Search of human proteins with 222144247

Search of human proteins with 222144247

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo
sapiens]
         (597 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo sapiens]    1221   0.0  
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]    1219   0.0  
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]      63   9e-10
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H...    40   0.005
gi|223555933 dynein, axonemal, heavy polypeptide 14 isoform 2 [H...    40   0.005
gi|24497531 Ellis van Creveld syndrome protein [Homo sapiens]          37   0.052
gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]               36   0.088
gi|224586817 golgi apparatus protein 1 isoform 3 [Homo sapiens]        35   0.15 
gi|224586815 golgi apparatus protein 1 isoform 2 [Homo sapiens]        35   0.15 
gi|54633312 golgi apparatus protein 1 isoform 1 [Homo sapiens]         35   0.15 
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    34   0.44 
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    34   0.44 
gi|145046269 rotatin [Homo sapiens]                                    33   0.97 
gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 ...    32   1.7  
gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ...    32   1.7  
gi|221219015 olfactory receptor, family 52, subfamily L, member ...    32   2.2  
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    31   2.8  
gi|34577120 mitochondrial translational release factor 1 [Homo s...    31   2.8  
gi|195947369 junction-mediating and regulatory protein [Homo sap...    31   3.7  
gi|188219559 protein phosphatase 1, regulatory subunit 15B [Homo...    30   6.3  
gi|20127448 DNA-directed DNA polymerase alpha 2 [Homo sapiens]         30   8.2  
gi|7705415 hook homolog 1 [Homo sapiens]                               30   8.2  
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    30   8.2  
gi|150378505 hypothetical protein LOC285343 isoform 1 [Homo sapi...    30   8.2  
gi|40807471 transcription termination factor, RNA polymerase II ...    30   8.2  
gi|65506789 solute carrier family 26, member 10 [Homo sapiens]         30   8.2  
gi|155969701 espin-like [Homo sapiens]                                 30   8.2  

>gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo sapiens]
          Length = 597

 Score = 1221 bits (3160), Expect = 0.0
 Identities = 597/597 (100%), Positives = 597/597 (100%)

Query: 1   MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL 60
           MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL
Sbjct: 1   MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL 60

Query: 61  LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT 120
           LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT
Sbjct: 61  LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT 120

Query: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180
           HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE
Sbjct: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180

Query: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV 240
           LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV
Sbjct: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV 240

Query: 241 EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV 300
           EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV
Sbjct: 241 EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV 300

Query: 301 APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF 360
           APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF
Sbjct: 301 APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF 360

Query: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420
           IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV
Sbjct: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420

Query: 421 SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV 480
           SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV
Sbjct: 421 SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV 480

Query: 481 QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI 540
           QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI
Sbjct: 481 QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI 540

Query: 541 TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVF 597
           TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVF
Sbjct: 541 TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQVF 597


>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
          Length = 4753

 Score = 1219 bits (3154), Expect = 0.0
 Identities = 596/596 (100%), Positives = 596/596 (100%)

Query: 1   MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL 60
           MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL
Sbjct: 1   MVPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLEL 60

Query: 61  LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT 120
           LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT
Sbjct: 61  LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLPFLEQLYCWAPWVQT 120

Query: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180
           HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE
Sbjct: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180

Query: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV 240
           LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV
Sbjct: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIPVRYESSDTDNAEV 240

Query: 241 EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV 300
           EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV
Sbjct: 241 EPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYLKKIHFLYLNV 300

Query: 301 APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF 360
           APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF
Sbjct: 301 APSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGSETMTLGTWHHHCVLWQQLQF 360

Query: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420
           IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV
Sbjct: 361 IPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSV 420

Query: 421 SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV 480
           SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV
Sbjct: 421 SWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERV 480

Query: 481 QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI 540
           QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI
Sbjct: 481 QNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQI 540

Query: 541 TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQV 596
           TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQV
Sbjct: 541 TSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVENMIQTLTGGLQSVKTSALQV 596


>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
          Length = 4158

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 64/294 (21%), Positives = 124/294 (42%), Gaps = 30/294 (10%)

