Guide to the Human Genome
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Search of human proteins with 222136686

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222136686 melanocyte-specific gene 1 isoform 1 [Homo
sapiens]
         (193 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222136692 melanocyte-specific gene 1 isoform 1 [Homo sapiens]      391   e-109
gi|222136690 melanocyte-specific gene 1 isoform 1 [Homo sapiens]      391   e-109
gi|222136688 melanocyte-specific gene 1 isoform 2 [Homo sapiens]      391   e-109
gi|222136686 melanocyte-specific gene 1 isoform 1 [Homo sapiens]      391   e-109
gi|19923343 Cbp/p300-interacting transactivator, with Glu/Asp-ri...    93   1e-19
gi|19263349 Cbp/p300-interacting transactivator, with Glu/Asp-ri...    74   6e-14
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]             39   0.003
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]             39   0.004
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]             38   0.005
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]             38   0.005
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    38   0.005
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    38   0.005
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    38   0.005
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    38   0.005
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]             37   0.010
gi|239047795 pleckstrin homology domain containing, family A mem...    36   0.018
gi|26667219 eyes absent 1 isoform c [Homo sapiens]                     36   0.023
gi|130502140 NEZHA isoform 2 [Homo sapiens]                            35   0.030
gi|122937255 NEZHA isoform 1 [Homo sapiens]                            35   0.030
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    35   0.030
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]    35   0.040
gi|122937321 UNC homeobox [Homo sapiens]                               35   0.040
gi|5174711 T-box 1 isoform B [Homo sapiens]                            35   0.052
gi|18104952 T-box 1 isoform C [Homo sapiens]                           35   0.052
gi|18104950 T-box 1 isoform A [Homo sapiens]                           35   0.052
gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo ...    35   0.052
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]             34   0.068
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]             34   0.068
gi|150170670 piccolo isoform 2 [Homo sapiens]                          34   0.068
gi|150378539 piccolo isoform 1 [Homo sapiens]                          34   0.068

>gi|222136692 melanocyte-specific gene 1 isoform 1 [Homo sapiens]
          Length = 193

 Score =  391 bits (1004), Expect = e-109
 Identities = 193/193 (100%), Positives = 193/193 (100%)

Query: 1   MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 60
           MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
Sbjct: 1   MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 60

Query: 61  PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 120
           PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
Sbjct: 61  PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 120

Query: 121 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 180
           LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
Sbjct: 121 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 180

Query: 181 NEFDFTADFPSSC 193
           NEFDFTADFPSSC
Sbjct: 181 NEFDFTADFPSSC 193


>gi|222136690 melanocyte-specific gene 1 isoform 1 [Homo sapiens]
          Length = 193

 Score =  391 bits (1004), Expect = e-109
 Identities = 193/193 (100%), Positives = 193/193 (100%)

Query: 1   MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 60
           MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
Sbjct: 1   MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 60

Query: 61  PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 120
           PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
Sbjct: 61  PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 120

Query: 121 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 180
           LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
Sbjct: 121 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 180

Query: 181 NEFDFTADFPSSC 193
           NEFDFTADFPSSC
Sbjct: 181 NEFDFTADFPSSC 193


>gi|222136688 melanocyte-specific gene 1 isoform 2 [Homo sapiens]
          Length = 219

 Score =  391 bits (1004), Expect = e-109
 Identities = 193/193 (100%), Positives = 193/193 (100%)

Query: 1   MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 60
           MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
Sbjct: 27  MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 86

Query: 61  PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 120
           PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
Sbjct: 87  PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 146

Query: 121 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 180
           LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
Sbjct: 147 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 206

Query: 181 NEFDFTADFPSSC 193
           NEFDFTADFPSSC
Sbjct: 207 NEFDFTADFPSSC 219


>gi|222136686 melanocyte-specific gene 1 isoform 1 [Homo sapiens]
          Length = 193

 Score =  391 bits (1004), Expect = e-109
 Identities = 193/193 (100%), Positives = 193/193 (100%)

Query: 1   MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 60
           MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
Sbjct: 1   MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA 60

Query: 61  PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 120
           PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
Sbjct: 61  PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 120

Query: 121 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 180
           LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
Sbjct: 121 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ 180

