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Search of human proteins with 222418565
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222418565 hypothetical protein LOC728591 isoform a [Homo
sapiens]
(214 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222418565 hypothetical protein LOC728591 isoform a [Homo sapi... 422 e-118
gi|222418576 hypothetical protein LOC728591 isoform d [Homo sapi... 224 6e-59
gi|222418574 hypothetical protein LOC728591 isoform d [Homo sapi... 224 6e-59
gi|222418570 hypothetical protein LOC728591 isoform b [Homo sapi... 157 8e-39
gi|222418567 hypothetical protein LOC728591 isoform b [Homo sapi... 157 8e-39
gi|222418572 hypothetical protein LOC728591 isoform c [Homo sapi... 150 6e-37
gi|55749708 outer dense fiber of sperm tails 2-like isoform b [H... 52 5e-07
gi|55749696 outer dense fiber of sperm tails 2-like isoform a [H... 52 5e-07
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 49 2e-06
gi|148746195 trichohyalin [Homo sapiens] 49 4e-06
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 47 9e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 47 2e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 47 2e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 47 2e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 45 4e-05
gi|38044112 restin isoform b [Homo sapiens] 45 6e-05
gi|4506751 restin isoform a [Homo sapiens] 45 6e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 44 1e-04
gi|156104908 myosin heavy chain 6 [Homo sapiens] 44 1e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 44 1e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 43 2e-04
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 43 2e-04
gi|134152674 rabaptin, RAB GTPase binding effector protein 1 iso... 43 2e-04
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof... 43 2e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 42 3e-04
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 42 3e-04
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 42 3e-04
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 42 3e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 42 4e-04
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 42 4e-04
>gi|222418565 hypothetical protein LOC728591 isoform a [Homo
sapiens]
Length = 214
Score = 422 bits (1085), Expect = e-118
Identities = 214/214 (100%), Positives = 214/214 (100%)
Query: 1 MKEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKT 60
MKEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKT
Sbjct: 1 MKEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKT 60
Query: 61 RYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
RYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK
Sbjct: 61 RYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLV 180
TLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLV
Sbjct: 121 TLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLV 180
Query: 181 KTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP 214
KTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP
Sbjct: 181 KTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP 214
>gi|222418576 hypothetical protein LOC728591 isoform d [Homo
sapiens]
Length = 112
Score = 224 bits (570), Expect = 6e-59
Identities = 112/112 (100%), Positives = 112/112 (100%)
Query: 103 MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ 162
MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ
Sbjct: 1 MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ 60
Query: 163 VSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP 214
VSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP
Sbjct: 61 VSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP 112
>gi|222418574 hypothetical protein LOC728591 isoform d [Homo
sapiens]
Length = 112
Score = 224 bits (570), Expect = 6e-59
Identities = 112/112 (100%), Positives = 112/112 (100%)
Query: 103 MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ 162
MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ
Sbjct: 1 MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ 60
Query: 163 VSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP 214
VSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP
Sbjct: 61 VSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP 112
>gi|222418570 hypothetical protein LOC728591 isoform b [Homo
sapiens]
Length = 139
Score = 157 bits (396), Expect = 8e-39
Identities = 80/80 (100%), Positives = 80/80 (100%)
Query: 103 MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ 162
MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ
Sbjct: 1 MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ 60
Query: 163 VSKRQQVDQLPRMQENLVKT 182
VSKRQQVDQLPRMQENLVKT
Sbjct: 61 VSKRQQVDQLPRMQENLVKT 80
>gi|222418567 hypothetical protein LOC728591 isoform b [Homo
sapiens]
Length = 139
Score = 157 bits (396), Expect = 8e-39
Identities = 80/80 (100%), Positives = 80/80 (100%)
Query: 103 MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ 162
MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ
Sbjct: 1 MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQ 60
Query: 163 VSKRQQVDQLPRMQENLVKT 182
VSKRQQVDQLPRMQENLVKT
Sbjct: 61 VSKRQQVDQLPRMQENLVKT 80
>gi|222418572 hypothetical protein LOC728591 isoform c [Homo
sapiens]
Length = 141
Score = 150 bits (380), Expect = 6e-37
Identities = 77/77 (100%), Positives = 77/77 (100%)
Query: 106 ESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSK 165
ESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSK
Sbjct: 6 ESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSK 65
Query: 166 RQQVDQLPRMQENLVKT 182
RQQVDQLPRMQENLVKT
Sbjct: 66 RQQVDQLPRMQENLVKT 82
>gi|55749708 outer dense fiber of sperm tails 2-like isoform b [Homo
sapiens]
Length = 513
Score = 51.6 bits (122), Expect = 5e-07
Identities = 56/191 (29%), Positives = 97/191 (50%), Gaps = 25/191 (13%)
Query: 34 SIFELRHKITELEAKLN-TDNEGSEWKTRYE------TQLELNDE-LEKQIVYLKEKVEK 85
+I +L +I + EAKL+ T + + WK+ YE T+LE+ E ++KQI+ L E ++K
Sbjct: 128 AIEKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINLLEDLKK 187
Query: 86 I--HGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKI 143
+ HG +S +V+ +E N L + KT + +K + +E E Q++
Sbjct: 188 MEDHGKNSCEEILRKVHS---IEYENETLNLENTKLKTTLAALKDEVVSVENELSELQEV 244
Query: 144 NNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQ-ENLV-KTGRYNPAKQKTVSAKRGPVK 201
+++T L EM + QV K Q+ ++ + + ENL+ K + K K V RG ++
Sbjct: 245 EKKQKT-LIEMYK----TQVQKLQEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQME 299
Query: 202 KITRPNHLPEL 212
+HL EL
Sbjct: 300 -----SHLKEL 305
>gi|55749696 outer dense fiber of sperm tails 2-like isoform a [Homo
sapiens]
Length = 644
Score = 51.6 bits (122), Expect = 5e-07
Identities = 56/191 (29%), Positives = 97/191 (50%), Gaps = 25/191 (13%)
Query: 34 SIFELRHKITELEAKLN-TDNEGSEWKTRYE------TQLELNDE-LEKQIVYLKEKVEK 85
+I +L +I + EAKL+ T + + WK+ YE T+LE+ E ++KQI+ L E ++K
Sbjct: 259 AIEKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINLLEDLKK 318
Query: 86 I--HGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKI 143
+ HG +S +V+ +E N L + KT + +K + +E E Q++
Sbjct: 319 MEDHGKNSCEEILRKVHS---IEYENETLNLENTKLKTTLAALKDEVVSVENELSELQEV 375
Query: 144 NNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQ-ENLV-KTGRYNPAKQKTVSAKRGPVK 201
+++T L EM + QV K Q+ ++ + + ENL+ K + K K V RG ++
Sbjct: 376 EKKQKT-LIEMYK----TQVQKLQEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQME 430
Query: 202 KITRPNHLPEL 212
+HL EL
