BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|222352151 poly(rC) binding protein 1 [Homo sapiens] (356 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 702 0.0 gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 575 e-164 gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 569 e-162 gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 565 e-161 gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 558 e-159 gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 541 e-154 gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 531 e-151 gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 495 e-140 gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 423 e-118 gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 390 e-108 gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 325 4e-89 gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 325 4e-89 gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 238 6e-63 gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 139 5e-33 gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 138 9e-33 gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 138 9e-33 gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 82 7e-16 gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 82 7e-16 gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 82 7e-16 gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 82 1e-15 gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 79 6e-15 gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 76 4e-14 gi|17402900 far upstream element-binding protein [Homo sapiens] 76 5e-14 gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 75 9e-14 gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 73 3e-13 gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 72 8e-13 gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 71 1e-12 gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 57 3e-08 gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 57 3e-08 gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 57 3e-08 >gi|222352151 poly(rC) binding protein 1 [Homo sapiens] Length = 356 Score = 702 bits (1813), Expect = 0.0 Identities = 356/356 (100%), Positives = 356/356 (100%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 Query: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ Sbjct: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240 Query: 241 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGA 300 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGA Sbjct: 241 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGA 300 Query: 301 NINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKGMGCS 356 NINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKGMGCS Sbjct: 301 NINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKGMGCS 356 >gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] Length = 366 Score = 575 bits (1483), Expect = e-164 Identities = 304/367 (82%), Positives = 326/367 (88%), Gaps = 12/367 (3%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLETLSQSP + +T Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP-KGVT 179 Query: 181 IPYQPMPASSPVICAGGQDRC---SDAAGYPHAT------HDLEGPPLDAYSIQGQHTIS 231 IPY+P P+SSPVI AGGQDR SD+A +PH T DLEGPPL+AY+IQGQ+ I Sbjct: 180 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 239 Query: 232 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL 290 DL KL+Q+A QQSHF M HG TGF+GI+SSSPEVKGYWA LDAS QTT HELTIPN+L Sbjct: 240 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDL 299 Query: 291 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE 350 IGCIIGRQGA INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE Sbjct: 300 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 359 Query: 351 K-GMGCS 356 GMG S Sbjct: 360 TGGMGSS 366 >gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] Length = 365 Score = 569 bits (1467), Expect = e-162 Identities = 303/367 (82%), Positives = 325/367 (88%), Gaps = 13/367 (3%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLETLSQSP + +T Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP-KGVT 179 Query: 181 IPYQPMPASSPVICAGGQDRC---SDAAGYPHAT------HDLEGPPLDAYSIQGQHTIS 231 IPY+P P+SSPVI AGGQDR SD+A +PH T DLEGPPL+AY+IQGQ+ I Sbjct: 180 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 239 Query: 232 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL 290 DL KL+Q+A QQSHF M HG TGF+GI+SSSPEVKGYW LDAS QTT HELTIPN+L Sbjct: 240 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDL 298 Query: 291 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE 350 IGCIIGRQGA INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE Sbjct: 299 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 358 Query: 351 K-GMGCS 356 GMG S Sbjct: 359 TGGMGSS 365 >gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] Length = 362 Score = 565 bits (1455), Expect = e-161 Identities = 300/367 (81%), Positives = 323/367 (88%), Gaps = 16/367 (4%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLE+ P+G +T Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 175 Query: 181 IPYQPMPASSPVICAGGQDRC---SDAAGYPHAT------HDLEGPPLDAYSIQGQHTIS 231 IPY+P P+SSPVI AGGQDR SD+A +PH T DLEGPPL+AY+IQGQ+ I Sbjct: 176 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 235 Query: 232 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL 290 DL KL+Q+A QQSHF M HG TGF+GI+SSSPEVKGYWA LDAS QTT HELTIPN+L Sbjct: 236 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDL 295 Query: 291 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE 350 IGCIIGRQGA INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE Sbjct: 296 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 355 Query: 351 K-GMGCS 356 GMG S Sbjct: 356 TGGMGSS 362 >gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] Length = 361 Score = 558 bits (1439), Expect = e-159 Identities = 299/367 (81%), Positives = 322/367 (87%), Gaps = 17/367 (4%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLE+ P+G +T Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 175 Query: 181 IPYQPMPASSPVICAGGQDRC---SDAAGYPHAT------HDLEGPPLDAYSIQGQHTIS 231 IPY+P P+SSPVI AGGQDR SD+A +PH T DLEGPPL+AY+IQGQ+ I Sbjct: 176 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 235 Query: 232 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL 290 DL KL+Q+A QQSHF M HG TGF+GI+SSSPEVKGYW LDAS QTT HELTIPN+L Sbjct: 236 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDL 294 Query: 291 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE 350 IGCIIGRQGA INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE Sbjct: 295 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 354 Query: 351 K-GMGCS 356 GMG S Sbjct: 355 TGGMGSS 361 >gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] Length = 335 Score = 541 bits (1395), Expect = e-154 Identities = 289/358 (80%), Positives = 308/358 (86%), Gaps = 25/358 (6%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLETLSQSP + +T Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP-KGVT 179 Query: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240 IPY+P P+SSPVI AGGQ AY+IQGQ+ I DL KL+Q Sbjct: 180 IPYRPKPSSSPVIFAGGQ----------------------AYTIQGQYAIPQPDLTKLHQ 217 Query: 241 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNLIGCIIGRQG 299 +A QQSHF M HG TGF+GI+SSSPEVKGYWA LDAS QTT HELTIPN+LIGCIIGRQG Sbjct: 218 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQG 277 Query: 300 ANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK-GMGCS 356 A INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE GMG S Sbjct: 278 AKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 335 >gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] Length = 331 Score = 531 bits (1367), Expect = e-151 Identities = 285/358 (79%), Positives = 305/358 (85%), Gaps = 29/358 (8%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLE+ P+G +T Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 175 Query: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240 IPY+P P+SSPVI AGGQ AY+IQGQ+ I DL KL+Q Sbjct: 176 IPYRPKPSSSPVIFAGGQ----------------------AYTIQGQYAIPQPDLTKLHQ 213 Query: 241 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNLIGCIIGRQG 299 +A QQSHF M HG TGF+GI+SSSPEVKGYWA LDAS QTT HELTIPN+LIGCIIGRQG Sbjct: 214 LAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQG 273 Query: 300 ANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK-GMGCS 356 A INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE GMG S Sbjct: 274 AKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 331 >gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] Length = 318 Score = 495 bits (1274), Expect = e-140 Identities = 273/358 (76%), Positives = 292/358 (81%), Gaps = 42/358 (11%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLE+ P+G +T Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLES---PPKG--VT 175 Query: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240 IPY+P P+SSPVI AGGQ AY+IQGQ+ I DL KL+Q Sbjct: 176 IPYRPKPSSSPVIFAGGQ----------------------AYTIQGQYAIPQPDLTKLHQ 213 Query: 241 VARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNLIGCIIGRQG 299 +A QQSHF M HG TGF+ A LDAS QTT HELTIPN+LIGCIIGRQG Sbjct: 214 LAMQQSHFPMTHGNTGFS-------------AGLDASAQTTSHELTIPNDLIGCIIGRQG 260 Query: 300 ANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK-GMGCS 356 A INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE GMG S Sbjct: 261 AKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS 318 >gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] Length = 371 Score = 423 bits (1088), Expect = e-118 Identities = 239/364 (65%), Positives = 277/364 (76%), Gaps = 37/364 (10%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 M++ V+E GLNVTLTIRLLMHGKEVGSIIGKKGE+VK++REESGARINISEGNCPERI+T Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 +TGPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPA+QCGSLIGKGG KI Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERA+TI+G P ++ +CVKQIC+VMLE+ P+G T Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLES---PPKG--AT 207 Query: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTI-SPLDLAKLN 239 IPY+P PAS+PVI AGGQ AY+IQGQ+ I P L KL+ Sbjct: 208 IPYRPKPASTPVIFAGGQ----------------------AYTIQGQYAIPHPDQLTKLH 245 Query: 240 QVARQQSHFAMM-HGGTGFAG------IDSSSPEVKGYWASLDAS-TQTTHELTIPNNLI 291 Q+A QQ+ F + F G + + G + LDAS +THELTIPN+LI Sbjct: 246 QLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLI 305 Query: 292 GCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE- 350 GCIIGRQG INEIRQMSGAQIKIAN EGSS RQ+TITG+ A+ISLAQYLINARL+SE Sbjct: 306 GCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEV 365 Query: 351 KGMG 354 GMG Sbjct: 366 TGMG 369 >gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] Length = 345 Score = 390 bits (1002), Expect = e-108 Identities = 222/363 (61%), Positives = 256/363 (70%), Gaps = 61/363 (16%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 M++ V+E GLNVTLTIRLLMHGKEVGSIIGKKGE+VK++REESGARINISEGNCPERI+T Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 +TGPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPA+QCGSLIGKGG KI Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRESTGAQVQVAGDMLPNSTERA+TI+G P ++ +CVKQIC+VMLE Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE------------ 200 Query: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQ 240 AY+IQGQ+ I DL KL+Q Sbjct: 201 ----------------------------------------AYTIQGQYAIPHPDLTKLHQ 220 Query: 241 VARQQSHFAMM-HGGTGFAG------IDSSSPEVKGYWASLDAS-TQTTHELTIPNNLIG 292 +A QQ+ F + F G + + G + LDAS +THELTIPN+LIG Sbjct: 221 LAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIG 280 Query: 293 CIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE-K 351 CIIGRQG INEIRQMSGAQIKIAN EGSS RQ+TITG+ A+ISLAQYLINARL+SE Sbjct: 281 CIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEVT 340 Query: 352 GMG 354 GMG Sbjct: 341 GMG 343 Score = 37.7 bits (86), Expect = 0.016 Identities = 25/67 (37%), Positives = 38/67 (56%), Gaps = 4/67 (5%) Query: 25 VGSIIGKKGESVKRIREESGARI---NISEGNCPERIITLTGPTNAIFKAFAMIIDKLEE 81 +G IIG++G + IR+ SGA+I N +EG+ ER IT+TG I A +I +L Sbjct: 279 IGCIIGRQGTKINEIRQMSGAQIKIANATEGS-SERQITITGTPANISLAQYLINARLTS 337 Query: 82 DINSSMT 88 ++ T Sbjct: 338 EVTGMGT 344 >gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] Length = 403 Score = 325 bits (833), Expect = 4e-89 Identities = 186/353 (52%), Positives = 236/353 (66%), Gaps = 47/353 (13%) Query: 2 DAGVTESG-LNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 D G+ E L++TLT+R+LMHGKEVGSIIGKKGE+VKRIRE+S ARI ISEG+CPERI T Sbjct: 5 DGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITT 64 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 +TG T A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PA+QCGSLIGK G KI Sbjct: 65 ITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKI 124 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRE+TGAQVQVAGD+LPNSTERA+T++GVP ++ CV+QIC V+LE+ P+G T Sbjct: 125 KEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILES---PPKG--AT 179 Query: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQH-TISPLDLAKLN 239 IPY P + V+ + Q +S+QGQ+ ++P ++ KL Sbjct: 180 IPYHPSLSLGTVLLSANQ----------------------GFSVQGQYGAVTPAEVTKLQ 217 Query: 240 QVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQT-THELTIPNNLIGCIIGRQ 298 Q++ FA +P V LD TQT + E +PN+LIGC+IGRQ Sbjct: 218 QLSSHAVPFA--------------TPSVV---PGLDPGTQTSSQEFLVPNDLIGCVIGRQ 260 Query: 299 GANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK 351 G+ I+EIRQMSGA IKI N EG+ R VTITGS SI+LAQYLI A L + K Sbjct: 261 GSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAK 313 >gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] Length = 403 Score = 325 bits (833), Expect = 4e-89 Identities = 186/353 (52%), Positives = 236/353 (66%), Gaps = 47/353 (13%) Query: 2 DAGVTESG-LNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60 D G+ E L++TLT+R+LMHGKEVGSIIGKKGE+VKRIRE+S ARI ISEG+CPERI T Sbjct: 5 DGGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITT 64 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 +TG T A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PA+QCGSLIGK G KI Sbjct: 65 ITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKI 124 Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180 KEIRE+TGAQVQVAGD+LPNSTERA+T++GVP ++ CV+QIC V+LE+ P+G T Sbjct: 125 KEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILES---PPKG--AT 179 Query: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQH-TISPLDLAKLN 239 IPY P + V+ + Q +S+QGQ+ ++P ++ KL Sbjct: 180 IPYHPSLSLGTVLLSANQ----------------------GFSVQGQYGAVTPAEVTKLQ 217 Query: 240 QVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQT-THELTIPNNLIGCIIGRQ 298 Q++ FA +P V LD TQT + E +PN+LIGC+IGRQ Sbjct: 218 QLSSHAVPFA--------------TPSVV---PGLDPGTQTSSQEFLVPNDLIGCVIGRQ 260 Query: 299 GANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK 351 G+ I+EIRQMSGA IKI N EG+ R VTITGS SI+LAQYLI A L + K Sbjct: 261 GSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAK 313 >gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] Length = 424 Score = 238 bits (607), Expect = 6e-63 Identities = 154/367 (41%), Positives = 200/367 (54%), Gaps = 101/367 (27%) Query: 42 ESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLR 101 +S ARI ISEG+CPERI T+TG T A+F A +MI KL+ED+ ++ N SRPPVTLR Sbjct: 12 QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 71 Query: 102 LVVPATQCGSLIGKGGCKIK---EIR---------------------------------- 124 LV+PA+QCGSLIGK G KIK E+R Sbjct: 72 LVIPASQCGSLIGKAGTKIKEIREVRGEIYHPQGIRGKGAVVRGVLGLWRPPHLESSEPG 131 Query: 125 ------------------ESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVM 166 ++TGAQVQVAGD+LPNSTERA+T++GVP ++ CV+QIC V+ Sbjct: 132 QPFSGLWEQPEVAPVLCLQTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 191 Query: 167 LETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQG 226 LE+ P+G TIPY P + V+ + Q +S+QG Sbjct: 192 LES---PPKGA--TIPYHPSLSLGTVLLSANQ----------------------GFSVQG 224 Query: 227 QH-TISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HEL 284 Q+ ++P ++ KL Q++ FA +P V LD TQT+ E Sbjct: 225 QYGAVTPAEVTKLQQLSSHAVPFA--------------TPSVV---PGLDPGTQTSSQEF 267 Query: 285 TIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLIN 344 +PN+LIGC+IGRQG+ I+EIRQMSGA IKI N EG+ R VTITGS SI+LAQYLI Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLIT 327 Query: 345 ARLSSEK 351 A L + K Sbjct: 328 ACLETAK 334 Score = 47.4 bits (111), Expect = 2e-05 Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Query: 103 VVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQI 162 +VP G +IG+ G