Query: 284 LKMERYLKKIHFLYLNVAPSRY---FRPYSLMVVPPDKVNP-EHYIFSPFGILHVHPVEG 339
           +K+ R  + + FLY+  A  R    +  Y+L VV  + +N  ++Y  S   + H++  E 
Sbjct: 190 IKIIRENEHLGFLYMIPAVPRSSIEYDTYNLKVVSYENINKNDYYTISQRAVTHIYN-ED 248

Query: 340 SETMTLGTWHHHCVLWQQLQFIPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLA 399
            E + +  W    +  ++L  IP F      K+F+ W+KNVR + +   QK L+ +L + 
Sbjct: 249 IEFIEIDRWEQEYLYHRELTKIPIFSLFRKWKAFSVWRKNVRSKKITGCQKSLQKNLFIV 308

Query: 400 VPHFGAGLLHISRL-----------LQELHSVSWLPQELDRCYELLDLQTALAEEKHKAL 448
            PH    LL I+ L           +++ H+ +    +  +   L ++   L E +++A 
Sbjct: 309 NPHLRPALLKINELCYHLSFMGLCYIEKCHTYTLQEFKAAQVIRLAEVTERLGEFRNEAK 368

Query: 449 RLLHRCLNLCTSILRLVHED-------TYHMQQCLQERVQNCDRIRTGQGSIYLQRVQHK 501
            ++ R           V +D        YH  Q     +     + T     Y    +  
Sbjct: 369 YVVRRACRFALRAAGFVPDDCAFGPFEDYHKVQSSGSFINTPHELPT-----YGDSEKMT 423

Query: 502 QLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKP 555
             EQ  K+   + ++L  F RL DY+I  ++  +    + S + ++    ++ P
Sbjct: 424 YTEQASKR--HYCMRLTCFIRLNDYLIENTMHILTVNAVNSLLNHLTDKLKRTP 475


>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
           sapiens]
          Length = 4515

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 60/281 (21%), Positives = 106/281 (37%), Gaps = 46/281 (16%)

Query: 301 APSRYFRPYSLMVVPPDKVN--PEHYIFSPFGILHVHPVEGS----ETMTLGTW---HHH 351
           +P   + PY L VV         E ++ +   I  V  + GS    E +    W     H
Sbjct: 183 SPKSLYNPYDLQVVSAHTAKHCKEFWVITASFISKVINIVGSVKEVELIPTLEWLSERRH 242

Query: 352 CVLWQQLQFIPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHIS 411
             L +Q +    F+   + K+F  WK NV+     + + FL +HL LA   F   L++I 
Sbjct: 243 YYLLRQFKIFSDFR---MNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQTCLVYIR 299

Query: 412 RLLQE-------------LHSVSWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLC 458
            L ++             L ++  +  +  R Y L +      ++  +AL+ L    N  
Sbjct: 300 GLCEDAINLKNYNDHENNLSAICLVKLDSSRTYSLDEFCEEQLQQATQALKQLEDIRNKA 359

Query: 459 TSILR---LVHEDTYHMQQCLQERVQNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWL 515
            S ++   L   +   +++  + ++   D               H +L +  +  E ++ 
Sbjct: 360 ISEMKSTFLKVAEKNEIKEYFESKLSEDD-------------TTHFKLPKYRRLLETFF- 405

Query: 516 QLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKPF 556
              KF  LVDY I Q LI  L     + +  +       PF
Sbjct: 406 ---KFVMLVDY-IFQELIRQLMNTAVTLLLELFNGSAGMPF 442


>gi|223555933 dynein, axonemal, heavy polypeptide 14 isoform 2 [Homo
           sapiens]
          Length = 453

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 60/281 (21%), Positives = 106/281 (37%), Gaps = 46/281 (16%)

Query: 301 APSRYFRPYSLMVVPPDKVN--PEHYIFSPFGILHVHPVEGS----ETMTLGTW---HHH 351
           +P   + PY L VV         E ++ +   I  V  + GS    E +    W     H
Sbjct: 183 SPKSLYNPYDLQVVSAHTAKHCKEFWVITASFISKVINIVGSVKEVELIPTLEWLSERRH 242

