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Search of human proteins with 222136613
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222136613 exonuclease NEF-sp isoform 1 [Homo sapiens]
(774 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222136613 exonuclease NEF-sp isoform 1 [Homo sapiens] 1561 0.0
gi|222136615 exonuclease NEF-sp isoform 2 [Homo sapiens] 1484 0.0
gi|145199237 transcription elongation factor B polypeptide 3 bin... 110 6e-24
gi|239743602 PREDICTED: hypothetical protein XP_002342903 [Homo ... 108 1e-23
gi|239743600 PREDICTED: hypothetical protein XP_002342902 [Homo ... 108 1e-23
gi|239743598 PREDICTED: hypothetical protein XP_002342901 [Homo ... 108 1e-23
gi|239743596 PREDICTED: hypothetical protein XP_002342900 [Homo ... 108 1e-23
gi|239743594 PREDICTED: hypothetical protein XP_002342913, parti... 108 1e-23
gi|126273519 exonuclease GOR [Homo sapiens] 108 2e-23
gi|194239666 interferon stimulated exonuclease gene 20kDa-like 1... 77 5e-14
gi|13569960 interferon stimulated exonuclease gene 20kDa-like 2 ... 69 2e-11
gi|6857800 interferon stimulated exonuclease [Homo sapiens] 68 3e-11
gi|188536114 PAN2 polyA specific ribonuclease subunit homolog is... 68 4e-11
gi|188536112 PAN2 polyA specific ribonuclease subunit homolog is... 68 4e-11
gi|76781492 XPMC2 prevents mitotic catastrophe 2 homolog [Homo s... 64 7e-10
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 63 1e-09
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 63 1e-09
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 61 3e-09
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 48 4e-05
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 47 7e-05
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 46 2e-04
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 46 2e-04
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 46 2e-04
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 45 2e-04
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 45 3e-04
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 42 0.002
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 42 0.002
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 42 0.003
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot... 41 0.005
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot... 41 0.005
>gi|222136613 exonuclease NEF-sp isoform 1 [Homo sapiens]
Length = 774
Score = 1561 bits (4043), Expect = 0.0
Identities = 774/774 (100%), Positives = 774/774 (100%)
Query: 1 MEPEREGTERHPRKVRESRQAPNKLVGAAEAMKAGWDLEESQPEAKKARLSTILFTDNCE 60
MEPEREGTERHPRKVRESRQAPNKLVGAAEAMKAGWDLEESQPEAKKARLSTILFTDNCE
Sbjct: 1 MEPEREGTERHPRKVRESRQAPNKLVGAAEAMKAGWDLEESQPEAKKARLSTILFTDNCE 60
Query: 61 VTHDQLCELLKYAVLGKSNVPKPSWCQLFHQNHLNNVVVFVLQGMSQLHFYRFYLEFGCL 120
VTHDQLCELLKYAVLGKSNVPKPSWCQLFHQNHLNNVVVFVLQGMSQLHFYRFYLEFGCL
Sbjct: 61 VTHDQLCELLKYAVLGKSNVPKPSWCQLFHQNHLNNVVVFVLQGMSQLHFYRFYLEFGCL 120
Query: 121 RKAFRHKFRLPPPSSDFLADVVGLQTEQRAGDLPKTMEGPLPSNAKAAINLQDDPIIQKY 180
RKAFRHKFRLPPPSSDFLADVVGLQTEQRAGDLPKTMEGPLPSNAKAAINLQDDPIIQKY
Sbjct: 121 RKAFRHKFRLPPPSSDFLADVVGLQTEQRAGDLPKTMEGPLPSNAKAAINLQDDPIIQKY 180
Query: 181 GSKKVGLTRCLLTKEEMRTFHFPLQGFPDCENFLLTKCNGSIADNSPLFGLDCEMCLTSK 240
GSKKVGLTRCLLTKEEMRTFHFPLQGFPDCENFLLTKCNGSIADNSPLFGLDCEMCLTSK
Sbjct: 181 GSKKVGLTRCLLTKEEMRTFHFPLQGFPDCENFLLTKCNGSIADNSPLFGLDCEMCLTSK 240
Query: 241 GRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQLKAL 300
GRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQLKAL
Sbjct: 241 GRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQLKAL 300
Query: 301 LPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDR 360
LPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDR
Sbjct: 301 LPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDR 360
Query: 361 LGHDATEDARTILELARYFLKHGPKKIAELNLEALANHQEIQAAGQEPKNTAEVLQHPNT 420
LGHDATEDARTILELARYFLKHGPKKIAELNLEALANHQEIQAAGQEPKNTAEVLQHPNT
Sbjct: 361 LGHDATEDARTILELARYFLKHGPKKIAELNLEALANHQEIQAAGQEPKNTAEVLQHPNT 420
Query: 421 SVLECLDSVGQKLLFLTRETDAGELPSSRNCQTIKCLSNKEVLEQARVEIPLFPFSIVQF 480
SVLECLDSVGQKLLFLTRETDAGELPSSRNCQTIKCLSNKEVLEQARVEIPLFPFSIVQF
Sbjct: 421 SVLECLDSVGQKLLFLTRETDAGELPSSRNCQTIKCLSNKEVLEQARVEIPLFPFSIVQF 480
Query: 481 SFKAFSPVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLET 540
SFKAFSPVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLET
Sbjct: 481 SFKAFSPVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLET 540
Query: 541 RQPHLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQG 600
RQPHLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQG
Sbjct: 541 RQPHLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQG 600
Query: 601 SIYLSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNIL 660
SIYLSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNIL
Sbjct: 601 SIYLSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNIL 660
Query: 661 TGKDWKLKGRHALTPRHLHAWLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAW 720
TGKDWKLKGRHALTPRHLHAWLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAW
Sbjct: 661 TGKDWKLKGRHALTPRHLHAWLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAW 720
Query: 721 RWSRKIGKLYNSLCPGTLCLILLPGTKSTHGSLSGLGLMGIKEEEESAGPGLCS 774
RWSRKIGKLYNSLCPGTLCLILLPGTKSTHGSLSGLGLMGIKEEEESAGPGLCS
Sbjct: 721 RWSRKIGKLYNSLCPGTLCLILLPGTKSTHGSLSGLGLMGIKEEEESAGPGLCS 774
>gi|222136615 exonuclease NEF-sp isoform 2 [Homo sapiens]
Length = 743
Score = 1484 bits (3843), Expect = 0.0
Identities = 743/774 (95%), Positives = 743/774 (95%), Gaps = 31/774 (4%)
Query: 1 MEPEREGTERHPRKVRESRQAPNKLVGAAEAMKAGWDLEESQPEAKKARLSTILFTDNCE 60
MEPEREGTERHPRKVRESRQAPNKLVGAAEAMKAGWDLEESQPEAKKARLSTILFTDNCE
Sbjct: 1 MEPEREGTERHPRKVRESRQAPNKLVGAAEAMKAGWDLEESQPEAKKARLSTILFTDNCE 60
Query: 61 VTHDQLCELLKYAVLGKSNVPKPSWCQLFHQNHLNNVVVFVLQGMSQLHFYRFYLEFGCL 120
VTHDQLCELLKYAVLGKSNVPKPSWCQLFHQNHLNNVVVFVLQGMSQLHFYRFYLEFGCL
Sbjct: 61 VTHDQLCELLKYAVLGKSNVPKPSWCQLFHQNHLNNVVVFVLQGMSQLHFYRFYLEFGCL 120
Query: 121 RKAFRHKFRLPPPSSDFLADVVGLQTEQRAGDLPKTMEGPLPSNAKAAINLQDDPIIQKY 180
RKAFRHKFRLPPPSSDFLADVVGLQTEQRAGDLPKTMEGPLPSNAKAAINLQDDPIIQKY
Sbjct: 121 RKAFRHKFRLPPPSSDFLADVVGLQTEQRAGDLPKTMEGPLPSNAKAAINLQDDPIIQKY 180
Query: 181 GSKKVGLTRCLLTKEEMRTFHFPLQGFPDCENFLLTKCNGSIADNSPLFGLDCEMCLTSK 240
GSKKVGLTRCLLTKEEMRTFHFPLQGFPDCENFLLTKCNGSIADNSPLFGLDCEMCLTSK
Sbjct: 181 GSKKVGLTRCLLTKEEMRTFHFPLQGFPDCENFLLTKCNGSIADNSPLFGLDCEMCLTSK 240
Query: 241 GRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQLKAL 300
GRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQLKAL
Sbjct: 241 GRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQLKAL 300
Query: 301 LPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDR 360
LPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDR
Sbjct: 301 LPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDR 360
Query: 361 LGHDATEDARTILELARYFLKHGPKKIAELNLEALANHQEIQAAGQEPKNTAEVLQHPNT 420
LGHDATEDARTILELARYFLKHGPKKIAELNLEALANHQEIQAAGQEPKNTAEVLQHPNT
Sbjct: 361 LGHDATEDARTILELARYFLKHGPKKIAELNLEALANHQEIQAAGQEPKNTAEVLQHPNT 420
Query: 421 SVLECLDSVGQKLLFLTRETDAGELPSSRNCQTIKCLSNKEVLEQARVEIPLFPFSIVQF 480
SVLECLDSVGQKLLFLTRETDAGELPSSRNCQTIKCLSNKEVLEQARVEIPLFPFSIVQF
Sbjct: 421 SVLECLDSVGQKLLFLTRETDAGELPSSRNCQTIKCLSNKEVLEQARVEIPLFPFSIVQF 480
Query: 481 SFKAFSPVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLET 540
SFKAFSPVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLET
Sbjct: 481 SFKAFSPVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLET 540
Query: 541 RQPHLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQG 600
RQ VQRPVTELTLDCDTLVNELEGDSENQG
Sbjct: 541 RQ-------------------------------VQRPVTELTLDCDTLVNELEGDSENQG 569
Query: 601 SIYLSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNIL 660
SIYLSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNIL
Sbjct: 570 SIYLSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNIL 629
Query: 661 TGKDWKLKGRHALTPRHLHAWLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAW 720
TGKDWKLKGRHALTPRHLHAWLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAW
Sbjct: 630 TGKDWKLKGRHALTPRHLHAWLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAW 689
Query: 721 RWSRKIGKLYNSLCPGTLCLILLPGTKSTHGSLSGLGLMGIKEEEESAGPGLCS 774
RWSRKIGKLYNSLCPGTLCLILLPGTKSTHGSLSGLGLMGIKEEEESAGPGLCS
Sbjct: 690 RWSRKIGKLYNSLCPGTLCLILLPGTKSTHGSLSGLGLMGIKEEEESAGPGLCS 743
>gi|145199237 transcription elongation factor B polypeptide 3 binding
protein 1 [Homo sapiens]
Length = 1221
Score = 110 bits (274), Expect = 6e-24
Identities = 70/179 (39%), Positives = 103/179 (57%), Gaps = 6/179 (3%)
Query: 211 ENFLLTKCNGSIADNSP-LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKIL 269
E F+ T D P ++ LDCEM T+ G ELTR+++V V D VKP+N+I+
Sbjct: 1042 EGFVKTFEKELSGDTHPGIYALDCEMSYTTYGLELTRVTVVDTDVHVVYDTFVKPDNEIV 1101
Query: 270 DYLTSFSGITKKILNPVTTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDT 329
DY T FSG+T+ L + L+DVQ L ++ D +L+GHSL+ DL ALK+IH V+DT
Sbjct: 1102 DYNTRFSGVTEADLADTSVTLRDVQAVLLSMFSADTILIGHSLESDLLALKVIHSTVVDT 1161