KI EIR+ +GA +++ G+ + ER +TI G P S+ + + Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQAEGAGERHVTITGSPVSIA-LAQYL 325 Query: 163 CLVMLETLSQSPQGRVMTIPYQ-PMPASSPV 192 LET + G + P P P S P+ Sbjct: 326 ITACLETAKSTSGGTPSSAPADLPAPFSPPL 356 Score = 36.6 bits (83), Expect = 0.035 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 6/75 (8%) Query: 25 VGSIIGKKGESVKRIREESGARINI---SEGNCPERIITLTGPTNAIFKAFAMIIDKLEE 81 +G +IG++G + IR+ SGA I I +EG ER +T+TG +I A +I LE Sbjct: 274 IGCVIGRQGSKISEIRQMSGAHIKIGNQAEG-AGERHVTITGSPVSIALAQYLITACLE- 331 Query: 82 DINSSMTNSTAASRP 96 S + T +S P Sbjct: 332 -TAKSTSGGTPSSAP 345 >gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b [Homo sapiens] Length = 463 Score = 139 bits (349), Expect = 5e-33 Identities = 121/425 (28%), Positives = 187/425 (44%), Gaps = 97/425 (22%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMI 75 +R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104 Query: 76 IDKLEEDINSSMTNSTAASRPPVT--------------------LRLVVPATQCGSLIGK 115 I LEE + + + TA S+ P+ LRL++ + G +IG Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162 Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSP- 174 G KIKE+RE+T +++ + P+ST+R + I G P V EC+K ++L+ +S+SP Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218 Query: 175 QGRVMTIPYQP---------------------MPASSPVICAGGQDRCSDAAG---YPHA 210 +GR PY P P P+ GG DR G P + Sbjct: 219 KGRAQ--PYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPS 276 Query: 211 THDLE------GPPLDAYSIQGQHTIS----PL---------DLAKLNQVARQQSHFAMM 251 D + GPP G+ PL DL ++ R + M Sbjct: 277 RRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGM 336 Query: 252 HG----GTGFAGIDSSSPEV--------------------KGYWASLDASTQTTHELTIP 287 G T + ID+ SP +G + L TT ++TIP Sbjct: 337 VGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT-QVTIP 395 Query: 288 NNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARL 347 +L G IIG+ G I +IR SGA IKI P+EGS R +TITG+ I AQYL+ + Sbjct: 396 KDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSV 455 Query: 348 SSEKG 352 G Sbjct: 456 KQYSG 460 Score = 45.1 bits (105), Expect = 1e-04 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPT 65 G + +RLL+H G IIG KG +K +RE + I + + CP +R++ + G Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199 Query: 66 NAIFKAFAMIIDKLEE 81 + + + +I+D + E Sbjct: 200 DRVVECIKIILDLISE 215 Score = 38.9 bits (89), Expect = 0.007 Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 3/73 (4%) Query: 98 VTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTE 157 V LR+++ + G++IGKGG IK +R A V V P ER ++I+ +++ E Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99 Query: 158 CVKQICLVMLETL 170 +K+I + E L Sbjct: 100 ILKKIIPTLEEGL 112 >gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a [Homo sapiens] Length = 464 Score = 138 bits (347), Expect = 9e-33 Identities = 120/416 (28%), Positives = 185/416 (44%), Gaps = 97/416 (23%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMI 75 +R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104 Query: 76 IDKLEEDINSSMTNSTAASRPPVT--------------------LRLVVPATQCGSLIGK 115 I LEE + + + TA S+ P+ LRL++ + G +IG Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162 Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSP- 174 G KIKE+RE+T +++ + P+ST+R + I G P V EC+K ++L+ +S+SP Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218 Query: 175 QGRVMTIPYQP---------------------MPASSPVICAGGQDRCSDAAG---YPHA 210 +GR PY P P P+ GG DR G P + Sbjct: 219 KGRAQ--PYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPS 276 Query: 211 THDLE------GPPLDAYSIQGQHTIS----PL---------DLAKLNQVARQQSHFAMM 251 D + GPP G+ PL DL ++ R + M Sbjct: 277 RRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGM 336 Query: 252 HG----GTGFAGIDSSSPEV--------------------KGYWASLDASTQTTHELTIP 287 G T + ID+ SP +G + L TT ++TIP Sbjct: 337 VGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT-QVTIP 395 Query: 288 NNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLI 343 +L G IIG+ G I +IR SGA IKI P+EGS R +TITG+ I AQYL+ Sbjct: 396 KDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451 Score = 45.1 bits (105), Expect = 1e-04 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPT 65 G + +RLL+H G IIG KG +K +RE + I + + CP +R++ + G Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199 Query: 66 NAIFKAFAMIIDKLEE 81 + + + +I+D + E Sbjct: 200 DRVVECIKIILDLISE 215 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%) Query: 26 GSIIGKKGESVKRIREESGARINISE--GNCPERIITLTGPTNAIFKAFAMIIDKLEE 81 GSIIGK G+ +K+IR ESGA I I E +RIIT+TG + I A ++ + +++ Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457 Score = 38.9 bits (89), Expect = 0.007 Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 3/73 (4%) Query: 98 VTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTE 157 V LR+++ + G++IGKGG IK +R A V V P ER ++I+ +++ E Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99 Query: 158 CVKQICLVMLETL 170 +K+I + E L Sbjct: 100 ILKKIIPTLEEGL 112 >gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a [Homo sapiens] Length = 464 Score = 138 bits (347), Expect = 9e-33 Identities = 120/416 (28%), Positives = 185/416 (44%), Gaps = 97/416 (23%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMI 75 +R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104 Query: 76 IDKLEEDINSSMTNSTAASRPPVT--------------------LRLVVPATQCGSLIGK 115 I LEE + + + TA S+ P+ LRL++ + G +IG Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162 Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSP- 174 G KIKE+RE+T +++ + P+ST+R + I G P V EC+K ++L+ +S+SP Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218 Query: 175 QGRVMTIPYQP---------------------MPASSPVICAGGQDRCSDAAG---YPHA 210 +GR PY P P P+ GG DR G P + Sbjct: 219 KGRAQ--PYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPS 276 Query: 211 THDLE------GPPLDAYSIQGQHTIS----PL---------DLAKLNQVARQQSHFAMM 251 D + GPP G+ PL DL ++ R + M Sbjct: 277 RRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGM 336 Query: 252 HG----GTGFAGIDSSSPEV--------------------KGYWASLDASTQTTHELTIP 287 G T + ID+ SP +G + L TT ++TIP Sbjct: 337 VGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITT-QVTIP 395 Query: 288 NNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLI 343 +L G IIG+ G I +IR SGA IKI P+EGS R +TITG+ I AQYL+ Sbjct: 396 KDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451 Score = 45.1 bits (105), Expect = 1e-04 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPT 65 G + +RLL+H G IIG KG +K +RE + I + + CP +R++ + G Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199 Query: 66 NAIFKAFAMIIDKLEE 81 + + + +I+D + E Sbjct: 200 DRVVECIKIILDLISE 215 Score = 44.3 bits (103), Expect = 2e-04 Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 2/58 (3%) Query: 26 GSIIGKKGESVKRIREESGARINISE--GNCPERIITLTGPTNAIFKAFAMIIDKLEE 81 GSIIGK G+ +K+IR ESGA I I E +RIIT+TG + I A ++ + +++ Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457 Score = 38.9 bits (89), Expect = 0.007 Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 3/73 (4%) Query: 98 VTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTE 157 V LR+++ + G++IGKGG IK +R A V V P ER ++I+ +++ E Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99 Query: 158 CVKQICLVMLETL 170 +K+I + E L Sbjct: 100 ILKKIIPTLEEGL 112 >gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo sapiens] Length = 507 Score = 82.0 bits (201), Expect = 7e-16 Identities = 87/360 (24%), Positives = 147/360 (40%), Gaps = 57/360 (15%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEG----NCPERIITLTGPTNAIFKA 71 +++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA Sbjct: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233 Query: 72 FAMIIDKLEE-------------DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGC 118 +II K++E ++ + NS P V+P + + G Sbjct: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 292 Query: 119 KIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRV 178 + + G+ L T T+A + L TL Sbjct: 293 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYN------------LNTLG------- 333 Query: 179 MTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKL 238 + A+ + A + AA AT+ E S G L Sbjct: 334 --LGLSQAAATGALAAAAASANPAAAAANLLATYASEA------SASGSTAGGTAGTFAL 385 Query: 239 NQVARQQSHFAMMHGGTGFAGIDS--SSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296 +A A G+ G S ++ + G S D S E+ +P NL+G I+G Sbjct: 386 GSLA------AATAATNGYFGAASPLAASAILGTEKSTDGSKDVV-EIAVPENLVGAILG 438 Query: 297 RQGANINEIRQMSGAQIKIANP---VEGSSGRQVTITGSAASISLAQYLINARLSSEKGM 353 + G + E ++++GA+I+I+ V G+ R+VTITG+ A+ AQYLI R++ E+G+ Sbjct: 439 KGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGV 498 Score = 70.9 bits (172), Expect = 2e-12 Identities = 57/231 (24%), Positives = 110/231 (47%), Gaps = 50/231 (21%) Query: 6 TESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CPERIIT 60 T +G + +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ Sbjct: 42 TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL 101 Query: 61 LTGPTNAIFKAFAMIIDKLEE---------------------------DINSSMTNSTAA 93 + G A+ I +K+ E + SS T + ++ Sbjct: 102 IQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSS 161 Query: 94 SRPPVT------LRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERA 145 P+T ++++VP + G +IGKGG +K + E +GA VQ++ D + N ER Sbjct: 162 PSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERV 220 Query: 146 ITIAGVPQSVTECVKQICLVMLETLSQSPQ-GRVMTIPYQ----PMPASSP 191 +T++G P+ + V+ ++++ + + PQ G + I Y P+ S+P Sbjct: 221 VTVSGEPEQNRKAVE----LIIQKIQEDPQSGSCLNISYANVTGPVANSNP 267 Score = 57.0 bits (136), Expect = 3e-08 Identities = 56/259 (21%), Positives = 102/259 (39%), Gaps = 66/259 (25%) Query: 100 LRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAG--DMLPNSTERAITIAGVPQSVTE 157 L++++P+ GS+IGKGG I ++++ TGA ++++ D P +TER I G E Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGT----VE 107 Query: 158 CVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGP 217 + + + E + + PQ T P + + V DR P + + Sbjct: 108 ALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTV----NPDRIKQTL--PSSPTTTKSS 161 Query: 218 PLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDAS 277 P D P+ ++ NQV Sbjct: 162 PSD-----------PMTTSRANQV------------------------------------ 174 Query: 278 TQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS--GRQVTITGSAAS 335 ++ +PN+ G IIG+ GA + + + SGA ++++ +G + R VT++G Sbjct: 175 -----KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQ 229 Query: 336 ISLAQYLINARLSSEKGMG 354 A LI ++ + G Sbjct: 230 NRKAVELIIQKIQEDPQSG 248 >gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo sapiens] Length = 483 Score = 82.0 bits (201), Expect = 7e-16 Identities = 87/360 (24%), Positives = 147/360 (40%), Gaps = 57/360 (15%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEG----NCPERIITLTGPTNAIFKA 71 +++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA Sbjct: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 Query: 72 FAMIIDKLEE-------------DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGC 118 +II K++E ++ + NS P V+P + + G Sbjct: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 268 Query: 119 KIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRV 178 + + G+ L T T+A + L TL Sbjct: 269 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYN------------LNTLG------- 309 Query: 179 MTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKL 238 + A+ + A + AA AT+ E S G L Sbjct: 310 --LGLSQAAATGALAAAAASANPAAAAANLLATYASEA------SASGSTAGGTAGTFAL 361 Query: 239 NQVARQQSHFAMMHGGTGFAGIDS--SSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296 +A A G+ G S ++ + G S D S E+ +P NL+G I+G Sbjct: 362 GSLA------AATAATNGYFGAASPLAASAILGTEKSTDGSKDVV-EIAVPENLVGAILG 414 Query: 297 RQGANINEIRQMSGAQIKIANP---VEGSSGRQVTITGSAASISLAQYLINARLSSEKGM 353 + G + E ++++GA+I+I+ V G+ R+VTITG+ A+ AQYLI R++ E+G+ Sbjct: 415 KGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGV 474 Score = 77.0 bits (188), Expect = 2e-14 Identities = 56/207 (27%), Positives = 107/207 (51%), Gaps = 26/207 (12%) Query: 6 TESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CPERIIT 60 T +G + +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ Sbjct: 42 TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL 101 Query: 61 LTGPTNAIFKAFAMIIDKLEE-DINSSMTNSTAASRPPVTL--------RLVVPATQCGS 111 + G A+ I +K+ E N + T + +P T+ +++VP + G Sbjct: 102 IQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGL 161 Query: 112 LIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIAGVPQSVTECVKQICLVMLET 169 +IGKGG +K + E +GA VQ++ D + N ER +T++G P+ + V+ ++++ Sbjct: 162 IIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQNRKAVE----LIIQK 216 Query: 170 LSQSPQ-GRVMTIPYQ----PMPASSP 191 + + PQ G + I Y P+ S+P Sbjct: 217 IQEDPQSGSCLNISYANVTGPVANSNP 243 Score = 37.7 bits (86), Expect = 0.016 Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS--GRQVTITGSAASISLAQ 340 ++ +PN+ G IIG+ GA + + + SGA ++++ +G + R VT++G A Sbjct: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210 Query: 341 YLINARLSSEKGMG 354 LI ++ + G Sbjct: 211 ELIIQKIQEDPQSG 224 Score = 30.0 bits (66), Expect = 3.3 Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Query: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVE---GSSGRQVTITGSAASISLA 339 ++ IP+ G IIG+ G I ++++ +GA IK++ + G++ R I G+ +++ Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112 Query: 340 QYLINARL 347 I ++ Sbjct: 113 HGFIAEKI 120 >gi|154355000 KH-type splicing regulatory protein [Homo sapiens] Length = 711 Score = 82.0 bits (201), Expect = 7e-16 Identities = 89/350 (25%), Positives = 149/350 (42%), Gaps = 37/350 (10%) Query: 25 VGSIIGKKGESVKRIREESGARINIS--EGNCPERIITLTGPTNAIFKAFAMIIDKLEED 82 VG IIG+ GE + +I+++SG ++ IS G PER ++LTG ++ KA M+ D + Sbjct: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215 Query: 83 INS---SMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139 ++ + +++PA + G +IGKGG IK+++E G ++ + D Sbjct: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275 Query: 140 N-STERAITIAGVPQSVTECVKQICLVMLETLSQSPQG----------RVMTIPYQPMPA 188 N + ++ + I G P V+Q C ++++ L + QG R+ P+P Sbjct: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPR 331 Query: 189 SSPVICAGGQ----DRCSDAAG--YPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVA 242 S + G + + AG D GP A H + P D + Sbjct: 332 HSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIA------HIMGPPDRCEHAARI 385 Query: 243 RQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELT--IPNNLIGCIIGRQGA 300 ++ G G G P +G E+T IP + G +IGR G Sbjct: 386 INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGE 445 Query: 301 NINEIRQMSGAQIKIAN--PVEGSSG-RQVTITGSAASISLAQYLINARL 347 N+ I Q +GA ++I+ P G + I GS I A+ LI ++ Sbjct: 446 NVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495 Score = 67.8 bits (164), Expect = 1e-11 Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 29/222 (13%) Query: 25 VGSIIGKKGESVKRIREESGARINISE--GNCPERIITLTGPTNAIFKAFAMIIDKLEED 82 VG +IG+ GE +K+I+ ++G RI + G PE+I + GP + A +I D L+ Sbjct: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393 Query: 83 INSSMTNSTAASRPPV----------------TLRLVVPATQCGSLIGKGGCKIKEIRES 126 + PP + +P +CG +IG+GG +K I + Sbjct: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453 Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQ 184 TGA V+++ + PN + I G PQ + + ++E + P V P Sbjct: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQ-----LIEEKIEGPLCPVGPGPGG 508 Query: 185 PMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQG 226 P PA G PHA GPP Y QG Sbjct: 509 PGPAGPMGPFNPGPFNQGPPGAPPHA----GGPPPHQYPPQG 546 Score = 53.9 bits (128), Expect = 2e-07 Identities = 26/75 (34%), Positives = 46/75 (61%) Query: 278 TQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASIS 337 T T E +P+ ++G IIGR G IN+I+Q SG +++I+ G R V++TG+ S+ Sbjct: 143 TSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQ 202 Query: 338 LAQYLINARLSSEKG 352 A+ +++ +S +G Sbjct: 203 KAKMMLDDIVSRGRG 217 Score = 52.8 bits (125), Expect = 5e-07 Identities = 51/197 (25%), Positives = 89/197 (45%), Gaps = 18/197 (9%) Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI----SEGNCPERIITLTGP 64 G N T+ ++ GK G +IGK GE++K+++E +G ++ + S+ ++ + + G Sbjct: 230 GQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGD 288 Query: 65 TNAIFKAFAMIIDKL-EEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEI 123 + +A M++D L E D + SR + + VP G +IG+ G IK+I Sbjct: 289 PYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKI 348 Query: 124 RESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPY 183 + G ++Q D E+ I G P E +I +L++L P G Sbjct: 349 QNDAGVRIQFKQDD-GTGPEKIAHIMGPPDR-CEHAARIINDLLQSLRSGPPG------- 399 Query: 184 QPMPASSPVICAGGQDR 200 