Query: 352 CVLWQQLQFIPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFGAGLLHIS 411
             L +Q +    F+   + K+F  WK NV+     + + FL +HL LA   F   L++I 
Sbjct: 243 YYLLRQFKIFSDFR---MNKAFVTWKLNVKRIKTEKSRSFLYHHLFLADDLFQTCLVYIR 299

Query: 412 RLLQE-------------LHSVSWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLC 458
            L ++             L ++  +  +  R Y L +      ++  +AL+ L    N  
Sbjct: 300 GLCEDAINLKNYNDHENNLSAICLVKLDSSRTYSLDEFCEEQLQQATQALKQLEDIRNKA 359

Query: 459 TSILR---LVHEDTYHMQQCLQERVQNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWL 515
            S ++   L   +   +++  + ++   D               H +L +  +  E ++ 
Sbjct: 360 ISEMKSTFLKVAEKNEIKEYFESKLSEDD-------------TTHFKLPKYRRLLETFF- 405

Query: 516 QLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKPF 556
              KF  LVDY I Q LI  L     + +  +       PF
Sbjct: 406 ---KFVMLVDY-IFQELIRQLMNTAVTLLLELFNGSAGMPF 442


>gi|24497531 Ellis van Creveld syndrome protein [Homo sapiens]
          Length = 992

 Score = 37.0 bits (84), Expect = 0.052
 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 17/117 (14%)

Query: 432 ELLDLQTALAEEKHKA-LRLLHRCL-----------NLCTSILRLVHEDTYHMQQCLQER 479
           +LL L TAL +EKH   +++   CL            L   IL    +D   +++ LQ +
Sbjct: 220 DLLHLDTALRQEKHMMFIQIFKMCLLDLLPKKKSDDELYQKILSKQEKDLEELEKGLQVK 279

Query: 480 VQNCDRIRTGQGS-IYLQRVQHKQ---LEQKLKQAEAWWLQLGKFAR-LVDYMICQS 531
           + N +    G    I L  V+ K+    EQ +   EA+W Q+      LVD   C S
Sbjct: 280 LSNTEMSGAGDSEYITLADVEKKEREYSEQLIDNMEAFWKQMANIQHFLVDQFKCSS 336


>gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]
          Length = 663

 Score = 36.2 bits (82), Expect = 0.088
 Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 40/229 (17%)

Query: 109 EQLYCWAPWVQTHLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFV 168
           +Q+YCWA W +                    L  +A   D  P   R H          +
Sbjct: 136 QQIYCWATWKE-----------------GLPLTIAADRKDDLPPNMRFHEEKR------L 172

Query: 169 QAQWSRQQVKEELATWLRPLTLPELQRCLG-----IVGAQVALEEAV---WLDG-LSLLP 219
             +W+ +    E+A   R  TL     CL        G + AL E V   W D  L    
Sbjct: 173 DFEWTLKAGALEMAL-KRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQ 231

Query: 220 LALAADIPVRYESSDTDNAEVEPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQ 279
               A+  +   S+   +  V P G +E ++QL      EK  Q  S  F  +   LD  
Sbjct: 232 FLNGANPMLLRRSTSLPSRLVLPSGMEELQAQL------EKELQNGSL-FEADFILLDGI 284

Query: 280 VMTALKMERYLKKIHFLYLNVAPSRYFRPYSLMVVPPDKVNPEHYIFSP 328
               ++ E+       + L + P+   +P  + + PP+  +P   +F P
Sbjct: 285 PANVIRGEKQYLAAPLVMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLP 333


>gi|224586817 golgi apparatus protein 1 isoform 3 [Homo sapiens]
          Length = 1179

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/127 (20%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 441 AEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQ-----CLQERVQNCDRIRTGQGSIYL 495
           AEE+   +++   C      +  L  +D +H+ +     C  +R + C+  + G+G +Y 
Sbjct: 278 AEEREPKIQVSELCKKAILRVAELSSDD-FHLDRHLYFACRDDRERFCENTQAGEGRVYK 336

