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Search of human proteins with 222144283
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222144283 hypothetical protein LOC65998 [Homo sapiens]
(678 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222144283 hypothetical protein LOC65998 [Homo sapiens] 1416 0.0
gi|39930523 hypothetical protein LOC144097 [Homo sapiens] 66 9e-11
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 53 1e-06
gi|157676340 zinc finger protein 142 [Homo sapiens] 52 1e-06
gi|30089948 protein phosphatase 1E [Homo sapiens] 52 2e-06
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 52 2e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 51 3e-06
gi|45827731 scribble isoform a [Homo sapiens] 50 5e-06
gi|116256475 zinc finger protein 827 [Homo sapiens] 49 2e-05
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 49 2e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 49 2e-05
gi|56549694 enabled homolog isoform a [Homo sapiens] 48 3e-05
gi|39930375 enabled homolog isoform b [Homo sapiens] 48 3e-05
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 47 4e-05
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 47 6e-05
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 47 6e-05
gi|55741677 SET domain containing 1A [Homo sapiens] 47 6e-05
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 47 8e-05
gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens] 47 8e-05
gi|188528652 hypothetical protein LOC745 isoform 2 [Homo sapiens] 47 8e-05
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 46 1e-04
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens] 46 1e-04
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens] 46 1e-04
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 46 1e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 45 2e-04
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 45 2e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 45 2e-04
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 45 2e-04
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 45 2e-04
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 45 2e-04
>gi|222144283 hypothetical protein LOC65998 [Homo sapiens]
Length = 678
Score = 1416 bits (3665), Expect = 0.0
Identities = 678/678 (100%), Positives = 678/678 (100%)
Query: 1 MEPGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSW 60
MEPGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSW
Sbjct: 1 MEPGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSW 60
Query: 61 GSAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPA 120
GSAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPA
Sbjct: 61 GSAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPA 120
Query: 121 RHGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAE 180
RHGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAE
Sbjct: 121 RHGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAE 180
Query: 181 GLGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRRQRRGGPVAPRARRLRLS 240
GLGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRRQRRGGPVAPRARRLRLS
Sbjct: 181 GLGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRRQRRGGPVAPRARRLRLS 240
Query: 241 ASRRAGGSRGLGARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGRALPSLHLDDI 300
ASRRAGGSRGLGARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGRALPSLHLDDI
Sbjct: 241 ASRRAGGSRGLGARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGRALPSLHLDDI 300
Query: 301 RAHVLEVHPGSLGLSGPQRSALLQAWGGQPEALSELTQSPPGDDLAPQDLTGKSRDSASA 360
RAHVLEVHPGSLGLSGPQRSALLQAWGGQPEALSELTQSPPGDDLAPQDLTGKSRDSASA
Sbjct: 301 RAHVLEVHPGSLGLSGPQRSALLQAWGGQPEALSELTQSPPGDDLAPQDLTGKSRDSASA 360
Query: 361 AGAPSSQDLSPPDVKEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSPRGRAHRRHPQE 420
AGAPSSQDLSPPDVKEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSPRGRAHRRHPQE
Sbjct: 361 AGAPSSQDLSPPDVKEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSPRGRAHRRHPQE 420
Query: 421 RWRLEYLMELDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREW 480
RWRLEYLMELDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREW
Sbjct: 421 RWRLEYLMELDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREW 480
Query: 481 SEKAAHLLALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLE 540
SEKAAHLLALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLE
Sbjct: 481 SEKAAHLLALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLE 540
Query: 541 RPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGL 600
RPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGL
Sbjct: 541 RPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGL 600
Query: 601 VCMVCGGALATLKVSTIKRHILQVHPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPA 660
VCMVCGGALATLKVSTIKRHILQVHPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPA
Sbjct: 601 VCMVCGGALATLKVSTIKRHILQVHPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPA 660
Query: 661 PAPRDGGADLKSGAVCRA 678
PAPRDGGADLKSGAVCRA
Sbjct: 661 PAPRDGGADLKSGAVCRA 678
>gi|39930523 hypothetical protein LOC144097 [Homo sapiens]
Length = 381
Score = 66.2 bits (160), Expect = 9e-11
Identities = 48/142 (33%), Positives = 64/142 (45%), Gaps = 20/142 (14%)
Query: 544 EEEEDEEDGQEPGGLALPPP----------PPPPPPPPPRSRE--QRRNYQPRWRGEYLM 591
EE EDEE+ + P P PPP P P + + Q W E+L+
Sbjct: 20 EEGEDEEEAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLV 79
Query: 592 DYD--GSRRGLVCMVCGGALATLKVSTIKRHILQVHPFSMDFTPEERQTILEAYEE--AA 647
GS R L CMVCG + T + HIL+ HP ++D +P E+ ILEA+ E A
Sbjct: 80 GSSPGGSGRAL-CMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVAL 138
Query: 648 LRCYGHEGFGPPAPAPRDGGAD 669
L+ E P+P D G D
Sbjct: 139 LQDVRAE---QPSPPNSDSGQD 157
Score = 50.8 bits (120), Expect = 4e-06
Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 19/114 (16%)
Query: 271 ECLMDYDPRGN-RLVCMACGRALPSLHLDDIRAHVLEVHPGSLGLSGPQRSALLQAWGGQ 329
E L+ P G+ R +CM CG + + D R+H+LE HP +L LS ++S +L+AW
Sbjct: 76 EFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEG 135
Query: 330 PEALSELTQSPPGDDLAPQDLTGKSRDSASAAGAPSSQDLSP-PDVKEEAGWVP 382
L ++ P S + S QD P PD +A +P
Sbjct: 136 VALLQDVRAEQP-----------------SPPNSDSGQDAHPDPDANPDAARMP 172
Score = 50.4 bits (119), Expect = 5e-06
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 109 WRLEYLMDFNPARHGM-VCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSW 167
W E+L+ +P G +CMVCG+ + T + HI ++HP++L SP EK I +W
Sbjct: 73 WEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAW 132
Query: 168 DAHLGL 173
+ L
Sbjct: 133 SEGVAL 138
Score = 49.3 bits (116), Expect = 1e-05
Identities = 60/224 (26%), Positives = 84/224 (37%), Gaps = 21/224 (9%)
Query: 375 KEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSP--RGRAHRRHPQER--WRLEYLM-E 429
+EEA V P P E L + E+ P SP G P+++ W E+L+
Sbjct: 25 EEEAMVVAVIPRP---EPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGS 81
Query: 430 LDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLA 489
GG +C VCG + + T HI +HP + L ++ I WSE A L
Sbjct: 82 SPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQD 141
Query: 490 LGPPRPESPQGPIPPGTAAASD-EGGGDEEEEPEE-----EEEEWGDVPLSPG----APL 539
+ +P P G A D + D P E + E+ +P PL
Sbjct: 142 VRAEQPSPPNS--DSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPL 199
Query: 540 ERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQP 583
E PA E ++P G PP P R R +N P
Sbjct: 200 ELPA-VPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDP 242
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 52.8 bits (125), Expect = 1e-06
Identities = 70/313 (22%), Positives = 113/313 (36%), Gaps = 60/313 (19%)
Query: 297 LDDIRAHV-LEVHPGSLGLSGPQRSAL-LQAWGGQPEALSELTQSPPGDDLAPQDLTGKS 354
L+D++ + + H G L Q+ A QA Q + + Q PP Q +
