K+ QEEK+W QEE +RE+EE+IR+Q+EKM +E++ E EE E
Sbjct: 710 KMWGQEEKMWGQEE-MREKEERIRDQKEKM---QERLPEHEERCSE 751
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 831 bits (2147), Expect = 0.0
Identities = 471/854 (55%), Positives = 593/854 (69%), Gaps = 151/854 (17%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
PHLP HPMMS++TRQ+KLAEAK++ TD+ VGT A+DTKKKKIN+GTNPETTTSG
Sbjct: 5 PHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPETTTSG 64
Query: 103 GCHSPED----------EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHA 152
GCHSPED E+KASHQHQEALRRE+EAQ HTIRILTCQKTEL+ ALYYSQ A
Sbjct: 65 GCHSPEDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDA 124
Query: 153 VKQLE--------------------------------GEARDLISRLHDSWKFAGELEQA 180
++ E GE++DL RLH SW FAGEL++A
Sbjct: 125 ARKFEDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRA 184
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAV+T+ KKADRYIEELTKERDALSLELYRNTIT+EELK+KNA+LQEKL L ESEKSEI
Sbjct: 185 LSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEI 244
Query: 241 QLNVKELKRKLERAKLLLPQQQ---LQAEADHLGKELQSVSAKLQAQVEENELW---NRL 294
QLNVKELKRKLERAK LLPQ Q LQ E +EL+ K++ Q E ++W RL
Sbjct: 245 QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMWRQEERL 302
Query: 295 NQQ------QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
+Q QEEKMWRQE++++E E++++EQE+++REQ+E +REQEE+M+ QEE MWE+E
Sbjct: 303 REQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE-LREQEEQMQEQEEKMWEQE 361
Query: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
EKMR QEE MW +EE++ QE+ M E+E+KMR QEE MWE++E++RE EE+M EQEK+ E
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421
Query: 409 QEEKRQEEEKIREQEKR--------------QEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Q EK +EE+K++EQEK+ +E+E KM +EE +REQEEK+++QE+ MW
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 481
Query: 455 RQEEKIHEQ-------EKIREEEKRQEQEE-MWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
QEEK +Q EK+ E+EK QEQEE +W QEEKI +QEE+W Q++KM Q EK+R
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMR 540
Query: 507 KQEEKVWRQEEKIREQEEKI-----------REQEEKMWRQEEKIREQEEMWREEEKMHE 555
+QE+++W QEEK+R+QE+K+ +EQE+K W QEEK+RE+E M E+KM E
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 556 QEKIW---------EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR------ 600
+E++ +EEK QEQE+KMW QEEK++EQEEK+W QEEK+ EQEEK
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 601 QEQEEKMWKQE-----EKIREQEEKIQEQ----------------------EEKIREQEE 633
EQ+EK+W+ E EK++EQEEKI EQ EE +RE+E+
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK 720
Query: 634 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK----------- 682
K+RE+EEM +EQEEKM EQEEKM EQEE+M EQEE MW QEEK+ EQ++
Sbjct: 721 KMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 780
Query: 683 -------KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
KI EQEEK+R+QEE M+ QEEKM QEEKM QEEKM QEEKM QEEKMW
Sbjct: 781 EKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWG 840
Query: 736 QEVRLRQQEEKMQE 749
QE ++ QEEKM+E
Sbjct: 841 QEEKMWGQEEKMEE 854
Score = 438 bits (1127), Expect = e-123
Identities = 277/666 (41%), Positives = 407/666 (61%), Gaps = 108/666 (16%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E E+ + + L+R+LE + + Q LQ ++ + +++ E + R ++
Sbjct: 238 ESEKSEIQLNVKELKRKLERAKFLLPQV--QTNTLQEEMWRQEEELREQEKKIRKQEEKM 295
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
W+ L + + Q++K R + L ++ L E + +EL+E+ ++Q
Sbjct: 296 ---WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR-EQEKELREQKELREQEEQMQ 351
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERA-----KLLLPQQQLQAEADHLGKELQSVSAKLQ 282
E+ + + ++ +++ +++ R+ ER ++ +Q+++ + + + ++ + + K +
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Query: 283 AQVEENELWNRLN--------QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
E+ ++W ++ Q+QE+K QEEK+QE EE+I+E+E+K+RE+EE +REQE
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEETMREQE 470
Query: 335 EKMRRQEEMMWEKEEK-------------------MRRQEEMMWEKEEKMRRQEEM---- 371
EKM++QEE MWE+EEK M+ QEE +WE+EEK+R QEEM
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 372 --MWEKEEKMRRQEEMMWEKEEKIR-------------------------ELEEKMHEQE 404
MW ++EKMR QE+ MWE+EEK+R + EEKM E+E
Sbjct: 531 KKMW-RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE 589
Query: 405 KIREQEEK-RQEEEKIREQ--------EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
++RE+E+K R+EEE +REQ EK QEQE KMW QEEK++EQEEK+ EQE+KMW
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE 649
Query: 456 QEEKIHEQ-------EKIREEEKRQEQEEMWRQEEKIHEQEEI-----------W----- 492
QEEK+ EQ EK+ E EK QEQE+M QEEKI EQE++ W
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKM 709
Query: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWREEE 551
R++E M E+E+K+R++EE + QEEK++EQEEK++EQEE+MW QEEK+ EQEE MW ++
Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769
Query: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611
++EK+WE EK QEQE K+W QEEK+R+QEEK+ QEEK+R QEEK + QEEKMW QE
Sbjct: 770 LPEQKEKLWEHEKMQEQE-KIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
EK+ QEEK+ QEEK+ QEEK+ EE Q QEEKM EQEEKM QEEKM+EQEE M
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKM---EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Query: 672 RQEEKI 677
QEEKI
Sbjct: 886 GQEEKI 891
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 497 bits (1279), Expect = e-140
Identities = 288/496 (58%), Positives = 357/496 (71%), Gaps = 58/496 (11%)
Query: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
YIE+LTKERDALSLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQ E
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ-------E 303
Query: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
EKIQEQEEK+ EQE KIREQEEKM RQEE M E+EEK+R QE+ MW +EEK+R
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR------- 356
Query: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433
E+EEK+R QEE MW +EEKIRE +EK+ EQE EE ++EEKIREQE+++++ KMW
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEEKRQE--KMW 409
Query: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI---REEEKRQEQEEMWRQEEKIHEQEE 490
RQE+K+REQ+EKIREQE++MWRQEEKI E E++ +EE+ R+ +E+M +EEK+ EQE
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE- 468
Query: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWRE 549
EK+ QEEKI++QEEK WRQ EK+ +QEEKI EQEEKMWRQEEK+ EQEE M +
Sbjct: 469 -----EKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
EEKM QE EK +EQE ++W+QEEK++EQE ++ QE EE++ K
Sbjct: 523 EEKMQRQE-----EKMREQEVRLWQQEEKMQEQEVRL--------------QELEERLGK 563
Query: 610 QEEKI-------REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662
+K RE + I + E K +E + + Q+Q+ G ++ + ++
Sbjct: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Query: 663 MQEQEETMWRQEEKIR 678
+E K+R
Sbjct: 624 ASGKEALPSCSSRKLR 639
Score = 378 bits (971), Expect = e-105
Identities = 234/573 (40%), Positives = 344/573 (60%), Gaps = 89/573 (15%)
Query: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288
K ++ E S++ ++ +L+ QQ H +S++ + Q+ E
Sbjct: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
Query: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 331
E + +++ K W +++ ++E E+ Q +E R +E I
Sbjct: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQ-----------EEMMWEKEEKMRRQEEMMWEKEEKMR 380
E + ++++E M EK R++ E ++ E +E + ++ +M
Sbjct: 130 EVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMG 189
Query: 381 RQEEMMWEKEEKI-----------RELEEKMHE-QEKIREQEEKRQEEEKIREQEKRQEQ 428
E + ++ + + EL+EK E QEK+R E ++ E + + KR+ +
Sbjct: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE 249
Query: 429 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488
A++ +++++ + +++ ++ + + + + E+ ++ +Q++E+MWRQEEKI EQ
Sbjct: 250 RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE--- 545
EE KM EQE KIR+QEEK+WRQEEK+ EQEEKIREQE+KMWRQEEKIREQEE
Sbjct: 310 EE------KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363
Query: 546 -----MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK----VWRQEEKIREQ 596
MWR+EEK+ EQ+ EK QEQE++MWRQEEKIREQEEK +WRQE+K+REQ
Sbjct: 364 EQEEKMWRQEEKIREQD-----EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418
Query: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656
+EK +EQEE+MW+QEEKIRE EE +Q+QEEK+RE EEK+ QE+EEKM EQEEK+
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM-------QEEEEKMQEQEEKI 471
Query: 657 CEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 716
QEEK+QEQEE WRQE K+ +QEEKI EQEE M QEEKMWEQEEKM EQE
Sbjct: 472 QRQEEKIQEQEEKTWRQE--------KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523
Query: 717 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
EKMQ QEEKMR QE ++W+QE ++++QE ++QE
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 365 bits (936), Expect = e-100
Identities = 223/516 (43%), Positives = 325/516 (62%), Gaps = 32/516 (6%)
Query: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271
+++ E +N K + + E + E + K+ K L+R LP + +A H+
Sbjct: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
K V + + + E+ N N +++ ++ ++ E Q++ E +E
Sbjct: 126 KNSDEVKSSFKKRQEK---MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHF 182
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
+ +M E + ++ + + + +E+++ + E +EK+R E E +
Sbjct: 183 DHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
Query: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
+++L+ K+ + + Q++ + E +++ ++ Q AK+ Q E+ ++QE+
Sbjct: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKE--LQSVSAKLQAQVEENELWNLLNQQQEE 297
Query: 452 KMWRQEEKIHEQE-KIREEEK--RQEQEEMWRQEEKIHEQEE--------IWRQKEKMHE 500
KMWRQEEKI EQE K+ E+E R+++E+MWRQEEK+HEQEE +WRQ+EK+ E
Sbjct: 298 KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357
Query: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-----MWREEEKMHE 555
QEEKIR+QEEK+WRQEEKIREQ+EKI+EQEE+MWRQEEKIREQEE MWR+E+KM E
Sbjct: 358 QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Q +EK +EQE++MWRQEEKIRE EE + QEEK+RE EEK QE+EEKM +QEEKI+
Sbjct: 418 Q-----DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
QEEKIQEQEEK Q EK+ +QEE EQEEKM QEEKM EQEEKMQEQEE M RQEE
Sbjct: 473 RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Query: 676 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
K+REQE ++ +QEEK++EQE +QE EE++ + +K
Sbjct: 532 KMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 183 bits (465), Expect = 4e-46
Identities = 125/398 (31%), Positives = 208/398 (52%), Gaps = 81/398 (20%)
Query: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
+ ++AL EL T L + ELQ L + +++ +DL +L
Sbjct: 197 KERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL-------- 248
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRN---TITDEELKEKNAKLQEKLQL 232
E Q L + +ADR +EL L ++ N + +++ +EK + +EK+Q
Sbjct: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE 308
Query: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQ--LQAEADHLGKELQSV------------- 277
E + E +L ++E + K+ R + + +Q+ ++ + D + ++ + +
Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368
Query: 278 -----------SAKLQAQVEE----------------NELWNRLN---------QQQEEK 301
K+Q Q EE ++W + ++QEE+
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428
Query: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
MWRQEEKI+E EE +Q+QEEK+RE EEK++E+EEKM+ QEE + +EEK++ QEE W +
Sbjct: 429 MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW-R 487
Query: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 421
+EK+ +QEE +WE+EEKM RQEE MWE+EEK++E EEKM QE
Sbjct: 488 QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE----------------- 530
Query: 422 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
EK +EQE ++W+QEEK++EQE +++E E+++ + +K
Sbjct: 531 -EKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 494 bits (1272), Expect = e-139
Identities = 287/496 (57%), Positives = 356/496 (71%), Gaps = 58/496 (11%)
Query: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQ E
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ-------E 303
Query: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
EKIQEQEEK+ EQE KIREQEEKM RQEE M E+EEK+R QE+ MW +EEK+R
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR------- 356
Query: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433
E+EEK+R QEE MW +EEKIRE +EK+ EQE EE ++EEKIREQE+++++ KMW
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEEKRQE--KMW 409
Query: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI---REEEKRQEQEEMWRQEEKIHEQEE 490
RQE+K+REQ+EKIREQE++MWRQEEKI E E++ +EE+ R+ +E+M +EEK+ EQE
Sbjct: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE- 468
Query: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWRE 549
EK+ QEEKI++QEEK WRQ EK+ +QEEKI EQEEKMWRQEEK+ EQEE M +
Sbjct: 469 -----EKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
EEKM QE EK +EQE ++W+QEEK++EQE ++ QE EE++ K
Sbjct: 523 EEKMQRQE-----EKMREQEVRLWQQEEKMQEQEVRL--------------QELEERLGK 563
Query: 610 QEEKI-------REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662
+K RE + I + E K +E + + Q+Q+ G ++ + ++
Sbjct: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Query: 663 MQEQEETMWRQEEKIR 678
+E K+R
Sbjct: 624 ASGKEALPSCSSRKLR 639
Score = 377 bits (969), Expect = e-104
Identities = 237/573 (41%), Positives = 337/573 (58%), Gaps = 89/573 (15%)
Query: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288
K ++ E S++ ++ +L+ QQ H +S++ + Q+ E
Sbjct: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
Query: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 331
E + +++ K W +++ ++E E+ Q +E R +E I
Sbjct: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQ-----------EEMMWEKEEKMRRQEEMMWEKEEKMR 380
E + ++++E M EK R++ E ++ E +E + ++ +M
Sbjct: 130 EVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMG 189
Query: 381 RQ-EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ------EAKMW 433
E++ E++ EL E+++E+ + QE+ ++ E EK + Q + K+
Sbjct: 190 TYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE 249
Query: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE-----KRQEQEEMWRQEEKIHEQ 488
R + + +Q+ ++ Q Q ++ E E +Q++E+MWRQEEKI EQ
Sbjct: 250 RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE--- 545
EE KM EQE KIR+QEEK+WRQEEK+ EQEEKIREQE+KMWRQEEKIREQEE
Sbjct: 310 EE------KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363
Query: 546 -----MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK----VWRQEEKIREQ 596
MWR+EEK+ EQ+ EK QEQE++MWRQEEKIREQEEK +WRQE+K+REQ
Sbjct: 364 EQEEKMWRQEEKIREQD-----EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418
Query: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656
+EK +EQEE+MW+QEEKIRE EE +Q+QEEK+RE EEK+ QE+EEKM EQEEK+
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM-------QEEEEKMQEQEEKI 471
Query: 657 CEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 716
QEEK+QEQEE WRQE K+ +QEEKI EQEE M QEEKMWEQEEKM EQE
Sbjct: 472 QRQEEKIQEQEEKTWRQE--------KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523
Query: 717 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
EKMQ QEEKMR QE ++W+QE ++++QE ++QE
Sbjct: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 363 bits (932), Expect = e-100
Identities = 223/516 (43%), Positives = 324/516 (62%), Gaps = 32/516 (6%)
Query: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271
+++ E +N K + + E + E + K+ K L+R LP + +A H+
Sbjct: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
K V + + + E+ N N +++ ++ ++ E Q++ E +E
Sbjct: 126 KNSDEVKSSFKKRQEK---MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHF 182
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
+ +M E + ++ + + +E+++ + E +EK+R E E +
Sbjct: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
Query: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
+++L+ K+ + + Q++ + E +++ ++ Q AK+ Q E+ ++QE+
Sbjct: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKE--LQSVSAKLQAQVEENELWNLLNQQQEE 297
Query: 452 KMWRQEEKIHEQE-KIREEEK--RQEQEEMWRQEEKIHEQEE--------IWRQKEKMHE 500
KMWRQEEKI EQE K+ E+E R+++E+MWRQEEK+HEQEE +WRQ+EK+ E
Sbjct: 298 KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357
Query: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-----MWREEEKMHE 555
QEEKIR+QEEK+WRQEEKIREQ+EKI+EQEE+MWRQEEKIREQEE MWR+E+KM E
Sbjct: 358 QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Q +EK +EQE++MWRQEEKIRE EE + QEEK+RE EEK QE+EEKM +QEEKI+
Sbjct: 418 Q-----DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
QEEKIQEQEEK Q EK+ +QEE EQEEKM QEEKM EQEEKMQEQEE M RQEE
Sbjct: 473 RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Query: 676 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
K+REQE ++ +QEEK++EQE +QE EE++ + +K
Sbjct: 532 KMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 336 bits (862), Expect = 4e-92
Identities = 225/598 (37%), Positives = 343/598 (57%), Gaps = 67/598 (11%)
Query: 162 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
D + DS + L++ + + D + + K D + + E++ E
Sbjct: 88 DDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKR---QEKMNE 144
Query: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
KN ++++ + +K ++L +++ E + LL + A +G ++ ++ +
Sbjct: 145 KNYTFRKRVVI---KKPWLRLGEVTAQKRPENS--LLEETLHFDHAVRMGTYIEKLTKER 199
Query: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
A EL+ +E K EK E +EK++ E + E + +++ + K+ R +
Sbjct: 200 DAP--SLELYRNTITDEELK-----EKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQ 252
Query: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM----RRQEEMMWEKEEKIRELE 397
++ +++++ + + + ++ + + + + E+ E ++QEE MW +EEKI+E E
Sbjct: 253 LLL--PQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
EKM EQE KIREQE+ KMWRQEEK+ EQEEKIREQE KMWRQE
Sbjct: 311 EKMCEQEL------------KIREQEE------KMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ--------EEIWRQKEKMHEQEEKIRKQE 509
EKI EQE E+ R+++E+MWRQEEKI EQ EE+WRQ+EK+ EQEEK ++
Sbjct: 353 EKIREQE----EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK---RQ 405
Query: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE-EEKMHEQEKIW--EEEKRQ 566
EK+WRQE+K+REQ+EKIREQEE+MWRQEEKIRE EEM ++ EEK+ E E+ EEEK Q
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 567 EQEDKMWRQEEKIREQEEKVWRQE------EKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
EQE+K+ RQEEKI+EQEEK WRQE EKI EQEEK QEEKMW+QEEK++EQEEK
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680
+Q QEEK+REQE ++ +QEE QEQE ++ E EE++ + +K + +
Sbjct: 526 MQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPT 585
Query: 681 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE----KMRRQEEKMW 734
I + E K +E + + Q+Q+ ++ + ++ +E R+ K W
Sbjct: 586 LTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 383 bits (984), Expect = e-106
Identities = 223/474 (47%), Positives = 344/474 (72%), Gaps = 46/474 (9%)
Query: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
IT+EELKEKNA+LQE+LQLVE+EKSEIQL++KELKRKLE K+ LPQ+
Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQE------------ 51
Query: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
QV E E R +QE ++ QE +++E E +++EQE ++REQE ++REQ
Sbjct: 52 ---------GQVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 99
Query: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
E ++R QE + E+E ++R QE + E+E ++R QE + E+E ++R QE + E+E ++
Sbjct: 100 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 394 RELEEKMHEQE-KIREQE-EKRQEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIREQE 450
RE E ++ EQE ++REQE + R++E ++REQE + EQE +M QEE++ EQEE++++QE
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE 219
Query: 451 KKMWRQEEKIHEQEKIREEEKRQEQEE-MWRQEEKIHEQEEIWR-QKEKMHEQEEKIRKQ 508
++M QEE++ +QE E+ EQEE + +QEE++ +QEE R Q+E+M EQEE++R+Q
Sbjct: 220 EQMGEQEEQMRKQE-----EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQ 274
Query: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ 568
EE++ +Q+E+ EQEE+ EQEE+M QEE++REQEE RE +EE+ +EQ
Sbjct: 275 EEQMLKQKEQ-TEQEEQTGEQEEQMREQEEQMREQEEQMRE-----------QEEQMREQ 322
Query: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
E++M +QEE++ EQ+E++W Q+E++ +QEE+ EQEE+M KQEE++R+QEE++++QEE++
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQM 382
Query: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
R+QEE++R+QEE EQ+E+MGEQ+E+M EQEE+M EQ+E M +QEE + EQ++
Sbjct: 383 RKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 341 bits (874), Expect = 2e-93
Identities = 192/450 (42%), Positives = 331/450 (73%), Gaps = 30/450 (6%)
Query: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ---EEMMWEKEEKMRRQEEMMWEKEE 363
E+++E ++QE+ + + ++ +I+ ++++R+ +++ +E ++R QE + E+E
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQE-EKRQEEEKIRE 421
++R QE + E+E ++R QE + E+E ++RE E ++ EQE ++REQE + R++E ++RE
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 422 QEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE-KIREEEKRQEQEEMW 479
QE + +EQE ++ QE ++REQE ++REQE ++ QE ++ EQE ++RE
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE----------- 175
Query: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539
QE ++ EQE ++ EQE ++ +QE ++ QEE++ EQEE++++QEE+M QEE+
Sbjct: 176 -QEGQVREQEG------QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQ 228
Query: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599
+R+QEE E+E+ ++ +EE+ Q+QE++M +QEE++REQEE++ QEE++ +Q+E
Sbjct: 229 MRKQEEQMGEQEEQVQK----QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE- 283
Query: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659
+ EQEE+ +QEE++REQEE+++EQEE++REQEE++REQEE +QEE+M EQ+E+M EQ
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
Query: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
+E+M +QEE M QEE++++QE+++R+QEE++R+QEE M++QEE+M +QEE+M EQ+E+M
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM 403
Query: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
EQ+E+MR QEE+M EQ+ ++R+QEE M E
Sbjct: 404 GEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
Score = 193 bits (490), Expect = 6e-49
Identities = 142/458 (31%), Positives = 256/458 (55%), Gaps = 39/458 (8%)
Query: 49 PMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPE 108
P ++ E + K AE +E+L +T S K+K+ P G E
Sbjct: 2 PRITNEELKEKNAELQEEL--QLVETEKSEIQLHIKELKRKLETDKIP-LPQEGQVREQE 58
Query: 109 D---EQKASHQHQEALRRELEAQVHT----IRILTCQKTELQMALYYSQHAVKQLEGEAR 161
EQ+ + QE RE E QV +R Q E + + + V++ EG+ R
Sbjct: 59 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 118
Query: 162 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
+ ++ + G++ + V Q+ + R E +E++ E + ++E +
Sbjct: 119 EQEGQVREQ---EGQVREQEGQVREQEGQV-REQEGQVREQEGQVRE-QEGQVREQEGQV 173
Query: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
+ + Q + Q + + E Q+ +E + + ++ ++Q+Q + + +G++ + + +
Sbjct: 174 REQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE 233
Query: 282 QAQVEENELWNRLNQQ---QEEKMWRQEEKIQEWEEKIQEQEEKI------REQEEKIRE 332
+ E+ E + +Q QEE+M +QEE+++E EE+++EQEE++ EQEE+ E
Sbjct: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293
Query: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
QEE+MR QEE M E+EE+MR QEE M E+EE+M +QEE MWE++E+M Q+E MW++EE+
Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
Query: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
+ E EE+M +QE E+ R++EE++R+QE+ +M +QEE++R+QEE++ EQ+++
Sbjct: 354 MGEQEEQMQKQE-----EQVRKQEEQMRKQEE------QMRKQEEQMRKQEEQMGEQKEQ 402
Query: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
M Q+E++ EQ EE+ +++E+M +QEE + EQ+E
Sbjct: 403 MGEQKEQMREQ----EEQMGEQKEQMRKQEEHMGEQKE 436
>gi|239750781 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 307
Score = 323 bits (829), Expect = 3e-88
Identities = 173/260 (66%), Positives = 196/260 (75%), Gaps = 42/260 (16%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
PHLP HPMMS++TRQ+KLAEAK++ TD+ VGT A+DTKKKKIN+GTNPETTTSG
Sbjct: 5 PHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPETTTSG 64
Query: 103 GCHSPED----------EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHA 152
GCHSPED E+KASHQHQEALRRE+EAQ HTIRILTCQKTEL+ ALYYSQ A
Sbjct: 65 GCHSPEDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDA 124
Query: 153 VKQLE--------------------------------GEARDLISRLHDSWKFAGELEQA 180
++ E GE++DL RLH SW FAGEL++A
Sbjct: 125 ARKFEDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRA 184
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAV+T+ KKADRYIEELTKERDALSLELYRNTIT+EELK+KNA+LQEKL+L ESEKSEI
Sbjct: 185 LSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEI 244
Query: 241 QLNVKELKRKLERAKLLLPQ 260
QLNVKELKRKLERAK LLPQ
Sbjct: 245 QLNVKELKRKLERAKFLLPQ 264
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 285 bits (728), Expect = 1e-76
Identities = 212/807 (26%), Positives = 430/807 (53%), Gaps = 130/807 (16%)
Query: 38 HLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPE 97
H H + +E + + +E+ T+ H Q + +K+++ E
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQ----------ERRKQQLKRDQEEE 483
Query: 98 TTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE 157
E+ ++ + ++ LRRE E + ++ LQ L Q ++ E
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 158 GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
L+ R + LEQ ++++ +R + L +E + L R E
Sbjct: 544 ERREQLLKREEEK-----RLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE---QE 595
Query: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
E E+ K +E +L + E+ E +L +E + + R +LL ++Q + L +E Q
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEE-RRQQLLKSEEQEERRQQQLRREQQER 654
Query: 278 -SAKLQAQVEENELWNRLNQQQEEKMWRQE----------EKI----------------- 309
+L+ + EE L RL ++ EE+ QE E+I
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 310 -----------QEWEEKIQEQEEKIREQEEKIR----------EQEEKMRRQEEMMWEKE 348
QE + + QEQEEK R +E +++ +QEE+ RR W+ E
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
Query: 349 EK-------------MRRQEEMMWEKEEKMRRQEEMMWEKEEK-MRRQEEMMWEKEEKIR 394
EK +R Q E EE+ +R++ + E+EEK RR++ EKE +
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834
Query: 395 ELEEKMHEQEKIREQEEK----RQEEEKIREQEKRQEQEAKMWRQEEKIREQ-------- 442
E EE++ +E+ ++ +E+ ++++E+ R QE+R++Q+ + +EE+ R +
Sbjct: 835 EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Query: 443 -EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501
+E++R++++ + +EE++ +E RE+ +RQEQE +R+EE++ ++EE + + E+
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREE--REKRRRQEQERQYREEEQLQQEEE-----QLLREE 947
Query: 502 EEKIRKQE-EKVWRQEEKIREQEEKIR-EQEEKMWRQE--EKIREQEEMWREEEKMHEQE 557
EK R+QE E+ +R+++K++++EE++ E+ EK RQE +K RE+EE+ +EEE++ +E
Sbjct: 948 REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Query: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
+ E++R+++ ++ +R++++++++EE++ R+E +E++R ++ E+ +++EE+++++
Sbjct: 1008 R---EKRRRQEWERQYRKKDELQQEEEQLLREE-----REKRRLQERERQYREEEELQQE 1059
Query: 618 EEKIQEQEEKIREQEE---KIREQEEMTQEQEEKMGEQEEK--------MCEQEEKMQEQ 666
EE++ +E + R ++E + R++EE+ QE+E+ + E+ EK C +EE++Q++
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 667 EETMWRQEEKIR---EQEKKIREQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQ 722
EE + R+E + R E E++ RE+EE +E+E++++E+ EK QE E+ +EE++Q++
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 723 EEKMRRQE-EKMWEQEVRLRQQEEKMQ 748
EE++ R+E EK ++ R ++EE++Q
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQ 1206
Score = 283 bits (725), Expect = 3e-76
Identities = 219/734 (29%), Positives = 407/734 (55%), Gaps = 110/734 (14%)
Query: 107 PEDEQKASHQHQEALRRELEAQVHTIRILT-CQKTELQMALYYSQHAVKQLEGEARDLIS 165
PE+E+K + Q RRE E ++ + Q+ E L + +++ + R
Sbjct: 812 PEEEEKEQRRRQ---RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
Query: 166 RLHDSWKFAGELEQ--------ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
R W++ E E+ A A+ Q +K + ++E +E E R +
Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER 928
Query: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
+ +E+ QE+ QL+ E+ E +R+ ER + ++LQ + + L E
Sbjct: 929 QYREEEQLQQEEEQLLREER--------EKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Query: 278 SAKLQAQV---EENELWNRLNQQQEEKMWRQEE---KIQEWEEKIQEQEEKIREQEEKIR 331
+ + + EE EL QQ+EE++ R+E + QEWE + ++++E +E+E+ +R
Sbjct: 981 RRRQEREKKYREEEEL-----QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
Query: 332 EQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
E+ EK R QE E + +EE+++++EE + +E + RR++E+ E + R++EE+ E+E
Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL----ERQYRKEEELQQEEE 1091
Query: 391 EKIRELEEKMHEQEK---IREQEEKRQEEEKI--REQEKRQEQEA-KMWRQEEKIREQEE 444
+ +RE EK QE+ RE+EE +QEEE++ E+EKR+ QE + +R+EE+++++EE
Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151
Query: 445 KI-REQEKKMWRQE--EKIHEQEKIREEEK---RQEQEEMWRQEEKIH-EQEEIWRQKEK 497
++ RE+ +K RQE + E+E++++EE+ R+EQE+ ++ E+ + E+EE+ RQK K
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Query: 498 MHEQEEKIRKQEEKVW-----------------RQEEKIR-------------------- 520
++E R + W R+ E+ R
Sbjct: 1212 QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLL 1271
Query: 521 -EQEEKIREQEEKMWRQEEK-IREQEEMWREEEK-MHEQEKIWEEEK---RQEQEDKMWR 574
EQ+E+ REQE + W+Q ++ E+E++ REE+K +++ +EEK R+E+E+K R
Sbjct: 1272 GEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRR 1331
Query: 575 QE--EKIREQEEKVW-RQEEKIREQEEKRQEQEEKMWKQEE--KIREQEEKI--QEQEEK 627
QE K RE+E+ + R+E+ +R QE R+ +EE++ QE+ K E+E+++ QE+E K
Sbjct: 1332 QETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Query: 628 IREQEEKIREQE---EMTQEQEEKMGEQEEKMCEQEE--KMQEQEETMWRQEE--KIREQ 680
++E+++R QE ++ Q+++ K E+E+++ QE K +E+E+ + RQE K E+
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEE 1451
Query: 681 EKKIR-EQEEKIREQEEMMQEQEEKMWEQEE---KMCEQEEKMQEQEEKMRRQEEKMWEQ 736
E+++R E+ K RE+E+++QE+EE+ ++E K E+E++++ QE + +E+++ Q
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Query: 737 EVRLRQQEEKMQEH 750
E + EE+ Q H
Sbjct: 1512 EPERKFLEEEQQLH 1525
Score = 273 bits (699), Expect = 3e-73
Identities = 218/760 (28%), Positives = 422/760 (55%), Gaps = 122/760 (16%)
Query: 53 KETRQSKLAE-----AKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSP 107
+E R+ +LAE A+E++ P+ + + A D ++ K+ + +
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEA-DARQSKVYSRPRKQ---------- 726
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E +++ Q ++ RRE +ELQ H +Q E + RD
Sbjct: 727 EGQRRRQEQEEKRRRRE---------------SELQWQEEERAHRQQQEEEQRRDF---- 767
Query: 168 HDSWKFAGELE-----QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+W++ E + Q LSA +++ +R + +ER + + + +EE KE
Sbjct: 768 --TWQWQAEEKSERGRQRLSARPPLREQRERQLR--AEERQ----QREQRFLPEEEEKE- 818
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ-LQAEADHLGKELQSVSAKL 281
Q + Q E EK L +E ++ ERA+ L ++ LQ + + + Q K
Sbjct: 819 ----QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
Query: 282 QAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR---EQEEKIREQE 334
+ Q+EE R +E++ ++++ +QE EE++Q +E + R EQE + RE+E
Sbjct: 875 RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE 934
Query: 335 EKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRQEE-MMWEKEEKMRRQEEMMWEKEEK 392
+ + +E+++ E+ EK RRQE E + K++K++++EE ++ E+ EK RRQE +E+K
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE-----REKK 989
Query: 393 IRELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
RE EE E+E++ RE+ EKR+ +E R+ K+ E + + +E+ +RE+ EK R QE+
Sbjct: 990 YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE---EEQLLREEREKRRLQER 1046
Query: 452 -KMWRQEEKIHEQEKI-----REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
+ +R+EE++ ++E+ RE +RQE E +R+EE++ ++EE + + E+ EK
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE-----QLLREEPEKR 1101
Query: 506 RKQE-EKVWRQEEKIREQEEK-IREQEEKMWRQ--EEKIREQEEMWREEEKMHEQEKIWE 561
R+QE E+ R+EE+++++EE+ +RE+ EK RQ E + RE+EE+ +EEE++ +E
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE---P 1158
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ-EQEEKMWKQEEKIR----- 615
E++R+++ ++ +R+EE+++++EE++ R+E++ R QE +RQ +EE++ +Q+ K R
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 616 -----------EQEEKIQE--------QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656
E+E +++ + E+ R+ E+ + Q+ + +GEQ+E+
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
Query: 657 CEQEEKMQEQEETMWRQEEKI-REQEKKIREQEEKIREQEEMMQEQEE---KMWEQEEKM 712
EQE + +Q + + +EE++ RE++K+ + ++ K +E++++++E+ E + E + K
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338
Query: 713 CEQEEKMQEQEEK-MRRQE--EKMWEQEVRLRQQEEKMQE 749
E+E+ +QE+EE+ +RRQE K E+E+R ++Q K E
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Score = 265 bits (677), Expect = 1e-70
Identities = 209/653 (32%), Positives = 378/653 (57%), Gaps = 112/653 (17%)
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
E E+ L+ Q +K +R + + RD EL+R +E +E+ A+ +E+LQ +
Sbjct: 143 EQERELAEGEEQSEKQERLEQRDRQRRDE---ELWRQRQEWQEREERRAE-EEQLQSCKG 198
Query: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
++E + ++L+R+ +LL E G+E + Q + E +R+
Sbjct: 199 HETEEFPDEEQLRRR----ELL--------ELRRKGRE--------EKQQQRRERQDRVF 238
Query: 296 QQQEEKMWRQEEKI-QEWEEKIQEQE----EKIREQEEKIREQE-EKMRRQEEMMWEKEE 349
Q++EEK WR+ E + ++ EEK+QE+E +++E+EE++R+ E +++RR+ + ++++
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 350 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
++RR++++ ++EE+ R Q+E E++E+ +QEE +E+++R +E+ EQ+ REQ
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEE---RREQQLRREQEERREQQLRREQ 355
Query: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ----EKKMWRQEEKIHEQEK 465
EE+R+E++ REQE +E+ + R+E+++R +++ REQ E+++ R+++ EQ+
Sbjct: 356 EEERREQQLRREQE--EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413
Query: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR----KQEEKVWRQEEKIRE 521
RE++ R+EQ+ QEE+ HEQ+ ++E+ ++E++ R K+EE+ R E++ R+
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Query: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI-- 579
Q+ K R+QEE+ R+E ++ +EE RE+++ EQ+ E+E+R+EQ K +EE++
Sbjct: 474 QQLK-RDQEEE--RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 580 ---------REQEEK----VWRQEEKIREQEEKRQ----EQEEK---MWKQEEKIR---- 615
REQEE+ + R+EEK EQE + Q EQEE+ + K+EE+ R
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Query: 616 --EQEEKIQEQ---EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ---- 666
EQEE+++++ EE R ++E+ REQ +E EE+ +Q K EQEE+ Q+Q
Sbjct: 591 KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650
Query: 667 -----EETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK-----------MWEQEE 710
E+ + R+EE+ R +++ RE EE+ REQE +EQE+ W+ E
Sbjct: 651 QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 710
Query: 711 KMCEQEEKM-------------QEQEEKMRRQE-EKMWEQEVRL-RQQEEKMQ 748
+ ++ K+ QEQEEK RR+E E W++E R RQQ+E+ Q
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Score = 263 bits (673), Expect = 3e-70
Identities = 204/754 (27%), Positives = 412/754 (54%), Gaps = 120/754 (15%)
Query: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEA-RDLISRL 167
+E+K Q + R + E + ++L ++ Q L Q ++LE R+ + RL
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE--ERLEQRLKREEVERL 610
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIE-ELTKERDALSLELYRNTITDEELK--EKNA 224
+ EQ L ++++ + ++ E +ER L + ++ LK E+
Sbjct: 611 EQEER----REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 225 KLQEKLQLV-ESEKSEIQLNVKELKRKLERAKLLLP--QQQLQAEADHLGKELQSVSAKL 281
+L+++L+ E E+ E +L +E ++ ER K +P Q QL++EAD ++ S K
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQE------------WEEKIQEQEEKIREQ--- 326
+ Q E + +++ E W++EE+ W+ + +E+ E+ R++
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW-EKEEKMRRQE-- 383
+REQ E+ R EE ++ + +EE + ++ R++E+ + E+EE+++R+E
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
Query: 384 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQ-EEEKIR-----------EQEKRQEQEAK 431
+ + E+E+ ++E +E+ QE+ R+Q+ + Q EEE+ R +++ R+EQ+
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 432 MWRQEEKIREQEEKIREQEK-KMWRQEEKIHEQEKI-----REEEKRQEQEEMWRQEEKI 485
+EE RE+ EK R QE+ + +R+EE++ ++E+ RE+ +RQE+E +R+++K+
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 486 HEQEEIW----------RQKEKMHEQEEKIRKQEEKVWRQE-EKIREQE--------EKI 526
++EE +++EK + +EE+++++EE++ R+E EK R QE +++
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 527 REQEEKMWRQEE---KIREQEEMWREEEKM-HEQEKIWEEE---KRQEQEDKMWRQEEKI 579
+++EE++ R+E +++E+E +REEE++ E+E++ EE +R+++ ++ +R+EE++
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 580 REQEEKVWRQE-EKIREQEEKRQ--EQEEKMWKQEEKIREQEEK--IQEQEEKIREQEEK 634
+++EE++ R+E EK R QE +RQ E+EE ++E+ +RE+ EK QE E + RE+EE
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
Query: 635 IREQEEMTQEQEEKMGEQE-EKMCEQEEKMQEQEETMWRQEEKIR--EQEKKIREQEEKI 691
+E+E++ +E+ EK QE E+ +EE++Q++EE + R+E++ R E+E++ RE+EE
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Query: 692 REQEEMMQEQEEK------MWEQEEKMCEQEEK--------------------------- 718
R++ + E++ WE E++ ++ K
Sbjct: 1207 RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQD 1266
Query: 719 ----MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
+ EQ+E+ R QE + W+Q R +EE+++
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLE 1300
Score = 261 bits (666), Expect = 2e-69
Identities = 195/634 (30%), Positives = 363/634 (57%), Gaps = 58/634 (9%)
Query: 156 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 215
LE E ++ R HD K + + L + + + ++ + K A L + T
Sbjct: 37 LEREFGAVLRRPHDP-KTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGL 95
Query: 216 DEELKEKNAKLQEKLQLVESEKSEI-QLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
DEE K A+ K L++ + E Q + R+LE P Q+ + + +EL
Sbjct: 96 DEE---KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEE----PGQRRRQKRQEQEREL 148
Query: 275 QSVSAKLQAQVEENE-LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE--KIREQEEKIR 331
A+ + Q E+ E L R Q+++E++WRQ ++ QE EE+ E+E+ + E +
Sbjct: 149 ----AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
EE++RR+E + ++ + +Q++ ++ + +EE W K E + R+EE ++EE
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 392 --KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
+ REL+E+ + K+ QE +R+ +E+ ++Q++ + ++ +QEE+ REQ+E+ REQ
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 450 EKKMWRQEEKIH-----EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
+++ +QEE+ EQE+ RE++ R+EQEE R+++ EQEE R+++ EQ+ +
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 505 IRKQ--EEKVWRQEEKIREQEEKIREQE---EKMWRQEEKIREQEEMWREEEKMHEQEKI 559
+Q E+ R+E+++R +++ REQ+ E+ R+E+++R ++E R E+K HEQE+
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK-HEQERR 443
Query: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR---------QEQEEKMWKQ 610
+ KR+++E + W + E+ E+ E+ R+++ R+QEE+R +E+ E+ ++
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503
Query: 611 EEKIREQEEKIQEQEEKIREQEE----KIREQEEMTQEQEEK----MGEQEEKMCEQEEK 662
E+++R ++E+ +EQ K +E+EE ++R ++++ +EQEE+ + +EEK EQE +
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 663 MQ----EQEE---TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 715
Q EQEE + ++EE+ R+Q K REQEE++ E+ ++ +E + EQEE+ EQ
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLK-REQEERL---EQRLKREEVERLEQEERR-EQ 618
Query: 716 EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
K +E EE+ R+Q K EQE R +QQ + Q+
Sbjct: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Score = 260 bits (665), Expect = 3e-69
Identities = 210/752 (27%), Positives = 410/752 (54%), Gaps = 119/752 (15%)
Query: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
EQ+ + + L E + + HT+ + +L+ Q ++L+ E R+ R
Sbjct: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
Query: 170 SWKFAGE--LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
++ E L+Q + ++++ R E + R L+ + EE +++ + +
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 228 EKL----QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHL---GKELQSVSAK 280
EK + ++ E+ ++ +E +R+ E + + +LQ E + L +E + + +