Sbjct: 431 -----SHLKEL 436
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 49.3 bits (116), Expect = 2e-06
Identities = 46/177 (25%), Positives = 86/177 (48%), Gaps = 16/177 (9%)
Query: 19 QQLLEEVRKKDAVQLSIFELRHKITELEAKLNTD--NEGSEWKTRYETQLELNDELEK-- 74
Q+L +EV + VQL +F+L H E+E KLN + ++ E + + ++ DEL++
Sbjct: 210 QRLKDEVVRAQ-VQLQLFKLYHNEVEIE-KLNKELASKNKEIEKDKKRMDKVEDELKEKK 267
Query: 75 ----QIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYA 130
+++ ++++EK L+ R E+ + +K+LE KK+L++ K+Y
Sbjct: 268 KELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYK 327
Query: 131 LK------LEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVK 181
+ LE+E + +K E + E SQ G + QV + R++E K
Sbjct: 328 KRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASK 384
Score = 28.5 bits (62), Expect = 4.5
Identities = 19/79 (24%), Positives = 38/79 (48%), Gaps = 9/79 (11%)
Query: 73 EKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALK 132
EK + LKEK E++ + + E+M + L+Q++ + L+ ++KY
Sbjct: 668 EKAVDKLKEKKERL---------TEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSD 718
Query: 133 LEQESKAYQKINNERRTYL 151
LEQ + +N + ++ L
Sbjct: 719 LEQTKTRHLALNLQEKSKL 737
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.5 bits (114), Expect = 4e-06
Identities = 53/193 (27%), Positives = 90/193 (46%), Gaps = 18/193 (9%)
Query: 2 KEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTR 61
+E R++ T R +Q+ ++ K+D + E R + +LE + E E + R
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEE----ERRERWLKLE-----EEERREQQER 502
Query: 62 YETQLELN-DELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
E QL +E +Q + +E+ E++ RL S + R E LLK+ EE+K
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQ----QRLRSEQQLRREQEERREQLLKR--EEEK 556
Query: 121 TLESQVKYYALKLEQESKAYQ--KINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQEN 178
LE + + LK EQE + Q K ERR + Q L Q KR++V++L + +
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 179 LVKTGRYNPAKQK 191
+ R P +++
Sbjct: 617 EQRLKREEPEEER 629
Score = 29.6 bits (65), Expect = 2.0
Identities = 42/196 (21%), Positives = 83/196 (42%), Gaps = 21/196 (10%)
Query: 2 KEERNYNFDGVSTNRLKQQLLEEVRKK-----DAVQLSIFELRHKITELEAKLNTDNEGS 56
+ ER Y D + +Q L EE K+ + EL+ + +L +
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 57 EWKTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLE 116
EW+ +Y + EL E E+ L+E+ EK +R R E + E + L
Sbjct: 1015 EWERQYRKKDELQQEEEQ---LLREEREK--RRLQERERQYREEEELQQEE----EQLLG 1065
Query: 117 EEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKR-QQVDQLPRM 175
EE++T Q +LE++ + +++ E L E + + ++ ++ ++L +
Sbjct: 1066 EERETRRRQ------ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 176 QENLVKTGRYNPAKQK 191
+E L++ R +Q+
Sbjct: 1120 EEQLLREEREKRRRQE 1135
Score = 28.9 bits (63), Expect = 3.4
Identities = 34/176 (19%), Positives = 73/176 (41%), Gaps = 8/176 (4%)
Query: 1 MKEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKT 60
++++R+ F +Q+ + R+++ Q+ E K E E +L +
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERDRKFREEEQ-QVRRQERERKFLEEEQQLRQERH-----R 1461
Query: 61 RYETQLELNDELEKQIVYLKEKVEKIHGNSSD--RLSSIRVYERMPVESLNTLLKQLEEE 118
++ + +L E E+Q ++ +E+ K R R + + S K LEEE
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE 1521
Query: 119 KKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPR 174
++ Q + L+ EQ+ + ++ R+ + + L Q + QQ+ + R
Sbjct: 1522 QQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 47.4 bits (111), Expect = 9e-06
Identities = 39/159 (24%), Positives = 80/159 (50%), Gaps = 34/159 (21%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRH----------KITELEAKL-----NTDNEGSEWKTR 61
LK+QL EEV+ K+A+ ++ RH + TE +A+L ++E ++W+T+
Sbjct: 1315 LKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1374
Query: 62 YETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
YET ++ +ELE+ L +++++ VE++N LE+ K
Sbjct: 1375 YETDAIQRTEELEEAKKKLAQRLQE---------------AEEAVEAVNAKCSSLEKTKH 1419
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTY---LAEMSQ 156
L+++++ + +E+ + A ++ ++R + LAE Q
Sbjct: 1420 RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458
Score = 31.6 bits (70), Expect = 0.53
Identities = 30/154 (19%), Positives = 60/154 (38%), Gaps = 24/154 (15%)
Query: 50 NTDNEGSEWKTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYER------- 102
N D +EWK +YE + +K+ L ++ K+ + L + ++R
Sbjct: 1448 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1507
Query: 103 -------------MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQES----KAYQKINN 145
+ L + KQLE EK L+S ++ LE E +A + N
Sbjct: 1508 EISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQ 1567
Query: 146 ERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENL 179
+ ++++ + +KR + + +Q +L
Sbjct: 1568 IKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Score = 30.8 bits (68), Expect = 0.90
Identities = 44/235 (18%), Positives = 95/235 (40%), Gaps = 51/235 (21%)
Query: 18 KQQLLEEVRKKD----AVQLSI-------FELRHKITELEAKLNTDNEGSEWKTRYETQL 66
KQQL E ++KKD A+ I +L+ K+ EL+A++ E E + ++
Sbjct: 1073 KQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKV 1132
Query: 67 E-LNDELEKQIVYLKEKVEKIHGNSSDRLSSIRV----YERM------------------ 103
E L +L +++ + E++E+ G +S ++ + +++M
Sbjct: 1133 EKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1192
Query: 104 -------------PVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTY 150
+++L + ++LE+EK + ++ +EQ KA + RT
Sbjct: 1193 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTL 1252
Query: 151 LAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITR 205
+M++ + ++R D + K N + + K + ++TR
Sbjct: 1253 EDQMNEHRSKAEETQRSVND----LTSQRAKLQTENGELSRQLDEKEALISQLTR 1303
Score = 29.3 bits (64), Expect = 2.6
Identities = 45/218 (20%), Positives = 87/218 (39%), Gaps = 39/218 (17%)
Query: 2 KEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTR 61
K E D V++N +E++ K A L LE ++N +E
Sbjct: 1221 KSEFKLELDDVTSN------MEQIIKAKA------NLEKMCRTLEDQMNEHRSKAE---- 1264
Query: 62 YETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKT 121
ETQ +ND + + K++ +G S +L T +QLE+ K+
Sbjct: 1265 -ETQRSVND-----LTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQ 1318
Query: 122 LESQVK-----YYAL------------KLEQESKAYQKINNERRTYLAEMSQGSGLHQVS 164
LE +VK +AL + E+E++A ++ +E++Q ++
Sbjct: 1319 LEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1378
Query: 165 KRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKK 202
Q+ ++L ++ L + + + V+AK ++K
Sbjct: 1379 AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 46.6 bits (109), Expect = 2e-05
Identities = 40/159 (25%), Positives = 78/159 (49%), Gaps = 34/159 (21%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRHKI--------------TELEAKLNTDN-EGSEWKTR 61
LK+QL EE++ K+A+ ++ RH EL+ L+ N E ++W+T+
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 62 YETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
YET ++ +ELE+ L ++++ + VE++N LE+ K+
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEH---------------VEAVNAKCASLEKTKQ 1425
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTY---LAEMSQ 156
L+++V+ L +E+ + A ++ ++R + LAE Q
Sbjct: 1426 RLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQ 1464
Score = 37.0 bits (84), Expect = 0.013
Identities = 33/172 (19%), Positives = 81/172 (47%), Gaps = 10/172 (5%)
Query: 12 VSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDE 71
+ N+ ++ +++R+ L L+H+ T + + +E + + + +
Sbjct: 1167 IEMNKKREAEFQKMRR----DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222
Query: 72 LEKQIVYLKEKVEKIHGNSSDRLSSIRVYERM--PVESLNTLLKQLEEEKKTLESQVKYY 129