Sbjct: 1730 LEDLKQQIQTQHHVGQTQLQILQQQAQQYQATQPQLQPQKQQQQPPPPQQQQQQQASKLL 1789
Query: 355 RDSASAAGAPSSQDLSPPDVKEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSPRGRAH 414
+ S + Q + +EA + E+P ++E + EGEG + G + +
Sbjct: 1790 KQEQSNIVSADCQIMKDVPSYKEAEDISEKP-EKPKQEFISEGEGLKEGKDTKKQKSLEP 1848
Query: 415 RRHPQ---------------ERWRLEYLMELDGGRRG---------------LVCGVCGG 444
P E + E +++ + R+ L CG CG
Sbjct: 1849 SIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENTDKLECGTCGK 1908
Query: 445 ALAS-LKMSTIERHIRRRHPGSTRLGGPVQAL--IAREWSEKAAHLLALGPPRPESPQGP 501
++ L + + + H+ + P AL AR++ E L + P PE+P P
Sbjct: 1909 LFSNVLILKSHQEHVHGQF-------FPYAALEKFARQYREAYDKLYPISPSSPETPPPP 1961
Query: 502 IPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALP 561
PP + P+ +P + PL+ P P P
Sbjct: 1962 PPPPPLPPAP---------PQPSSMGPVKIPNTVSTPLQAPPPTP--------PPPPPPP 2004
Query: 562 PPPPPPPPPPPRS 574
PPPPPPPPPPP S
Sbjct: 2005 PPPPPPPPPPPPS 2017
Score = 38.9 bits (89), Expect = 0.016
Identities = 14/17 (82%), Positives = 14/17 (82%)
Query: 558 LALPPPPPPPPPPPPRS 574
L PPPPPPPPPPPP S
Sbjct: 3114 LQTPPPPPPPPPPPPSS 3130
Score = 35.8 bits (81), Expect = 0.13
Identities = 14/28 (50%), Positives = 16/28 (57%)
Query: 561 PPPPPPPPPPPPRSREQRRNYQPRWRGE 588
PPPPPPPPPPP S ++ Q E
Sbjct: 3118 PPPPPPPPPPPSSSLSGQQTEQQNKESE 3145
Score = 35.4 bits (80), Expect = 0.17
Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
Query: 535 PGAPLERPAEEEEDEEDGQEPGGLALP--PPPPPPPPPPPRSREQRRNYQP 583
P A LE+ A + + D P + P PPPPPPPPP P + Q + P
Sbjct: 1929 PYAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGP 1979
Score = 33.1 bits (74), Expect = 0.86
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 5/96 (5%)
Query: 110 RLEYLMDFNPARHGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDA 169
+L+ ++ R +C +C S T + +K+H+ HP S E + + S
Sbjct: 1366 KLQIHSQYHAIRAATMCNLCQRSFRTFQ--ALKKHLEAGHP---ELSEAELQQLYASLPV 1420
Query: 170 HLGLGACGEAEGLGVQGAEEEEEEEEEEEEEGAGVP 205
+ L A E G E+E E E E + EG P
Sbjct: 1421 NGELWAESETMSQDDHGLEQEMEREYEVDHEGKASP 1456
>gi|157676340 zinc finger protein 142 [Homo sapiens]
Length = 1687
Score = 52.4 bits (124), Expect = 1e-06
Identities = 71/252 (28%), Positives = 96/252 (38%), Gaps = 47/252 (18%)
Query: 333 LSELTQSPPGDDLAPQDLTGKSRDSASAAGAPSSQDLSPPDVKEEAGWVPERPGPAEEEE 392
+SE + +PP + AP + G + + A AP PP + E+ R E+ E
Sbjct: 762 VSEPSTNPPSLEEAPNNWVGTFKTTPPAETAPL-----PPLPESESLLKALRRQDKEQAE 816
Query: 393 ELE-EGEGERAGVPGRSPRGRAHR-RHPQERWRLEYLMEL------DGGRRGLVCGVCGG 444
L EG + + G GRA R H R E + L G R L+C CG
Sbjct: 817 ALVLEGRVQMVVIQGE---GRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECG- 872
Query: 445 ALASLKMST-IERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESP--QGP 501
AS K + H+ ++ P R G PRP+SP P
Sbjct: 873 --ASFKQQRGLSTHLLKKCPVLLRKNK--------------------GLPRPDSPIPLQP 910
Query: 502 IPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALP 561
+ PGT A+ D G +E E + L APLE P E EE EE G +P
Sbjct: 911 VLPGTQASEDTESGKPPPASQEAE-----LLLPKDAPLELPREPEETEEPLATVSGSPVP 965
Query: 562 PPPPPPPPPPPR 573
P P P+
Sbjct: 966 PAGNSLPTEAPK 977
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/106 (37%), Positives = 48/106 (45%), Gaps = 32/106 (30%)
Query: 493 PRPESPQGPIP--------------PG----TAAASDEGGGDEEEEPEEEEEEWGDVPLS 534
P PES P P PG T AA++EG D+E++PE EEE
Sbjct: 41 PEPESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEG--DQEQDPEPEEE-------- 90
Query: 535 PGAPLERPAEEEEDEEDGQEPGGLALPPPPP--PPPPPPPRSREQR 578
A +E EEE PG A+PPPPP PP PP PR +R
Sbjct: 91 --AAVEGEEEEEGAATAAAAPGHSAVPPPPPQLPPLPPLPRPLSER 134
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 51.6 bits (122), Expect = 2e-06
Identities = 39/117 (33%), Positives = 43/117 (36%), Gaps = 9/117 (7%)
Query: 461 RHPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESPQGPIPPGTAAASDEGG----GD 516
R PG GGP A + + LGPP P P GP PPG G GD
Sbjct: 216 RFPGPAGPGGPPPPFPAGQTPPRPP----LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGD 271
Query: 517 EEEEPEE-EEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPP 572
P + +G PL P P P G P PPPP P PP PP
Sbjct: 272 RPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPP 328
Score = 31.2 bits (69), Expect = 3.3
Identities = 37/160 (23%), Positives = 56/160 (35%), Gaps = 13/160 (8%)
Query: 431 DGGRRGLVCGVCGGALASLKMSTI--ERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLL 488
+G +G G +S K+ + +R + ++P T P ++ ++
Sbjct: 120 NGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVT----PCNKQFLSQFEMQSRKTT 175
Query: 489 ALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
G E GP + AA +GG P GD P P P
Sbjct: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPG--GDRFPGPAGPGGPPPPFPAG 233
Query: 549 EEDGQEPGGLALPPPPPPPPP-----PPPRSREQRRNYQP 583
+ + P G PP PP PPP PPP + R +P
Sbjct: 234 QTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP 273
Score = 30.0 bits (66), Expect = 7.3
Identities = 26/84 (30%), Positives = 26/84 (30%), Gaps = 15/84 (17%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PPRP P GP P T A G P P AP PA
Sbjct: 324 PPRPPGPLGP--PLTLAPPPHLPGPPPGAP-------------PPAPHVNPAFFPPPTNS 368
Query: 552 GQEPGGLALPPPPPPPPPPPPRSR 575
G PPP P PPP R
Sbjct: 369 GMPTSDSRGPPPTDPYGRPPPYDR 392
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 51.2 bits (121), Expect = 3e-06
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 8/93 (8%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
GPP P PQGP P G + S +P+ + G+ P P P +P + +
Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPR---SPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQ 185
Query: 551 DGQEPGGLALPPPPPPPPPPPPRSREQRRNYQP 583
G++P G PPPP P PPP+ + R + P
Sbjct: 186 GGKKPQG---PPPPGKPQGPPPQGDKSRSSQSP 215
Score = 48.9 bits (115), Expect = 2e-05
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 8/93 (8%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
GPP P PQGP P G + S +P+ + G+ P P P +P + +
Sbjct: 70 GPPPPGKPQGPPPQGDKSRSPR---SPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQ 124
Query: 551 DGQEPGGLALPPPPPPPPPPPPRSREQRRNYQP 583
G P G PPPP P PPP+ + R P
Sbjct: 125 GGNRPQG---PPPPGKPQGPPPQGDKSRSPRSP 154
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
GPP P PQGP P G + S + +P+ + G+ P P P +P + +
Sbjct: 192 GPPPPGKPQGPPPQGDKSRSSQ---SPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQ 246
Query: 551 DGQEPGGLALPPPPPPPPPPP 571
G +P G PPPP P PP
Sbjct: 247 GGNKPQG---PPPPGKPQGPP 264
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 9/81 (11%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP P PQGP P G + + P + GD SP +P +P + +
Sbjct: 51 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ----GDKSRSPRSPPGKP--QGPPPQG 104
Query: 552 GQEPGGLALPPPPPPPPPPPP 572
G +P G PPPPP P PP
Sbjct: 105 GNQPQG---PPPPPGKPQGPP 122
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/122 (27%), Positives = 46/122 (37%), Gaps = 30/122 (24%)
Query: 481 SEKAAHLLALGPPRPESPQG-------PIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPL 533
S++ + L G P+ SPQG P PPG GG++ + P
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP---------- 73
Query: 534 SPGAPLERPAEEEEDEEDGQEPGGLALPPPP-------PPPPP-----PPPRSREQRRNY 581
PG P P + ++ PG PPP PPPPP PPP+ + +
Sbjct: 74 -PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP 132
Query: 582 QP 583
P
Sbjct: 133 PP 134
Score = 40.0 bits (92), Expect = 0.007
Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 8/92 (8%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP P PQGP P G + + P + ++ PG P P +
Sbjct: 173 PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ------G 226
Query: 552 GQEPGGLALPPPPPPPPPPPPRSREQRRNYQP 583
G +P G PPPP P PPP+ + + P
Sbjct: 227 GNQPQGP--PPPPGKPQGPPPQGGNKPQGPPP 256
Score = 38.1 bits (87), Expect = 0.027
Identities = 30/98 (30%), Positives = 36/98 (36%), Gaps = 21/98 (21%)