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 281 LQAQVEENELWNRLNQ-----------QQEEKMWRQEEKIQEWEEKI-QEQEEKIR--EQ 326
+ EE EL Q Q+ E+ +R+EE++Q+ EE++ +E+ EK R E+
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRQEEMMWEKE-EKMRRQE- 383
E + RE+EE + +E+++ E+ EK RRQE E + +EE+++++EE + +E EK RRQE
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166
Query: 384 EMMWEKEEKIRELEEKM--HEQEKIREQEEKR-QEEEKIREQEKRQE------------- 427
E + +EE++++ EE++ EQEK R++ E++ +EEE+++ Q+++Q
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQ 1226
Query: 428 ------------------QEAKMWRQEEK---------------IREQEEKIREQEKKMW 454
+E + +RQ E + EQ+E+ REQE++ W
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286
Query: 455 RQEEK-IHEQEKI-REEEKRQEQEEMWRQEEKI---HEQEEIWRQKE---KMHEQEEKIR 506
+Q ++ E+E++ REE+K ++ + QEEK E+EE R++E K E+E+ ++
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
Query: 507 KQEEKVWRQEE---KIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQEKIW 560
++EE+ R++E K RE+E + +EQ K +E+++R QE + +EE+++ QE+
Sbjct: 1347 EREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406
Query: 561 E-----EEKRQEQEDKMWRQEE--KIREQEEKVWRQEEK---IREQEEKRQEQEEKMWKQ 610
+ + K +E+E ++ RQE K RE+E++V RQE + + E+++ RQE+ K ++
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 611 EEKIREQEE----------KIQEQEEKIREQEE--KIREQEEMTQEQEEKMGEQEEKMCE 658
E+ ++E+EE K E+E+++R QE K REQE +QE E K E+E+++
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 659 Q--EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 716
Q + K ++E+ + RQE R Q+++ ++++ K RE+E++ QE+EE+ ++E+ +++
Sbjct: 1527 QQRQRKFLQEEQQLRRQE---RGQQRR-QDRDRKFREEEQLRQEREEQQLSRQER--DRK 1580
Query: 717 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
+++EQ+ + + QE K E E +LR+QE + Q
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Score = 260 bits (664), Expect = 4e-69
Identities = 216/750 (28%), Positives = 410/750 (54%), Gaps = 132/750 (17%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+EQ + ++ R+ELE Q L ++ +L + ++ + + + R
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 168 HDSWKFAGELEQA--LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
++ E +++ +K+ A R + K R+ E +R + D +L+++ +
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN---EQFRQ-LEDSQLRDRQS- 1263
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Q+ LQ + E+ E +E +R +R + ++QL+ E KE + K Q
Sbjct: 1264 -QQDLQHLLGEQQERDRE-QERRRWQQRDRHFPEEEQLEREEQ---KEAKRRDRKSQ--- 1315
Query: 286 EENELWNRLNQQQEEKMWRQE--EKIQEWEEKIQEQEEK-IREQEEKIREQEEKMRRQEE 342
EE +L L +++EEK RQE K +E E+ +QE+EE+ +R QE + +EE++R QE+
Sbjct: 1316 EEKQL---LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ 1372
Query: 343 --MMWEKEEKMRRQE-EMMWEKEEKM----RRQEEMMWEKEEKMRRQEEMM--WEKEEKI 393
E+E+++RRQE E + KEE+ R++++ +++ K R +E+ + E++ K
Sbjct: 1373 GRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKF 1432
Query: 394 RELEEKMHEQEKIR---EQEEK---------RQEEEKIREQEKRQ-----------EQEA 430
RE E+++ QE+ R E+E++ R+EE+ ++E+E++Q E+E
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 431 KMWRQEE--KIREQEEKIREQEKKMWRQEEKIHEQEKIRE--------------EEKRQE 474
++ RQE K REQE + +E E+K +E+++H Q++ R+ +++RQ+
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE--KIREQEEKIREQE-E 531
++ +R+EE++ ++ E Q+ E++ K R +E+KV RQE+ K E E+++R QE +
Sbjct: 1553 RDRKFREEEQLRQERE--EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610
Query: 532 KMWRQE--EKIREQEEMW--REEEKMHEQEKIWEEEKRQEQEDKMWRQ--EEKIREQEEK 585
+ RQE K RE E++ REE+++H QE+ + K E+E ++ RQ E+++R ++
Sbjct: 1611 QQLRQERDRKFREDEQLLQEREEQQLHRQER---DRKFLEEEPQLRRQEREQQLRHDRDR 1667
Query: 586 VWRQEEKI----REQEEKRQEQEEKMWKQEEKIR--EQEEKIQEQEEKIREQ--EEKIRE 637
+R+EE++ EQ+ +RQE++ K ++E+++R E+E K ++E+++R Q E K RE
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 638 QEEMTQEQEEKMGEQEE---KMCEQEEKMQEQEETMWRQEE---KIREQEKKIREQEE-- 689
+E++ QE E++ ++E K+ E+E+ E+EE R++E K RE+E+ +E+EE
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 690 --------KIREQEEMMQEQEEKM-----------WEQEEKMCEQEEKMQEQE------- 723
K RE+E++ QE+EE+ WE+E+ E++E+ QE
Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRA 1847
Query: 724 -------EKMRRQEEKMWEQEVRLRQQEEK 746
EK RR+E+++W++E + R+QE +
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQERE 1877
Score = 259 bits (663), Expect = 5e-69
Identities = 185/591 (31%), Positives = 358/591 (60%), Gaps = 66/591 (11%)
Query: 195 IEELTKERDALSLELYRNTITDEELKEKNAKLQEK-LQLVESEK-SEIQLNVKELKRKLE 252
+++ +E D E + +E + + K QE+ +L E E+ SE Q +++ R+
Sbjct: 110 LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRR 169
Query: 253 RAKLLLPQQQLQAEADHLGKELQSVSAKL--------QAQVEENELWNRLNQQQEEKMW- 303
+L +Q+ Q + +E Q S K + Q+ EL + +EEK
Sbjct: 170 DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 304 ---RQEEKIQEWEEKI-QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359
RQ+ QE EEK +++E +R++EEK+ QEE+ +RQ E+ E+EE++R+ E
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKL--QEEEPQRQRELQ-EEEEQLRKLE---- 282
Query: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419
+++RR+ + ++++++RR++++ ++EE+ RE +E+ EQ++ REQ+E+R+E++
Sbjct: 283 --RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 420 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 479
REQE+R+EQ+ + REQEE+ REQ+ + QEE+ EQ+ RE++ R+EQ+
Sbjct: 341 REQEERREQQLR--------REQEEERREQQLRR-EQEEERREQQLRREQQLRREQQ--L 389
Query: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539
R+E+++ ++++ R+++ EQ+ ++E+++ R+++ REQEE+ EQ+ + R+E++
Sbjct: 390 RREQQLRREQQLRREQQLRREQQ---LRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 540 I-REQEEM--W---REEEKMHEQEKIWEEEKRQEQEDKMWR----QEEKIREQEEK---- 585
+ REQEE W EE + HEQE+ ++ KR ++E++ R +EE+ REQ+E+
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Query: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK----IREQEEKIREQEEM 641
+ R++E+ REQ KRQE+EE++ ++++R +++ +EQEE+ ++ +EEK EQE
Sbjct: 507 LRREQEERREQRLKRQEEEERL---QQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 642 TQEQEEKMGEQEEKMCEQEEKMQEQ---EETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Q + + E+ +++ ++EE+ ++Q E R E++++ +E + EQEE+ REQ
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER-REQRLKR 622
Query: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
+E EE+ +Q K EQEE+ Q+Q +RR++++ EQ ++ ++EE++++
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQ---LRREQQERREQRLKREEEEERLEQ 670
Score = 257 bits (656), Expect = 3e-68
Identities = 204/699 (29%), Positives = 390/699 (55%), Gaps = 93/699 (13%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+E++ + +E RR+ + + + + E Q+ Q ++ E R R
Sbjct: 908 EEEEELQREEREKRRRQEQERQY--------REEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 168 HDSWKFAGELEQALSAVATQKKKAD------RYIEELTKERDAL---SLELYRNTITDEE 218
+ K + E+ L +K++ R EEL +E + L E R + +
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Query: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK--ELQS 276
++K+ QE+ QL+ E+ + +L +E + + E +L ++QL E + EL+
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYR-EEEELQQEEEQLLGEERETRRRQELER 1078
Query: 277 VSAKLQA-QVEENELWN----RLNQQQEEKMWRQEEKIQEWEEKI-QEQEEKIREQE--E 328
K + Q EE +L + +Q+ E+ R+EE++Q+ EE++ +E+ EK R QE
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 329 KIREQEEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRQE-EMM 386
+ RE+EE + +E+++ E+ EK RRQE E + +EE+++++EE + +E++ RRQE E
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
Query: 387 WEKEEKIRELEEKMHEQEKIREQEEKRQEEE-------------KIREQEKRQEQEAKMW 433
+ +EE+++ + K +++ + + K Q E K RE E+ ++ E
Sbjct: 1199 YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL 1258
Query: 434 RQEEK-------IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
R + + EQ+E+ REQE++ W+Q ++ +E E+ +R+EQ+E R++ K
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE---EQLEREEQKEAKRRDRKSQ 1315
Query: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546
E++++ R+ E+EEK R+QE + K RE+E+ ++E+EE+ R++E+ R+
Sbjct: 1316 EEKQLLRE-----EREEKRRRQE-----TDRKFREEEQLLQEREEQPLRRQERDRK---- 1361
Query: 547 WREEEKMHEQE--KIWEEE---KRQEQEDKMWRQEEKIREQE-EKVWRQ--EEKIREQEE 598
+REEE H+++ K EEE +RQE+E K ++E+++R QE E+ RQ + K RE+E+
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 599 K--RQEQEEKMWKQEEKIR--EQEEKIQEQEEKIR-EQEEKIREQEEMTQEQEEKM---G 650
+ RQE++ K ++E+++R E+E K E+E+++R E+ K RE+E++ QE+EE+
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Query: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM-QEQEEKMWEQE 709
E++ K E+E++++ QE ++ K REQE + +E E K E+E+ + ++Q ++ + QE
Sbjct: 1482 ERDRKFLEEEQQLRRQE-----RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536
Query: 710 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
EQ+ + QE+ ++ R+ ++ + +E +LRQ+ E+ Q
Sbjct: 1537 ----EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Score = 255 bits (652), Expect = 9e-68
Identities = 190/628 (30%), Positives = 365/628 (58%), Gaps = 86/628 (13%)
Query: 176 ELEQALSAVATQKKKADRYIEE----LTKERDALSLELYRNTITDEELKEKNAKLQEKL- 230
E EQ + K+ DR +E L +ER+ E R TD + +E+ LQE+
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREERE----EKRRRQETDRKFREEEQLLQEREE 1350
Query: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQL---QAEADHLGKELQSVSAKLQAQVEE 287
Q + ++ + + +EL+ + + K L +Q+L + E L +E Q + + Q+ +
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Query: 288 NELWNRLNQQQEEKMWRQEE--KIQEWEEKI--QEQEEKIREQEEKIR-EQEEKMRRQEE 342
+ +R +++E+++ RQE K +E E+++ QE+E K E+E+++R E+ K R +E+
Sbjct: 1411 DR--DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Query: 343 MMWEKEEKMRRQEEM---MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 399
++ E+EE+ ++E E+E+++RRQE ++ K R QE E E K E E++
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQEPERKFLEEEQQ 1523
Query: 400 MHEQEKIR-----EQEEKRQE---------EEKIREQEK----RQEQEAKMWRQEEKIRE 441
+H Q++ R EQ+ +RQE + K RE+E+ R+EQ+ ++ K R
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583
Query: 442 QEEKIR--EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI---HEQEEIWRQKE 496
+E+K+R EQE+K E+++ QE +++ RQE++ +R++E++ E++++ RQ+
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEG--QQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
Query: 497 --KMHEQEEKIRKQE-EKVWR--QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
K E+E ++R+QE E+ R ++ K RE+E+ ++E EE+ R++E+ R+ +REEE
Sbjct: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK----FREEE 1697
Query: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE-EKVWRQEEKIR---EQEEKRQEQEEKM 607
++ +RQE+E K ++E+++R QE E+ +R+EE++R EQE+ R+++ +
Sbjct: 1698 ---------QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
Query: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM---GEQEEKMCEQEEKMQ 664
+EE++R + E EQ+ + +E++ K RE+E++ QE+EE+ E + K E+E+ Q
Sbjct: 1749 ILEEEQLRPERE---EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ 1805
Query: 665 EQEETMWRQEEKI-----REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
E+EE R +++ E++ ++ EQE+++R++ + EE+ QE+ E++E
Sbjct: 1806 EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELW 1865
Query: 720 QEQEEKMRRQ-EEKMWEQEVRLRQQEEK 746
QE+E+K R++ E K+ E+ +R +Q+EE+
Sbjct: 1866 QEEEQKRRQERERKLREEHIRRQQKEEQ 1893
Score = 253 bits (645), Expect = 6e-67
Identities = 191/688 (27%), Positives = 385/688 (55%), Gaps = 102/688 (14%)
Query: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
+ ++ LRRE E + H QK E + + +K+ + E RD + R ++ +
Sbjct: 420 RREQQLRREQEEERHE------QKHEQERR----EQRLKREQEERRDWLKREEETERHEQ 469
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
E +K++ R EE +ER L LE +EE +E+ + +++L+ +
Sbjct: 470 E---------RRKQQLKRDQEEERRER-WLKLE-------EEERREQQERREQQLRREQE 512
Query: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
E+ E +L +E + +L++ L +QQL+ E + ++L + + + E E RL
Sbjct: 513 ERREQRLKRQEEEERLQQR--LRSEQQLRREQEERREQLLKREEEKRLEQERRE--QRLK 568
Query: 296 QQQEEK----MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
++QEE+ + R+EE+ Q+ ++ QE+ + R + E++ E++ RR++ + E+ E+
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 352 RRQEEMMWEKEEKMRRQE---EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
RRQ+ + E++E+ R+Q+ E +E++++R+EE EE++ + ++ HE+E+ RE
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE-----EERLEQRLKREHEEER-RE 682
Query: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
QE +E+E+ RE+ K + + + W+ E + ++ K+ + +K Q + ++EK R
Sbjct: 683 QELAEEEQEQARERIKSRIPKWQ-WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR- 740
Query: 469 EEKRQEQEEMWRQEEKIHEQEE----------IWRQKEKMHEQEEK------IRKQEEKV 512
R+E E W++EE+ H Q++ W+ +EK ++ +R+Q E+
Sbjct: 741 ---RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ 797
Query: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM--WREEEKMHEQEKIWEEEKRQEQED 570
R EE+ + ++ + E+EEK R+ ++ ++E+ EEE++ +E+ ++ QE+ED
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER---AQQLQEEED 854
Query: 571 KMWRQEEKIREQEEKVWRQEEKIR---EQEEKRQEQ--------EEKMWKQEEKIREQEE 619
+ +E+ R QE+ R+++K R E+E KR+ +E++ K+++ ++E+EE
Sbjct: 855 GLQEDQERRRSQEQ---RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 620 KIQEQEEKIR---EQEEKIREQEEMTQEQEEKMGEQEEKMCEQE--------EKMQEQEE 668
++Q +E + R EQE + RE+E++ QE+E+ + E+ EK QE +K+Q++EE
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971
Query: 669 TMWRQEEKIR---EQEKKIREQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQEE 724
+ +E + R E+EKK RE+EE +E+E++++E+ EK QE E+ +++++Q++EE
Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031
Query: 725 KMRRQE---EKMWEQEVRLRQQEEKMQE 749
++ R+E ++ E+E + R++EE QE
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQE 1059
Score = 253 bits (645), Expect = 6e-67
Identities = 193/675 (28%), Positives = 382/675 (56%), Gaps = 88/675 (13%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+EQ + ++ R+ELE Q ++ E+Q Q ++ E R + R
Sbjct: 1119 EEEQLLREEREKRRRQELERQYR-------EEEEVQQE--EEQLLREEPEKRRRQELERQ 1169
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ + + E+ L +K++ +R E +E + L + + DE+ + + K Q
Sbjct: 1170 YREEEELQQEEEQLLREEQEKRRQER--ERQYREEEELQRQKRKQRYRDED-QRSDLKWQ 1226
Query: 228 ---EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
EK V K + E R+LE ++L +Q Q + HL E Q + +
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR--DRQSQQDLQHLLGEQQE-----RDR 1279
Query: 285 VEENELWNRLNQQ--QEEKMWRQEEK-IQEWEEKIQEQEEKIREQEEKIREQEE---KMR 338
+E W + ++ +EE++ R+E+K + + K QE+++ +RE+ E+ R ++E K R
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
Query: 339 RQEEMMWEKEEK-MRRQEEMMWEKEEKMRRQEE--MMWEKEEKMRRQEEMMWEKEEKIRE 395
+E+++ E+EE+ +RRQE +EE++R QE+ E+E+++RRQE +E K +
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQE-----RERKFLK 1394
Query: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
E+++ QE REQ+ ++ + K RE+E++ ++ + + K RE+E+++R QE R
Sbjct: 1395 EEQQLRCQE--REQQLRQDRDRKFREEEQQLSRQER----DRKFREEEQQVRRQE----R 1444
Query: 456 QEEKIHEQEKIREEEKRQEQEE----MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
+ + + E++++R+E R+ +EE R+E+++H QE + K E+E+++R+QE
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE----RDRKFLEEEQQLRRQE-- 1498
Query: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQEKIWEEEKRQEQ 568
++ K REQE + +E E K +E+++ Q+ + +EE+++ QE+ ++R++
Sbjct: 1499 ---RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER---GQQRRQD 1552
Query: 569 EDKMWRQEEKIREQ--EEKVWRQEE----KIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
D+ +R+EE++R++ E+++ RQE ++ EQ+ +RQEQE K + E+++R QE
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE---- 1608
Query: 623 EQEEKIREQEEKIREQEEMTQEQEEKM---GEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Q++ +E++ K RE E++ QE+EE+ E++ K E+E +++ QE R+++ +
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE----REQQLRHD 1664
Query: 680 QEKKIREQEEKIREQEEMM---QEQEEKMWEQEEKM--CEQEEKMQEQEEKMRRQE-EKM 733
+++K RE+E+ ++E EE QE++ K E+E+++ E+E K ++E+++RRQE E+
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Query: 734 WEQEVRLRQQEEKMQ 748
+ +E +LRQ+ E+ Q
Sbjct: 1725 FREEEQLRQETEQEQ 1739
Score = 243 bits (621), Expect = 4e-64
Identities = 196/734 (26%), Positives = 400/734 (54%), Gaps = 118/734 (16%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E +++ Q +E R+LE Q +R ++ + Q L Q ++ E E R+
Sbjct: 264 EPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ + + E+ ++++ +R ++L +E++ E +EE +E+ + +
Sbjct: 322 REQQERREQQEERREQ-QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
++L+ + + E QL ++ +L R + L +QQL+ E ++L+ + Q EE
Sbjct: 381 QQLRREQQLRREQQLRREQ---QLRREQQLRREQQLRRE-----QQLRREQQLRREQEEE 432
Query: 288 NELWNRLNQQQEEKMWRQEEKIQEW---EEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
+++E+++ R++E+ ++W EE+ + E++ R+Q+ K R+QEE+ RR+ +
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK-RDQEEE-RRERWLK 490
Query: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK-----------------EEKMRRQEEMMW 387
E+EE+ +QE +E+++RR++E E+ E+++RR++E
Sbjct: 491 LEEEERREQQER----REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 388 E---KEEKIRELEEKMHEQEKIREQEEKRQE----EEKIREQEKRQEQEAKM---WRQEE 437
E K E+ + LE++ EQ REQEE+R + EE+ R+Q ++EQE ++ ++EE
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 438 KIREQEEKIREQEKKMWRQEE-------KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
R ++E+ REQ K EE K EQE+ R+++ R+EQ+E R+E+++ +EE
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE--RREQRLKREEE 664
Query: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE-------------------QEEKI----R 527
R ++++ + E+ R+++E ++E+ RE ++ K+ R
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 528 EQEEKMWRQEE----KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK----- 578
+QE + RQE+ + RE E W+EEE+ H Q+ +EE+++ W+ EEK
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ---QEEEQRRDFTWQWQAEEKSERGR 781
Query: 579 --------IREQEEKVWRQEEKIREQEEKR---QEQEEKMWKQEEKIREQEEKIQEQEEK 627
+REQ E+ R EE R+Q E+R +E+E++ +++ + RE+E + E+EE+
Sbjct: 782 QRLSARPPLREQRERQLRAEE--RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 628 I--REQEEKIREQEEMTQEQEEKMGEQEEKMCEQ-----EEKMQEQEETMWRQ---EEKI 677
+ RE+ ++++E+E+ QE +E+ QE++ ++ EE+ + + T++ + +E++
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 678 REQEKKIREQEEKIREQE---EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKM 733
R++++ ++E+EE+++ +E QEQE + E+E+ E+E+ ++E+ EK RRQE E+
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 734 WEQEVRLRQQEEKM 747
+ ++ +L+Q+EE++
Sbjct: 960 YRKDKKLQQKEEQL 973
Score = 209 bits (531), Expect = 1e-53
Identities = 161/572 (28%), Positives = 314/572 (54%), Gaps = 75/572 (13%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E E+K + Q+ +E E Q+ R ++ E Q++ ++ E + R R
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR----RQ 1442
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
KF E +Q + ++ + R E+L +ER+ +L+R +E++ K
Sbjct: 1443 ERERKFLEEEQQ----LRQERHRKFREEEQLLQERE--EQQLHR--------QERDRKFL 1488
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
E+ Q + ++ + + +EL+ + K L +QQL + + Q + + Q+
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ------QRQRKFLQEEQQLRR 1542
Query: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKI---QEQEEKIREQEEKIREQEEKMRRQEEMM 344
E + Q ++ K +E+ QE EE+ QE++ K R +E+K+R QE QE
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE-----QERKF 1597
Query: 345 WEKEEKMRRQE---EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 401
E E+++RRQE ++ E++ K R E+++ E+EE+ ++ E++ K E E ++
Sbjct: 1598 MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ----ERDRKFLEEEPQLR 1653
Query: 402 EQEKIREQEEKRQEEEKIREQE----KRQEQEAKMWRQEEKIREQEEKIR--EQEKKMWR 455
QE REQ+ + + K RE+E + +EQ+ + ++ K RE+E+++R E+E+K +
Sbjct: 1654 RQE--REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
Query: 456 QEEKIHEQE---KIREEE---KRQEQEEMWRQE--EKIHEQEEIWRQKEKMHEQEEKIRK 507
+E+++ QE K REEE + EQE++ RQE KI E+E++ ++E E+++R+
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE-----EQQLRR 1766
Query: 508 QE-EKVWRQEEKIRE--QEEKIREQE-EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
QE ++ +R+EE++R+ +E+++R QE ++ +R+EE++R++ E + + + + WEEE
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE 623
+ Q +E QE+++R++ ++ +R EE+ QE+ R+E++E +W++EE+ R QE
Sbjct: 1827 QLQLEE-----QEQRLRQERDRQYRAEEQFATQEKSRREEQE-LWQEEEQKRR-----QE 1875
Query: 624 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
+E K+RE+ + +++EE Q ++ QE K
Sbjct: 1876 RERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 114 bits (284), Expect = 4e-25
Identities = 113/429 (26%), Positives = 211/429 (49%), Gaps = 63/429 (14%)
Query: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
EQ+ Q E E E Q+H + Q+ LQ + Q + RD R +
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQR---QRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
Query: 170 SWKFAGELEQALSAVATQKK--KADRYIEELTKERDALSLE--LYRNTITDEELKEKNAK 225
+ E EQ LS +K ++ + +ER + E L R + +E++ K
Sbjct: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
+E QL++ E+ E QL+ +E RK + L +Q+ + + H +L +
Sbjct: 1621 FREDEQLLQ-EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
Query: 286 EENELWNRLNQQQEEKMWRQEE---KIQEWEEKIQEQEEKIREQE--EKIREQEEKMRRQ 340
EE +L +Q+ ++ +R+EE + QE E K ++E+++R QE K RE+E+ +
Sbjct: 1680 EEQQL----RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQET 1735
Query: 341 EEMMWEKEEKMRR---QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE---KIR 394
E+ ++E+ R+ +E++ E+EE+ R++E ++ K R +E++ E+EE + +
Sbjct: 1736 EQEQLRRQERYRKILEEEQLRPEREEQQLRRQE----RDRKFREEEQLRQEREEQQLRSQ 1791
Query: 395 ELEEKMHEQEKIREQEEKRQ---------------------EEEKIREQEKRQEQEAKMW 433
E + K E+E++R++ E++Q +E+++R++ RQ +
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ------Y 1845
Query: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQE---KIREEEKRQEQEEMWRQEEKIHEQEE 490
R EE+ Q EK R +E+++W++EE+ QE K+REE R++Q+E E++ + E
Sbjct: 1846 RAEEQFATQ-EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE----EQRHRQVGE 1900
Query: 491 IWRQKEKMH 499
I Q+ K H
Sbjct: 1901 IKSQEGKGH 1909
Score = 111 bits (277), Expect = 3e-24
Identities = 101/385 (26%), Positives = 199/385 (51%), Gaps = 40/385 (10%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+EQ + ++ L R+ + + ++ E + + +++ EG+ + R
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ---LRQ 1615
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLE--LYRNTITDEELKEKNAK 225
KF E EQ L +++ ++ + ++R L E L R + +++ K
Sbjct: 1616 ERDRKFR-EDEQLL------QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
+E+ QL++ E E QL +E RK + L +Q+ E L +E Q +L+ +
Sbjct: 1669 FREEEQLLQ-EGEEQQLRRQERDRKFREEEQQLRRQE--RERKFLQEEQQLRRQELERKF 1725
Query: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
E E +L Q+ E++ R++E+ ++ E+ Q + E+ EQ+ + +E++ K R +E++
Sbjct: 1726 REEE---QLRQETEQEQLRRQERYRKILEEEQLRPER-EEQQLRRQERDRKFREEEQLRQ 1781
Query: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM----MWEKEEKIRELEEKMH 401
E+EE+ R +E + K R +E++ E+EE+ R ++ WE+E+ +LEE+
Sbjct: 1782 EREEQQLRSQE----SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL--QLEEQ-- 1833
Query: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 461
EQ +E++ + + EE+ QEK + +E ++W++EE+ R Q E+E+K+ +EE I
Sbjct: 1834 EQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ-----ERERKL--REEHIR 1886
Query: 462 EQEKIREEEKRQEQEEMWRQEEKIH 486
Q+K EE++ ++ E+ QE K H
Sbjct: 1887 RQQK--EEQRHRQVGEIKSQEGKGH 1909
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 251 bits (640), Expect = 2e-66
Identities = 170/512 (33%), Positives = 288/512 (56%), Gaps = 69/512 (13%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P G A +KKKI NG++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSP--GIPAGANRKKKI-NGSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + E A T+ L Q EL +AL S + QL
Sbjct: 62 GYHSPGDS-------ATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQL------ 108
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
E S V T K++ I + K L L++ LK +
Sbjct: 109 --------------TENINSLVRTSKEEKKHEIHLVQK----LGRSLFK-------LKNQ 143
Query: 223 NAK-LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
A+ L + S+ ++Q L+++LE +G++L
Sbjct: 144 TAEPLAPEPPAGPSKVEQLQDETNHLRKELE----------------SVGRQL------- 180
Query: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
QA+VE N++ + LN++QEE++ QEE+++E EE+++EQEE++ EQEE++REQEE++R QE
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQE 240
Query: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 401
E + E+EE++R EE + E+EE++ QEE + E+EE++ QEE + E+EE++RE EE++
Sbjct: 241 ERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLC 300
Query: 402 EQ-EKIREQEEKR-QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
EQ E++REQEE+ ++EE++REQE+R ++ K+ Q E++ E+ EK+ EQE++ QE
Sbjct: 301 EQEERLREQEERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEKLLEQERRQEEQERL 359
Query: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
+ + + E E+ EQE + +Q+E++ +QE + ++ E++ E E + E ++ Q +
Sbjct: 360 LERERLLEEVEELLEQERLRQQDERLWQQETL-QELERLRELERMLELGWEALYEQRAEP 418
Query: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
R E++ + + + E++++E ++ EE
Sbjct: 419 RSGFEELNNENKSTLQLEQQVKELKKSGGAEE 450
Score = 212 bits (540), Expect = 9e-55
Identities = 144/426 (33%), Positives = 246/426 (57%), Gaps = 71/426 (16%)
Query: 195 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--- 251
+E+L + L++ L ++ +L E L + E +K EI L V++L R L
Sbjct: 84 LEDLESQYQELAVALDSSSAIISQLTENINSLVRTSK--EEKKHEIHL-VQKLGRSLFKL 140
Query: 252 --ERAKLLLPQ--------QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 301
+ A+ L P+ +QLQ E +HL KEL+SV +LQA+VE N++ + LN++QEE+
Sbjct: 141 KNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEER 200
Query: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
+ REQEE++REQEE++R QEE + E+EE++R QEE + E+
Sbjct: 201 L---------------------REQEERLREQEERLREQEERLCEQEERLREQEERLREQ 239
Query: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 421
EE++ QEE + E EE++ QEE + E+EE++RE EE++HEQ EE++ E
Sbjct: 240 EERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQ------------EERLCE 287
Query: 422 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE-KIREEEKRQEQEEMWR 480
QE+R + QEE++ EQEE++REQE+++ QEE++ EQE ++ E+EK QE +
Sbjct: 288 QEERLRE------QEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLE 341
Query: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
+ EK+ EQE ++E++ E+E + + EE + ++E++R+Q+E++W Q+E +
Sbjct: 342 EVEKLLEQERRQEEQERLLERERLLEEVEELL---------EQERLRQQDERLW-QQETL 391
Query: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
+E E + RE E+M E WE Q E + +E + + + + E++++E ++
Sbjct: 392 QELERL-RELERMLELG--WEALYEQRAEPRSGFEE--LNNENKSTLQLEQQVKELKKSG 446
Query: 601 QEQEEK 606
+E +
Sbjct: 447 GAEEPR 452
Score = 206 bits (523), Expect = 8e-53
Identities = 121/299 (40%), Positives = 197/299 (65%), Gaps = 19/299 (6%)
Query: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
+EEK HE +++ + + + E E + E++ ++ +RK+ E V RQ
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ-EQEDKMWR 574
+ E + + RQEE++REQEE RE+E E++ E+E+R EQE+++
Sbjct: 180 LQAEVENNQMLSLLNR---RQEERLREQEERLREQE-----ERLREQEERLCEQEERLRE 231
Query: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
QEE++REQEE++ QEE++RE EE+ EQEE++ +QEE++REQEE++ EQEE++ EQEE+
Sbjct: 232 QEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEER 291
Query: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694
+REQEE EQEE++ EQEE++CEQEE+++EQEE + Q EK+ QE ++ E+ EK+ EQ
Sbjct: 292 LREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EKLPGQE-RLLEEVEKLLEQ 349
Query: 695 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV-----RLRQQEEKMQ 748
E +EQE + + E++ E+ E++ EQ E++R+Q+E++W+QE RLR+ E ++
Sbjct: 350 ERRQEEQERLL--ERERLLEEVEELLEQ-ERLRQQDERLWQQETLQELERLRELERMLE 405
Score = 195 bits (495), Expect = 1e-49
Identities = 118/353 (33%), Positives = 223/353 (63%), Gaps = 26/353 (7%)
Query: 393 IRELEEKMHEQEKIREQEEKRQEE--EKI-REQEKRQEQEAKMWRQEEKIREQE-EKIRE 448
I +L E ++ + ++E+K + +K+ R K + Q A+ E + E++++
Sbjct: 105 ISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQD 164
Query: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
+ + ++ E + Q + E + RQEE++ EQEE ++ EQEE++R+Q
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEE------RLREQEERLREQ 218
Query: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWREEEKMHEQEKIWEEEKRQE 567
EE++ QEE++REQEE++REQEE++ QEE++RE EE + +EE++ EQE E+ +E
Sbjct: 219 EERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQE-----ERLRE 273
Query: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
QE+++ QEE++ EQEE++ QEE++ EQEE+ +EQEE++ +QEE++REQEE++ EQ EK
Sbjct: 274 QEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EK 332
Query: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687
+ QE + E E++ ++E+ E++E++ E+E ++E EE + ++E++R+Q++++ +Q
Sbjct: 333 LPGQERLLEEVEKLL--EQERRQEEQERLLERERLLEEVEELL--EQERLRQQDERLWQQ 388
Query: 688 E-----EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
E E++RE E M++ E ++EQ + E++ + + + E+++ E
Sbjct: 389 ETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 441
Score = 191 bits (486), Expect = 2e-48
Identities = 114/329 (34%), Positives = 207/329 (62%), Gaps = 29/329 (8%)
Query: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK-RQEEEKI 419
K E+++ + + ++ E + RQ + E + + L + ++E++REQEE+ R++EE++
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR--QEERLREQEERLREQEERL 215
Query: 420 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI--HEQEKIREEEKRQEQEE 477
REQE+R + QEE++REQEE++REQE+++ QEE++ HE+ +EE+ EQEE
Sbjct: 216 REQEER------LCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEE 269
Query: 478 MWR-QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ 536
R QEE++HEQEE ++ EQEE++R+QEE++ QEE++REQEE++ EQEE++ Q
Sbjct: 270 RLREQEERLHEQEE------RLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQ 323
Query: 537 EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ 596
EE++ EQE++ +E + E EK+ E+E+RQE+++++ +E + E EE + EQ
Sbjct: 324 EERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEE--------LLEQ 375
Query: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 656
E RQ Q+E++W+QE ++ E+++E E + E + EQ + E++ + +
Sbjct: 376 ERLRQ-QDERLWQQE--TLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKST 432
Query: 657 CEQEEKMQEQEETMWRQEEKIREQEKKIR 685
+ E++++E +++ +E + E R
Sbjct: 433 LQLEQQVKELKKSGGAEEPRGSESAAAAR 461
Score = 167 bits (422), Expect = 4e-41
Identities = 82/173 (47%), Positives = 129/173 (74%), Gaps = 3/173 (1%)
Query: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
E+++++ + ++ E + Q + E + + R QEE+++EQEE++REQEE++R
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN---RRQEERLREQEERLREQEERLR 216
Query: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
EQEE EQEE++ EQEE++ EQEE++ EQEE + EE++ EQE+++ EQEE++REQEE
Sbjct: 217 EQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEE 276
Query: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
+ EQEE++ EQEE++ EQEE++ EQEE++R QEE++ EQE RLR+QEE++ E
Sbjct: 277 RLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCE 329
Score = 157 bits (398), Expect = 3e-38
Identities = 86/206 (41%), Positives = 137/206 (66%), Gaps = 7/206 (3%)
Query: 551 EKMHEQEKIWEEEKRQEQE--DKMWRQEEKIREQEEKVWRQEEKIREQE-EKRQEQEEKM 607
E ++ + +EEK+ E K+ R K++ Q + E + E+ Q++ +
Sbjct: 110 ENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHL 169
Query: 608 WKQEEKIREQEEKIQEQEEKI----REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 663
K+ E + Q + E + + R QEE++REQEE +EQEE++ EQEE++CEQEE++
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERL 229
Query: 664 QEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
+EQEE + QEE++ EQE+++RE EE++ EQEE + EQEE++ EQEE++ EQEE++ EQE
Sbjct: 230 REQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQE 289
Query: 724 EKMRRQEEKMWEQEVRLRQQEEKMQE 749
E++R QEE++ EQE RLR+QEE++ E
Sbjct: 290 ERLREQEERLCEQEERLREQEERLCE 315
Score = 81.3 bits (199), Expect = 3e-15
Identities = 50/141 (35%), Positives = 85/141 (60%), Gaps = 14/141 (9%)
Query: 617 QEEKIQEQE--EKIREQEEKIREQEEMTQEQEEKMGEQE-EKMCEQEEKMQEQEETMWRQ 673
+EEK E +K+ K++ Q E G + E++ ++ ++++ E++ RQ
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 674 EEKIREQEKKI----REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
+ E + + R QEE++REQEE ++EQEE++ EQEE++CEQEE++ R Q
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERL-------REQ 232
Query: 730 EEKMWEQEVRLRQQEEKMQEH 750
EE++ EQE RL +QEE+++EH
Sbjct: 233 EERLREQEERLCEQEERLREH 253
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 235 bits (600), Expect = 1e-61
Identities = 180/697 (25%), Positives = 349/697 (50%), Gaps = 67/697 (9%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+E+K HQ Q ALR +L+ + TI IL +K ELQ AL ++QHA +Q EGE+ DL SRL
Sbjct: 199 EEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQHAARQKEGESEDLASRL 258
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
S + GELE+ALSAV+TQ+KKADRY +ELTKERDAL LELY+NT ++E+LK++ ++L+
Sbjct: 259 QYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNEDLKQEKSELE 318
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ-----------QQLQAEAD-------H 269
EKL+++ +EK+ +QLN++EL++KLE +LLL Q QQLQ + H
Sbjct: 319 EKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQLQQAMEERAQLEAH 378
Query: 270 LGKELQSVSAKLQAQVE----------ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
LG+ ++SV Q Q+E E+ +W + QQ E++ E+ + ++QE
Sbjct: 379 LGQVMESVR---QLQMERDKYAENLKGESAMWRQRMQQMSEQVHTLREEKECSMSRVQEL 435
Query: 320 EEKIREQEEKIREQ------------EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
E + E ++ E E++++ + E + ++ E + Q + + E + R
Sbjct: 436 ETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSR 495
Query: 368 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI--REQEEKRQEEEKIREQE-- 423
E+ ++ R E+ E+ E R++ E M R + R+ +E++ E +
Sbjct: 496 LNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSG 555
Query: 424 ------KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 477
+ E + + ++ RE +K+ E ++K+ +E + + + + ++Q +
Sbjct: 556 FVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSELKETVELKSQEAQSLQQQRDQY 615
Query: 478 MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE 537
+ ++ + +++ +KE +H Q + +++ +QE + + E R++ ++ +
Sbjct: 616 LGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQEAQGKAVAEMARQELQETQERL 675
Query: 538 EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQE 597
E +Q + R + + + R+E+ED EE+ E+ V + I E
Sbjct: 676 EAATQQNQQLRAQLSLMAHPGEGDGLDREEEED-----EEEEEEEAVAVPQPMPSIPEDL 730
Query: 598 EKRQEQ----EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653
E R+ + EE+ +++EQ + R + ++ + G
Sbjct: 731 ESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHLLASAQKEPEAAAPAPGTGG 790
Query: 654 EKMC-EQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE----Q 708
+ +C E +Q E + + ++ +++ ++E+ E++ + + + + + E
Sbjct: 791 DSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELEHRCIQLSGETDTIGEYIALY 850
Query: 709 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
+ + +E+ +E+EE + R + E +V+L + +E
Sbjct: 851 QSQRAVLKERHREKEEYISRLAQDKEEMKVKLLELQE 887
Score = 153 bits (387), Expect = 5e-37
Identities = 182/792 (22%), Positives = 340/792 (42%), Gaps = 137/792 (17%)
Query: 3 MWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKLAE 62
MWPQP LP P MS+ETRQSKLA
Sbjct: 1 MWPQPR------------------------------------LPPRPAMSEETRQSKLAA 24
Query: 63 AKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK---ASHQHQE 119
AK++L ++ + +P V T A KKKKI NG+NPETTTSGGCHSPED K A+ Q +
Sbjct: 25 AKKKLREYQQRNSPGVPTGAK--KKKKIKNGSNPETTTSGGCHSPEDTPKDNAATLQPSD 82
Query: 120 -------------ALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISR 166
+L +Q H + E + + S +++QL + L+
Sbjct: 83 DTVLPGGVPSPGASLTSMAASQNHDADNVPNLMDETK--TFSSTESLRQLSQQLNGLVCE 140
Query: 167 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 226
G ++ A K RY ++L D+ + + IT E+LK++N ++
Sbjct: 141 SATCVNGEGP-----ASSANLKDLESRY-QQLAVALDSSYVTNKQLNITIEKLKQQNQEI 194
Query: 227 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
++L E EK E L+ +QLQ +G L S A+LQ +
Sbjct: 195 TDQL---EEEKKECHQKQGALR------------EQLQVHIQTIG-ILVSEKAELQTALA 238
Query: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 346
+ R + + E + ++Q ++ E E + + Q++K R + + +
Sbjct: 239 HTQHAARQKEGESEDL---ASRLQYSRRRVGELERAL----SAVSTQQKKADRYNKELTK 291
Query: 347 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 406
+ + +R + + E +++++ E EEK+R + + EL++K+ E +
Sbjct: 292 ERDALRLELYKNTQSNEDLKQEKS---ELEEKLRVLVTEKAGMQLNLEELQKKLEMTELL 348
Query: 407 REQEEKRQEEEKIREQ-----EKRQEQEAKMWRQEEKIRE---QEEKIREQ---EKKMWR 455
+Q R E +Q E+R + EA + + E +R+ + +K E E MWR
Sbjct: 349 LQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWR 408
Query: 456 QE-EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ-------------KEKMHEQ 501
Q +++ EQ EEK + E + E + ++++ +
Sbjct: 409 QRMQQMSEQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAE 468
Query: 502 EEKIRKQEEKVWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQE 557
E +RK+ E + Q + ++++ E R E QEE++ E E E+W E+ + Q
Sbjct: 469 AEHLRKELEGLAGQLQAQVQDNEGLSRLNRE----QEERLLELERAAELWGEQAEARRQI 524
Query: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
E Q + R + RE +E++ + + + E + ++ RE
Sbjct: 525 L----ETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKREL 580
Query: 618 EEKIQEQEEKIREQEE----KIREQEEMTQEQEEKMGEQE------EKMCEQEEKMQEQE 667
+K+ E +EK+ E +E K +E + + Q++++ +G + +++ ++E + Q
Sbjct: 581 GKKLGELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQL 640
Query: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE--QEEK 725
+ +++++QE + + E R++ + QE+ E +Q +++ Q M + +
Sbjct: 641 LLQTQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDG 700
Query: 726 MRRQEEKMWEQE 737
+ R+EE+ E+E
Sbjct: 701 LDREEEEDEEEE 712
Score = 77.8 bits (190), Expect = 3e-14
Identities = 110/496 (22%), Positives = 221/496 (44%), Gaps = 51/496 (10%)
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
K+L+S +L ++ + + N+ EK+ +Q ++I + +++E++++ +++ +R
Sbjct: 157 KDLESRYQQLAVALDSSYVTNKQLNITIEKLKQQNQEITD---QLEEEKKECHQKQGALR 213
Query: 332 EQ-EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
EQ + ++ ++ EK E +K E++ + RR E+
Sbjct: 214 EQLQVHIQTIGILVSEKAELQTALAHTQHAARQKEGESEDLASRLQYSRRRVGELE---- 269
Query: 391 EKIRELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
R L +Q+K R +E +E + +R + + Q + +QE+ E EEK+R
Sbjct: 270 ---RALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNEDLKQEKS--ELEEKLRVL 324
Query: 450 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQE 509
EK Q + E +K+ E E+ Q+ + + + + +++++
Sbjct: 325 VT------EKAGMQLNLEELQKKLEMTELLLQQ---------FSSRCEAPDANQQLQQAM 369
Query: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE-EKMHEQEKIWEEEKR--- 565
E+ + E + + E +R+ + + + E ++ + MWR+ ++M EQ EEK
Sbjct: 370 EERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTLREEKECSM 429
Query: 566 ---QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ-EEKI 621
QE E + ++ E E E++ Q + E + K+ E + Q + ++
Sbjct: 430 SRVQELETSLAELRNQMAEPPPP--EPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQV 487
Query: 622 QEQE---EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Q+ E REQEE++ E E E GEQ E + E MQ T+ R + R
Sbjct: 488 QDNEGLSRLNREQEERLLELERAA----ELWGEQAEARRQILETMQNDRTTISRALSQNR 543
Query: 679 EQEKKIRE-QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE--KMWE 735
E ++++ E Q ++ E M+ EQ K E +K+ E +EK+ +E ++
Sbjct: 544 ELKEQLAELQSGFVKLTNENMEITSALQSEQHVKR-ELGKKLGELQEKLSELKETVELKS 602
Query: 736 QEVR-LRQQEEKMQEH 750
QE + L+QQ ++ H
Sbjct: 603 QEAQSLQQQRDQYLGH 618
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 228 bits (582), Expect = 1e-59
Identities = 148/485 (30%), Positives = 275/485 (56%), Gaps = 91/485 (18%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P+LP HPMM +E+RQ+KLA AK++L ++ + +P + A + TKKKK ++ +PETTTSG
Sbjct: 5 PYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGI-PAGAKTKKKKTDS--SPETTTSG 61
Query: 103 GCHSPEDEQ------------------------------KASHQHQEALRRELEA----- 127