LEK+ +K +++ + N + E+M +E + LK EEE++ L + +
Sbjct: 1223 LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ 1282
Query: 130 ALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVK 181
+L+ ES + + +E+ ++++S+G + + QQ+++L R E +K
Sbjct: 1283 RGRLQTESGEFSRQLDEKEALVSQLSRG----KQAFTQQIEELKRQLEEEIK 1330
Score = 33.9 bits (76), Expect = 0.11
Identities = 40/191 (20%), Positives = 79/191 (41%), Gaps = 28/191 (14%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKL-NTDNEGSEWKTRYE---TQLEL 68
S + KQ+L EV + + L + L+ K N D +EWK + E +LE
Sbjct: 1419 SLEKTKQRLQNEV---EDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
Query: 69 NDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYER-----------------MPVESLNTL 111
+ + + + K++ + S D+L +++ + + L +
Sbjct: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1535
Query: 112 LKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQ 171
KQ+E+EK L++ ++ LE E +I E +E+ + K +++DQ
Sbjct: 1536 KKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR----KIAEKDEEIDQ 1591
Query: 172 LPRMQENLVKT 182
L R +V++
Sbjct: 1592 LKRNHIRIVES 1602
Score = 30.8 bits (68), Expect = 0.90
Identities = 48/227 (21%), Positives = 89/227 (39%), Gaps = 50/227 (22%)
Query: 18 KQQLLEEVRKKD------------------AVQLSIFELRHKITELEAKLNTDN------ 53
KQQL E+++KK+ +Q I EL+ +I ELE ++ +
Sbjct: 1079 KQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKA 1138
Query: 54 ---------EGSEWKTRYE-------TQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSI 97
E E R E Q+E+N + E + ++ +E+ +++
Sbjct: 1139 EKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATL 1198
Query: 98 RVYERMPV-------ESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTY 150
R V ++L + ++LE+EK ++ ++ A +E SKA + RT
Sbjct: 1199 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTL 1258
Query: 151 LAEMSQGSGLHQVSKRQQVD---QLPRMQENLVKTGRYNPAKQKTVS 194
++S+ + +R D Q R+Q + R K+ VS
Sbjct: 1259 EDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVS 1305
Score = 29.6 bits (65), Expect = 2.0
Identities = 28/125 (22%), Positives = 49/125 (39%), Gaps = 1/125 (0%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKITELE-AKLNTDNEGSEWKTRYETQLELNDE 71
S LK+QL R+ + +Q I ELR + + E ++ + E + R + N
Sbjct: 1669 SQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTS 1728
Query: 72 LEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYAL 131
L L+ + ++ G D L R E +++ EE KK ++ +
Sbjct: 1729 LINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1788
Query: 132 KLEQE 136
K E
Sbjct: 1789 KKNME 1793
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 46.6 bits (109), Expect = 2e-05
Identities = 40/159 (25%), Positives = 78/159 (49%), Gaps = 34/159 (21%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRHKI--------------TELEAKLNTDN-EGSEWKTR 61
LK+QL EE++ K+A+ ++ RH EL+ L+ N E ++W+T+
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 62 YETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
YET ++ +ELE+ L ++++ + VE++N LE+ K+
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEH---------------VEAVNAKCASLEKTKQ 1425
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTY---LAEMSQ 156
L+++V+ L +E+ + A ++ ++R + LAE Q
Sbjct: 1426 RLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQ 1464
Score = 37.0 bits (84), Expect = 0.013
Identities = 33/172 (19%), Positives = 81/172 (47%), Gaps = 10/172 (5%)
Query: 12 VSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDE 71
+ N+ ++ +++R+ L L+H+ T + + +E + + + +
Sbjct: 1167 IEMNKKREAEFQKMRR----DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1222
Query: 72 LEKQIVYLKEKVEKIHGNSSDRLSSIRVYERM--PVESLNTLLKQLEEEKKTLESQVKYY 129
LEK+ +K +++ + N + E+M +E + LK EEE++ L + +
Sbjct: 1223 LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ 1282
Query: 130 ALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVK 181
+L+ ES + + +E+ ++++S+G + + QQ+++L R E +K
Sbjct: 1283 RGRLQTESGEFSRQLDEKEALVSQLSRG----KQAFTQQIEELKRQLEEEIK 1330
Score = 33.9 bits (76), Expect = 0.11
Identities = 40/191 (20%), Positives = 79/191 (41%), Gaps = 28/191 (14%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKL-NTDNEGSEWKTRYE---TQLEL 68
S + KQ+L EV + + L + L+ K N D +EWK + E +LE
Sbjct: 1419 SLEKTKQRLQNEV---EDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
Query: 69 NDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYER-----------------MPVESLNTL 111
+ + + + K++ + S D+L +++ + + L +
Sbjct: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1535
Query: 112 LKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQ 171
KQ+E+EK L++ ++ LE E +I E +E+ + K +++DQ
Sbjct: 1536 KKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR----KIAEKDEEIDQ 1591
Query: 172 LPRMQENLVKT 182
L R +V++
Sbjct: 1592 LKRNHIRIVES 1602
Score = 30.8 bits (68), Expect = 0.90
Identities = 48/227 (21%), Positives = 89/227 (39%), Gaps = 50/227 (22%)
Query: 18 KQQLLEEVRKKD------------------AVQLSIFELRHKITELEAKLNTDN------ 53
KQQL E+++KK+ +Q I EL+ +I ELE ++ +
Sbjct: 1079 KQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKA 1138
Query: 54 ---------EGSEWKTRYE-------TQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSI 97
E E R E Q+E+N + E + ++ +E+ +++
Sbjct: 1139 EKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATL 1198
Query: 98 RVYERMPV-------ESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTY 150
R V ++L + ++LE+EK ++ ++ A +E SKA + RT
Sbjct: 1199 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTL 1258
Query: 151 LAEMSQGSGLHQVSKRQQVD---QLPRMQENLVKTGRYNPAKQKTVS 194
++S+ + +R D Q R+Q + R K+ VS
Sbjct: 1259 EDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVS 1305
Score = 29.6 bits (65), Expect = 2.0
Identities = 28/125 (22%), Positives = 49/125 (39%), Gaps = 1/125 (0%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKITELE-AKLNTDNEGSEWKTRYETQLELNDE 71
S LK+QL R+ + +Q I ELR + + E ++ + E + R + N
Sbjct: 1669 SQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTS 1728
Query: 72 LEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYAL 131
L L+ + ++ G D L R E +++ EE KK ++ +
Sbjct: 1729 LINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1788
Query: 132 KLEQE 136
K E
Sbjct: 1789 KKNME 1793
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 46.6 bits (109), Expect = 2e-05
Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 31/156 (19%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEG---------------SEWKTR 61
LK QL EE + K+A+ ++ RH L + + EG ++W+T+
Sbjct: 1318 LKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1377
Query: 62 YETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
YET ++ +ELE+ L +++++ + VE++N LE+ K+
Sbjct: 1378 YETDAIQRTEELEEAKKKLAQRLQEAEEH---------------VEAVNAKCASLEKTKQ 1422
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQ 156
L+++V+ L +E+ + A ++ ++R + +S+
Sbjct: 1423 RLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSE 1458
Score = 43.9 bits (102), Expect = 1e-04
Identities = 44/191 (23%), Positives = 81/191 (42%), Gaps = 28/191 (14%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKL-NTDNEGSEWKTRYE---TQLEL 68
S + KQ+L EV + + L + L+ K N D SEWK +YE +LE
Sbjct: 1416 SLEKTKQRLQNEV---EDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
Query: 69 NDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYER-----------------MPVESLNTL 111
+ + + + KV+ ++ S D+L ++R + + L +
Sbjct: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
Query: 112 LKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQ 171
KQ+E+EK +++ ++ LE E +I E +E+ + K +++DQ
Sbjct: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR----KIAEKDEEIDQ 1588