Query: 181 NEFDFTADFPSSC 193
           NEFDFTADFPSSC
Sbjct: 181 NEFDFTADFPSSC 193


>gi|19923343 Cbp/p300-interacting transactivator, with Glu/Asp-rich
           carboxy-terminal domain, 2 [Homo sapiens]
          Length = 270

 Score = 93.2 bits (230), Expect = 1e-19
 Identities = 60/174 (34%), Positives = 78/174 (44%), Gaps = 35/174 (20%)

Query: 48  PGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLL--------------- 92
           P    N ++  G P +S G  + +           FN HP PH                 
Sbjct: 89  PAARFNNSQFMGPPVASQGGSLPASMQLQKLNNQYFNHHPYPHNHYMPDLHPAAGHQMNG 148

Query: 93  ASMHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQS-------- 144
            + H +  N ++ G  ++TPG  G  G       G+ +GG    S S G           
Sbjct: 149 TNQHFRDCNPKHSG-GSSTPG--GSGGSSTPGGSGSSSGGGAGSSNSGGGSGSGNMPASV 205

Query: 145 ---------PAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADF 189
                    P +ID+D +DEEVLMSLV+E+GLDR  ELPELWLGQNEFDF  DF
Sbjct: 206 AHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDF 259


>gi|19263349 Cbp/p300-interacting transactivator, with Glu/Asp-rich
           carboxy-terminal domain, 4 [Homo sapiens]
          Length = 184

 Score = 74.3 bits (181), Expect = 6e-14
 Identities = 61/171 (35%), Positives = 77/171 (45%), Gaps = 32/171 (18%)

Query: 41  AVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPP------------SFNLHPA 88
           + A  H P         +G    S   P G+P   PP + P            SF   PA
Sbjct: 19  SAAAAHGPHALRTLPPYAGPGLDSGLRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPA 78

Query: 89  --PHLLASMHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPA 146
             P      HLQ + + Y G AAA P  PG  GP      G Q       +PSA A  P 
Sbjct: 79  VPPPAAGIAHLQPVATPYPGRAAAPPNAPG--GPP-----GPQP------APSAAAPPPP 125

Query: 147 I-----IDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSS 192
                 +D++ +DEE L SL +ELGL R  ELPEL+LGQ+EFD  +D  S+
Sbjct: 126 AHALGGMDAELIDEEALTSLELELGLHRVRELPELFLGQSEFDCFSDLGSA 176


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 48/211 (22%), Positives = 68/211 (32%), Gaps = 41/211 (19%)

Query: 2   PTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAP 61
           P+ + PA   KG  SP+  D +   +              + + H P  A   T  +  P
Sbjct: 254 PSDNAPA---KGNKSPSPPDGSPAATP------------EIRVNHEPEPAGGATPGATLP 298

Query: 62  TSSSGSPIGSPTTTPPTKPPSFNL-----------------------HPAPHLLASMHLQ 98
            S S    G P   PP   PS  +                        P      S+   
Sbjct: 299 KSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPTESPAGSLPSG 358

Query: 99  KLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVL 158
           + ++     A + P Q  E GP Q  +    AGG +   P+AGAQ P    +       L
Sbjct: 359 EPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQ---PAAGAQEPGETAASEAASSSL 415

Query: 159 MSLVVELGLDRANELPELWLGQNEFDFTADF 189
            ++VVE      N   E   G    D    F
Sbjct: 416 PAVVVETFPATVNGTVEGGSGAGRLDLPPGF 446


>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
          Length = 482

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 46/188 (24%), Positives = 67/188 (35%), Gaps = 31/188 (16%)

Query: 2   PTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAP 61
           P+ + PA   KG  SP+  D +   +              + + H P  A   T  +  P
Sbjct: 254 PSDNAPA---KGNKSPSPPDGSPAATP------------EIRVNHEPEPAGGATPGATLP 298

Query: 62  TSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGPL 121
            S S    G P   PP   PS  +     +L+       ++    ++  TP QP EA  +
Sbjct: 299 KSPSQLRKGPPVPPPPKHTPSKEV-KQEQILSLFE----DTFVPEISVTTPSQPAEASEV 353

Query: 122 QNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQN 181
                   AGG +   P+AGAQ P    +       L ++VVE      N   E   G  
Sbjct: 354 --------AGGTQ---PAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 402