Query: 491 GPPRP--ESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
GPP PQGP PPG GG + + PG P + P ++E +
Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS----------PPGKP-QGPPQQEGN 290
Query: 549 EEDGQEP--GGLALPPPPPP------PPPPPPRSREQR 578
G P GG P PP PP PP R R
Sbjct: 291 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 50.4 bits (119), Expect = 5e-06
Identities = 98/411 (23%), Positives = 136/411 (33%), Gaps = 79/411 (19%)
Query: 19 GPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALG----------SWGSAPLPSS 68
GP A GR L P A G ++ GA G S P P S
Sbjct: 1250 GPEATEAAGRGLQPLKLDYRALAAVPSAGSVQRVPSGAAGGKMAESPCSPSGQQPPSPPS 1309
Query: 69 RARGPASSGRKYS-----------DHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDF 117
PA+ + Y + A+ PG + P + R ++ LE +
Sbjct: 1310 PDELPANVKQAYRAFAAVPTSHPPEDAPAQPPTPGPAASPEQLSFRERQKYFELEVRVPQ 1369
Query: 118 NPARHGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACG 177
V +V L ++ ++ ++QK L +E +A L L
Sbjct: 1370 AEGPPKRVSLVGADDLRKMQEEEARK-LQQKRAQML------REAAEAGAEARLAL---- 1418
Query: 178 EAEGLGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRRQRRGGPVAPRARRL 237
+ E LG EEE+E+E+ A + P P GG R RL
Sbjct: 1419 DGETLG-------EEEQEDEQPPWASPSPTSRQSPASPPPLGGGAPVRTAKAERRHQERL 1471
Query: 238 RLSASRRAGGSRGLGARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGRALPSLHL 297
R+ + R L L E W A + SL
Sbjct: 1472 RVQSPEPPAPERALSPAELRALEAEKRALWRAAR--------------------MKSLEQ 1511
Query: 298 DDIRAH-VLEVHPGSLGLSGPQRSALLQAWGGQPEALSELTQSP-PGDDLAPQ------- 348
D +RA VL G GP L +A P T SP P +DL PQ
Sbjct: 1512 DALRAQMVLSRSQEGRGTRGP-LERLAEAPSPAP------TPSPTPVEDLGPQTSTSPGR 1564
Query: 349 -DLTGKSRDSASAAGAPSSQ---DLSPPDVKEEAGWVPERPGPAEEEEELE 395
L+GK D + A PSS+ D+ PD EE + P P +EE+ E
Sbjct: 1565 LPLSGKKFDYRAFAALPSSRPVYDIQSPDFAEELRSLEPSPSPGPQEEDGE 1615
Score = 35.8 bits (81), Expect = 0.13
Identities = 66/291 (22%), Positives = 99/291 (34%), Gaps = 62/291 (21%)
Query: 318 QRSALLQAWGGQPEA---LSELTQSPPGDDLAPQDLTGKSRDSASAAGAPSSQDLSPPDV 374
Q+ +L + W P + + + ++P GD+ A + K A PS + +
Sbjct: 429 QQGSLSETWSDAPPSRVSVIQFLEAPIGDEDAEEAAAEKRGLQRRATPHPSELKVMKRSI 488
Query: 375 K----EEAGWVPER--PGPAEEEEELEEGEG-ERAGVPGRSPRGRAHRRHPQERWRLEYL 427
+ E P+ P PAEEE+ L G P S A P
Sbjct: 489 EGRRSEACPCQPDSGSPLPAEEEKRLSAESGLSEDSRPSASTVSEAEPEGPSA------- 541
Query: 428 MELDGG--RRGLVCGVCGGALASLKMSTI-----------ERHIRRRHPGST-RLGGPVQ 473
E GG + G A + T+ +R I P + L G Q
Sbjct: 542 -EAQGGSQQEATTAGGEEDAEEDYQEPTVHFAEDALLPGDDREIEEGQPEAPWTLPGGRQ 600
Query: 474 ALIAREWSEKAAHLLALGPPRPESP-----------QGPIPPG----------TAAASDE 512
LI ++ H P+PE+ +GP+ PG A E
Sbjct: 601 RLIRKDTPHYKKHFKISKLPQPEAVVALLQGMQPDGEGPVAPGGWHNGPHAPWAPRAQKE 660
Query: 513 GGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPP 563
+EE P+EEEEE + E AEEEE + ++ G + P
Sbjct: 661 EEEEEEGSPQEEEEEEEE---------ENRAEEEEASTEEEDKEGAVVSAP 702
>gi|116256475 zinc finger protein 827 [Homo sapiens]
Length = 1077
Score = 48.5 bits (114), Expect = 2e-05
Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 10/93 (10%)
Query: 533 LSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPRWR---GEY 589
L P PL P E++ E+ P PPPPPPPPPPPP+S E P+ R
Sbjct: 309 LLPEDPLPPPPSEKKPEKVTPPP-----PPPPPPPPPPPPQSLELLLLPVPKGRVSKPSN 363
Query: 590 LMDYDGSRRGLVCMVCGGALATLKVSTIKRHIL 622
+ S + C +CG L + S KRH++
Sbjct: 364 SASEEESGKPFQCPICG--LVIKRKSYWKRHMV 394
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/75 (40%), Positives = 34/75 (45%), Gaps = 30/75 (40%)
Query: 516 DEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQE------------------PGG 557
+EEEE +EEEEE E A +E+DEED E PG
Sbjct: 23 EEEEEGDEEEEE------------EVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGC 70
Query: 558 LALPPPPPPPPPPPP 572
PPPPPPPPP PP
Sbjct: 71 HLFPPPPPPPPPLPP 85
Score = 31.2 bits (69), Expect = 3.3
Identities = 15/24 (62%), Positives = 17/24 (70%)
Query: 178 EAEGLGVQGAEEEEEEEEEEEEEG 201
E EG+ + EEEEE EEE EEEG
Sbjct: 483 EKEGVQWEAKEEEEEYEEEGEEEG 506
Score = 30.0 bits (66), Expect = 7.3
Identities = 16/32 (50%), Positives = 18/32 (56%)
Query: 172 GLGACGEAEGLGVQGAEEEEEEEEEEEEEGAG 203
G +C E GVQ +EEEEE EEE E G
Sbjct: 475 GKWSCPHCEKEGVQWEAKEEEEEYEEEGEEEG 506
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 8/90 (8%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
GPP P PQGP P G + S +P+ + G+ P P P +P + +
Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPR---SPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQ 145
Query: 551 DGQEPGGLALPPPPPPPPPPPPRSREQRRN 580
G +P G PPPP P PPP+ + R+
Sbjct: 146 GGNKPQG---PPPPGKPQGPPPQGDNKSRS 172
Score = 48.1 bits (113), Expect = 3e-05
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 7/90 (7%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
GPP P PQGP P G + +P+ + G+ P P P +P + +
Sbjct: 276 GPPPPGKPQGPPPQG--GSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQ 331
Query: 551 DGQEPGGLALPPPPPPPPPPPPRSREQRRN 580
G +P G PPPP P PPP+ + R+
Sbjct: 332 GGNKPQG---PPPPGKPQGPPPQGGSKSRS 358
Score = 47.4 bits (111), Expect = 4e-05
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 7/90 (7%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
GPP P PQGP P G + +P+ + G+ P P P +P + +
Sbjct: 214 GPPPPGKPQGPPPQGD--NKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQ 269
Query: 551 DGQEPGGLALPPPPPPPPPPPPRSREQRRN 580
G +P G PPPP P PPP+ + R+
Sbjct: 270 GGNKPQG---PPPPGKPQGPPPQGGSKSRS 296
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/128 (26%), Positives = 48/128 (37%), Gaps = 35/128 (27%)
Query: 491 GPPRPESPQGP------------IPPGTAAASDEGGGDEEE-------EPEEEEEEWGDV 531
GPP P PQGP PPG GG++ + +P+ + G+
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 211
Query: 532 PLSP---GAPLERPAEEEEDEEDGQEPGGLALPPPP--------PPPPP-----PPPRSR 575
P P G P P + + + + P G PPP PPPPP PPP+
Sbjct: 212 PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 271
Query: 576 EQRRNYQP 583
+ + P
Sbjct: 272 NKPQGPPP 279
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 18/109 (16%)
Query: 491 GPPRPES-PQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSP---GAPLERPAEEE 546
GPP P PQGP P G +G +P+ + G+ P P G P P + +
Sbjct: 49 GPPSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 106
Query: 547 EDEEDGQEPGGLALPPPP-------PPPPP-----PPPRSREQRRNYQP 583
+ PG PPP PPPPP PPP+ + + P
Sbjct: 107 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 155
Score = 40.0 bits (92), Expect = 0.007
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 9/100 (9%)
Query: 491 GPPRP--ESPQGPIPP-GTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEE 547
GPP PQGP PP G GG++ + P + G P G R +
Sbjct: 244 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP--QGGSKSRSSRSPP 301
Query: 548 DEEDGQEPGGLALPPPPPPPP----PPPPRSREQRRNYQP 583
+ G P G P PPPPP PPP+ + + P
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 341
Score = 38.1 bits (87), Expect = 0.027
Identities = 30/105 (28%), Positives = 40/105 (38%), Gaps = 23/105 (21%)
Query: 481 SEKAAHLLALGPPRPESPQG-------PIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPL 533
S++ + L G P+ PQG P PPG GG++ + P P
Sbjct: 24 SQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP----------PP 73
Query: 534 SPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQR 578
PG P P + G +P G P P PPP +SR R
Sbjct: 74 PPGKPQGPPPQ------GGNKPQGPPPPGKPQGPPPQGDKSRSPR 112
Score = 37.7 bits (86), Expect = 0.035
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 10/84 (11%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
GPP P PQGP P G + +P+ ++ G+ P P P ++ +
Sbjct: 338 GPPPPGKPQGPPPQG--GSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395
Query: 551 DGQEPGGLALPPPPP----PPPPP 570
GQ G PP PP P PP
Sbjct: 396 AGQPQG----PPRPPQGGRPSRPP 415
Score = 36.6 bits (83), Expect = 0.078
Identities = 30/98 (30%), Positives = 37/98 (37%), Gaps = 14/98 (14%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLS----PGAPLERPAEEEE 547