GCHSP D Q + HQ +EA + E
Sbjct: 62 GCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQM 121
Query: 128 -QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVAT 186
++ TI ILT +K +L+ LY+++ A + E E++DL RL S + ELE+AL AV+T
Sbjct: 122 ERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVST 181
Query: 187 QKKKADR-----------YIEELTKERDALSLELYRNTIT--------DE---ELKEKNA 224
Q+++ DR ++++ KER L+ + + T + DE +K + A
Sbjct: 182 QQQEEDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 225 KLQEKL--------QLVESEK------SEIQLNVKELKRKLERAKLLLPQ------QQLQ 264
+ QE++ L E +K E++ ++ ELK ++ L P +QLQ
Sbjct: 242 RWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQ 301
Query: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
EA HL +E++ + KLQ+QVE N+ + L+++Q++++ QEE ++E E + ++E++
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLC 361
Query: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
EQ E++REQ++ ++ Q E + ++E+++R+QEE + ++EE++++QE+ +W+ QEE
Sbjct: 362 EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWD-------QEE 414
Query: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
+W+KEE++++ EE++ + + +K+ E + ++ E+++ + + E++++E +E
Sbjct: 415 RLWKKEERLQKQEERLALSQ--NHKLDKQLAEPQCSFEDLNNEKKSAL-QLEQQVKELQE 471
Query: 445 KIREQ 449
K+ E+
Sbjct: 472 KLDEE 476
Score = 142 bits (357), Expect = 1e-33
Identities = 88/362 (24%), Positives = 200/362 (55%), Gaps = 18/362 (4%)
Query: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
E + +K++ +LEE +I + + +R E I EK + + ++ + R
Sbjct: 93 ESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKA-DLKTTLYHTKRAARHF 151
Query: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIHEQEEIWRQKEKM 498
EE+ ++ ++ ++I E E+ Q+QEE R+ ++ +++ +
Sbjct: 152 EEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALL 211
Query: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQ-EEKMWRQEEKIRE-QEEMWREEEKMHEQ 556
+ ++ + ++V + ++ + + R + +E+MW+ + R +EE R+ ++ E
Sbjct: 212 NAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQEL 271
Query: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
E+ E K Q E V E+++++ + +++ E + E K++
Sbjct: 272 ERSLSELKNQMAEPPSLAPPA--------VTSVVEQLQDEAKHLRQEVEGL---EGKLQS 320
Query: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676
Q E Q +EQ+++++EQEEM +EQE + ++E++CEQ E+++EQ++T+ Q E+
Sbjct: 321 QVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGER 380
Query: 677 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
+R+QE+++R+QEE++R++EE +Q+QE+++W+QEE++ ++EE++Q+QEE++ + ++
Sbjct: 381 LRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDK 440
Query: 737 EV 738
++
Sbjct: 441 QL 442
Score = 140 bits (354), Expect = 3e-33
Identities = 139/581 (23%), Positives = 279/581 (48%), Gaps = 63/581 (10%)
Query: 186 TQKKKADRYIEELTK---------ERDALSLELYRNTITDEELKE-----KNAKLQEKLQ 231
T+KKK D E T + L++ L +++T +L E K K Q + Q
Sbjct: 46 TKKKKTDSSPETTTSGGCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQ 105
Query: 232 LVESEKSEIQLNVKELKR-------KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
L E++K+ +++ +++R LE+A L + A H +E + ++ +LQ
Sbjct: 106 LEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYS 165
Query: 285 VE-----ENELWNRLNQQQEEKMWR--QEEKIQEWEEKIQEQEEKIREQEEKIRE--QEE 335
++ E L QQQEE +E +Q W ++ ++ + ++ E ++
Sbjct: 166 LQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQV 225
Query: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 395
++ R E K E+ R QE M W+ + R +E EK+ + R +E+ E + E
Sbjct: 226 QLERDEYAKHIKGERARWQERM-WKMSVEARTLKE---EKKRDIHRIQEL----ERSLSE 277
Query: 396 LEEKMHEQEKIREQE-----EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
L+ +M E + E+ Q+E K QE + E K+ Q E + +EQ+
Sbjct: 278 LKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEV-EGLEGKLQSQVENNQALSLLSKEQK 336
Query: 451 KKMWRQEEKIHEQE--KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
+++ QEE + EQE ++RE+E+ EQ E R+++K ++ Q E++ +QE+++RKQ
Sbjct: 337 QRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQE-----QGERLRKQEQRLRKQ 391
Query: 509 EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE--MWREEEKMHEQ--EKIWEEEK 564
EE++ ++EE++++QE+++ +QEE++W++EE++++QEE + K+ +Q E E
Sbjct: 392 EERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFED 451
Query: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM-WKQEEKIREQEEKIQE 623
++ + E++++E +EK+ EE + + Q+ E ++ + + +
Sbjct: 452 LNNEKKSALQLEQQVKELQEKL--DEEHLEAASHQNQQLETQLSLVALPGEGDGGQHLDS 509
Query: 624 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK 683
+EE+ I E E + M +EK E+ E+ E + Q + + ++
Sbjct: 510 EEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQ--VERRELGFVQPSGVTDGMRE 567
Query: 684 ---IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
+ E + + E ++ ++EE+M + ++QE
Sbjct: 568 SFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLLELQE 608
Score = 113 bits (282), Expect = 7e-25
Identities = 99/450 (22%), Positives = 219/450 (48%), Gaps = 52/450 (11%)
Query: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
+ + QE ++ I + E I +++ ++ E + EE + E+ + E++
Sbjct: 68 DSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQL---EEAKKTNNEIHKAQMERL 124
Query: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEKIREQEK 424
+ EK + + ++ + R EE+ + +++ ++ QE E+
Sbjct: 125 ETINILTLEKADL----KTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVS 180
Query: 425 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE---EKIHEQEKIREEEKRQEQEEMWRQ 481
Q+QE ++ RE + W Q+ E+ + + + +Q ++ R
Sbjct: 181 TQQQE----------EDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERD 230
Query: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE---- 537
E H + E R +E+M + + R +E+ R +I+E E + E + +M
Sbjct: 231 EYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAP 290
Query: 538 -------EKIREQEEMWREEEKMHEQEKIWEEEKRQ-------EQEDKMWRQEEKIREQE 583
E+++++ + R+E + E + + E Q EQ+ ++ QEE +REQE
Sbjct: 291 PAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQE 350
Query: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK--IQEQEEKIREQEEKIREQEEM 641
+ R++E++ EQ E+ +EQ++ + +Q E++R+QE++ +QEE++R++EE
Sbjct: 351 AQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLR---------KQEERLRKEEER 401
Query: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETM-WRQEEKIREQEKKIREQEEKIREQEEMMQE 700
Q+QE+++ +QEE++ ++EE++Q+QEE + Q K+ +Q + + E + +++ +
Sbjct: 402 LQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQ 461
Query: 701 QEEKMWEQEEKMCEQE-EKMQEQEEKMRRQ 729
E+++ E +EK+ E+ E Q +++ Q
Sbjct: 462 LEQQVKELQEKLDEEHLEAASHQNQQLETQ 491
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 226 bits (576), Expect = 6e-59
Identities = 174/607 (28%), Positives = 320/607 (52%), Gaps = 121/607 (19%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P+LP HPMM +E+RQ+KLA AK++L ++ + +P + A + TKKKK ++ +PETTTSG
Sbjct: 5 PYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGI-PAGAKTKKKKTDS--SPETTTSG 61
Query: 103 GCHSPEDEQ------------------------------KASHQHQEALRRELEA----- 127
G HSP D Q + HQ +EA + E
Sbjct: 62 GGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQM 121
Query: 128 -QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVAT 186
Q+ TI ILT +K +L+ LY+++ A + E E++DL RL S + ELE+ALSAV+T
Sbjct: 122 EQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVST 181
Query: 187 QKKKADRY-----------IEELTKERDALSLELYRNTIT--------DE---ELKEKNA 224
Q+++ DR +++ KER L+ + + T + DE +K + A
Sbjct: 182 QQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 225 KLQEKL--------QLVESEK------SEIQLNVKELKRKLERAKLLLPQ------QQLQ 264
+ QE++ L E +K E++ ++ ELK ++ L P +QLQ
Sbjct: 242 RWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQ 301
Query: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
EA HL +E++ + KLQ+QVE N+ + L+++Q++++ QEE ++E E + ++E++
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLC 361
Query: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
EQ E++REQ++ ++ Q E + ++E+++R+QEE + ++EE++++QE+ +W++EE++ ++EE
Sbjct: 362 EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEE 421
Query: 385 MMWEKEEKI-----RELEEKMHE-----QEKIREQEEKRQEEEKIRE-QEKRQEQEAKMW 433
+ ++EE++ +L++++ E ++ E++ Q E++++E QEK E+ +
Sbjct: 422 RLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAA 481
Query: 434 RQEEKIREQE-------------EKIREQEKKMWRQEEKIHEQEKIRE---------EEK 471
Q + E + + + +E++ R I E + RE +EK
Sbjct: 482 SQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEK 541
Query: 472 RQEQEEMWRQEEKIHEQEEI---WRQKEKMHEQEEKI---RKQE-EKVWRQEEKIREQEE 524
E++ R+E + + R+ ++E + + R QE E V R +K E +
Sbjct: 542 ADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKV 601
Query: 525 KIREQEE 531
K+ E +E
Sbjct: 602 KLLELQE 608
Score = 143 bits (360), Expect = 7e-34
Identities = 87/362 (24%), Positives = 200/362 (55%), Gaps = 18/362 (4%)
Query: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
E + +K++ +LEE +I + + ++ E I EK + + ++ + R
Sbjct: 93 ESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEKA-DLKTTLYHTKRAARHF 151
Query: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIHEQEEIWRQKEKM 498
EE+ ++ ++ ++I E E+ Q+QEE R+ ++ +++ +
Sbjct: 152 EEESKDLAGRLQYSLQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQQTIKERALL 211
Query: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQ-EEKMWRQEEKIRE-QEEMWREEEKMHEQ 556
+ ++ + ++V + ++ + + R + +E+MW+ + R +EE R+ ++ E
Sbjct: 212 NAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQEL 271
Query: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
E+ E K Q E V E+++++ + +++ E + E K++
Sbjct: 272 ERSLSELKNQMAEPPSLAPPA--------VTSVVEQLQDEAKHLRQEVEGL---EGKLQS 320
Query: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676
Q E Q +EQ+++++EQEEM +EQE + ++E++CEQ E+++EQ++T+ Q E+
Sbjct: 321 QVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGER 380
Query: 677 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
+R+QE+++R+QEE++R++EE +Q+QE+++W+QEE++ ++EE++Q+QEE++ + ++
Sbjct: 381 LRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDK 440
Query: 737 EV 738
++
Sbjct: 441 QL 442
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 225 bits (573), Expect = 1e-58
Identities = 173/607 (28%), Positives = 319/607 (52%), Gaps = 121/607 (19%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P+LP HPMM +E+RQ+KLA AK++L ++ + +P + A + TKKKK ++ +PETTTSG
Sbjct: 5 PYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGI-PAGAKTKKKKTDS--SPETTTSG 61
Query: 103 GCHSPEDEQ------------------------------KASHQHQEALRRELEA----- 127
G HSP D Q + HQ +EA + E
Sbjct: 62 GGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQM 121
Query: 128 -QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVAT 186
Q+ TI ILT +K +L+ LY+++ A + E E++DL RL S + ELE+AL AV+T
Sbjct: 122 EQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVST 181
Query: 187 QKKKADRY-----------IEELTKERDALSLELYRNTIT--------DE---ELKEKNA 224
Q+++ DR +++ KER L+ + + T + DE +K + A
Sbjct: 182 QQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 225 KLQEKL--------QLVESEK------SEIQLNVKELKRKLERAKLLLPQ------QQLQ 264
+ QE++ L E +K E++ ++ ELK ++ L P +QLQ
Sbjct: 242 RWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQ 301
Query: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
EA HL +E++ + KLQ+QVE N+ + L+++Q++++ QEE ++E E + ++E++
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLC 361
Query: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
EQ E++REQ++ ++ Q E + ++E+++R+QEE + ++EE++++QE+ +W++EE++ ++EE
Sbjct: 362 EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEE 421
Query: 385 MMWEKEEKI-----RELEEKMHE-----QEKIREQEEKRQEEEKIRE-QEKRQEQEAKMW 433
+ ++EE++ +L++++ E ++ E++ Q E++++E QEK E+ +
Sbjct: 422 RLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAA 481
Query: 434 RQEEKIREQE-------------EKIREQEKKMWRQEEKIHEQEKIRE---------EEK 471
Q + E + + + +E++ R I E + RE +EK
Sbjct: 482 SQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEK 541
Query: 472 RQEQEEMWRQEEKIHEQEEI---WRQKEKMHEQEEKI---RKQE-EKVWRQEEKIREQEE 524
E++ R+E + + R+ ++E + + R QE E V R +K E +
Sbjct: 542 ADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKV 601
Query: 525 KIREQEE 531
K+ E +E
Sbjct: 602 KLLELQE 608
Score = 140 bits (353), Expect = 4e-33
Identities = 87/362 (24%), Positives = 199/362 (54%), Gaps = 18/362 (4%)
Query: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
E + +K++ +LEE +I + + ++ E I EK + + ++ + R
Sbjct: 93 ESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEKA-DLKTTLYHTKRAARHF 151
Query: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIHEQEEIWRQKEKM 498
EE+ ++ ++ + I E E+ Q+QEE R+ ++ +++ +
Sbjct: 152 EEESKDLAGRLQYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRLQQTIKERALL 211
Query: 499 HEQEEKIRKQEEKVWRQEEKIREQEEKIREQ-EEKMWRQEEKIRE-QEEMWREEEKMHEQ 556
+ ++ + ++V + ++ + + R + +E+MW+ + R +EE R+ ++ E
Sbjct: 212 NAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQEL 271
Query: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
E+ E K Q E V E+++++ + +++ E + E K++
Sbjct: 272 ERSLSELKNQMAEPPSLAPPA--------VTSVVEQLQDEAKHLRQEVEGL---EGKLQS 320
Query: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676
Q E Q +EQ+++++EQEEM +EQE + ++E++CEQ E+++EQ++T+ Q E+
Sbjct: 321 QVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGER 380
Query: 677 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
+R+QE+++R+QEE++R++EE +Q+QE+++W+QEE++ ++EE++Q+QEE++ + ++
Sbjct: 381 LRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDK 440
Query: 737 EV 738
++
Sbjct: 441 QL 442
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 224 bits (570), Expect = 3e-58
Identities = 172/607 (28%), Positives = 321/607 (52%), Gaps = 121/607 (19%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P+LP HPMM +E+RQ+KLA AK++L ++ + +P + A + TKKKK ++ +PETTTSG
Sbjct: 5 PYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGI-PAGAKTKKKKTDS--SPETTTSG 61
Query: 103 GCHSPEDEQ------------------------------KASHQHQEALRRELEA----- 127
G HSP D Q + HQ +EA + E
Sbjct: 62 GGHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQM 121
Query: 128 -QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVAT 186
++ TI ILT +K +L+ LY+++ A + E E++DL RL S + ELE+AL AV+T
Sbjct: 122 ERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVST 181
Query: 187 QKKKADRY-----------IEELTKERDALSLELYRNTIT--------DE---ELKEKNA 224
Q+++ DR +++ KER L+ + + T + DE +K + A
Sbjct: 182 QQQEEDRSSSCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 225 KLQEKL--------QLVESEK------SEIQLNVKELKRKLERAKLLLPQ------QQLQ 264
+ QE++ L E +K E++ ++ ELK ++ + L P +QLQ
Sbjct: 242 RWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQ 301
Query: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
EA HL +E++ + KLQ+QVE N+ + L+++Q++++ QEE ++E E + ++E++
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLC 361
Query: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
EQ E++REQ++ ++ Q E + ++E+++R+QEE + ++EE++++QE+ +W++EE++ ++EE
Sbjct: 362 EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEE 421
Query: 385 MMWEKEEKI-----RELEEKMHE-----QEKIREQEEKRQEEEKIRE-QEKRQEQEAKMW 433
+ ++EE++ +L++++ E ++ E++ Q E++++E QEK E+ +
Sbjct: 422 RLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAA 481
Query: 434 RQEEKIREQE-------------EKIREQEKKMWRQEEKIHEQEKIRE---------EEK 471
Q+ + E + + + +E++ R I E + RE +EK
Sbjct: 482 SQQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEK 541
Query: 472 RQEQEEMWRQEEKIHEQEEI---WRQKEKMHEQEEKI---RKQE-EKVWRQEEKIREQEE 524
E++ R+E + + R+ ++E + + R QE E V R +K E +
Sbjct: 542 ADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKV 601
Query: 525 KIREQEE 531
K+ E +E
Sbjct: 602 KLLELQE 608
Score = 143 bits (361), Expect = 5e-34
Identities = 90/368 (24%), Positives = 207/368 (56%), Gaps = 30/368 (8%)
Query: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
E + +K++ +LEE +I + + +R E I EK + + ++ + R
Sbjct: 93 ESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKA-DLKTTLYHTKRAARHF 151
Query: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502
EE+ ++ ++ ++I E E+ Q+QEE ++ R+ +H +
Sbjct: 152 EEESKDLAGRLQYSLQRIQELERALCAVSTQQQEE---------DRSSSCREAV-LHRRL 201
Query: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR--QEEKIREQEEMWREEEKMHEQEKIW 560
++ K+ + ++ E ++++ + ++ + + E+ R QE MW KM + +
Sbjct: 202 QQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMW----KMSVEARTL 257
Query: 561 EEEKRQE--QEDKMWRQEEKIREQEEK--------VWRQEEKIREQEEKRQEQEEKMWKQ 610
+EEK+++ + ++ R +++ Q K V E+++++ + +++ E +
Sbjct: 258 KEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGL--- 314
Query: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670
E K++ Q E Q +EQ+++++EQEEM +EQE + ++E++CEQ E+++EQ++T+
Sbjct: 315 EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTL 374
Query: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Q E++R+QE+++R+QEE++R++EE +Q+QE+++W+QEE++ ++EE++Q+QEE++ +
Sbjct: 375 QEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQ 434
Query: 731 EKMWEQEV 738
++++
Sbjct: 435 NHKLDKQL 442
Score = 112 bits (281), Expect = 1e-24
Identities = 120/522 (22%), Positives = 248/522 (47%), Gaps = 53/522 (10%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
+E + K A ++KL+ + KS I K K+K + + + D +EL
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQEL 74
Query: 275 QSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
+ + NE L QQ+++ E +++E ++ E + E+ E I
Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQV----EHQLEEAKKTNNEIHKAQMERLETINIL 130
Query: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
+ + ++ + R EE + +++ + + E E + E++
Sbjct: 131 TLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSS 190
Query: 394 RELEEKMHE--QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
E +H Q+ I+E+ ++ E K+ + E R E + E+ R QE+
Sbjct: 191 SCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLE----RDEYAKHIKGERARWQER 246
Query: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK-QEE 510
MW+ E ++EE+KR IH +E+ R ++ Q K
Sbjct: 247 -MWKMSV---EARTLKEEKKRD-----------IHRIQELERSLSELKNQMAKPPSLAPP 291
Query: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
V E+++++ + +R++ E + E K++ Q E + + +++K ++ QEQE+
Sbjct: 292 AVTSVVEQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQK----QRLQEQEE 344
Query: 571 KMWRQE-EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629
+ QE +++REQE ++ Q E++REQ++ QEQ E++ KQE+++R
Sbjct: 345 MLREQEVQRVREQE-RLCEQNERLREQQKTLQEQGERLRKQEQRLR-------------- 389
Query: 630 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM-WRQEEKIREQEKKIREQE 688
+QEE++R++EE Q+QE+++ +QEE++ ++EE++Q+QEE + Q K+ +Q + +
Sbjct: 390 KQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSF 449
Query: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQE-EKMQEQEEKMRRQ 729
E + +++ + E+++ E +EK+ E+ E +Q +++ Q
Sbjct: 450 EDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQ 491
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 222 bits (566), Expect = 9e-58
Identities = 115/182 (63%), Positives = 153/182 (84%), Gaps = 6/182 (3%)
Query: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
+E++M +E+K+RE+EE + QEEK++EQEEK +EQEEKMW+QEEK++EQEEK+ EQEEK
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687
+ EQEEK+ EQ+ + EQ+EKM EQ+E++ E+EE+M+EQ+ MW+Q EK+RE++K Q
Sbjct: 63 MWEQEEKMWEQQRLP-EQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKK---TQ 116
Query: 688 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
EEK++EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKM EQE +++ QEEKM
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 748 QE 749
++
Sbjct: 177 RD 178
Score = 217 bits (552), Expect = 4e-56
Identities = 112/198 (56%), Positives = 152/198 (76%), Gaps = 4/198 (2%)
Query: 473 QEQEEMWRQEEKIHEQEEIWR-QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531
+E+E M +E+K+ E+EE+ R Q+EKM EQEEK+R+QEEK+W QEEK++EQEEK+ EQEE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 532 KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591
KMW QEEK+ EQ+ + ++EKM EQ++ E++ + +E KMW+Q EK+RE+++ QEE
Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT---QEE 118
Query: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
K++EQEEK QEQEE MW+QEEK++EQEEK+ EQEEK+REQEEK+REQEE Q QEEKM +
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Query: 652 QEEKMCEQEEKMQEQEET 669
E E E + T
Sbjct: 179 VEPAGGEAGEGSPQDNPT 196
Score = 214 bits (546), Expect = 2e-55
Identities = 118/217 (54%), Positives = 160/217 (73%), Gaps = 9/217 (4%)
Query: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWREEEKMHEQE-KIWE-EE 563
++EE++ +E+K+RE+EE +REQEEKM QEEK+REQEE MW +EEKM EQE K+WE EE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQE 623
K EQE+KMW Q+ ++ EQ+EK+W Q+E++RE+EE+ +EQ KMW+Q EK+RE+++
Sbjct: 62 KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKT--- 115
Query: 624 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK 683
QEEK++EQEEK++EQEEM EQEEKM EQEEKM EQEEKM+EQEE M QEEK++ QE+K
Sbjct: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
Query: 684 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
+R+ E E E + E + C + Q
Sbjct: 176 MRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQ 212
Score = 212 bits (539), Expect = 1e-54
Identities = 114/202 (56%), Positives = 149/202 (73%), Gaps = 14/202 (6%)
Query: 529 QEEKMWRQEEKIREQEEMWRE-EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
+EE+M +E+K+RE+EEM RE EEKM EQE EK +EQE+KMW QEEK++EQEEK+W
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQE-----EKMREQEEKMWEQEEKMQEQEEKMW 57
Query: 588 RQEEKIREQEEKRQEQE------EKMWKQEEKIREQEEKIQEQE--EKIREQEEKIREQE 639
QEEK+ EQEEK EQ+ EKMW+Q+E++RE+EE+++EQ+ +++ + EK + QE
Sbjct: 58 EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117
Query: 640 EMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQ 699
E QEQEEKM EQEE M EQEEKMQEQEE MW QEEK+REQE+K+REQEEK++ QEE M+
Sbjct: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
Query: 700 EQEEKMWEQEEKMCEQEEKMQE 721
+ E E E + QE
Sbjct: 178 DVEPAGGEAGEGSPQDNPTAQE 199
Score = 207 bits (528), Expect = 2e-53
Identities = 112/223 (50%), Positives = 156/223 (69%), Gaps = 13/223 (5%)
Query: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501
+EE++RE+EKKM +EE + EQE EK QEQEE R++E E++W Q+EKM EQ
Sbjct: 3 EEERMREREKKMREEEEMMREQE-----EKMQEQEEKMREQE-----EKMWEQEEKMQEQ 52
Query: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561
EEK+ +QEEK+W QEEK+ EQ+ ++ EQ+EKMW Q+E++RE+EE RE++ + EK+
Sbjct: 53 EEKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM-- 109
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
EK++ QE+KM QEEK++EQEE +W QEEK++EQEEK EQEEKM +QEEK+REQEEK+
Sbjct: 110 REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 169
Query: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Q QEEK+R+ E E E + + E + C + Q
Sbjct: 170 QGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQ 212
Score = 200 bits (509), Expect = 4e-51
Identities = 101/180 (56%), Positives = 137/180 (76%), Gaps = 20/180 (11%)
Query: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
R+EE+++E E+K++E+EE +REQEEK++EQEEKMR QEE MWE+EEKM+ QEE MWE+EE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ-----------------EKI 406
KM QEE MWE ++++ Q+E MWE++E++RE EE+M EQ EK+
Sbjct: 62 KMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
Query: 407 REQEEKRQEEEKI--REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 464
+EQEEK QE+E++ ++EK QEQE KMW QEEK+REQEEK+REQE+KM QEEK+ + E
Sbjct: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
Score = 199 bits (505), Expect = 1e-50
Identities = 105/193 (54%), Positives = 148/193 (76%), Gaps = 14/193 (7%)
Query: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356
++EE+M +E+K++E EE ++EQEEK++EQEEK+REQEEK MWE+EEKM+ QEE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK-------MWEQEEKMQEQEE 54
Query: 357 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 416
MWE+EEKM QEE MWE ++++ Q+E MWE++E++RE EE+M EQ K+ +Q EK +E+
Sbjct: 55 KMWEQEEKMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREK 112
Query: 417 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
+K +E EK QEQE KM QEE + EQEEK++EQE+KMW QEEK+ EQ EE+ R+++E
Sbjct: 113 KKTQE-EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ----EEKMREQEE 167
Query: 477 EMWRQEEKIHEQE 489
+M QEEK+ + E
Sbjct: 168 KMQGQEEKMRDVE 180
Score = 199 bits (505), Expect = 1e-50
Identities = 109/196 (55%), Positives = 147/196 (75%), Gaps = 22/196 (11%)
Query: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 398
R+EE M E+E+KMR +EEMM E+EEKM+ E+EEKMR QEE MWE+EEK++E EE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQ-------EQEEKMREQEEKMWEQEEKMQEQEE 54
Query: 399 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 458
KM EQE E+ ++EEK+ EQ++ EQ+ KMW Q+E++RE+EE++REQ KMW+Q E
Sbjct: 55 KMWEQE-----EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVE 107
Query: 459 KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE-IWRQKEKMHEQEEKIRKQEEKVWRQEE 517
K+ E++K +E E+M QEEK+ EQEE +W Q+EKM EQEEK+ +QEEK+ QEE
Sbjct: 108 KMREKKKTQE-------EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160
Query: 518 KIREQEEKIREQEEKM 533
K+REQEEK++ QEEKM
Sbjct: 161 KMREQEEKMQGQEEKM 176
Score = 198 bits (503), Expect = 2e-50
Identities = 112/212 (52%), Positives = 152/212 (71%), Gaps = 16/212 (7%)
Query: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEKIREQEKR 425
R+EE M E+E+KMR +EEMM E+EEK++E EEKM EQE K+ EQEEK QE+E EK
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-----EKM 56
Query: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
EQE KMW QEEK+ EQ+ ++ EQ++KMW Q+ E++RE+E+R +++MW+Q EK+
Sbjct: 57 WEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQD------ERLREKEERMREQKMWQQVEKM 109
Query: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545
E+++ Q+EKM EQEEK+++QEE +W QEEK++EQEEK+ EQEEKM QEEK+REQEE
Sbjct: 110 REKKK--TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
Query: 546 -MWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
M +EEKM + E E +D QE
Sbjct: 168 KMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
Score = 194 bits (493), Expect = 3e-49
Identities = 113/200 (56%), Positives = 145/200 (72%), Gaps = 21/200 (10%)
Query: 414 QEEEKIREQEKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 472
+EEE++RE+EK+ +E +M R QEEK++EQEEK+REQE+KMW QEEK+ EQE EK
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-----EKM 56
Query: 473 QEQEE-MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE-----KVWRQEEKIREQEEKI 526
EQEE MW QEEK+ EQ+ + QKEKM EQ+E++R++EE K+W+Q EK+R EK
Sbjct: 57 WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKK 113
Query: 527 REQEEKMWRQEEKIREQEE-MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585
+ QEEKM QEEK++EQEE MW +EEKM EQ EEK EQE+KM QEEK+REQEEK
Sbjct: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ-----EEKMWEQEEKMREQEEKMREQEEK 168
Query: 586 VWRQEEKIREQEEKRQEQEE 605
+ QEEK+R+ E E E
Sbjct: 169 MQGQEEKMRDVEPAGGEAGE 188
Score = 194 bits (493), Expect = 3e-49
Identities = 112/204 (54%), Positives = 148/204 (72%), Gaps = 32/204 (15%)
Query: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385
+EE++RE+E+KMR +EEMM E+EEKM+ E+EEKMR QEE MWE+EEKM+ QEE
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQ-------EQEEKMREQEEKMWEQEEKMQEQEEK 55
Query: 386 MWEKEEKIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQEQEAKMWRQEEKIRE--- 441
MWE+EEK+ E EEKM EQ+++ EQ+EK +++E++RE+E+R +E KMW+Q EK+RE
Sbjct: 56 MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM-REQKMWQQVEKMREKKK 114
Query: 442 -QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE-MWRQEEKIHEQEEIWRQKEKMH 499
QEEK++EQE+KM QEE + EQE EK QEQEE MW QE EKM
Sbjct: 115 TQEEKMQEQEEKMQEQEEMMWEQE-----EKMQEQEEKMWEQE-------------EKMR 156
Query: 500 EQEEKIRKQEEKVWRQEEKIREQE 523
EQEEK+R+QEEK+ QEEK+R+ E
Sbjct: 157 EQEEKMREQEEKMQGQEEKMRDVE 180
Score = 158 bits (399), Expect = 2e-38
Identities = 90/187 (48%), Positives = 130/187 (69%), Gaps = 20/187 (10%)
Query: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN--QQQEEK 301
++E +R ER K + ++++ E + +++Q K++ Q E ++W + Q+QEEK
Sbjct: 1 MREEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQ--EEKMWEQEEKMQEQEEK 55
Query: 302 MWRQEEKIQEWEEK------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR-- 353
MW QEEK+ E EEK + EQ+EK+ EQ+E++RE+EE+MR E+ MW++ EKMR
Sbjct: 56 MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMREKK 113
Query: 354 --QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ-EKIREQE 410
QEE M E+EEKM+ QEEMMWE+EEKM+ QEE MWE+EEK+RE EEKM EQ EK++ QE
Sbjct: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173
Query: 411 EKRQEEE 417
EK ++ E
Sbjct: 174 EKMRDVE 180
Score = 137 bits (345), Expect = 4e-32
Identities = 73/184 (39%), Positives = 125/184 (67%), Gaps = 16/184 (8%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
+E ++E+ K++E+ +++ ++ ++Q +E K + + K+ ++++Q + + + ++ +
Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE-----EKIRE----Q 326
+ + + E+ L +Q+EKMW Q+E+++E EE+++EQ+ EK+RE Q
Sbjct: 62 KMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
Query: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 386
EEK++EQEEKM+ QEEMMWE+EEKM+ QEE MWE+EEKMR QEE M E+EEKM+ QEE M
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 387 WEKE 390
+ E
Sbjct: 177 RDVE 180
Score = 108 bits (270), Expect = 2e-23
Identities = 63/190 (33%), Positives = 119/190 (62%), Gaps = 18/190 (9%)
Query: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
+++K R EE+ +E++ E +E+++E+ K+ E+ + ++ ++ ++ ++
Sbjct: 9 EREKKMREEEEMMREQEEKMQE------QEEKMREQEEKMWEQEEKMQEQEEKMW---EQ 59
Query: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306
++ E+ + + QQ+L + + + ++ + + K + ++ E ++W ++ + +E+K
Sbjct: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-EERMREQKMWQQVEKMREKK----- 113
Query: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
+ EEK+QEQEEK++EQEE + EQEEKM+ QEE MWE+EEKMR QEE M E+EEKM+
Sbjct: 114 ---KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170
Query: 367 RQEEMMWEKE 376
QEE M + E
Sbjct: 171 GQEEKMRDVE 180
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 216 bits (549), Expect = 8e-56
Identities = 154/498 (30%), Positives = 257/498 (51%), Gaps = 102/498 (20%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P + A+ +KKK+N G++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGAN--RKKKVN-GSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + GE R
Sbjct: 62 GYHSPGDSATGIY------------------------------------------GEGRA 79
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+ L D LE +A + I +LT+ ++L T +E K+
Sbjct: 80 SSTTLQD-------LESQYQELAVALDSSSAIISQLTENINSL-------VRTSKEEKKH 125
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--------QQLQAEADHLGKEL 274
L +KL K K + A+ L P+ +QLQ E +HL KEL
Sbjct: 126 EIHLVQKL------------GRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKEL 173
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
+SV +LQA+VE N++ + LN++QEE++ QEE++ E EE++ EQEE++ EQEE++ EQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQE 233
Query: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
E++R QEE + E+EE++ QEE + E+EE++ QEE + E +EK+ QE ++ E+ EK+
Sbjct: 234 ERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCE-QEKLPGQERLL-EEVEKLL 291
Query: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
E E + EQE++ E+E E E++ EQE+ ++Q+ ++W Q+E +RE E+
Sbjct: 292 EQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLW--------QQETLRELER--L 341
Query: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
R+ E++ E E++RE E+ E W E ++ Q+ + E++ + + +
Sbjct: 342 RELERLRELERLRELERMLELG--W---------EALYEQRAEPRSGFEELNNENKSTLQ 390
Query: 515 QEEKIREQEEKIREQEEK 532
E++++E E+ +E +
Sbjct: 391 LEQQVKELEKSGGAEEPR 408
Score = 149 bits (375), Expect = 1e-35
Identities = 94/301 (31%), Positives = 174/301 (57%), Gaps = 20/301 (6%)
Query: 397 EEKMHEQEKIREQEE-----KRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQE 450
EEK HE +++ K Q E + + + + + E +R++ E + Q
Sbjct: 121 EEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQL 180
Query: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE-IWRQKEKMHEQEEKIRKQE 509
+ + + + +EE R+++E + QEE++HEQEE + Q+E++ EQEE++R+QE
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQE 240
Query: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
E++ QEE++ EQEE++ EQEE++ QEE++ EQE++ +E + E EK+ E+E+RQE++
Sbjct: 241 ERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ 300
Query: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629
+++ +E + E EE + EQE RQ Q+E++W Q+E +RE E + E++R
Sbjct: 301 ERLLERERLLDEVEE--------LLEQERLRQ-QDERLW-QQETLRELER--LRELERLR 348
Query: 630 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689
E E++RE E M + E + EQ + E++ + ++ + E++++E EK +E
Sbjct: 349 EL-ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEP 407
Query: 690 K 690
+
Sbjct: 408 R 408
Score = 145 bits (366), Expect = 1e-34
Identities = 78/162 (48%), Positives = 120/162 (74%), Gaps = 17/162 (10%)
Query: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
RQEE++REQEE+ EQEE++ +QEE++ EQEE++ EQEE++REQEE++REQEE EQEE
Sbjct: 196 RQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEE 255
Query: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707
++ EQEE++CEQEE++ EQ EK+ QE ++ E+ EK+ EQE QE++E++ E
Sbjct: 256 RLCEQEERLCEQEERLCEQ--------EKLPGQE-RLLEEVEKLLEQER-RQEEQERLLE 305
Query: 708 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV-----RLRQQE 744
+E + E EE + ++E++R+Q+E++W+QE RLR+ E
Sbjct: 306 RERLLDEVEELL--EQERLRQQDERLWQQETLRELERLRELE 345
Score = 143 bits (361), Expect = 5e-34
Identities = 96/306 (31%), Positives = 171/306 (55%), Gaps = 50/306 (16%)
Query: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE-EKIRKQEEKVWRQE 516
E I+ + +EEK+ E IH +++ R K+ Q E + + +
Sbjct: 110 ENINSLVRTSKEEKKHE----------IHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKV 159
Query: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
E+++++ +R++ E + RQ + E +M + RQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR---------------------RQE 198
Query: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
E++REQEE++ QEE++ EQEE+ EQEE++ +QEE++REQEE+++EQEE++ EQEE++
Sbjct: 199 ERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLC 258
Query: 637 EQEEMTQEQEEKMGEQE-----EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
EQEE EQEE++ EQE E++ E+ EK+ EQE ++E++ E+E+ + E EE +
Sbjct: 259 EQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQ-EEQERLLERERLLDEVEELL 317
Query: 692 REQEEMMQEQEEKMWEQE-----EKMCEQE-----EKMQEQEEKMRRQEEKMWEQEVRLR 741
++E +++Q+E++W+QE E++ E E E+++E E + E ++EQ R
Sbjct: 318 --EQERLRQQDERLWQQETLRELERLRELERLRELERLRELERMLELGWEALYEQRAEPR 375
Query: 742 QQEEKM 747
E++
Sbjct: 376 SGFEEL 381
Score = 138 bits (348), Expect = 2e-32
Identities = 96/295 (32%), Positives = 175/295 (59%), Gaps = 28/295 (9%)
Query: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
+EEK HE +++ + + + E E + E++ ++ +RK+ E V RQ
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE-EEKMHEQE-KIWEEEKRQ-EQEDKM 572
+ E + + RQEE++REQEE E EE++HEQE ++ E+E+R EQE+++
Sbjct: 180 LQAEVENNQMLSLLNR---RQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERL 236
Query: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE-----EKIREQEEKIQEQEEK 627
QEE++REQEE++ QEE++ EQEE+ EQEE++ +QE E++ E+ EK+ EQE +
Sbjct: 237 REQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERR 296
Query: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE-----EKIREQEK 682
+E++E++ E+E + E EE + ++E++++Q+E +W+QE E++RE E
Sbjct: 297 -QEEQERLLERERLLDEVEELL---------EQERLRQQDERLWQQETLRELERLRELE- 345
Query: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
++RE E++RE E M++ E ++EQ + E++ + + + E+++ E E
Sbjct: 346 RLREL-ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELE 399
Score = 134 bits (338), Expect = 2e-31
Identities = 90/272 (33%), Positives = 164/272 (60%), Gaps = 22/272 (8%)
Query: 464 EKIREEEK--RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
E++++E R+E E + RQ + E ++ + QEE++R+QEE++ QEE++ E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR--RQEERLREQEERLHEQEERLHE 217
Query: 522 QEEKIREQEEKMWRQEEKIREQEEMWRE-EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
QEE++ EQEE++ QEE++REQEE RE EE++HEQ EE+ EQE+++ QEE++
Sbjct: 218 QEERLCEQEERLCEQEERLREQEERLREQEERLHEQ-----EERLCEQEERLCEQEERLC 272
Query: 581 EQE-----EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
EQE E++ + EK+ EQ E+RQE++E++ ++E + E EE + ++E++R+Q+E++
Sbjct: 273 EQEKLPGQERLLEEVEKLLEQ-ERRQEEQERLLERERLLDEVEELL--EQERLRQQDERL 329
Query: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
+QE T + E++ E E + E+++E E + E + EQ + R E++ +
Sbjct: 330 WQQE--TLRELERLRELER--LRELERLRELERMLELGWEALYEQRAEPRSGFEELNNEN 385
Query: 696 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
+ + E+++ E E+ +E + E R
Sbjct: 386 KSTLQLEQQVKELEKSGGAEEPRGSESAAAAR 417
Score = 131 bits (329), Expect = 3e-30
Identities = 98/360 (27%), Positives = 190/360 (52%), Gaps = 50/360 (13%)
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Q L+++ L L S SA + E R ++++++ +K+ K++ Q
Sbjct: 85 QDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQT 144
Query: 321 -EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM----RRQEEMMWEK 375
E + + + E+++ + + ++ E + RQ + E + + RRQEE + E+
Sbjct: 145 AEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQ 204
Query: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435
EE++ QEE + E+EE++ E EE++ EQE E R++EE++REQE
Sbjct: 205 EERLHEQEERLHEQEERLCEQEERLCEQE-----ERLREQEERLREQE------------ 247
Query: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
E++ EQEE++ EQE+++ QEE++ EQEK+ QE + + EK+ EQE ++
Sbjct: 248 -ERLHEQEERLCEQEERLCEQEERLCEQEKL------PGQERLLEEVEKLLEQERRQEEQ 300
Query: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE-----EKIREQEEMWREE 550
E++ E+E + + EE + ++E++R+Q+E++W+QE E++RE E + RE
Sbjct: 301 ERLLERERLLDEVEELL---------EQERLRQQDERLWQQETLRELERLRELERL-REL 350
Query: 551 EKMHEQEKI----WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
E++ E E++ WE Q E + +E + + + + E++++E E+ +E +
Sbjct: 351 ERLRELERMLELGWEALYEQRAEPRSGFEE--LNNENKSTLQLEQQVKELEKSGGAEEPR 408
Score = 126 bits (316), Expect = 8e-29
Identities = 77/210 (36%), Positives = 122/210 (58%), Gaps = 26/210 (12%)
Query: 551 EKMHEQEKIWEEEKRQEQE--DKMWRQEEKIREQEEKVWRQEEKIREQE-EKRQEQEEKM 607
E ++ + +EEK+ E K+ R K++ Q + E + E+ Q++ +
Sbjct: 110 ENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHL 169
Query: 608 WKQEEKIREQEEKIQEQEEKI----REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 663
K+ E + Q + E + + R QEE++REQEE EQEE++ EQEE++CEQEE++
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERL 229
Query: 664 QEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
EQEE ++REQEE++REQEE + EQEE++ EQEE++CEQEE++ EQE
Sbjct: 230 CEQEE--------------RLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQE 275
Query: 724 -----EKMRRQEEKMWEQEVRLRQQEEKMQ 748
E++ + EK+ EQE R +QE ++
Sbjct: 276 KLPGQERLLEEVEKLLEQERRQEEQERLLE 305
Score = 104 bits (260), Expect = 3e-22
Identities = 57/157 (36%), Positives = 101/157 (64%), Gaps = 6/157 (3%)
Query: 596 QEEKRQEQE--EKMWKQEEKIREQE-EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
+EEK+ E +K+ + K++ Q E + + + E+++++ +++ E +G Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 653 EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 712
+ E + + RQEE++REQE+++ EQEE++ EQEE + EQEE++ EQEE++
Sbjct: 180 LQAEVENNQMLSLLNR---RQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERL 236
Query: 713 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
EQEE+++EQEE++ QEE++ EQE RL +QEE++ E
Sbjct: 237 REQEERLREQEERLHEQEERLCEQEERLCEQEERLCE 273
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 201 bits (512), Expect = 2e-51
Identities = 148/620 (23%), Positives = 335/620 (54%), Gaps = 54/620 (8%)
Query: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
IS+ + F +Q AV +++K + E+TKE +S E+ L+EK
Sbjct: 1387 ISKKEEKKTFQKSPKQGRKAVQ-KERKVGKIKREMTKEERDMSEEVEEMAT----LEEKV 1441