Query: 496 QRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKP 555
               HK  E+ + +     L   +     DY +  SL    +  +  +  N+   PR + 
Sbjct: 337 CLFNHK-FEESMSEKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSRE 395

Query: 556 FLSSQLV 562
              S L+
Sbjct: 396 ARLSYLL 402


>gi|224586815 golgi apparatus protein 1 isoform 2 [Homo sapiens]
          Length = 1192

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/127 (20%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 441 AEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQ-----CLQERVQNCDRIRTGQGSIYL 495
           AEE+   +++   C      +  L  +D +H+ +     C  +R + C+  + G+G +Y 
Sbjct: 267 AEEREPKIQVSELCKKAILRVAELSSDD-FHLDRHLYFACRDDRERFCENTQAGEGRVYK 325

Query: 496 QRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKP 555
               HK  E+ + +     L   +     DY +  SL    +  +  +  N+   PR + 
Sbjct: 326 CLFNHK-FEESMSEKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSRE 384

Query: 556 FLSSQLV 562
              S L+
Sbjct: 385 ARLSYLL 391


>gi|54633312 golgi apparatus protein 1 isoform 1 [Homo sapiens]
          Length = 1203

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/127 (20%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 441 AEEKHKALRLLHRCLNLCTSILRLVHEDTYHMQQ-----CLQERVQNCDRIRTGQGSIYL 495
           AEE+   +++   C      +  L  +D +H+ +     C  +R + C+  + G+G +Y 
Sbjct: 278 AEEREPKIQVSELCKKAILRVAELSSDD-FHLDRHLYFACRDDRERFCENTQAGEGRVYK 336

Query: 496 QRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQITSFVANILQAPRQKP 555
               HK  E+ + +     L   +     DY +  SL    +  +  +  N+   PR + 
Sbjct: 337 CLFNHK-FEESMSEKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSRE 395

Query: 556 FLSSQLV 562
              S L+
Sbjct: 396 ARLSYLL 402


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform
           5 [Homo sapiens]
          Length = 6907

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 47/229 (20%), Positives = 86/229 (37%), Gaps = 39/229 (17%)

Query: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180
           H H++ L   +       SL D  S  D  P        PP   C  VQA+W +   ++ 
Sbjct: 134 HFHIEKLAQTLSCNYNQPSL-DDVSVVDSSPASS-----PPAKKCSKVQARW-QMSARKA 186

Query: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPL--ALAADI----PVRYESSD 234
           L  W +       ++C       V   ++ W +G++ L +  AL  D+     V++ S+ 
Sbjct: 187 LLLWAQ-------EQCATYESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNK 239

Query: 235 TDNAEVEPVGRKETR-------SQLDYEVPREKA----------FQKSSTGFSPETSFLD 277
            +  E   +  +E +         +D   P EK+          + K + G   E     
Sbjct: 240 DNLREAFRIAEQELKIPRLLEPEDVDVVDPDEKSIMTYVAQFLQYSKDAPGTGEEAQGKV 299

Query: 278 SQVMTALKMERYLKKIHFLYLNVAPSRYFRPYSLMVVPPDKVNPEHYIF 326
              M  L +++  +K+  L  +     YF+ Y+ ++   +  N E   F
Sbjct: 300 KDAMGWLTLQK--EKLQKLLKDSENDTYFKKYNSLLSFMESFNEEKKSF 346


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform
           1 [Homo sapiens]
          Length = 6885

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 47/229 (20%), Positives = 86/229 (37%), Gaps = 39/229 (17%)

Query: 121 HLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKEE 180
           H H++ L   +       SL D  S  D  P        PP   C  VQA+W +   ++ 
Sbjct: 134 HFHIEKLAQTLSCNYNQPSL-DDVSVVDSSPASS-----PPAKKCSKVQARW-QMSARKA 186