PP P PQGP P G + G +P+ + G S PG P P +E
Sbjct: 319 PPPPGKPQGPPPQG---GNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGN 375
Query: 548 DEEDGQEP-GGLALPPPPPP------PPPPPPRSREQR 578
+ + P GG P PP PP PP R R
Sbjct: 376 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 413
Score = 32.0 bits (71), Expect = 1.9
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 4/63 (6%)
Query: 521 PEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRN 580
P+ + G+ P P +P +P + + G +P G PPPP P PPP+ + +
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKP--QGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNKPQG 91
Query: 581 YQP 583
P
Sbjct: 92 PPP 94
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 47.8 bits (112), Expect = 3e-05
Identities = 55/188 (29%), Positives = 72/188 (38%), Gaps = 34/188 (18%)
Query: 390 EEEELEEGEGERAGVPGRSPRGRAHRRHPQERW----RLEYLMELDGGRRGLVCGVCGGA 445
E E LE+ + ER R R R R QER RLE LD R+
Sbjct: 182 ERERLEQEQLERE----RQERERQERLERQERLERQERLERQERLDRERQ---------- 227
Query: 446 LASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESPQGPIPPG 505
+ +ER R R + + L EW + A P E+P +
Sbjct: 228 -ERQERERLERLERERQERERQEQLEREQL---EWERERRISSAAAPASVETPLNSVLGD 283
Query: 506 TAAASDEGGGDEEEEPEEEEEEWGDV--PLSPGAPLERPAEEEEDEEDGQEPGGLALPPP 563
++A+ E G +P E + G V PL+P P P G +ALPPP
Sbjct: 284 SSAS--EPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPP--------GPAQASVALPPP 333
Query: 564 PPPPPPPP 571
P PPPPPP
Sbjct: 334 PGPPPPPP 341
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/196 (28%), Positives = 68/196 (34%), Gaps = 29/196 (14%)
Query: 383 ERPGPAEEEEELEEGEGERAGVPGRSPRGRAHR--RHPQERWRLEYLM--ELDGGRRGLV 438
ER E +E LE E R R R R R QER R E L +L+ R +
Sbjct: 205 ERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRI 264
Query: 439 CGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESP 498
A ++++ PG P + S++ L L PP P
Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETP-----SQQGIVLGPLAPPPPP-- 317
Query: 499 QGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGL 558
P+PPG A AS P G P P PL Q P
Sbjct: 318 --PLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPN-----------QVP--- 361
Query: 559 ALPPPPPPPPPPPPRS 574
PPPPPPP PP P S
Sbjct: 362 --PPPPPPPAPPLPAS 375
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 47.8 bits (112), Expect = 3e-05
Identities = 55/188 (29%), Positives = 72/188 (38%), Gaps = 34/188 (18%)
Query: 390 EEEELEEGEGERAGVPGRSPRGRAHRRHPQERW----RLEYLMELDGGRRGLVCGVCGGA 445
E E LE+ + ER R R R R QER RLE LD R+
Sbjct: 182 ERERLEQEQLERE----RQERERQERLERQERLERQERLERQERLDRERQ---------- 227
Query: 446 LASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESPQGPIPPG 505
+ +ER R R + + L EW + A P E+P +
Sbjct: 228 -ERQERERLERLERERQERERQEQLEREQL---EWERERRISSAAAPASVETPLNSVLGD 283
Query: 506 TAAASDEGGGDEEEEPEEEEEEWGDV--PLSPGAPLERPAEEEEDEEDGQEPGGLALPPP 563
++A+ E G +P E + G V PL+P P P G +ALPPP
Sbjct: 284 SSAS--EPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPP--------GPAQASVALPPP 333
Query: 564 PPPPPPPP 571
P PPPPPP
Sbjct: 334 PGPPPPPP 341
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/196 (28%), Positives = 68/196 (34%), Gaps = 29/196 (14%)
Query: 383 ERPGPAEEEEELEEGEGERAGVPGRSPRGRAHR--RHPQERWRLEYLM--ELDGGRRGLV 438
ER E +E LE E R R R R R QER R E L +L+ R +
Sbjct: 205 ERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRI 264
Query: 439 CGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESP 498
A ++++ PG P + S++ L L PP P
Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETP-----SQQGIVLGPLAPPPPP-- 317
Query: 499 QGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGL 558
P+PPG A AS P G P P PL Q P
Sbjct: 318 --PLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPN-----------QVP--- 361
Query: 559 ALPPPPPPPPPPPPRS 574
PPPPPPP PP P S
Sbjct: 362 --PPPPPPPAPPLPAS 375
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/84 (35%), Positives = 34/84 (40%), Gaps = 26/84 (30%)
Query: 488 LALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEE 547
L + PP P +P+GP PPG GG P P PGA
Sbjct: 347 LGIAPP-PPTPRGPPPPGR-------GGPPPPPPPATGRSGPLPPPPPGA---------- 388
Query: 548 DEEDGQEPGGLALPPPPPPPPPPP 571
GG +PPPPPPPPPPP
Sbjct: 389 --------GGPPMPPPPPPPPPPP 404
Score = 30.0 bits (66), Expect = 7.3
Identities = 12/19 (63%), Positives = 13/19 (68%)
Query: 555 PGGLALPPPPPPPPPPPPR 573
P G+A PPP P PPPP R
Sbjct: 346 PLGIAPPPPTPRGPPPPGR 364
Score = 29.6 bits (65), Expect = 9.6
Identities = 12/19 (63%), Positives = 12/19 (63%), Gaps = 4/19 (21%)
Query: 561 PPPP----PPPPPPPPRSR 575
PPPP PPPPPPP R
Sbjct: 359 PPPPGRGGPPPPPPPATGR 377
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 47.0 bits (110), Expect = 6e-05
Identities = 32/89 (35%), Positives = 36/89 (40%), Gaps = 15/89 (16%)
Query: 492 PPRPESPQGPIPPGTAAASDEG--GGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDE 549
PP P P P+P G +S GG P GD + P PL E
Sbjct: 602 PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLS---GDATIPPPPPLP---EGVGIP 655
Query: 550 EDGQEPGGLALPPPPP-------PPPPPP 571
PGG A+PPPPP PPPPPP
Sbjct: 656 SPSSLPGGTAIPPPPPLPGSARIPPPPPP 684
Score = 42.4 bits (98), Expect = 0.001
Identities = 19/41 (46%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 532 PLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPP 572
P+ P PL P + PG PPPPPPPPPPPP
Sbjct: 572 PVPPAPPL--PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP 610
Score = 42.0 bits (97), Expect = 0.002
Identities = 29/91 (31%), Positives = 32/91 (35%), Gaps = 16/91 (17%)
Query: 489 ALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
A+ PP P S IPP G P G + P PL P
Sbjct: 629 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP-------GGTAIPPPPPL--PGSARIP 679
Query: 549 EEDGQEPGGLALPPPPPP-------PPPPPP 572
PG +PPPPPP PPPPPP
Sbjct: 680 PPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP 710
Score = 37.0 bits (84), Expect = 0.060
Identities = 27/83 (32%), Positives = 29/83 (34%), Gaps = 24/83 (28%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP P IPP E G P +P PG P P
Sbjct: 681 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPP---------LPGGPGIPPPPPF-------- 723
Query: 552 GQEPGGLALPPPPP----PPPPP 570
PGG +PPPPP PPPPP
Sbjct: 724 ---PGGPGIPPPPPGMGMPPPPP 743
Score = 33.1 bits (74), Expect = 0.86
Identities = 11/12 (91%), Positives = 11/12 (91%)
Query: 561 PPPPPPPPPPPP 572
PPPPPPPPPP P
Sbjct: 602 PPPPPPPPPPLP 613
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 47.0 bits (110), Expect = 6e-05
Identities = 32/89 (35%), Positives = 36/89 (40%), Gaps = 15/89 (16%)
Query: 492 PPRPESPQGPIPPGTAAASDEG--GGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDE 549
PP P P P+P G +S GG P GD + P PL E
Sbjct: 611 PPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLS---GDATIPPPPPLP---EGVGIP 664
Query: 550 EDGQEPGGLALPPPPP-------PPPPPP 571
PGG A+PPPPP PPPPPP
Sbjct: 665 SPSSLPGGTAIPPPPPLPGSARIPPPPPP 693
Score = 42.4 bits (98), Expect = 0.001
Identities = 19/41 (46%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 532 PLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPP 572
P+ P PL P + PG PPPPPPPPPPPP
Sbjct: 581 PVPPAPPL--PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP 619
Score = 42.0 bits (97), Expect = 0.002
Identities = 29/91 (31%), Positives = 32/91 (35%), Gaps = 16/91 (17%)
Query: 489 ALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
A+ PP P S IPP G P G + P PL P
Sbjct: 638 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP-------GGTAIPPPPPL--PGSARIP 688
Query: 549 EEDGQEPGGLALPPPPPP-------PPPPPP 572
PG +PPPPPP PPPPPP
Sbjct: 689 PPPPPLPGSAGIPPPPPPLPGEAGMPPPPPP 719
Score = 37.0 bits (84), Expect = 0.060
Identities = 27/83 (32%), Positives = 29/83 (34%), Gaps = 24/83 (28%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP P IPP E G P +P PG P P