Query: 172 LPRMQENLVKT 182
L R +V+T
Sbjct: 1589 LKRNHTRVVET 1599
Score = 27.7 bits (60), Expect = 7.6
Identities = 33/175 (18%), Positives = 73/175 (41%), Gaps = 22/175 (12%)
Query: 37 ELRHKITELEAKLNTDNEGSEWKTRYETQLELNDEL-----------EKQIVYLKEK--V 83
+L KI L T+ E + K ++ + DEL EK + LKEK +
Sbjct: 834 KLFFKIKPLLKSAETEKEMATMKEEFQ---KTKDELAKSEAKRKELEEKMVTLLKEKNDL 890
Query: 84 EKIHGNSSDRLSSIR------VYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQES 137
+ + +D L+ + ++ +E+ + + EE++ + +++ KLE E
Sbjct: 891 QLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDEC 950
Query: 138 KAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKT 192
+K ++ LA++ + + + +++ + E + K + A Q+T
Sbjct: 951 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQET 1005
Score = 27.3 bits (59), Expect = 10.0
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 15/88 (17%)
Query: 52 DNEGSEWKTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTL 111
+++ SE KT+ E Q L ++L Q L+ + + Y R ++ + L
Sbjct: 1256 EDQVSELKTKEEEQQRLINDLTAQRARLQTEAGE--------------YSRQ-LDEKDAL 1300
Query: 112 LKQLEEEKKTLESQVKYYALKLEQESKA 139
+ QL K+ Q++ +LE+E+KA
Sbjct: 1301 VSQLSRSKQASTQQIEELKHQLEEETKA 1328
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 45.4 bits (106), Expect = 4e-05
Identities = 39/159 (24%), Positives = 77/159 (48%), Gaps = 34/159 (21%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRHKI--------TELEAKL-------NTDNEGSEWKTR 61
LK+QL EE++ K A+ ++ RH E EAK ++E ++W+T+
Sbjct: 1319 LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTK 1378
Query: 62 YETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
YET ++ +ELE+ L ++++ + VE++N LE+ K+
Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEH---------------VEAVNAKCASLEKTKQ 1423
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTY---LAEMSQ 156
L+++V+ + +E+ + A ++ ++R + LAE Q
Sbjct: 1424 RLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462
Score = 40.0 bits (92), Expect = 0.001
Identities = 34/172 (19%), Positives = 82/172 (47%), Gaps = 10/172 (5%)
Query: 12 VSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDE 71
+ N+ ++ +++R+ L L+H+ T + + +E + + + +
Sbjct: 1165 IEMNKKREAEFQKMRR----DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220
Query: 72 LEKQIVYLKEKVEKIHGNSSDRLSSIRVYERM--PVESLNTLLKQLEEEKKTLESQVKYY 129
LEK+ +K +++ + N + E+M +E + +K EEE++ L + +
Sbjct: 1221 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280
Query: 130 ALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVK 181
+L+ ES Y + +E+ T ++++S+G + + QQ+++L R E +K
Sbjct: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRG----KQAFTQQIEELKRQLEEEIK 1328
Score = 34.3 bits (77), Expect = 0.081
Identities = 38/191 (19%), Positives = 79/191 (41%), Gaps = 28/191 (14%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKL-NTDNEGSEWKTRYE---TQLEL 68
S + KQ+L EV + + + + L+ K N D +EWK + E +LE
Sbjct: 1417 SLEKTKQRLQNEV---EDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1473
Query: 69 NDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYER-----------------MPVESLNTL 111
+ + + + K++ + S D+L +++ + + L +
Sbjct: 1474 SQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1533
Query: 112 LKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQ 171
KQ+E+EK L++ ++ LE E +I E +E+ + K +++DQ
Sbjct: 1534 KKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR----KIAEKDEEIDQ 1589
Query: 172 LPRMQENLVKT 182
+ R +V++
Sbjct: 1590 MKRNHIRIVES 1600
Score = 30.8 bits (68), Expect = 0.90
Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 3/132 (2%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKITELE-AKLNTDNEGSEWKTRYETQLELNDE 71
S LK+QL R+ + +Q I ELR + + E ++ + E + R + N
Sbjct: 1667 SQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTS 1726
Query: 72 LEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYAL 131
L L+ + +I G D + R E +++ EE KK ++ +
Sbjct: 1727 LINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1786
Query: 132 K--LEQESKAYQ 141
K LEQ K Q
Sbjct: 1787 KKNLEQTVKDLQ 1798
Score = 29.6 bits (65), Expect = 2.0
Identities = 40/216 (18%), Positives = 89/216 (41%), Gaps = 47/216 (21%)
Query: 18 KQQLLEEVRKKD----AVQLSI-------FELRHKITELEAKLNTDNEGSEWKTRYETQL 66
KQQL E+++KK+ +Q I +L+ KI EL+A++ E E + +
Sbjct: 1077 KQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKA 1136
Query: 67 ELN-DELEKQIVYLKEKVEKIHGNSSDRLSSIRV----YERM------------------ 103
E +L +++ + E++E+ G +S ++ + +++M
Sbjct: 1137 EKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATL 1196
Query: 104 -------------PVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTY 150
+++L + ++LE+EK ++ ++ A +E SKA + R
Sbjct: 1197 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRAL 1256
Query: 151 LAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYN 186
++S+ + +R D + ++G Y+
Sbjct: 1257 EDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYS 1292
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 44.7 bits (104), Expect = 6e-05
Identities = 46/180 (25%), Positives = 80/180 (44%), Gaps = 33/180 (18%)
Query: 10 DGVSTNRLKQQLLEEVRKKDA----VQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQ 65
+ VS R Q+ + ++ +K+ + + +LR + ++EAK +E E + + +
Sbjct: 820 EAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEK 879
Query: 66 LE-------------------LNDEL---EKQIVYLKEKVEKIHGNSSDRLSSIRVYERM 103
LE +NDEL E+ + L+ K+ K + N+S SI
Sbjct: 880 LENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 939
Query: 104 PVESLNTLLKQLEEEKKTLESQVKYYALKLE------QESKA-YQKINNERRTYLAEMSQ 156
+S K+ EEEKK LE ++ K+E QE KA Y++ +E +T E+ Q
Sbjct: 940 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 999
Score = 35.0 bits (79), Expect = 0.048
Identities = 41/176 (23%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 10 DGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELN 69
D TN Q L+ +++ + L E +K EL N E E++ ET +
Sbjct: 1065 DTKQTNAKLQNELDTLKENN---LKNVEELNKSKELLTVENQKME--EFRKEIETLKQAA 1119
Query: 70 DELEKQIVYLKEKVEKIH---GNSSDRLSSIRVYERMPVESLNTLL----------KQLE 116
+ +Q+ L+E+ K+ G S D ++S + E N LL K +
Sbjct: 1120 AQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDAD 1179
Query: 117 EEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQL 172
EEK +L+ + + L ++ +K+ NE E + LH V + + D++
Sbjct: 1180 EEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV 1235
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 44.7 bits (104), Expect = 6e-05
Identities = 46/180 (25%), Positives = 80/180 (44%), Gaps = 33/180 (18%)
Query: 10 DGVSTNRLKQQLLEEVRKKDA----VQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQ 65
+ VS R Q+ + ++ +K+ + + +LR + ++EAK +E E + + +
Sbjct: 855 EAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEK 914
Query: 66 LE-------------------LNDEL---EKQIVYLKEKVEKIHGNSSDRLSSIRVYERM 103
LE +NDEL E+ + L+ K+ K + N+S SI
Sbjct: 915 LENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 974
Query: 104 PVESLNTLLKQLEEEKKTLESQVKYYALKLE------QESKA-YQKINNERRTYLAEMSQ 156
+S K+ EEEKK LE ++ K+E QE KA Y++ +E +T E+ Q
Sbjct: 975 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 1034
Score = 35.0 bits (79), Expect = 0.048
Identities = 41/176 (23%), Positives = 73/176 (41%), Gaps = 18/176 (10%)
Query: 10 DGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELN 69
D TN Q L+ +++ + L E +K EL N E E++ ET +
Sbjct: 1100 DTKQTNAKLQNELDTLKENN---LKNVEELNKSKELLTVENQKME--EFRKEIETLKQAA 1154
Query: 70 DELEKQIVYLKEKVEKIH---GNSSDRLSSIRVYERMPVESLNTLL----------KQLE 116
+ +Q+ L+E+ K+ G S D ++S + E N LL K +
Sbjct: 1155 AQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDAD 1214