Query: 330 SLLYVREQGRRFK--LKFLAKVILGKDIQCPDRL-GHDATEDARTILELARYFLKHGPK 385
S+L+ G +K L+ L L + IQ D + GH ++EDA + L + ++ K
Sbjct: 1162 SVLFPHRLGLPYKRSLRNLMADYLRQIIQ--DNVDGHSSSEDAGACMHLVIWKVREDAK 1218
>gi|239743602 PREDICTED: hypothetical protein XP_002342903 [Homo
sapiens]
Length = 675
Score = 108 bits (271), Expect = 1e-23
Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 3/153 (1%)
Query: 228 LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287
++ LDCEMC T+ G ELTR+++V V D VKP+N+I+DY T FSG+T+ + +
Sbjct: 501 IYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTS 560
Query: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK--LKF 345
L VQ L + +L+GHSL+ DL ALK+IH V+DT++L+ G +K L+
Sbjct: 561 ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRN 620
Query: 346 LAKVILGKDIQCPDRLGHDATEDARTILELARY 378
LA L + IQ + GH+++EDA L+L +
Sbjct: 621 LAADYLAQIIQ-DSQDGHNSSEDANACLQLVMW 652
>gi|239743600 PREDICTED: hypothetical protein XP_002342902 [Homo
sapiens]
Length = 675
Score = 108 bits (271), Expect = 1e-23
Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 3/153 (1%)
Query: 228 LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287
++ LDCEMC T+ G ELTR+++V V D VKP+N+I+DY T FSG+T+ + +
Sbjct: 501 IYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTS 560
Query: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK--LKF 345
L VQ L + +L+GHSL+ DL ALK+IH V+DT++L+ G +K L+
Sbjct: 561 ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRN 620
Query: 346 LAKVILGKDIQCPDRLGHDATEDARTILELARY 378
LA L + IQ + GH+++EDA L+L +
Sbjct: 621 LAADYLAQIIQ-DSQDGHNSSEDANACLQLVMW 652
>gi|239743598 PREDICTED: hypothetical protein XP_002342901 [Homo
sapiens]
Length = 675
Score = 108 bits (271), Expect = 1e-23
Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 3/153 (1%)
Query: 228 LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287
++ LDCEMC T+ G ELTR+++V V D VKP+N+I+DY T FSG+T+ + +
Sbjct: 501 IYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTS 560
Query: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK--LKF 345
L VQ L + +L+GHSL+ DL ALK+IH V+DT++L+ G +K L+
Sbjct: 561 ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRN 620
Query: 346 LAKVILGKDIQCPDRLGHDATEDARTILELARY 378
LA L + IQ + GH+++EDA L+L +
Sbjct: 621 LAADYLAQIIQ-DSQDGHNSSEDANACLQLVMW 652
>gi|239743596 PREDICTED: hypothetical protein XP_002342900 [Homo
sapiens]
Length = 675
Score = 108 bits (271), Expect = 1e-23
Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 3/153 (1%)
Query: 228 LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287
++ LDCEMC T+ G ELTR+++V V D VKP+N+I+DY T FSG+T+ + +
Sbjct: 501 IYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTS 560
Query: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK--LKF 345
L VQ L + +L+GHSL+ DL ALK+IH V+DT++L+ G +K L+
Sbjct: 561 ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRN 620
Query: 346 LAKVILGKDIQCPDRLGHDATEDARTILELARY 378
LA L + IQ + GH+++EDA L+L +
Sbjct: 621 LAADYLAQIIQ-DSQDGHNSSEDANACLQLVMW 652
>gi|239743594 PREDICTED: hypothetical protein XP_002342913, partial
[Homo sapiens]
Length = 552
Score = 108 bits (271), Expect = 1e-23
Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 3/153 (1%)
Query: 228 LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287
++ LDCEMC T+ G ELTR+++V V D VKP+N+I+DY T FSG+T+ + +
Sbjct: 378 IYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTS 437
Query: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK--LKF 345
L VQ L + +L+GHSL+ DL ALK+IH V+DT++L+ G +K L+
Sbjct: 438 ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRN 497
Query: 346 LAKVILGKDIQCPDRLGHDATEDARTILELARY 378
LA L + IQ + GH+++EDA L+L +
Sbjct: 498 LAADYLAQIIQ-DSQDGHNSSEDANACLQLVMW 529
>gi|126273519 exonuclease GOR [Homo sapiens]
Length = 675
Score = 108 bits (270), Expect = 2e-23
Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 3/153 (1%)
Query: 228 LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287
++ LDCEMC T+ G ELTR+++V V D VKP+N+I+DY T FSG+T+ + +
Sbjct: 501 IYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTS 560
Query: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK--LKF 345
L VQ L + +L+GHSL+ DL ALK+IH V+DT++L+ G +K L+
Sbjct: 561 ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRN 620
Query: 346 LAKVILGKDIQCPDRLGHDATEDARTILELARY 378
LA L + IQ + GH+++EDA L+L +
Sbjct: 621 LAADYLAQIIQ-DSQDGHNSSEDASACLQLVMW 652
>gi|194239666 interferon stimulated exonuclease gene 20kDa-like 1
[Homo sapiens]
Length = 325