Sbjct: 690 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPP---------LPGGPGIPPPPPF-------- 732
Query: 552 GQEPGGLALPPPPP----PPPPP 570
PGG +PPPPP PPPPP
Sbjct: 733 ---PGGPGIPPPPPGMGMPPPPP 752
Score = 33.1 bits (74), Expect = 0.86
Identities = 11/12 (91%), Positives = 11/12 (91%)
Query: 561 PPPPPPPPPPPP 572
PPPPPPPPPP P
Sbjct: 611 PPPPPPPPPPLP 622
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 47.0 bits (110), Expect = 6e-05
Identities = 31/85 (36%), Positives = 36/85 (42%), Gaps = 14/85 (16%)
Query: 501 PIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSP---GAPLERPAEEEEDEEDGQEPGG 557
P P +EG + EEE EEEEEE D S GA R
Sbjct: 1349 PKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRR------ 1402
Query: 558 LALPPPPPPPPPPPPRSREQRRNYQ 582
PPPPPPPPPPR+ E R ++
Sbjct: 1403 -----PPPPPPPPPPRAYEPRSEFE 1422
Score = 43.9 bits (102), Expect = 5e-04
Identities = 67/290 (23%), Positives = 95/290 (32%), Gaps = 64/290 (22%)
Query: 315 SGPQRSALLQAWGGQPEALSELTQSPPG--DDLAPQDLTGKSRDSASAAGAPSSQDLSPP 372
S P R A + G P A + + PP L P+ SR + P+S+ +PP
Sbjct: 381 SYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEP----SRPTDQDYRPPASE--APP 434
Query: 373 DVKEEAGWVPERPGPAEEEEELEEG----EGERAGVPGRSPRGRA--HRRHPQERWRLEY 426
E G GP+ E EE+ R+G P + +H R+E
Sbjct: 435 PEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEM 494
Query: 427 LMELDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAH 486
L++ K S + S+ + G E + H
Sbjct: 495 LLKEQRS----------------KFSFLASDTEEEEENSSMVLGARDT--GSEVPSGSGH 536
Query: 487 LLALGPPRPES-----PQGPIPPGTAAASDEGGGDEEEEP--------EEEEEEWGDVPL 533
PP P + P G PG S + G + P +++ G P
Sbjct: 537 GPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPP 596
Query: 534 SPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQP 583
+P P Q+P PPPPPPPPPPPP Y P
Sbjct: 597 APTPP--------------QQP-----PPPPPPPPPPPPYLASLPLGYPP 627
Score = 38.9 bits (89), Expect = 0.016
Identities = 29/83 (34%), Positives = 31/83 (37%), Gaps = 25/83 (30%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP P PQ P PP P +PL G P +PA D
Sbjct: 595 PPAPTPPQQPPPP-------------PPPPPPPPPYLASLPL--GYPPHQPAYLLPPRPD 639
Query: 552 GQEPGGLALPPPP--PPPPPPPP 572
G PPPP PPPPPPPP
Sbjct: 640 G--------PPPPEYPPPPPPPP 654
Score = 36.2 bits (82), Expect = 0.10
Identities = 29/106 (27%), Positives = 37/106 (34%), Gaps = 28/106 (26%)
Query: 506 TAAASDEGGGDEEEEPEEEEEEWG----------DVPLSPGAPLERPAEEE--------- 546
++++S + E EEEEE +VP+ AP+E P E
Sbjct: 1049 SSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPL 1108
Query: 547 -EDEEDGQEPGG--------LALPPPPPPPPPPPPRSREQRRNYQP 583
E E P G L PP PP PP P R R P
Sbjct: 1109 PEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSP 1154
Score = 35.8 bits (81), Expect = 0.13
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 9/79 (11%)
Query: 517 EEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSRE 576
+ +EP E E + P P E ++ E E++ EPG P PP+ E
Sbjct: 896 KRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGR---------PGTKPPKRDE 946
Query: 577 QRRNYQPRWRGEYLMDYDG 595
+R Q + R + +D +G
Sbjct: 947 ERGKTQGKHRKSFALDSEG 965
Score = 34.7 bits (78), Expect = 0.30
Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 15/97 (15%)
Query: 493 PRPE----SPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
P PE SP P+P A+ + G EE P + P P AP RP E
Sbjct: 1095 PVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRP-PEPPAGPPAPAPRPDERPSS 1153
Query: 549 EEDGQEP----------GGLALPPPPPPPPPPPPRSR 575
P + + P P PPP PP+++
Sbjct: 1154 PIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAK 1190
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 46.6 bits (109), Expect = 8e-05
Identities = 35/123 (28%), Positives = 44/123 (35%), Gaps = 18/123 (14%)
Query: 481 SEKAAHLLALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPL------S 534
S + A + L P + P P GGDE+ P +PL S
Sbjct: 49 SRREAEEMKLEPLQEREPA----PEENLTWSSSGGDEKVLPS--------IPLRCHSSSS 96
Query: 535 PGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPRWRGEYLMDYD 594
P P +P + + GL+ PPPPP PPPPP WRG
Sbjct: 97 PVCPRRKPRPRPQPRARSRSQPGLSAPPPPPARPPPPPPPPPPPAPRPRAWRGSRRRSRP 156
Query: 595 GSR 597
GSR
Sbjct: 157 GSR 159
>gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens]
Length = 1111
Score = 46.6 bits (109), Expect = 8e-05
Identities = 34/99 (34%), Positives = 39/99 (39%), Gaps = 19/99 (19%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSP------GAP--LERP 542
GPP P+ P PGT S G E P++ E ++P G P LE P
Sbjct: 110 GPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHP 169
Query: 543 AEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNY 581
P LP PPPPPPPPP QR Y
Sbjct: 170 P-----------PPPAHLPGPPPPPPPPPHYPVLQRDLY 197
>gi|188528652 hypothetical protein LOC745 isoform 2 [Homo sapiens]
Length = 1151
Score = 46.6 bits (109), Expect = 8e-05
Identities = 34/99 (34%), Positives = 39/99 (39%), Gaps = 19/99 (19%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSP------GAP--LERP 542
GPP P+ P PGT S G E P++ E ++P G P LE P
Sbjct: 119 GPPIKAEPKAPYAPGTLPDSPPDSGSEAYSPQQVNEPHLLRTITPETLCHVGVPSRLEHP 178
Query: 543 AEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNY 581
P LP PPPPPPPPP QR Y
Sbjct: 179 P-----------PPPAHLPGPPPPPPPPPHYPVLQRDLY 206
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 46.2 bits (108), Expect = 1e-04
Identities = 73/332 (21%), Positives = 103/332 (31%), Gaps = 62/332 (18%)
Query: 309 PGSLGLSGPQRSALLQAWGGQPEALSELTQSPPGDDLAPQDLTGKSRDSASAAGAPSSQD 368
PG L L GP+ + L L + + L + T + A P +++
Sbjct: 868 PGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNRE 927
Query: 369 LSP-----PDVKEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSPRGRAHRRHPQERWR 423
P P V P P LE G+ G+ ++ A +E
Sbjct: 928 KVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKV 987
Query: 424 LEY-----------------LMELDGGRRGLVCGVCGGALASLKMST-----IERHIRRR 461
LE L + G + LV G + K+S R+ R
Sbjct: 988 LENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERP 1047
Query: 462 -HPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESPQGPIPPGTAAASDEGGGDEEEE 520
G R GP + W +G P PE+ P +A S GG+
Sbjct: 1048 PETGPWRAPGPWEKT-PESWGPAPT----IGEPAPETSLERAPAPSAVVSSRNGGETAPG 1102
Query: 521 P--------------EEEEEEWGDVPLSPGAP-LERPAEEEEDEEDGQEPGG-------- 557
P E E G P +PGA L+ + G PGG
Sbjct: 1103 PLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDA 1162
Query: 558 ------LALPPPPPPPPPPPPRSREQRRNYQP 583
P PPPPP PPPP ++ +R P
Sbjct: 1163 KAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAP 1194
Score = 43.1 bits (100), Expect = 8e-04
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 5/56 (8%)
Query: 167 WDAHLGLGACGEAEGLGVQG-----AEEEEEEEEEEEEEGAGVPACPPKGPGKAPA 217
W+ A GEA G G G E+E+E+EEE+EE A A P+GPG+A A
Sbjct: 1282 WEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARA 1337
Score = 37.4 bits (85), Expect = 0.046
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 516 DEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDG---QEPGGLALPPPPPPPPPPPP 572
+++ E D+P++P P P E + Q PG PPP PPPPPPPP
Sbjct: 734 EDDSSLRAERGSLADLPMAP--PASAPPEFLDPLMGAAAPQYPG--RGPPPAPPPPPPPP 789
Query: 573 RS 574
R+
Sbjct: 790 RA 791
Score = 36.6 bits (83), Expect = 0.078
Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 12/95 (12%)
Query: 492 PPRPESPQGPI----PPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSP-------GAPLE 540
PP P +P P PP A+ G +P + E + P SP GA E
Sbjct: 786 PPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYET-ETPFSPEGAFPGGGAAEE 844
Query: 541 RPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSR 575
+ +PG PP P P P P PR +
Sbjct: 845 EGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREK 879
Score = 35.0 bits (79), Expect = 0.23
Identities = 40/156 (25%), Positives = 57/156 (36%), Gaps = 36/156 (23%)