Query: 181 LATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPL--ALAADI----PVRYESSD 234
           L  W +       ++C       V   ++ W +G++ L +  AL  D+     V++ S+ 
Sbjct: 187 LLLWAQ-------EQCATYESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNK 239

Query: 235 TDNAEVEPVGRKETR-------SQLDYEVPREKA----------FQKSSTGFSPETSFLD 277
            +  E   +  +E +         +D   P EK+          + K + G   E     
Sbjct: 240 DNLREAFRIAEQELKIPRLLEPEDVDVVDPDEKSIMTYVAQFLQYSKDAPGTGEEAQGKV 299

Query: 278 SQVMTALKMERYLKKIHFLYLNVAPSRYFRPYSLMVVPPDKVNPEHYIF 326
              M  L +++  +K+  L  +     YF+ Y+ ++   +  N E   F
Sbjct: 300 KDAMGWLTLQK--EKLQKLLKDSENDTYFKKYNSLLSFMESFNEEKKSF 346


>gi|145046269 rotatin [Homo sapiens]
          Length = 2226

 Score = 32.7 bits (73), Expect = 0.97
 Identities = 39/140 (27%), Positives = 64/140 (45%), Gaps = 18/140 (12%)

Query: 383  QGLHRLQKFLENHLLLAVPHFGAGLLHIS-------RLLQELHSVSWLPQELDRCYELLD 435
            +G+ +   FL+N L LA+P    G  H+S       +LL  + S     Q + R    LD
Sbjct: 2046 KGVIQKSNFLQNFLSLALPK--GGNKHLSNLTILWLKLLLNISSGEDGQQMILRLDGCLD 2103

Query: 436  LQTALAEEKHKALRLLHRCL--NLCTSILR----LVHEDTYH-MQQCLQERVQNCDRIRT 488
            L T +++ KHK+  LL   +  N+C S       L +E     +  CL+   QN  RI  
Sbjct: 2104 LLTEMSKYKHKSSPLLPLLIFHNVCFSPANKPKILANEKVITVLAACLESENQNAQRI-- 2161

Query: 489  GQGSIYLQRVQHKQLEQKLK 508
            G  +++     +++ +  LK
Sbjct: 2162 GAAALWALIYNYQKAKTALK 2181


>gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1
           [Homo sapiens]
          Length = 854

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 14/74 (18%)

Query: 179 EELATWLRPLTLPELQRCLGIVGAQ---------VALEEAVWLDGLSL---LPLALAADI 226
           E L TW  PL+ PEL+  L   G           ++L E  W D ++L   +   LA  +
Sbjct: 253 ERLITWYNPLSAPELE--LDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQL 310

Query: 227 PVRYESSDTDNAEV 240
           P R+++++    EV
Sbjct: 311 PARFKNTEAIGNEV 324


>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
            [Homo sapiens]
          Length = 2044

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 14/74 (18%)

Query: 179  EELATWLRPLTLPELQRCLGIVGAQ---------VALEEAVWLDGLSL---LPLALAADI 226
            E L TW  PL+ PEL+  L   G           ++L E  W D ++L   +   LA  +
Sbjct: 1443 ERLITWYNPLSAPELE--LDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQL 1500

Query: 227  PVRYESSDTDNAEV 240
            P R+++++    EV
Sbjct: 1501 PARFKNTEAIGNEV 1514


>gi|221219015 olfactory receptor, family 52, subfamily L, member 1
           [Homo sapiens]
          Length = 329

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 19/68 (27%), Positives = 33/68 (48%)

Query: 281 MTALKMERYLKKIHFLYLNVAPSRYFRPYSLMVVPPDKVNPEHYIFSPFGILHVHPVEGS 340
           MT +    +L K   + L+ +  R  +P  L+V  P     +H+I  P GIL++  + G+
Sbjct: 1   MTLVSFFSFLSKPLIMLLSNSSWRLSQPSFLLVGIPGLEESQHWIALPLGILYLLALVGN 60