Query: 117 EEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQL 172
EEK +L+ + + L ++ +K+ NE E + LH V + + D++
Sbjct: 1215 EEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV 1270
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 43.9 bits (102), Expect = 1e-04
Identities = 39/159 (24%), Positives = 75/159 (47%), Gaps = 34/159 (21%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRHKI--------TELEAKL-------NTDNEGSEWKTR 61
LK+Q+ EE + K+A+ ++ RH E EAK ++E ++W+T+
Sbjct: 1319 LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTK 1378
Query: 62 YETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
YET ++ +ELE+ L +++++ N+ E+ N+ LE+ K+
Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQEAEENT---------------ETANSKCASLEKTKQ 1423
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTY---LAEMSQ 156
L+ +V+ LE+ A ++ ++R + LAE Q
Sbjct: 1424 RLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQ 1462
Score = 37.4 bits (85), Expect = 0.010
Identities = 54/226 (23%), Positives = 97/226 (42%), Gaps = 43/226 (19%)
Query: 16 RLKQQLLEEVRKKDAVQLSIFELRHKITEL-EAKLN-------TDNEGSEWKTRYETQLE 67
R+KQ+L +E K +++ I ++ I L ++K N +++ SE K + E Q +
Sbjct: 1216 RVKQKLEKE---KSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQ 1272
Query: 68 LNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVK 127
L +L Q K +++ +G S R+ +S L +QLEE K+ +E + K
Sbjct: 1273 LIHDLNMQ----KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETK 1328
Query: 128 Y-----YALKL--------------EQESKA-----YQKINNE----RRTYLAEMSQGSG 159
+AL+ EQE+KA K N+E R Y + Q +
Sbjct: 1329 AKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTE 1388
Query: 160 LHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITR 205
+ +K++ +L +EN + +KT +G V+ + R
Sbjct: 1389 ELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMR 1434
Score = 30.4 bits (67), Expect = 1.2
Identities = 29/171 (16%), Positives = 73/171 (42%), Gaps = 22/171 (12%)
Query: 12 VSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDE 71
+ N+ ++ +++R+ L L+H+ T + + +E + + + +
Sbjct: 1165 IEMNKKREAEFQKMRR----DLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQK 1220
Query: 72 LEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYAL 131
LEK+ LK +++ + N +E+L+ +E +T+E Q
Sbjct: 1221 LEKEKSELKMEIDDMASN---------------IEALSKSKSNIERTCRTVEDQFSEIKA 1265
Query: 132 KLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQ-VDQLPRMQENLVK 181
K EQ+++ +N ++ + G H+V +++ + QL + ++ L +
Sbjct: 1266 KDEQQTQLIHDLNMQKAR--LQTQNGELSHRVEEKESLISQLTKSKQALTQ 1314
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 43.9 bits (102), Expect = 1e-04
Identities = 38/159 (23%), Positives = 78/159 (49%), Gaps = 34/159 (21%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRH----------KITELEAKL-----NTDNEGSEWKTR 61
LK+QL EE + K+A+ ++ RH + TE +A+L ++E ++W+T+
Sbjct: 1317 LKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1376
Query: 62 YETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
YET ++ +ELE+ L ++++ VE++N LE+ K
Sbjct: 1377 YETDAIQRTEELEEAKKKLAQRLQD---------------AEEAVEAVNAKCSSLEKTKH 1421
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTY---LAEMSQ 156
L+++++ + +E+ + A ++ ++R + LAE Q
Sbjct: 1422 RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1460
Score = 32.3 bits (72), Expect = 0.31
Identities = 32/151 (21%), Positives = 57/151 (37%), Gaps = 24/151 (15%)
Query: 50 NTDNEGSEWKTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYER------- 102
N D +EWK +YE + +K+ L ++ K+ + L + ++R
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 103 -------------MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRT 149
V L + KQLE EK L+S ++ LE E + E
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 150 YLAEMSQGSGLHQVSKRQQVDQLPRMQENLV 180
AE+ + K ++++Q R + +V
Sbjct: 1570 IKAEIER----KLAEKDEEMEQAKRNHQRVV 1596
Score = 30.0 bits (66), Expect = 1.5
Identities = 26/117 (22%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 59 KTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEE 118
K ++ EL ++++ + +K+K+EK L + +E + LE+
Sbjct: 1196 KKHADSVAELGEQIDN-LQRVKQKLEKEKSEFKLELDDVT----SNMEQIIKAKANLEKV 1250
Query: 119 KKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQ-VDQLPR 174
+TLE Q Y +KLE+ ++ +R E G Q+ +++ + QL R
Sbjct: 1251 SRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTE--NGELARQLEEKEALISQLTR 1305
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/153 (22%), Positives = 73/153 (47%), Gaps = 31/153 (20%)
Query: 14 TNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEG---------------SEW 58
T LK+QL EE + K+A+ ++ RH L + + EG ++W
Sbjct: 1313 TEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1372
Query: 59 KTRYETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEE 117
+T+YET ++ +ELE+ K+K+ + +S ++ VE++N LE+
Sbjct: 1373 RTKYETDAIQRTEELEE----AKKKLAQRLQDSEEQ-----------VEAVNAKCASLEK 1417
Query: 118 EKKTLESQVKYYALKLEQESKAYQKINNERRTY 150
K+ L+ +V+ + +E+ + ++ ++R +
Sbjct: 1418 TKQRLQGEVEDLMVDVERANSLAAALDKKQRNF 1450
Score = 42.4 bits (98), Expect = 3e-04
Identities = 48/227 (21%), Positives = 92/227 (40%), Gaps = 50/227 (22%)
Query: 18 KQQLLEEVRKKD------------------AVQLSIFELRHKITELEAKLN--------T 51
KQQL E ++KKD Q I EL+ +I ELE ++ T
Sbjct: 1074 KQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKT 1133
Query: 52 DNEGSEWKTRYE--------------TQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSI 97
+ + S++ E TQ+ELN + E + + L+ +E+ ++++
Sbjct: 1134 EKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAAL 1193
Query: 98 RVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNER-------RTY 150
R V L + L+ K+ LE + + L+++ S + + ++ + RT
Sbjct: 1194 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTL 1253
Query: 151 LAEMSQGSGLHQVSKR---QQVDQLPRMQENLVKTGRYNPAKQKTVS 194
++S+ G ++ +R + Q R+Q + R K+ VS
Sbjct: 1254 EDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVS 1300
Score = 39.3 bits (90), Expect = 0.003
Identities = 43/156 (27%), Positives = 74/156 (47%), Gaps = 19/156 (12%)
Query: 23 EEVRKKDAVQLSIFELRHKITELE---AKLNTDNEGSEWKTRYETQLELN--DELEKQIV 77
E KK ++ EL+ I +LE AK+ + +E K + T+ EL+ DE ++
Sbjct: 936 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE-ELSGLDETIAKLT 994
Query: 78 YLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQES 137
K+ +++ H + D L + E V SLN +LE++ + LES LEQE
Sbjct: 995 REKKALQEAHQQALDDLQA----EEDKVNSLNKTKSKLEQQVEDLES-------SLEQEK 1043
Query: 138 KAYQKINNERRTYLAE--MSQGSGLHQVSKRQQVDQ 171
K + +R + ++Q S L + +QQ+D+
Sbjct: 1044 KLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDE 1079
Score = 27.7 bits (60), Expect = 7.6
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 31/146 (21%)
Query: 19 QQLLEEVRKKDAVQLSIFELRHKITELE-AKLNTDNEGSEWKTRYETQLELNDELEKQIV 77
+ ++ +RKK A S+ EL +I L+ K + E SE+K + +L+ +E +
Sbjct: 1187 EAMVAALRKKHAD--SVAELGEQIDNLQRVKQKLEKEKSEFKLEID---DLSSSMES-VS 1240
Query: 78 YLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLL--------------KQLEEE----- 118
K +EKI D+LS R SL+ L +QLEE+
Sbjct: 1241 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVS 1300
Query: 119 -----KKTLESQVKYYALKLEQESKA 139
K+ Q + +LE+E+KA
Sbjct: 1301 QLSRSKQAFTQQTEELKRQLEEENKA 1326
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 43.1 bits (100), Expect = 2e-04
Identities = 38/159 (23%), Positives = 76/159 (47%), Gaps = 34/159 (21%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRHKI--------TELEAKL-------NTDNEGSEWKTR 61
LK+QL EE + K + ++ RH E EAK ++E ++W+T+
Sbjct: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTK 1378
Query: 62 YETQ-LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKK 120