Query: 469 GGPVQALIAREWSEKAAHLLALGPPRPESPQGP--IP------------------PGTAA 508
G P + L +W L G P P++PQ P +P P ++
Sbjct: 575 GSPPEPLFPNDWDP-----LDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSS 629
Query: 509 ASD---------EGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLA 559
AS EG G E + E G+ +P +E EEEE G++ L
Sbjct: 630 ASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPW--VEEEEEEEEGSSPGEDSSSLG 687
Query: 560 LPPPPPPPPPPPPRSREQRRNYQPRWRGEYLMDYDG 595
P P P P SRE + P RG+ + + G
Sbjct: 688 GGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGG 723
Score = 32.7 bits (73), Expect = 1.1
Identities = 11/12 (91%), Positives = 11/12 (91%)
Query: 562 PPPPPPPPPPPR 573
PP PPPPPPPPR
Sbjct: 445 PPRPPPPPPPPR 456
Score = 32.0 bits (71), Expect = 1.9
Identities = 70/278 (25%), Positives = 91/278 (32%), Gaps = 73/278 (26%)
Query: 330 PEALSE-LTQSPPG--DDLAPQDLTGKSRDSASAAGAPSSQDLSPPDVKEEAGWVPERPG 386
PEA L +PP ++AP+ G + DS + S D PP PER G
Sbjct: 1183 PEAQPRRLEPAPPRARPEVAPEGEPG-APDSRAGGDTALSGDGDPPK--------PERKG 1233
Query: 387 PAEEEEELEEG--EGERAGVPGRSPR--------------GRAHRRHPQERWRLEYLMEL 430
P L+ G +G + R R G RR P E
Sbjct: 1234 PEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWE---------- 1283
Query: 431 DGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLAL 490
G G G GGA A PG G + E E AA A
Sbjct: 1284 -GADAGAAGGEAGGAGA---------------PGPAEEDGEDEDEDEEEDEEAAAPGAAA 1327
Query: 491 GPPRP-ESPQGPIPPGTAAASDEG------------GGDEEEEPEEEEEE-----WGDVP 532
GP P + P+P ++A + G DE E+ E E + GDV
Sbjct: 1328 GPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVT 1387
Query: 533 LSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPP 570
+ E P E + + + PP PP PP P
Sbjct: 1388 VYL-FDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHP 1424
Score = 30.8 bits (68), Expect = 4.3
Identities = 10/11 (90%), Positives = 10/11 (90%)
Query: 561 PPPPPPPPPPP 571
PP PPPPPPPP
Sbjct: 445 PPRPPPPPPPP 455
>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
Length = 755
Score = 45.8 bits (107), Expect = 1e-04
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 506 TAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPP 565
TAA+ EGG E E PE E + P A + E DGQ+ A PP P
Sbjct: 11 TAASPGEGGAGEAE-PEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP 69
Query: 566 PPPPPP 571
PPPPPP
Sbjct: 70 PPPPPP 75
Score = 38.5 bits (88), Expect = 0.021
Identities = 32/91 (35%), Positives = 35/91 (38%), Gaps = 20/91 (21%)
Query: 495 PESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQE 554
P P P PPG A S E G PE E EE V ++ A
Sbjct: 66 PPLPPPPPPPGELARSPEAVG-----PELEAEEKLSVRVAESAA-------------AAP 107
Query: 555 PGGLALPPPPPPPP--PPPPRSREQRRNYQP 583
GG LPP P PP PP P RE+ QP
Sbjct: 108 QGGPELPPSPASPPEQPPAPEEREEPPLPQP 138
>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
Length = 560
Score = 45.8 bits (107), Expect = 1e-04
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 506 TAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPP 565
TAA+ EGG E E PE E + P A + E DGQ+ A PP P
Sbjct: 11 TAASPGEGGAGEAE-PEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLP 69
Query: 566 PPPPPP 571
PPPPPP
Sbjct: 70 PPPPPP 75
Score = 38.5 bits (88), Expect = 0.021
Identities = 32/91 (35%), Positives = 35/91 (38%), Gaps = 20/91 (21%)
Query: 495 PESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQE 554
P P P PPG A S E G PE E EE V ++ A
Sbjct: 66 PPLPPPPPPPGELARSPEAVG-----PELEAEEKLSVRVAESAA-------------AAP 107
Query: 555 PGGLALPPPPPPPP--PPPPRSREQRRNYQP 583
GG LPP P PP PP P RE+ QP
Sbjct: 108 QGGPELPPSPASPPEQPPAPEEREEPPLPQP 138
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 45.8 bits (107), Expect = 1e-04
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 1/83 (1%)
Query: 492 PPRPESPQGPIPP-GTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
PP P P+GP P G + S + + P ++E P PG P P ++
Sbjct: 156 PPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQ 215
Query: 551 DGQEPGGLALPPPPPPPPPPPPR 573
P G PPPPP PPR
Sbjct: 216 PQAPPAGKPQGPPPPPQGGRPPR 238
Score = 44.3 bits (103), Expect = 4e-04
Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 19/109 (17%)
Query: 492 PPRPESPQGPIPPG---TAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
PP P PQGP P G + G E P+ + G P PG P ERP + +
Sbjct: 51 PPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPP-HPGKP-ERPPPQGGN 108
Query: 549 EEDGQEP------------GGLALPPPPPP--PPPPPPRSREQRRNYQP 583
+ G P G + PPPPP P PPP+ Q + P
Sbjct: 109 QSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPP 157
Score = 40.4 bits (93), Expect = 0.005
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 7/92 (7%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP P P+ P P G +G +PE + G+ S +P +P + +++
Sbjct: 135 PPPPGKPERPPPQG--GNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKP--QGPPQQE 190
Query: 552 GQEPGGLALPPPPPPPPPPPPRSREQRRNYQP 583
G +P G PPPP P PPP ++ P
Sbjct: 191 GNKPQG---PPPPGKPQGPPPAGGNPQQPQAP 219
Score = 38.9 bits (89), Expect = 0.016
Identities = 35/130 (26%), Positives = 45/130 (34%), Gaps = 43/130 (33%)
Query: 481 SEKAAHLLALGPPRPESPQG-------PIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPL 533
S++ + L G P PQG P PPG GG++ + P P
Sbjct: 24 SQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGP----------PP 73
Query: 534 SPGAPLERPAEE-EEDEEDGQEPGGLALPPP---------PPPP---------------- 567
PG P RP + + + PG PPP PPPP
Sbjct: 74 PPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHR 133
Query: 568 PPPPPRSREQ 577
PPPPP E+
Sbjct: 134 PPPPPGKPER 143
Score = 37.7 bits (86), Expect = 0.035
Identities = 28/96 (29%), Positives = 37/96 (38%), Gaps = 13/96 (13%)
Query: 492 PPRPESPQGPIPPG--TAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDE 549
PP P P+ P P G + + G E P + + P PG P ERP + ++
Sbjct: 93 PPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKP-ERPPPQGGNQ 151
Query: 550 EDGQEPGGLALPPPPP--PPPPPPPRSREQRRNYQP 583
G PPP P P PPP + R P
Sbjct: 152 SQG--------PPPHPGKPEGPPPQEGNKSRSARSP 179
Score = 33.5 bits (75), Expect = 0.66
Identities = 26/95 (27%), Positives = 31/95 (32%), Gaps = 4/95 (4%)
Query: 3 PGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSWGS 62
PG R GG G + R PP G + S P G + G S G
Sbjct: 96 PGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGP 155
Query: 63 APLPSSRARGPASSGRKYSDHCEARASRPGKSRIP 97
P P P G K + S PGK + P
Sbjct: 156 PPHPGKPEGPPPQEGNK----SRSARSPPGKPQGP 186
Score = 30.8 bits (68), Expect = 4.3
Identities = 20/77 (25%), Positives = 25/77 (32%)
Query: 3 PGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSWGS 62
PG GG GP + PP G + S P G + G S G+
Sbjct: 54 PGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGT 113
Query: 63 APLPSSRARGPASSGRK 79
P P R P G +
Sbjct: 114 PPPPGKPERPPPQGGNQ 130
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/82 (35%), Positives = 34/82 (41%), Gaps = 17/82 (20%)
Query: 491 GPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEE 550
GPP + + P+ A+ G EE LSPG R E+
Sbjct: 194 GPPVKRAAEPPVVQPVPPAALSGPSGEEG-------------LSPGGKRRRGCNSEQTGL 240
Query: 551 DGQEPGGLALPPPPPPPPPPPP 572
P GL LPPPP PPPPPPP
Sbjct: 241 ----PPGLPLPPPPLPPPPPPP 258
Score = 32.7 bits (73), Expect = 1.1
Identities = 25/85 (29%), Positives = 31/85 (36%), Gaps = 11/85 (12%)
Query: 493 PRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDG 552
P P S +PP +AA S +G +P P A R EE
Sbjct: 839 PGPPSGATALPPTSAAPSAQGS----PQPSASSSSQFSTSGGPWARERRAGEEPV----- 889
Query: 553 QEPGGLALPPPPPPPPPPPPRSREQ 577
PG + PPPP PP RS +
Sbjct: 890 --PGPMTPTQPPPPLSLPPARSESE 912
Score = 32.3 bits (72), Expect = 1.5
Identities = 16/37 (43%), Positives = 18/37 (48%), Gaps = 11/37 (29%)
Query: 549 EEDGQEPGGLALPPP-----------PPPPPPPPPRS 574
EE+ + P L PPP PPPPPPP P S
Sbjct: 766 EEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPAS 802
