Guide to the Human Genome
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Name: POLA2 Sequence: fasta or formatted (598aa) NCBI GI: 20127448
Description:

DNA-directed DNA polymerase alpha 2

Referenced in:

DNA Polymerases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         30           2
 C cysteine            2.5         15           1
 D aspartate           4.3         26           1
 E glutamate           8.5         51           5
 F phenylalanine       4.0         24           1
 G glycine             6.9         41           2
 H histidine           2.3         14           2
 I isoleucine          5.9         35           2
 K lysine              4.5         27           2
 L leucine            10.7         64           2
 M methionine          1.0          6           1
 N asparagine          2.3         14           2
 P proline             6.2         37           2
 Q glutamine           4.7         28           2
 R arginine            4.5         27           2
 S serine             10.5         63           4
 T threonine           5.5         33           2
 V valine              7.0         42           2
 W tryptophan          0.2          1           1
 Y tyrosine            3.3         20           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA-directed DNA polymerase alpha 2 
POLE2                 0.015   DNA-directed DNA polymerase epsilon 2 
ATF7                  0.009   activating transcription factor 7 isoform 1 
LMNB2                 0.009   lamin B2 
ATF7                  0.007   activating transcription factor 7 isoform 2 
PRG4                  0.006   proteoglycan 4 isoform D 
PRG4                  0.006   proteoglycan 4 isoform C 
PRG4                  0.006   proteoglycan 4 isoform B 
PRG4                  0.006   proteoglycan 4 isoform A 
MADD                  0.006   MAP-kinase activating death domain-containing prote...
MADD                  0.006   MAP-kinase activating death domain-containing prote...
MADD                  0.006   MAP-kinase activating death domain-containing prote...
MADD                  0.006   MAP-kinase activating death domain-containing prote...
MADD                  0.006   MAP-kinase activating death domain-containing prote...
MADD                  0.006   MAP-kinase activating death domain-containing prote...
MLL3                  0.006   myeloid/lymphoid or mixed-lineage leukemia 3 
EBF3                  0.006   early B-cell factor 3 
LGALS12               0.006   lectin, galactoside-binding, soluble, 12 isoform 5 ...
LGALS12               0.006   lectin, galactoside-binding, soluble, 12 isoform 3 ...
YES1                  0.005   viral oncogene yes-1 homolog 1 
FARP2                 0.005   FERM, RhoGEF and pleckstrin domain protein 2 
LOC100128719          0.004   PREDICTED: hypothetical protein, partial 
LOC100128719          0.004   PREDICTED: hypothetical protein, partial 
VPS37A                0.004   hepatocellular carcinoma related protein 1 isoform ...
VPS37A                0.004   hepatocellular carcinoma related protein 1 isoform ...
ATF7                  0.004   activating transcription factor 7 isoform 3 
SPEG                  0.004   SPEG complex locus 
DNHD1                 0.004   dynein heavy chain domain 1 isoform 1 
LOC728347             0.004   PREDICTED: hypothetical protein 
C12orf55              0.004   PREDICTED: chromosome 12 open reading frame 55 [Hom...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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