Score = 77.4 bits (189), Expect = 5e-14
Identities = 62/166 (37%), Positives = 88/166 (53%), Gaps = 20/166 (12%)
Query: 226 SPLFGLDCEMCLTS-KGR--ELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKI 282
S +DCEM T +GR EL R S+V+ G + D+ ++PE I DY T +SGIT++
Sbjct: 108 SKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIADYRTRWSGITRQH 167
Query: 283 LN---PVTTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHP--YVIDTSLL--YVR 335
+ P K++ + LK V+VGH+L D +ALK +HP DT+ + ++
Sbjct: 168 MRKAVPFQVAQKEILKLLKG-----KVVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLS 222
Query: 336 EQG----RRFKLKFLAKVILGKDIQCPDRLGHDATEDARTILELAR 377
E G R LK LA +L K IQ GH + EDA T +EL R
Sbjct: 223 EPGLHTRARVSLKDLALQLLHKKIQVGQH-GHSSVEDATTAMELYR 267
>gi|13569960 interferon stimulated exonuclease gene 20kDa-like 2
[Homo sapiens]
Length = 353
Score = 68.9 bits (167), Expect = 2e-11
Identities = 56/173 (32%), Positives = 88/173 (50%), Gaps = 19/173 (10%)
Query: 217 KCNGSIADNSP--LFGLDCEMCLTS-KGR--ELTRISLVAEGGCCVMDELVKPENKILDY 271
KC+G+ + P + +DCEM T KG L R S+V G + DE + P I+DY
Sbjct: 167 KCSGA-SQKLPRKMVAIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDY 225
Query: 272 LTSFSGITKK-ILNPVTTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTS 330
T +SGI K+ ++N T K + Q+ +L ++VGH++ D +AL+ HP +
Sbjct: 226 RTRWSGIRKQHMVN--ATPFKIARGQILKIL-TGKIVVGHAIHNDFKALQYFHPKSLTRD 282
Query: 331 LLYVREQGRR--------FKLKFLAKVILGKDIQCPDRLGHDATEDARTILEL 375
++ R+ LK L K +L +DIQ + GH + EDA+ +EL
Sbjct: 283 TSHIPPLNRKADCPENATMSLKHLTKKLLNRDIQV-GKSGHSSVEDAQATMEL 334
>gi|6857800 interferon stimulated exonuclease [Homo sapiens]
Length = 181
Score = 68.2 bits (165), Expect = 3e-11
Identities = 58/167 (34%), Positives = 84/167 (50%), Gaps = 19/167 (11%)
Query: 222 IADNSPLFGLDCEMCLTSKGRE--LTRISLVAEGGCCVMDELVKPENKILDYLTSFSGIT 279
+A + + +DCEM RE L R SLV G + D+ ++PE +I DY T SG+T
Sbjct: 1 MAGSREVVAMDCEMVGLGPHRESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVT 60
Query: 280 KKIL---NPVTTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALK--MIHPYVIDTS---L 331
+ + P ++ + LK L +VGH L D +ALK M + DTS L
Sbjct: 61 PQHMVGATPFAVARLEILQLLKGKL-----VVGHDLKHDFQALKEDMSGYTIYDTSTDRL 115
Query: 332 LYVR---EQGRRFKLKFLAKVILGKDIQCPDRLGHDATEDARTILEL 375
L+ + RR L+ L++ +L K IQ LGH + EDAR +EL
Sbjct: 116 LWREAKLDHCRRVSLRVLSERLLHKSIQ-NSLLGHSSVEDARATMEL 161
>gi|188536114 PAN2 polyA specific ribonuclease subunit homolog isoform
2 [Homo sapiens]
Length = 1202
Score = 67.8 bits (164), Expect = 4e-11
Identities = 46/135 (34%), Positives = 69/135 (51%), Gaps = 10/135 (7%)
Query: 254 GCCVMDELVKPENKILDYLTSFSGI-----TKKILNPVTTKLKDVQRQLKALLPPDAVLV 308
G +D+ + + +++DYLT +SGI KI + T LK +L+ L+ V
Sbjct: 1021 GIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFV 1080
Query: 309 GHSLDLDLRALKMIHP--YVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDRLGHDAT 366
GH L D R + ++ P V+DT L+ + R L+FLA L IQ HD+
Sbjct: 1081 GHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGET---HDSI 1137
Query: 367 EDARTILELARYFLK 381
EDART L+L R +L+
Sbjct: 1138 EDARTALQLYRKYLE 1152
>gi|188536112 PAN2 polyA specific ribonuclease subunit homolog isoform
1 [Homo sapiens]
Length = 1198
Score = 67.8 bits (164), Expect = 4e-11
Identities = 46/135 (34%), Positives = 69/135 (51%), Gaps = 10/135 (7%)
Query: 254 GCCVMDELVKPENKILDYLTSFSGI-----TKKILNPVTTKLKDVQRQLKALLPPDAVLV 308
G +D+ + + +++DYLT +SGI KI + T LK +L+ L+ V
Sbjct: 1017 GIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFV 1076
Query: 309 GHSLDLDLRALKMIHP--YVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDRLGHDAT 366
GH L D R + ++ P V+DT L+ + R L+FLA L IQ HD+
Sbjct: 1077 GHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGET---HDSI 1133
Query: 367 EDARTILELARYFLK 381
EDART L+L R +L+
Sbjct: 1134 EDARTALQLYRKYLE 1148
>gi|76781492 XPMC2 prevents mitotic catastrophe 2 homolog [Homo
sapiens]
Length = 422
Score = 63.5 bits (153), Expect = 7e-10
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 13/153 (8%)
Query: 231 LDCEMC-LTSKGRE--LTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287
LDCEM + KG E R+S+V + G CV D+ VKP + DY T+ SGI + L
Sbjct: 246 LDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQ-G 304
Query: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHP--YVIDTSL---LYVREQGRRFK 342
+L+ VQ+++ +L +LVGH+L DL+ L + HP + DT + + R
Sbjct: 305 EELEVVQKEVAEML-KGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSGRPS 363
Query: 343 LKFLAKVILGKDIQCPDRLGHDATEDARTILEL 375
L+ L++ ILG +Q + H + +DA+ + L