Query: 341 ETMTLGTW 348
            T+    W
Sbjct: 61  VTILFIIW 68


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 2   VPEERRVGLSSDETSSDSLKSWHSICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLELL 61
           VPE +    SSDE S  S  S  S    +S+E+ L      R+   P +    P   E+ 
Sbjct: 750 VPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRK--TPPSSKSAPATKEIS 807

Query: 62  LAELRTLFSAVLQDSSPAA 80
           L +L       +Q  SP A
Sbjct: 808 LLDLEDFTPPSVQPVSPPA 826


>gi|34577120 mitochondrial translational release factor 1 [Homo
           sapiens]
          Length = 445

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 22/157 (14%)

Query: 384 GLHRLQKFLENHLLLAVPHFGAGLLHISRLLQELHSVSWLPQELDRCYELLDLQTALAEE 443
           G+HR+Q+  E  L   +     G + +  L Q        P E+D   +  DL+     +
Sbjct: 256 GIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQ--------PDEVDVKLDPKDLRI----D 303

Query: 444 KHKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERVQNCDR---IRTGQGSIYLQRVQH 500
             +A     + +N   S +RLVH  T  + +C QER Q  ++    R  +  +Y Q ++ 
Sbjct: 304 TFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVLRARLYQQIIE- 362

Query: 501 KQLEQKLKQAEAWWLQLGKFA---RLVDYMICQSLIS 534
              + K +Q  A  LQ+G  A   R+  Y   Q  +S
Sbjct: 363 ---KDKRQQQSARKLQVGTRAQSERIRTYNFTQDRVS 396


>gi|195947369 junction-mediating and regulatory protein [Homo
           sapiens]
          Length = 988

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 16/87 (18%)

Query: 435 DLQTALAEEKHKALRLLHRCLNL-CTSILRLVHE--------DTYHMQQCLQERVQNCDR 485
           DLQ  L E + + L+     L     SI RL+ E        DTY   + + E+ +    
Sbjct: 532 DLQLQLYEVQFEILKCEELLLTAQLESIKRLISEKRDEVVYYDTYESMEAMLEKEEMA-- 589

Query: 486 IRTGQGSIYLQRVQHKQLEQKLKQAEA 512
                 S YLQR + ++L+QK +Q EA
Sbjct: 590 -----ASAYLQREELQKLQQKARQLEA 611


>gi|188219559 protein phosphatase 1, regulatory subunit 15B [Homo
           sapiens]
          Length = 713

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 11  SSDETSSDSLKSWHSICVLDSKEQPL---ACQQKQRQFVKPVTESEQPTVLELLLAELRT 67
           S+DE  ++SLK W+S C  D    PL   A  Q   +  K   +S+ P+   + ++E  T
Sbjct: 546 SADE--AESLKLWNSFCNSDDPYNPLNFKAPFQTSGENEKGCRDSKTPSESIVAISECHT 603

Query: 68  LFSAVLQ 74
           L S  +Q
Sbjct: 604 LLSCKVQ 610


>gi|20127448 DNA-directed DNA polymerase alpha 2 [Homo sapiens]
          Length = 598

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 14/37 (37%), Positives = 18/37 (48%)

Query: 143 SASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKE 179
           S SH    P  R +HH P  P  PF  +  SR+  K+
Sbjct: 416 SGSHLVFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQ 452


>gi|7705415 hook homolog 1 [Homo sapiens]
          Length = 728

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 43/192 (22%), Positives = 80/192 (41%), Gaps = 46/192 (23%)

Query: 368 LLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAV------------PHFGAGLLH--ISRL 413
           +L  +  C KK   +Q +  L++ +++ ++ A+            P+   G L   + R 
Sbjct: 124 ILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRA 183

Query: 414 LQELHSVSWLPQELDRCYELLDLQ-TALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHM 472
           L+EL       +EL +  E LD+Q T L +EK+                  LV E+    
Sbjct: 184 LEELQEALAEKEELRQRCEELDMQVTTLQDEKNS-----------------LVSEN---- 222

Query: 473 QQCLQERVQNCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMI-CQS 531
            + + E++   D       ++  ++  H QL+ +  Q E + L+  K     DY + C+ 
Sbjct: 223 -EMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAK----DDYRVHCEE 277