Query: 182 EFDFTADF 189
             D    F
Sbjct: 403 RLDLPPGF 410


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 46/188 (24%), Positives = 64/188 (34%), Gaps = 38/188 (20%)

Query: 2   PTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAP 61
           P+ + PA   KG  SP+  D +   +              + + H P  A   T  +  P
Sbjct: 254 PSDNAPA---KGNKSPSPPDGSPAATP------------EIRVNHEPEPAGGATPGATLP 298

Query: 62  TSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGPL 121
            S S  P  SP  + P+  PS                   +     A + P Q  E GP 
Sbjct: 299 KSPS-QPTESPAGSLPSGEPS-------------------AAEGTFAVSWPSQTAEPGPA 338

Query: 122 QNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQN 181
           Q  +    AGG +   P+AGAQ P    +       L ++VVE      N   E   G  
Sbjct: 339 QPAEASEVAGGTQ---PAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 395

Query: 182 EFDFTADF 189
             D    F
Sbjct: 396 RLDLPPGF 403


>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 46/188 (24%), Positives = 64/188 (34%), Gaps = 38/188 (20%)

Query: 2   PTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAP 61
           P+ + PA   KG  SP+  D +   +              + + H P  A   T  +  P
Sbjct: 285 PSDNAPA---KGNKSPSPPDGSPAATP------------EIRVNHEPEPAGGATPGATLP 329

Query: 62  TSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGPL 121
            S S  P  SP  + P+  PS                   +     A + P Q  E GP 
Sbjct: 330 KSPS-QPTESPAGSLPSGEPS-------------------AAEGTFAVSWPSQTAEPGPA 369

Query: 122 QNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQN 181
           Q  +    AGG +   P+AGAQ P    +       L ++VVE      N   E   G  
Sbjct: 370 QPAEASEVAGGTQ---PAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAG 426

Query: 182 EFDFTADF 189
             D    F
Sbjct: 427 RLDLPPGF 434


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 50  VASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAA 109
           +A +G K    P    GSP GSP    P  PP +     P L  +          QG+  
Sbjct: 586 LALSGEKGDQGPPGDPGSP-GSPGPAGPAGPPGYGPQGEPGLQGT----------QGVPG 634

Query: 110 ATPGQPGEAGP 120
           A PG PGEAGP
Sbjct: 635 A-PGPPGEAGP 644


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 50  VASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAA 109
           +A +G K    P    GSP GSP    P  PP +     P L  +          QG+  
Sbjct: 586 LALSGEKGDQGPPGDPGSP-GSPGPAGPAGPPGYGPQGEPGLQGT----------QGVPG 634

Query: 110 ATPGQPGEAGP 120
           A PG PGEAGP
Sbjct: 635 A-PGPPGEAGP 644


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 50  VASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAA 109
           +A +G K    P    GSP GSP    P  PP +     P L  +          QG+  
Sbjct: 586 LALSGEKGDQGPPGDPGSP-GSPGPAGPAGPPGYGPQGEPGLQGT----------QGVPG 634

Query: 110 ATPGQPGEAGP 120
           A PG PGEAGP
Sbjct: 635 A-PGPPGEAGP 644


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 12/71 (16%)

Query: 50  VASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAA 109
           +A +G K    P    GSP GSP    P  PP +     P L  +          QG+  
Sbjct: 586 LALSGEKGDQGPPGDPGSP-GSPGPAGPAGPPGYGPQGEPGLQGT----------QGVPG 634

Query: 110 ATPGQPGEAGP 120
           A PG PGEAGP
Sbjct: 635 A-PGPPGEAGP 644


>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
          Length = 497

 Score = 37.0 bits (84), Expect = 0.010
 Identities = 38/148 (25%), Positives = 54/148 (36%), Gaps = 16/148 (10%)

Query: 42  VAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLN 101
           + + H P  A   T  +  P S S    G P   PP   PS  +     +L+       +
Sbjct: 294 IRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEV-KQEQILSLFE----D 348

Query: 102 SQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSL 161
           +    ++  TP QP EA  +        AGG +   P+AGAQ P    +       L ++
Sbjct: 349 TFVPEISVTTPSQPAEASEV--------AGGTQ---PAAGAQEPGETAASEAASSSLPAV 397