Sbjct: 364 LRLLSEKILGLQVQ---QAEHCSIQDAQAAMRL 393
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 62.8 bits (151), Expect = 1e-09
Identities = 58/248 (23%), Positives = 113/248 (45%), Gaps = 16/248 (6%)
Query: 452 QTIKCLSNKEVLEQARVEIPLFPFSIVQFSF-KAFSPVLTEEMNKRMRIKWTEISTVYAG 510
Q+IK + K+ + + ++ + V F SP+ + M + + + VY G
Sbjct: 34 QSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPL--QSMAAQRQRALAIMCRVYVG 91
Query: 511 PFSKNCNLRALKRLFKSFGPVQSMTF----VLETRQPHLCIQYEVLEAAQLAIESLDGIL 566
+++ F FGP++S+ V + ++YEV EAAQLA+E ++ ++
Sbjct: 92 SIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVM 151
Query: 567 VDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIYLSGVSETFKEQLLQEP-RLFLGL 625
+ G IKV RP ++++L ++ IY++ V + + ++ F +
Sbjct: 152 LGGRNIKVGRPSN--IGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKI 209
Query: 626 EAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILT----GKDWKLKGRHALTPRHL--H 679
++ L +D +GK K Y F++++ S+Q A++ + G + G+ P L
Sbjct: 210 KSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTP 269
Query: 680 AWLRGLPP 687
A GLPP
Sbjct: 270 ATPGGLPP 277
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 62.8 bits (151), Expect = 1e-09
Identities = 58/248 (23%), Positives = 113/248 (45%), Gaps = 16/248 (6%)
Query: 452 QTIKCLSNKEVLEQARVEIPLFPFSIVQFSF-KAFSPVLTEEMNKRMRIKWTEISTVYAG 510
Q+IK + K+ + + ++ + V F SP+ + M + + + VY G
Sbjct: 77 QSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPL--QSMAAQRQRALAIMCRVYVG 134
Query: 511 PFSKNCNLRALKRLFKSFGPVQSMTF----VLETRQPHLCIQYEVLEAAQLAIESLDGIL 566
+++ F FGP++S+ V + ++YEV EAAQLA+E ++ ++
Sbjct: 135 SIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVM 194
Query: 567 VDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIYLSGVSETFKEQLLQEP-RLFLGL 625
+ G IKV RP ++++L ++ IY++ V + + ++ F +
Sbjct: 195 LGGRNIKVGRPSN--IGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKI 252
Query: 626 EAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILT----GKDWKLKGRHALTPRHL--H 679
++ L +D +GK K Y F++++ S+Q A++ + G + G+ P L
Sbjct: 253 KSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTP 312
Query: 680 AWLRGLPP 687
A GLPP
Sbjct: 313 ATPGGLPP 320
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 61.2 bits (147), Expect = 3e-09
Identities = 49/192 (25%), Positives = 91/192 (47%), Gaps = 13/192 (6%)
Query: 507 VYAGPFSKNCNLRALKRLFKSFGPVQSMTF----VLETRQPHLCIQYEVLEAAQLAIESL 562
VY G +++ F FGP++S+ V + ++YEV EAAQLA+E +
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 563 DGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIYLSGVSETFKEQLLQEP-RL 621
+ +++ G IKV RP ++++L ++ IY++ V + + ++
Sbjct: 174 NSVMLGGRNIKVGRPSN--IGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEA 231
Query: 622 FLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILT----GKDWKLKGRHALTPRH 677
F +++ L +D +GK K Y F++++ S+Q A++ + G + G+ P
Sbjct: 232 FGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMP 291
Query: 678 L--HAWLRGLPP 687
L A GLPP
Sbjct: 292 LLTPATPGGLPP 303
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 47.8 bits (112), Expect = 4e-05
Identities = 40/181 (22%), Positives = 84/181 (46%), Gaps = 16/181 (8%)
Query: 495 KRMRIKWTE---------ISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR--QP 543
K +RI W++ + ++ K+ + +AL F +FG + S V + +
Sbjct: 80 KPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKG 139
Query: 544 HLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIY 603
+ + +E EAA+ AIE ++G+L++ + V R + + EL ++ ++Y
Sbjct: 140 YGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREA-----ELGARAKEFTNVY 194
Query: 604 LSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILTGK 663
+ E ++ L++ G + +SGK K + F+ F+ AQ+A++ + GK
Sbjct: 195 IKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
Query: 664 D 664
+
Sbjct: 255 E 255
Score = 34.7 bits (78), Expect = 0.35
Identities = 50/221 (22%), Positives = 94/221 (42%), Gaps = 12/221 (5%)
Query: 491 EEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGP---VQSMTFVLETRQPHLCI 547
+E + + E + VY F ++ + LK LF FGP V+ MT + +
Sbjct: 177 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFV 236
Query: 548 QYEVLEAAQLAIESLDGILVDGICIKVQR--PVTELTLDCDTLVNELEGD--SENQG-SI 602
+E E AQ A++ ++G ++G I V R E + +++ D + QG ++
Sbjct: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNL 296
Query: 603 YLSGVSETFKEQLLQEPRLFLGLEAVILPK-DLKSGKQKKYCFLKFKSFGSAQQALNILT 661
Y+ + + ++ L++ F + K ++ G+ K + F+ F S A +A+ +
Sbjct: 297 YVKNLDDGIDDERLRKE--FSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMN 354