Query: 224 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA 283
K + KL ++E S ++ K+ + K Q+ E K + K
Sbjct: 1442 VKQEGKLVMIERTPSW-----QDWKKAWDEWK------QVHGETRKSWKAWKEEWEKRLL 1490
Query: 284 QVEE--NELWNRLNQQ----QEEKMWRQEEKIQEWEEKI--QEQEEKIREQEEKIREQEE 335
Q EE ++ +L+ + QE+K + EE Q WE + + +E++ +++EE E+E
Sbjct: 1491 QEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEV 1550
Query: 336 KMRRQEEMMWEKEEKMRRQEEMMWEK--------EEKMRRQEEMMWEKEEKMRRQEEMMW 387
+E+ EE+ QEE W + E+K ++E + ++EEK+ ++E +
Sbjct: 1551 SREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLA 1610
Query: 388 EKEEKIRELEEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEA-KMWRQEEKIREQEE 444
++E K+ + K+ + ++ Q E + Q+EE + ++ ++ QEA K+ ++ +K+ ++ E
Sbjct: 1611 QEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWE 1670
Query: 445 KIREQEKKMWRQEEKIHEQEKIR----EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
K+ +E+K+ ++ K+ E + I EE ++EQ W+++E E EE+ E++
Sbjct: 1671 KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSW 1730
Query: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560
+EE++ ++E K+ +++K+ E+EE + Q EK+ +E K+ ++EE+ +E++ Q K
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK-- 1788
Query: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK-IREQEEKRQE-----QEEKMWKQEEKI 614
EK E+E+++ R+ E++ E++ K+ ++ E+ I EE + Q++ + ++++ +
Sbjct: 1789 --EKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNL 1846
Query: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
+++EK+ +++E + +E++ ++ + + K+G + + + EEK+ +++ET+ +++
Sbjct: 1847 AQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKK 1906
Query: 675 EKIREQEKKIREQEEKIREQEEMMQEQE-----EKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
EK+ E EKK+ + E+ + +++E + +++ EK Q +K E + ++E+ + +
Sbjct: 1907 EKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLE 1966
Query: 730 EEKMWEQEVRLRQQEEKMQE 749
+++ E+++RL + +E + +
Sbjct: 1967 MKRLAEEKMRLVEGKETLSK 1986
Score = 200 bits (509), Expect = 4e-51
Identities = 125/483 (25%), Positives = 278/483 (57%), Gaps = 24/483 (4%)
Query: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Q + E+ R ++Q +K R ++E + +++ ++ I + + +E +++E
Sbjct: 1334 QEVIRHKEVMPR-EEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEE 1392
Query: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 401
+ ++K K R+ +KE K+ + + M ++E M + E M EEK+ + E K+
Sbjct: 1393 KKTFQKSPKQGRKAV---QKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLV 1449
Query: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE--EKIREQEEKIREQEKKMWRQEEK 459
E+ ++ ++ ++ ++ + K W++E +++ ++EEK+ + +K+ +EE
Sbjct: 1450 MIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEM 1509
Query: 460 IHEQEKIREEEKRQ---------EQEEMWRQEEKIHEQEEIWRQKEKMHEQ--EEKIRKQ 508
+ E +K++ EE +Q +E+ ++ EE++ +EE+ R+ E+ +Q EE+ Q
Sbjct: 1510 LQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQ 1569
Query: 509 EEKVWRQEEKIREQEEKIREQEE-KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
EE W + + R + EK R QEE K+ ++EEK+ ++E +EE+ Q + K +
Sbjct: 1570 EEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYV----KITQ 1625
Query: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
+ +M + E K ++EE + ++ EK+ ++ EK ++ +K+ K+ EK+ +EEK+ ++ K
Sbjct: 1626 DDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGK 1685
Query: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ-EQEETMWRQEEKIREQEKKIRE 686
+ E + + ++ E ++E+ + QE+++ ++ E+++ + EE W++EE + ++E K+ E
Sbjct: 1686 LAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEE-LNQEEGKLVE 1744
Query: 687 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
+++K+ E+EE + Q EK+ E+E K+ ++EE + +++EK+ + +EKM E+E RL ++ E+
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQ 1804
Query: 747 MQE 749
+ E
Sbjct: 1805 LIE 1807
Score = 196 bits (497), Expect = 9e-50
Identities = 130/542 (23%), Positives = 299/542 (55%), Gaps = 31/542 (5%)
Query: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
E+L + LQE +L E ++ N+ K K ++ K + L+ E G+E +
Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE-EEVTLEEEVSREGEEKEQ 1559
Query: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
+ Q ++E W R+++++ E+K ++E K+ ++EEK+ ++E +
Sbjct: 1560 QVTEEQRHIQEEHKWARIHRKRARA-----------EKKRAQEERKLAQEEEKLAQEERQ 1608
Query: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
+ ++E + + K+ + + M + E K ++EE + ++ EK+ ++ E + +K +K+ +
Sbjct: 1609 LAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKK 1668
Query: 397 EEKM-HEQEKIREQEEKRQEEEKI---REQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
EK+ E+EK+ ++ K E + I + +E Q ++ W+++E +E EE + E+
Sbjct: 1669 WEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEEL 1728
Query: 453 MWRQEEKIHEQEKIREEEKR--QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
W++EE E+ K+ EE+K+ +E+E + Q EK+ E+E K+ ++EE + +++E
Sbjct: 1729 SWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEE------TKLAQEEELLIQEKE 1782
Query: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW-REEEKMHEQEKIWEEEKRQEQE 569
K+ + +EK+ E+EE++ + E++ ++ K+ ++ E W E++ + + I ++K QE
Sbjct: 1783 KLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQE 1842
Query: 570 DKMWRQE-EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
K QE EK+ +++E + +E++ +++ + + K+ + + + EEK+ +++E +
Sbjct: 1843 KKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETV 1902
Query: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
+++EK+ E E+ + E+ + +++EK+ +EKM+ E Q +K E I ++E
Sbjct: 1903 IKKKEKLAETEKKLVQVEDSLAKKQEKLA--QEKMKLALEKAMVQGKKRLRGELDIAKEE 1960
Query: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
+ + + + + E++ ++ E +E + + E ++ KM + E++++E+++ L EEK+
Sbjct: 1961 KALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSL---EEKIL 2017
Query: 749 EH 750
H
Sbjct: 2018 LH 2019
Score = 186 bits (471), Expect = 9e-47
Identities = 152/666 (22%), Positives = 341/666 (51%), Gaps = 97/666 (14%)
Query: 177 LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL-QEKLQLVES 235
L Q + + +++ D +EL +E + L ++ + +EEL ++ KL +EK +L E
Sbjct: 1693 LAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEE 1752
Query: 236 EKS-----------EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
E++ E +L +E E+ KL ++++ E + LG++ + + K
Sbjct: 1753 EEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKL 1812
Query: 285 VEENELW-NRLNQQQEEKMWRQEEKIQEWEEK-IQEQEEKIREQEEKIREQEEKMRRQEE 342
++ E W N + + + KM ++K E+K + +++EK+ +++E + +E++ ++
Sbjct: 1813 AQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKK 1872
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 402
+ + + K+ +++ + EEK+ +++E + +K+EK+ E+ + + E+ + + +EK+ +
Sbjct: 1873 QLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQ 1932
Query: 403 Q------EKIREQEEKR--------QEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIR 447
+ EK Q +KR +EE+ + + KR E++ ++ +E + + E
Sbjct: 1933 EKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPET 1992
Query: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK----------------IHEQEEI 491
+++KM + E+++ E++ EE+ ++ + EE + Q ++
Sbjct: 1993 SRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKL 2052
Query: 492 WRQKEKMHEQEE----------KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI- 540
+ K+ ++ E KI K +K+ R E K+ ++E K+ + + ++ +E ++
Sbjct: 2053 AKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLS 2112
Query: 541 --------------REQEEMWREEEKMHEQEK---------IWEEEKRQEQEDKMWRQE- 576
++ E+ ++E+K+ +++ I +EEK E+E K+ R+
Sbjct: 2113 IEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHS 2172
Query: 577 EKIREQEEKVWRQEEKI----------REQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626
E I + EE+ +EE++ R++ ++ + +EK Q +++ +E +E E
Sbjct: 2173 EVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMES 2232
Query: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686
+ E E++ E +E+EE+ +EE++ E+EE+ +E+EE +Q EK E+EKK ++
Sbjct: 2233 LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK-EEEEKKKKK 2291
Query: 687 QE---EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 743
+E E+++E+EE+ +E+EE M E+E + EE E+EE +EE E+E+ +++
Sbjct: 2292 KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEE---EEEESCSLEEEVDREKEILKKEK 2348
Query: 744 EEKMQE 749
+ K+QE
Sbjct: 2349 QFKLQE 2354
Score = 152 bits (384), Expect = 1e-36
Identities = 146/614 (23%), Positives = 308/614 (50%), Gaps = 68/614 (11%)
Query: 107 PEDEQKASHQHQEALRRELEAQVHTIRILTCQK--TELQMALYYSQHAV---KQLEGEAR 161
PE+E++ + ++ + ++++ R + + T+ +M LY ++ K L E
Sbjct: 1792 PEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851
Query: 162 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
L R + L + + K K + + L + + L+ E + T+ + KE
Sbjct: 1852 KLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQE--KETVIKK--KE 1907
Query: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP-QQQLQAEADHLGKELQSVSAK 280
K A+ ++KL VE ++ Q + + K KL K ++ +++L+ E D + KE ++++ +
Sbjct: 1908 KLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELD-IAKEEKALNLE 1966
Query: 281 LQAQVEEN----ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ---EEKIREQEEKIREQ 333
++ EE E L++ + + RQ + Q +E + + EEKI E++I
Sbjct: 1967 MKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAM 2026
Query: 334 EE--------KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM---WEKEEKMRRQ 382
EE + R + + + + K+ + + +K E + ++ + + +K+ R
Sbjct: 2027 EESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRD 2086
Query: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
E + ++E K+ +++ + +E+ E+ + + ++ EKR E + + E+K+ +
Sbjct: 2087 ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSE----LTKDEKKLARK 2142
Query: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK--IHEQEEIWRQKEKMHE 500
+ K+ + ++M +EEK+ E+E + R+ E + EE+ I E+E I K + +
Sbjct: 2143 QRKLANKMRRMINKEEKMTEEES---KLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRK 2199
Query: 501 QEEKIR--KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
++E R K +EK Q +++ E EE E+ E + + EK QE + EEE+ E+E+
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEV-ESEEHFSEEMESLLDELEK---QESLSSEEEEEREEEE 2255
Query: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
EEE+ +E+E++ R+EE+ E+++ +E+EEK K++EK ++
Sbjct: 2256 EREEEEVREEEEE----------------RKEEEEGEEKQVEKEEEEKKKKKKEK---KK 2296
Query: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE-KI 677
E++QE+EE E+EE + E+E + E E+EE+ C EE++ ++E + ++++ K+
Sbjct: 2297 EEVQEKEEVFEEKEEIMSEEETESLSDE----EEEEESCSLEEEVDREKEILKKEKQFKL 2352
Query: 678 REQEKKIREQEEKI 691
+EQ +K E++
Sbjct: 2353 QEQRRKSLRGRERV 2366
Score = 109 bits (273), Expect = 8e-24
Identities = 135/663 (20%), Positives = 279/663 (42%), Gaps = 140/663 (21%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHL----G 271
DE ++ K L ++ + S S +QL K+ E + + Q + DHL
Sbjct: 967 DERVRIKTLSLMAEIG-IHSRTSLLQLTQKQ-----ETFREMQQQMIGEEPLDHLLGMRA 1020
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
+LQ +S +++ ++ EN L+ + E+ + + + E K + + E+ E
Sbjct: 1021 TDLQILSTQVEQRLNENLT---LSHRDEKPAFSLDVSMPS-ELKSSLKPPTVSEESEVAI 1076
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--------EKMRRQE 383
+ + RR + + + +K R + E++ K E + E E E
Sbjct: 1077 KPSKGQRRGQAGVKKHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAPIEMEEASV 1136
Query: 384 EMMWEKEEKIRELEEKMHEQEK----------------IREQEEKRQEEEKIREQEKRQE 427
W + +L + + QEK IR++ +K+ +K++++ K++
Sbjct: 1137 YSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKKG 1196
Query: 428 QEAKMWRQEEKIREQEEKIREQEK-------------------KMWRQE----------- 457
+EAK+ +E E+ + ++ K WR +
Sbjct: 1197 KEAKVINEETTPPVMEQPVTKKVKIQGRGASGISGRRSTAGDGSSWRDDLCRLMALRISG 1256
Query: 458 ------EKIHEQEKIREEEKRQEQEEMW----------RQEEKIHEQEEIW----RQKEK 497
E ++ + +E ++ W ++E K+ ++ W +K+
Sbjct: 1257 SQTKMSENLNAELVTFAQEMLVDRHPSWELFQEICPLLKKESKVLLEDLDWDVVPPEKKP 1316
Query: 498 MHEQEEKIRKQ-----EEKVWRQEEKIREQEEKIREQEEKMWRQEE-------------- 538
+ QE IR+ ++V R +E + +EE+ +++ M EE
Sbjct: 1317 IFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFL 1376
Query: 539 ---KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK-------MWRQEEKIREQEEKVWR 588
+ +E+ ++EEK Q+ + K ++E K M ++E + E+ E++
Sbjct: 1377 EPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMAT 1436
Query: 589 QEEKIREQEEK--------RQEQEEKMWKQEEKI------------REQEEKIQEQEEKI 628
EEK+ +QE K + +K W + +++ E E+++ ++EEK+
Sbjct: 1437 LEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKL 1496
Query: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
+ EK+ +EEM QE ++K+ +E K + + +E ++ EE++ +E+ RE E
Sbjct: 1497 HQAGEKLSPEEEMLQE-DKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGE 1555
Query: 689 EKIRE-QEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
EK ++ EE QEE W + K E+K ++E K+ ++EEK+ ++E +L Q+E K
Sbjct: 1556 EKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERK 1615
Query: 747 MQE 749
+ +
Sbjct: 1616 LAQ 1618
Score = 50.1 bits (118), Expect = 8e-06
Identities = 62/279 (22%), Positives = 132/279 (47%), Gaps = 41/279 (14%)
Query: 140 TELQMALYYSQHAVK----QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYI 195
T+++ AL+ + + +L+ + D + + K +L + +A + ++
Sbjct: 2098 TKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKE 2157
Query: 196 EELTKERDALSLELYRNTITDEE-----------------LKEKNAKLQEK--------L 230
E++T+E L+ + + DEE K K AK +K +
Sbjct: 2158 EKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQV 2217
Query: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 290
VESE+ ++ L +LE+ + L +++ + E + +E + V + + + EE E
Sbjct: 2218 DEVESEE-HFSEEMESLLDELEKQESLSSEEEEEREEEE-EREEEEVREEEEERKEEEEG 2275
Query: 291 WNRLNQQQEEKMW--RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
++Q EK ++++K ++ +E++QE+EE E+EE + E+E + EE E+E
Sbjct: 2276 ----EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEE---EEE 2328
Query: 349 EKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRQEEMM 386
E +EE+ EKE K +Q ++ ++ + +R +E ++
Sbjct: 2329 ESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVL 2367
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 174 bits (442), Expect = 2e-43
Identities = 134/449 (29%), Positives = 222/449 (49%), Gaps = 104/449 (23%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P + A+ +KKK+N G++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGAN--RKKKVN-GSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + GE R
Sbjct: 62 GYHSPGDSATGIY------------------------------------------GEGRA 79
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+ L D LE +A + I +LT+ ++L T +E K+
Sbjct: 80 SSTTLQD-------LESQYQELAVALDSSSAIISQLTENINSL-------VRTSKEEKKH 125
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--------QQLQAEADHLGKEL 274
L +KL K K + A+ L PQ +QLQ E +HL KEL
Sbjct: 126 EIHLVQKL------------GRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKEL 173
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
+SV +LQA+VE N++ + LN++QEE++ QEE+++E EE++ EQEE++ EQEE++REQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQE 233
Query: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
E++ Q EK+ QE ++ E E+ + K+E+ + ++E + E+E +
Sbjct: 234 ERLCEQ--------EKLPGQERLLEEVEKLL---------KQERRQEEQERLLERERLLD 276
Query: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE-------AKMWRQEEKIREQEEKIR 447
E+EE + EQE++R+Q+E+ ++E +RE E+ +E E ++ Q + R E++
Sbjct: 277 EVEELL-EQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELN 335
Query: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
+ K + E+++ E EK E+ + E
Sbjct: 336 NENKSTLQLEQQVKELEKSGGAEEPRGSE 364
Score = 107 bits (268), Expect = 3e-23
Identities = 69/224 (30%), Positives = 132/224 (58%), Gaps = 15/224 (6%)
Query: 464 EKIREEEK--RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
E++++E R+E E + RQ + E ++ + QEE++R+QEE++ QEE++ E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR--RQEERLREQEERLREQEERLCE 217
Query: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
QEE++ EQEE++ QEE++ EQE++ +E + E EK+ ++E+RQE+++++ +E + E
Sbjct: 218 QEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDE 277
Query: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
EE + EQE RQ Q+E++W Q+E +RE E+++E E + E + EQ
Sbjct: 278 VEE--------LLEQERLRQ-QDERLW-QQETLREL-ERLRELERMLELGWEALYEQRAE 326
Query: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR 685
+ E++ + + + E++++E E++ +E + E R
Sbjct: 327 PRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSESAAAAR 370
Score = 105 bits (261), Expect = 2e-22
Identities = 79/286 (27%), Positives = 152/286 (53%), Gaps = 49/286 (17%)
Query: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE-EKIRKQEEKVWRQE 516
E I+ + +EEK+ E IH +++ R K+ Q E + Q +
Sbjct: 110 ENINSLVRTSKEEKKHE----------IHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKV 159
Query: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
E+++++ +R++ E + RQ + E +M + RQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR---------------------RQE 198
Query: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
E++REQEE+ +REQEE+ EQEE++ +QEE++REQEE++ EQ EK+ QE +
Sbjct: 199 ERLREQEER-------LREQEERLCEQEERLCEQEERLREQEERLCEQ-EKLPGQERLLE 250
Query: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE-----EKI 691
E E++ ++E+ E++E++ E+E + E EE + ++E++R+Q++++ +QE E++
Sbjct: 251 EVEKLL--KQERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLRELERL 306
Query: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
RE E M++ E ++EQ + E++ + + + E+++ E E
Sbjct: 307 RELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELE 352
Score = 103 bits (258), Expect = 4e-22
Identities = 68/214 (31%), Positives = 122/214 (57%), Gaps = 25/214 (11%)
Query: 551 EKMHEQEKIWEEEKRQEQE--DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
E ++ + +EEK+ E K+ R K++ Q E + Q + E++
Sbjct: 110 ENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTA------EPLAPQPPAGPSKVEQLQ 163
Query: 609 KQEEKIREQEEKIQEQEEKIREQEEKI----REQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
+ +R++ E + Q + E + + R QEE +EQEE++ EQEE++CEQEE++
Sbjct: 164 DETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLC 223
Query: 665 EQEETMWRQEEKIREQEK-----KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
EQEE + QEE++ EQEK ++ E+ EK+ +QE QE++E++ E+E + E EE +
Sbjct: 224 EQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQER-RQEEQERLLERERLLDEVEELL 282
Query: 720 QEQEEKMRRQEEKMWEQEV-----RLRQQEEKMQ 748
++E++R+Q+E++W+QE RLR+ E ++
Sbjct: 283 --EQERLRQQDERLWQQETLRELERLRELERMLE 314
Score = 102 bits (253), Expect = 2e-21
Identities = 66/261 (25%), Positives = 136/261 (52%), Gaps = 23/261 (8%)
Query: 397 EEKMHEQEKIREQEE-----KRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQE 450
EEK HE +++ K Q E + Q + + + E +R++ E + Q
Sbjct: 121 EEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQL 180
Query: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
+ + + + +EE R+++E + QEE++ EQE E++ EQEE++R+QEE
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE------ERLCEQEERLREQEE 234
Query: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
++ QE+ +E++ E+ EK+ +QE + EQE + E + E E++ E+E+ ++Q++
Sbjct: 235 RLCEQEK--LPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDE 292
Query: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
++W+QE R+ E++RE E + E +++Q + R E++ + + +
Sbjct: 293 RLWQQE---------TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQ 343
Query: 631 QEEKIREQEEMTQEQEEKMGE 651
E++++E E+ +E + E
Sbjct: 344 LEQQVKELEKSGGAEEPRGSE 364
Score = 99.8 bits (247), Expect = 8e-21
Identities = 82/297 (27%), Positives = 156/297 (52%), Gaps = 28/297 (9%)
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Q L+++ L L S SA + +Q+ EN N L + +E+ + +Q K+
Sbjct: 85 QDLESQYQELAVALDSSSAII-SQLTENI--NSLVRTSKEEKKHEIHLVQ----KLGRSL 137
Query: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM- 379
K++ Q E + Q K E+++ + + ++ E + RQ + E + +
Sbjct: 138 FKLKNQTA------EPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLS 191
Query: 380 ---RRQEEMMWEKEEKIRELEEKMHEQ-EKIREQEEK-RQEEEKIREQEKRQEQEAKMWR 434
RRQEE + E+EE++RE EE++ EQ E++ EQEE+ R++EE++ EQEK Q
Sbjct: 192 LLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQ------ 245
Query: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494
E++ E+ EK+ +QE++ QE + + + E E+ EQE + +Q+E++ +QE + R+
Sbjct: 246 --ERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETL-RE 302
Query: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
E++ E E + E ++ Q + R E++ + + + E++++E E+ EE
Sbjct: 303 LERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 359
Score = 97.1 bits (240), Expect = 5e-20
Identities = 62/201 (30%), Positives = 116/201 (57%), Gaps = 14/201 (6%)
Query: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEE-----KRQEEEKIREQEKR-QEQEAKMWRQE 436
E++ E +ELE + + E + R++EE++REQE+R +EQE ++ QE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219
Query: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
E++ EQEE++REQE+++ QE+ ++ + E EK +QE ++E++ E+E + + E
Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVE 279
Query: 497 KMHEQEEKIRKQEEKVWRQE-----EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
++ EQ E++R+Q+E++W+QE E++RE E + E ++ Q + R E E
Sbjct: 280 ELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNEN 338
Query: 552 K--MHEQEKIWEEEKRQEQED 570
K + ++++ E EK E+
Sbjct: 339 KSTLQLEQQVKELEKSGGAEE 359
Score = 95.9 bits (237), Expect = 1e-19
Identities = 63/219 (28%), Positives = 124/219 (56%), Gaps = 19/219 (8%)
Query: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKIREQEEKIRE 448
K+ +L+++ + K E ++ + E Q + QE ++ QEE++REQEE++ E
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCE 217
Query: 449 QEKKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK 507
QE+++ QEE++ EQE ++ E+EK QE + + EK+ +QE ++E++ E+E + +
Sbjct: 218 QEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDE 277
Query: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
EE + ++E++R+Q+E++W Q+E +RE E + RE E+M E WE Q
Sbjct: 278 VEELL---------EQERLRQQDERLW-QQETLRELERL-RELERMLELG--WEALYEQR 324
Query: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
E + +E + + + + E++++E E+ +E +
Sbjct: 325 AEPRSGFEE--LNNENKSTLQLEQQVKELEKSGGAEEPR 361
Score = 95.9 bits (237), Expect = 1e-19
Identities = 69/251 (27%), Positives = 129/251 (51%), Gaps = 45/251 (17%)
Query: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
E++ ++ +RK+ E V RQ + E + + RQEE++REQEE RE+E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR---RQEERLREQEERLREQE---- 212
Query: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
E+ EQE+++ QEE++REQEE++ QE+ +E+ E+ EK+ KQE +
Sbjct: 213 -------ERLCEQEERLCEQEERLREQEERLCEQEK--LPGQERLLEEVEKLLKQERR-- 261
Query: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE- 674
QE++E++ E+E + E EE+ ++E++++Q+E +W+QE
Sbjct: 262 ------QEEQERLLERERLLDEVEELL----------------EQERLRQQDERLWQQET 299
Query: 675 ----EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
E++RE E+ + E + EQ + E++ + + + E++++E E+ +E
Sbjct: 300 LRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 359
Query: 731 EKMWEQEVRLR 741
+ E R
Sbjct: 360 PRGSESAAAAR 370
Score = 62.8 bits (151), Expect = 1e-09
Identities = 39/134 (29%), Positives = 73/134 (54%), Gaps = 5/134 (3%)
Query: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE-EKMQEQEETMWRQEEKIRE 679
I + E I +E+++ +K+G K+ Q E + Q + E++++
Sbjct: 105 ISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQD 164
Query: 680 QEKKIREQEEKIREQEEMMQEQEEKMW----EQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
+ +R++ E + Q + E + + QEE++ EQEE+++EQEE++ QEE++ E
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCE 224
Query: 736 QEVRLRQQEEKMQE 749
QE RLR+QEE++ E
Sbjct: 225 QEERLREQEERLCE 238
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 174 bits (442), Expect = 2e-43
Identities = 134/449 (29%), Positives = 222/449 (49%), Gaps = 104/449 (23%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P + A+ +KKK+N G++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGAN--RKKKVN-GSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + GE R
Sbjct: 62 GYHSPGDSATGIY------------------------------------------GEGRA 79
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+ L D LE +A + I +LT+ ++L T +E K+
Sbjct: 80 SSTTLQD-------LESQYQELAVALDSSSAIISQLTENINSL-------VRTSKEEKKH 125
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--------QQLQAEADHLGKEL 274
L +KL K K + A+ L PQ +QLQ E +HL KEL
Sbjct: 126 EIHLVQKL------------GRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKEL 173
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
+SV +LQA+VE N++ + LN++QEE++ QEE+++E EE++ EQEE++ EQEE++REQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQE 233
Query: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
E++ Q EK+ QE ++ E E+ + K+E+ + ++E + E+E +
Sbjct: 234 ERLCEQ--------EKLPGQERLLEEVEKLL---------KQERRQEEQERLLERERLLD 276
Query: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE-------AKMWRQEEKIREQEEKIR 447
E+EE + EQE++R+Q+E+ ++E +RE E+ +E E ++ Q + R E++
Sbjct: 277 EVEELL-EQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELN 335
Query: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
+ K + E+++ E EK E+ + E
Sbjct: 336 NENKSTLQLEQQVKELEKSGGAEEPRGSE 364
Score = 107 bits (268), Expect = 3e-23
Identities = 69/224 (30%), Positives = 132/224 (58%), Gaps = 15/224 (6%)
Query: 464 EKIREEEK--RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
E++++E R+E E + RQ + E ++ + QEE++R+QEE++ QEE++ E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR--RQEERLREQEERLREQEERLCE 217
Query: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
QEE++ EQEE++ QEE++ EQE++ +E + E EK+ ++E+RQE+++++ +E + E
Sbjct: 218 QEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDE 277
Query: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
EE + EQE RQ Q+E++W Q+E +RE E+++E E + E + EQ
Sbjct: 278 VEE--------LLEQERLRQ-QDERLW-QQETLREL-ERLRELERMLELGWEALYEQRAE 326
Query: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR 685
+ E++ + + + E++++E E++ +E + E R
Sbjct: 327 PRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSESAAAAR 370
Score = 105 bits (261), Expect = 2e-22
Identities = 79/286 (27%), Positives = 152/286 (53%), Gaps = 49/286 (17%)
Query: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE-EKIRKQEEKVWRQE 516
E I+ + +EEK+ E IH +++ R K+ Q E + Q +
Sbjct: 110 ENINSLVRTSKEEKKHE----------IHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKV 159
Query: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
E+++++ +R++ E + RQ + E +M + RQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR---------------------RQE 198
Query: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
E++REQEE+ +REQEE+ EQEE++ +QEE++REQEE++ EQ EK+ QE +
Sbjct: 199 ERLREQEER-------LREQEERLCEQEERLCEQEERLREQEERLCEQ-EKLPGQERLLE 250
Query: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE-----EKI 691
E E++ ++E+ E++E++ E+E + E EE + ++E++R+Q++++ +QE E++
Sbjct: 251 EVEKLL--KQERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLRELERL 306
Query: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
RE E M++ E ++EQ + E++ + + + E+++ E E
Sbjct: 307 RELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELE 352
Score = 103 bits (258), Expect = 4e-22
Identities = 68/214 (31%), Positives = 122/214 (57%), Gaps = 25/214 (11%)
Query: 551 EKMHEQEKIWEEEKRQEQE--DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
E ++ + +EEK+ E K+ R K++ Q E + Q + E++
Sbjct: 110 ENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTA------EPLAPQPPAGPSKVEQLQ 163
Query: 609 KQEEKIREQEEKIQEQEEKIREQEEKI----REQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
+ +R++ E + Q + E + + R QEE +EQEE++ EQEE++CEQEE++
Sbjct: 164 DETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLC 223
Query: 665 EQEETMWRQEEKIREQEK-----KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
EQEE + QEE++ EQEK ++ E+ EK+ +QE QE++E++ E+E + E EE +
Sbjct: 224 EQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQER-RQEEQERLLERERLLDEVEELL 282
Query: 720 QEQEEKMRRQEEKMWEQEV-----RLRQQEEKMQ 748
++E++R+Q+E++W+QE RLR+ E ++
Sbjct: 283 --EQERLRQQDERLWQQETLRELERLRELERMLE 314
Score = 102 bits (253), Expect = 2e-21
Identities = 66/261 (25%), Positives = 136/261 (52%), Gaps = 23/261 (8%)
Query: 397 EEKMHEQEKIREQEE-----KRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQE 450
EEK HE +++ K Q E + Q + + + E +R++ E + Q
Sbjct: 121 EEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQL 180
Query: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
+ + + + +EE R+++E + QEE++ EQE E++ EQEE++R+QEE
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE------ERLCEQEERLREQEE 234
Query: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
++ QE+ +E++ E+ EK+ +QE + EQE + E + E E++ E+E+ ++Q++
Sbjct: 235 RLCEQEK--LPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDE 292
Query: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
++W+QE R+ E++RE E + E +++Q + R E++ + + +
Sbjct: 293 RLWQQE---------TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQ 343
Query: 631 QEEKIREQEEMTQEQEEKMGE 651
E++++E E+ +E + E
Sbjct: 344 LEQQVKELEKSGGAEEPRGSE 364
Score = 99.8 bits (247), Expect = 8e-21
Identities = 82/297 (27%), Positives = 156/297 (52%), Gaps = 28/297 (9%)
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Q L+++ L L S SA + +Q+ EN N L + +E+ + +Q K+
Sbjct: 85 QDLESQYQELAVALDSSSAII-SQLTENI--NSLVRTSKEEKKHEIHLVQ----KLGRSL 137
Query: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM- 379
K++ Q E + Q K E+++ + + ++ E + RQ + E + +
Sbjct: 138 FKLKNQTA------EPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLS 191
Query: 380 ---RRQEEMMWEKEEKIRELEEKMHEQ-EKIREQEEK-RQEEEKIREQEKRQEQEAKMWR 434
RRQEE + E+EE++RE EE++ EQ E++ EQEE+ R++EE++ EQEK Q
Sbjct: 192 LLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQ------ 245
Query: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494
E++ E+ EK+ +QE++ QE + + + E E+ EQE + +Q+E++ +QE + R+
Sbjct: 246 --ERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETL-RE 302
Query: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
E++ E E + E ++ Q + R E++ + + + E++++E E+ EE
Sbjct: 303 LERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 359
Score = 97.1 bits (240), Expect = 5e-20
Identities = 62/201 (30%), Positives = 116/201 (57%), Gaps = 14/201 (6%)
Query: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEE-----KRQEEEKIREQEKR-QEQEAKMWRQE 436
E++ E +ELE + + E + R++EE++REQE+R +EQE ++ QE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219
Query: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
E++ EQEE++REQE+++ QE+ ++ + E EK +QE ++E++ E+E + + E
Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVE 279
Query: 497 KMHEQEEKIRKQEEKVWRQE-----EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
++ EQ E++R+Q+E++W+QE E++RE E + E ++ Q + R E E
Sbjct: 280 ELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNEN 338
Query: 552 K--MHEQEKIWEEEKRQEQED 570
K + ++++ E EK E+
Sbjct: 339 KSTLQLEQQVKELEKSGGAEE 359
Score = 95.9 bits (237), Expect = 1e-19
Identities = 63/219 (28%), Positives = 124/219 (56%), Gaps = 19/219 (8%)
Query: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKIREQEEKIRE 448
K+ +L+++ + K E ++ + E Q + QE ++ QEE++REQEE++ E
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCE 217
Query: 449 QEKKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK 507
QE+++ QEE++ EQE ++ E+EK QE + + EK+ +QE ++E++ E+E + +
Sbjct: 218 QEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDE 277
Query: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
EE + ++E++R+Q+E++W Q+E +RE E + RE E+M E WE Q
Sbjct: 278 VEELL---------EQERLRQQDERLW-QQETLRELERL-RELERMLELG--WEALYEQR 324
Query: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
E + +E + + + + E++++E E+ +E +
Sbjct: 325 AEPRSGFEE--LNNENKSTLQLEQQVKELEKSGGAEEPR 361
Score = 95.9 bits (237), Expect = 1e-19
Identities = 69/251 (27%), Positives = 129/251 (51%), Gaps = 45/251 (17%)
Query: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
E++ ++ +RK+ E V RQ + E + + RQEE++REQEE RE+E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR---RQEERLREQEERLREQE---- 212
Query: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
E+ EQE+++ QEE++REQEE++ QE+ +E+ E+ EK+ KQE +
Sbjct: 213 -------ERLCEQEERLCEQEERLREQEERLCEQEK--LPGQERLLEEVEKLLKQERR-- 261
Query: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE- 674
QE++E++ E+E + E EE+ ++E++++Q+E +W+QE
Sbjct: 262 ------QEEQERLLERERLLDEVEELL----------------EQERLRQQDERLWQQET 299
Query: 675 ----EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
E++RE E+ + E + EQ + E++ + + + E++++E E+ +E
Sbjct: 300 LRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 359
Query: 731 EKMWEQEVRLR 741
+ E R
Sbjct: 360 PRGSESAAAAR 370
Score = 62.8 bits (151), Expect = 1e-09
Identities = 39/134 (29%), Positives = 73/134 (54%), Gaps = 5/134 (3%)
Query: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE-EKMQEQEETMWRQEEKIRE 679
I + E I +E+++ +K+G K+ Q E + Q + E++++
Sbjct: 105 ISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQD 164
Query: 680 QEKKIREQEEKIREQEEMMQEQEEKMW----EQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
+ +R++ E + Q + E + + QEE++ EQEE+++EQEE++ QEE++ E
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCE 224
Query: 736 QEVRLRQQEEKMQE 749
QE RLR+QEE++ E
Sbjct: 225 QEERLREQEERLCE 238
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 169 bits (427), Expect = 1e-41
Identities = 131/449 (29%), Positives = 220/449 (48%), Gaps = 104/449 (23%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P + A+ +KKK+N G++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGAN--RKKKVN-GSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + GE R
Sbjct: 62 GYHSPGDSATGIY------------------------------------------GEGRA 79
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+ L D LE +A + I +LT+ ++L T +E K+
Sbjct: 80 SSTTLQD-------LESQYQELAVALDSSSAIISQLTENINSL-------VRTSKEEKKH 125
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--------QQLQAEADHLGKEL 274
L +KL K K + A+ L P+ +QLQ E +HL KEL
Sbjct: 126 EIHLVQKL------------GRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKEL 173
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
+SV +LQA+VE N++ + LN++QEE++ +EQEE++REQEE++ EQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERL--------------REQEERLREQEERLHEQE 219
Query: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
E++ QEE + E+EE++ QE++ +E++ + E + E+E + QE ++ E+E +
Sbjct: 220 ERLCEQEERLCEQEERLCEQEKL--PGQERLLEEVEKLLEQERRQEEQERLL-ERERLLD 276
Query: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE-------AKMWRQEEKIREQEEKIR 447
E+EE + EQE++R+Q+E+ ++E +RE E+ +E E ++ Q + R E++
Sbjct: 277 EVEELL-EQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELN 335
Query: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQE 476
+ K + E+++ E EK E+ + E
Sbjct: 336 NENKSTLQLEQQVKELEKSGGAEEPRGSE 364
Score = 110 bits (276), Expect = 4e-24
Identities = 70/224 (31%), Positives = 132/224 (58%), Gaps = 15/224 (6%)
Query: 464 EKIREEEK--RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
E++++E R+E E + RQ + E ++ + QEE++R+QEE++ QEE++ E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR--RQEERLREQEERLREQEERLHE 217
Query: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
QEE++ EQEE++ QEE++ EQE++ +E + E EK+ E+E+RQE+++++ +E + E
Sbjct: 218 QEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDE 277
Query: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
EE + EQE RQ Q+E++W Q+E +RE E+++E E + E + EQ
Sbjct: 278 VEE--------LLEQERLRQ-QDERLW-QQETLREL-ERLRELERMLELGWEALYEQRAE 326
Query: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR 685
+ E++ + + + E++++E E++ +E + E R
Sbjct: 327 PRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSESAAAAR 370
Score = 104 bits (260), Expect = 3e-22
Identities = 70/275 (25%), Positives = 152/275 (55%), Gaps = 31/275 (11%)
Query: 393 IRELEEKMHEQEKIREQEEKRQEE--EKI-REQEKRQEQEAKMWRQE--------EKIRE 441
I +L E ++ + ++E+K + +K+ R K + Q A+ E E++++
Sbjct: 105 ISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQD 164
Query: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501
+ +R++ + + RQ + E ++ R+++E + QEE++ EQEE ++HEQ
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEE------RLHEQ 218
Query: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561
EE++ +QEE++ QEE++ EQE+ +E++ + EK+ EQE E+E++ E+E++ +
Sbjct: 219 EERLCEQEERLCEQEERLCEQEKL--PGQERLLEEVEKLLEQERRQEEQERLLERERLLD 276
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQE-----EKIREQEEKRQEQEEKMWKQEEKIRE 616
E + ++E++R+Q+E++W+QE E++RE E + E +++Q + R
Sbjct: 277 EVEE-------LLEQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRS 329
Query: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
E++ + + + E++++E E+ +E + E
Sbjct: 330 GFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSE 364
Score = 102 bits (254), Expect = 1e-21
Identities = 77/286 (26%), Positives = 151/286 (52%), Gaps = 49/286 (17%)
Query: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE-EKIRKQEEKVWRQE 516
E I+ + +EEK+ E IH +++ R K+ Q E + + +
Sbjct: 110 ENINSLVRTSKEEKKHE----------IHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKV 159
Query: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
E+++++ +R++ E + RQ + E +M + RQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR---------------------RQE 198
Query: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
E++REQEE+ +REQEE+ EQEE++ +QEE++ EQEE++ EQ EK+ QE +
Sbjct: 199 ERLREQEER-------LREQEERLHEQEERLCEQEERLCEQEERLCEQ-EKLPGQERLLE 250
Query: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE-----EKI 691
E E++ ++E+ E++E++ E+E + E EE + ++E++R+Q++++ +QE E++
Sbjct: 251 EVEKLL--EQERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLRELERL 306
Query: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
RE E M++ E ++EQ + E++ + + + E+++ E E
Sbjct: 307 RELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELE 352
Score = 100 bits (249), Expect = 5e-21
Identities = 69/211 (32%), Positives = 121/211 (57%), Gaps = 19/211 (9%)
Query: 551 EKMHEQEKIWEEEKRQEQE--DKMWRQEEKIREQEEKVWRQEEKIREQE-EKRQEQEEKM 607
E ++ + +EEK+ E K+ R K++ Q + E + E+ Q++ +
Sbjct: 110 ENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHL 169
Query: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
K+ E + Q +Q + E + R QEE +EQEE++ EQEE++ EQEE++ EQE
Sbjct: 170 RKELESVGRQ---LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQE 226
Query: 668 ETMWRQEEKIREQEK-----KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722
E + QEE++ EQEK ++ E+ EK+ EQE QE++E++ E+E + E EE + +
Sbjct: 227 ERLCEQEERLCEQEKLPGQERLLEEVEKLLEQER-RQEEQERLLERERLLDEVEELL--E 283
Query: 723 EEKMRRQEEKMWEQEV-----RLRQQEEKMQ 748
+E++R+Q+E++W+QE RLR+ E ++
Sbjct: 284 QERLRQQDERLWQQETLRELERLRELERMLE 314
Score = 97.4 bits (241), Expect = 4e-20
Identities = 64/219 (29%), Positives = 124/219 (56%), Gaps = 19/219 (8%)
Query: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK---RQEQEAKMWRQEEKIREQEEKIRE 448
K+ +L+++ + K E ++ + E Q + QE ++ QEE++REQEE++ E
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHE 217
Query: 449 QEKKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK 507
QE+++ QEE++ EQE ++ E+EK QE + + EK+ EQE ++E++ E+E + +
Sbjct: 218 QEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDE 277
Query: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
EE + ++E++R+Q+E++W Q+E +RE E + RE E+M E WE Q
Sbjct: 278 VEELL---------EQERLRQQDERLW-QQETLRELERL-RELERMLELG--WEALYEQR 324
Query: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
E + +E + + + + E++++E E+ +E +
Sbjct: 325 AEPRSGFEE--LNNENKSTLQLEQQVKELEKSGGAEEPR 361
Score = 96.3 bits (238), Expect = 9e-20
Identities = 73/277 (26%), Positives = 141/277 (50%), Gaps = 16/277 (5%)
Query: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368
+Q+ E + QE + I + E + E+++ + + K++ Q
Sbjct: 84 LQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQ 143