Query: 162 VVELGLDRANELPELWLGQNEFDFTADF 189
           VVE      N   E   G    D    F
Sbjct: 398 VVETFPATVNGTVEGGSGAGRLDLPPGF 425


>gi|239047795 pleckstrin homology domain containing, family A member
           7 [Homo sapiens]
          Length = 1121

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 34/116 (29%), Positives = 45/116 (38%), Gaps = 16/116 (13%)

Query: 10  DVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPI 69
           DV  G S     AN+E   +   ++   +RK V +  +P V S  T  S  P      P 
Sbjct: 817 DVTAGLS-----ANKENFRILVESVKNPERKTVPLFPHPPVPSLSTSESKPP------PQ 865

Query: 70  GSPTTTPPTKPPSFNLHP-----APHLLASMHLQKLNSQYQGMAAATPGQPGEAGP 120
            SP T+P   P    L P      P+      L+K+ S  Q    A P    EA P
Sbjct: 866 PSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVTSPLQSPTKAKPKVEDEAPP 921


>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
          Length = 557

 Score = 35.8 bits (81), Expect = 0.023
 Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 15/99 (15%)

Query: 55  TKASGAPTSSSGSPIGSPTTTP-PT---KPPSF--NLHPAPHLLASMHLQKL-------- 100
           T A G+  + SGS IGS + +P PT    PP    +  P PH+L +   Q +        
Sbjct: 55  TTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQF 114

Query: 101 -NSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSP 138
                Q  A AT  QPG+   + ++    + G ++S SP
Sbjct: 115 TTGMQQATAYATYPQPGQPYGISSYGIKTEGGLSQSQSP 153


>gi|130502140 NEZHA isoform 2 [Homo sapiens]
          Length = 1249

 Score = 35.4 bits (80), Expect = 0.030
 Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 20/113 (17%)

Query: 51  ASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPH---------------LLASM 95
           A +G    G   +  G   G PT+ P     S +L P PH                L+S+
Sbjct: 656 ADSGPVPGGERPAGEGQ--GEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSL 713

Query: 96  H--LQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPA 146
              +Q+L  Q Q + A  P  PG A P   W       G ++ SPS   + PA
Sbjct: 714 QRDMQRLTDQQQRLLAP-PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPA 765


>gi|122937255 NEZHA isoform 1 [Homo sapiens]
          Length = 1276

 Score = 35.4 bits (80), Expect = 0.030
 Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 20/113 (17%)

Query: 51  ASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPH---------------LLASM 95
           A +G    G   +  G   G PT+ P     S +L P PH                L+S+
Sbjct: 683 ADSGPVPGGERPAGEGQ--GEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSL 740

Query: 96  H--LQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPA 146
              +Q+L  Q Q + A  P  PG A P   W       G ++ SPS   + PA
Sbjct: 741 QRDMQRLTDQQQRLLAP-PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPA 792


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 35.4 bits (80), Expect = 0.030
 Identities = 28/122 (22%), Positives = 43/122 (35%), Gaps = 6/122 (4%)

Query: 54   GTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPG 113
            GT        +   P   P   PP  PP     P P     + +++  ++ +  A   P 
Sbjct: 966  GTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPT 1025

Query: 114  QPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANEL 173
               EA P Q           E  SP+AG     +++ +P     L+    E G D+    
Sbjct: 1026 LAPEALPSQG------EVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP 1079

Query: 174  PE 175
            PE
Sbjct: 1080 PE 1081


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score = 35.0 bits (79), Expect = 0.040
 Identities = 38/164 (23%), Positives = 64/164 (39%), Gaps = 15/164 (9%)

Query: 25  EMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFN 84
           E ++ A +   +  RK      +P   S    AS    +++G+ +GS  T+    PP   
Sbjct: 6   ESTAAAAAAADISARKMAHPAMFPRRGSGSGSASAL--NAAGTGVGSNATSSEDFPPPSL 63

Query: 85  LHPAPHLLASMH------LQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSP 138
           L P P   +S         Q LN   Q    A P  PG     +   F   +     +S 
Sbjct: 64  LQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISA 123