Query: 662 GKDWKLKGRH-ALTPRHLHAWLRGLPPESTRLPGLRVVPPP 701
G+ K + AL R R+ +R VP P
Sbjct: 355 GRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNP 395
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 47.0 bits (110), Expect = 7e-05
Identities = 39/181 (21%), Positives = 84/181 (46%), Gaps = 16/181 (8%)
Query: 495 KRMRIKWTE---------ISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR--QP 543
K +RI W++ + ++ K+ N +AL +FG + S V + +
Sbjct: 80 KPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKG 139
Query: 544 HLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIY 603
+ + +E EAA+ AI+ ++G+L++G + V + + + EL ++ ++Y
Sbjct: 140 YGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREA-----ELGARAKEFPNVY 194
Query: 604 LSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILTGK 663
+ E ++ L++ G + +SGK K + F+ F+ AQ+A++ + GK
Sbjct: 195 IKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
Query: 664 D 664
+
Sbjct: 255 E 255
Score = 31.6 bits (70), Expect = 2.9
Identities = 39/182 (21%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 491 EEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGP---VQSMTFVLETRQPHLCI 547
+E + + E VY F ++ + LK LF FGP V+ MT + +
Sbjct: 177 KEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFV 236
Query: 548 QYEVLEAAQLAIESLDGILVDGICIKVQR--PVTELTLDCDTLVNELEGDSENQ---GSI 602
+E E AQ A++ ++G ++G I V R E + +++ D + ++
Sbjct: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNL 296
Query: 603 YLSGVSETFKEQLLQEPRLFLGLEAVILPK-DLKSGKQKKYCFLKFKSFGSAQQALNILT 661
Y+ + + ++ L+ + F + K ++ G+ K + F+ F S A +A+ +
Sbjct: 297 YVKNLDDGIDDERLR--KAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMN 354
Query: 662 GK 663
G+
Sbjct: 355 GR 356
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 45.8 bits (107), Expect = 2e-04
Identities = 41/183 (22%), Positives = 84/183 (45%), Gaps = 20/183 (10%)
Query: 495 KRMRIKWTE---------ISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR--QP 543
K +RI W++ + V+ K+ + +AL F +FG + S V + +
Sbjct: 80 KPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKG 139
Query: 544 HLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIY 603
+ + +E EAA AIE ++G+L++ + V R + + EL ++ ++Y
Sbjct: 140 YAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA-----ELGAKAKEFTNVY 194
Query: 604 LSGVSETFKEQLLQEPRLFLGLEAVILPKDLK--SGKQKKYCFLKFKSFGSAQQALNILT 661
+ E ++ L+E LF + K ++ +GK K + F+ ++ A +A+ +
Sbjct: 195 IKNFGEEVDDESLKE--LFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 662 GKD 664
GK+
Sbjct: 253 GKE 255
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/185 (24%), Positives = 83/185 (44%), Gaps = 17/185 (9%)
Query: 491 EEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR---QPHLCI 547
+E + K E + VY F + + +LK LF FG S+ + + + +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236
Query: 548 QYEVLEAAQLAIESLDGILVDGICI-------KVQRPVTELTLDCDTLVNELEGDSENQG 600
YE E A A+E ++G + G I KV+R EL + L + E S QG
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQ-AELKRKFEQL--KQERISRYQG 293
Query: 601 -SIYLSGVSETFKEQLLQEPRLFLGLEAVILPK-DLKSGKQKKYCFLKFKSFGSAQQALN 658
++Y+ + +T ++ L++ F ++ K L+ G+ K + F+ F S A +A+
Sbjct: 294 VNLYIKNLDDTIDDEKLRKE--FSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVT 351
Query: 659 ILTGK 663
+ G+
Sbjct: 352 EMNGR 356
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 45.8 bits (107), Expect = 2e-04
Identities = 41/183 (22%), Positives = 84/183 (45%), Gaps = 20/183 (10%)
Query: 495 KRMRIKWTE---------ISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR--QP 543
K +RI W++ + V+ K+ + +AL F +FG + S V + +
Sbjct: 80 KPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKG 139
Query: 544 HLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIY 603
+ + +E EAA AIE ++G+L++ + V R + + EL ++ ++Y
Sbjct: 140 YAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA-----ELGAKAKEFTNVY 194
Query: 604 LSGVSETFKEQLLQEPRLFLGLEAVILPKDLK--SGKQKKYCFLKFKSFGSAQQALNILT 661
+ E ++ L+E LF + K ++ +GK K + F+ ++ A +A+ +
Sbjct: 195 IKNFGEEVDDESLKE--LFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 662 GKD 664
GK+
Sbjct: 253 GKE 255
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/185 (24%), Positives = 83/185 (44%), Gaps = 17/185 (9%)
Query: 491 EEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR---QPHLCI 547
+E + K E + VY F + + +LK LF FG S+ + + + +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236
Query: 548 QYEVLEAAQLAIESLDGILVDGICI-------KVQRPVTELTLDCDTLVNELEGDSENQG 600