Score = 31.6 bits (70), Expect = 2.5
Identities = 25/96 (26%), Positives = 31/96 (32%), Gaps = 19/96 (19%)
Query: 491 GPPRPESPQGPIPPGTAA--ASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
GPPRP P P G AS G ++ P +P P +
Sbjct: 510 GPPRPAPPPLPHREGFLGPPASRFSVGTQDSH----------TPPTPPTPTTSSSNSNSG 559
Query: 549 EEDGQEPGGLALPPPP-------PPPPPPPPRSREQ 577
G ++ PPPP P P PP P Q
Sbjct: 560 SHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQ 595
Score = 31.2 bits (69), Expect = 3.3
Identities = 49/190 (25%), Positives = 72/190 (37%), Gaps = 32/190 (16%)
Query: 356 DSASAAGAPSSQDLSPPDVKEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSPRGRAHR 415
D+A A + + + L P KEEAG V G + ++ + E R R+ + R
Sbjct: 940 DTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRR---HRRACKDSVGR 996
Query: 416 RHPQERWRLEYLMELDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQAL 475
R + R + + + + RR L +L + + E I+ R LGG
Sbjct: 997 RPREGRAKAKAKVPKEKSRR---------VLGNLDLQSEE--IQGREKSRPDLGG----- 1040
Query: 476 IAREWSEKAAHLLALGPPRPESPQG-PIPPGTAAASDEGGGDEEEEPEEEEEEWGDV--- 531
+ KA A PP +P P PP +AS G EE P D+
Sbjct: 1041 -----ASKAKPPTAPAPPSAPAPSAQPTPP---SASVPGKKAREEAPGPPGVSRADMLKL 1092
Query: 532 -PLSPGAPLE 540
LS G P E
Sbjct: 1093 RSLSEGPPKE 1102
Score = 30.0 bits (66), Expect = 7.3
Identities = 13/22 (59%), Positives = 14/22 (63%), Gaps = 4/22 (18%)
Query: 555 PGGLALPPPPPPP----PPPPP 572
P G + PPPPP P PPPPP
Sbjct: 462 PPGPSSPPPPPCPRLLRPPPPP 483
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 45.4 bits (106), Expect = 2e-04
Identities = 27/70 (38%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 509 ASDEGGGDEEEEPEEEEEEWGDVPLS---PGAPLERPAEEEEDEEDGQEPGGLAL---PP 562
A D G E+E+ EE ++ G PL PG L + P G + PP
Sbjct: 483 ADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPP 542
Query: 563 PPPPPPPPPP 572
PPPPPPPPPP
Sbjct: 543 PPPPPPPPPP 552
Score = 31.2 bits (69), Expect = 3.3
Identities = 25/91 (27%), Positives = 33/91 (36%), Gaps = 30/91 (32%)
Query: 501 PIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLAL 560
P+ T D+ D+ E E+E+E ++ PL +P PG L
Sbjct: 469 PLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPP-----------PGVGLL 517
Query: 561 PPPP-------------------PPPPPPPP 572
P PP PPPPPPPP
Sbjct: 518 PTPPRPPGPQAPTSPNGRPMQGGPPPPPPPP 548
Score = 30.8 bits (68), Expect = 4.3
Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 19/49 (38%)
Query: 534 SPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPP----PPPRSREQR 578
+PG P P+E PPPP PPPP PPP S + R
Sbjct: 4 APGTPPPPPSES---------------PPPPSPPPPSTPSPPPCSPDAR 37
Score = 29.6 bits (65), Expect = 9.6
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 186 GAEEEEEEEEEEEE---------EGAGVPACPPKGPGKAPAGGGCRRQRRGGPVAP 232
GAE+E+E EE +++ G G+ PP+ PG R +GGP P
Sbjct: 489 GAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPPP 544
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/114 (32%), Positives = 49/114 (42%), Gaps = 29/114 (25%)
Query: 493 PRPESPQGPIPPGTAAASDEGGGDEEEEPEEE------EEEWGDVPLSPGAPLER----- 541
P PE + P PP +E +EE PEEE EEE +VP P P E
Sbjct: 10791 PVPERAESP-PPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVP-PPAVPEEPKKIIP 10848
Query: 542 -------------PAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQ 582
P +E E E+ ++P L P PPPPPP PP+ + + +Q
Sbjct: 10849 EKKVPVIKKPEAPPPKEPEPEKVIEKP---KLKPRPPPPPPAPPKEDVKEKIFQ 10899
Score = 35.4 bits (80), Expect = 0.17
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 13/93 (13%)
Query: 541 RPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGL 600
+PAEE ED+ + + P P P P P S ++ R + Y+ +
Sbjct: 32295 QPAEEYEDDTERRSP----TPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMK--- 32347
Query: 601 VCMVCGGALATLKVSTIKRHILQVHPFSMDFTP 633
AL T K S K +L PF++D P
Sbjct: 32348 ------AALKTQKTSERKYEVLSQQPFTLDHAP 32374
Score = 31.6 bits (70), Expect = 2.5
Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 8/99 (8%)
Query: 482 EKAAHLLALGPPR-PESPQGPIPPGTAAASDEGGGDEEEE--PEEEEEEWGDVPLSPGAP 538
EK L A+ + PE PQ P GG + + PE + E +V L +
Sbjct: 10895 EKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLK--SV 10952
Query: 539 LERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQ 577
L + EEEE + EP L P P PPPP+ E+
Sbjct: 10953 LRKRPEEEEPKV---EPKKLEKVKKPAVPEPPPPKPVEE 10988
Score = 30.0 bits (66), Expect = 7.3
Identities = 26/101 (25%), Positives = 35/101 (34%), Gaps = 24/101 (23%)
Query: 478 REWSEKAAHLLALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGA 537
RE+ H + P P P+P EEP VP P A
Sbjct: 9774 REYERYEEHEEYITEPEKPIPVKPVP---------------EEP---------VPTKPKA 9809
Query: 538 PLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQR 578
P + ++ EE P L PPPP P P + E++
Sbjct: 9810 PPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEK 9850
Score = 30.0 bits (66), Expect = 7.3
Identities = 24/81 (29%), Positives = 30/81 (37%), Gaps = 28/81 (34%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP+PESP PP + EEPEE LE P E +E +
Sbjct: 10655 PPKPESP----PP-----------EVFEEPEE-------------VALEEPPAEVVEEPE 10686
Query: 552 GQEPGGLALPPPPPPPPPPPP 572
P + +PP P P P
Sbjct: 10687 PAAPPQVTVPPKKPVPEKKAP 10707
Score = 29.6 bits (65), Expect = 9.6
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 2/73 (2%)
Query: 502 IPPGTAAASDEGGGDEEEE--PEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLA 559
+P +E EEEE PEEEE + + P P EE EE+ P
Sbjct: 10114 VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEV 10173
Query: 560 LPPPPPPPPPPPP 572
LP P P P P
Sbjct: 10174 LPEVKPKVPVPAP 10186
Score = 29.6 bits (65), Expect = 9.6
Identities = 23/89 (25%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP+ P+ +P A + E P+E E VP+ P E P + +
Sbjct: 10500 PPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPE-KKVPVPPPKKPEVPPTKVPEVPK 10558
Query: 552 GQEPGGL---ALPPPPPPPPPPPPRSREQ 577
P A+PP P PPP P + ++
Sbjct: 10559 AAVPEKKVPEAIPPKPESPPPEVPEAPKE 10587
Score = 29.6 bits (65), Expect = 9.6
Identities = 21/79 (26%), Positives = 29/79 (36%), Gaps = 15/79 (18%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP+PESP +P E P+E E P P P + E ++
Sbjct: 10571 PPKPESPPPEVP---------------EAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKE 10615
Query: 552 GQEPGGLALPPPPPPPPPP 570
+ +PPP P PP
Sbjct: 10616 VVPEKKVPVPPPKKPEVPP 10634
Score = 29.6 bits (65), Expect = 9.6
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 13/68 (19%)
Query: 517 EEEEPEEEEEEWGDV--PLSPGAPLERPAEEEE------DEEDGQEPGGL-----ALPPP 563
EEEEP+ E ++ V P P P +P EE E E EP + A+P P
Sbjct: 10958 EEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLP 11017
Query: 564 PPPPPPPP 571
P P P P
Sbjct: 11018 APEPKPKP 11025
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/231 (27%), Positives = 90/231 (38%), Gaps = 28/231 (12%)
Query: 341 PGDDLAPQDLTGKSRDSASAAGAPSSQDLSPPDVKEEAGWVPERPGPAEEEEELEEGEGE 400
P D +P L +R+ A A+ APS SP V +RPGP + + + E
Sbjct: 1117 PLDPSSPLALALAARERALASQAPSR---SPTPVHSPDA---DRPGPLFVDVQARDPERG 1170
Query: 401 RAGVPGRSPRGRAH-----RRHPQERWRLEYLMELDGGRRGLVCGVCGGALASLKMSTIE 455
P SPR A RR ++ R E D ++ ++ V +L I
Sbjct: 1171 SLASPAFSPRSPAWIPVPARREAEKVPREERKSPED--KKSMILSVLDTSLQR-PAGLIV 1227
Query: 456 RHIRRRHPGSTRLGGPVQALIAR-EWSEKAAHLLALGPPRPESPQGPIPPGTAAASDEGG 514
H +RLGG + E + A+ P P SP+ P GT A + G
Sbjct: 1228 VHATSNGQEPSRLGGAEEERPGTPELAPAPMQSAAVAEPLP-SPRAQPPGGTPADAGPGQ 1286
Query: 515 GDEEEEPEEEEEEWGDVPLSPGAPLERPAE-EEEDEEDGQEPGGLALPPPP 564
G EEEPE + + P PA+ DEE +E + L PPP
Sbjct: 1287 GSSEEEPE--------LVFAVNLP---PAQLSSSDEETREELARIGLVPPP 1326
Score = 34.7 bits (78), Expect = 0.30
Identities = 31/134 (23%), Positives = 48/134 (35%), Gaps = 30/134 (22%)
Query: 467 RLGGPVQALIAREWSEKAAHLLALGPPRPESPQGP----IPPGTAAASDEGGGDEEEEPE 522
RL GP R A+ + G +P + GP +P + D + + +
Sbjct: 357 RLAGPSGLASPRPLQRSASDINLKGEAQPAASPGPSLRSLPHQLLLQRLQEEKDRDRDAD 416