Query: 369 --EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE-----KRQEEEKIRE 421
E + E + E++ E +ELE + + E + R++EE++RE
Sbjct: 144 TAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLRE 203
Query: 422 QEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
QE+R +EQE ++ QEE++ EQEE++ EQE+++ QE+ ++ + E EK EQE
Sbjct: 204 QEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQE 263
Query: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE-----EKIREQEEKIREQEEKMWR 535
++E++ E+E + + E++ EQ E++R+Q+E++W+QE E++RE E + E ++
Sbjct: 264 EQERLLERERLLDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYE 322
Query: 536 QEEKIREQEEMWREEEK--MHEQEKIWEEEKRQEQED 570
Q + R E E K + ++++ E EK E+
Sbjct: 323 QRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 359
Score = 59.7 bits (143), Expect = 1e-08
Identities = 37/134 (27%), Positives = 72/134 (53%), Gaps = 5/134 (3%)
Query: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE-EKMQEQEETMWRQEEKIRE 679
I + E I +E+++ +K+G K+ Q E + + + E++++
Sbjct: 105 ISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQD 164
Query: 680 QEKKIREQEEKIREQEEMMQEQEEKMW----EQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
+ +R++ E + Q + E + + QEE++ EQEE+++EQEE++ QEE++ E
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCE 224
Query: 736 QEVRLRQQEEKMQE 749
QE RL +QEE++ E
Sbjct: 225 QEERLCEQEERLCE 238
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 166 bits (420), Expect = 7e-41
Identities = 151/575 (26%), Positives = 287/575 (49%), Gaps = 57/575 (9%)
Query: 211 RNTITDEELKEKNAKLQ----EKLQLVESEKSEIQLNVKELKRKLERAK----------L 256
+N++ DEE K Q ++ +E + K L+ LER K L
Sbjct: 71 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 130
Query: 257 LLPQQQLQ---AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
LP +++Q AE + KE +S S + + ++EE E + Q+ + WR E
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND---WRDAE------ 181
Query: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
E +E +EK E+EEK + + E M+ EK + + + +M K ++ +E
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP--- 238
Query: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ-----EEEKIREQEKRQEQ 428
K+E+ R Q EK+ E +++ E E+ R + E+R+ +++KI ++ R E
Sbjct: 239 -KQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEA 297
Query: 429 EAKMWRQEEKIREQEEK--IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
E K QE + RE EE+ +RE+EK+ + ++I E+EK EE+++ +EE R E
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE--- 354
Query: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ--- 543
E++ I ++++ E+ ++ R +EE ++ K+ EQ+ + +E+K QE KI+ +
Sbjct: 355 ERQRIKEEEKRAAEERQRARAEEE----EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410
Query: 544 ---EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
E W E+K E + K+Q +E Q ++ + QE+K ++E+I++++ K+
Sbjct: 411 QKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 470
Query: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
++ ++ K ++ +++ Q + + K E + +E + Q
Sbjct: 471 DKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQV 530
Query: 661 EKMQEQEETMWRQEEKIREQEKKIRE-QEEKIREQEEMMQEQEE--KMWEQEEKMCEQEE 717
E + EE R+ E E+ +K+++ Q+E E EE+ +++EE K+ E+EE+ +QEE
Sbjct: 531 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE 590
Query: 718 ---KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
K++E+EEK RR +E++ + ++ +KM E
Sbjct: 591 ADRKLREEEEK-RRLKEEIERRRAEAAEKRQKMPE 624
Score = 158 bits (399), Expect = 2e-38
Identities = 106/479 (22%), Positives = 244/479 (50%), Gaps = 32/479 (6%)
Query: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
+++ E L +Q+ E+M + E+I ++ ++EE RE+ + R++ + +++EE +
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIA-YQRNDDDEEEAARERRRRARQERLRQKQEEESL 59
Query: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
+ +++ + EE E +++ E + +E + + L+E + Q+
Sbjct: 60 GQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK 119
Query: 405 KI--------REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
+ +R + + + +E++++ ++ +I E E + +K WR
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRD 179
Query: 457 EEKIHEQEKIREEEKRQE---------QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK 507
E+ +++K +EEE+ ++ Q E+ +E+ QEE K + + K
Sbjct: 180 AEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPK 239
Query: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
QEE+ + ++I E+ E +E+ + ++ +E RE K + +KI +E R E
Sbjct: 240 QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEE---RERIKAEQDKKIADERARIE 296
Query: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
E+K QE + RE EE+ E++RE+E++ E+ +++ ++E++ E+ ++I+E+E++
Sbjct: 297 AEEKAAAQERERREAEER-----ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 351
Query: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687
E+ ++I+E+E+ E+ ++ +E E++ K++EQ+ +E+K QE KI+
Sbjct: 352 AAEERQRIKEEEKRAAEERQRARAEE----EEKAKVEEQKRNKQLEEKKHAMQETKIK-- 405
Query: 688 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
EK+ ++ E E+K E + + +++ +E+ K++ + EK+ E + +++E K
Sbjct: 406 GEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIK 464
Score = 133 bits (335), Expect = 5e-31
Identities = 152/608 (25%), Positives = 285/608 (46%), Gaps = 55/608 (9%)
Query: 56 RQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGC--HSPEDEQKA 113
RQ + E+ Q+TD Q + + D + K T E E++
Sbjct: 51 RQKQEEESLGQVTD---QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERR 107
Query: 114 SHQHQEALRRELEAQ-VHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWK 172
+ QEAL R+ E T L+ +Q ++ K+ + E+R + ++
Sbjct: 108 QKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETET 167
Query: 173 FAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELK----EKNAKLQE 228
++ A + KK D+ EE +E+ R +I + +++ EK + QE
Sbjct: 168 VTKSYQKNDWRDAEENKKEDKEKEEEEEEKPK------RGSIGENQVEVMVEEKTTESQE 221
Query: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288
+ ++ + +I + + + E+ + + E D + ++ A+L+A+ E
Sbjct: 222 ETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDK--ERAEAERARLEAEERE- 278
Query: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
R+ +Q++K+ + +I E EEK QE + RE EE+ R +EE+ R EE KE
Sbjct: 279 ----RIKAEQDKKIADERARI-EAEEKAAAQERERREAEERERMREEEKRAAEERQRIKE 333
Query: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
E+ R EE KEE+ R EE KEE+ R EE + E+ E + K+ EQ++ ++
Sbjct: 334 EEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE--EEKAKVEEQKRNKQ 391
Query: 409 QEEKRQ--EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH-EQEK 465
EEK+ +E KI+ ++ Q+ E K W E+K +E + + +K+ + K+ ++EK
Sbjct: 392 LEEKKHAMQETKIKGEKVEQKIEGK-WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK 450
Query: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE---KIRKQEEKVWRQEEKIREQ 522
++E++ ++EE+ ++EKI + +E + + ++++ +++ Q + + K E
Sbjct: 451 LQEDKPTFKKEEI--KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTEN 508
Query: 523 -------EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE-----QED 570
+ +E + Q E + EE+ R + +E ++K+QE +E
Sbjct: 509 TFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEEL 568
Query: 571 KMWRQEE-KIREQEEKVWRQEE---KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626
K R+E K+ E+EE+ +QEE K+RE+EEKR+ +EE E + E EK Q+ E
Sbjct: 569 KKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEE----IERRRAEAAEKRQKMPE 624
Query: 627 KIREQEEK 634
++K
Sbjct: 625 DGLSDDKK 632
Score = 130 bits (327), Expect = 4e-30
Identities = 102/413 (24%), Positives = 203/413 (49%), Gaps = 53/413 (12%)
Query: 377 EKMRRQEEMMWEKEEKIR-ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435
+ R+ E+ +K E++R E E +++ E+E R+ + R++ RQ+QE + Q
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 436 ---------EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
+ + ++E K ++ +E + R EE+RQ+ R +E +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQK-----RLQEALE 116
Query: 487 EQEEI------------WRQKEKMHEQEEKIRKQEEKVWRQEE-KIREQEEKIREQEEKM 533
Q+E R+ + + E K+E+ RQE +I E E + ++
Sbjct: 117 RQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND 176
Query: 534 WRQ-EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
WR EE +E +E EEE+ ++ I E + E+K +E E V +
Sbjct: 177 WRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQE-----ETVVMSLKNG 231
Query: 593 IREQEEKRQEQE-----------EKMWKQEEKIREQEEKIQ---EQEEKIREQEEKIREQ 638
EE +QE+E EKM ++E+K R + E+ + E+ E+I+ +++K
Sbjct: 232 QISSEEPKQEEEREQGSDEISHHEKM-EEEDKERAEAERARLEAEERERIKAEQDKKIAD 290
Query: 639 EEMTQEQEEKMG--EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
E E EEK E+E + E+ E+M+E+E+ + ++I+E+EK+ E+ ++I+E+E+
Sbjct: 291 ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEK 350
Query: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
E+ +++ E+E++ E+ ++ + +EE+ + EE+ ++ +L +++ MQE
Sbjct: 351 RAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ--KRNKQLEEKKHAMQE 401
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 166 bits (419), Expect = 1e-40
Identities = 111/434 (25%), Positives = 238/434 (54%), Gaps = 28/434 (6%)
Query: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 376
Q ++ + E+ R++E + RR+ +RQ E +++ + RR+++ +++
Sbjct: 44 QAHKDADGDDRERNRQKERERRRE-----------KRQTERETDRKRERRREKDRHRKRD 92
Query: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
RQ + E+E + ++ E+E+ R++E +R+ E RE E+ ++++ R+
Sbjct: 93 RHRERQRDREKERERQTDRERDRQREKERNRQKERERETE---REGERGRDRQTDGQRER 149
Query: 437 EKIREQE-EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
E+ R+ E E+ R+ +++ RQ E+ ++E+ RE+ RQE+ E RQ EK ++ E+ ++
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKN-RQERRERERQREKENKTEDRHSER 208
Query: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKI-REQEEKMWRQEEKIREQE-EMWREEEKM 553
+ E+E + + E+ RQ ++ R+++ K RE+E++ R+ RE E + RE E+
Sbjct: 209 GRERERERETETETERK-RQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
Query: 554 HEQEKIWEEEKRQEQED-KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
++++ +++R+ Q D K R+ E+ RE E K RQ E+ RE+E R+ + E+ E
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER-----E 322
Query: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
+ RE+E + + + ++ +E+E K + Q EM +E+ + G + + E+E + + + +
Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA 382
Query: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
+E + RE+++ Q+E+ R+ E+ Q E ++E E++ + + E+ R +E++
Sbjct: 383 REREERERDRDRDRQKERERQTEKDRDGQRETEKQRER---EKDRESERGRERGREREKQ 439
Query: 733 MWEQEVRLRQQEEK 746
+ R RQ + +
Sbjct: 440 KGRERDRERQTDRQ 453
Score = 162 bits (411), Expect = 8e-40
Identities = 107/414 (25%), Positives = 225/414 (54%), Gaps = 24/414 (5%)
Query: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
N+Q+E + R+ EK Q E +++E R ++++ R+++ RQ + E+E + R+
Sbjct: 57 NRQKERE--RRREKRQTERETDRKRER--RREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 355 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 414
+ EKE +++ E E+E + R + ++E + + EK E++ RE++ +
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ---R 169
Query: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
+ E+ R++E+ +E+ + R+ E+ RE+E K ++ + R+ E+ E E E KRQ
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE-TETERKRQT 228
Query: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
E RQ + E+E+ ++ + E+ +++E + R ++ R Q+E+ R+ + K
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
Query: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
R+ E+ RE E R+ E+ E+E+ E +++E+E R+ E+ RE++ + R EK R
Sbjct: 289 RRTERDRETE---RKRERQRERERERERNRKRERE----RERERERERQRETERDREKER 341
Query: 595 EQEEKRQEQEEKMWKQE-------EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
E++ KRQ + ++ ++ + RE+E + + + RE+EE+ R+++ Q++ E
Sbjct: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
Query: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
+ E++ + EK +E+E+ R+ E+ RE+ ++ +Q+ + R++E Q
Sbjct: 402 RQTEKDRDGQRETEKQREREKD--RESERGRERGREREKQKGRERDRERQTDRQ 453
Score = 156 bits (394), Expect = 8e-38
Identities = 108/415 (26%), Positives = 227/415 (54%), Gaps = 27/415 (6%)
Query: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE---------QEEKIREQEEKMRRQEE 342
NR +++ + RQ E+ E + K + + EK R Q ++ +E+E + R+ +
Sbjct: 57 NRQKERERRREKRQTER--ETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE---EKIRELEEK 399
EKE +++ E E+E + R + ++E + +R E E++ E+ R+ E
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 400 MHEQEKIREQEEKRQEEEKIREQE-KRQEQEAKMWRQEEKIREQE---EKIREQEKKMWR 455
++ + + ++R+E E+ RE+E K +++ ++ R+ E+ RE E E+ R+ +++ R
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Q + E+EK E E+ E+E R +E+ E++ R +++ Q+E+ R+ + K R+
Sbjct: 235 QRKTEREREKQAERERASERETE-RDKERERERD---RDRDRDRRQKERERQTDRKRQRR 290
Query: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
E+ RE E K RE++ + R+ E+ R++E RE E+ E+++ E ++ +E+E K RQ
Sbjct: 291 TERDRETERK-RERQRERERERERNRKRERE-RERERERERQRETERDREKERERKRKRQ 348
Query: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
E RE+ + R+ + E+E +R+ + ++ +E + RE++ Q+E+ R Q EK
Sbjct: 349 TEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER-QTEKD 407
Query: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690
R+ + T++Q E+ ++E + E+ +E+E+ R+ ++ R+ +++ Q ++
Sbjct: 408 RDGQRETEKQREREKDRESE--RGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 152 bits (383), Expect = 1e-36
Identities = 99/390 (25%), Positives = 204/390 (52%), Gaps = 16/390 (4%)
Query: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQ-EKIREQEEKR-QEEEKIREQEKRQEQEAK 431
++E +++ E EK + RE + K + EK R ++ R +E ++ RE+E+ ++ + +
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 432 MWRQEEKIRE-QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
RQ EK R Q+E+ RE E++ R ++ + ++ RE ++ E+E + + + Q E
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE 550
RQKE+ E+ + R++ E+ +E K ++ + + E+ E + + + RE
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
++ + E+ E EK+ E+E R+ E+ +E+E + R ++ R Q+E+ ++ + K ++
Sbjct: 233 DRQRKTER--EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Query: 611 EEKIREQEEKIQEQEEKIREQE---------EKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
E+ RE E K + Q E+ RE+E E+ RE+E + + ++ E+E K Q E
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE 350
Query: 662 KMQEQEETMWRQ--EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
+E+ R+ + RE+E++ + RE+EE ++++ ++ E+ E++
Sbjct: 351 MDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDG 410
Query: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Q + EK R +E+ + R R +E + Q+
Sbjct: 411 QRETEKQREREKDRESERGRERGREREKQK 440
Score = 149 bits (376), Expect = 9e-36
Identities = 98/424 (23%), Positives = 233/424 (54%), Gaps = 23/424 (5%)
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
+Q + E ++ + + + + + E + + ++ +E + R++E+ ++ + + Q
Sbjct: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117
Query: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
EK R ++ +E+E + R+ E +++ +R+ E + E++ RQ + +++ +
Sbjct: 118 EKERNRQ---KERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 381 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 440
RQ+E E+E+ +E E+ ++EK + E++ E + RE+E+ E E + RQ ++ R
Sbjct: 175 RQKER--EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
+++ K E+E++ + E+ E+E R++E+ +E++ R ++ Q+E RQ ++ +
Sbjct: 233 DRQRKT-EREREKQAERERASERETERDKERERERD---RDRDRDRRQKERERQTDRKRQ 288
Query: 501 QE-EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
+ E+ R+ E K RQ E+ RE+E + + E R+ E+ RE++ RE E+ E+E+
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERE---RERERERERQ---RETERDREKER- 341
Query: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
E++++++ +M R+ + +E + + E+ RE+E RQ E+ ++ ++ R++++
Sbjct: 342 ---ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398
Query: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
+ + Q EK R+ + + +Q E +++E + G + + + EK + +E RQ ++
Sbjct: 399 ERERQTEKDRDGQRETEKQREREKDRESERGRERGR---EREKQKGRERDRERQTDRQAG 455
Query: 680 QEKK 683
+++K
Sbjct: 456 RQRK 459
Score = 140 bits (352), Expect = 6e-33
Identities = 113/448 (25%), Positives = 232/448 (51%), Gaps = 45/448 (10%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-HLGKEL 274
D + +E+N + +E+ + E ++E +E RK ER + E D H ++
Sbjct: 50 DGDDRERNRQ-KERERRREKRQTE-----RETDRKRERRR----------EKDRHRKRDR 93
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE---EKIQEQEEKIREQEEKIR 331
+ + + E + ++Q+E++ RQ+E+ +E E E+ ++++ + + E+ R
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
+ E++ RQ + +++ + RQ+E EK + RR+ E EKE K + + E
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 392 KIRELEEKMHEQEKIREQEEKRQEEEKI-REQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
+ RE E E E+ R+ + +R + K RE+EK+ E+E R+ E+ +K RE+E
Sbjct: 214 RERETET---ETERKRQTDRERDRQRKTEREREKQAERERASERETER-----DKERERE 265
Query: 451 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
+ R ++ ++ + + + KRQ + E R+ E+ E RQ+E+ E+E +++ E
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE-----RQRERERERERNRKRERE 320
Query: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
R+ E+ RE++ + EK +E K + Q EM RE + +E + E+ +E+E
Sbjct: 321 ---RERERERERQRETERDREK--ERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
Query: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE---EK 627
+ RQ + RE+ E R ++ R++E +RQ ++++ ++E + + + EK +E E E+
Sbjct: 376 ERDRQSAREREERE---RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER 432
Query: 628 IREQEEKIREQEEMTQEQEEKMGEQEEK 655
RE+E++ + + ++ + + G Q ++
Sbjct: 433 GREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 131 bits (330), Expect = 2e-30
Identities = 104/437 (23%), Positives = 220/437 (50%), Gaps = 45/437 (10%)
Query: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
++K+ +R E+ ER+ + R +++ K + +E+ + E E+ ++
Sbjct: 58 RQKERERRREKRQTERET---DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ-----AQVEENELWNRLNQQQEEK 301
+R+ ER + +++ + E + G++ Q+ + + A+ E +R Q+Q E+
Sbjct: 115 RQREKERNRQKERERETEREGER-GRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKI--REQEEKMRRQEEMMWEKEEKMRRQEEMMW 359
RQ+E+ +E + + + E+ RE+E K R E R+ E E E + +RQ +
Sbjct: 174 N-RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419
+++ K R+ E E+E R+ E +K E+E+ R+++ R+++E+
Sbjct: 233 DRQRKTEREREKQAERERASERETE------------RDKERERERDRDRDRDRRQKERE 280
Query: 420 REQEKRQEQEAKMWRQEEKIRE-QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478
R+ ++++++ + R+ E+ RE Q E+ RE+E+ R+ E+ E+E+ R+ E +++E+
Sbjct: 281 RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK- 339
Query: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE 538
+E K Q E+ R++ + +E R Q E+ RE+E + RQ
Sbjct: 340 -ERERKRKRQTEMDRERNRQTGREG----------------RRQAERERERERERDRQSA 382
Query: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE--EKVWRQEEKIREQ 596
+ RE+ E R+ ++ E+E+ E+++ ++E + R+ EK RE E + R+ EK + +
Sbjct: 383 REREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR 442
Query: 597 EEKRQEQEEKMWKQEEK 613
E R+ Q ++ ++ K
Sbjct: 443 ERDRERQTDRQAGRQRK 459
Score = 126 bits (317), Expect = 6e-29
Identities = 89/318 (27%), Positives = 181/318 (56%), Gaps = 17/318 (5%)
Query: 435 QEEKIREQEEKIREQEKKMWRQEEKIH-EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493
Q K + +++ R ++K+ R+ EK E+E R+ E+R+E++ +++ H + + R
Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR--HRERQRDR 101
Query: 494 QKEKMHEQE-EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
+KE+ + + E+ R++E++ RQ+E+ RE E RE E RQ + RE+E R+ EK
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETE---REGERGRDRQTDGQRERERQ-RDAEK 157
Query: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
E++ E +++ E+ RQ+E+ RE+ + R+ E+ RE+E K +++ + ++ E
Sbjct: 158 ERERQTDRERQRQTERN----RQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 613 KIREQEEKIQEQEEKIREQE-EKIREQEEMTQEQEEKMGEQE-EKMCEQEEKMQEQEETM 670
+ RE E + + + + RE++ ++ E+E Q + E+ E+E E+ E+E + +
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
RQ+E+ R+ ++K + + E+ RE E + Q E+ E+E + E+ +E+E + +R+
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 731 EKMWEQEVRLRQQEEKMQ 748
E+ E+E R+++ K Q
Sbjct: 334 ERDREKE---RERKRKRQ 348
Score = 116 bits (290), Expect = 9e-26
Identities = 97/396 (24%), Positives = 192/396 (48%), Gaps = 40/396 (10%)
Query: 186 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 245
T +K+ R ++ ++RD +R D E + + +E+ + E E++ + +
Sbjct: 75 TDRKRERRREKDRHRKRDR-----HRERQRDREKERERQTDRERDRQREKERNRQKERER 129
Query: 246 ELKRKLERAKLLLP--QQQLQAEADHLGKELQSVSAKLQAQVEENELWNR---LNQQQEE 300
E +R+ ER + Q++ + + D + + + Q Q E N R N+Q+
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 301 KMWRQEEKIQEWEEKIQEQ-EEKIREQE-----------EKIREQEEKMRRQEEMMWEKE 348
+ RQ EK + E++ E+ E+ RE+E ++ R+++ K R+ E E+E
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
Query: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
R+ E E+E + R + ++E+ R+ + + E+ RE E K Q +
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE---------EKIREQEKKMWRQEEK 459
+ E+ ++ E+ RE+E+ +E++ + R EK RE++ E+ R+ ++ RQ E+
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369
Query: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
E+E+ R+ + +E+EE R ++ Q+E RQ EK + + + KQ E+ EK
Sbjct: 370 ERERERERDRQSAREREERERDRDR-DRQKERERQTEKDRDGQRETEKQRER-----EKD 423
Query: 520 REQE---EKIREQEEKMWRQEEKIREQEEMWREEEK 552
RE E E+ RE+E++ R+ ++ R+ + + K
Sbjct: 424 RESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 100 bits (250), Expect = 4e-21
Identities = 100/420 (23%), Positives = 199/420 (47%), Gaps = 26/420 (6%)
Query: 84 DTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALR-RELEAQVHTIRILTCQKTEL 142
+ ++++ T ET +D + +H+E R RE E + T R Q+ E
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR-EK 119
Query: 143 QMALYYSQHAVKQLEGE-ARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE 201
+ + + EGE RD R D + E E+ A ++++ DR + T+
Sbjct: 120 ERNRQKERERETEREGERGRD---RQTDGQR---ERERQRDAEKERERQTDRERQRQTER 173
Query: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
E +N E +E+ + + K + SE+ + +E + + ER + ++
Sbjct: 174 NRQKEREREKNRQERRE-RERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE 321
Q + + +E + + + +A E E ++++E + R ++ + +E+ ++ +
Sbjct: 233 DRQRKTE---REREKQAERERASERETER----DKERERERDRDRDRDRRQKERERQTDR 285
Query: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE--KM 379
K + + E+ RE E K RQ E E+E +R+ E E+E + +R+ E EKE K
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
Query: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE--EEKIREQEKRQEQEAKMWRQEE 437
+RQ EM E+ + + E+E+ RE+E RQ E + RE+++ ++++ + RQ E
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE 405
Query: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
K R+ + RE EK+ R+ EK E E+ RE + +E+++ ++ + + RQ+++
Sbjct: 406 KDRDGQ---RETEKQ--REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 67.8 bits (164), Expect = 4e-11
Identities = 44/193 (22%), Positives = 100/193 (51%), Gaps = 14/193 (7%)
Query: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKI-REQEEKRQEQEEK-------MWKQEEKIREQ 617
Q +D E+ R++E + R++ + RE + KR+ + EK ++ ++ RE+
Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK 103
Query: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE-QEEKMQEQEETMWRQEEK 676
E + Q E+ R++E++ Q+E +E E + ++ + Q E+ ++++ R+ +
Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
Query: 677 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
RE++++ +K RE+E+ QE+ E+ E+ E+E K +++ + R+ E+ E
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRER-----ERQREKENKTEDRHSERGRERERERET 218
Query: 737 EVRLRQQEEKMQE 749
E ++ + +E
Sbjct: 219 ETETERKRQTDRE 231
Score = 54.7 bits (130), Expect = 3e-07
Identities = 32/135 (23%), Positives = 70/135 (51%), Gaps = 3/135 (2%)
Query: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
++E Q++ E+ RE+ + RE + + + EK ++ + ++ +E+E E
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 676 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
+ R++EK+ Q+E+ RE E +E E Q + E+E + ++E+ R+ + +
Sbjct: 113 RDRQREKERNRQKERERETE---REGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169
Query: 736 QEVRLRQQEEKMQEH 750
Q R RQ+E + +++
Sbjct: 170 QTERNRQKEREREKN 184
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 151 bits (381), Expect = 2e-36
Identities = 149/687 (21%), Positives = 329/687 (47%), Gaps = 67/687 (9%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIR-ILTCQKTELQMALYYSQHAVKQLEGEARDLISR 166
E EQK + Q ++ RELE T R +L Q EL+ ++ G+ +DL +
Sbjct: 1498 EREQKLTVQREQI--RELEKDRETQRNVLEHQLLELEK----KDQMIESQRGQVQDLKKQ 1551
Query: 167 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 226
L A ELE+ + Q+K I+EL +R+ + L T+ +L+E++ +L
Sbjct: 1552 LVTLECLALELEENHHKMECQQK----LIKELEGQRETQRVALTHLTL---DLEERSQEL 1604
Query: 227 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQV 285
Q + + +S + +EL+ + + K Q ++LQ + +HL ++L+ +L Q
Sbjct: 1605 QAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQK 1664
Query: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK--------- 336
E ++ L Q+ + EE +++ + ++E+ ++ Q + ++E+ E+
Sbjct: 1665 ERIQV---LEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQR 1721
Query: 337 --MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
+ + ++ +KE+++ Q+E + E +E + E+ + K+ ++ ++E++I
Sbjct: 1722 GSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIV 1781
Query: 395 ELEEKMHE---QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
L++++ E Q +++EQ + Q +E R +R ++ + +++++ + QEE+++E+
Sbjct: 1782 VLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841
Query: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH-EQEEIWRQKEKMHEQEEKIRKQEE 510
+ E+ H K R E + +E+ R EE++ E + +E + + + R+QE+
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEK 1901
Query: 511 KVWRQEEKIREQEE--------------------KIREQEEKMWRQE-EKIREQEEMWRE 549
+ +++ EQ + K R+QE + R E + R QEE R
Sbjct: 1902 ALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARA 1961
Query: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
+ ++ Q +E + Q E R E + + + ++ EE +
Sbjct: 1962 RAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRI 2021
Query: 610 QEEKIREQE----EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ-EEKMCEQEEKM- 663
QE +I++Q+ E +Q+ ++ + +++E++R Q+E Q E+ + ++ +E M ++++ +
Sbjct: 2022 QEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLG 2081
Query: 664 -QEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK---MCEQEEKM 719
+ +EE + + +RE + + ++E++I E E Q + K M EQ K+
Sbjct: 2082 QEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKL 2141
Query: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEK 746
E +++R+ E++ + LRQ E +
Sbjct: 2142 DSLEPRLQRELERL---QAALRQTEAR 2165
Score = 150 bits (379), Expect = 4e-36
Identities = 153/711 (21%), Positives = 353/711 (49%), Gaps = 101/711 (14%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+E + + L ++ E Q + +L+ + + Q +++LE + R ++ L
Sbjct: 1434 EEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELE-KCRSVLEHL 1492
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ + E EQ L+ Q I EL K+R E RN + + L+ L+
Sbjct: 1493 PMAVQ---EREQKLTVQREQ-------IRELEKDR-----ETQRNVLEHQLLE-----LE 1532
Query: 228 EKLQLVESEKSEIQ-------------LNVKELKRKLERAKLLLPQQQLQAEAD-----H 269
+K Q++ES++ ++Q L ++E K+E + L+ + + Q E H
Sbjct: 1533 KKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTH 1592
Query: 270 LGKELQSVSAKLQAQVEE-------NELWNRLNQQQEEKMWRQEEKIQEWEEK------- 315
L +L+ S +LQAQ + + + R Q++++++ Q E+I+E + +
Sbjct: 1593 LTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQD 1652
Query: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 375
++ +++++ Q+E+I+ E++ RQ +++ EE + + + + E+ ++ Q ++M E+
Sbjct: 1653 LERRDQELMLQKERIQVLEDQRTRQTKIL---EEDLEQIKLSLRERGRELTTQRQLMQER 1709
Query: 376 EEK-----------MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE--EEKIREQ 422
E+ + + ++ +KE+++ +E +HE +++++Q E++ + K+ E
Sbjct: 1710 AEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGET 1769
Query: 423 E----KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478
+R+++ + +Q ++ REQ E + + + ++ Q E +QEQ++
Sbjct: 1770 SLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQA 1829
Query: 479 WRQEEKIHEQEEIWRQK-EKMH----EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKM 533
QEE++ E+ + + E+ H E+ +++ +E+ R EE++ + +++ EE +
Sbjct: 1830 QGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVL 1889
Query: 534 WRQEEKIREQEE-MWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI---REQEEKVWRQ 589
+ REQE+ + +++ EQ + E E R Q+ W Q + + R+QE + R
Sbjct: 1890 GDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDS--WLQAQAVLKERDQELEALRA 1947
Query: 590 E-EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648
E + R QEE + + E + +E + + +Q +E+ + EQ E R E T +
Sbjct: 1948 ESQSSRHQEEAARARAEAL---QEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQAS 2004
Query: 649 MG-------EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
+ + EE + QE ++Q+Q+ R +E +++ ++ + +++E++R Q+E Q
Sbjct: 2005 LDACQAHSRQLEEALRIQEGEIQDQD---LRYQEDVQQLQQALAQRDEELRHQQEREQLL 2061
Query: 702 EEKMWEQ-EEKMCEQEEKM--QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
E+ + ++ +E M ++++ + + +EE++R + + E ++ L Q+E+++ E
Sbjct: 2062 EKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILE 2112
Score = 147 bits (371), Expect = 4e-35
Identities = 159/740 (21%), Positives = 344/740 (46%), Gaps = 101/740 (13%)
Query: 105 HSPEDEQKASHQHQEALRRELEAQVHT----IRILTCQK-------TELQMALYYSQHAV 153
H E + +AS QEA +L+ ++ + + L ++ + Q+A YS A+
Sbjct: 1132 HITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYS--AL 1189
Query: 154 KQLEG---EARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSL--- 207
+Q G E+R +S DS LE + + K+ + L+ E A +L
Sbjct: 1190 QQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGP-LLTALSAEAVASALHKL 1248
Query: 208 --ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL-----ERAKLLLPQ 260
+L++ T + L+++ KL+E+L E+EKS++ +++L+R+L E++K Q
Sbjct: 1249 HQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQ 1308
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
L++E EL A LQ+++ EL Q + E + +E + E +Q
Sbjct: 1309 NSLESEL----MELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAV 1364
Query: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
+ R Q EE +R + K E++ + E +E+ + +E +
Sbjct: 1365 VEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLA 1424
Query: 381 RQEEMMWEKEEKIRELEEKMHEQEKIREQEE-----------KRQEE-----EKIREQEK 424
+ + E+EE++ L ++ E EK RE ++ KR +E E+I+E EK
Sbjct: 1425 LLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEK 1484
Query: 425 R-----------QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 473
QE+E K+ Q E+IRE E+ Q + Q ++ +++++ E ++ Q
Sbjct: 1485 CRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQ 1544
Query: 474 EQE-------------EMWRQEEKIHEQEEIWRQKEKMHEQEE--------KIRKQEEKV 512
Q+ E+ K+ Q+++ ++ E E + + ++ +++
Sbjct: 1545 VQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQEL 1604
Query: 513 WRQEEKIREQEE---------KIREQEEKMWRQE-EKIREQEEMWREEEKMHEQEKIWEE 562
Q +I + E + R+QE K R++ E+++ Q+E ++ + +QE + ++
Sbjct: 1605 QAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQK 1664
Query: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQ-EEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
E+ Q ED+ RQ + + E E++ E+ RE +RQ +E+ + + + Q +
Sbjct: 1665 ERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSL 1724
Query: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
+ + +R++E+++ Q+E E +E + E+++ K+ E + ++E++I +
Sbjct: 1725 EHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQ 1784
Query: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ----- 736
++++E E+ +E+ +Q Q ++ + ++ E +Q+++++ + QEE++ E+
Sbjct: 1785 QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQ 1844
Query: 737 ------EVRLRQQEEKMQEH 750
+ L+++ ++Q+H
Sbjct: 1845 GALEQAHMTLKERHGELQDH 1864
Score = 144 bits (364), Expect = 2e-34
Identities = 136/651 (20%), Positives = 318/651 (48%), Gaps = 59/651 (9%)
Query: 119 EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELE 178
E ++E Q I+ L Q+ ++AL + +++ E + S++HD + L
Sbjct: 1563 EENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLA 1622
Query: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ-------EKLQ 231
+ L + K IEEL ++++ L+ +L R D+EL + ++Q + +
Sbjct: 1623 RELQERDQEVKSQREQIEELQRQKEHLTQDLERR---DQELMLQKERIQVLEDQRTRQTK 1679
Query: 232 LVESEKSEIQLNVKELKRKLERAKLLL---------PQQQLQAEADHLGKELQSVSAKLQ 282
++E + +I+L+++E R+L + L+ P + + +H+ L+ +++
Sbjct: 1680 ILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVE 1739
Query: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
Q E L Q E+++ K+ E + ++E++I +++++E E+ +E+
Sbjct: 1740 CQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQ 1799
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 402
+ + ++ +R + ++++++ E + +++++ + QEE + EK + ++ E+ H
Sbjct: 1800 SLQSQLDEAQRA---LAQRDQEL----EALQQEQQQAQGQEERVKEKADALQGALEQAHM 1852
Query: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 462
K R E + +E+ R +E+ + ++ EE + + + REQEK + +++ E
Sbjct: 1853 TLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAE 1912
Query: 463 QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ 522
Q + E E R Q+ W Q + + ++ + ++ E + + + R QEE + E +
Sbjct: 1913 QAQEHEVETRALQDS-WLQAQAVLKERD--QELEALRAESQSSRHQEEAARARAEAL--- 1966
Query: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEK----MHEQEKIWEEEKRQEQEDKMWRQEEK 578
+E + + + +E+ + EQ E+ R E + + RQ EE
Sbjct: 1967 QEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQ--------LEEA 2018
Query: 579 IREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI--REQEEKIR 636
+R QE ++ Q++ +R QE+ +Q Q + + +++E++R Q+E+ Q E+ + R QE I+
Sbjct: 2019 LRIQEGEI--QDQDLRYQEDVQQLQ-QALAQRDEELRHQQEREQLLEKSLAQRVQENMIQ 2075
Query: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
E++ + QE+E EE++ + ++E + T+ ++E++I E +RE +++ +
Sbjct: 2076 EKQNLGQERE------EEEIRGLHQSVRELQLTLAQKEQEILE----LRETQQRNNLEAL 2125
Query: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
+ M EQ K+ E ++Q + E+++ + +E+ R++ + +
Sbjct: 2126 PHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDL 2176
Score = 144 bits (363), Expect = 3e-34
Identities = 162/681 (23%), Positives = 323/681 (47%), Gaps = 88/681 (12%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E +Q S LR LE+ +L ++TE+ AL ++ ++ +L L + +
Sbjct: 532 EAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEV 591
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKE--------------RDALSLELYRNT 213
D A +L A+A K ++ + +L +E R+AL ++L
Sbjct: 592 ADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAE 651
Query: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
E L EKN L+ +LQ E +E+Q ++++++ + E + L + + Q EA
Sbjct: 652 KRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEA------ 705
Query: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE-KIRE 332
Q+E+ QE K RQEE + +QE+E +RE+ ++R
Sbjct: 706 -------ATTQLEQ--------LHQEAK--RQEEVLAR---AVQEKEALVREKAALEVRL 745
Query: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Q + RQ+ + E+ + + +E++ + ++Q ++ + ++ Q + + + +E
Sbjct: 746 QAVERDRQD--LAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEV 803
Query: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
I+ E + + E E+ + QE + Q + EQE K +++K ++E + +EK
Sbjct: 804 IQG-EVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK- 861
Query: 453 MWRQEEKIHEQE--KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE------K 504
W +E H+QE K E +R++ E R +E+ E E I Q+E+ Q E +
Sbjct: 862 -WEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQ 920
Query: 505 IRKQEEKVWRQEEKIREQEEKI-REQEEKMWRQE---EKIREQEEMWREEEKMHEQEKIW 560
+ ++E+V E ++ Q+E Q+ + RQ+ +K++EQE + ++ E ++
Sbjct: 921 LETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQREL 980
Query: 561 EEEKRQEQEDKMWRQEEKIREQEEKV--WRQEEKIREQ------EEKRQEQEEKMWKQEE 612
+E RQ ++D QEE ++K+ +Q E ++ Q ++ EQ
Sbjct: 981 KEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQ--------- 1031
Query: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
E +EK++E +E R Q+E RE+ +T EK EQ + ++ + +++QE + R
Sbjct: 1032 ---EVQEKLRETQEYNRIQKELEREKASLTLSLMEK--EQRLLVLQEADSIRQQELSALR 1086
Query: 673 QE-EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR---- 727
Q+ ++ + ++K++ Q E +R++ ++E+E QE ++ E+ E E+++R
Sbjct: 1087 QDMQEAQGEQKELSAQMELLRQE---VKEKEADFLAQEAQLLEELEASHITEQQLRASLW 1143
Query: 728 RQEEKMWEQEVRLRQQEEKMQ 748
QE K + ++RLR E +++
Sbjct: 1144 AQEAKAAQLQLRLRSTESQLE 1164
Score = 134 bits (337), Expect = 3e-31
Identities = 156/748 (20%), Positives = 345/748 (46%), Gaps = 87/748 (11%)
Query: 52 SKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQ 111
+++ + ++ + +E+LTD + + V T D +++ ++ ++ G +S E E
Sbjct: 1258 TRDVLRDQVQKLEERLTDTEAEKS-QVHTELQDLQRQ-LSQNQEEKSKWEGKQNSLESEL 1315
Query: 112 KASHQH----QEALRR----ELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDL 163
H+ Q LRR +EAQ +L K L + + Q AV + +A
Sbjct: 1316 MELHETMASLQSRLRRAELQRMEAQGER-ELLQAAKENLTAQVEHLQAAVVEARAQA--- 1371
Query: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
AG LE+ L + K + +E + AL + + L+E
Sbjct: 1372 --------SAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENL 1423
Query: 224 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA 283
A L + L E E ++ ++EL+++ E K L L + + +LQ Q
Sbjct: 1424 ALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQ------QE 1477
Query: 284 QVEENELWNRLN-------QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Q++E E + Q++E+K+ Q E+I+E E+ + Q + Q ++ ++++
Sbjct: 1478 QIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQM 1537
Query: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEE---KMRRQEEMMWEKEEKMRRQE----EMMWEK 389
+ Q + + ++++ E + E EE KM Q++++ E E + Q + +
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 390 EEKIRELE---EKMHEQEK-----IREQEEKRQEEEKIREQ-EKRQEQEAKMW----RQE 436
EE+ +EL+ ++H+ E RE +E+ QE + REQ E+ Q Q+ + R++
Sbjct: 1598 EERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRD 1657
Query: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
+++ Q+E+I+ E + RQ + + E + + R+ E+ Q + + E+ E +
Sbjct: 1658 QELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPS 1717
Query: 497 K------------MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQE 544
K + ++E+++ Q+E + +++E ++++ +Q + + R K+ E
Sbjct: 1718 KAQRGSLEHMKLILRDKEKEVECQQEHI----HELQELKDQLEQQLQGLHR---KVGETS 1770
Query: 545 EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE 604
+ + EQE + +++ QE ++ +E+ ++ Q ++ R + ++ E Q+++
Sbjct: 1771 LLLSQ----REQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQ 1826
Query: 605 EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
++ QEE+++E+ + +Q + + ++E+ Q+ +E+ EE++ + ++Q
Sbjct: 1827 QQAQGQEERVKEKADALQ---GALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1883
Query: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE- 723
EE + + REQEK + +++ EQ QE E + ++ + + ++E++
Sbjct: 1884 ALEEVLGDLRAESREQEKALLALQQQCAEQ---AQEHEVETRALQDSWLQAQAVLKERDQ 1940
Query: 724 --EKMRRQEEKMWEQEVRLRQQEEKMQE 749
E +R + + QE R + E +QE
Sbjct: 1941 ELEALRAESQSSRHQEEAARARAEALQE 1968
Score = 115 bits (289), Expect = 1e-25
Identities = 159/801 (19%), Positives = 335/801 (41%), Gaps = 128/801 (15%)
Query: 54 ETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKA 113
ET ++L E + L+ + + S+ D + + G N Q +
Sbjct: 317 ETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIA-------------QGS 363
Query: 114 SHQHQEALRRELEAQVH---TIRILTCQKTELQMALYYSQHAVKQLEG--EARDLISRLH 168
H++ L + +Q + LT ++ L Q +QL G EA +L+ + H
Sbjct: 364 GHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQH 423
Query: 169 DSWKFAGE-LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK----- 222
D W+ G+ L Q L + ++ +L E D+LS E EEL+++
Sbjct: 424 DQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLE 483
Query: 223 ---------NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
N +LQ + + +K E Q + R+ ER + +L L+A+ E
Sbjct: 484 QEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEML--MGLEAKQSESLSE 541