YET ++ +ELE+ L ++++ + VE++N+ LE+ K+
Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQDAEEH---------------VEAVNSKCASLEKTKQ 1423
Query: 121 TLESQVKYYALKLEQESKAYQKINNERRTY---LAEMSQ 156
L+++V+ + +E+ + A ++ ++R + LAE Q
Sbjct: 1424 RLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQ 1462
Score = 38.1 bits (87), Expect = 0.006
Identities = 33/172 (19%), Positives = 81/172 (47%), Gaps = 10/172 (5%)
Query: 12 VSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDE 71
+ N+ ++ +++R+ L L+H+ T + + +E + ++ + +
Sbjct: 1165 IEMNKKREAEFQKMRR----DLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQK 1220
Query: 72 LEKQIVYLKEKVEKIHGNSSDRLSSIRVYERM--PVESLNTLLKQLEEEKKTLESQVKYY 129
LEK+ LK ++ + N + +E+M +E + +K EEE++ L +++
Sbjct: 1221 LEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQ 1280
Query: 130 ALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVK 181
+L ES + + +E+ ++++S+G + + QQ+++L R E K
Sbjct: 1281 KARLHTESGEFSRQLDEKDAMVSQLSRG----KQAFTQQIEELKRQLEEETK 1328
Score = 36.2 bits (82), Expect = 0.021
Identities = 41/191 (21%), Positives = 78/191 (40%), Gaps = 28/191 (14%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKL-NTDNEGSEWKTRYE---TQLEL 68
S + KQ+L EV + + + + L+ K N D +EWK +YE +LE
Sbjct: 1417 SLEKTKQRLQNEV---EDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473
Query: 69 NDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYER-----------------MPVESLNTL 111
+ + + + KV+ + S D L +++ + + L +
Sbjct: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
Query: 112 LKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQ 171
KQL+ EK L++ ++ LE E +I E +E+ + K +++DQ
Sbjct: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDR----KIAEKDEELDQ 1589
Query: 172 LPRMQENLVKT 182
L R +V++
Sbjct: 1590 LKRNHLRVVES 1600
Score = 33.9 bits (76), Expect = 0.11
Identities = 38/192 (19%), Positives = 80/192 (41%), Gaps = 47/192 (24%)
Query: 12 VSTNRLKQQLLEEVRKKDAVQLSI-----------FELRHKITELEAKLNTDNEGSEWKT 60
+ T KQQL E+++KK+ ++ +L+ KI EL+A++ E E +
Sbjct: 1071 MDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAER 1130
Query: 61 RYETQLELN-DELEKQIVYLKEKVEKIHGNSSDRLSSIRV----YERM------------ 103
+ E +L +++ + E++E+ G +S ++ + +++M
Sbjct: 1131 ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHE 1190
Query: 104 -------------------PVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKIN 144
++SL + ++LE+EK L+ ++ A +E SKA
Sbjct: 1191 ATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFE 1250
Query: 145 NERRTYLAEMSQ 156
RT ++S+
Sbjct: 1251 KMCRTLEDQLSE 1262
Score = 32.7 bits (73), Expect = 0.24
Identities = 36/135 (26%), Positives = 63/135 (46%), Gaps = 26/135 (19%)
Query: 13 STNRLKQQLLEEVRKKDAVQLSIFELRHKI-TELEAKLN-------TDNEGSEWKTRYET 64
S R+KQ+L +E K +++ I +L + T +AK N +++ SE KT+ E
Sbjct: 1213 SLQRVKQKLEKE---KSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEE 1269
Query: 65 QLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLES 124
Q L +EL Q K ++ G S +L + + ++ QL K+
Sbjct: 1270 QQRLINELSAQ----KARLHTESGEFSRQL-----------DEKDAMVSQLSRGKQAFTQ 1314
Query: 125 QVKYYALKLEQESKA 139
Q++ +LE+E+KA
Sbjct: 1315 QIEELKRQLEEETKA 1329
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 42.7 bits (99), Expect = 2e-04
Identities = 41/169 (24%), Positives = 75/169 (44%), Gaps = 9/169 (5%)
Query: 7 YNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTD-NEGSEWKTRYETQ 65
+N + V R + Q + +K+ L I +L +K+ L+ +L + NE K R +
Sbjct: 643 HNLEKVEGERKEAQDMLNHSEKEKNNLEI-DLNYKLKSLQQRLEQEVNEHKVTKARLTDK 701
Query: 66 LELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEE------- 118
+ +E + + EK K + ++ + V L+ LKQ +++
Sbjct: 702 HQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGN 761
Query: 119 KKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQ 167
K+ +E +VK L+LEQES + NE +T E GL + K++
Sbjct: 762 KERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQE 810
Score = 42.0 bits (97), Expect = 4e-04
Identities = 33/126 (26%), Positives = 68/126 (53%), Gaps = 13/126 (10%)
Query: 59 KTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVY---ERMPVESLNTLLKQL 115
KT Y+ + +L++E++ LK+++E+ S+ +L I E +L + + Q+
Sbjct: 430 KTIYKLEEQLHNEMQ-----LKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQI 484
Query: 116 EEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQV--DQLP 173
E+EK L+ ++ Y K EQE++ + + NE T ++ L +VS+ Q+ ++L
Sbjct: 485 EKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLED---LKKVSQNSQLANEKLS 541
Query: 174 RMQENL 179
++Q+ L
Sbjct: 542 QLQKQL 547
Score = 31.6 bits (70), Expect = 0.53
Identities = 43/218 (19%), Positives = 81/218 (37%), Gaps = 34/218 (15%)
Query: 2 KEERNYNFD-GVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITE--------LEAKLNTD 52
KE+ N D L+Q+L +EV + + + + I E +E KL +
Sbjct: 664 KEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEE 723
Query: 53 NEGSEWKTRYETQLELN-DELEKQIVYLKEKVEKIHGNSS---DRLSSIRVY-------- 100
E E Q+E L+ + ++K+E + GN D + ++ +
Sbjct: 724 REAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKR 783
Query: 101 ---------ERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYL 151
+ ++L L KQ+++E TL + +L Q +K Y+ + R
Sbjct: 784 LLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR--- 840
Query: 152 AEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAK 189
E+ Q Q+ ++E + + R N K
Sbjct: 841 -ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKK 877
Score = 28.1 bits (61), Expect = 5.8
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 72 LEKQIVYLKEKVEKIHG---NSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKY 128
L++++ +LK +EK+ G + D L+ + LN LK L++ LE +V
Sbjct: 634 LQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQR---LEQEVNE 690
Query: 129 YALKLEQESKAYQKINNERRTYLAEMSQ 156
+ + + + +Q I + + EM +
Sbjct: 691 HKVTKARLTDKHQSIEEAKSVAMCEMEK 718
Score = 27.3 bits (59), Expect = 10.0
Identities = 27/129 (20%), Positives = 58/129 (44%), Gaps = 16/129 (12%)
Query: 15 NRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELEK 74
N +++ +E K+ V+ + L+ ++ +L+ +E ++ + QLE ++L +
Sbjct: 496 NEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLR 555
Query: 75 QIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVK-----YY 129
++ K H S +S + ESLN ++L+E + LE+ YY
Sbjct: 556 TESDTAVRLRKSHTEMSKSISQL--------ESLN---RELQERNRILENSKSQTDKDYY 604
Query: 130 ALKLEQESK 138
L+ E++
Sbjct: 605 QLQAILEAE 613
>gi|134152674 rabaptin, RAB GTPase binding effector protein 1
isoform 2 [Homo sapiens]
Length = 829
Score = 42.7 bits (99), Expect = 2e-04
Identities = 43/199 (21%), Positives = 91/199 (45%), Gaps = 25/199 (12%)
Query: 16 RLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELEKQ 75
RL+Q+ + + +++ + I +LR +++E + + N +NE + + E + +EK+
Sbjct: 135 RLEQERTQWAQYRESAEREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKE 194
Query: 76 IVYLKEKV----EKIHGNSSDRLSSIRVY----------ERMPVESLNTLLKQLEEEKKT 121
I LK+K+ +KI + ++ + Y M V LNT L+E+ +
Sbjct: 195 IAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEK 254
Query: 122 LESQVKYYALKLEQESK-------AYQKINNE----RRTYLAEMSQGSGLHQVSKRQQVD 170
L ++ LEQE + +QK N++ +R + +M + + + +QV+
Sbjct: 255 LRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVE 314
Query: 171 QLPRMQENLVKTGRYNPAK 189
+L + + + R N K
Sbjct: 315 ELKKKDQEDDEQQRLNKRK 333
Score = 28.1 bits (61), Expect = 5.8
Identities = 24/112 (21%), Positives = 49/112 (43%), Gaps = 13/112 (11%)
Query: 68 LNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVK 127
L + L+ +I KE++ I ++ ER+ VE ++QL E+K +++
Sbjct: 723 LEETLQLEIENCKEEIASISSLKAE-------LERIKVEKGQATVEQLMFEEKNKAQRLQ 775