Query: 139 SAGAQSPAIIDSDPVD-------EEVLMSLVVELGLDRANELPE 175
           S  + +    D++  D       E++  S ++++ L RA +L E
Sbjct: 124 SISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGE 167


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 35.0 bits (79), Expect = 0.040
 Identities = 28/89 (31%), Positives = 33/89 (37%), Gaps = 14/89 (15%)

Query: 45  LHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQY 104
           LH PG    G     AP+S S S  G  +  PP  PP     P  H           S  
Sbjct: 219 LHSPG----GLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHA----------SGA 264

Query: 105 QGMAAATPGQPGEAGPLQNWDFGAQAGGA 133
            G A A PG+P   G      + +Q  GA
Sbjct: 265 AGTAPAPPGEPPAPGTCDPAFYPSQRSGA 293


>gi|5174711 T-box 1 isoform B [Homo sapiens]
          Length = 372

 Score = 34.7 bits (78), Expect = 0.052
 Identities = 34/135 (25%), Positives = 48/135 (35%), Gaps = 17/135 (12%)

Query: 45  LHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQY 104
           +H+  V  +    + +  SS G+  G P    P   P     P P             +Y
Sbjct: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP----------PPRY 50

Query: 105 QGMAAATPGQPGEAGPLQNWDFGAQAGGAESLS--PSAGAQSPAIIDSDPVDEEVLMSLV 162
              AAA PG PG   P   + F   AG A S +  P     S A     PV +   ++  
Sbjct: 51  DPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVA-- 108

Query: 163 VELGLDRANELPELW 177
              G+    E+  LW
Sbjct: 109 ---GVSVQLEMKALW 120


>gi|18104952 T-box 1 isoform C [Homo sapiens]
          Length = 495

 Score = 34.7 bits (78), Expect = 0.052
 Identities = 34/135 (25%), Positives = 48/135 (35%), Gaps = 17/135 (12%)

Query: 45  LHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQY 104
           +H+  V  +    + +  SS G+  G P    P   P     P P             +Y
Sbjct: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP----------PPRY 50

Query: 105 QGMAAATPGQPGEAGPLQNWDFGAQAGGAESLS--PSAGAQSPAIIDSDPVDEEVLMSLV 162
              AAA PG PG   P   + F   AG A S +  P     S A     PV +   ++  
Sbjct: 51  DPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVA-- 108

Query: 163 VELGLDRANELPELW 177
              G+    E+  LW
Sbjct: 109 ---GVSVQLEMKALW 120


>gi|18104950 T-box 1 isoform A [Homo sapiens]
          Length = 398

 Score = 34.7 bits (78), Expect = 0.052
 Identities = 34/135 (25%), Positives = 48/135 (35%), Gaps = 17/135 (12%)

Query: 45  LHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQY 104
           +H+  V  +    + +  SS G+  G P    P   P     P P             +Y
Sbjct: 1   MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP----------PPRY 50

Query: 105 QGMAAATPGQPGEAGPLQNWDFGAQAGGAESLS--PSAGAQSPAIIDSDPVDEEVLMSLV 162
              AAA PG PG   P   + F   AG A S +  P     S A     PV +   ++  
Sbjct: 51  DPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVA-- 108

Query: 163 VELGLDRANELPELW 177
              G+    E+  LW
Sbjct: 109 ---GVSVQLEMKALW 120


>gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo
           sapiens]
          Length = 539

 Score = 34.7 bits (78), Expect = 0.052
 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 7/122 (5%)

Query: 6   RPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNG---TKASGAPT 62
           R  LD +    PAKE+   E ++  Y+   V  +K  ++ + P + S     +  S  P 
Sbjct: 286 RKTLDAEVVEKPAKEETVVENATPDYAAGLVSTQKLGSLNNEPALPSTSYLPSTPSVVPA 345

Query: 63  SS---SGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAG 119
           SS   S     +P++   ++PP     P+P L A    Q+      G++ ATP       
Sbjct: 346 SSYIPSSETPPAPSSREASRPPEEPSAPSPTLPAQFK-QRAPMYNSGLSPATPTPAAPTS 404

Query: 120 PL 121
           PL
Sbjct: 405 PL 406


>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
          Length = 550

 Score = 34.3 bits (77), Expect = 0.068
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 4/123 (3%)