Query: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK------------------ 315
L ++ L++ E EL + + + R E+ I E
Sbjct: 542 LITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKL 601
Query: 316 -------------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK- 361
+ +Q ++ E+ + + + E + + + ++ E +WEK
Sbjct: 602 SALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKN 661
Query: 362 ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR------EQEEK 412
E ++++ EE E + +R +E EKEE ++L E H+QE QE K
Sbjct: 662 THLEAQLQKAEEAGAELQADLRDIQE---EKEEIQKKLSESRHQQEAATTQLEQLHQEAK 718
Query: 413 RQEE---EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH-------E 462
RQEE ++E+E ++A + + + + + + EQ + + +E + +
Sbjct: 719 RQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQ 778
Query: 463 QEKIREEEKRQEQEEMWR--QEEKIHEQE------EIWRQKEKMHEQEEKIRKQEEKVWR 514
Q + E K Q + ++ Q +++ + E E+ ++ + ++ + +Q + +
Sbjct: 779 QNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQ 838
Query: 515 QEEKIREQEEKIREQE----------EKMWRQEEKIREQEEMWRE----EEKMHEQEKIW 560
+ + EQ++ E+E E+ W Q+E + E + RE E ++ EQ+
Sbjct: 839 EGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEM 898
Query: 561 EEEKRQEQEDKMWRQ----EEKIREQEEKVWRQEEKIREQEE----------KRQEQEEK 606
E + Q +E++ + + ++ ++E+V E ++ Q+E RQ+ + +
Sbjct: 899 EAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQ 958
Query: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
K++E + ++QE + +++E + R+ QE+ + + + + +Q E ++ Q
Sbjct: 959 KLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQ 1018
Query: 667 EETMWRQEEKI-REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
+ + +E ++K+RE +E R Q+E+ +E+ EK EQ + ++ +
Sbjct: 1019 LVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEK--EQRLLVLQEADS 1076
Query: 726 MRRQEEKMWEQEVRLRQQEEK 746
+R+QE Q+++ Q E+K
Sbjct: 1077 IRQQELSALRQDMQEAQGEQK 1097
Score = 113 bits (283), Expect = 6e-25
Identities = 143/725 (19%), Positives = 314/725 (43%), Gaps = 112/725 (15%)
Query: 112 KASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHA-------VKQLEGEAR--- 161
+A Q E EL+A + I+ +K E+Q L S+H ++QL EA+
Sbjct: 665 EAQLQKAEEAGAELQADLRDIQE---EKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQE 721
Query: 162 DLISR-LHDSWKFAGE---LEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
++++R + + E LE L AV ++ ++ L+ ++ L L+ +
Sbjct: 722 EVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS 781
Query: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
++ +L+ ++Q V K IQ V+ LK +L+ + Q++ A E +
Sbjct: 782 VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGK 841
Query: 278 SAKLQAQVEENELWNRLNQQQE-EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
+A Q + + N+L ++ E E+ W Q QE + ++ E + E E +++EQ+ +
Sbjct: 842 TALEQQKAAHEKEVNQLREKWEKERSWHQ----QELAKALESLEREKMELEMRLKEQQTE 897
Query: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
M E + ++EE+ + E + + + + ++E + E ++ Q+E+ + +++ L
Sbjct: 898 M---EAIQAQREEERTQAESALCQMQ--LETEKERVSLLETLLQTQKELA-DASQQLERL 951
Query: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-EKIREQEEKIREQEKKMWR 455
+ M Q K++EQE + +++E ++ ++ A+ R + ++E+ + + + + +
Sbjct: 952 RQDMKVQ-KLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQK 1010
Query: 456 QEEKIHEQEKIREEEKR---QEQEEMWRQEEKIHE-QEEIWRQKEKMH------------ 499
Q E + Q +++ +R QE +E R+ ++ + Q+E+ R+K +
Sbjct: 1011 QVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLV 1070
Query: 500 -EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
++ + IR+QE RQ+ + + E+K + ++ RQE K +E + + +E + + E E
Sbjct: 1071 LQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEA 1130
Query: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR----EQEEKRQEQEE--------- 605
E Q+ +W QE K + + ++ E ++ EQ+ Q Q +
Sbjct: 1131 SHITE--QQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSA 1188
Query: 606 -----------------------KMWKQE---------------------EKIREQEEKI 621
+W E E + K+
Sbjct: 1189 LQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKL 1248
Query: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
+ K ++ + +R+Q Q+ EE++ + E + + ++Q+ + + + +E+ + E
Sbjct: 1249 HQDLWKTQQTRDVLRDQ---VQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWE 1305
Query: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE---QEEKMQEQEEKMRRQEEKMWEQEV 738
K E ++ E E M + ++ E + E + E +Q +E + Q E + V
Sbjct: 1306 GKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVV 1365
Query: 739 RLRQQ 743
R Q
Sbjct: 1366 EARAQ 1370
Score = 110 bits (274), Expect = 6e-24
Identities = 143/700 (20%), Positives = 314/700 (44%), Gaps = 97/700 (13%)
Query: 138 QKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA--------LSAVATQKK 189
+ +L + L +Q K+ +++LI K G+LE+A LSA+ TQ +
Sbjct: 242 EPAQLLLLLAKTQELEKEAHERSQELIQL-----KSQGDLEKAELQDRVTELSALLTQSQ 296
Query: 190 KADRYIEELTKE-RDALS-LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE- 246
K + E++ K R+ + LE + + E +EKL L + K Q+ V+E
Sbjct: 297 KQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEG 356
Query: 247 --------LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE--------NEL 290
+ LE + Q Q +AD ++SV + + V++ E
Sbjct: 357 DNIAQGSGHENSLELDSSIFSQFDYQ-DADKALTLVRSVLTRRRQAVQDLRQQLAGCQEA 415
Query: 291 WNRLNQQQEEKMWRQEEK-IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349
N L QQ ++ W +E K +++ +K+ + + + Q ++ + + + ++ E++ + E
Sbjct: 416 VNLLQQQHDQ--WEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKARE 473
Query: 350 KMRRQEEMMWEKEEKMRR-------------------QEEMMWEKEEKMRRQEEMMWEKE 390
++R+Q E++ ++ ++RR QEE+ E+ R QE +M +
Sbjct: 474 ELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEA 533
Query: 391 EKIRELEEKMHEQEKIR----EQEEKRQEEEKIREQEKRQEQE-AKMWRQEEKIREQEEK 445
++ L E + +E + E E RQE+ ++ R EQ A++ E ++ +
Sbjct: 534 KQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVAD 593
Query: 446 IREQEKKMWRQEEKIH------EQEKIREEEKRQ------EQEEMWRQEEKIHEQEEIWR 493
+R K+ E + Q+ ++ EE+ Q E E R ++ + E +
Sbjct: 594 LRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQV-DLAEAEK 652
Query: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE-EK 552
++E + E+ + Q +K +++ I+E++E++ ++ + R Q+E + E+
Sbjct: 653 RREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQ 712
Query: 553 MHEQEKIWEE--EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
+H++ K EE + ++++ + R++ + + + V R + + EQ + +E +
Sbjct: 713 LHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESS 772
Query: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ----------EQEEKMGEQEEKMCEQE 660
+ ++Q I+ + ++ Q + + + +E+ Q + E EQE ++
Sbjct: 773 LFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQ 832
Query: 661 EKMQEQE-ETMWRQEEKIREQE-KKIREQEEKIRE--QEEM---MQEQEEKMWEQEEKMC 713
EQE +T Q++ E+E ++RE+ EK R Q+E+ ++ E + E E ++
Sbjct: 833 LAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLK 892
Query: 714 EQEEKM----QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
EQ+ +M ++EE+ + E + + ++ ++ + E
Sbjct: 893 EQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLE 932
Score = 107 bits (268), Expect = 3e-23
Identities = 145/710 (20%), Positives = 305/710 (42%), Gaps = 130/710 (18%)
Query: 117 HQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDL------ISRLHDS 170
H L REL+ + ++ Q ELQ +H + LE ++L I L D
Sbjct: 1617 HSTVLARELQERDQEVKSQREQIEELQRQ---KEHLTQDLERRDQELMLQKERIQVLEDQ 1673
Query: 171 -WKFAGELEQALSAVATQKKKADRYIEELTKERDAL----------------SLELYRNT 213
+ LE+ L + ++ R ELT +R + SLE +
Sbjct: 1674 RTRQTKILEEDLEQIKLSLRERGR---ELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLI 1730
Query: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
+ D+E KE + QE + ++ K +++ ++ L RK+ LLL Q++ + L ++
Sbjct: 1731 LRDKE-KEVECQ-QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVV--LQQQ 1786
Query: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE--KIQEWEEKIQEQEEKIREQEEKIR 331
LQ A+ Q +++E L ++L++ Q R +E +Q+ +++ Q QEE+++E+ + ++
Sbjct: 1787 LQE--AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQ 1844
Query: 332 EQEEK----MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
E+ ++ + + + +E+ RR EE + + +++ EE++ + + R QE+ +
Sbjct: 1845 GALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALL 1904
Query: 388 EKEEKIRE----------------------LEEKMHEQEKIR-EQEEKRQEEEKIRE--- 421
+++ E L+E+ E E +R E + R +EE R
Sbjct: 1905 ALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAE 1964
Query: 422 --QEKRQEQEAKMWRQEEKIREQEE---------------------KIREQEKKMWRQEE 458
QE + A + +E+ + EQ E R+ E+ + QE
Sbjct: 1965 ALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEG 2024
Query: 459 KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK---MHEQEEKIR-KQEEKVWR 514
+I +Q+ +E+ +Q Q+ + +++E++ Q+E + EK QE I+ KQ R
Sbjct: 2025 EIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQER 2084
Query: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
+EE+IR + +RE + + ++E++I E RE ++ + E + K E++ +
Sbjct: 2085 EEEEIRGLHQSVRELQLTLAQKEQEILEL----RETQQRNNLEALPHSHKTSPMEEQSLK 2140
Query: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR----- 629
+ + ++ R + +R+ E + E EK + + + + +E
Sbjct: 2141 LDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQAS 2200
Query: 630 -----EQEEKIREQEEMTQEQEEK----------------MGEQ-----EEKMCEQEEKM 663
++++++++ E+T+ EK GEQ E E E
Sbjct: 2201 VLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSP 2260
Query: 664 QEQEETMWRQE-EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 712
E+ WRQ E +++ ++ +++ ++ E++ + K+
Sbjct: 2261 DGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKL 2310
Score = 68.2 bits (165), Expect = 3e-11
Identities = 109/567 (19%), Positives = 245/567 (43%), Gaps = 51/567 (8%)
Query: 197 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 256
+L E L+L+ +++ E A KL+ E Q L RKL+ AK+
Sbjct: 17 QLVLEEQVLALQ--------QQMAENQAASWRKLK----NSQEAQQRQATLVRKLQ-AKV 63
Query: 257 LLPQQQLQAEADHLGKELQSVSAKLQAQ---VEENELWNRLNQQQEEKMWRQEEKIQEWE 313
L Q ++ L K L++ + + VEE L L + +EE+ ++ E + E
Sbjct: 64 L----QYRSWCQELEKRLEATGGPIPQRWENVEEPNLDELLVRLEEEQ--QRCESLAEVN 117
Query: 314 EKIQEQEEKIREQEEKIREQEEKM-----RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368
+++ EK + +RE EK+ R ++E+M KE + + ++E + +
Sbjct: 118 TQLRLHMEKADVVNKALREDVEKLTVDWSRARDELM-RKESQWQMEQEFFKGYLKGEHGR 176
Query: 369 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 428
+W + RR M K R+L E E ++ + Q +
Sbjct: 177 LLSLWREVVTFRRHFLEM--KSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNG 234
Query: 429 EAKM-WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
+M R+ ++ K +E EK+ HE+ + + K Q E ++++ E
Sbjct: 235 SGRMDGREPAQLLLLLAKTQELEKEA-------HERSQELIQLKSQGDLEKAELQDRVTE 287
Query: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR--QEEKIREQEE 545
+ Q +K +E EK+ K + E + ++ E E + R QEEK+ Q+
Sbjct: 288 LSALLTQSQKQNEDYEKMIKALRET---VEILETNHTELMEHEASLSRNAQEEKLSLQQV 344
Query: 546 MWREEEKMHEQ-EKIWE---EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
+ + M E+ + I + E E + ++ Q + ++ ++ + + + + Q
Sbjct: 345 IKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFD-YQDADKALTLVRSVLTRRRQAVQ 403
Query: 602 EQEEKMWKQEEKI---REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
+ +++ +E + ++Q ++ +E+ + +R++ +K+ + + Q + + + + +
Sbjct: 404 DLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSK 463
Query: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
+ E +Q+ E + +Q E + ++ ++R +++ Q + Q Q+E+ E+ + E+
Sbjct: 464 ERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERER 523
Query: 719 MQEQEEKMRRQEEKMWEQEVRLRQQEE 745
+QE + ++ + + + LR+ E
Sbjct: 524 LQEMLMGLEAKQSESLSELITLREALE 550
Score = 58.5 bits (140), Expect = 2e-08
Identities = 92/429 (21%), Positives = 172/429 (40%), Gaps = 50/429 (11%)
Query: 106 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
S E E+ Q+ + E +V T R L + Q L ++ L E++
Sbjct: 1896 SREQEKALLALQQQCAEQAQEHEVET-RALQDSWLQAQAVLKERDQELEALRAESQSSRH 1954
Query: 166 RLHDSWKFAGELEQALS-AVATQKKKADRYIE--ELTKERDALSLELYRNTITDEELKEK 222
+ + A L++AL A A + K +E EL++ +A + L + + +
Sbjct: 1955 QEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASL---DACQAH 2011
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282
+ +L+E L++ E E + L +E ++L++A Q E H + Q + L
Sbjct: 2012 SRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALA-----QRDEELRHQQEREQLLEKSLA 2066
Query: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
+V+EN + + N QE R+EE+I+ + ++E + + ++E++I E E +R
Sbjct: 2067 QRVQENMIQEKQNLGQE----REEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNL 2122
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL------ 396
K EE + + R + + + +R+ E E EK ++L
Sbjct: 2123 EALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQ 2182
Query: 397 ---------EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW------------RQ 435
E M Q + E++ ++Q + E +R ++ ++ R
Sbjct: 2183 TKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRG 2242
Query: 436 EEKIR-------EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488
E+ ++ E E EK+ WRQ + +Q R E R + Q EQ
Sbjct: 2243 EQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQ 2302
Query: 489 EEIWRQKEK 497
E R+K K
Sbjct: 2303 VERERRKLK 2311
Score = 34.7 bits (78), Expect = 0.33
Identities = 63/319 (19%), Positives = 125/319 (39%), Gaps = 45/319 (14%)
Query: 474 EQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK----IRKQEEKVWRQEEKIREQEEKIREQ 529
E++ + Q++ Q WR+ + E +++ +RK + KV + +E E+++
Sbjct: 21 EEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEAT 80
Query: 530 E---EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE-DKMWRQEEKIREQEEK 585
+ W E+ E + R EE+ E + E + +K + +RE EK
Sbjct: 81 GGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEK 140
Query: 586 V---WRQ--EEKIREQEEKRQEQEE-------------KMWKQEEKIREQ--EEKIQEQE 625
+ W + +E +R++ + + EQE +W++ R E K
Sbjct: 141 LTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDR 200
Query: 626 EKIREQEEKIREQEEM-TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKI 684
+ + + E +R + T +G Q + + + K +E EK+
Sbjct: 201 DLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEA 260
Query: 685 REQEEKI--------REQEEMMQEQEE--KMWEQEEKMCEQEEKM----QEQEEKMRRQE 730
E+ +++ E+ E+ E + Q +K E EKM +E E +
Sbjct: 261 HERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH 320
Query: 731 EKMWEQEVRLRQ--QEEKM 747
++ E E L + QEEK+
Sbjct: 321 TELMEHEASLSRNAQEEKL 339
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 150 bits (380), Expect = 3e-36
Identities = 159/700 (22%), Positives = 337/700 (48%), Gaps = 89/700 (12%)
Query: 112 KASHQHQEALRRELEAQVHTIR------ILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
KAS + A + ELE ++ IR + + ++ EL+ A + + E R+
Sbjct: 1931 KASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAAR--QRQLAAEEERRRREAEE 1988
Query: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
R+ S E + A + ++ +EE + R+ E R +E +K +
Sbjct: 1989 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
+EK ++ E +EL++ L++ + +L Q + +AEA E ++ A++QA+
Sbjct: 2049 AEEKAHAFAVQQKE-----QELQQTLQQEQSVLDQLRGEAEAARRAAE-EAEEARVQAER 2102
Query: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
E + +R ++ E++ + E+ + + Q EK+R++ E +E RR +
Sbjct: 2103 EAAQ--SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAE-----QEAARRAQAEQA 2155
Query: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
+K EM EK +K E+ +R++ ++ E +LEE H++
Sbjct: 2156 ALRQKQAADAEM--EKHKKFA---------EQTLRQKAQVEQELTTLRLQLEETDHQKNL 2204
Query: 406 IREQEEKRQEE--EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
+ E+ ++ + E E R++ + +E+ + Q E++ + + +I E E + +K + Q
Sbjct: 2205 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI-EAENRALILRDKDNTQ 2263
Query: 464 EKIREEEKRQEQ--EEMWR--------------QEEKIHEQEEIWRQ--KEKMHEQEE-- 503
++EE ++ +Q EE R EE + +Q + + KEKM +E
Sbjct: 2264 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2323
Query: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
+++ + E + +Q+E +EQ +++E +E+M +Q + + + E E+ + E E E
Sbjct: 2324 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2383
Query: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ--EQEEKMWKQEEKIREQE--- 618
+ + + +M R + + E ++ +Q E+I E+ + + QE+ Q +I+ Q+
Sbjct: 2384 RLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH 2443
Query: 619 --EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE-QEEKMCEQEEKMQEQ---EETMWR 672
E+++E ++ ++EK++++ ++ Q + E+M Q+E++ ++ + +Q+ E+
Sbjct: 2444 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2503
Query: 673 QEEKIREQEKKIREQ-------------EEKIREQEEMMQEQEE----------KMWEQE 709
Q E+ EQEK EQ EE+ R+Q++M QE++ + E E
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 710 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
E + ++E++Q+ E++ R+QEE + E+ RLR+Q + ++E
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2603
Score = 137 bits (344), Expect = 5e-32
Identities = 153/673 (22%), Positives = 306/673 (45%), Gaps = 66/673 (9%)
Query: 106 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
SP + K + ++ ++ + H + T ++ + ++++E E R
Sbjct: 1298 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK----FISETLRRMEEEERLAEQ 1353
Query: 166 RLHDSWKFAGELEQALS-------AVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
+ + + E+E AL A A K +A+R +EL + + E+ R +
Sbjct: 1354 QRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVD 1410
Query: 219 LKEKNAKLQEKLQ-LVESEKSEIQLNVKELKRKLERAKLLLPQQ----QLQAEADHLGK- 272
+++ +QE+LQ L +S ++EIQ ++ + ER++L + ++ +LQ EA +
Sbjct: 1411 AQQQKRSIQEELQQLRQSSEAEIQAKARQAEAA-ERSRLRIEEEIRVVRLQLEATERQRG 1469
Query: 273 ----ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
ELQ+ L+A+ EE E R Q++ E++ RQ +Q++ ++ R+ E
Sbjct: 1470 GAEGELQA----LRARAEEAEAQKRQAQEEAERLRRQ----------VQDESQRKRQAEV 1515
Query: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
++ +++ + E EK+ ++ EE+ + EE RR + E+ +++ E
Sbjct: 1516 ELAS---RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1572
Query: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
E EL+ K + Q E+ +EE + + R+E E + +Q E R +EE RE
Sbjct: 1573 SAEA--ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1630
Query: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
E R + K +E ++R + + Q++ Q E ++EE R+ + + EE+ +Q
Sbjct: 1631 LE----RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1686
Query: 509 EEKVWRQEEKIRE------QEEKIREQEEKMWRQEEKIREQEEMWREEEKMH-EQEKIWE 561
E ++ EK R+ Q+ EQE R E + EQ+ EEE ++E
Sbjct: 1687 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1746
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE-------KMWKQEEKI 614
+KRQE E ++ + ++ R EE+ R EK +++ E ++ ++ ++
Sbjct: 1747 TQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL 1806
Query: 615 REQEEKIQEQEEKIREQEEKIR-EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
R E+ + Q + E + R E E + E+ +GE E E ++E+E R
Sbjct: 1807 RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1866
Query: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
++ + R EE+ + + ++E+ ++ + + E+++ + E + RRQ E
Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVE-- 1924
Query: 734 WEQEVRLRQQEEK 746
E+ + L+ EK
Sbjct: 1925 -EEILALKASFEK 1936
Score = 135 bits (339), Expect = 2e-31
Identities = 149/659 (22%), Positives = 301/659 (45%), Gaps = 42/659 (6%)
Query: 106 SPEDEQKASHQHQEALRRE---LEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
S E E +A + EA R +E ++ +R L + TE Q ++ ++ L A +
Sbjct: 1428 SSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRG--GAEGELQALRARAEE 1484
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
++ + + A L + + + +K++A+ + K + E R EEL+ +
Sbjct: 1485 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1544
Query: 223 NAKLQEKLQLVESEKS-EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
+ + +L+ E E++ ++Q+ ++ +R E A+L + + L + LQ +
Sbjct: 1545 AEEAERRLRQAEVERARQVQVALETAQRSAE-AELQSKRASFAEKTAQLERSLQEEHVAV 1603
Query: 282 QAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
EE E R QQ E + R+E +++ W+ K E ++R Q E++ +Q+ +
Sbjct: 1604 AQLREEAE--RRAQQQAEAERAREEAERELERWQLKANEAL-RLRLQAEEVAQQKSLAQA 1660
Query: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR------QEEMMWEKEE-K 392
+ E +++E+ R+ + EE+ RQ E+ ++ EK R+ Q+ + E+E +
Sbjct: 1661 EAE---KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR 1717
Query: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
+R E+ +Q ++ E+E R + E +KRQE EA++ K+R + E + + +
Sbjct: 1718 LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL----AKVRAEMEVLLASKAR 1773
Query: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEK 511
+ E+ K R E + E+ + ++ EE RQ++ E + R + E+
Sbjct: 1774 AEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER 1833
Query: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
V EK+ E R + E +EK E E + R E Q + EE+ Q + D
Sbjct: 1834 VLA--EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADI 1891
Query: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE---EKIREQEEKIQEQEEKI 628
R + + + ++ RQ+ + + +R++ EE++ + EK + +++ + +I
Sbjct: 1892 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRI 1951
Query: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ---EEKIREQEKKIR 685
R E +E + E + Q + E+E + +E EE + + EE+ Q K
Sbjct: 1952 RSNAEDTLRSKE---QAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL 2008
Query: 686 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
E+ E+++ + E + E+ E++ Q + QE +K + EEK V+ ++QE
Sbjct: 2009 EEVERLKAKVEEARRLRER---AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2064
Score = 134 bits (337), Expect = 3e-31
Identities = 145/687 (21%), Positives = 322/687 (46%), Gaps = 74/687 (10%)
Query: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ-HAVKQLEGEARDLISRL 167
+EQ A H + ++E ++ +R + + E Q L +Q+E E L +
Sbjct: 1881 EEQAAQH------KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1934
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ ELE L + + + R +KE+ L R +EE + + A+ +
Sbjct: 1935 EKAAAGKAELELELGRIRSNAEDTLR-----SKEQAELEAARQRQLAAEEERRRREAEER 1989
Query: 228 EKLQLVESEKSEIQLN-----VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282
+ L E++ Q V+ LK K+E A+ L + + Q A L ++ +LQ
Sbjct: 1990 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE-QESARQLQLAQEAAQKRLQ 2048
Query: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
A+ + + + +Q+ ++ +QE+ + + E + E+ E+ R Q E+ Q
Sbjct: 2049 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2108
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 402
E+ E++++ E ++ + R Q + EK K QE + E+ L +K
Sbjct: 2109 RQVEEAERLKQSAE----EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAA-LRQK--- 2160
Query: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE--EKI 460
Q E E+ ++ E+ Q+ + EQE R + + + ++ + ++E + + E E
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2220
Query: 461 HEQEKIREE--EKRQEQEEMWRQEEKIHEQEE--IWRQKEK----MHEQEEKIRKQEEKV 512
++ ++ EE R + EE+ + + +I + I R K+ + E+ EK+++ E+
Sbjct: 2221 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2280
Query: 513 WRQEEKIREQ-------EEKIREQE---EKMWRQE-EKIREQEEMWREEEKMHEQEKIWE 561
R +E EE + +Q EKM +++ + ++E + E E + +Q+++ +
Sbjct: 2281 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ 2340
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
E+ R+ QEDK + +++ E+ + R E R+++ + + E++ + ++ + +
Sbjct: 2341 EQARRLQEDKE-QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2399
Query: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
+E ++ R+Q E+I E+ T+ + QE+ Q ++Q Q+ E++RE
Sbjct: 2400 EEDAQRFRKQAEEIGEKLHRTE-----LATQEKVTLVQTLEIQRQQSD--HDAERLREAI 2452
Query: 682 KKIREQEEKIREQEEMMQ-EQEEKMWEQEEKMCEQEEKMQE----------QEEKMRRQE 730
++ ++EK++++ +++Q + EE Q+E++ ++ + +Q+ Q E+ QE
Sbjct: 2453 AELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQE 2512
Query: 731 ----EKMWEQEV----RLRQQEEKMQE 749
E++++ EV +LR+++++ Q+
Sbjct: 2513 KAKLEQLFQDEVAKAQQLREEQQRQQQ 2539
Score = 132 bits (332), Expect = 1e-30
Identities = 185/781 (23%), Positives = 349/781 (44%), Gaps = 132/781 (16%)
Query: 66 QLTDHHPQTNPSVGTAASDTKKKKINNGTNP-------------ETTT---------SGG 103
QL + Q P AS KK K+ +G+ E TT S
Sbjct: 1285 QLVTYKAQLEP----VASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1340
Query: 104 CHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDL 163
E+E++ + Q Q A RE A+V + + Q+A ++Q A Q E EA++L
Sbjct: 1341 LRRMEEEERLAEQ-QRAEERERLAEVEA-----ALEKQRQLAEAHAQ-AKAQAEREAKEL 1393
Query: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
R+ + + + +AV Q++K EEL + R + E+ E +
Sbjct: 1394 QQRMQEE-----VVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSR 1447
Query: 224 AKLQEKLQLV-------ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
+++E++++V E ++ + ++ L+ + E A+ ++Q Q EA+ L +++Q
Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA--QKRQAQEEAERLRRQVQD 1505
Query: 277 VSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
S K QA+VE L +R+ + E R++++ + E+++ Q E E E ++R+ E
Sbjct: 1506 ESQRKRQAEVE---LASRVKAEAEAA--REKQRALQALEELRLQAE---EAERRLRQAEV 1557
Query: 336 KMRRQEEMMWEK-----EEKMRRQEEMMWEKEEKMRR--QEE------MMWEKEEKMRRQ 382
+ RQ ++ E E +++ + EK ++ R QEE + E E + ++Q
Sbjct: 1558 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ 1617
Query: 383 EEMMWEKEEKIRELE----------------EKMHEQEKIREQEEKRQEEEKIREQEKRQ 426
E +EE RELE E++ +Q+ + + E ++Q+EE RE +R
Sbjct: 1618 AEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG 1677
Query: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE--KIREEEKRQEQEEMWRQEEK 484
+ E + RQ E + EQE + + Q + Q+ EQE ++R E ++ EQ+ +EE
Sbjct: 1678 KAEEQAVRQRE-LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1736
Query: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVW-------RQEEKIREQEEKIREQ-EEKMWRQ 536
Q E +K E E ++ K ++ R EE+ R EK +++ E + R
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 537 EEKIREQEEMWREEEKMHEQEKIWEEE---KRQEQE----DKMWRQEEKIREQEEKVWRQ 589
E E + E+ Q ++ EE+ +R E E +K+ E R + E
Sbjct: 1797 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1856
Query: 590 EEKIREQEEKRQEQEEKMWKQ---EEKIREQEEKIQEQEEKIREQ------------EEK 634
+EK E E R+ E++ +++ EE+ + + I+E+ ++R+ E+
Sbjct: 1857 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1916
Query: 635 IREQEEMTQE-------QEEKMGEQEEKMCEQEEKMQEQEETMWRQEE---KIREQEKKI 684
+R++ ++ +E E+ + E E E+T+ +E+ + Q +
Sbjct: 1917 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976
Query: 685 REQEEKIREQEEMMQEQ---EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
E+E + RE EE +Q+ EE+ Q + E+ E+++ + E+ RR E+ ++ R
Sbjct: 1977 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2036
Query: 742 Q 742
Q
Sbjct: 2037 Q 2037
Score = 131 bits (329), Expect = 3e-30
Identities = 166/736 (22%), Positives = 323/736 (43%), Gaps = 83/736 (11%)
Query: 54 ETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKA 113
+ RQ +L + QL + +P +G D ++++ P D Q
Sbjct: 1196 DVRQRELEQLGRQLRYYRESADP-LGAWLQDARRRQEQIQAMPLA----------DSQAV 1244
Query: 114 SHQ--HQEALRRELEAQVHTIRILTCQKT-----------ELQMALYYSQHAVKQLEGEA 160
Q ++AL E+E H ++ CQ+ ELQ+ Y +Q +
Sbjct: 1245 REQLRQEQALLEEIER--HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1302
Query: 161 RDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE-LTKERDALSLELYRNTITDEEL 219
+ S + +L S + T + ++I E L + + L + E L
Sbjct: 1303 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERL 1362
Query: 220 KEKNAKLQEKLQLVESE---KSEIQLNVKELKRKLERAKL------LLPQQQLQAEADHL 270
E A L+++ QL E+ K++ + KEL+++++ + + QQQ ++ + L
Sbjct: 1363 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1422
Query: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
+ QS A++QA+ + E R + EE++ ++ E + Q + + +
Sbjct: 1423 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEI----RVVRLQLEATERQRGGAEGELQAL 1478
Query: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
R + E+ Q+ E+ E++RRQ + E + +RQ E+ E +++ + E EK+
Sbjct: 1479 RARAEEAEAQKRQAQEEAERLRRQVQ----DESQRKRQAEV--ELASRVKAEAEAAREKQ 1532
Query: 391 EKIRELEEKMHEQE----KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
++ LEE + E ++R+ E +R + ++ + ++ EA++ + K EK
Sbjct: 1533 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKT 1589
Query: 447 REQEKKMWRQEEKIHEQEKIREEEKR-QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
+ E+ + QEE + + E E+R Q+Q E R E+ + E W+ K + ++
Sbjct: 1590 AQLERSL--QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKAN---EALRL 1644
Query: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE--EEKMHEQEKIWEEE 563
R Q E+V +Q+ + + EK +E+ E+ R+ K EQ RE E+++ +Q ++ E
Sbjct: 1645 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1704
Query: 564 KRQ----EQEDKMWRQEEKIREQ-----EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
+Q EQE R E + EQ EE++ R + + +KRQE E ++ K+
Sbjct: 1705 AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL----AKV 1760
Query: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
R + E + K R +EE E+ Q E + G E + E+ +++ E RQ
Sbjct: 1761 RAEMEVLLAS--KARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAKRQR 1817
Query: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
+ E + R + E++ + E+ + E E E ++E+E + R
Sbjct: 1818 QLAEEDAARQRAEAERV------LAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1871
Query: 735 EQEVRLRQQEEKMQEH 750
++ + R+ EE+ +H
Sbjct: 1872 DEAFQRRRLEEQAAQH 1887
Score = 115 bits (288), Expect = 1e-25
Identities = 152/734 (20%), Positives = 329/734 (44%), Gaps = 108/734 (14%)
Query: 119 EALRRELEAQVHTIRILTCQKT-ELQMALYYSQHAVKQLEGEA-------------RDLI 164
E +R EA++ + R +KT +L+ +L AV QL EA R+
Sbjct: 1568 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1627
Query: 165 SRLHDSWKF-----------AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT 213
R + W+ A E+ Q S + +K E + R + R
Sbjct: 1628 ERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR 1687
Query: 214 ITDEELKEKNAKLQEKL--QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
E+ EK +L E Q + +E+ I+L + + + +R L +LQ EA
Sbjct: 1688 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1747
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
++ Q + A+L E E+ + EE+ EK ++ E + ++ E+ ++R
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-------EKMRRQEEM-MWEKE---EKMR 380
E+ +RQ ++ E + R + E + ++ +++ + E+ + EKE E++R
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1867
Query: 381 RQEEMMWEKEEKIRE--------LEEKMHEQEKIREQEEKRQE---EEKIREQEKRQEQ- 428
R E + ++ E +EE++ + K + E +RQ+ E+ +R++ + +E+
Sbjct: 1868 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1927
Query: 429 -------------EAKMWRQEEKIREQ-EEKIREQEK---KMWRQEEKIHEQEKIREEEK 471
+A++ + +IR E+ +R +E+ + RQ + E+E+ R E +
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 472 RQEQEEMWRQEEKIHEQ----EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
+ Q+ + +EE ++ EE+ R K K+ E + E++ RQ + +E +K
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2047
Query: 528 EQEEKM--WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ--EQEDKMWRQEEKIREQE 583
+ EEK + ++K +E ++ ++E+ + +Q + E R+ E+ ++ Q E+ Q
Sbjct: 2048 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2107
Query: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR---EQEEKIQEQEEK--IREQ------- 631
+ + E++++ E++ + + EK+R EQE + Q E+ +R++
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Query: 632 -------EEKIREQEEMTQE------QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
E+ +R++ ++ QE Q E+ Q+ + E+ ++++ + RQ ++
Sbjct: 2168 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2227
Query: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK------ 732
E+ +R Q E++ + + ++ + + +++ + +QE+ EKM++ E+
Sbjct: 2228 EELFSVRVQMEELSKLKARIEAENRALILRDKD--NTQRFLQEEAEKMKQVAEEAARLSV 2285
Query: 733 MWEQEVRLRQQEEK 746
++ RLRQ E+
Sbjct: 2286 AAQEAARLRQLAEE 2299
Score = 114 bits (285), Expect = 3e-25
Identities = 120/550 (21%), Positives = 251/550 (45%), Gaps = 46/550 (8%)
Query: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
E +E+ A+L E+ Q V ++ Q +++L R+L + + AD LG LQ
Sbjct: 1175 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQL---------RYYRESADPLGAWLQD 1225
Query: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
+ Q Q++ L + Q + RQE+ + E +I+ EK+ E + ++
Sbjct: 1226 ARRR-QEQIQAMPL---ADSQAVREQLRQEQALLE---EIERHGEKVEECQRFAKQYINA 1278
Query: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
++ E + + ++ +K + E ++ E + E+ + I+ +
Sbjct: 1279 IKDYELQLVTYKAQLEPVASPA-KKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFI 1337
Query: 397 EE---KMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQEEK---IR 447
E +M E+E++ EQ ++ +E E++ E E ++Q Q A+ Q + E+E K R
Sbjct: 1338 SETLRRMEEEERLAEQ-QRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1396
Query: 448 EQEKKMWRQEEKIHEQEK---IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
QE+ + R+E + Q++ I+EE ++ Q + K + E R + ++ E+
Sbjct: 1397 MQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1456
Query: 505 IRKQEEKVWRQE-------EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557
+R Q E RQ + +R + E+ Q+ + + E++R Q + + ++ E E
Sbjct: 1457 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1516
Query: 558 ---KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
++ E + ++ + + E++R Q E+ E ++R+ E +R Q + + ++
Sbjct: 1517 LASRVKAEAEAAREKQRALQALEELRLQAEEA---ERRLRQAEVERARQVQVALETAQRS 1573
Query: 615 REQE--EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
E E K EK + E ++E+ + E+ + ++ E E +E E + R
Sbjct: 1574 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1633
Query: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
+ K E ++R Q E++ +Q+ + Q + EK E+ E+ + K +EQ + R E+
Sbjct: 1634 WQLKANE-ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1692
Query: 733 MWEQEVRLRQ 742
E++ +L +
Sbjct: 1693 ELEKQRQLAE 1702
Score = 99.0 bits (245), Expect = 1e-20
Identities = 169/801 (21%), Positives = 328/801 (40%), Gaps = 118/801 (14%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P P HPM + + + ++T H VG A K ++G+ +
Sbjct: 796 PRHPAHPMRGRLPLLAVCDYKQVEVTVHKGDECQLVGPAQPSHWKVLSSSGSEAAVPSVC 855
Query: 103 GCHSPEDEQ--------KASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVK 154
P +++ +A HQ L +L + ++ + ++Q+ +S +
Sbjct: 856 FLVPPPNQEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFR 915
Query: 155 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE--LTKERDALSLELYRN 212
L+ E + LH LE A + A + E L ER+ S +
Sbjct: 916 TLKPEEQR--QALHS-------LELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQ 966
Query: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--------------ERAKLLL 258
+ E+ A+ + + Q SE +I+L ++ + + E A+ +
Sbjct: 967 QLLQS--LEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIA 1024
Query: 259 PQQQLQAEADHLGKELQSVSA---KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315
QQ+ QAE + LGK + +SA K+ A E + L + E + + E+ ++
Sbjct: 1025 EQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ-VRSLSAI 1083
Query: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--EKMRRQEEMMW 373
E+ + I + EE +R EE + E + E+ K +K+R Q E
Sbjct: 1084 YLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQ 1143
Query: 374 EKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQEEKRQE--EEKIREQEKRQEQEA 430
+ +R + E E++++ E+ E E+ RE+ + E + + + + RQ +
Sbjct: 1144 PTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELE 1203
Query: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIH-----EQEKIREEEKRQEQ---EEMWRQE 482
++ RQ RE + + + R++E+I + + +R E+ RQEQ EE+ R
Sbjct: 1204 QLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVR-EQLRQEQALLEEIERHG 1262
Query: 483 EKIHEQEEIWRQ---------------KEKMH-----EQEEKIRKQEEKVWRQ------- 515
EK+ E + +Q K ++ ++ K++ E V ++
Sbjct: 1263 EKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTH 1322
Query: 516 ---------------EEKIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQE 557
E +R EE+ R E++ + E++ E E E R+ + H Q
Sbjct: 1323 YSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA 1382
Query: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
K E + +E + +M QEE +R +E V Q++K QEE +Q ++ + + K R+
Sbjct: 1383 KAQAEREAKELQQRM--QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1440
Query: 618 EE------KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
E +I+E+ +R Q E Q + + + + + E+ Q+ + QE+ E +
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1500
Query: 672 R--QEEKIREQE------KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
R Q+E R+++ +++ + E RE++ +Q EE + E E E ++++ E
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE----EAERRLRQAE 1556
Query: 724 EKMRRQEEKMWEQEVRLRQQE 744
+ RQ + E R + E
Sbjct: 1557 VERARQVQVALETAQRSAEAE 1577
Score = 70.9 bits (172), Expect = 4e-12
Identities = 76/326 (23%), Positives = 159/326 (48%), Gaps = 45/326 (13%)
Query: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
Q + + L+ ++ ++ T K E ++ ++Q + A++ RL +
Sbjct: 2303 QQRALAEKMLKEKMQAVQEATRLKAEAEL--------LQQQKELAQEQARRLQE------ 2348
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
+ EQ +A + + R +E + + +S E R + E+ A+ +E Q
Sbjct: 2349 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2408
Query: 236 EKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
+ EI +L+ EL + E+ L+ + + ++DH + L+ A+L+ + E+ + +
Sbjct: 2409 QAEEIGEKLHRTELATQ-EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2467
Query: 294 LNQQQEEKMW--RQEEKIQEWEEKIQE---------QEEKIREQEEKIREQ--EEKMRRQ 340
L Q + E+M +QE+ +QE + Q Q E+ EQE+ EQ ++++ +
Sbjct: 2468 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2527
Query: 341 EEMMWEKEEKMRRQEEMMWEK-------EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
+++ +EE+ R+Q++M E+ EE RRQ E EE +RR++E + + E++
Sbjct: 2528 QQL---REEQQRQQQQMEQERQRLVASMEEARRRQH----EAEEGVRRKQEELQQLEQQR 2580
Query: 394 RELEEKM-HEQEKIREQEEKRQEEEK 418
R+ EE + E +++REQ + +E+ +
Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHR 2606
Score = 51.2 bits (121), Expect = 3e-06
Identities = 100/538 (18%), Positives = 217/538 (40%), Gaps = 80/538 (14%)
Query: 272 KELQSVSAKLQAQVEEN-ELWNRLNQQQE-----EKMWRQEEKIQEWE----EKIQEQEE 321
+E Q +L+AQ + LW++L+ + + + R + I+ W ++ +E+
Sbjct: 863 QEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQ 922
Query: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 381
+ ++ Q Q+ + E+++ + E + + + +E+ R
Sbjct: 923 RQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRC 982
Query: 382 QEEMMWEKEEKIRELE----EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Q + K+ ++ +LE +H ++E R+ ++I EQ+K Q + + +
Sbjct: 983 QRCISELKDIRL-QLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVA 1041
Query: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
++ + EK+ + R E E + E++ I+ +K K
Sbjct: 1042 RLSAEAEKVLALP------------EPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLK 1089
Query: 498 M--------HEQEEKIRKQEEKVWRQE---------EKIREQEEKIREQEEKMWRQEEKI 540
EE +R EE++ + E + +K+R Q E + +
Sbjct: 1090 TISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDAL 1149
Query: 541 REQ----EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ 596
R++ +E+ ++ H + + E E+ +E+ ++ + + + Q + R+ E++ Q
Sbjct: 1150 RDELRGAQEVGERLQQRHGERDV-EVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1208
Query: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQ----EEKIREQEEKIREQEEMTQEQEEKMGEQ 652
+E + + + R ++E+IQ + +REQ QE+ E+ E+ GE+
Sbjct: 1209 LRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ----LRQEQALLEEIERHGEK 1264
Query: 653 EEKMCEQEEKM--------QEQEETMWRQEEKIREQEKKIREQ---EEKIREQEEMMQEQ 701
E+ C++ K + Q T Q E + KK + Q E I+E ++
Sbjct: 1265 VEE-CQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHY 1323
Query: 702 EE---------KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
E K + + E+EE++ EQ+ R E++ E E L +Q + + H
Sbjct: 1324 SELTTLTSQYIKFISETLRRMEEEERLAEQQRAEER--ERLAEVEAALEKQRQLAEAH 1379
Score = 30.4 bits (67), Expect = 6.3
Identities = 35/200 (17%), Positives = 84/200 (42%), Gaps = 9/200 (4%)
Query: 62 EAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQ--KASHQHQE 119
E + Q +DH + A + +K+K+ S + + EQ + + Q+
Sbjct: 2435 EIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2493
Query: 120 ALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQ 179