Query: 128 YYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQV------SKRQQVDQLP 173
EQ + + K++ + L + Q L ++ +K ++QLP
Sbjct: 776 TELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDINQLP 827
>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
1 [Homo sapiens]
Length = 862
Score = 42.7 bits (99), Expect = 2e-04
Identities = 43/199 (21%), Positives = 91/199 (45%), Gaps = 25/199 (12%)
Query: 16 RLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELEKQ 75
RL+Q+ + + +++ + I +LR +++E + + N +NE + + E + +EK+
Sbjct: 135 RLEQERTQWAQYRESAEREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKE 194
Query: 76 IVYLKEKV----EKIHGNSSDRLSSIRVY----------ERMPVESLNTLLKQLEEEKKT 121
I LK+K+ +KI + ++ + Y M V LNT L+E+ +
Sbjct: 195 IAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEK 254
Query: 122 LESQVKYYALKLEQESK-------AYQKINNE----RRTYLAEMSQGSGLHQVSKRQQVD 170
L ++ LEQE + +QK N++ +R + +M + + + +QV+
Sbjct: 255 LRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVE 314
Query: 171 QLPRMQENLVKTGRYNPAK 189
+L + + + R N K
Sbjct: 315 ELKKKDQEDDEQQRLNKRK 333
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 42.4 bits (98), Expect = 3e-04
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 25/184 (13%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEG-SEWKTRYETQLELNDELEKQ 75
L+Q+ ++E+ K +V + L + E E KL E E + ETQ + LE Q
Sbjct: 1474 LQQEQIQELEKCRSV---LEHLPMAVQEREQKLTVQREQIRELEKDRETQRNV---LEHQ 1527
Query: 76 IVYLKEK---VEKIHGNSSDRLSSIRVYERMPVE---------SLNTLLKQLEEEKKTLE 123
++ L++K +E G D + E + +E L+K+LE +++T
Sbjct: 1528 LLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQR 1587
Query: 124 SQVKYYALKLEQESKAYQKINNE------RRTYLAEMSQGSGLHQVSKRQQVDQLPRMQE 177
+ + L LE+ S+ Q +++ T LA Q S+R+Q+++L R +E
Sbjct: 1588 VALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKE 1647
Query: 178 NLVK 181
+L +
Sbjct: 1648 HLTQ 1651
Score = 29.3 bits (64), Expect = 2.6
Identities = 39/147 (26%), Positives = 64/147 (43%), Gaps = 19/147 (12%)
Query: 67 ELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESL-------NTLLKQLEEEK 119
EL D+LE+Q+ L KV + S R I V ++ E+ +L QL+E +
Sbjct: 1750 ELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQ 1809
Query: 120 KTL-ESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGS--GLHQVSK------RQQVD 170
+ L + + AL+ EQ+ Q+ ER A+ QG+ H K + +
Sbjct: 1810 RALAQRDQELEALQQEQQQAQGQE---ERVKEKADALQGALEQAHMTLKERHGELQDHKE 1866
Query: 171 QLPRMQENLVKTGRYNPAKQKTVSAKR 197
Q R++E L GR A ++ + R
Sbjct: 1867 QARRLEEELAVEGRRVQALEEVLGDLR 1893
Score = 28.9 bits (63), Expect = 3.4
Identities = 41/206 (19%), Positives = 87/206 (42%), Gaps = 25/206 (12%)
Query: 12 VSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGS---------EWKTRY 62
V+ +L+ Q+ + K+ +Q + L+ ++ ++ + + + E KT
Sbjct: 785 VTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTAL 844
Query: 63 ETQLELNDELEKQIVYLKEKVEKIHGNSSDRLS-SIRVYERMPVE----------SLNTL 111
E Q + EK++ L+EK EK L+ ++ ER +E + +
Sbjct: 845 EQQKAAH---EKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 901
Query: 112 LKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQ 171
Q EEE+ ES + L+ E+E + + + + LA+ SQ L ++ + +V +
Sbjct: 902 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQ--QLERLRQDMKVQK 959
Query: 172 LPRMQENLVKTGRYNPAKQKTVSAKR 197
L + + + A+++ A R
Sbjct: 960 LKEQETTGILQTQLQEAQRELKEAAR 985
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 42.4 bits (98), Expect = 3e-04
Identities = 47/183 (25%), Positives = 84/183 (45%), Gaps = 23/183 (12%)
Query: 2 KEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTR 61
KE+ N D ++ QQ LE+ E HK T+ A+L N+ +++
Sbjct: 681 KEKSNMEIDMTYQLKVIQQSLEQE-----------EAEHKATK--ARLADKNK--IYESI 725
Query: 62 YETQLELNDELEKQIVY---LKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEE 118
E + E E+EK+++ LK+KVE + + R S + + + +N LLKQ
Sbjct: 726 EEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQ---- 781
Query: 119 KKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQEN 178
K L V+ LK+EQE++ N+ + +++ + + +Q+ + L M+ N
Sbjct: 782 KDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNT-LKMSEKQLKQENNHLMEMKMN 840
Query: 179 LVK 181
L K
Sbjct: 841 LEK 843
Score = 39.7 bits (91), Expect = 0.002
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 12/144 (8%)
Query: 23 EEVRKKDAVQLSIFELRHKITELEAKLNTDNE--GSEWKTRYETQLELNDELEKQIVYLK 80
+E+ +KDA S+ E +T A L + E ++ K E L DE E +K
Sbjct: 959 QELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDE-EISAAAIK 1017
Query: 81 EKVEK-------IHGNSSDRLSSIRVYERMPVESLN-TLLKQLEEEKKTLESQVKYYALK 132
+ EK + + ++L+ I + + PV+ N T +++ E+E + L ++K K
Sbjct: 1018 AQFEKQLLTERTLKTQAVNKLAEI-MNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK 1076
Query: 133 LEQESKAYQKINNERRTYLAEMSQ 156
L Q+ YQK NE + +AE SQ
Sbjct: 1077 LTQQMIKYQKELNEMQAQIAEESQ 1100
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 42.4 bits (98), Expect = 3e-04
Identities = 41/182 (22%), Positives = 80/182 (43%), Gaps = 14/182 (7%)
Query: 23 EEVRKKDAVQLSIFELRHK-ITELEAKLNTDNEGSEWKTRYETQLELND-ELEKQIVYLK 80
+E+ +K + + + ++K + + E KLN + E TQL+L D ++ +++ +
Sbjct: 349 KEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHAT 408
Query: 81 EKVEKIHGNSSDRLSSIRVYERMPVESLN------TLLKQLEEEKKTLESQVKYYALKLE 134
K +K+ + ++ +P +S N T LE+EK+ E ++K L+
Sbjct: 409 SKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLK 468
Query: 135 QESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVS 194
QE++ QK R L M +++ + V Q E + R+N A +
Sbjct: 469 QETQGLQKEKESREKEL--MGFSKSVNEARSKMDVAQ----SELDIYLSRHNTAVSQLTK 522
Query: 195 AK 196
AK
Sbjct: 523 AK 524
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 42.4 bits (98), Expect = 3e-04
Identities = 41/182 (22%), Positives = 80/182 (43%), Gaps = 14/182 (7%)
Query: 23 EEVRKKDAVQLSIFELRHK-ITELEAKLNTDNEGSEWKTRYETQLELND-ELEKQIVYLK 80
+E+ +K + + + ++K + + E KLN + E TQL+L D ++ +++ +
Sbjct: 349 KEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHAT 408
Query: 81 EKVEKIHGNSSDRLSSIRVYERMPVESLN------TLLKQLEEEKKTLESQVKYYALKLE 134
K +K+ + ++ +P +S N T LE+EK+ E ++K L+
Sbjct: 409 SKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLK 468
Query: 135 QESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVS 194
QE++ QK R L M +++ + V Q E + R+N A +
Sbjct: 469 QETQGLQKEKESREKEL--MGFSKSVNEARSKMDVAQ----SELDIYLSRHNTAVSQLTK 522
Query: 195 AK 196
AK
Sbjct: 523 AK 524
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 42.0 bits (97), Expect = 4e-04
Identities = 49/178 (27%), Positives = 75/178 (42%), Gaps = 37/178 (20%)
Query: 23 EEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELEKQIVYLKEK 82
EE +K+ I EL +I+EL+ L E++ ++ EKQ L E+
Sbjct: 1094 EEAAQKNMALKKIRELESQISELQEDL-------------ESERASRNKAEKQKRDLGEE 1140
Query: 83 VEKIHGNSSDRLSSIRVYERMPV---ESLNTLLKQLEEEKKTLESQ-----------VKY 128
+E + D L S + + + +N L K LEEE KT E+Q V+
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200
Query: 129 YALKLEQE-------SKAYQKINNERRTYLAEMS---QGSGLHQVSKRQQVDQLPRMQ 176
A +LEQ KA Q + NER E+ QG G + +++ QL +Q
Sbjct: 1201 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQ 1258
Score = 34.7 bits (78), Expect = 0.062
Identities = 33/140 (23%), Positives = 69/140 (49%), Gaps = 15/140 (10%)
Query: 18 KQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELN-DELEKQI 76
K++ L +VR+K QL+ ++ L+++L + + + + ET+L +EL ++
Sbjct: 850 KEEELVKVREK---QLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARL 906
Query: 77 VYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQE 136
K+++E+I + R VE + L+ EKK ++ ++ +LE+E