YE E A A+E ++G + G I KV+R EL + L + E S QG
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQ-AELKRKFEQL--KQERISRYQG 293
Query: 601 -SIYLSGVSETFKEQLLQEPRLFLGLEAVILPK-DLKSGKQKKYCFLKFKSFGSAQQALN 658
++Y+ + +T ++ L++ F ++ K L+ G+ K + F+ F S A +A+
Sbjct: 294 VNLYIKNLDDTIDDEKLRKE--FSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVT 351
Query: 659 ILTGK 663
+ G+
Sbjct: 352 EMNGR 356
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 45.8 bits (107), Expect = 2e-04
Identities = 41/183 (22%), Positives = 84/183 (45%), Gaps = 20/183 (10%)
Query: 495 KRMRIKWTE---------ISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR--QP 543
K +RI W++ + V+ K+ + +AL F +FG + S V + +
Sbjct: 80 KPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKG 139
Query: 544 HLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIY 603
+ + +E EAA AIE ++G+L++ + V R + + EL ++ ++Y
Sbjct: 140 YAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA-----ELGAKAKEFTNVY 194
Query: 604 LSGVSETFKEQLLQEPRLFLGLEAVILPKDLK--SGKQKKYCFLKFKSFGSAQQALNILT 661
+ E ++ L+E LF + K ++ +GK K + F+ ++ A +A+ +
Sbjct: 195 IKNFGEEVDDESLKE--LFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 662 GKD 664
GK+
Sbjct: 253 GKE 255
Score = 39.7 bits (91), Expect = 0.011
Identities = 46/185 (24%), Positives = 83/185 (44%), Gaps = 17/185 (9%)
Query: 491 EEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR---QPHLCI 547
+E + K E + VY F + + +LK LF FG S+ + + + +
Sbjct: 177 KEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236
Query: 548 QYEVLEAAQLAIESLDGILVDGICI-------KVQRPVTELTLDCDTLVNELEGDSENQG 600
YE E A A+E ++G + G I KV+R EL + L + E S QG
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQ-AELKRKFEQL--KQERISRYQG 293
Query: 601 -SIYLSGVSETFKEQLLQEPRLFLGLEAVILPK-DLKSGKQKKYCFLKFKSFGSAQQALN 658
++Y+ + +T ++ L++ F ++ K L+ G+ K + F+ F S A +A+
Sbjct: 294 VNLYIKNLDDTIDDEKLRKE--FSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVT 351
Query: 659 ILTGK 663
+ G+
Sbjct: 352 EMNGR 356
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/187 (22%), Positives = 82/187 (43%), Gaps = 12/187 (6%)
Query: 506 TVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLET--RQPHLCIQYEVLEAAQLAIESLD 563
T+Y G S++ + +LF GP ++ +++T P+ +++ A A+ +++
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMN 67
Query: 564 GILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQG--SIYLSGVS-ETFKEQLLQEPR 620
G + G +KV T + DT + + +Q +++ +S E E +
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFA 127
Query: 621 LFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILTGKDWKLKGRHALTPRHLHA 680
F + + KD+ +GK K Y F+ F + A+ A+ + G+ W L GR T
Sbjct: 128 PFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQ-W-LGGRQIRT-----N 180
Query: 681 WLRGLPP 687
W PP
Sbjct: 181 WATRKPP 187
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/185 (22%), Positives = 80/185 (43%), Gaps = 19/185 (10%)
Query: 506 TVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLET--RQPHLCIQYEVLEAAQLAIESLD 563
T+Y G S++ + +LF GP ++ +++T P+ +++ A A+ +++
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMN 67
Query: 564 GILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIYLSGVS-ETFKEQLLQEPRLF 622
G + G +KV T + + D+ N +++ +S E E + F
Sbjct: 68 GRKIMGKEVKVNWATTP---------SSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPF 118
Query: 623 LGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILTGKDWKLKGRHALTPRHLHAWL 682
+ + KD+ +GK K Y F+ F + A+ A+ + G+ W L GR T W
Sbjct: 119 GRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQ-W-LGGRQIRT-----NWA 171
Query: 683 RGLPP 687
PP
Sbjct: 172 TRKPP 176
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/185 (23%), Positives = 78/185 (42%), Gaps = 19/185 (10%)
Query: 506 TVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLE--TRQPHLCIQYEVLEAAQLAIESLD 563
T+Y G S++ + +LF GP +S + E + P+ +++ A A+ +++
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMN 69
Query: 564 GILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIYLSGVS-ETFKEQLLQEPRLF 622
G + G +KV T + + D+ N +++ +S E E + F
Sbjct: 70 GRKILGKEVKVNWATTP---------SSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPF 120
Query: 623 LGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILTGKDWKLKGRHALTPRHLHAWL 682
+ + KD+ +GK K Y F+ F + A+ A+ + G W L GR T W
Sbjct: 121 GKISDARVVKDMATGKSKGYGFVSFYNKLDAENAI-VHMGGQW-LGGRQIRT-----NWA 173
Query: 683 RGLPP 687
PP
Sbjct: 174 TRKPP 178
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/214 (22%), Positives = 93/214 (43%), Gaps = 37/214 (17%)