+ E ++ + R + +K +L+ +QL E + ++ E ++
Sbjct: 2494 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ------ERQR 2547
Query: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
++++ +++ E + ++++ L + +E L E+N +L+E+LQL+E +
Sbjct: 2548 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2607
Query: 240 IQLNVKELKRKLERAKLLLP 259
+ +E+ A LP
Sbjct: 2608 ALAHSEEVTASQVAATKTLP 2627
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 150 bits (380), Expect = 3e-36
Identities = 159/700 (22%), Positives = 337/700 (48%), Gaps = 89/700 (12%)
Query: 112 KASHQHQEALRRELEAQVHTIR------ILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
KAS + A + ELE ++ IR + + ++ EL+ A + + E R+
Sbjct: 1935 KASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAAR--QRQLAAEEERRRREAEE 1992
Query: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
R+ S E + A + ++ +EE + R+ E R +E +K +
Sbjct: 1993 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2052
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
+EK ++ E +EL++ L++ + +L Q + +AEA E ++ A++QA+
Sbjct: 2053 AEEKAHAFAVQQKE-----QELQQTLQQEQSVLDQLRGEAEAARRAAE-EAEEARVQAER 2106
Query: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
E + +R ++ E++ + E+ + + Q EK+R++ E +E RR +
Sbjct: 2107 EAAQ--SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAE-----QEAARRAQAEQA 2159
Query: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
+K EM EK +K E+ +R++ ++ E +LEE H++
Sbjct: 2160 ALRQKQAADAEM--EKHKKFA---------EQTLRQKAQVEQELTTLRLQLEETDHQKNL 2208
Query: 406 IREQEEKRQEE--EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
+ E+ ++ + E E R++ + +E+ + Q E++ + + +I E E + +K + Q
Sbjct: 2209 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI-EAENRALILRDKDNTQ 2267
Query: 464 EKIREEEKRQEQ--EEMWR--------------QEEKIHEQEEIWRQ--KEKMHEQEE-- 503
++EE ++ +Q EE R EE + +Q + + KEKM +E
Sbjct: 2268 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2327
Query: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
+++ + E + +Q+E +EQ +++E +E+M +Q + + + E E+ + E E E
Sbjct: 2328 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2387
Query: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ--EQEEKMWKQEEKIREQE--- 618
+ + + +M R + + E ++ +Q E+I E+ + + QE+ Q +I+ Q+
Sbjct: 2388 RLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH 2447
Query: 619 --EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE-QEEKMCEQEEKMQEQ---EETMWR 672
E+++E ++ ++EK++++ ++ Q + E+M Q+E++ ++ + +Q+ E+
Sbjct: 2448 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2507
Query: 673 QEEKIREQEKKIREQ-------------EEKIREQEEMMQEQEE----------KMWEQE 709
Q E+ EQEK EQ EE+ R+Q++M QE++ + E E
Sbjct: 2508 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2567
Query: 710 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
E + ++E++Q+ E++ R+QEE + E+ RLR+Q + ++E
Sbjct: 2568 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2607
Score = 137 bits (344), Expect = 5e-32
Identities = 153/673 (22%), Positives = 306/673 (45%), Gaps = 66/673 (9%)
Query: 106 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
SP + K + ++ ++ + H + T ++ + ++++E E R
Sbjct: 1302 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK----FISETLRRMEEEERLAEQ 1357
Query: 166 RLHDSWKFAGELEQALS-------AVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
+ + + E+E AL A A K +A+R +EL + + E+ R +
Sbjct: 1358 QRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVD 1414
Query: 219 LKEKNAKLQEKLQ-LVESEKSEIQLNVKELKRKLERAKLLLPQQ----QLQAEADHLGK- 272
+++ +QE+LQ L +S ++EIQ ++ + ER++L + ++ +LQ EA +
Sbjct: 1415 AQQQKRSIQEELQQLRQSSEAEIQAKARQAEAA-ERSRLRIEEEIRVVRLQLEATERQRG 1473
Query: 273 ----ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
ELQ+ L+A+ EE E R Q++ E++ RQ +Q++ ++ R+ E
Sbjct: 1474 GAEGELQA----LRARAEEAEAQKRQAQEEAERLRRQ----------VQDESQRKRQAEV 1519
Query: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
++ +++ + E EK+ ++ EE+ + EE RR + E+ +++ E
Sbjct: 1520 ELAS---RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1576
Query: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
E EL+ K + Q E+ +EE + + R+E E + +Q E R +EE RE
Sbjct: 1577 SAEA--ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1634
Query: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
E R + K +E ++R + + Q++ Q E ++EE R+ + + EE+ +Q
Sbjct: 1635 LE----RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1690
Query: 509 EEKVWRQEEKIRE------QEEKIREQEEKMWRQEEKIREQEEMWREEEKMH-EQEKIWE 561
E ++ EK R+ Q+ EQE R E + EQ+ EEE ++E
Sbjct: 1691 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1750
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE-------KMWKQEEKI 614
+KRQE E ++ + ++ R EE+ R EK +++ E ++ ++ ++
Sbjct: 1751 TQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL 1810
Query: 615 REQEEKIQEQEEKIREQEEKIR-EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
R E+ + Q + E + R E E + E+ +GE E E ++E+E R
Sbjct: 1811 RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1870
Query: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
++ + R EE+ + + ++E+ ++ + + E+++ + E + RRQ E
Sbjct: 1871 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVE-- 1928
Query: 734 WEQEVRLRQQEEK 746
E+ + L+ EK
Sbjct: 1929 -EEILALKASFEK 1940
Score = 135 bits (339), Expect = 2e-31
Identities = 149/659 (22%), Positives = 301/659 (45%), Gaps = 42/659 (6%)
Query: 106 SPEDEQKASHQHQEALRRE---LEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
S E E +A + EA R +E ++ +R L + TE Q ++ ++ L A +
Sbjct: 1432 SSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRG--GAEGELQALRARAEE 1488
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
++ + + A L + + + +K++A+ + K + E R EEL+ +
Sbjct: 1489 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1548
Query: 223 NAKLQEKLQLVESEKS-EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
+ + +L+ E E++ ++Q+ ++ +R E A+L + + L + LQ +
Sbjct: 1549 AEEAERRLRQAEVERARQVQVALETAQRSAE-AELQSKRASFAEKTAQLERSLQEEHVAV 1607
Query: 282 QAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
EE E R QQ E + R+E +++ W+ K E ++R Q E++ +Q+ +
Sbjct: 1608 AQLREEAE--RRAQQQAEAERAREEAERELERWQLKANEAL-RLRLQAEEVAQQKSLAQA 1664
Query: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR------QEEMMWEKEE-K 392
+ E +++E+ R+ + EE+ RQ E+ ++ EK R+ Q+ + E+E +
Sbjct: 1665 EAE---KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR 1721
Query: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
+R E+ +Q ++ E+E R + E +KRQE EA++ K+R + E + + +
Sbjct: 1722 LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL----AKVRAEMEVLLASKAR 1777
Query: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEK 511
+ E+ K R E + E+ + ++ EE RQ++ E + R + E+
Sbjct: 1778 AEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER 1837
Query: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
V EK+ E R + E +EK E E + R E Q + EE+ Q + D
Sbjct: 1838 VLA--EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADI 1895
Query: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE---EKIREQEEKIQEQEEKI 628
R + + + ++ RQ+ + + +R++ EE++ + EK + +++ + +I
Sbjct: 1896 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRI 1955
Query: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ---EEKIREQEKKIR 685
R E +E + E + Q + E+E + +E EE + + EE+ Q K
Sbjct: 1956 RSNAEDTLRSKE---QAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL 2012
Query: 686 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
E+ E+++ + E + E+ E++ Q + QE +K + EEK V+ ++QE
Sbjct: 2013 EEVERLKAKVEEARRLRER---AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2068
Score = 134 bits (337), Expect = 3e-31
Identities = 145/687 (21%), Positives = 322/687 (46%), Gaps = 74/687 (10%)
Query: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ-HAVKQLEGEARDLISRL 167
+EQ A H + ++E ++ +R + + E Q L +Q+E E L +
Sbjct: 1885 EEQAAQH------KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1938
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ ELE L + + + R +KE+ L R +EE + + A+ +
Sbjct: 1939 EKAAAGKAELELELGRIRSNAEDTLR-----SKEQAELEAARQRQLAAEEERRRREAEER 1993
Query: 228 EKLQLVESEKSEIQLN-----VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282
+ L E++ Q V+ LK K+E A+ L + + Q A L ++ +LQ
Sbjct: 1994 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE-QESARQLQLAQEAAQKRLQ 2052
Query: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
A+ + + + +Q+ ++ +QE+ + + E + E+ E+ R Q E+ Q
Sbjct: 2053 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2112
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 402
E+ E++++ E ++ + R Q + EK K QE + E+ L +K
Sbjct: 2113 RQVEEAERLKQSAE----EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAA-LRQK--- 2164
Query: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE--EKI 460
Q E E+ ++ E+ Q+ + EQE R + + + ++ + ++E + + E E
Sbjct: 2165 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2224
Query: 461 HEQEKIREE--EKRQEQEEMWRQEEKIHEQEE--IWRQKEK----MHEQEEKIRKQEEKV 512
++ ++ EE R + EE+ + + +I + I R K+ + E+ EK+++ E+
Sbjct: 2225 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2284
Query: 513 WRQEEKIREQ-------EEKIREQE---EKMWRQE-EKIREQEEMWREEEKMHEQEKIWE 561
R +E EE + +Q EKM +++ + ++E + E E + +Q+++ +
Sbjct: 2285 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ 2344
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
E+ R+ QEDK + +++ E+ + R E R+++ + + E++ + ++ + +
Sbjct: 2345 EQARRLQEDKE-QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2403
Query: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
+E ++ R+Q E+I E+ T+ + QE+ Q ++Q Q+ E++RE
Sbjct: 2404 EEDAQRFRKQAEEIGEKLHRTE-----LATQEKVTLVQTLEIQRQQSD--HDAERLREAI 2456
Query: 682 KKIREQEEKIREQEEMMQ-EQEEKMWEQEEKMCEQEEKMQE----------QEEKMRRQE 730
++ ++EK++++ +++Q + EE Q+E++ ++ + +Q+ Q E+ QE
Sbjct: 2457 AELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQE 2516
Query: 731 ----EKMWEQEV----RLRQQEEKMQE 749
E++++ EV +LR+++++ Q+
Sbjct: 2517 KAKLEQLFQDEVAKAQQLREEQQRQQQ 2543
Score = 132 bits (332), Expect = 1e-30
Identities = 185/781 (23%), Positives = 349/781 (44%), Gaps = 132/781 (16%)
Query: 66 QLTDHHPQTNPSVGTAASDTKKKKINNGTNP-------------ETTT---------SGG 103
QL + Q P AS KK K+ +G+ E TT S
Sbjct: 1289 QLVTYKAQLEP----VASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1344
Query: 104 CHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDL 163
E+E++ + Q Q A RE A+V + + Q+A ++Q A Q E EA++L
Sbjct: 1345 LRRMEEEERLAEQ-QRAEERERLAEVEA-----ALEKQRQLAEAHAQ-AKAQAEREAKEL 1397
Query: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
R+ + + + +AV Q++K EEL + R + E+ E +
Sbjct: 1398 QQRMQEE-----VVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSR 1451
Query: 224 AKLQEKLQLV-------ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
+++E++++V E ++ + ++ L+ + E A+ ++Q Q EA+ L +++Q
Sbjct: 1452 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA--QKRQAQEEAERLRRQVQD 1509
Query: 277 VSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
S K QA+VE L +R+ + E R++++ + E+++ Q E E E ++R+ E
Sbjct: 1510 ESQRKRQAEVE---LASRVKAEAEAA--REKQRALQALEELRLQAE---EAERRLRQAEV 1561
Query: 336 KMRRQEEMMWEK-----EEKMRRQEEMMWEKEEKMRR--QEE------MMWEKEEKMRRQ 382
+ RQ ++ E E +++ + EK ++ R QEE + E E + ++Q
Sbjct: 1562 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ 1621
Query: 383 EEMMWEKEEKIRELE----------------EKMHEQEKIREQEEKRQEEEKIREQEKRQ 426
E +EE RELE E++ +Q+ + + E ++Q+EE RE +R
Sbjct: 1622 AEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG 1681
Query: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE--KIREEEKRQEQEEMWRQEEK 484
+ E + RQ E + EQE + + Q + Q+ EQE ++R E ++ EQ+ +EE
Sbjct: 1682 KAEEQAVRQRE-LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1740
Query: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVW-------RQEEKIREQEEKIREQ-EEKMWRQ 536
Q E +K E E ++ K ++ R EE+ R EK +++ E + R
Sbjct: 1741 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1800
Query: 537 EEKIREQEEMWREEEKMHEQEKIWEEE---KRQEQE----DKMWRQEEKIREQEEKVWRQ 589
E E + E+ Q ++ EE+ +R E E +K+ E R + E
Sbjct: 1801 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1860
Query: 590 EEKIREQEEKRQEQEEKMWKQ---EEKIREQEEKIQEQEEKIREQ------------EEK 634
+EK E E R+ E++ +++ EE+ + + I+E+ ++R+ E+
Sbjct: 1861 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1920
Query: 635 IREQEEMTQE-------QEEKMGEQEEKMCEQEEKMQEQEETMWRQEE---KIREQEKKI 684
+R++ ++ +E E+ + E E E+T+ +E+ + Q +
Sbjct: 1921 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1980
Query: 685 REQEEKIREQEEMMQEQ---EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
E+E + RE EE +Q+ EE+ Q + E+ E+++ + E+ RR E+ ++ R
Sbjct: 1981 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2040
Query: 742 Q 742
Q
Sbjct: 2041 Q 2041
Score = 131 bits (329), Expect = 3e-30
Identities = 166/736 (22%), Positives = 323/736 (43%), Gaps = 83/736 (11%)
Query: 54 ETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKA 113
+ RQ +L + QL + +P +G D ++++ P D Q
Sbjct: 1200 DVRQRELEQLGRQLRYYRESADP-LGAWLQDARRRQEQIQAMPLA----------DSQAV 1248
Query: 114 SHQ--HQEALRRELEAQVHTIRILTCQKT-----------ELQMALYYSQHAVKQLEGEA 160
Q ++AL E+E H ++ CQ+ ELQ+ Y +Q +
Sbjct: 1249 REQLRQEQALLEEIER--HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1306
Query: 161 RDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE-LTKERDALSLELYRNTITDEEL 219
+ S + +L S + T + ++I E L + + L + E L
Sbjct: 1307 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERL 1366
Query: 220 KEKNAKLQEKLQLVESE---KSEIQLNVKELKRKLERAKL------LLPQQQLQAEADHL 270
E A L+++ QL E+ K++ + KEL+++++ + + QQQ ++ + L
Sbjct: 1367 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1426
Query: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
+ QS A++QA+ + E R + EE++ ++ E + Q + + +
Sbjct: 1427 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEI----RVVRLQLEATERQRGGAEGELQAL 1482
Query: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
R + E+ Q+ E+ E++RRQ + E + +RQ E+ E +++ + E EK+
Sbjct: 1483 RARAEEAEAQKRQAQEEAERLRRQVQ----DESQRKRQAEV--ELASRVKAEAEAAREKQ 1536
Query: 391 EKIRELEEKMHEQE----KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
++ LEE + E ++R+ E +R + ++ + ++ EA++ + K EK
Sbjct: 1537 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKT 1593
Query: 447 REQEKKMWRQEEKIHEQEKIREEEKR-QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
+ E+ + QEE + + E E+R Q+Q E R E+ + E W+ K + ++
Sbjct: 1594 AQLERSL--QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKAN---EALRL 1648
Query: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE--EEKMHEQEKIWEEE 563
R Q E+V +Q+ + + EK +E+ E+ R+ K EQ RE E+++ +Q ++ E
Sbjct: 1649 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1708
Query: 564 KRQ----EQEDKMWRQEEKIREQ-----EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
+Q EQE R E + EQ EE++ R + + +KRQE E ++ K+
Sbjct: 1709 AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL----AKV 1764
Query: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
R + E + K R +EE E+ Q E + G E + E+ +++ E RQ
Sbjct: 1765 RAEMEVLLAS--KARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAKRQR 1821
Query: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
+ E + R + E++ + E+ + E E E ++E+E + R
Sbjct: 1822 QLAEEDAARQRAEAERV------LAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1875
Query: 735 EQEVRLRQQEEKMQEH 750
++ + R+ EE+ +H
Sbjct: 1876 DEAFQRRRLEEQAAQH 1891
Score = 115 bits (288), Expect = 1e-25
Identities = 152/734 (20%), Positives = 329/734 (44%), Gaps = 108/734 (14%)
Query: 119 EALRRELEAQVHTIRILTCQKT-ELQMALYYSQHAVKQLEGEA-------------RDLI 164
E +R EA++ + R +KT +L+ +L AV QL EA R+
Sbjct: 1572 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1631
Query: 165 SRLHDSWKF-----------AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT 213
R + W+ A E+ Q S + +K E + R + R
Sbjct: 1632 ERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR 1691
Query: 214 ITDEELKEKNAKLQEKL--QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
E+ EK +L E Q + +E+ I+L + + + +R L +LQ EA
Sbjct: 1692 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1751
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
++ Q + A+L E E+ + EE+ EK ++ E + ++ E+ ++R
Sbjct: 1752 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1811
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-------EKMRRQEEM-MWEKE---EKMR 380
E+ +RQ ++ E + R + E + ++ +++ + E+ + EKE E++R
Sbjct: 1812 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1871
Query: 381 RQEEMMWEKEEKIRE--------LEEKMHEQEKIREQEEKRQE---EEKIREQEKRQEQ- 428
R E + ++ E +EE++ + K + E +RQ+ E+ +R++ + +E+
Sbjct: 1872 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1931
Query: 429 -------------EAKMWRQEEKIREQ-EEKIREQEK---KMWRQEEKIHEQEKIREEEK 471
+A++ + +IR E+ +R +E+ + RQ + E+E+ R E +
Sbjct: 1932 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1991
Query: 472 RQEQEEMWRQEEKIHEQ----EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
+ Q+ + +EE ++ EE+ R K K+ E + E++ RQ + +E +K
Sbjct: 1992 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2051
Query: 528 EQEEKM--WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ--EQEDKMWRQEEKIREQE 583
+ EEK + ++K +E ++ ++E+ + +Q + E R+ E+ ++ Q E+ Q
Sbjct: 2052 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2111
Query: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR---EQEEKIQEQEEK--IREQ------- 631
+ + E++++ E++ + + EK+R EQE + Q E+ +R++
Sbjct: 2112 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2171
Query: 632 -------EEKIREQEEMTQE------QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
E+ +R++ ++ QE Q E+ Q+ + E+ ++++ + RQ ++
Sbjct: 2172 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2231
Query: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK------ 732
E+ +R Q E++ + + ++ + + +++ + +QE+ EKM++ E+
Sbjct: 2232 EELFSVRVQMEELSKLKARIEAENRALILRDKD--NTQRFLQEEAEKMKQVAEEAARLSV 2289
Query: 733 MWEQEVRLRQQEEK 746
++ RLRQ E+
Sbjct: 2290 AAQEAARLRQLAEE 2303
Score = 114 bits (285), Expect = 3e-25
Identities = 120/550 (21%), Positives = 251/550 (45%), Gaps = 46/550 (8%)
Query: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
E +E+ A+L E+ Q V ++ Q +++L R+L + + AD LG LQ
Sbjct: 1179 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQL---------RYYRESADPLGAWLQD 1229
Query: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
+ Q Q++ L + Q + RQE+ + E +I+ EK+ E + ++
Sbjct: 1230 ARRR-QEQIQAMPL---ADSQAVREQLRQEQALLE---EIERHGEKVEECQRFAKQYINA 1282
Query: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
++ E + + ++ +K + E ++ E + E+ + I+ +
Sbjct: 1283 IKDYELQLVTYKAQLEPVASPA-KKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFI 1341
Query: 397 EE---KMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQEEK---IR 447
E +M E+E++ EQ ++ +E E++ E E ++Q Q A+ Q + E+E K R
Sbjct: 1342 SETLRRMEEEERLAEQ-QRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1400
Query: 448 EQEKKMWRQEEKIHEQEK---IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
QE+ + R+E + Q++ I+EE ++ Q + K + E R + ++ E+
Sbjct: 1401 MQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1460
Query: 505 IRKQEEKVWRQE-------EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557
+R Q E RQ + +R + E+ Q+ + + E++R Q + + ++ E E
Sbjct: 1461 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1520
Query: 558 ---KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
++ E + ++ + + E++R Q E+ E ++R+ E +R Q + + ++
Sbjct: 1521 LASRVKAEAEAAREKQRALQALEELRLQAEEA---ERRLRQAEVERARQVQVALETAQRS 1577
Query: 615 REQE--EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
E E K EK + E ++E+ + E+ + ++ E E +E E + R
Sbjct: 1578 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1637
Query: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
+ K E ++R Q E++ +Q+ + Q + EK E+ E+ + K +EQ + R E+
Sbjct: 1638 WQLKANE-ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1696
Query: 733 MWEQEVRLRQ 742
E++ +L +
Sbjct: 1697 ELEKQRQLAE 1706
Score = 99.0 bits (245), Expect = 1e-20
Identities = 169/801 (21%), Positives = 328/801 (40%), Gaps = 118/801 (14%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P P HPM + + + ++T H VG A K ++G+ +
Sbjct: 800 PRHPAHPMRGRLPLLAVCDYKQVEVTVHKGDECQLVGPAQPSHWKVLSSSGSEAAVPSVC 859
Query: 103 GCHSPEDEQ--------KASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVK 154
P +++ +A HQ L +L + ++ + ++Q+ +S +
Sbjct: 860 FLVPPPNQEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFR 919
Query: 155 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE--LTKERDALSLELYRN 212
L+ E + LH LE A + A + E L ER+ S +
Sbjct: 920 TLKPEEQR--QALHS-------LELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQ 970
Query: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--------------ERAKLLL 258
+ E+ A+ + + Q SE +I+L ++ + + E A+ +
Sbjct: 971 QLLQS--LEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIA 1028
Query: 259 PQQQLQAEADHLGKELQSVSA---KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315
QQ+ QAE + LGK + +SA K+ A E + L + E + + E+ ++
Sbjct: 1029 EQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ-VRSLSAI 1087
Query: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--EKMRRQEEMMW 373
E+ + I + EE +R EE + E + E+ K +K+R Q E
Sbjct: 1088 YLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQ 1147
Query: 374 EKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQEEKRQE--EEKIREQEKRQEQEA 430
+ +R + E E++++ E+ E E+ RE+ + E + + + + RQ +
Sbjct: 1148 PTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELE 1207
Query: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIH-----EQEKIREEEKRQEQ---EEMWRQE 482
++ RQ RE + + + R++E+I + + +R E+ RQEQ EE+ R
Sbjct: 1208 QLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVR-EQLRQEQALLEEIERHG 1266
Query: 483 EKIHEQEEIWRQ---------------KEKMH-----EQEEKIRKQEEKVWRQ------- 515
EK+ E + +Q K ++ ++ K++ E V ++
Sbjct: 1267 EKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTH 1326
Query: 516 ---------------EEKIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQE 557
E +R EE+ R E++ + E++ E E E R+ + H Q
Sbjct: 1327 YSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA 1386
Query: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
K E + +E + +M QEE +R +E V Q++K QEE +Q ++ + + K R+
Sbjct: 1387 KAQAEREAKELQQRM--QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1444
Query: 618 EE------KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
E +I+E+ +R Q E Q + + + + + E+ Q+ + QE+ E +
Sbjct: 1445 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1504
Query: 672 R--QEEKIREQE------KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
R Q+E R+++ +++ + E RE++ +Q EE + E E E ++++ E
Sbjct: 1505 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE----EAERRLRQAE 1560
Query: 724 EKMRRQEEKMWEQEVRLRQQE 744
+ RQ + E R + E
Sbjct: 1561 VERARQVQVALETAQRSAEAE 1581
Score = 70.9 bits (172), Expect = 4e-12
Identities = 76/326 (23%), Positives = 159/326 (48%), Gaps = 45/326 (13%)
Query: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
Q + + L+ ++ ++ T K E ++ ++Q + A++ RL +
Sbjct: 2307 QQRALAEKMLKEKMQAVQEATRLKAEAEL--------LQQQKELAQEQARRLQE------ 2352
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
+ EQ +A + + R +E + + +S E R + E+ A+ +E Q
Sbjct: 2353 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2412
Query: 236 EKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
+ EI +L+ EL + E+ L+ + + ++DH + L+ A+L+ + E+ + +
Sbjct: 2413 QAEEIGEKLHRTELATQ-EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2471
Query: 294 LNQQQEEKMW--RQEEKIQEWEEKIQE---------QEEKIREQEEKIREQ--EEKMRRQ 340
L Q + E+M +QE+ +QE + Q Q E+ EQE+ EQ ++++ +
Sbjct: 2472 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2531
Query: 341 EEMMWEKEEKMRRQEEMMWEK-------EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
+++ +EE+ R+Q++M E+ EE RRQ E EE +RR++E + + E++
Sbjct: 2532 QQL---REEQQRQQQQMEQERQRLVASMEEARRRQH----EAEEGVRRKQEELQQLEQQR 2584
Query: 394 RELEEKM-HEQEKIREQEEKRQEEEK 418
R+ EE + E +++REQ + +E+ +
Sbjct: 2585 RQQEELLAEENQRLREQLQLLEEQHR 2610
Score = 51.2 bits (121), Expect = 3e-06
Identities = 100/538 (18%), Positives = 217/538 (40%), Gaps = 80/538 (14%)
Query: 272 KELQSVSAKLQAQVEEN-ELWNRLNQQQE-----EKMWRQEEKIQEWE----EKIQEQEE 321
+E Q +L+AQ + LW++L+ + + + R + I+ W ++ +E+
Sbjct: 867 QEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQ 926
Query: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 381
+ ++ Q Q+ + E+++ + E + + + +E+ R
Sbjct: 927 RQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRC 986
Query: 382 QEEMMWEKEEKIRELE----EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Q + K+ ++ +LE +H ++E R+ ++I EQ+K Q + + +
Sbjct: 987 QRCISELKDIRL-QLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVA 1045
Query: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
++ + EK+ + R E E + E++ I+ +K K
Sbjct: 1046 RLSAEAEKVLALP------------EPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLK 1093
Query: 498 M--------HEQEEKIRKQEEKVWRQE---------EKIREQEEKIREQEEKMWRQEEKI 540
EE +R EE++ + E + +K+R Q E + +
Sbjct: 1094 TISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDAL 1153
Query: 541 REQ----EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ 596
R++ +E+ ++ H + + E E+ +E+ ++ + + + Q + R+ E++ Q
Sbjct: 1154 RDELRGAQEVGERLQQRHGERDV-EVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1212
Query: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQ----EEKIREQEEKIREQEEMTQEQEEKMGEQ 652
+E + + + R ++E+IQ + +REQ QE+ E+ E+ GE+
Sbjct: 1213 LRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ----LRQEQALLEEIERHGEK 1268
Query: 653 EEKMCEQEEKM--------QEQEETMWRQEEKIREQEKKIREQ---EEKIREQEEMMQEQ 701
E+ C++ K + Q T Q E + KK + Q E I+E ++
Sbjct: 1269 VEE-CQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHY 1327
Query: 702 EE---------KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
E K + + E+EE++ EQ+ R E++ E E L +Q + + H
Sbjct: 1328 SELTTLTSQYIKFISETLRRMEEEERLAEQQRAEER--ERLAEVEAALEKQRQLAEAH 1383
Score = 30.4 bits (67), Expect = 6.3
Identities = 35/200 (17%), Positives = 84/200 (42%), Gaps = 9/200 (4%)
Query: 62 EAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQ--KASHQHQE 119
E + Q +DH + A + +K+K+ S + + EQ + + Q+
Sbjct: 2439 EIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2497
Query: 120 ALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQ 179
+ E ++ + R + +K +L+ +QL E + ++ E ++
Sbjct: 2498 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ------ERQR 2551
Query: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
++++ +++ E + ++++ L + +E L E+N +L+E+LQL+E +
Sbjct: 2552 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2611
Query: 240 IQLNVKELKRKLERAKLLLP 259
+ +E+ A LP
Sbjct: 2612 ALAHSEEVTASQVAATKTLP 2631
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 150 bits (380), Expect = 3e-36
Identities = 159/700 (22%), Positives = 337/700 (48%), Gaps = 89/700 (12%)
Query: 112 KASHQHQEALRRELEAQVHTIR------ILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
KAS + A + ELE ++ IR + + ++ EL+ A + + E R+
Sbjct: 1931 KASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAAR--QRQLAAEEERRRREAEE 1988
Query: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
R+ S E + A + ++ +EE + R+ E R +E +K +
Sbjct: 1989 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2048
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
+EK ++ E +EL++ L++ + +L Q + +AEA E ++ A++QA+
Sbjct: 2049 AEEKAHAFAVQQKE-----QELQQTLQQEQSVLDQLRGEAEAARRAAE-EAEEARVQAER 2102
Query: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
E + +R ++ E++ + E+ + + Q EK+R++ E +E RR +
Sbjct: 2103 EAAQ--SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAE-----QEAARRAQAEQA 2155
Query: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
+K EM EK +K E+ +R++ ++ E +LEE H++
Sbjct: 2156 ALRQKQAADAEM--EKHKKFA---------EQTLRQKAQVEQELTTLRLQLEETDHQKNL 2204
Query: 406 IREQEEKRQEE--EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
+ E+ ++ + E E R++ + +E+ + Q E++ + + +I E E + +K + Q
Sbjct: 2205 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI-EAENRALILRDKDNTQ 2263
Query: 464 EKIREEEKRQEQ--EEMWR--------------QEEKIHEQEEIWRQ--KEKMHEQEE-- 503
++EE ++ +Q EE R EE + +Q + + KEKM +E
Sbjct: 2264 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2323
Query: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
+++ + E + +Q+E +EQ +++E +E+M +Q + + + E E+ + E E E
Sbjct: 2324 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2383
Query: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ--EQEEKMWKQEEKIREQE--- 618
+ + + +M R + + E ++ +Q E+I E+ + + QE+ Q +I+ Q+
Sbjct: 2384 RLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH 2443
Query: 619 --EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE-QEEKMCEQEEKMQEQ---EETMWR 672
E+++E ++ ++EK++++ ++ Q + E+M Q+E++ ++ + +Q+ E+
Sbjct: 2444 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2503
Query: 673 QEEKIREQEKKIREQ-------------EEKIREQEEMMQEQEE----------KMWEQE 709
Q E+ EQEK EQ EE+ R+Q++M QE++ + E E
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 710 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
E + ++E++Q+ E++ R+QEE + E+ RLR+Q + ++E
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2603
Score = 137 bits (344), Expect = 5e-32
Identities = 153/673 (22%), Positives = 306/673 (45%), Gaps = 66/673 (9%)
Query: 106 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
SP + K + ++ ++ + H + T ++ + ++++E E R
Sbjct: 1298 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK----FISETLRRMEEEERLAEQ 1353
Query: 166 RLHDSWKFAGELEQALS-------AVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
+ + + E+E AL A A K +A+R +EL + + E+ R +
Sbjct: 1354 QRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVD 1410
Query: 219 LKEKNAKLQEKLQ-LVESEKSEIQLNVKELKRKLERAKLLLPQQ----QLQAEADHLGK- 272
+++ +QE+LQ L +S ++EIQ ++ + ER++L + ++ +LQ EA +
Sbjct: 1411 AQQQKRSIQEELQQLRQSSEAEIQAKARQAEAA-ERSRLRIEEEIRVVRLQLEATERQRG 1469
Query: 273 ----ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
ELQ+ L+A+ EE E R Q++ E++ RQ +Q++ ++ R+ E
Sbjct: 1470 GAEGELQA----LRARAEEAEAQKRQAQEEAERLRRQ----------VQDESQRKRQAEV 1515
Query: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
++ +++ + E EK+ ++ EE+ + EE RR + E+ +++ E
Sbjct: 1516 ELAS---RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1572
Query: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
E EL+ K + Q E+ +EE + + R+E E + +Q E R +EE RE
Sbjct: 1573 SAEA--ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1630
Query: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
E R + K +E ++R + + Q++ Q E ++EE R+ + + EE+ +Q
Sbjct: 1631 LE----RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1686
Query: 509 EEKVWRQEEKIRE------QEEKIREQEEKMWRQEEKIREQEEMWREEEKMH-EQEKIWE 561
E ++ EK R+ Q+ EQE R E + EQ+ EEE ++E
Sbjct: 1687 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1746
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE-------KMWKQEEKI 614
+KRQE E ++ + ++ R EE+ R EK +++ E ++ ++ ++
Sbjct: 1747 TQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL 1806
Query: 615 REQEEKIQEQEEKIREQEEKIR-EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
R E+ + Q + E + R E E + E+ +GE E E ++E+E R
Sbjct: 1807 RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1866
Query: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
++ + R EE+ + + ++E+ ++ + + E+++ + E + RRQ E
Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVE-- 1924
Query: 734 WEQEVRLRQQEEK 746
E+ + L+ EK
Sbjct: 1925 -EEILALKASFEK 1936
Score = 135 bits (339), Expect = 2e-31
Identities = 149/659 (22%), Positives = 301/659 (45%), Gaps = 42/659 (6%)
Query: 106 SPEDEQKASHQHQEALRRE---LEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
S E E +A + EA R +E ++ +R L + TE Q ++ ++ L A +
Sbjct: 1428 SSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRG--GAEGELQALRARAEE 1484
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
++ + + A L + + + +K++A+ + K + E R EEL+ +
Sbjct: 1485 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1544
Query: 223 NAKLQEKLQLVESEKS-EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
+ + +L+ E E++ ++Q+ ++ +R E A+L + + L + LQ +
Sbjct: 1545 AEEAERRLRQAEVERARQVQVALETAQRSAE-AELQSKRASFAEKTAQLERSLQEEHVAV 1603
Query: 282 QAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
EE E R QQ E + R+E +++ W+ K E ++R Q E++ +Q+ +
Sbjct: 1604 AQLREEAE--RRAQQQAEAERAREEAERELERWQLKANEAL-RLRLQAEEVAQQKSLAQA 1660
Query: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR------QEEMMWEKEE-K 392
+ E +++E+ R+ + EE+ RQ E+ ++ EK R+ Q+ + E+E +
Sbjct: 1661 EAE---KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR 1717
Query: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
+R E+ +Q ++ E+E R + E +KRQE EA++ K+R + E + + +
Sbjct: 1718 LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL----AKVRAEMEVLLASKAR 1773
Query: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEK 511
+ E+ K R E + E+ + ++ EE RQ++ E + R + E+
Sbjct: 1774 AEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER 1833
Query: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
V EK+ E R + E +EK E E + R E Q + EE+ Q + D
Sbjct: 1834 VLA--EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADI 1891
Query: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE---EKIREQEEKIQEQEEKI 628
R + + + ++ RQ+ + + +R++ EE++ + EK + +++ + +I
Sbjct: 1892 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRI 1951
Query: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ---EEKIREQEKKIR 685
R E +E + E + Q + E+E + +E EE + + EE+ Q K
Sbjct: 1952 RSNAEDTLRSKE---QAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL 2008
Query: 686 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
E+ E+++ + E + E+ E++ Q + QE +K + EEK V+ ++QE
Sbjct: 2009 EEVERLKAKVEEARRLRER---AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2064
Score = 134 bits (337), Expect = 3e-31
Identities = 145/687 (21%), Positives = 322/687 (46%), Gaps = 74/687 (10%)
Query: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ-HAVKQLEGEARDLISRL 167
+EQ A H + ++E ++ +R + + E Q L +Q+E E L +
Sbjct: 1881 EEQAAQH------KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1934
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ ELE L + + + R +KE+ L R +EE + + A+ +
Sbjct: 1935 EKAAAGKAELELELGRIRSNAEDTLR-----SKEQAELEAARQRQLAAEEERRRREAEER 1989
Query: 228 EKLQLVESEKSEIQLN-----VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282
+ L E++ Q V+ LK K+E A+ L + + Q A L ++ +LQ
Sbjct: 1990 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE-QESARQLQLAQEAAQKRLQ 2048
Query: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
A+ + + + +Q+ ++ +QE+ + + E + E+ E+ R Q E+ Q
Sbjct: 2049 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2108
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 402
E+ E++++ E ++ + R Q + EK K QE + E+ L +K
Sbjct: 2109 RQVEEAERLKQSAE----EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAA-LRQK--- 2160
Query: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE--EKI 460
Q E E+ ++ E+ Q+ + EQE R + + + ++ + ++E + + E E
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2220
Query: 461 HEQEKIREE--EKRQEQEEMWRQEEKIHEQEE--IWRQKEK----MHEQEEKIRKQEEKV 512
++ ++ EE R + EE+ + + +I + I R K+ + E+ EK+++ E+
Sbjct: 2221 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2280
Query: 513 WRQEEKIREQ-------EEKIREQE---EKMWRQE-EKIREQEEMWREEEKMHEQEKIWE 561
R +E EE + +Q EKM +++ + ++E + E E + +Q+++ +
Sbjct: 2281 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ 2340
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
E+ R+ QEDK + +++ E+ + R E R+++ + + E++ + ++ + +
Sbjct: 2341 EQARRLQEDKE-QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2399
Query: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
+E ++ R+Q E+I E+ T+ + QE+ Q ++Q Q+ E++RE
Sbjct: 2400 EEDAQRFRKQAEEIGEKLHRTE-----LATQEKVTLVQTLEIQRQQSD--HDAERLREAI 2452
Query: 682 KKIREQEEKIREQEEMMQ-EQEEKMWEQEEKMCEQEEKMQE----------QEEKMRRQE 730
++ ++EK++++ +++Q + EE Q+E++ ++ + +Q+ Q E+ QE
Sbjct: 2453 AELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQE 2512
Query: 731 ----EKMWEQEV----RLRQQEEKMQE 749
E++++ EV +LR+++++ Q+
Sbjct: 2513 KAKLEQLFQDEVAKAQQLREEQQRQQQ 2539
Score = 132 bits (332), Expect = 1e-30
Identities = 185/781 (23%), Positives = 349/781 (44%), Gaps = 132/781 (16%)
Query: 66 QLTDHHPQTNPSVGTAASDTKKKKINNGTNP-------------ETTT---------SGG 103
QL + Q P AS KK K+ +G+ E TT S
Sbjct: 1285 QLVTYKAQLEP----VASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1340
Query: 104 CHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDL 163
E+E++ + Q Q A RE A+V + + Q+A ++Q A Q E EA++L
Sbjct: 1341 LRRMEEEERLAEQ-QRAEERERLAEVEA-----ALEKQRQLAEAHAQ-AKAQAEREAKEL 1393
Query: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
R+ + + + +AV Q++K EEL + R + E+ E +
Sbjct: 1394 QQRMQEE-----VVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSR 1447
Query: 224 AKLQEKLQLV-------ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
+++E++++V E ++ + ++ L+ + E A+ ++Q Q EA+ L +++Q
Sbjct: 1448 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA--QKRQAQEEAERLRRQVQD 1505
Query: 277 VSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
S K QA+VE L +R+ + E R++++ + E+++ Q E E E ++R+ E
Sbjct: 1506 ESQRKRQAEVE---LASRVKAEAEAA--REKQRALQALEELRLQAE---EAERRLRQAEV 1557
Query: 336 KMRRQEEMMWEK-----EEKMRRQEEMMWEKEEKMRR--QEE------MMWEKEEKMRRQ 382
+ RQ ++ E E +++ + EK ++ R QEE + E E + ++Q
Sbjct: 1558 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ 1617
Query: 383 EEMMWEKEEKIRELE----------------EKMHEQEKIREQEEKRQEEEKIREQEKRQ 426
E +EE RELE E++ +Q+ + + E ++Q+EE RE +R
Sbjct: 1618 AEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG 1677
Query: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE--KIREEEKRQEQEEMWRQEEK 484
+ E + RQ E + EQE + + Q + Q+ EQE ++R E ++ EQ+ +EE
Sbjct: 1678 KAEEQAVRQRE-LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1736
Query: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVW-------RQEEKIREQEEKIREQ-EEKMWRQ 536
Q E +K E E ++ K ++ R EE+ R EK +++ E + R
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 537 EEKIREQEEMWREEEKMHEQEKIWEEE---KRQEQE----DKMWRQEEKIREQEEKVWRQ 589
E E + E+ Q ++ EE+ +R E E +K+ E R + E
Sbjct: 1797 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1856
Query: 590 EEKIREQEEKRQEQEEKMWKQ---EEKIREQEEKIQEQEEKIREQ------------EEK 634
+EK E E R+ E++ +++ EE+ + + I+E+ ++R+ E+
Sbjct: 1857 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1916
Query: 635 IREQEEMTQE-------QEEKMGEQEEKMCEQEEKMQEQEETMWRQEE---KIREQEKKI 684
+R++ ++ +E E+ + E E E+T+ +E+ + Q +
Sbjct: 1917 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976
Query: 685 REQEEKIREQEEMMQEQ---EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
E+E + RE EE +Q+ EE+ Q + E+ E+++ + E+ RR E+ ++ R
Sbjct: 1977 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2036
Query: 742 Q 742
Q
Sbjct: 2037 Q 2037
Score = 131 bits (329), Expect = 3e-30
Identities = 166/736 (22%), Positives = 323/736 (43%), Gaps = 83/736 (11%)
Query: 54 ETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKA 113
+ RQ +L + QL + +P +G D ++++ P D Q
Sbjct: 1196 DVRQRELEQLGRQLRYYRESADP-LGAWLQDARRRQEQIQAMPLA----------DSQAV 1244
Query: 114 SHQ--HQEALRRELEAQVHTIRILTCQKT-----------ELQMALYYSQHAVKQLEGEA 160
Q ++AL E+E H ++ CQ+ ELQ+ Y +Q +
Sbjct: 1245 REQLRQEQALLEEIER--HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1302
Query: 161 RDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE-LTKERDALSLELYRNTITDEEL 219
+ S + +L S + T + ++I E L + + L + E L
Sbjct: 1303 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERL 1362
Query: 220 KEKNAKLQEKLQLVESE---KSEIQLNVKELKRKLERAKL------LLPQQQLQAEADHL 270
E A L+++ QL E+ K++ + KEL+++++ + + QQQ ++ + L
Sbjct: 1363 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1422
Query: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
+ QS A++QA+ + E R + EE++ ++ E + Q + + +