Query: 523 EEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPP---------------- 566
+E G PL A + + + G PGG+ P PPP
Sbjct: 417 QESNISG--------PLAGRAGQSKISDPGPGPGGVGGAPLPPPGAPRSCIRIRARFPAP 468
Query: 567 --PPPPPPRSREQR 578
PP PPPR +++
Sbjct: 469 PAPPAPPPRGPKRK 482
Score = 30.0 bits (66), Expect = 7.3
Identities = 10/16 (62%), Positives = 11/16 (68%)
Query: 557 GLALPPPPPPPPPPPP 572
G +PPPP PPPPP
Sbjct: 826 GRGIPPPPQTAPPPPP 841
>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
preproprotein [Homo sapiens]
Length = 198
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 19/110 (17%)
Query: 491 GPPRPESPQGPIPPGTAAAS------------DEGGGDEEEEPEEEEEEWGDVPLSPGAP 538
GPP P PQGP P G + S +GG + P+ + G P PG P
Sbjct: 70 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPP--PGKP 127
Query: 539 LERPAEEEEDEEDGQEPGGLALPPPP-----PPPPPPPPRSREQRRNYQP 583
PA+ + + P G PP P PPPP Q+ P
Sbjct: 128 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 177
Score = 38.1 bits (87), Expect = 0.027
Identities = 22/81 (27%), Positives = 31/81 (38%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP P PQGP P G + + P + ++ PG P P + + +
Sbjct: 51 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGP 110
Query: 552 GQEPGGLALPPPPPPPPPPPP 572
+ G PPPP P PP
Sbjct: 111 PPQGGNKPQGPPPPGKPQGPP 131
Score = 37.4 bits (85), Expect = 0.046
Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 19/97 (19%)
Query: 491 GPPRP--ESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
GPP PQGP PPG GG + + PG P P +E +
Sbjct: 109 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP----------PGKPQGPPQQEGNN 158
Query: 549 EEDGQEP-GGLALPPPPPP------PPPPPPRSREQR 578
+ P GG P PP PP PP R R
Sbjct: 159 PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 195
Score = 36.2 bits (82), Expect = 0.10
Identities = 32/119 (26%), Positives = 46/119 (38%), Gaps = 15/119 (12%)
Query: 481 SEKAAHLLALGPPRPESPQG-------PIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPL 533
S++ + L G P+ SPQG P PPG GG++ + P + G P
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
Query: 534 -----SPGAPLERPAEEEEDEEDGQEP---GGLALPPPPPPPPPPPPRSREQRRNYQPR 584
SP +P +P Q P GG PPPP P P ++ ++ R
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 142
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/93 (32%), Positives = 38/93 (40%), Gaps = 9/93 (9%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSP----GAPLERPAEEEE 547
PPRP P+GP P G +G +PE + G+ P P G P P +E
Sbjct: 198 PPRPGKPEGPPPQG--GNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGN 255
Query: 548 DEEDGQEPGGLALPPPPPPPPP---PPPRSREQ 577
+ PG PPPP P PPP + Q
Sbjct: 256 KPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQ 288
Score = 42.4 bits (98), Expect = 0.001
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
Query: 492 PPRPESPQGPIPPG---TAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
PPRP P+GP P G + G E P+ + G P PG P E P + +
Sbjct: 135 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP-HPGKP-EGPPPQGGN 192
Query: 549 EEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPR 584
+ G PP P P PPP+ Q + PR
Sbjct: 193 QSQGP-------PPRPGKPEGPPPQGGNQSQGPPPR 221
Score = 39.7 bits (91), Expect = 0.009
Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 14/97 (14%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PPRP P+GP P G +G +PE + + G+ S G P RP + E
Sbjct: 72 PPRPGKPEGPPPQG--GNQSQGPPPRPGKPEGQPPQGGNQ--SQGPP-PRPGKPE----- 121
Query: 552 GQEP-GGLALPPPPP---PPPPPPPRSREQRRNYQPR 584
G P GG PPP P PPP+ Q + PR
Sbjct: 122 GPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR 158
Score = 39.7 bits (91), Expect = 0.009
Identities = 29/94 (30%), Positives = 38/94 (40%), Gaps = 9/94 (9%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEED 551
PP P P+GP P G +G +PE + G+ S G P E +
Sbjct: 177 PPHPGKPEGPPPQG--GNQSQGPPPRPGKPEGPPPQGGNQ--SQGPPPRPGKPEGPPSQG 232
Query: 552 GQEPGGLALPPPPP--PPPPPPPRSREQRRNYQP 583
G +P G PPP P P PPP + +R P
Sbjct: 233 GNKPQG---PPPHPGKPQGPPPQEGNKPQRPPPP 263
Score = 39.3 bits (90), Expect = 0.012
Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 8/90 (8%)
Query: 492 PPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSP---GAPLERPAEEEED 548
PPRP P+GP P +G +P+ + G+ P P G P P
Sbjct: 219 PPRPGKPEGP--PSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNP 276
Query: 549 EEDGQEPGGLALPPPPPPP---PPPPPRSR 575
++ P G PPPPP P PP+ +
Sbjct: 277 QQPLPPPAGKPQGPPPPPQGGRPHRPPQGQ 306
Score = 38.5 bits (88), Expect = 0.021
Identities = 32/106 (30%), Positives = 41/106 (38%), Gaps = 21/106 (19%)
Query: 492 PPRPESPQGPIPPG---TAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEED 548
PPRP P+GP P G + G E P+ + G P PG P E P + +
Sbjct: 156 PPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPP-RPGKP-EGPPPQGGN 213
Query: 549 EEDGQEP-----------GGLALPPPPPPP-----PPPPPRSREQR 578
+ G P GG PPP P PPP ++ QR
Sbjct: 214 QSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQR 259
Score = 36.6 bits (83), Expect = 0.078
Identities = 29/114 (25%), Positives = 40/114 (35%), Gaps = 10/114 (8%)
Query: 481 SEKAAHLLALGPPRPESPQG-------PIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPL 533
S++ + + G P PQG P PPG GG++ + P + P
Sbjct: 24 SQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPP 83
Query: 534 SPGAPLERPAEEEEDEEDGQEPGGLALPPPPP---PPPPPPPRSREQRRNYQPR 584
G + P E GG PPP P PPP+ Q + PR
Sbjct: 84 QGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR 137
Score = 32.3 bits (72), Expect = 1.5
Identities = 27/95 (28%), Positives = 32/95 (33%), Gaps = 4/95 (4%)
Query: 3 PGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSWGS 62
PG GG GP + PP G + S P G + Q G S G
Sbjct: 54 PGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGP 113
Query: 63 APLPSSRARGPASSGRKYSDHCEARASRPGKSRIP 97
P P + GP G S + RPGK P
Sbjct: 114 PPRP-GKPEGPPPQGGNQS---QGPPPRPGKPEGP 144
Score = 30.4 bits (67), Expect = 5.6
Identities = 26/95 (27%), Positives = 31/95 (32%), Gaps = 4/95 (4%)
Query: 3 PGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSWGS 62
PG GG GP + PP G + S P G + G S G
Sbjct: 75 PGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 134
Query: 63 APLPSSRARGPASSGRKYSDHCEARASRPGKSRIP 97
P P + GP G S + RPGK P
Sbjct: 135 PPRP-GKPEGPPPQGGNQS---QGPPPRPGKPEGP 165
Score = 30.4 bits (67), Expect = 5.6
Identities = 26/95 (27%), Positives = 31/95 (32%), Gaps = 4/95 (4%)
Query: 3 PGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSWGS 62
PG GG GP + PP G + S P G + G S G
Sbjct: 138 PGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGP 197
Query: 63 APLPSSRARGPASSGRKYSDHCEARASRPGKSRIP 97
P P + GP G S + RPGK P
Sbjct: 198 PPRP-GKPEGPPPQGGNQS---QGPPPRPGKPEGP 228
Score = 29.6 bits (65), Expect = 9.6
Identities = 26/95 (27%), Positives = 31/95 (32%), Gaps = 4/95 (4%)
Query: 3 PGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSWGS 62
PG GG GP + PP G + S P G + G S G
Sbjct: 117 PGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 176
Query: 63 APLPSSRARGPASSGRKYSDHCEARASRPGKSRIP 97
P P + GP G S + RPGK P
Sbjct: 177 PPHP-GKPEGPPPQGGNQS---QGPPPRPGKPEGP 207
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.135 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,993,719
Number of Sequences: 37866
Number of extensions: 2950239
Number of successful extensions: 60545
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 821
Number of HSP's successfully gapped in prelim test: 1216
Number of HSP's that attempted gapping in prelim test: 27916
Number of HSP's gapped (non-prelim): 21449
length of query: 678
length of database: 18,247,518
effective HSP length: 109
effective length of query: 569
effective length of database: 14,120,124
effective search space: 8034350556
effective search space used: 8034350556
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.