Query: 475 FSIVQFSFKAFSPVLTEEMN------KRMRIKWTE---------ISTVYAGPFSKNCNLR 519
+ V F F A + MN K R+ W++ + ++ K+ + R
Sbjct: 61 YGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNR 120
Query: 520 ALKRLFKSFGPVQSMTFVLETR--QPHLCIQYEVLEAAQLAIESLDGILVDGICIKV--- 574
AL LF +FG + S V + + + + ++ L AA AI ++G+ ++ + V
Sbjct: 121 ALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRF 180
Query: 575 ----QRPVTELTLDCDTLVNELEGDSENQGSIYLSGVSETFKEQLLQEPRLFLG-LEAVI 629
+R T D T N +++ + + ++ L+E G E+V
Sbjct: 181 KFPEERAAEVRTRDRATFTN-----------VFVKNIGDDIDDEKLKELFCEYGPTESVK 229
Query: 630 LPKDLKSGKQKKYCFLKFKSFGSAQQALNILTGK 663
+ +D SGK K + F+++++ +AQ+A+ L GK
Sbjct: 230 VIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGK 262
Score = 41.2 bits (95), Expect = 0.004
Identities = 42/154 (27%), Positives = 72/154 (46%), Gaps = 15/154 (9%)
Query: 521 LKRLFKSFGPVQSMTFVLETRQPHL---CIQYEVLEAAQLAIESLDGILVDGICIKVQRP 577
LK LF +GP +S+ + + ++YE EAAQ A+ L G +DG + V R
Sbjct: 215 LKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRA 274
Query: 578 ------VTELTLDCDTLVNELEGDSENQG-SIYLSGVSETFKEQLLQEPRLFLGLEAVIL 630
+ EL + L L+ S G IY+ + ET ++ L+E F ++
Sbjct: 275 QKKIERLAELRRRFERL--RLKEKSRPPGVPIYIKNLDETINDEKLKEE--FSSFGSISR 330
Query: 631 PK-DLKSGKQKKYCFLKFKSFGSAQQALNILTGK 663
K ++ G+ K + + F SF A +A++ + G+
Sbjct: 331 AKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGR 364
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 41.6 bits (96), Expect = 0.003
Identities = 37/181 (20%), Positives = 77/181 (42%), Gaps = 16/181 (8%)
Query: 495 KRMRIKWTE---------ISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETR--QP 543
K +R+ W++ I V+ K+ + + L F +FG + S + + + +
Sbjct: 79 KSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKG 138
Query: 544 HLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIY 603
+ + ++ AA AIE ++G L+ G + V R + EL + ++Y
Sbjct: 139 YAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREA-----ELRSKASEFTNVY 193
Query: 604 LSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILTGK 663
+ ++ L++ G + SGK K + F+ F S +A++A+ + G+
Sbjct: 194 IKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGR 253
Query: 664 D 664
D
Sbjct: 254 D 254
Score = 33.9 bits (76), Expect = 0.59
Identities = 39/182 (21%), Positives = 82/182 (45%), Gaps = 11/182 (6%)
Query: 491 EEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETRQPHL---CI 547
++ +R K +E + VY F + + LK +F +G S+ + ++ +
Sbjct: 176 KDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFV 235
Query: 548 QYEVLEAAQLAIESLDGILVDGICIKVQR--PVTELTLDCDTLVNELEGDSEN--QG-SI 602
++ EAA+ A+E ++G ++G I V R E + + +L+ + QG +
Sbjct: 236 SFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKL 295
Query: 603 YLSGVSETF-KEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILT 661
Y+ + +T E+L E F + V + ++ G+ K + + F S A +A+ +
Sbjct: 296 YIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMN 353
Query: 662 GK 663
G+
Sbjct: 354 GR 355
>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 6 [Homo sapiens]
Length = 305
Score = 40.8 bits (94), Expect = 0.005
Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 487 PVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETRQPHL- 545
P +E ++ R + + V+ G ++N + +F ++G ++ + +E PHL
Sbjct: 143 PPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLS 202
Query: 546 ----CIQYEVLEAAQLAIESLDGILVDG 569
C+++E + A+ A++ +DG +DG
Sbjct: 203 KGYACVEFENPDEAEKALKHMDGGQIDG 230
>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 2 [Homo sapiens]
Length = 305
Score = 40.8 bits (94), Expect = 0.005
Identities = 20/88 (22%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 487 PVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETRQPHL- 545
P +E ++ R + + V+ G ++N + +F ++G ++ + +E PHL
Sbjct: 143 PPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLS 202
Query: 546 ----CIQYEVLEAAQLAIESLDGILVDG 569
C+++E + A+ A++ +DG +DG
Sbjct: 203 KGYACVEFENPDEAEKALKHMDGGQIDG 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,882,803
Number of Sequences: 37866
Number of extensions: 1404144
Number of successful extensions: 3537
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 3448
Number of HSP's gapped (non-prelim): 102
length of query: 774
length of database: 18,247,518
effective HSP length: 110
effective length of query: 664
effective length of database: 14,082,258
effective search space: 9350619312
effective search space used: 9350619312
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.