Sbjct: 1423 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEI----RVVRLQLEATERQRGGAEGELQAL 1478
Query: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
R + E+ Q+ E+ E++RRQ + E + +RQ E+ E +++ + E EK+
Sbjct: 1479 RARAEEAEAQKRQAQEEAERLRRQVQ----DESQRKRQAEV--ELASRVKAEAEAAREKQ 1532
Query: 391 EKIRELEEKMHEQE----KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
++ LEE + E ++R+ E +R + ++ + ++ EA++ + K EK
Sbjct: 1533 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKT 1589
Query: 447 REQEKKMWRQEEKIHEQEKIREEEKR-QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
+ E+ + QEE + + E E+R Q+Q E R E+ + E W+ K + ++
Sbjct: 1590 AQLERSL--QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKAN---EALRL 1644
Query: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE--EEKMHEQEKIWEEE 563
R Q E+V +Q+ + + EK +E+ E+ R+ K EQ RE E+++ +Q ++ E
Sbjct: 1645 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1704
Query: 564 KRQ----EQEDKMWRQEEKIREQ-----EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
+Q EQE R E + EQ EE++ R + + +KRQE E ++ K+
Sbjct: 1705 AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL----AKV 1760
Query: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
R + E + K R +EE E+ Q E + G E + E+ +++ E RQ
Sbjct: 1761 RAEMEVLLAS--KARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAKRQR 1817
Query: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
+ E + R + E++ + E+ + E E E ++E+E + R
Sbjct: 1818 QLAEEDAARQRAEAERV------LAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1871
Query: 735 EQEVRLRQQEEKMQEH 750
++ + R+ EE+ +H
Sbjct: 1872 DEAFQRRRLEEQAAQH 1887
Score = 115 bits (288), Expect = 1e-25
Identities = 152/734 (20%), Positives = 329/734 (44%), Gaps = 108/734 (14%)
Query: 119 EALRRELEAQVHTIRILTCQKT-ELQMALYYSQHAVKQLEGEA-------------RDLI 164
E +R EA++ + R +KT +L+ +L AV QL EA R+
Sbjct: 1568 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1627
Query: 165 SRLHDSWKF-----------AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT 213
R + W+ A E+ Q S + +K E + R + R
Sbjct: 1628 ERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR 1687
Query: 214 ITDEELKEKNAKLQEKL--QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
E+ EK +L E Q + +E+ I+L + + + +R L +LQ EA
Sbjct: 1688 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1747
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
++ Q + A+L E E+ + EE+ EK ++ E + ++ E+ ++R
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-------EKMRRQEEM-MWEKE---EKMR 380
E+ +RQ ++ E + R + E + ++ +++ + E+ + EKE E++R
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1867
Query: 381 RQEEMMWEKEEKIRE--------LEEKMHEQEKIREQEEKRQE---EEKIREQEKRQEQ- 428
R E + ++ E +EE++ + K + E +RQ+ E+ +R++ + +E+
Sbjct: 1868 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1927
Query: 429 -------------EAKMWRQEEKIREQ-EEKIREQEK---KMWRQEEKIHEQEKIREEEK 471
+A++ + +IR E+ +R +E+ + RQ + E+E+ R E +
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 472 RQEQEEMWRQEEKIHEQ----EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
+ Q+ + +EE ++ EE+ R K K+ E + E++ RQ + +E +K
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2047
Query: 528 EQEEKM--WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ--EQEDKMWRQEEKIREQE 583
+ EEK + ++K +E ++ ++E+ + +Q + E R+ E+ ++ Q E+ Q
Sbjct: 2048 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2107
Query: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR---EQEEKIQEQEEK--IREQ------- 631
+ + E++++ E++ + + EK+R EQE + Q E+ +R++
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Query: 632 -------EEKIREQEEMTQE------QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
E+ +R++ ++ QE Q E+ Q+ + E+ ++++ + RQ ++
Sbjct: 2168 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2227
Query: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK------ 732
E+ +R Q E++ + + ++ + + +++ + +QE+ EKM++ E+
Sbjct: 2228 EELFSVRVQMEELSKLKARIEAENRALILRDKD--NTQRFLQEEAEKMKQVAEEAARLSV 2285
Query: 733 MWEQEVRLRQQEEK 746
++ RLRQ E+
Sbjct: 2286 AAQEAARLRQLAEE 2299
Score = 114 bits (285), Expect = 3e-25
Identities = 120/550 (21%), Positives = 251/550 (45%), Gaps = 46/550 (8%)
Query: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
E +E+ A+L E+ Q V ++ Q +++L R+L + + AD LG LQ
Sbjct: 1175 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQL---------RYYRESADPLGAWLQD 1225
Query: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
+ Q Q++ L + Q + RQE+ + E +I+ EK+ E + ++
Sbjct: 1226 ARRR-QEQIQAMPL---ADSQAVREQLRQEQALLE---EIERHGEKVEECQRFAKQYINA 1278
Query: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
++ E + + ++ +K + E ++ E + E+ + I+ +
Sbjct: 1279 IKDYELQLVTYKAQLEPVASPA-KKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFI 1337
Query: 397 EE---KMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQEEK---IR 447
E +M E+E++ EQ ++ +E E++ E E ++Q Q A+ Q + E+E K R
Sbjct: 1338 SETLRRMEEEERLAEQ-QRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1396
Query: 448 EQEKKMWRQEEKIHEQEK---IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
QE+ + R+E + Q++ I+EE ++ Q + K + E R + ++ E+
Sbjct: 1397 MQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1456
Query: 505 IRKQEEKVWRQE-------EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557
+R Q E RQ + +R + E+ Q+ + + E++R Q + + ++ E E
Sbjct: 1457 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1516
Query: 558 ---KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
++ E + ++ + + E++R Q E+ E ++R+ E +R Q + + ++
Sbjct: 1517 LASRVKAEAEAAREKQRALQALEELRLQAEEA---ERRLRQAEVERARQVQVALETAQRS 1573
Query: 615 REQE--EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
E E K EK + E ++E+ + E+ + ++ E E +E E + R
Sbjct: 1574 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1633
Query: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
+ K E ++R Q E++ +Q+ + Q + EK E+ E+ + K +EQ + R E+
Sbjct: 1634 WQLKANE-ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1692
Query: 733 MWEQEVRLRQ 742
E++ +L +
Sbjct: 1693 ELEKQRQLAE 1702
Score = 99.0 bits (245), Expect = 1e-20
Identities = 169/801 (21%), Positives = 328/801 (40%), Gaps = 118/801 (14%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P P HPM + + + ++T H VG A K ++G+ +
Sbjct: 796 PRHPAHPMRGRLPLLAVCDYKQVEVTVHKGDECQLVGPAQPSHWKVLSSSGSEAAVPSVC 855
Query: 103 GCHSPEDEQ--------KASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVK 154
P +++ +A HQ L +L + ++ + ++Q+ +S +
Sbjct: 856 FLVPPPNQEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFR 915
Query: 155 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE--LTKERDALSLELYRN 212
L+ E + LH LE A + A + E L ER+ S +
Sbjct: 916 TLKPEEQR--QALHS-------LELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQ 966
Query: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--------------ERAKLLL 258
+ E+ A+ + + Q SE +I+L ++ + + E A+ +
Sbjct: 967 QLLQS--LEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIA 1024
Query: 259 PQQQLQAEADHLGKELQSVSA---KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315
QQ+ QAE + LGK + +SA K+ A E + L + E + + E+ ++
Sbjct: 1025 EQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ-VRSLSAI 1083
Query: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--EKMRRQEEMMW 373
E+ + I + EE +R EE + E + E+ K +K+R Q E
Sbjct: 1084 YLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQ 1143
Query: 374 EKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQEEKRQE--EEKIREQEKRQEQEA 430
+ +R + E E++++ E+ E E+ RE+ + E + + + + RQ +
Sbjct: 1144 PTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELE 1203
Query: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIH-----EQEKIREEEKRQEQ---EEMWRQE 482
++ RQ RE + + + R++E+I + + +R E+ RQEQ EE+ R
Sbjct: 1204 QLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVR-EQLRQEQALLEEIERHG 1262
Query: 483 EKIHEQEEIWRQ---------------KEKMH-----EQEEKIRKQEEKVWRQ------- 515
EK+ E + +Q K ++ ++ K++ E V ++
Sbjct: 1263 EKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTH 1322
Query: 516 ---------------EEKIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQE 557
E +R EE+ R E++ + E++ E E E R+ + H Q
Sbjct: 1323 YSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA 1382
Query: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
K E + +E + +M QEE +R +E V Q++K QEE +Q ++ + + K R+
Sbjct: 1383 KAQAEREAKELQQRM--QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1440
Query: 618 EE------KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
E +I+E+ +R Q E Q + + + + + E+ Q+ + QE+ E +
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1500
Query: 672 R--QEEKIREQE------KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
R Q+E R+++ +++ + E RE++ +Q EE + E E E ++++ E
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE----EAERRLRQAE 1556
Query: 724 EKMRRQEEKMWEQEVRLRQQE 744
+ RQ + E R + E
Sbjct: 1557 VERARQVQVALETAQRSAEAE 1577
Score = 70.9 bits (172), Expect = 4e-12
Identities = 76/326 (23%), Positives = 159/326 (48%), Gaps = 45/326 (13%)
Query: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
Q + + L+ ++ ++ T K E ++ ++Q + A++ RL +
Sbjct: 2303 QQRALAEKMLKEKMQAVQEATRLKAEAEL--------LQQQKELAQEQARRLQE------ 2348
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
+ EQ +A + + R +E + + +S E R + E+ A+ +E Q
Sbjct: 2349 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2408
Query: 236 EKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
+ EI +L+ EL + E+ L+ + + ++DH + L+ A+L+ + E+ + +
Sbjct: 2409 QAEEIGEKLHRTELATQ-EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2467
Query: 294 LNQQQEEKMW--RQEEKIQEWEEKIQE---------QEEKIREQEEKIREQ--EEKMRRQ 340
L Q + E+M +QE+ +QE + Q Q E+ EQE+ EQ ++++ +
Sbjct: 2468 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2527
Query: 341 EEMMWEKEEKMRRQEEMMWEK-------EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
+++ +EE+ R+Q++M E+ EE RRQ E EE +RR++E + + E++
Sbjct: 2528 QQL---REEQQRQQQQMEQERQRLVASMEEARRRQH----EAEEGVRRKQEELQQLEQQR 2580
Query: 394 RELEEKM-HEQEKIREQEEKRQEEEK 418
R+ EE + E +++REQ + +E+ +
Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHR 2606
Score = 51.2 bits (121), Expect = 3e-06
Identities = 100/538 (18%), Positives = 217/538 (40%), Gaps = 80/538 (14%)
Query: 272 KELQSVSAKLQAQVEEN-ELWNRLNQQQE-----EKMWRQEEKIQEWE----EKIQEQEE 321
+E Q +L+AQ + LW++L+ + + + R + I+ W ++ +E+
Sbjct: 863 QEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQ 922
Query: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 381
+ ++ Q Q+ + E+++ + E + + + +E+ R
Sbjct: 923 RQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRC 982
Query: 382 QEEMMWEKEEKIRELE----EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Q + K+ ++ +LE +H ++E R+ ++I EQ+K Q + + +
Sbjct: 983 QRCISELKDIRL-QLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVA 1041
Query: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
++ + EK+ + R E E + E++ I+ +K K
Sbjct: 1042 RLSAEAEKVLALP------------EPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLK 1089
Query: 498 M--------HEQEEKIRKQEEKVWRQE---------EKIREQEEKIREQEEKMWRQEEKI 540
EE +R EE++ + E + +K+R Q E + +
Sbjct: 1090 TISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDAL 1149
Query: 541 REQ----EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ 596
R++ +E+ ++ H + + E E+ +E+ ++ + + + Q + R+ E++ Q
Sbjct: 1150 RDELRGAQEVGERLQQRHGERDV-EVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1208
Query: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQ----EEKIREQEEKIREQEEMTQEQEEKMGEQ 652
+E + + + R ++E+IQ + +REQ QE+ E+ E+ GE+
Sbjct: 1209 LRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ----LRQEQALLEEIERHGEK 1264
Query: 653 EEKMCEQEEKM--------QEQEETMWRQEEKIREQEKKIREQ---EEKIREQEEMMQEQ 701
E+ C++ K + Q T Q E + KK + Q E I+E ++
Sbjct: 1265 VEE-CQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHY 1323
Query: 702 EE---------KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
E K + + E+EE++ EQ+ R E++ E E L +Q + + H
Sbjct: 1324 SELTTLTSQYIKFISETLRRMEEEERLAEQQRAEER--ERLAEVEAALEKQRQLAEAH 1379
Score = 30.4 bits (67), Expect = 6.3
Identities = 35/200 (17%), Positives = 84/200 (42%), Gaps = 9/200 (4%)
Query: 62 EAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQ--KASHQHQE 119
E + Q +DH + A + +K+K+ S + + EQ + + Q+
Sbjct: 2435 EIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2493
Query: 120 ALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQ 179
+ E ++ + R + +K +L+ +QL E + ++ E ++
Sbjct: 2494 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ------ERQR 2547
Query: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
++++ +++ E + ++++ L + +E L E+N +L+E+LQL+E +
Sbjct: 2548 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2607
Query: 240 IQLNVKELKRKLERAKLLLP 259
+ +E+ A LP
Sbjct: 2608 ALAHSEEVTASQVAATKTLP 2627
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 150 bits (380), Expect = 3e-36
Identities = 159/700 (22%), Positives = 337/700 (48%), Gaps = 89/700 (12%)
Query: 112 KASHQHQEALRRELEAQVHTIR------ILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
KAS + A + ELE ++ IR + + ++ EL+ A + + E R+
Sbjct: 1899 KASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAAR--QRQLAAEEERRRREAEE 1956
Query: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
R+ S E + A + ++ +EE + R+ E R +E +K +
Sbjct: 1957 RVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ 2016
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
+EK ++ E +EL++ L++ + +L Q + +AEA E ++ A++QA+
Sbjct: 2017 AEEKAHAFAVQQKE-----QELQQTLQQEQSVLDQLRGEAEAARRAAE-EAEEARVQAER 2070
Query: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
E + +R ++ E++ + E+ + + Q EK+R++ E +E RR +
Sbjct: 2071 EAAQ--SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAE-----QEAARRAQAEQA 2123
Query: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
+K EM EK +K E+ +R++ ++ E +LEE H++
Sbjct: 2124 ALRQKQAADAEM--EKHKKFA---------EQTLRQKAQVEQELTTLRLQLEETDHQKNL 2172
Query: 406 IREQEEKRQEE--EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
+ E+ ++ + E E R++ + +E+ + Q E++ + + +I E E + +K + Q
Sbjct: 2173 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI-EAENRALILRDKDNTQ 2231
Query: 464 EKIREEEKRQEQ--EEMWR--------------QEEKIHEQEEIWRQ--KEKMHEQEE-- 503
++EE ++ +Q EE R EE + +Q + + KEKM +E
Sbjct: 2232 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2291
Query: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
+++ + E + +Q+E +EQ +++E +E+M +Q + + + E E+ + E E E
Sbjct: 2292 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2351
Query: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ--EQEEKMWKQEEKIREQE--- 618
+ + + +M R + + E ++ +Q E+I E+ + + QE+ Q +I+ Q+
Sbjct: 2352 RLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH 2411
Query: 619 --EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE-QEEKMCEQEEKMQEQ---EETMWR 672
E+++E ++ ++EK++++ ++ Q + E+M Q+E++ ++ + +Q+ E+
Sbjct: 2412 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2471
Query: 673 QEEKIREQEKKIREQ-------------EEKIREQEEMMQEQEE----------KMWEQE 709
Q E+ EQEK EQ EE+ R+Q++M QE++ + E E
Sbjct: 2472 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2531
Query: 710 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
E + ++E++Q+ E++ R+QEE + E+ RLR+Q + ++E
Sbjct: 2532 EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEE 2571
Score = 137 bits (344), Expect = 5e-32
Identities = 153/673 (22%), Positives = 306/673 (45%), Gaps = 66/673 (9%)
Query: 106 SPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
SP + K + ++ ++ + H + T ++ + ++++E E R
Sbjct: 1266 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIK----FISETLRRMEEEERLAEQ 1321
Query: 166 RLHDSWKFAGELEQALS-------AVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
+ + + E+E AL A A K +A+R +EL + + E+ R +
Sbjct: 1322 QRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVD 1378
Query: 219 LKEKNAKLQEKLQ-LVESEKSEIQLNVKELKRKLERAKLLLPQQ----QLQAEADHLGK- 272
+++ +QE+LQ L +S ++EIQ ++ + ER++L + ++ +LQ EA +
Sbjct: 1379 AQQQKRSIQEELQQLRQSSEAEIQAKARQAEAA-ERSRLRIEEEIRVVRLQLEATERQRG 1437
Query: 273 ----ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
ELQ+ L+A+ EE E R Q++ E++ RQ +Q++ ++ R+ E
Sbjct: 1438 GAEGELQA----LRARAEEAEAQKRQAQEEAERLRRQ----------VQDESQRKRQAEV 1483
Query: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
++ +++ + E EK+ ++ EE+ + EE RR + E+ +++ E
Sbjct: 1484 ELAS---RVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1540
Query: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
E EL+ K + Q E+ +EE + + R+E E + +Q E R +EE RE
Sbjct: 1541 SAEA--ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERE 1598
Query: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ 508
E R + K +E ++R + + Q++ Q E ++EE R+ + + EE+ +Q
Sbjct: 1599 LE----RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ 1654
Query: 509 EEKVWRQEEKIRE------QEEKIREQEEKMWRQEEKIREQEEMWREEEKMH-EQEKIWE 561
E ++ EK R+ Q+ EQE R E + EQ+ EEE ++E
Sbjct: 1655 RELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAA 1714
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE-------KMWKQEEKI 614
+KRQE E ++ + ++ R EE+ R EK +++ E ++ ++ ++
Sbjct: 1715 TQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL 1774
Query: 615 REQEEKIQEQEEKIREQEEKIR-EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
R E+ + Q + E + R E E + E+ +GE E E ++E+E R
Sbjct: 1775 RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1834
Query: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
++ + R EE+ + + ++E+ ++ + + E+++ + E + RRQ E
Sbjct: 1835 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVE-- 1892
Query: 734 WEQEVRLRQQEEK 746
E+ + L+ EK
Sbjct: 1893 -EEILALKASFEK 1904
Score = 135 bits (339), Expect = 2e-31
Identities = 149/659 (22%), Positives = 301/659 (45%), Gaps = 42/659 (6%)
Query: 106 SPEDEQKASHQHQEALRRE---LEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
S E E +A + EA R +E ++ +R L + TE Q ++ ++ L A +
Sbjct: 1396 SSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRG--GAEGELQALRARAEE 1452
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
++ + + A L + + + +K++A+ + K + E R EEL+ +
Sbjct: 1453 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1512
Query: 223 NAKLQEKLQLVESEKS-EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
+ + +L+ E E++ ++Q+ ++ +R E A+L + + L + LQ +
Sbjct: 1513 AEEAERRLRQAEVERARQVQVALETAQRSAE-AELQSKRASFAEKTAQLERSLQEEHVAV 1571
Query: 282 QAQVEENELWNRLNQQQEEKMWRQE--EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
EE E R QQ E + R+E +++ W+ K E ++R Q E++ +Q+ +
Sbjct: 1572 AQLREEAE--RRAQQQAEAERAREEAERELERWQLKANEAL-RLRLQAEEVAQQKSLAQA 1628
Query: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR------QEEMMWEKEE-K 392
+ E +++E+ R+ + EE+ RQ E+ ++ EK R+ Q+ + E+E +
Sbjct: 1629 EAE---KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR 1685
Query: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
+R E+ +Q ++ E+E R + E +KRQE EA++ K+R + E + + +
Sbjct: 1686 LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL----AKVRAEMEVLLASKAR 1741
Query: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEK 511
+ E+ K R E + E+ + ++ EE RQ++ E + R + E+
Sbjct: 1742 AEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAER 1801
Query: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
V EK+ E R + E +EK E E + R E Q + EE+ Q + D
Sbjct: 1802 VLA--EKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADI 1859
Query: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE---EKIREQEEKIQEQEEKI 628
R + + + ++ RQ+ + + +R++ EE++ + EK + +++ + +I
Sbjct: 1860 EERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRI 1919
Query: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ---EEKIREQEKKIR 685
R E +E + E + Q + E+E + +E EE + + EE+ Q K
Sbjct: 1920 RSNAEDTLRSKE---QAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL 1976
Query: 686 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
E+ E+++ + E + E+ E++ Q + QE +K + EEK V+ ++QE
Sbjct: 1977 EEVERLKAKVEEARRLRER---AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2032
Score = 134 bits (337), Expect = 3e-31
Identities = 145/687 (21%), Positives = 322/687 (46%), Gaps = 74/687 (10%)
Query: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ-HAVKQLEGEARDLISRL 167
+EQ A H + ++E ++ +R + + E Q L +Q+E E L +
Sbjct: 1849 EEQAAQH------KADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASF 1902
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ ELE L + + + R +KE+ L R +EE + + A+ +
Sbjct: 1903 EKAAAGKAELELELGRIRSNAEDTLR-----SKEQAELEAARQRQLAAEEERRRREAEER 1957
Query: 228 EKLQLVESEKSEIQLN-----VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282
+ L E++ Q V+ LK K+E A+ L + + Q A L ++ +LQ
Sbjct: 1958 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE-QESARQLQLAQEAAQKRLQ 2016
Query: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
A+ + + + +Q+ ++ +QE+ + + E + E+ E+ R Q E+ Q
Sbjct: 2017 AEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR 2076
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 402
E+ E++++ E ++ + R Q + EK K QE + E+ L +K
Sbjct: 2077 RQVEEAERLKQSAE----EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAA-LRQK--- 2128
Query: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE--EKI 460
Q E E+ ++ E+ Q+ + EQE R + + + ++ + ++E + + E E
Sbjct: 2129 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2188
Query: 461 HEQEKIREE--EKRQEQEEMWRQEEKIHEQEE--IWRQKEK----MHEQEEKIRKQEEKV 512
++ ++ EE R + EE+ + + +I + I R K+ + E+ EK+++ E+
Sbjct: 2189 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2248
Query: 513 WRQEEKIREQ-------EEKIREQE---EKMWRQE-EKIREQEEMWREEEKMHEQEKIWE 561
R +E EE + +Q EKM +++ + ++E + E E + +Q+++ +
Sbjct: 2249 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ 2308
Query: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
E+ R+ QEDK + +++ E+ + R E R+++ + + E++ + ++ + +
Sbjct: 2309 EQARRLQEDKE-QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2367
Query: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
+E ++ R+Q E+I E+ T+ + QE+ Q ++Q Q+ E++RE
Sbjct: 2368 EEDAQRFRKQAEEIGEKLHRTE-----LATQEKVTLVQTLEIQRQQSD--HDAERLREAI 2420
Query: 682 KKIREQEEKIREQEEMMQ-EQEEKMWEQEEKMCEQEEKMQE----------QEEKMRRQE 730
++ ++EK++++ +++Q + EE Q+E++ ++ + +Q+ Q E+ QE
Sbjct: 2421 AELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQE 2480
Query: 731 ----EKMWEQEV----RLRQQEEKMQE 749
E++++ EV +LR+++++ Q+
Sbjct: 2481 KAKLEQLFQDEVAKAQQLREEQQRQQQ 2507
Score = 132 bits (332), Expect = 1e-30
Identities = 185/781 (23%), Positives = 349/781 (44%), Gaps = 132/781 (16%)
Query: 66 QLTDHHPQTNPSVGTAASDTKKKKINNGTNP-------------ETTT---------SGG 103
QL + Q P AS KK K+ +G+ E TT S
Sbjct: 1253 QLVTYKAQLEP----VASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISET 1308
Query: 104 CHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDL 163
E+E++ + Q Q A RE A+V + + Q+A ++Q A Q E EA++L
Sbjct: 1309 LRRMEEEERLAEQ-QRAEERERLAEVEA-----ALEKQRQLAEAHAQ-AKAQAEREAKEL 1361
Query: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
R+ + + + +AV Q++K EEL + R + E+ E +
Sbjct: 1362 QQRMQEE-----VVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSR 1415
Query: 224 AKLQEKLQLV-------ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
+++E++++V E ++ + ++ L+ + E A+ ++Q Q EA+ L +++Q
Sbjct: 1416 LRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA--QKRQAQEEAERLRRQVQD 1473
Query: 277 VSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
S K QA+VE L +R+ + E R++++ + E+++ Q E E E ++R+ E
Sbjct: 1474 ESQRKRQAEVE---LASRVKAEAEAA--REKQRALQALEELRLQAE---EAERRLRQAEV 1525
Query: 336 KMRRQEEMMWEK-----EEKMRRQEEMMWEKEEKMRR--QEE------MMWEKEEKMRRQ 382
+ RQ ++ E E +++ + EK ++ R QEE + E E + ++Q
Sbjct: 1526 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQ 1585
Query: 383 EEMMWEKEEKIRELE----------------EKMHEQEKIREQEEKRQEEEKIREQEKRQ 426
E +EE RELE E++ +Q+ + + E ++Q+EE RE +R
Sbjct: 1586 AEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG 1645
Query: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE--KIREEEKRQEQEEMWRQEEK 484
+ E + RQ E + EQE + + Q + Q+ EQE ++R E ++ EQ+ +EE
Sbjct: 1646 KAEEQAVRQRE-LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1704
Query: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVW-------RQEEKIREQEEKIREQ-EEKMWRQ 536
Q E +K E E ++ K ++ R EE+ R EK +++ E + R
Sbjct: 1705 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1764
Query: 537 EEKIREQEEMWREEEKMHEQEKIWEEE---KRQEQE----DKMWRQEEKIREQEEKVWRQ 589
E E + E+ Q ++ EE+ +R E E +K+ E R + E
Sbjct: 1765 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1824
Query: 590 EEKIREQEEKRQEQEEKMWKQ---EEKIREQEEKIQEQEEKIREQ------------EEK 634
+EK E E R+ E++ +++ EE+ + + I+E+ ++R+ E+
Sbjct: 1825 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1884
Query: 635 IREQEEMTQE-------QEEKMGEQEEKMCEQEEKMQEQEETMWRQEE---KIREQEKKI 684
+R++ ++ +E E+ + E E E+T+ +E+ + Q +
Sbjct: 1885 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1944
Query: 685 REQEEKIREQEEMMQEQ---EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
E+E + RE EE +Q+ EE+ Q + E+ E+++ + E+ RR E+ ++ R
Sbjct: 1945 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2004
Query: 742 Q 742
Q
Sbjct: 2005 Q 2005
Score = 131 bits (329), Expect = 3e-30
Identities = 166/736 (22%), Positives = 323/736 (43%), Gaps = 83/736 (11%)
Query: 54 ETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKA 113
+ RQ +L + QL + +P +G D ++++ P D Q
Sbjct: 1164 DVRQRELEQLGRQLRYYRESADP-LGAWLQDARRRQEQIQAMPLA----------DSQAV 1212
Query: 114 SHQ--HQEALRRELEAQVHTIRILTCQKT-----------ELQMALYYSQHAVKQLEGEA 160
Q ++AL E+E H ++ CQ+ ELQ+ Y +Q +
Sbjct: 1213 REQLRQEQALLEEIER--HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKK 1270
Query: 161 RDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE-LTKERDALSLELYRNTITDEEL 219
+ S + +L S + T + ++I E L + + L + E L
Sbjct: 1271 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERL 1330
Query: 220 KEKNAKLQEKLQLVESE---KSEIQLNVKELKRKLERAKL------LLPQQQLQAEADHL 270
E A L+++ QL E+ K++ + KEL+++++ + + QQQ ++ + L
Sbjct: 1331 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1390
Query: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
+ QS A++QA+ + E R + EE++ ++ E + Q + + +
Sbjct: 1391 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEI----RVVRLQLEATERQRGGAEGELQAL 1446
Query: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
R + E+ Q+ E+ E++RRQ + E + +RQ E+ E +++ + E EK+
Sbjct: 1447 RARAEEAEAQKRQAQEEAERLRRQVQ----DESQRKRQAEV--ELASRVKAEAEAAREKQ 1500
Query: 391 EKIRELEEKMHEQE----KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
++ LEE + E ++R+ E +R + ++ + ++ EA++ + K EK
Sbjct: 1501 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKT 1557
Query: 447 REQEKKMWRQEEKIHEQEKIREEEKR-QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
+ E+ + QEE + + E E+R Q+Q E R E+ + E W+ K + ++
Sbjct: 1558 AQLERSL--QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKAN---EALRL 1612
Query: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE--EEKMHEQEKIWEEE 563
R Q E+V +Q+ + + EK +E+ E+ R+ K EQ RE E+++ +Q ++ E
Sbjct: 1613 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1672
Query: 564 KRQ----EQEDKMWRQEEKIREQ-----EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
+Q EQE R E + EQ EE++ R + + +KRQE E ++ K+
Sbjct: 1673 AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL----AKV 1728
Query: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
R + E + K R +EE E+ Q E + G E + E+ +++ E RQ
Sbjct: 1729 RAEMEVLLAS--KARAEEESRSTSEKSKQRLEAEAGRFRE-LAEEAARLRALAEEAKRQR 1785
Query: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
+ E + R + E++ + E+ + E E E ++E+E + R
Sbjct: 1786 QLAEEDAARQRAEAERV------LAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1839
Query: 735 EQEVRLRQQEEKMQEH 750
++ + R+ EE+ +H
Sbjct: 1840 DEAFQRRRLEEQAAQH 1855
Score = 115 bits (288), Expect = 1e-25
Identities = 152/734 (20%), Positives = 329/734 (44%), Gaps = 108/734 (14%)
Query: 119 EALRRELEAQVHTIRILTCQKT-ELQMALYYSQHAVKQLEGEA-------------RDLI 164
E +R EA++ + R +KT +L+ +L AV QL EA R+
Sbjct: 1536 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1595
Query: 165 SRLHDSWKF-----------AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT 213
R + W+ A E+ Q S + +K E + R + R
Sbjct: 1596 ERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR 1655
Query: 214 ITDEELKEKNAKLQEKL--QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
E+ EK +L E Q + +E+ I+L + + + +R L +LQ EA
Sbjct: 1656 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1715
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
++ Q + A+L E E+ + EE+ EK ++ E + ++ E+ ++R
Sbjct: 1716 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1775
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-------EKMRRQEEM-MWEKE---EKMR 380
E+ +RQ ++ E + R + E + ++ +++ + E+ + EKE E++R
Sbjct: 1776 ALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR 1835
Query: 381 RQEEMMWEKEEKIRE--------LEEKMHEQEKIREQEEKRQE---EEKIREQEKRQEQ- 428
R E + ++ E +EE++ + K + E +RQ+ E+ +R++ + +E+
Sbjct: 1836 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 1895
Query: 429 -------------EAKMWRQEEKIREQ-EEKIREQEK---KMWRQEEKIHEQEKIREEEK 471
+A++ + +IR E+ +R +E+ + RQ + E+E+ R E +
Sbjct: 1896 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1955
Query: 472 RQEQEEMWRQEEKIHEQ----EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
+ Q+ + +EE ++ EE+ R K K+ E + E++ RQ + +E +K
Sbjct: 1956 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2015
Query: 528 EQEEKM--WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ--EQEDKMWRQEEKIREQE 583
+ EEK + ++K +E ++ ++E+ + +Q + E R+ E+ ++ Q E+ Q
Sbjct: 2016 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2075
Query: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR---EQEEKIQEQEEK--IREQ------- 631
+ + E++++ E++ + + EK+R EQE + Q E+ +R++
Sbjct: 2076 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2135
Query: 632 -------EEKIREQEEMTQE------QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
E+ +R++ ++ QE Q E+ Q+ + E+ ++++ + RQ ++
Sbjct: 2136 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVE 2195
Query: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK------ 732
E+ +R Q E++ + + ++ + + +++ + +QE+ EKM++ E+
Sbjct: 2196 EELFSVRVQMEELSKLKARIEAENRALILRDKD--NTQRFLQEEAEKMKQVAEEAARLSV 2253
Query: 733 MWEQEVRLRQQEEK 746
++ RLRQ E+
Sbjct: 2254 AAQEAARLRQLAEE 2267
Score = 114 bits (285), Expect = 3e-25
Identities = 120/550 (21%), Positives = 251/550 (45%), Gaps = 46/550 (8%)
Query: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
E +E+ A+L E+ Q V ++ Q +++L R+L + + AD LG LQ
Sbjct: 1143 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQL---------RYYRESADPLGAWLQD 1193
Query: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
+ Q Q++ L + Q + RQE+ + E +I+ EK+ E + ++
Sbjct: 1194 ARRR-QEQIQAMPL---ADSQAVREQLRQEQALLE---EIERHGEKVEECQRFAKQYINA 1246
Query: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
++ E + + ++ +K + E ++ E + E+ + I+ +
Sbjct: 1247 IKDYELQLVTYKAQLEPVASPA-KKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFI 1305
Query: 397 EE---KMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQEEK---IR 447
E +M E+E++ EQ ++ +E E++ E E ++Q Q A+ Q + E+E K R
Sbjct: 1306 SETLRRMEEEERLAEQ-QRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1364
Query: 448 EQEKKMWRQEEKIHEQEK---IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
QE+ + R+E + Q++ I+EE ++ Q + K + E R + ++ E+
Sbjct: 1365 MQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1424
Query: 505 IRKQEEKVWRQE-------EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557
+R Q E RQ + +R + E+ Q+ + + E++R Q + + ++ E E
Sbjct: 1425 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1484
Query: 558 ---KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
++ E + ++ + + E++R Q E+ E ++R+ E +R Q + + ++
Sbjct: 1485 LASRVKAEAEAAREKQRALQALEELRLQAEEA---ERRLRQAEVERARQVQVALETAQRS 1541
Query: 615 REQE--EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
E E K EK + E ++E+ + E+ + ++ E E +E E + R
Sbjct: 1542 AEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELER 1601
Query: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
+ K E ++R Q E++ +Q+ + Q + EK E+ E+ + K +EQ + R E+
Sbjct: 1602 WQLKANE-ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1660
Query: 733 MWEQEVRLRQ 742
E++ +L +
Sbjct: 1661 ELEKQRQLAE 1670
Score = 99.0 bits (245), Expect = 1e-20
Identities = 169/801 (21%), Positives = 328/801 (40%), Gaps = 118/801 (14%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P P HPM + + + ++T H VG A K ++G+ +
Sbjct: 764 PRHPAHPMRGRLPLLAVCDYKQVEVTVHKGDECQLVGPAQPSHWKVLSSSGSEAAVPSVC 823
Query: 103 GCHSPEDEQ--------KASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVK 154
P +++ +A HQ L +L + ++ + ++Q+ +S +
Sbjct: 824 FLVPPPNQEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFR 883
Query: 155 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEE--LTKERDALSLELYRN 212
L+ E + LH LE A + A + E L ER+ S +
Sbjct: 884 TLKPEEQR--QALHS-------LELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQ 934
Query: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL--------------ERAKLLL 258
+ E+ A+ + + Q SE +I+L ++ + + E A+ +
Sbjct: 935 QLLQS--LEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIA 992
Query: 259 PQQQLQAEADHLGKELQSVSA---KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315
QQ+ QAE + LGK + +SA K+ A E + L + E + + E+ ++
Sbjct: 993 EQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ-VRSLSAI 1051
Query: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--EKMRRQEEMMW 373
E+ + I + EE +R EE + E + E+ K +K+R Q E
Sbjct: 1052 YLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQ 1111
Query: 374 EKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQEEKRQE--EEKIREQEKRQEQEA 430
+ +R + E E++++ E+ E E+ RE+ + E + + + + RQ +
Sbjct: 1112 PTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELE 1171
Query: 431 KMWRQEEKIREQEEKIREQEKKMWRQEEKIH-----EQEKIREEEKRQEQ---EEMWRQE 482
++ RQ RE + + + R++E+I + + +R E+ RQEQ EE+ R
Sbjct: 1172 QLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVR-EQLRQEQALLEEIERHG 1230
Query: 483 EKIHEQEEIWRQ---------------KEKMH-----EQEEKIRKQEEKVWRQ------- 515
EK+ E + +Q K ++ ++ K++ E V ++
Sbjct: 1231 EKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTH 1290
Query: 516 ---------------EEKIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQE 557
E +R EE+ R E++ + E++ E E E R+ + H Q
Sbjct: 1291 YSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA 1350
Query: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
K E + +E + +M QEE +R +E V Q++K QEE +Q ++ + + K R+
Sbjct: 1351 KAQAEREAKELQQRM--QEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1408
Query: 618 EE------KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
E +I+E+ +R Q E Q + + + + + E+ Q+ + QE+ E +
Sbjct: 1409 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1468
Query: 672 R--QEEKIREQE------KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
R Q+E R+++ +++ + E RE++ +Q EE + E E E ++++ E
Sbjct: 1469 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAE----EAERRLRQAE 1524
Query: 724 EKMRRQEEKMWEQEVRLRQQE 744
+ RQ + E R + E
Sbjct: 1525 VERARQVQVALETAQRSAEAE 1545
Score = 70.9 bits (172), Expect = 4e-12
Identities = 76/326 (23%), Positives = 159/326 (48%), Gaps = 45/326 (13%)
Query: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
Q + + L+ ++ ++ T K E ++ ++Q + A++ RL +
Sbjct: 2271 QQRALAEKMLKEKMQAVQEATRLKAEAEL--------LQQQKELAQEQARRLQE------ 2316
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
+ EQ +A + + R +E + + +S E R + E+ A+ +E Q
Sbjct: 2317 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2376
Query: 236 EKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 293
+ EI +L+ EL + E+ L+ + + ++DH + L+ A+L+ + E+ + +
Sbjct: 2377 QAEEIGEKLHRTELATQ-EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2435
Query: 294 LNQQQEEKMW--RQEEKIQEWEEKIQE---------QEEKIREQEEKIREQ--EEKMRRQ 340
L Q + E+M +QE+ +QE + Q Q E+ EQE+ EQ ++++ +
Sbjct: 2436 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2495
Query: 341 EEMMWEKEEKMRRQEEMMWEK-------EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 393
+++ +EE+ R+Q++M E+ EE RRQ E EE +RR++E + + E++
Sbjct: 2496 QQL---REEQQRQQQQMEQERQRLVASMEEARRRQH----EAEEGVRRKQEELQQLEQQR 2548
Query: 394 RELEEKM-HEQEKIREQEEKRQEEEK 418
R+ EE + E +++REQ + +E+ +
Sbjct: 2549 RQQEELLAEENQRLREQLQLLEEQHR 2574
Score = 51.2 bits (121), Expect = 3e-06
Identities = 100/538 (18%), Positives = 217/538 (40%), Gaps = 80/538 (14%)
Query: 272 KELQSVSAKLQAQVEEN-ELWNRLNQQQE-----EKMWRQEEKIQEWE----EKIQEQEE 321
+E Q +L+AQ + LW++L+ + + + R + I+ W ++ +E+
Sbjct: 831 QEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQ 890
Query: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 381
+ ++ Q Q+ + E+++ + E + + + +E+ R
Sbjct: 891 RQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRC 950
Query: 382 QEEMMWEKEEKIRELE----EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Q + K+ ++ +LE +H ++E R+ ++I EQ+K Q + + +
Sbjct: 951 QRCISELKDIRL-QLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVA 1009
Query: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
++ + EK+ + R E E + E++ I+ +K K
Sbjct: 1010 RLSAEAEKVLALP------------EPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLK 1057
Query: 498 M--------HEQEEKIRKQEEKVWRQE---------EKIREQEEKIREQEEKMWRQEEKI 540
EE +R EE++ + E + +K+R Q E + +
Sbjct: 1058 TISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDAL 1117
Query: 541 REQ----EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ 596
R++ +E+ ++ H + + E E+ +E+ ++ + + + Q + R+ E++ Q
Sbjct: 1118 RDELRGAQEVGERLQQRHGERDV-EVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1176
Query: 597 EEKRQEQEEKMWKQEEKIREQEEKIQEQ----EEKIREQEEKIREQEEMTQEQEEKMGEQ 652
+E + + + R ++E+IQ + +REQ QE+ E+ E+ GE+
Sbjct: 1177 LRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ----LRQEQALLEEIERHGEK 1232
Query: 653 EEKMCEQEEKM--------QEQEETMWRQEEKIREQEKKIREQ---EEKIREQEEMMQEQ 701
E+ C++ K + Q T Q E + KK + Q E I+E ++
Sbjct: 1233 VEE-CQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHY 1291
Query: 702 EE---------KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
E K + + E+EE++ EQ+ R E++ E E L +Q + + H
Sbjct: 1292 SELTTLTSQYIKFISETLRRMEEEERLAEQQRAEER--ERLAEVEAALEKQRQLAEAH 1347
Score = 30.4 bits (67), Expect = 6.3
Identities = 35/200 (17%), Positives = 84/200 (42%), Gaps = 9/200 (4%)
Query: 62 EAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQ--KASHQHQE 119
E + Q +DH + A + +K+K+ S + + EQ + + Q+
Sbjct: 2403 EIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQ 2461
Query: 120 ALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQ 179
+ E ++ + R + +K +L+ +QL E + ++ E ++
Sbjct: 2462 SFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQ------ERQR 2515
Query: 180 ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSE 239
++++ +++ E + ++++ L + +E L E+N +L+E+LQL+E +
Sbjct: 2516 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2575
Query: 240 IQLNVKELKRKLERAKLLLP 259
+ +E+ A LP
Sbjct: 2576 ALAHSEEVTASQVAATKTLP 2595
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.121 0.331
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,361,254
Number of Sequences: 37866
Number of extensions: 2461068
Number of successful extensions: 272957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1978
Number of HSP's successfully gapped in prelim test: 1262
Number of HSP's that attempted gapping in prelim test: 20660
Number of HSP's gapped (non-prelim): 57706
length of query: 750
length of database: 18,247,518
effective HSP length: 110
effective length of query: 640
effective length of database: 14,082,258
effective search space: 9012645120
effective search space used: 9012645120
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.