Query: 532 LISVLEEQITSF 543
               LE+Q+  F
Sbjct: 278 ----LEKQLIEF 285


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 16/92 (17%)

Query: 168  VQAQWSRQQVKEELATWLRPLTLPELQRCLGIVGAQVALEEAVWLDGLSLLPLALAADIP 227
            ++ Q SR++++E  A  LRPL+ P  Q C+     +             L P    + +P
Sbjct: 3076 LRRQLSRERLEEAPAPVLRPLSRPGSQECMDAAPGR-------------LEPKDRGSTLP 3122

Query: 228  VRYESSDTDNAEVEPVGRKETRSQLDYEVPRE 259
             R    D   A     GR  +R  LD   PRE
Sbjct: 3123 RRQPPRDYPGA---MAGRFGSRDALDLGAPRE 3151


>gi|150378505 hypothetical protein LOC285343 isoform 1 [Homo
           sapiens]
          Length = 496

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 33/126 (26%), Positives = 56/126 (44%), Gaps = 13/126 (10%)

Query: 423 LPQELDRCYELLDLQTALAEEK-HKALRLLHRCLNLCTSILRLVHEDTYHMQQCLQERVQ 481
           L +ELDR  + L  Q  L++ +  ++  + HRC  L  S+ RL  ++   ++     + +
Sbjct: 211 LRKELDRLKDELSHQLQLSDIRWQRSWGIAHRCSQL-HSLSRLAQQNLETLK-----KAK 264

Query: 482 NCDRIRTGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGKFARLVDYMICQSLISVLEEQIT 541
            C  I T +    +  V H  L          W +L  F RL  Y   Q  + +LE+QI+
Sbjct: 265 GCTIIFTDRSG--MSAVGHVMLGTM--DVHHHWTKL--FERLPSYFDLQRRLMILEDQIS 318

Query: 542 SFVANI 547
             +  I
Sbjct: 319 YLLGGI 324


>gi|40807471 transcription termination factor, RNA polymerase II [Homo
            sapiens]
          Length = 1162

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 15/44 (34%), Positives = 24/44 (54%)

Query: 26   ICVLDSKEQPLACQQKQRQFVKPVTESEQPTVLELLLAELRTLF 69
            +C    +E+ L  Q+K++   K V      +V +L LA+LR LF
Sbjct: 1117 VCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLF 1160


>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
          Length = 563

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 11/85 (12%)

Query: 61  LLAELRTLFSAVLQDSSPAAWRYLHAVLGLLPPYRELLVGHLDLLP----------FLEQ 110
           L   L +L +A L  SSPA        L LL P +EL V   D LP           L  
Sbjct: 183 LFKTLASLLTA-LPRSSPAELTISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLAS 241

Query: 111 LYCWAPWVQTHLHLDLLGAIVQAFP 135
           + C+   V T   + ++G +   FP
Sbjct: 242 VLCFTSSVDTRYQVQIVGLLPGGFP 266


>gi|155969701 espin-like [Homo sapiens]
          Length = 1005

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 9/71 (12%)

Query: 47  KPVTESEQPTVLELLLAELRTLFSAVLQDSS-------PAAWRYLHAVLGLLPPYRELLV 99
           +P+ E ++  ++  L A L    SA  QD+         AAWRY      +L P+ ELL 
Sbjct: 444 QPIPEWKRQVMVRKLQARLGAESSAEAQDNGGSSGPTEQAAWRYSQTHQAILGPFGELLT 503

Query: 100 GHLDLLPFLEQ 110
              D L +LE+
Sbjct: 504 E--DDLVYLEK 512


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,189,216
Number of Sequences: 37866
Number of extensions: 1136063
Number of successful extensions: 2845
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2829
Number of HSP's gapped (non-prelim): 39
length of query: 597
length of database: 18,247,518
effective HSP length: 108
effective length of query: 489
effective length of database: 14,157,990
effective search space: 6923257110
effective search space used: 6923257110
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.