Query: 67  SPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGPLQNWDF 126
           SP+ +PT +  + P      P      S+   + ++     A + P Q  E GP Q  + 
Sbjct: 360 SPVKAPTPSGQSIPWDL-WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 418

Query: 127 GAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFT 186
              AGG +   P+AGAQ P    +       L ++VVE      N   E   G    D  
Sbjct: 419 SEVAGGTQ---PAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLP 475

Query: 187 ADF 189
             F
Sbjct: 476 PGF 478


>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
          Length = 593

 Score = 34.3 bits (77), Expect = 0.068
 Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 4/123 (3%)

Query: 67  SPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGPLQNWDF 126
           SP+ +PT +  + P      P      S+   + ++     A + P Q  E GP Q  + 
Sbjct: 403 SPVKAPTPSGQSIPWDL-WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 461

Query: 127 GAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQNEFDFT 186
              AGG +   P+AGAQ P    +       L ++VVE      N   E   G    D  
Sbjct: 462 SEVAGGTQ---PAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLP 518

Query: 187 ADF 189
             F
Sbjct: 519 PGF 521


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 34.3 bits (77), Expect = 0.068
 Identities = 42/157 (26%), Positives = 54/157 (34%), Gaps = 19/157 (12%)

Query: 3   TTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAIL--HYPGVASNGTKASGA 60
           TT  PA  +     PA++  +++ SS      A+     V       PG A   T+  G 
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417

Query: 61  PTSSSGSP-------IGSPTTTP-----PTKPPSFNLHPAPHLLASMHLQKLNSQYQGMA 108
           P   +  P          PT TP     P K P+    P           K  SQ  G A
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477

Query: 109 AATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSP 145
              P QPG A P        Q G A+  S   G+  P
Sbjct: 478 KPPPQQPGPAKPPPQ-----QPGSAKPPSQQPGSTKP 509



 Score = 30.4 bits (67), Expect = 0.98
 Identities = 29/102 (28%), Positives = 34/102 (33%), Gaps = 3/102 (2%)

Query: 48  PGVASNGTKASGAPTSSSGSPIGSPTTTP-PTKPPSFNLHPAPHLLASMHLQKLNSQYQG 106
           PG         G  ++    P   P+  P P KPP     PA          K  SQ  G
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 107 MAAATPGQPGEAGPLQNWDFGAQAGGAE--SLSPSAGAQSPA 146
                P QPG A P        +    +  S  PSA   SPA
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 34.3 bits (77), Expect = 0.068
 Identities = 42/157 (26%), Positives = 54/157 (34%), Gaps = 19/157 (12%)

Query: 3   TTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAIL--HYPGVASNGTKASGA 60
           TT  PA  +     PA++  +++ SS      A+     V       PG A   T+  G 
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417

Query: 61  PTSSSGSP-------IGSPTTTP-----PTKPPSFNLHPAPHLLASMHLQKLNSQYQGMA 108
           P   +  P          PT TP     P K P+    P           K  SQ  G A
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477

Query: 109 AATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSP 145
              P QPG A P        Q G A+  S   G+  P
Sbjct: 478 KPPPQQPGPAKPPPQ-----QPGSAKPPSQQPGSTKP 509



 Score = 30.4 bits (67), Expect = 0.98
 Identities = 29/102 (28%), Positives = 34/102 (33%), Gaps = 3/102 (2%)

Query: 48  PGVASNGTKASGAPTSSSGSPIGSPTTTP-PTKPPSFNLHPAPHLLASMHLQKLNSQYQG 106
           PG         G  ++    P   P+  P P KPP     PA          K  SQ  G
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505

Query: 107 MAAATPGQPGEAGPLQNWDFGAQAGGAE--SLSPSAGAQSPA 146
                P QPG A P        +    +  S  PSA   SPA
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.126    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,225,832
Number of Sequences: 37866
Number of extensions: 496186
Number of successful extensions: 3828
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 253
Number of HSP's that attempted gapping in prelim test: 3351
Number of HSP's gapped (non-prelim): 695
length of query: 193
length of database: 18,247,518
effective HSP length: 97
effective length of query: 96
effective length of database: 14,574,516
effective search space: 1399153536
effective search space used: 1399153536
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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