P P + GG+ R Sbjct: 400 ---PPGGPGMPPGGRGR 413 Score = 43.1 bits (100), Expect = 4e-04 Identities = 63/287 (21%), Positives = 109/287 (37%), Gaps = 40/287 (13%) Query: 81 EDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138 + I+S + R +T VP G +IG+GG +I +I++ +G +VQ++ D L Sbjct: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187 Query: 139 PNSTERAITIAGVPQSVTECVKQICLVMLETLSQSP--------QGRVMTIPYQPMPASS 190 P ER++++ G P+SV + + ++ P G+ T+ +PA Sbjct: 188 P---ERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGK 244 Query: 191 P--VICAGGQ--DRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPL----DLAKLNQVA 242 VI GG+ + + AG L Q + PL D K+ Q Sbjct: 245 AGLVIGKGGETIKQLQERAGVKMI--------LIQDGSQNTNVDKPLRIIGDPYKVQQAC 296 Query: 243 RQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANI 302 GF + + G ++ +P + +G +IGR G I Sbjct: 297 EMVMDILRERDQGGFGDRNEYGSRIGG-----------GIDVPVPRHSVGVVIGRSGEMI 345 Query: 303 NEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSS 349 +I+ +G +I+ + I G A +IN L S Sbjct: 346 KKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQS 392 >gi|100816392 far upstream element (FUSE) binding protein 3 [Homo sapiens] Length = 572 Score = 81.6 bits (200), Expect = 1e-15 Identities = 91/354 (25%), Positives = 144/354 (40%), Gaps = 44/354 (12%) Query: 23 KEVGSIIGKKGESVKRIREESGARINISE--GNCPERIITLTGPTNAIFKAFAMIIDKLE 80 K VG IIG+ GE + RI+ ESG +I I+ PER LTG +I +A ++ ++ Sbjct: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146 Query: 81 EDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQ-VQVAGDMLP 139 N ++ S + +++PA++ G +IG+GG IK+++E TG + V + LP Sbjct: 147 RCRNGPGFHNDIDSNSTIQ-EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLP 205 Query: 140 NSTERAITIAGVPQSVTECVKQICLVMLETLS----------QSPQGRVMTIPYQPMPAS 189 ++ + I G V + + + ++ E S G P A Sbjct: 206 TGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAV 265 Query: 190 SPVICAGGQ--DRCSDAAGY-----------PHATHDLEGPPLDAYSIQGQHTISPLDLA 236 VI G+ + + AG P + GPP H IS L L Sbjct: 266 GIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQ--HAAHIISELILT 323 Query: 237 KLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296 A G G +G W+ T+P + G +IG Sbjct: 324 ------------AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIG 371 Query: 297 RQGANINEIRQMSGAQIKI-ANPVEGSSG--RQVTITGSAASISLAQYLINARL 347 + G NI I Q SGA +++ NP S R+ TI G I +A+ LI+ ++ Sbjct: 372 KGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425 Score = 73.9 bits (180), Expect = 2e-13 Identities = 74/248 (29%), Positives = 106/248 (42%), Gaps = 31/248 (12%) Query: 25 VGSIIGKKGESVKRIREESGARINIS--EGNCPERIITLTGPTNAIFKAFAMIIDKL--- 79 VG +IG+ GE +K+I+ ++G RI +G PER + GP + A A II +L Sbjct: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323 Query: 80 --EEDINSSMTN-----------STAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRES 126 E D + S A + VPA +CG +IGKGG IK I + Sbjct: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383 Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQ 184 +GA V++ + PNS R TI GVPQ + E +Q+ + + G P+ Sbjct: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQI-EVARQLIDEKVGGTNLGAPGAFGQSPFS 442 Query: 185 PMPAS------SPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKL 238 PA P + + G PH+T + GPP A+ QG + Sbjct: 443 QPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHST-PVSGPP--AFLTQGWGSTYQAWQQPT 499 Query: 239 NQVARQQS 246 QV QQS Sbjct: 500 QQVPSQQS 507 Score = 53.5 bits (127), Expect = 3e-07 Identities = 43/169 (25%), Positives = 80/169 (47%), Gaps = 27/169 (15%) Query: 18 LLMHGKEVGSIIGKKGESVKRIREESGAR-INISEGNCP---ERIITLTGPTNAIFKAFA 73 +L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + +TG + +A Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226 Query: 74 MIIDKLEE-----------DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKE 122 M+++ + E D NS M ++ + VP G +IG+ G IK+ Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGG--------SIEVSVPRFAVGIVIGRNGEMIKK 278 Query: 123 IRESTGAQVQVAGDMLPNSTERAITIAGVP---QSVTECVKQICLVMLE 168 I+ G ++Q D S ERA + G P Q + ++ L E Sbjct: 279 IQNDAGVRIQFKPDD-GISPERAAQVMGPPDRCQHAAHIISELILTAQE 326 Score = 48.1 bits (113), Expect = 1e-05 Identities = 25/66 (37%), Positives = 38/66 (57%) Query: 278 TQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASIS 337 T T E +P+ ++G IIGR G I+ I+ SG +I+IA+ G R +TG+ SI Sbjct: 76 TVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIE 135 Query: 338 LAQYLI 343 A+ L+ Sbjct: 136 QAKRLL 141 Score = 40.4 bits (93), Expect = 0.002 Identities = 58/260 (22%), Positives = 102/260 (39%), Gaps = 26/260 (10%) Query: 95 RPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQS 154 R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S Sbjct: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133 Query: 155 VTECVKQICLVMLETLSQSPQ-----GRVMTIPYQPMPASSP--VICAGGQ--DRCSDAA 205 + E K++ +++ P TI +PAS VI GG+ + + Sbjct: 134 I-EQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERT 192 Query: 206 GYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSP 265 G ++ PL + + D K+ Q F G+ Sbjct: 193 GVKMVM--IQDGPLPTGADKPLRITG--DAFKVQQAREMVLEIIREKDQADFRGVRGDFN 248 Query: 266 EVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEG-SSG 324 G + E+++P +G +IGR G I +I+ +G +I+ P +G S Sbjct: 249 SRMG---------GGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KPDDGISPE 298 Query: 325 RQVTITGSAASISLAQYLIN 344 R + G A ++I+ Sbjct: 299 RAAQVMGPPDRCQHAAHIIS 318 >gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 isoform a [Homo sapiens] Length = 599 Score = 79.0 bits (193), Expect = 6e-15 Identities = 86/359 (23%), Positives = 155/359 (43%), Gaps = 55/359 (15%) Query: 4 GVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGNCPERIIT 60 G T + +R+L+ + VG+IIGK+G ++K I +++ +R++I E+ +T Sbjct: 184 GGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVT 243 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 + +A MI++ ++++ + + + L+++ G LIGK G + Sbjct: 244 IHATPEGTSEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNL 297 Query: 121 KEIRESTGAQVQVAG--DMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRV 178 K+I TG ++ ++ D+ + ER IT+ G ++ +I ++ L ++ + + Sbjct: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEI----MKKLREAFENDM 353 Query: 179 MTIPYQP-----MPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPL 233 + + Q + S+ I + G S AG A PP Y H+ Sbjct: 354 LAVNQQANLIPGLNLSALGIFSTGLSVLSPPAGPRGA------PPAAPYHPFTTHS---- 403 Query: 234 DLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGC 293 +F+ ++ F P Y Q L IP +G Sbjct: 404 ------------GYFSSLYPHHQFGPF----PHHHSY------PEQEIVNLFIPTQAVGA 441 Query: 294 IIGRQGANINEIRQMSGAQIKIANPVEGS--SGRQVTITGSAASISLAQYLINARLSSE 350 IIG++GA+I ++ + +GA IKIA P EG S R V ITG + AQ I +L E Sbjct: 442 IIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499 Score = 76.3 bits (186), Expect = 4e-14 Identities = 54/168 (32%), Positives = 86/168 (51%), Gaps = 12/168 (7%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPTNAIFKAF 72 + L + + VG+IIGKKG +K++ +GA I I+ P ER++ +TGP A FKA Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489 Query: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQ 132 I KL+E+ + N + +R VP++ G +IGKGG + E++ T A+V Sbjct: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544 Query: 133 VAGDMLPNSTERAIT-IAG---VPQSVTECVKQICLVMLETLSQSPQG 176 V D P+ E I I G Q+ +++I + + + PQG Sbjct: 545 VPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQG 592 Score = 49.7 bits (117), Expect = 4e-06 Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 5/92 (5%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CP 55 M E+ L + +++L H VG +IGK+G ++K+I E+G +I IS P Sbjct: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321 Query: 56 ERIITLTGPTNAIFKAFAMIIDKLEEDINSSM 87 ER IT+ G A A I+ KL E + M Sbjct: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDM 353 Score = 43.1 bits (100), Expect = 4e-04 Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 2/101 (1%) Query: 100 LRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECV 159 + L +P G++IGK G IK++ GA +++A P+ +ER + I G P++ + Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489 Query: 160 KQICLVMLETLSQSPQGRVMTIPYQPMPASSP--VICAGGQ 198 +I + E +P+ V + +P+S+ VI GG+ Sbjct: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 530 Score = 28.5 bits (62), Expect = 9.6 Identities = 9/46 (19%), Positives = 25/46 (54%) Query: 284 LTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTI 329 + +P++ G +IG+ G +NE++ ++ A++ + +V + Sbjct: 514 IRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIV 559 >gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 isoform b [Homo sapiens] Length = 556 Score = 76.3 bits (186), Expect = 4e-14 Identities = 54/168 (32%), Positives = 86/168 (51%), Gaps = 12/168 (7%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPTNAIFKAF 72 + L + + VG+IIGKKG +K++ +GA I I+ P ER++ +TGP A FKA Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446 Query: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQ 132 I KL+E+ + N + +R VP++ G +IGKGG + E++ T A+V Sbjct: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501 Query: 133 VAGDMLPNSTERAIT-IAG---VPQSVTECVKQICLVMLETLSQSPQG 176 V D P+ E I I G Q+ +++I + + + PQG Sbjct: 502 VPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQG 549 Score = 72.4 bits (176), Expect = 6e-13 Identities = 62/226 (27%), Positives = 102/226 (45%), Gaps = 28/226 (12%) Query: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNC-----P 55 M E+ L + +++L H VG +IGK+G ++K+I E+G +I IS P Sbjct: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321 Query: 56 ERIITLTGPTNAIFKAFAMIIDKLEEDINSSM----TNSTAASR---------------- 95 ER IT+ G A A I+ KL E + M T+S S Sbjct: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSY 381 Query: 96 -PPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQS 154 + L +P G++IGK G IK++ GA +++A P+ +ER + I G P++ Sbjct: 382 PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441 Query: 155 VTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSP--VICAGGQ 198 + +I + E +P+ V + +P+S+ VI GG+ Sbjct: 442 QFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 487 Score = 60.5 bits (145), Expect = 2e-09 Identities = 69/275 (25%), Positives = 117/275 (42%), Gaps = 38/275 (13%) Query: 100 LRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECV 159 LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ +E Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255 Query: 160 KQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQD-----RCSDAAGYPHATHDL 214 + I +M + ++ IP + + + V G++ + G L Sbjct: 256 RMILEIMQKEADETKLAE--EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313 Query: 215 EGPPLDAYS----IQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGY 270 + L Y+ I + T+ A++ + + + F +++ S GY Sbjct: 314 QD--LSIYNPERTITVKGTVEACASAEIEIMKKLREAFE-----NDMLAVNTHS----GY 362 Query: 271 WASL-------------DASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIAN 317 ++SL Q L IP +G IIG++GA+I ++ + +GA IKIA Sbjct: 363 FSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA- 421 Query: 318 PVEGS--SGRQVTITGSAASISLAQYLINARLSSE 350 P EG S R V ITG + AQ I +L E Sbjct: 422 PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 456 Score = 58.5 bits (140), Expect = 9e-09 Identities = 37/156 (23%), Positives = 79/156 (50%), Gaps = 11/156 (7%) Query: 4 GVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGNCPERIIT 60 G T + +R+L+ + VG+IIGK+G ++K I +++ +R++I E+ +T Sbjct: 184 GGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVT 243 Query: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120 + +A MI++ ++++ + + + L+++ G LIGK G + Sbjct: 244 IHATPEGTSEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNL 297 Query: 121 KEIRESTGAQVQVAG--DMLPNSTERAITIAGVPQS 154 K+I TG ++ ++ D+ + ER IT+ G ++ Sbjct: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEA 333 Score = 28.5 bits (62), Expect = 9.6 Identities = 9/46 (19%), Positives = 25/46 (54%) Query: 284 LTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTI 329 + +P++ G +IG+ G +NE++ ++ A++ + +V + Sbjct: 471 IRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIV 516 >gi|17402900 far upstream element-binding protein [Homo sapiens] Length = 644 Score = 75.9 bits (185), Expect = 5e-14 Identities = 90/354 (25%), Positives = 146/354 (41%), Gaps = 49/354 (13%) Query: 25 VGSIIGKKGESVKRIREESGARINIS--EGNCPERIITLTGPTNAIFKAFAMIIDKLEED 82 VG IIG+ GE + RI++ESG +I I+ G PER LTG ++ A ++D++ E Sbjct: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170 Query: 83 INSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141 + +++PA++ G +IGKGG IK+++E G ++ + D N+ Sbjct: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230 Query: 142 TERAITIAGVPQSVTECVKQICLVML-----------ETLSQSPQGRVMTIPYQPMPASS 190 ++ + I G P V + K++ L ++ E S+ + +P P A Sbjct: 231 ADKPLRITGDPYKVQQ-AKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVG 288 Query: 191 PVICAGGQ--DRCSDAAGY-----------PHATHDLEGPPLDAYSIQGQHTISPL-DLA 236 VI G+ + + AG P + GPP + QH + DL Sbjct: 289 IVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPP-----DRCQHAAEIITDLL 343 Query: 237 KLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296 + Q GG G G +G W +P G IIG Sbjct: 344 RSVQAGNP--------GGPGPGG--RGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIG 393 Query: 297 RQGANINEIRQMSGAQIKIAN---PVEGSSGRQVTITGSAASISLAQYLINARL 347 + G I I Q SGA+I++ P + + TI G+ I A+ LI ++ Sbjct: 394 KGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKI 447 Score = 47.8 bits (112), Expect = 2e-05 Identities = 70/272 (25%), Positives = 114/272 (41%), Gaps = 39/272 (14%) Query: 94 SRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGV 151 SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153 Query: 152 PQSVTECVKQICLVMLETLSQSP-----QGRVMTIPYQPMPASSP--VICAGGQ--DRCS 202 P+SV + K++ ++E +P G + +PAS VI GG+ + Sbjct: 154 PESV-QSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212 Query: 203 DAAGYPHATHDLEGPPLDAYSIQGQHTISPL----DLAKLNQVARQQSHFAMMHGGTGFA 258 + AG +GP Q PL D K+ Q GG Sbjct: 213 ERAGVKMVMIQ-DGP-------QNTGADKPLRITGDPYKVQQAKEMVLELIRDQGG---- 260 Query: 259 GIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANP 318 EV+ + S + ++ IP +G +IGR G I +I+ +G +I+ P Sbjct: 261 -----FREVRNEYGSRIGGNEGI-DVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KP 313 Query: 319 VEGSSGRQVT-ITGSAASISLAQYLINARLSS 349 +G++ ++ ITG A +I L S Sbjct: 314 DDGTTPERIAQITGPPDRCQHAAEIITDLLRS 345 Score = 47.0 bits (110), Expect = 3e-05 Identities = 36/165 (21%), Positives = 77/165 (46%), Gaps = 7/165 (4%) Query: 18 LLMHGKEVGSIIGKKGESVKRIREESGAR-INISEG---NCPERIITLTGPTNAIFKAFA 73 +++ + G +IGK GE++K+++E +G + + I +G ++ + +TG + +A Sbjct: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249 Query: 74 MIIDKLEEDINSSMTNSTAASR--PPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQV 131 M+++ + + + SR + + +P G +IG+ G IK+I+ G ++ Sbjct: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309 Query: 132 QVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQG 176 Q D + ER I G P + I ++ + +P G Sbjct: 310 QFKPDD-GTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGG 353 Score = 38.1 bits (87), Expect = 0.012 Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 5/66 (7%) Query: 24 EVGSIIGKKGESVKRIREESGARINISEGNCPE-----RIITLTGPTNAIFKAFAMIIDK 78 + G IIGK GE++K I ++SGARI + P ++ T+ G I A +I +K Sbjct: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446 Query: 79 LEEDIN 84 + +N Sbjct: 447 IGGPVN 452 >gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] Length = 492 Score = 75.1 bits (183), Expect = 9e-14 Identities = 52/178 (29%), Positives = 94/178 (52%), Gaps = 25/178 (14%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CPERIITLTGPTNAIFK 70 +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+ Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94 Query: 71 AFAMIIDKLEEDINSSMTNSTAAS--RPPVTL--------RLVVPATQCGSLIGKGGCKI 120 + I +K+ E I +MT + +P T+ +L+VP + G +IGKGG + Sbjct: 95 VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153 Query: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQ 175 K + E +GA VQ++ P N ER +T++G P+ V + V I ++ + + PQ Sbjct: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAI----VQKVQEDPQ 205 Score = 64.7 bits (156), Expect = 1e-10 Identities = 32/77 (41%), Positives = 53/77 (68%), Gaps = 3/77 (3%) Query: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVE---GSSGRQVTITGSAASISLA 339 E+ +P NL+G I+G+ G + E ++++GA+I+I+ E G+ R+VTITGS A+ A Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469 Query: 340 QYLINARLSSEKGMGCS 356 QYLI+ R++ E+G+ S Sbjct: 470 QYLISQRVTYEQGVRAS 486 Score = 54.7 bits (130), Expect = 1e-07 Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 