Sbjct: 907 TAKKQELEEICHDLEAR-----------VEEEEERCQHLQAEKKKMQQNIQELEEQLEEE 955
Query: 137 SKAYQKINNERRTYLAEMSQ 156
A QK+ E+ T A++ +
Sbjct: 956 ESARQKLQLEKVTTEAKLKK 975
Score = 32.7 bits (73), Expect = 0.24
Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 30/159 (18%)
Query: 18 KQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSE----WKTRYETQL-ELNDEL 72
+Q +LE+ K A + + E R I E L + E S+ K ++E + +L + L
Sbjct: 979 EQIILEDQNCKLAKEKKLLEDR--IAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 73 ---EKQIVYLKEKVEKIHGNSSD----------RLSSIRVYERMPVESLNTLLKQLEEEK 119
EKQ L++ K+ G+S+D +++ +++ E L L ++EEE
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
Query: 120 ----------KTLESQVKYYALKLEQESKAYQKINNERR 148
+ LESQ+ LE E + K ++R
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 1135
Score = 31.6 bits (70), Expect = 0.53
Identities = 47/214 (21%), Positives = 89/214 (41%), Gaps = 43/214 (20%)
Query: 24 EVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELND-------ELEKQI 76
E R+K+ LS+ + E +A+L N+ +++T E + D ELEK
Sbjct: 1470 EAREKETKALSLARALEEAMEQKAELERLNK--QFRTEMEDLMSSKDDVGKSVHELEKSK 1527
Query: 77 VYLKEKVEKIHGNSSDRLSSIRVYE----RMPVE----------SLNTLLKQLEEEKKTL 122
L+++VE++ + ++ E R+ V L +Q EE+KK L
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQL 1587
Query: 123 ESQVKYYALKLEQESK-------AYQKINNERRTYLAEM-----SQGSGLHQVSKRQ--- 167
QV+ +LE E K A +K+ + + A + ++ + Q+ K Q
Sbjct: 1588 VRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQM 1647
Query: 168 -----QVDQLPRMQENLVKTGRYNPAKQKTVSAK 196
++D +E ++ + N K K++ A+
Sbjct: 1648 KDCMRELDDTRASREEILAQAKENEKKLKSMEAE 1681
Score = 30.4 bits (67), Expect = 1.2
Identities = 36/162 (22%), Positives = 70/162 (43%), Gaps = 38/162 (23%)
Query: 19 QQLLEEVRKKDAVQLSIF-----ELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELE 73
+Q LE R + A ++ + + HK ++EA+L E + ++ + EL
Sbjct: 1219 KQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQ------ELQVKFNEGERVRTELA 1272
Query: 74 KQIVYLKEKVEKIHG--NSSDRLSSIRVYERMPVES------------------LNTLLK 113
++ L+ +++ + G + SD SS + +ES L+T LK
Sbjct: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLK 1332
Query: 114 QLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMS 155
Q+E+EK + Q LE+E +A + + T A+++
Sbjct: 1333 QVEDEKNSFREQ-------LEEEEEAKHNLEKQIATLHAQVA 1367
Score = 27.3 bits (59), Expect = 10.0
Identities = 30/162 (18%), Positives = 73/162 (45%), Gaps = 7/162 (4%)
Query: 16 RLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELEKQ 75
+L+ Q+ + +R+ D + S E+ + E E KL + + + +L + ++Q
Sbjct: 1642 KLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM---IQLQEELAAAERAKRQ 1698
Query: 76 IVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQ 135
++++ NSS + ++ + E+ +E+ + QLEEE + + + +L++
Sbjct: 1699 AQQERDELADEIANSSGK-GALALEEKRRLEAR---IAQLEEELEEEQGNTELINDRLKK 1754
Query: 136 ESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQE 177
+ +IN + + + Q +RQ + ++QE
Sbjct: 1755 ANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQE 1796
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 42.0 bits (97), Expect = 4e-04
Identities = 43/191 (22%), Positives = 87/191 (45%), Gaps = 11/191 (5%)
Query: 17 LKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELEKQI 76
LK+ L + +K+ +Q +L KI +++ K+ T + + RY+TQ E EL+ Q
Sbjct: 1399 LKEDLNKVRTEKETIQK---DLDAKIIDIQEKVKTITQVKKIGRRYKTQYE---ELKAQQ 1452
Query: 77 VYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQE 136
+ E + G+ ++ S++ ++ L L Q E + K+LESQV+ L ++
Sbjct: 1453 DKVMETSAQSSGDHQEQHVSVQ-----EMQELKETLNQAETKSKSLESQVENLQKTLSEK 1507
Query: 137 SKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAK 196
+ + + +E+S+ Q Q+ ++ E KT + A + ++
Sbjct: 1508 ETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHL 1567
Query: 197 RGPVKKITRPN 207
G ++T+ N
Sbjct: 1568 AGVKDQLTKEN 1578
Score = 36.6 bits (83), Expect = 0.016
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 25/142 (17%)
Query: 19 QQLLE--EVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRY-------------- 62
Q +LE E K + I +L H+I+ L+ KL + E TR
Sbjct: 823 QGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDT 882
Query: 63 ETQLELNDE-----LEKQIVYLKEKVE----KIHGNSSDRLSSIRVYERMPVESLNTLLK 113
ET L LN + +K+I LK+ + ++ SS R + + V+ L + L+
Sbjct: 883 ETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLR 942
Query: 114 QLEEEKKTLESQVKYYALKLEQ 135
Q EE+ L+ ++K +EQ
Sbjct: 943 QTEEQVNDLKERLKTSTSNVEQ 964
Score = 34.3 bits (77), Expect = 0.081
Identities = 37/184 (20%), Positives = 89/184 (48%), Gaps = 27/184 (14%)
Query: 18 KQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWK--------TRYETQLEL- 68
+++L+ E R+ +++L + +L +++ L K N + E ++ + TR + +LE
Sbjct: 65 QERLVNETRECQSLRLELEKLNNQLKALTEK-NKELEIAQDRNIAIQSQFTRTKEELEAE 123
Query: 69 -------NDELEKQIVYLKEKVEKIH-----GNSSDRLSSIRVYERMPVE-SLNTLLKQL 115
N+ L +++ YL E V++++ N++ +++ E + S+ K+L
Sbjct: 124 KRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRL 183
Query: 116 EEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRM 175
E+EK+ L SQ + +L+ ++ + E+ + E+ + +K+++V +L
Sbjct: 184 EQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELK----CNLENKKEEVSRLEEQ 239
Query: 176 QENL 179
L
Sbjct: 240 MNGL 243
Score = 32.3 bits (72), Expect = 0.31
Identities = 36/195 (18%), Positives = 81/195 (41%), Gaps = 36/195 (18%)
Query: 19 QQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSE-----WKTR------------ 61
QQ+ +VRK + L + E +++E L + + E WK R
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPD 1350
Query: 62 ---YETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEE 118
Y L + K+I L E++ ++ + +S+ + + ++SL L ++ E
Sbjct: 1351 TEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNL-IQSLKEDLNKVRTE 1409
Query: 119 KKTLESQVKYYALKLEQESKA--------------YQKINNERRTYLAEMSQGSGLHQVS 164
K+T++ + + ++++ K Y+++ ++ + +Q SG HQ
Sbjct: 1410 KETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQ-E 1468
Query: 165 KRQQVDQLPRMQENL 179
+ V ++ ++E L
Sbjct: 1469 QHVSVQEMQELKETL 1483
Score = 29.3 bits (64), Expect = 2.6
Identities = 19/74 (25%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 109 NTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQ 168
N L++L+E+ L SQ + +L+ SK Y+ + + Y E+ + LH+ + Q+
Sbjct: 694 NEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREI---TSLHE--RNQK 748
Query: 169 VDQLPRMQENLVKT 182
+ + QE ++ T
Sbjct: 749 LTATTQKQEQIINT 762
Score = 28.5 bits (62), Expect = 4.5
Identities = 32/126 (25%), Positives = 52/126 (41%), Gaps = 13/126 (10%)
Query: 21 LLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELEKQIVYLK 80
LL ++K A+ LS EL A G + Y +E D+L L
Sbjct: 359 LLSATKRKGAI-LSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQL------LL 411
Query: 81 EKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAY 140
EK+E + R++ VE+ +LK+ EE + + V ++KLEQ K
Sbjct: 412 EKLE------NKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEI 465
Query: 141 QKINNE 146
Q++ +
Sbjct: 466 QRLQED 471
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.336
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,425,658
Number of Sequences: 37866
Number of extensions: 310991
Number of successful extensions: 2593
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 477
Number of HSP's that attempted gapping in prelim test: 1857
Number of HSP's gapped (non-prelim): 1091
length of query: 214
length of database: 18,247,518
effective HSP length: 98
effective length of query: 116
effective length of database: 14,536,650
effective search space: 1686251400
effective search space used: 1686251400
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.