17/118 (14%) Query: 17 RLLMHGKEVGSIIGKKGESVKRIREESGARINISEG----NCPERIITLTGPTNAIFKAF 72 +L++ G IIGK G +VK + E+SGA + +S+ N ER++T++G + KA Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193 Query: 73 AMIIDKLEEDINSS-------------MTNSTAASRPPVTLRLVVPATQCGSLIGKGG 117 + I+ K++ED SS + NS P + V+PA S G Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251 Score = 47.4 bits (111), Expect = 2e-05 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Query: 92 AASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149 AA + + VP G+++GKGG + E +E TGA++Q++ G+ LP + R +TI Sbjct: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460 Query: 150 GVP 152 G P Sbjct: 461 GSP 463 Score = 38.9 bits (89), Expect = 0.007 Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 2/59 (3%) Query: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS--GRQVTITGSAASISLA 339 +L +PN+ G IIG+ GA + + + SGA ++++ EG + R VT++G + A Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192 Score = 31.2 bits (69), Expect = 1.5 Identities = 17/64 (26%), Positives = 36/64 (56%), Gaps = 3/64 (4%) Query: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVE---GSSGRQVTITGSAASISLA 339 ++ IP+ G IIG+ G I ++++ +GA IK++ + G++ R + G+A +++ Sbjct: 36 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95 Query: 340 QYLI 343 I Sbjct: 96 HSFI 99 Score = 30.8 bits (68), Expect = 1.9 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 7/69 (10%) Query: 25 VGSIIGKKGESVKRIREESGARINISE-----GNCPERIITLTGPTNAIFKAFAMIIDKL 79 VG+I+GK G+++ +E +GARI IS+ R +T+TG A A +I ++ Sbjct: 418 VGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRV 477 Query: 80 --EEDINSS 86 E+ + +S Sbjct: 478 TYEQGVRAS 486 >gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 isoform 1 [Homo sapiens] Length = 577 Score = 73.2 bits (178), Expect = 3e-13 Identities = 81/358 (22%), Positives = 143/358 (39%), Gaps = 67/358 (18%) Query: 3 AGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGNCPERII 59 AG V + +RLL+ + VG+IIGK+G +++ I +++ ++I++ E+ I Sbjct: 185 AGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAI 244 Query: 60 TLTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCK 119 ++ A MI++ + ++ + T V L+++ G LIGK G Sbjct: 245 SVHSTPEGCSSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRN 298 Query: 120 IKEIRESTGAQVQVAG--DMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGR 177 +K++ + T ++ ++ D+ + ER IT+ G ++ ++I + E Sbjct: 299 LKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE------ 352 Query: 178 VMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAK 237 +D A A S+Q H I L+LA Sbjct: 353 ------------------------NDVA---------------AMSLQ-SHLIPGLNLAA 372 Query: 238 LNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGR 297 + S SS Y + + A Q ++ IP +G IIG+ Sbjct: 373 VGLFPASSS---------AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGK 423 Query: 298 QGANINEIRQMSGAQIKIANP-VEGSSGRQVTITGSAASISLAQYLINARLSSEKGMG 354 +G +I ++ + + A IKIA P S R V ITG + AQ I +L E G Sbjct: 424 KGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFG 481 Score = 71.2 bits (173), Expect = 1e-12 Identities = 44/136 (32%), Positives = 74/136 (54%), Gaps = 12/136 (8%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPE---RIITLTGPTNAIFKAF 72 +++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ +TGP A FKA Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467 Query: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLR--LVVPATQCGSLIGKGGCKIKEIRESTGAQ 130 I KL+E+ + + V L + VPA+ G +IGKGG + E++ T A+ Sbjct: 468 GRIYGKLKEE-------NFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 520 Query: 131 VQVAGDMLPNSTERAI 146 V V D P+ ++ I Sbjct: 521 VVVPRDQTPDENDQVI 536 Score = 60.5 bits (145), Expect = 2e-09 Identities = 54/230 (23%), Positives = 99/230 (43%), Gaps = 47/230 (20%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNC-----PERIITLTGPTNAIFK 70 +++L H VG +IGK+G ++K++ +++ +I IS PER IT+ G + Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 338 Query: 71 AFAMIIDKLEEDINSSMT----------------------NSTAASRPPVTL-------- 100 A I+ K+ E + + +S+A PP ++ Sbjct: 339 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 398 Query: 101 ----------RLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150 ++ +PA G++IGK G IK++ A +++A P+S R + I G Sbjct: 399 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 458 Query: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSP--VICAGGQ 198 P++ + +I + E P+ V + +PAS+ VI GG+ Sbjct: 459 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 508 Score = 29.6 bits (65), Expect = 4.3 Identities = 16/63 (25%), Positives = 26/63 (41%) Query: 253 GGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQ 312 GG G G V + L +P +G IIG++GA I I + + ++ Sbjct: 169 GGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSK 228 Query: 313 IKI 315 I + Sbjct: 229 IDV 231 >gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 [Homo sapiens] Length = 579 Score = 72.0 bits (175), Expect = 8e-13 Identities = 42/137 (30%), Positives = 72/137 (52%), Gaps = 8/137 (5%) Query: 13 TLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPE---RIITLTGPTNAIF 69 T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ +TGP A F Sbjct: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464 Query: 70 KAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGA 129 KA I K++E+ S + + VP+ G +IGKGG + E++ + A Sbjct: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519 Query: 130 QVQVAGDMLPNSTERAI 146 +V V D P+ ++ + Sbjct: 520 EVVVPRDQTPDENDQVV 536 Score = 58.5 bits (140), Expect = 9e-09 Identities = 80/388 (20%), Positives = 157/388 (40%), Gaps = 72/388 (18%) Query: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI----SEGNCPERIITLTGP--TNA 67 L +RLL+ + VG+IIGK+G +++ I +++ ++I++ + G + I L+ P T+A Sbjct: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255 Query: 68 IFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIREST 127 K+ I+ K +DI + + L+++ G LIGK G +K+I + T Sbjct: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306 Query: 128 GAQVQVA--GDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQP 185 ++ ++ ++ + ER IT+ G ++ + ++I ++ + +S + + ++ Q Sbjct: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEI----MKKIRESYENDIASMNLQ- 361 Query: 186 MPASSPVICAGGQDRCSDAAGYPHATHDLEGPP---------LDAYSIQGQHTISP---- 232 P + +G P T GPP + + H P Sbjct: 362 -AHLIPGLNLNALGLFPPTSGMPPPT---SGPPSAMTPPYPQFEQSETETVHLFIPALSV 417 Query: 233 -LDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVK----------------------- 268 + K Q +Q S FA G + +P+ K Sbjct: 418 GAIIGKQGQHIKQLSRFA----GASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGK 473 Query: 269 ---GYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGR 325 + S + + +P+ G +IG+ G +NE++ +S A++ + Sbjct: 474 IKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDEND 533 Query: 326 QVT--ITGSAASISLAQYLINARLSSEK 351 QV ITG + +AQ I L+ K Sbjct: 534 QVVVKITGHFYACQVAQRKIQEILTQVK 561 Score = 33.5 bits (75), Expect = 0.30 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 2/102 (1%) Query: 239 NQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQ 298 +++A QQ+ G G SS G S L +P +G IIG++ Sbjct: 156 DEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGS-VSKQKPCDLPLRLLVPTQFVGAIIGKE 214 Query: 299 GANINEIRQMSGAQIKIANPVE-GSSGRQVTITGSAASISLA 339 GA I I + + ++I + G++ + +TI + S A Sbjct: 215 GATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSAA 256 >gi|238624257 insulin-like growth factor 2 mRNA binding protein 1 isoform 2 [Homo sapiens] Length = 438 Score = 71.2 bits (173), Expect = 1e-12 Identities = 44/136 (32%), Positives = 74/136 (54%), Gaps = 12/136 (8%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPE---RIITLTGPTNAIFKAF 72 +++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ +TGP A FKA Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328 Query: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLR--LVVPATQCGSLIGKGGCKIKEIRESTGAQ 130 I KL+E+ + + V L + VPA+ G +IGKGG + E++ T A+ Sbjct: 329 GRIYGKLKEE-------NFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 381 Query: 131 VQVAGDMLPNSTERAI 146 V V D P+ ++ I Sbjct: 382 VVVPRDQTPDENDQVI 397 Score = 60.5 bits (145), Expect = 2e-09 Identities = 54/230 (23%), Positives = 99/230 (43%), Gaps = 47/230 (20%) Query: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNC-----PERIITLTGPTNAIFK 70 +++L H VG +IGK+G ++K++ +++ +I IS PER IT+ G + Sbjct: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199 Query: 71 AFAMIIDKLEEDINSSMT----------------------NSTAASRPPVTL-------- 100 A I+ K+ E + + +S+A PP ++ Sbjct: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259 Query: 101 ----------RLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150 ++ +PA G++IGK G IK++ A +++A P+S R + I G Sbjct: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319 Query: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSP--VICAGGQ 198 P++ + +I + E P+ V + +PAS+ VI GG+ Sbjct: 320 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 369 Score = 47.8 bits (112), Expect = 2e-05 Identities = 63/287 (21%), Positives = 109/287 (37%), Gaps = 64/287 (22%) Query: 77 DKLEEDINSSMTNSTAASRPP------VTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQ 130 +++ + +++ N T ++R V L+++ G LIGK G +K++ + T + Sbjct: 111 EQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETK 170 Query: 131 VQVAG--DMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPA 188 + ++ D+ + ER IT+ G ++ ++I + E Sbjct: 171 ITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYE----------------- 213 Query: 189 SSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHF 248 +D A A S+Q H I L+LA + S Sbjct: 214 -------------NDVA---------------AMSLQS-HLIPGLNLAAVGLFPASSS-- 242 Query: 249 AMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQM 308 SS Y + + A Q ++ IP +G IIG++G +I ++ + Sbjct: 243 -------AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRF 295 Query: 309 SGAQIKIANP-VEGSSGRQVTITGSAASISLAQYLINARLSSEKGMG 354 + A IKIA P S R V ITG + AQ I +L E G Sbjct: 296 ASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFG 342 >gi|145312259 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 56.6 bits (135), Expect = 3e-08 Identities = 42/147 (28%), Positives = 82/147 (55%), Gaps = 21/147 (14%) Query: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI-SEGNCPERIITLTGPTNAIFKAF 72 + I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104 Query: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQV- 131 + + K + I+ +T +T PV+ +L VP G +IG+GG I+ I +++GA++ Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159 Query: 132 ---QVAGDMLPNSTERAITIAGVPQSV 155 + G +L R I I+G + V Sbjct: 160 CDKESEGTLL---LSRLIKISGTQKEV 183 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 2/80 (2%) Query: 274 LDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGS--SGRQVTITG 331 L +T + +L++P +G IIGR G I I + SGA+I EG+ R + I+G Sbjct: 119 LTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178 Query: 332 SAASISLAQYLINARLSSEK 351 + ++ A++LI ++S ++ Sbjct: 179 TQKEVAAAKHLILEKVSEDE 198 Score = 40.0 bits (92), Expect = 0.003 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Query: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYL 342 E+ +P + IIGRQGANI ++R+ +GA+I + G R + I+G + A+ Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE-RVLLISGFPVQVCKAKAA 114 Query: 343 INARLS 348 I+ L+ Sbjct: 115 IHQILT 120 Score = 40.0 bits (92), Expect = 0.003 Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGN-CPERIITLTGPTN 66 N ++ +L + + VG IIG+ GE+++ I + SGA+I SEG R+I ++G Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181 Query: 67 AIFKAFAMIIDKLEED 82 + A +I++K+ ED Sbjct: 182 EVAAAKHLILEKVSED 197 Score = 39.3 bits (90), Expect = 0.005 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Query: 91 TAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150 T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103 Query: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQ 198 P V + I ++ E S Q V P + +I GG+ Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV------PQRSVGRIIGRGGE 145 >gi|145312270 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 56.6 bits (135), Expect = 3e-08 Identities = 42/147 (28%), Positives = 82/147 (55%), Gaps = 21/147 (14%) Query: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI-SEGNCPERIITLTGPTNAIFKAF 72 + I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104 Query: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQV- 131 + + K + I+ +T +T PV+ +L VP G +IG+GG I+ I +++GA++ Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159 Query: 132 ---QVAGDMLPNSTERAITIAGVPQSV 155 + G +L R I I+G + V Sbjct: 160 CDKESEGTLL---LSRLIKISGTQKEV 183 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 2/80 (2%) Query: 274 LDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGS--SGRQVTITG 331 L +T + +L++P +G IIGR G I I + SGA+I EG+ R + I+G Sbjct: 119 LTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178 Query: 332 SAASISLAQYLINARLSSEK 351 + ++ A++LI ++S ++ Sbjct: 179 TQKEVAAAKHLILEKVSEDE 198 Score = 40.0 bits (92), Expect = 0.003 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Query: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYL 342 E+ +P + IIGRQGANI ++R+ +GA+I + G R + I+G + A+ Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE-RVLLISGFPVQVCKAKAA 114 Query: 343 INARLS 348 I+ L+ Sbjct: 115 IHQILT 120 Score = 40.0 bits (92), Expect = 0.003 Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGN-CPERIITLTGPTN 66 N ++ +L + + VG IIG+ GE+++ I + SGA+I SEG R+I ++G Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181 Query: 67 AIFKAFAMIIDKLEED 82 + A +I++K+ ED Sbjct: 182 EVAAAKHLILEKVSED 197 Score = 39.3 bits (90), Expect = 0.005 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Query: 91 TAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150 T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103 Query: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQ 198 P V + I ++ E S Q V P + +I GG+ Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV------PQRSVGRIIGRGGE 145 >gi|145312256 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 56.6 bits (135), Expect = 3e-08 Identities = 42/147 (28%), Positives = 82/147 (55%), Gaps = 21/147 (14%) Query: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI-SEGNCPERIITLTGPTNAIFKAF 72 + I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104 Query: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQV- 131 + + K + I+ +T +T PV+ +L VP G +IG+GG I+ I +++GA++ Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159 Query: 132 ---QVAGDMLPNSTERAITIAGVPQSV 155 + G +L R I I+G + V Sbjct: 160 CDKESEGTLL---LSRLIKISGTQKEV 183 Score = 44.7 bits (104), Expect = 1e-04 Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 2/80 (2%) Query: 274 LDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGS--SGRQVTITG 331 L +T + +L++P +G IIGR G I I + SGA+I EG+ R + I+G Sbjct: 119 LTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISG 178 Query: 332 SAASISLAQYLINARLSSEK 351 + ++ A++LI ++S ++ Sbjct: 179 TQKEVAAAKHLILEKVSEDE 198 Score = 40.0 bits (92), Expect = 0.003 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Query: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYL 342 E+ +P + IIGRQGANI ++R+ +GA+I + G R + I+G + A+ Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDE-RVLLISGFPVQVCKAKAA 114 Query: 343 INARLS 348 I+ L+ Sbjct: 115 IHQILT 120 Score = 40.0 bits (92), Expect = 0.003 Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGN-CPERIITLTGPTN 66 N ++ +L + + VG IIG+ GE+++ I + SGA+I SEG R+I ++G Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181 Query: 67 AIFKAFAMIIDKLEED 82 + A +I++K+ ED Sbjct: 182 EVAAAKHLILEKVSED 197 Score = 39.3 bits (90), Expect = 0.005 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Query: 91 TAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150 T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103 Query: 151 VPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQ 198 P V + I ++ E S Q V P + +I GG+ Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV------PQRSVGRIIGRGGE 145 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,386,173 Number of Sequences: 37866 Number of extensions: 610013 Number of successful extensions: 1457 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 57 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 1035 Number of HSP's gapped (non-prelim): 270 length of query: 356 length of database: 18,247,518 effective HSP length: 103 effective length of query: 253 effective length of database: 14,347,320 effective search space: 3629871960 effective search space used: 3629871960 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.